<?xml version="1.0" encoding="UTF-8"?>
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<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JMW4</accession>
    <name>A0A5N6JMW4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA ligase</fullName>
            <ecNumber evidence="12">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">EYC80_010420</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="12"/>
    <dbReference type="EMBL" id="VIGI01000020">
        <property type="protein sequence ID" value="KAB8289787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JMW4"/>
    <dbReference type="OrthoDB" id="206088at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903461">
        <property type="term" value="P:Okazaki fragment processing involved in mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07900">
        <property type="entry name" value="Adenylation_DNA_ligase_I_Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07969">
        <property type="entry name" value="OBF_DNA_ligase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3260.10:FF:000004">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000062">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.30:FF:000016">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050191">
        <property type="entry name" value="ATP-dep_DNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674:SF4">
        <property type="entry name" value="DNA LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674">
        <property type="entry name" value="DNA LIGASE 1/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="ATP-dependent DNA ligase DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 12" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="15">
        <location>
            <begin position="671"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="910"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAB8289787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="946" mass="105295" checksum="364FAC7F0C3D0C3E" modified="2020-04-22" version="1">MPPKQSTLGKFFGQPKGAPAKQSKLSFSSKSNPTKTSTKSTSPSEEDEDTEMKDGDSDVINKDLSPKEEESNSKIEVKKEKGVKRSRSISPKLSAKTKAIKIEDEIKEEMEVDEEEEDEDEEPIVKKPRRSKKAEPMDRKVKEVKEVKREKKEKKEKKEKTEETEETEEKPSPKLTATKSKVKSSSDSSPKKASSNNISPPSKANKKNKVIDDEDMEIEEVPPMKPTKRRTSNASKSISESDIEEDLESSGDEKPEVAAKAREKIQTTLKSKNKDPYPDWKPGEPVPYAALCTTFSLVEMTSKRLVIAAHCSLFLRQVLRLTPDDLLPTVLLMINKLAADYAGIELGIGESLIMKAIGESTGRNLSVIKNDQKEIGDLGLVAVKSRSNQPVMFKPKPLTIRGVLRSLIEIATMQGNGAQGRKVDGIKKLLSAADAHSAGKVDITKDKGGPSEAKYIVRFLEGKLRLGLAEKTVLVSLAQAMVCHEIEAKESGKVPSTEQMAKGESILKAVHSSLPSYDVIIPAMLEHGIFNLKDNCKLQPGVPLKPMLAKPTKAITEVLDRFESQTFTCEYKYDGERAQIHYVAKDSPKQYLGATPAAAKSSAGGLAAIFSRNSEDLSKKYPDVLGKLNTWVKEDTKSFVLDCETVAWDVIEKKVLPFQQLMTRKKKDVKVEDVKVKVCVFAFDLLFLNGEAVVEKSLRERRELLHKAFQPIEGEFQFATSMNGQEIDEIQTFLDESVKASCEGLMVKMLDGTESGYEPSKRSRNWLKIKKDYLSGIGDSLDLVVLGAYYGRGKRTSVYGAFLLACHNPQTDTYETICNIGTGFSEQVLEELHTQLSAIVIDRAKPFYSHSSGNQHQPDVWFEPKYVWEVKTADLTLSPRYKAGCKEGVDNGGEKGISLRFPRFIKIRDDKKPDMATSSRQVAEMYRKQESVTKSKGPSVDDDFEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JPB9</accession>
    <name>A0A5N6JPB9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_010845</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000017">
        <property type="protein sequence ID" value="KAB8290412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JPB9"/>
    <dbReference type="OrthoDB" id="410701at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF56">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0045">Antibiotic biosynthesis</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="3">
        <location>
            <begin position="16"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8290412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="198" mass="22374" checksum="F53C2D38B068F5AA" modified="2020-04-22" version="1">MKLGATREKGNVVLGRGPLPLHTDGIFVGHRPDMVILYASEFEDELGSGETIIVDQLKALAEMPSDLRAELENKTFEYQIQEAGHYDLGDTWFPIPPLRTHEGKLYLNFALQFPEGIEASWRVRVAGVEKSESDKLIARLEEFLLQPRYTYQHRWSVGDFICFDNSDTLHGRTSIGENGVRVLFRGQVNRPTAAEVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JRG2</accession>
    <name>A0A5N6JRG2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_010046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JRG2"/>
    <dbReference type="OrthoDB" id="3489680at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8291366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="643" mass="72518" checksum="99F1D5D7BFEF0A31" modified="2020-04-22" version="1">MTMEPENDHLKMKPIKILEIDNTNEFPELSSSPNPPTQKPVIASNWGSLFASKVPKEPRLFHHSSLPPLSITPTKEMIHGSRLIEEKEDPLISPTTAECMSILSCETTETAVERDEVDTPWGSPTAKNYLNISAAKDENTDCDTTIIFPDFIATDTDTDTPEPPQRELLPPFKFPATEVKPEVDIYNASPKLTKAKKMEVEELSEAERHDTPSYIRGGLPLRQVVENDPDRVIHAIRHMMNGIVQMRRQLGAAPEEIKFLINNHQRALNEIDFLTENERIARLAVERREAANKEARLVMEKERSTYAKDLENSKSTKFNPSAKPFSPSNFMSTEFTGSTPPFAVSFPPTTQIQSPLKYSVLHEPGFMVEQSRTPPVPYKFHPLLNRSRTWSTHRPSIGPIVPAGPYSHFNAYNSRPMSPMFARQVQSPFPMLTSQLPLYSLTNVEVDLQQETIVRTPPQSPTSIQSQLPRSLANTLLLRTPVPGKTDYKSTPTSPTKELSADLSFKATSTNTSPRRKTSDFHKAYHQSQFYQPKPHNLKMTIPTTYTADDFQKAILQLPRTHRHLCPSSLISPDFKCRVPYCLLQQICPDFTSAPQLVFTHGAVKKIGRPALQSMVPRPPLHITKYKYIKPAARSRQIGDGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JRG7</accession>
    <name>A0A5N6JRG7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mob1/phocein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_010056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JRG7"/>
    <dbReference type="OrthoDB" id="10261121at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8291377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="39977" checksum="87C3CD338754A892" modified="2020-04-22" version="1">MSNLFSGISGRFRGSGKSSGAKSPGGLNGASPTSPTGNSPINSSSPASMAPRNSPLPNQASLSQTMSVDDQQLPPAGNDPLAAYNLPRPKPLWLNNAYAKHIVKGNFMTLSARPKTVEPGEWIAHQVVEHYRILWNFVRVIHEKEEDGNTICNPQTCPRMSAGANHSFTWLNSRKEPVEVPAHEYISLMQRWISGKIDNTAIFPTDPAGISYCHNSGGPEVAGSTYASGGVNTPNSSTPIPAGPTTLTTSLSQLSGPGDWIGKSSGFPQEFVDVCQTIFRQMFRVYAHLYWGHFIEPFYHLNLDKHMNSCFSHFVLTATEIDMLKPHELEPMQPLIDLWAANGTFPPESKAYACANLKAGEKLLQAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JRG9</accession>
    <name>A0A5N6JRG9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_010333</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
            <location evidence="1">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000019">
        <property type="protein sequence ID" value="KAB8290007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JRG9"/>
    <dbReference type="OrthoDB" id="248495at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051754">
        <property type="term" value="P:meiotic sister chromatid cohesion, centromeric"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13981">
        <property type="entry name" value="STKc_Bub1_BubR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000734">
        <property type="entry name" value="Checkpoint protein kinase (SldA), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.430:FF:000003">
        <property type="entry name" value="Checkpoint serine/threonine-protein kinase BUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015661">
        <property type="entry name" value="Bub1/Mad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013212">
        <property type="entry name" value="Mad3/Bub1_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012572">
        <property type="entry name" value="Mad3/Bub1_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14030:SF4">
        <property type="entry name" value="BUB1 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14030">
        <property type="entry name" value="MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08311">
        <property type="entry name" value="Mad3_BUB1_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08171">
        <property type="entry name" value="Mad3_BUB1_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00777">
        <property type="entry name" value="Mad3_BUB1_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51489">
        <property type="entry name" value="BUB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0137">Centromere</keyword>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="3" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BUB1 N-terminal" evidence="7">
        <location>
            <begin position="63"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="826"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="467"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="674"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="509"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="529"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="681"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8290007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1185" mass="133191" checksum="90AA4238D44DE8CB" modified="2020-04-22" version="1">MSASEDLIDFDIIENQKENIQSLPQGRSARNLAKIFSPSPLQPLSTPTPSDTRNLNDAIREEYEAELLNIGESDDPLDIFDRYVKWTLDAYPSAQATPNSQLAPLLERATKTFLNSPQYKNDPRYLKLWLSYIRFFSDTPRETFAFLARHNIGEGLALFYEEFAGWLEGAGRWIQAEEVYQMGIDKEARPAPRLLRKFNEFQERFAARPDSSNEPSSPALPTVRPALAAKIDPYAAVAAAPEDPQAPKPSAGVGGSSTTKSGKQKLKIFSDDENGVTPAVSASPGSGWEIPRYQFSRTRTNFWQIWCHVFQSIPLPQITNPELQQVTINPKNGRSERIFVDLEAVYPTPDKVGTELSFEELRAAHRGWLDKLWEPELNIPQDKLVSNEPIQESKISIETITQQVPAKLVIARDTTPQDKNGPEKFVIARDPVYLDENGAKKEHNKETKHRRMKVKEVNKTQIISAKLSSPTGKKMTKRKSSKEQTMTLHTKAATDEIYDIFNQPLKPADEEEEEEEDESDEDDGDTTDGDYTSGGESTMTGRLGGTSDVGDDDDETTDVKSESEWTEFTAQKHVSDVDDDNDDDTRASTFTDAEDEEFEAIKVAIPRDFEEDDELVTPVSEDGPSKSTTSFVPIPPEDYDPPTHPYRDPAQVSQNRLPFMTPIVERTESSLGLPTMRGQKNYFNSATSPSRGSGSKIQVFQDDEDSSTLREIINESKPTDRIPQPQLGKKKPLSNSALFAKEITPKGPIIHDSQCNPVDESIRQLIFEKLQPPLSSYEGFLQHDEARGQSAELKKYSKAVSRAGKGDRNSIPAPPTLEFPGTDRYYTLKRELGAGAFAPVFLLESSAGEGEQDENEAPAVMGKGAFDHFNRKSLEALKMEDPPSAWEFYIMRQAKRRLGVSRPAESILDVYEMHLYRDECYLIEEYRDQGTLLDIINISRADAKSPGGVMDEILVMFFTIELFRTIEALHSKGILHGDLKADNCLVRFDALSDDDVWSPKYRRDGSGCWNKKGISLIDFGRGIDMKCFKPDVQFIADWKTGPQDCAEMRELRPWTYQIDYHGLAGIIHSMLFGKYIDTIAERPGGGNTDAIGGLGGGGAGLRKWKIKEGLKRYWQTEIWAGVFDLLLNPQGYVDGEEGGRMPVIRGMRVMREEMEEWLEGNCEKGSGLLKGIRKLEEGFRERRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JTD5</accession>
    <name>A0A5N6JTD5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GPI inositol-deacylase transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JTD5"/>
    <dbReference type="OrthoDB" id="348976at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050185">
        <property type="term" value="F:phosphatidylinositol deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006505">
        <property type="term" value="P:GPI anchor metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039529">
        <property type="entry name" value="PGAP1/BST1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056824">
        <property type="entry name" value="PGAP1_TMD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495:SF7">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495">
        <property type="entry name" value="NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25140">
        <property type="entry name" value="PGAP1_TMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase transmembrane" evidence="2">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8292338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="94" mass="10553" checksum="0AF4194A766E4330" modified="2020-04-22" version="1">MPFILLVETLTSGKMVPRVTSRVRHVTSVLFFGISIYAAVYGVTYAYMLHYLVNLVAAWLVAIHSSTSNWTLADVTTMFDPEINETTRKRGKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JTH8</accession>
    <name>A0A5N6JTH8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Spindle assembly checkpoint component MAD1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_008114</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JTH8"/>
    <dbReference type="OrthoDB" id="331602at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.457.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008672">
        <property type="entry name" value="Mad1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168:SF0">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05557">
        <property type="entry name" value="MAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="343"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="5"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="343"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8292378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="616" mass="70066" checksum="DF2D1B22C5D19F51" modified="2020-04-22" version="1">MSEIRDNSSNEKIGLERRIREVEESKRLLEEEIEDIKTESEESSRILERRVSELETRNQTLQRSVQDLQEDSDRREALLQDVQQQLADKDTAYGALEAEVLRLKAQTGDTDTLEVIKRELSEQVTHIRNLEATNREQSAELKHYKRLHKSVEVVEEEKRSLQRKVEAMDDLQNELGEARLQRQRLEDERLAWTAYLQNQSDVEGQFEFNSPEDLARALVEERMQTATLVERLGAMESEVLDKDNIIDGLQNDKRSLSEEMEKVKASGSSAGGGDSKVRLRLERQRALAVKEVEYLRAQLKTFDAEDEAFGAGDNIDDGKIKRIEELESIVDQYRQEVQSLQADLTTAESAQPTTTNLAGTKHPRDEGEENERIGVLTRKNQRLATATAHSQTRVLSLRSNPTSDFEAIKLSTITALRAENADLLSQLTTNLPPNASVPLSTLQTQKDLVAESQAALKDERTRNDRLKKVWGLKSQEFRDGVSSLLGWDAVFMPNGKMRVTSFYYPSVGEDENSIVFDGERGTMKVSGGPESKFAGRIMENIKFWVNERGSIPCFLAALTLEFYEEKKGDGTVMDMAFKANKWGPGVQESYLLYKLVYSTSWVNRYENLNRNVKESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JTJ8</accession>
    <name>A0A5N6JTJ8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_008133</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JTJ8"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF19">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0843">Virulence</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8292399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="485" mass="55054" checksum="901CCFF862722041" modified="2020-04-22" version="1">MPDSEPDQERRRRRPAVGSVHTLSVDDERSDAVENFHVAIVHWINRVSELKLYIYAKPDTEFLVQPKLIFAIGTTTLSNYSFLLEKQKVVLETSLKLWYLVYPPISTPGSPFHRDSTAKDEFLLPKLTICGSGLLRTVALQAGYIMAKELKIQLQEETSLGLVSLRPDLLDAIKDAKTWNLRCIKTGEVNMKGYLSICLTIAHTDALRKGQVGEELDASLTSLISICMEPARSPATERFMEHGIFNADGDFWEQTRTVTKLIFSRAQISNTEYLKKRFLDTFTEFIFGQSVNTFEPGESSFDAERFPATSDRALKGVGLRVVLGSYAFLQDLDRSWRLACHVVHDFIDQQIDHATQNHDAGTNSDLDLDSKPQKFILLSELFKKTQGRDTPSSRYNGDLIFDSLKQLKYVRFMVDESLRLLTPSGRSNRIVFVDTILPTGGPSQTEPIFIRKGTEICFVFKSLHIDKDIWGPDGDEFNVERWEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JVL5</accession>
    <name>A0A5N6JVL5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JVL5"/>
    <dbReference type="OrthoDB" id="47494at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8293045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="105" mass="11395" checksum="3DE965F980EE36EF" modified="2020-04-22" version="1">MKGANTYYKQFKSSTVSLKGRGLCLKPGSTHIGLSAIVSGNETGSLVIVLNLDPLRHCPQRFYAHVHSNRTQYQSHFLATPVKISIANTSNTVSCAHNTSLFSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JVL8</accession>
    <name>A0A5N6JVL8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_008163</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JVL8"/>
    <dbReference type="OrthoDB" id="4187847at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008496">
        <property type="term" value="F:mannan endo-1,6-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF38">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="158"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8292441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="406" mass="41729" checksum="A17A9896D2F47D51" modified="2020-04-22" version="1">MYNHTTDSAWKSRTESFLKASANFFTSDNVMYEQACETVGTCNNDQYSFKAYLSRFMWATTQMAPFTKSTITTYLTKSASAAAGVCTGDANACGAKWYTGSSDKILGVGQQMGALEAKRSFKHHLLQHPLPPPVLAAHPSFSSSSKKPTVAGASSVAVAASSTRVSETNTRESALPVYSSTVHSSPEAPSFTAQPSTPASAEETSSATASTSSAVQTSTAISSDVPSSTRTPSPAAQNPSEVYIPTALPSSTIELSSAIVSAVSSASSFTTPAPVFDTTTTVHIIHSTTVSCSNSSVYANSTTWFAPPSSFLSSHRTTALSTSVTATTHSSASLKSSTALLIDTSTQPTHKSTETSIKGTSIAPTAASAAAAAATTSANAAVGRNMRVPGTGLVAGILGAGLLYVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JVM1</accession>
    <name>A0A5N6JVM1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_008136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JVM1"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8292404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="68" mass="7697" checksum="16F211310BF33A40" modified="2020-04-22" version="1">MSDHLFLYVIRSLGHVKSGLCVGNWNIVCINADNISLTRGVLLFVPTMIMQWRVLFALVIEGNYSTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JVM9</accession>
    <name>A0A5N6JVM9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JVM9"/>
    <dbReference type="OrthoDB" id="5216128at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025363">
        <property type="entry name" value="DUF4267"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14087">
        <property type="entry name" value="DUF4267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8292424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="225" mass="24881" checksum="1FF4B8E41E693087" modified="2020-04-22" version="1">MKAQVPEVGSRSSITPCPTTPYQWKGTLTHVGTLNLPDTESREVPSSISLASFRPRSISSLSSRSQEALHVLAMPAIRHGDLEYFAGYASSWRFFISRTLKSSSNLNSITFSRILRFLPNIFGTIFIGFGINVLLRPSHALTFYRPFSLPTAAFDKALVAAFMTIYGARDIFMGLAMHAASYYRNYRTLGWILISGSGVAFVDGWVCYKAGGASRSLGFWIARAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JVN3</accession>
    <name>A0A5N6JVN3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JVN3"/>
    <dbReference type="OrthoDB" id="3918601at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39614">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39614:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="2">
        <location>
            <begin position="49"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8292434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="441" mass="48423" checksum="5D842D7157B834C9" modified="2020-04-22" version="1">MSMPTTGLVVPPGQSPPFAVVTNTDHSAWIIIATALGLACVLVFSGIKAFARGSLGKEITYDEICLAASTLISVIQSSVILGACSKGLGKSIELVPAKNQAQIQQMCYTSLVLFIVSLGLSKSSVVVLLGSLTPDQKHKKIFRAAIGLMVAWTISSTFAVALQCNLTYPWRTIGQRCDNALLRWQMIASFDIVFELTFVLLAVYLVWSLRTSKSNKTIVVVAFSFRLPMIIAIAYRLATFDANGLTKNPSILEDKFIIWTQTELNYSVISAIIPSLRPFVKNLSTNYGQELGGRSGYTLEDSQNYQLSNLGSVARKENSPQEARIRDDVNPDDYKFRVWGNQDRQGASAKKNKTLGEGCSRFRKTAVDEGVDSFSVDSGDSQRMIIQKDITWTVKNTVLNGVFGEFGELRETSNFSHSKMIIWILHDNLKSSASVALQVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW02</accession>
    <name>A0A5N6JW02_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lipoyl-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_007477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW02"/>
    <dbReference type="OrthoDB" id="5391403at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="97"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8293119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="156" mass="17854" checksum="D0C2A49421ECE22E" modified="2020-04-22" version="1">MTNTIINCSRPLEILIGVTLLIGNVFTVVGGWFFISLFSKIKKQLKSSFLQNLSLAPSFSRTITSSSRFLRAQRSAAPQLRYPFPVIQQFRNYADKVVKVPEMAESISEGTLKQWSKQIGDYVEQDEEIATIETDKVGILGERRRYRYRWSRLGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW03</accession>
    <name>A0A5N6JW03_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Complex I-B22</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NADH-ubiquinone oxidoreductase B22 subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">EYC80_007478</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Mammalian complex I is composed of 45 different subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW03"/>
    <dbReference type="OrthoDB" id="13598at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20263">
        <property type="entry name" value="Complex1_LYR_NDUFB9_LYRM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045292">
        <property type="entry name" value="Complex1_LYR_NDUFB9_LYRM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033034">
        <property type="entry name" value="NDUFB9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12868:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12868">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0007">Acetylation</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="17">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="65"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAB8293120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="99" mass="11644" checksum="1D7C6EA045F941AF" modified="2020-04-22" version="1">MSTRATVSSLYRRSLKLSLDWCVHRYLWRGQALYIRSLFEAQKNVHDPRLQRALFKETEDLLEKWKHPDPYRPPTAPGGSKYERNLPAPILDPPPKMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW12</accession>
    <name>A0A5N6JW12_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein SQS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_007483</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SQS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW12"/>
    <dbReference type="OrthoDB" id="21470at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02646">
        <property type="entry name" value="R3H_G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034082">
        <property type="entry name" value="R3H_G-patch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051189">
        <property type="entry name" value="Splicing_assoc_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14195">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H" evidence="12">
        <location>
            <begin position="324"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="G-patch" evidence="11">
        <location>
            <begin position="457"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="27"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="410"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8293129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="500" mass="55222" checksum="2A7C451FF5A6996D" modified="2020-04-22" version="1">MIADYIANMDREQGMYDVGQAFNRRELGGDDDAAWQDDSSVDDIQHPNQPEQHGWSRTELQDLDDLSTSDEARGKVQTVLSKRHRTGGVQYLVIWEHQDVDEARWVPLDVLQCSGALPLIEAFEAEEKLIAEFDSNGDEDSDDSDDVGDDDDDDYDDDHDLAQRRIDRMDDEKIARLLSKQEELGMGGDEILLFDDDVDDEDEEIAAPAVNLNNFILSGRRGRIERQRRQGEFPSAAPLADAYDGFDVMDFDRPSLKKKPKGRKGKLILDDISDSELEASMQSAWDNDRVKKKERKREREILRAKGLLTGKNGKPDMKARYKEGMSIDDVREEIKEFLQGGNTTLSLPAMDKANRKFVHEIANAFKLKSKSAGLGNKRYPILYRTSRTTVYGDRAYEAAASKLSRRFLPRNDVGGRKAGAAPRRGGRGGGGGGGGGLGAASYRDGDVVGASAPELGVENRGRAMLEKMGWSAGTALGALDNKGILQPVSHVVKTTKAGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW15</accession>
    <name>A0A5N6JW15_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine protease</fullName>
            <ecNumber evidence="11">3.4.22.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_007484</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine</text>
            <dbReference type="Rhea" id="RHEA:67548"/>
            <dbReference type="Rhea" id="RHEA-COMP:17323"/>
            <dbReference type="Rhea" id="RHEA-COMP:17324"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:172940"/>
            <dbReference type="ChEBI" id="CHEBI:172941"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:67549"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the peptidase C54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="11"/>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW15"/>
    <dbReference type="OrthoDB" id="2960936at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019786">
        <property type="term" value="F:protein-phosphatidylethanolamide deconjugating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035973">
        <property type="term" value="P:aggrephagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005078">
        <property type="entry name" value="Peptidase_C54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046792">
        <property type="entry name" value="Peptidase_C54_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624:SF49">
        <property type="entry name" value="CYSTEINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624">
        <property type="entry name" value="CYSTEINE PROTEASE ATG4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03416">
        <property type="entry name" value="Peptidase_C54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 11" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase C54 catalytic" evidence="13">
        <location>
            <begin position="102"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="42"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8293130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="188" mass="20463" checksum="99C3E26CE7412005" modified="2020-04-22" version="1">MTTVDLGRYKRFVQYFWDPEPTNDPASKSPIWCLGEEYLVPEKSSTSAPVTDSPPQEGGYLPARSLPAVKSTTPPDSKVGSLESGSAYDDCDTSNIDGGWPTAFLDDFEAKIWLTYRSNFPAIPKSQDPKAFSAMSLSVRLRSQLVDQGGFTSDTGWGCMIRSGQSLLANALLTLRMGRGSSSPDCFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW17</accession>
    <name>A0A5N6JW17_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histone H2A C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_007480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW17"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024946793" description="Histone H2A C-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="3">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8293123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="76" mass="8020" checksum="822EACA4C21CF229" modified="2020-04-22" version="1">MLNVLVLVPLSTLPPFSSTSLLKSLSWLVTLLATTRRPLLGHVTIAQGGVLPNIHQNLLPKKTAKAAGGKPASQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXQ2</accession>
    <name>A0A5N6JXQ2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXQ2"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="103" mass="11373" checksum="6C2ED15D9EB3E89A" modified="2020-04-22" version="1">MGTVRNVAVAVLILSFFTFVAFFGRLPALRNTPIGSLHRVIWVHIPRAFRAADKKLTNGRLSASVGKLAHTLWNDRHPVVMRVLLSDVLLLCTERKAASAPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXS6</accession>
    <name>A0A5N6JXS6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXS6"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="73" mass="7512" checksum="0ACAE494274A083E" modified="2020-04-22" version="1">MLGVAQPKLVLHSLKLRRRFNTMASPPKVAADDDFGGWSSAAPAPAANATPGTGKPAGGFSSGGEDLFSNVWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXS9</accession>
    <name>A0A5N6JXS9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXS9"/>
    <dbReference type="OrthoDB" id="3563651at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="32714" checksum="33B65AAF37DA7275" modified="2020-04-22" version="1">MSTTTSASTATITLAPSTLVGSLTTTYTPSGSDCSQIFWAQNPINRWLAYGGIAAASSTCMPSGFKRATAYYYSPGICPTGYNAACSSFSTGLSVTKTVATCCPVGYTCFANRPADQIYGCTSYFSKDETLSINSVLFDTVTAASTTSYPVVYASTTITVTSGVDKVAAYGIIIERATDDPTWESNTASTSTSSPTALPIASGPTTLVSASLSSSTSIASTSTSISSPSTGLSTSAKAGVAVGVVLGALLIGAGAFILFKRLRKRPQRLQPVPIAENGEQIHYYEKYNDGRQYDVTPYVVEAPVPTPNQQGGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXT9</accession>
    <name>A0A5N6JXT9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009437</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXT9"/>
    <dbReference type="OrthoDB" id="5325318at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8293969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="133" mass="15463" checksum="91D172A0BDF33E45" modified="2020-04-22" version="1">MAITTTTATVIGGIFRSVFIHDISIDQYLKGKPRAGFPGYTTFKNSTNLHHTHLLYSLNIEDCLFLKVLFQFSNLNLNKRSNFQLFPYSSCSIYNNFINFNFPTSHLKDETNHIHSLFNRTLSYQDQFRLLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JY23</accession>
    <name>A0A5N6JY23_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_009512</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JY23"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024806839" evidence="2">
        <location>
            <begin position="23"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8294054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="135" mass="13514" checksum="F5D4ED04E74E775C" modified="2020-04-22" version="1">MRFSISQLSILAIAALFTSAAAVDIEARQTPAPPVTPVPTPTSTVKSTLDPSQSASRSMAIQSALASYASYLSAASASALAAGSTLPPLPSYTLASPGASAAAKAAEDTSGSERSMDITWTKLGLGMVVSVLGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JY25</accession>
    <name>A0A5N6JY25_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="11">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">EYC80_009454</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="11"/>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JY25"/>
    <dbReference type="OrthoDB" id="4310724at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17946">
        <property type="entry name" value="DEADc_DDX24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="206"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="237"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="470"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="83"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="693"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="9">
        <location>
            <begin position="206"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="122"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="705"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAB8293987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="773" mass="85894" checksum="2870ADD46983AA62" modified="2020-04-22" version="1">MDNKQKKRSHSETNGSQKAPKRQKIQKSSKKQKKDAPKKKVAVDSLPWNEVTMPDMFEDAEGFYGLEEVDDVEVVRDGDVVTFVSSKIQTQDDDDDEFEGFGEDEEDKETNDISIVKPILKPTEESTEKEEQSAKKEKKAKPEKKENKEKPKATEEEEKLPNKKDKKSKKEKPKQQPTDKDAELKQDFKNVFQALEEDAAREVDVSGWAELDLSSNTLSALSKLGFSKPTPIQSEAIPEVLAGHDVVGKASTGSGKTLAFGIPIVEKWLEVYGELDEDELKKSTRPPTALILSPTRELAHQLTEHITALCKGMSTSPYVAAVTGGLSVQKQQRQLAKADIIIGTPGRLWEVISSSNELSAGLKQVRFLVIDEADRLLTDGHFKEAEEILNALDRTHADEDGEEEDTIQPRQTLVFSATFHKGLQQKLAGKGKQSFKDESQSMEYLLKKLNFREEKPKFVDVNPISQMAANLKEGMVECGGEEKDLYLYSLLLHHPNQRTLIFTNSIHSVRRLTPMLQTLNIPAHSLHSQMIQKARMRSIEKFSRTNNTGSVLVATDVAARGLDIGGVQLVIHYHLPRTADMYVHRSGRTARAAASGSSILLCGPEEVVGTRRLVAKVHAQNALNGEGKKSKFYIRSLDIDRRVVARLKPRVTLAKKIADSALAKEKKGHDDDWVKNAAEELGVEYDSEEFEALGGGRKGRGTGRRMKEKEARGMTKGEVGALRAELRALLAQRVNVGVSERYLTSGTVNVNDLLKGAKGEWLGEVEGIGMEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JY26</accession>
    <name>A0A5N6JY26_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mediator of RNA polymerase II transcription subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_009519</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Mediator complex subunit 7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JY26"/>
    <dbReference type="OrthoDB" id="10253553at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009244">
        <property type="entry name" value="Mediatior_Med7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044888">
        <property type="entry name" value="Mediatior_Med7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428:SF11">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05983">
        <property type="entry name" value="Med7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0010">Activator</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8294063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="367" mass="41016" checksum="4325AE11B2C130C7" modified="2020-04-22" version="1">MADQQQPPPPQPNQLAAAHPGPPSFWKHFTPDNIERIEKLRAEKSTNQKGADKPSYKLPPRILDLPVELRYLQPPEPPTSGSYRTLGQIHKIKDELPTLEESEVERLYTPPDTPTGTGTHGDRALILKRIAKSLLLNYLELVGIMSINPEQSHEKISDLNTLFVNFHHLLNEYRPHQARESLILMMQDQLDRSRAETEGIMKMKEKVEGLLESLGQINFADEEIVGCLGAVRPGIWLKDGCTADSRRLHASSLMVTYANHLRSNPETRLFDEGYLTRRLTIKNYNNVDTYNSNPHTNTASPNLKANQKPYEMCTSNSTGLVNRNGPGSAASSTISDIVKGTNTTGKTKCLECDGYECCCIPIPCTVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JY32</accession>
    <name>A0A5N6JY32_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP citrate synthase</fullName>
            <ecNumber evidence="2">2.3.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ATP-citrate (pro-S-)-lyase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Citrate cleavage enzyme subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">EYC80_009385</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the formation of cytosolic acetyl-CoA, which is mainly used for the biosynthesis of fatty acids and sterols.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA</text>
            <dbReference type="Rhea" id="RHEA:21160"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.3.3.8"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Composed of two subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.8" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JY32"/>
    <dbReference type="OrthoDB" id="3261737at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003878">
        <property type="term" value="F:ATP citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06100">
        <property type="entry name" value="CCL_ACL-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000003">
        <property type="entry name" value="ATP-citrate synthase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000005">
        <property type="entry name" value="ATP-citrate synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000024">
        <property type="entry name" value="Probable ATP-citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118:SF42">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA-binding" evidence="19">
        <location>
            <begin position="162"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="55"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00054002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00060724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00062455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00076189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00083544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAB8293910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="783" mass="86148" checksum="6C0E8D3B59A88E34" modified="2020-04-22" version="1">MNSFNSPGFPSSIDFSTLNHRNLLNTDMFGCTSHGGCLARKLIVSSSQSLPRSQISALISSQRRKERQTDRRKERKKERKKERKKERKERKGKFSLFETQLAGKGFLRCLFTYGSPFTIFDCLLFFTMPSATASAAQGNANDNIRRFAAPSRPLSPRAEHTLFHDKTRCFVYGLQPRAVQGMLDFDFICKRKTPSVAGIIYTFGGQFVSKMYWGTSETLLPVYQDVGKAMAKHEDVDTVVNFASSRSVYQSTMELLQYPQIKSIAIIAEGVPERRAREILHAAAKKGVTIIGPATVGGIKPGSFKIGNTGGMMDNIVASKLYRKGSVGYVSKSGGMSNELNNIIANTTDGVYEGVAIGGDRYPSTTFIDHLLRYQADPECKILVLLGEVGGVEEYRVIEAVKNGTITKPIVAWAIGTCASMFKTEVQFGHAGSFANSQLETAATKNKSMKEAGFHVPDTFEDMPAVLASVYQKLVQDGTVVPQPEPIVPKIPIDYSWAQELGLIRKPAAFISTISDDRGQELLYAGMPISDVFKEDIGIGGVMSLLWFRRRLPDYASKFLEMVLMLTADHGPAVSGAMNTIITTRAGKDLISALVSGLLTIGSRFGGALDGAAEEFTKAFDKGLSPRDFVDTMRKQNKLIPGIGHKVKSRNNPDLRVELVKEFVKKRFPSCKMLDYALAVESVTTSKKDNLILNVDGAVAVCFVDLMRNCGAFSAEEAEDYMKMGVLNGLFVLGRSIGLIAHYLDQKRLRTGLYRHPWDDITYLLPSLSSGAPGTEGRVEVQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JY54</accession>
    <name>A0A5N6JY54_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_009547</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the bZIP family. YAP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JY54"/>
    <dbReference type="OrthoDB" id="5380163at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000067">
        <property type="entry name" value="BZIP transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.100">
        <property type="entry name" value="YAP1 redox domain. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013910">
        <property type="entry name" value="TF_PAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023167">
        <property type="entry name" value="Yap1_redox_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08601">
        <property type="entry name" value="PAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111430">
        <property type="entry name" value="YAP1 redox domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="159"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="31"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="274"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="348"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="277"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="379"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="397"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8294093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="604" mass="65524" checksum="131BC977765BA65F" modified="2020-04-22" version="1">MAAANTSRHNPINPDFTLSPRQEELLFAALNSNKSSNNLDNSTQLPPSSNALQDMSTSAFNESPLQAPGSGTLNGFDESPFIDYDYEFEGDDSFNFDLGNDSQGQMIGNLPGTSSDGDAENHEKRSHPDDDGDEDEGGGKRREGDDKSSKKPGRKPLTSEPTSKRKAQNRAAQRAFRERKEKHLKDLETKVEDLEKASESANHENSILRAQIERMSMELREYKKRLSINGAMNRSPNGNVPAYFAGKGLPNVSANPNDVNFQFEFPRFGRLPGPPVTNGSSSIVPAISPTTQNVQSPSDKNQTSPRNPSNASNTFGIGFTPTSAQIGGDDMSSFSGLFAPEMMDNASKSALEPFGNGTTNGSMSSTDSPNISTGGQNTSYSSPSASSHSNNGASSSCGTSPEPTNMQSPYNKAVDSTLTTIGEENTCSNINSAPGNNETAVFDVNGIDWFAQQNNNQFDPQLFGDYREPQNNVLSNDAFALDDGFFADAFDMPDFNSPFNVPSPMTTKKDLVQQIDEKQNADDEVVPAEDRSTMLSCNTIWDRLQKCPKVKEGDFDLDNLCKDLQKKAKCSETGAVVNESDFQNIMKNYIPKGFDSSNSTAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZP9</accession>
    <name>A0A5N6JZP9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZP9"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="134" mass="14816" checksum="E327FF3437E984F3" modified="2020-04-22" version="1">MLIEQNITPSLHNATCGSTKWHPGFQREPFISSRQISLDPIAHQIAYKKPSSLPLNRARRKAKAKAKPRQEETGQPLLVVQAAGNRSGTLNREGGGFQVSRLDPGSLLDKPNHEAGEIESSGWCMLRWTIHGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZU5</accession>
    <name>A0A5N6JZU5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DUF726 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_006860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMCO4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8294902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZU5"/>
    <dbReference type="OrthoDB" id="277931at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007941">
        <property type="entry name" value="DUF726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920:SF22">
        <property type="entry name" value="DUF726 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G12860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05277">
        <property type="entry name" value="DUF726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="62"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="627"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="84"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="631"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8294902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="677" mass="73951" checksum="BAC08E34E69E1C84" modified="2020-04-22" version="1">MAPWSSKPASTQDNDHYLSAMLEIEERIDLTLLIADITEVMQKQINDNFDASITTGEVPDKILEVGDKNPNTDGSDLNEEPGEEEKVRKSREKREKELSAPKMVELKHDTLKFFQEWQETVISRIGAVVNNPKEVTEQQKKKASAKSTPDAPPQTKVVRKTTNVVGADAVLIELYPPTSTGLYSLSEEKRVMLLHAMLLLILSLENYTAHSRILLLHIASSLHLPLHVLAETEVKVAQGLLEAAKKMSGNEETQKRSEENKVARRWKVGLAGIAGAAIVGVTGGLAAPLVAGALGTIMGGLGLGATAAAGLLGAVAQSGVIVGSLFGAYGASMTGKMMDAYAKEVSDFAFLPLRGTPHQKSVKEMAAKDRRLRVTIGVSGWLTQKEDVITPWRVLGHQSEVFALRYELEALSKLGTSLESVVKSAAWSIAKKEIIARTIFASLMTALWPIGLLKISKVIDNPFSVAKSRADKAGLVLADALINRAQGERPVTLIGYSLGARLVYSCLMSLAERRAFGLVESAVLIGAPAPSDATAWRSMRSVVSGRLVNVYSENDYILAFLYRTSSIQFGVAGLQEAQDVKGIENVNVSEMVSGHLRYQYLVGTILEKIGFEDIDIEEVAKEEETLELLDEQEKKEEDKGKAENLDPEVEARNMERDVQRRTDETMMQHGAEKLHVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZV1</accession>
    <name>A0A5N6JZV1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZV1"/>
    <dbReference type="OrthoDB" id="18472at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="88" mass="9841" checksum="FF35C06A1604AE9F" modified="2020-04-22" version="1">MDISTLPKLTGTLFVHSVLHSNEADMAKYKEVHDKQTALENMADREDAMSKSLFVGFTFRHRKPNTDDDGKVSPRKAIPTDGTFGTML</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZV5</accession>
    <name>A0A5N6JZV5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8294912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZV5"/>
    <dbReference type="OrthoDB" id="3485019at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8294912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="649" mass="73461" checksum="8E67B07346C5D16E" modified="2020-04-22" version="1">MNKRSREPSGRSEPYGYPSASIPAPASATTSEFQGLGQQDINNTIEPWIYDIDCNFPNVGYVAPPPEVNLGSQYESVTLRTSRDPNGLERSSVGEESLLDLLEGSQKLEKPSHLTHKANPKQLPEALKYLAPAPPQNIVSHQSGNTQSRLAHQPTPQEVLPLRQNPQDTNHSQRQVSNVQSIPYLPSATHPTTLGNVNDPFMYGSVDVLSQPLEIAIGPMPPASFSKGKAKRKQPQKPNVDHLISGFCDSCIRVSNFNVAPSTQGTRTENLESLVLYLLPSHMEENLRAIPRNTLKTKTWRIFSAERAERAFDHDFDNVVFSDHFVLAQEQARSTGVFDEKYSDLMSIAQTYQESILQPNKSLEASCRILIECCELYKCFITTTMPPPPIPVLNLLEKIRTTRSTMRRAFKEYQALALAPSDFRSRRDWLPSFLSACSLAISAVVFIDMMVAIPSPYRERIWGVTWQGRITEIRHGGYGMMLEVLRANTKNVNPLELSCWNQGLDTNFQALNNNTQDPFAGNQFINAQYSTGYTFDPSSHPQNSYNLATLTPDFNQDILYANMKYDQTYYNNWQQTQIQMQQKAKAEEERRILLGDNSPEALQGMMAVKSWQRRNYEHLKLGENIFKKDLYRQATINPIAGLWRIFDMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZW0</accession>
    <name>A0A5N6JZW0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZW0"/>
    <dbReference type="OrthoDB" id="3941926at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="174" mass="19925" checksum="C1AD9869FE470241" modified="2020-04-22" version="1">MVQPGYQQYMNLGNTAVAGQTLQAPQLTATDPTIWQVQNHTSAPAFISTHFGRYEKRDMVADHKVTPILRSNVAAGVSAKATSLRQAYPELIRHIKKPTFWDDLYFLWDAADIQLEGPEFLYYVMHRLGAENEQLDREYEEAQNNEVDEYARTWVTNHRELVLNSVAGMEINPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZX3</accession>
    <name>A0A5N6JZX3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZX3"/>
    <dbReference type="OrthoDB" id="4072826at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="161"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="347" mass="39733" checksum="837A9B8259B17096" modified="2020-04-22" version="1">MSQYAAQSDRLWLEPLVAEKHLDDYHEMMSDPRVESWTKPTESIAESKAYMAERTPNPEKPWIENYAILLRPLSLAPVNEKPKLIGALGMIRFEAGHGAEVGYGLHPFYHGKGYATEAMKLFLGLYWSKDREGDWNTLVAAIDPDNIASQRVVEKIVKTDRLLLEPLNLNKHLYSCHEILSDLRIAKWSTRGPNINIEQTKDRILESMSSVQFRMWAIMIPSASSTLVDVEDYSEENDMKMIGIIGTSHTPANVGYKIHPNRWGKGYMTEALKLFVEMFWTLEEKKAFPQIVAAYTPGNHASARVLEKVGFNNGQLLREELELWSNRGLNRKSDIQCMYIDRPQFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1C8</accession>
    <name>A0A5N6K1C8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8295967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1C8"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="109" mass="12857" checksum="6421E00E44EBCB72" modified="2020-04-22" version="1">MALGVFTNFFFFFFFFFFFFFFASGVLLRLQGCKLAGLQELMLVTYDARKRGDGKGVGTFRHSSGHLHGRKLLCNGWHIKFKAMCLARHTLSQRWAFLAFKEWNYFLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1D0</accession>
    <name>A0A5N6K1D0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_008785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8295966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1D0"/>
    <dbReference type="OrthoDB" id="431169at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8295966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="110" mass="10503" checksum="A7F477046C781D59" modified="2020-04-22" version="1">MATPGPANVSGGMHGMNGAMMGGTGGAFSTANGPPPGLSAPPGLGLGRMGYAGVMTSGAMGGTPYAANTSLRGSNNWTGQGFTSAMAAGGPTPMMNGSNGGFPPAYMMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1D2</accession>
    <name>A0A5N6K1D2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_008786</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8295968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1D2"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8295968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="161" mass="18718" checksum="AFD2651EE12098AA" modified="2020-04-22" version="1">MVEWVLQFYLVLGGVFTIKRFPIRVAALVEVAAESGKEKVAFGMVLLMNFLFMALGVFTNFFFFFFFFFFFFFFASGVLLRLQGCKLAGLQELMLVTYDARKRGDGKGVGTFRHSSGHLHGRKLLCNGWHIKFKAMCLARHTLSQRWAFLAFKEWNYFLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3D4</accession>
    <name>A0A5N6K3D4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3D4"/>
    <dbReference type="OrthoDB" id="10250441at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="672"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="876" mass="95105" checksum="BEB0389F460EE537" modified="2020-04-22" version="1">MASITSPQNSNKLLDPSTSNTIAADQTEHSDDFSDEAEIMAIPHISDEDAQSIIGVSLSHAASRLKSSRTPAAEKAAAMDNLEGGYFDSDPETPPAVEPKTPGPLDDERLVEPKYTKAKGMTLGKLPSPKLSPKPDFPLKSPPSPWRAGPKQIVVAEPSNEGRGSAMASVFSTGRKRQSSLSSSADALKKLLPKGLPSMSQVGNLFSTSTSSNHKSRASIGLPRSATLSPFSASPNRSKDEGSSSTNASQVNGHLTTHYRSSHHHGNSQLQNEGSADNNTTERPRVLRRATSDDSLLYHSLSRTSSLGDDTRFENHREQVNSRVKAIRDSFQDRSTFRMPQLPNILPTATKKKSLEPSPSFAKSDTFPGNENTRSSTKPTNALDKAMEHLTGDVVIMGGYRGSILRSAKAPHHQLWVPVKVGLNIRKVDLEVGLDPEDEERMEESIFPSGMLTNIGPVDISRRLFKRLRNCENAQNGKLRVWDYGYDWRLSPHLLSRKLKAFLETLPSNQPGPNGQKPTGALVIAHSLGGLITRHVVNQRPELFSGVIYAGVPQSCVNILGPFRNGDAVLLSSRVLTAQVNFTLRTSFVLLPENGECFFDIHTREKYPVDFFNLDDWIKYRWSPVTDQPLPPILQNASGIGSILNLQMQNSLSSLTTIAGKKPGSGSGSGSGTNTPQPSSPHLGSNTRNENDDRNQSIDQSKTSRTAEVLRGMDGTDRTLAPQMGNLLNKGHNPSSSVSTVVTLPRDKAIAYLRRTLAETLQFKKELHFRPEISDANRYPPLAIIYGKSIPTVYGAKVAGREGIPCADVYDNLAFASGDGVCLAREAMLPDGYQLARGGRVRSDRGHVTLLGDLNAVGRAMEAVRKGRMKGIGLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3E2</accession>
    <name>A0A5N6K3E2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">MRH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_002244</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3E2"/>
    <dbReference type="OrthoDB" id="4504960at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.130.10:FF:000024">
        <property type="entry name" value="Putative vacuolar sorting receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028927">
        <property type="entry name" value="Man-6-P_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071:SF0">
        <property type="entry name" value="MANNOSE 6-PHOSPHATE RECEPTOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02157">
        <property type="entry name" value="Man-6-P_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025043806" description="MRH domain-containing protein" evidence="11">
        <location>
            <begin position="23"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="12">
        <location>
            <begin position="34"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8296831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="286" mass="31637" checksum="E8B565E634D96950" modified="2020-04-22" version="1">MRFTSLPSALLLGLALHIGVEGAVLEDKKPKPVDPCTISSTTGSFFDLRPLSIQPSEEGKKPAKNAKTDSWHARGYDYKGNFTLNVCAPVVEGVKDIVGVDKNHWQNVSAFYEFDGKKYSVGQQSGNLTLRGRKLVLEYMNGSPCGGKNKKRSWDDDDDDDDDDNKSIRRKSSTISFHCEKDPLASASASYVGTDPEECAYFFEVRSQAACGGSEPAKQTVGPGAVFAIIGVIAIMVYFLGGIFYQRNVAHARGWRQLPNYSFWAGIGNFIKRPLGMVRPFYRLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3G9</accession>
    <name>A0A5N6K3G9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3G9"/>
    <dbReference type="OrthoDB" id="5399555at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="128" mass="13977" checksum="9DE50528BB9695B7" modified="2020-04-22" version="1">MVASLESSRPIMAPSVSSKSNRLSTCSQAISIATTDSAREEIIAIEEGFDKLHNKKLESQRCDLTTEKRDNMGKLALGAKLERALGRRMGSQDAVMRKKSPSQSSVDSPTSTLNEKAQLYEDEKETAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5D2</accession>
    <name>A0A5N6K5D2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">40S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_002649</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5D2"/>
    <dbReference type="OrthoDB" id="1702480at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.50:FF:000002">
        <property type="entry name" value="40S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.910.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_uS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_uS13_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003140">
        <property type="entry name" value="PRK04053.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8297294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="156" mass="17905" checksum="DF95CC92471260A1" modified="2020-04-22" version="1">MTQHPALIHTLLTPQWLLNTNVEGKQKVQYALTKIKGVGRRYSNLVCKKADVDLNKRAGELTSEELERIVTIIQNPTQYKIPSWFLNRQRDIVDGKDSQVLANGVDSKLRDDLERLKKIRAHRGLRHYWGLRVRGQHSKTTGRRGRTVGVSKKKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5K5</accession>
    <name>A0A5N6K5K5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor IIA subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">General transcription factor IIA subunit 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Transcription initiation factor IIA small chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_001665</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIA subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5K5"/>
    <dbReference type="OrthoDB" id="586585at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005672">
        <property type="term" value="C:transcription factor TFIIA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10014">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10145">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.190:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.190">
        <property type="entry name" value="Transcription factor IIA gamma subunit, alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009083">
        <property type="entry name" value="TFIIA_a-hlx"/>
    </dbReference>
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        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003194">
        <property type="entry name" value="TFIIA_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015871">
        <property type="entry name" value="TFIIA_gsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015872">
        <property type="entry name" value="TFIIA_gsu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10966">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02751">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02268">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit N-terminal" evidence="10">
        <location>
            <begin position="7"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit C-terminal" evidence="11">
        <location>
            <begin position="64"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8297871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="126" mass="14503" checksum="31901C237D568B18" modified="2020-04-22" version="1">MAAPQSFYELYRRSSIGMALTDTLDDLISERRIEPQLAMKILANFDRSITEVLADKVKARLTFKGHLDTYRFCDEVWTFLIKDVTFKMENSKKGYFGRSLVFAAFYGTFPENGGSFAISLHHIMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5L6</accession>
    <name>A0A5N6K5L6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5L6"/>
    <dbReference type="OrthoDB" id="3543450at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="383" mass="42180" checksum="4DFCFF416073446E" modified="2020-04-22" version="1">MHTGTEDEDKNGKDCDVPAALQRPADDQADETEVSAEGESSEDSEQSNEEDDNGENNHNFDEDIDEQVSGGNAARISIEGLSQRRESFMEPCEGLTPDEPQITGAEREFGDYSHPSQLSISGIWKNTTTIQEAEIWRPRKPKSSGVANETSEDIFDSPSPGLDNAKRRSSTGLQLRKRRTFSSLPLSLTTSRLNATSSLKVKENLRLELEISETQFIAIREVSPELGGSHGVNHFENSMRDEFIDKDGDILPPFSQLSFVPEEVPEGSYFYRASQTLMGSSHTPKSRAKSTPGCFHPKTARQGITPAAVQSSSEHTSNLICETKIPPKFSQLSYATTPRSEKSLSSITRKASFALGTLPASVRRKRAKTLAFIPPFKKAKLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7N0</accession>
    <name>A0A5N6K7N0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7N0"/>
    <dbReference type="OrthoDB" id="2162691at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="164" mass="17943" checksum="0C56EC66189F0826" modified="2020-04-22" version="1">MVDPNHLSTQSSNFLVDSSTMDDIPASPTASESSKSNGIASVFSKSRNGKRHRDSTSHSVRSGGSEASHGFRASLEGAIDKLKRDSDSETESHGSNGLKRFVPKGFESKKKRLQREEEERRLEEVARGRDVAERGTLENDSRTPINRNLSAGSSLLTYDSESES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7N1</accession>
    <name>A0A5N6K7N1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_000972</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7N1"/>
    <dbReference type="OrthoDB" id="2134400at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF107">
        <property type="entry name" value="ANNEXIN ANXC4 (AFU_ORTHOLOGUE AFUA_3G07020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0041">Annexin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="143"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="213"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="299"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8298799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="701" mass="78008" checksum="B9797924E454AF8C" modified="2020-04-22" version="1">MSLDPRDSQRRGRSKSPGRERSRSRSGYGQEVVRAPTPPGYDADGGDRREYEYDESRTGRTGFGASRYGDGTGTGIPDTLKIDEVKYTERDRDNERLHTPAQFDTLAYGEGYEPGTPAKINVYGSRDPSPAAVPRSAAYGKDVHTPTYSTYSDRLASPRDHEYERDTRRHEGEHHGRQRSASFNIAAGLGKHHGSLSAGVSVAHDKTYPQSAVGSQFSPVSSPGLPGARFGTPASPTTGGGWASSGYGNRDEEHGRRPESPQYQYGQSGEKIKFSSTTRKTVISGGEYSEERSPSLPLRIHRRRDSSPPPRHHRLESSSARSSSSRLVTEQVISVNPGSRRDASPNPSRLGDRLNTLSINTSGHVGGHSSHGSLSLSPGGHSHSGSLSLANAPGSPLLETYKGTYQSISPMPSPMLVVTAHSDISENFSPLSPSGEDRSFRRTARFHDSLDEAEIIRDALKGENHAPDVQPLITILPGLTHEQILDLRAEYKKIVKTGHERKGVNIAKHIKLRLKDEDPNLMKACYAVALGRWESEAYWANFWYQGEKSRRELLIESLMGRSNREIQKIQDGFSDKKYRDSLRQCMDKELKEDKFKKAVLLVLDEKKMEESRRIDGELLREDIRQLEKCVTSEKGGESRMIDIVCTRSDTHLREVLRGYEERYGKNFAREMLRKSTNLVVCFIPVFPLYCHIPSTNTESPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K801</accession>
    <name>A0A5N6K801_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K801"/>
    <dbReference type="OrthoDB" id="3468131at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8298844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="123" mass="13579" checksum="EC7825CF6E7DAFFD" modified="2020-04-22" version="1">MSIVNTYSRLILITQYWSYVTLATLREAEQHWIKNRSDLTLSAVEGVDIPNAMNYVTGGDKSGDIFGVVVAIDKTSDEGYVQLMNGKLIPTGPNEDGYECIIIPADQGFVTYGSSAVLYVHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K804</accession>
    <name>A0A5N6K804_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SMODS and SLOG-associating 2TM effector domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K804"/>
    <dbReference type="OrthoDB" id="4472872at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041622">
        <property type="entry name" value="SLATT_fungi"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033635">
        <property type="entry name" value="SLATT_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38793">
        <property type="entry name" value="SLATT_FUNGAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38793:SF3">
        <property type="entry name" value="SMODS AND SLOG-ASSOCIATING 2TM EFFECTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18142">
        <property type="entry name" value="SLATT_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMODS and SLOG-associating 2TM effector" evidence="2">
        <location>
            <begin position="69"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8298905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="252" mass="27441" checksum="993870112ECD92BE" modified="2020-04-22" version="1">MSAESTPLLSEPIPSHHPLSSFSTLSRSPALQKFRLAIGINVPIALPATTPPSDLEALRRNAYGIYKSVLTQQSKFSLQYHLIEAIYYSSLLSQLVIGGVLASFGELSQTHPKAVTTLGVLNSCLAGVLGILKSQGLPDRLRKDEFEMRKVQDFIEECDTRLAVGWGEQISETEVDDLIKDVFDRYGVARDTTEMNRPNIYAHQADADEDGDSGSNKGQGRMQGGTMNARTLIGGRQSKISLGGNGKALQIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K810</accession>
    <name>A0A5N6K810_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K810"/>
    <dbReference type="OrthoDB" id="3547739at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8298929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="109" mass="12731" checksum="934ECB250A5134C5" modified="2020-04-22" version="1">MKILQETERRVNESRLYDMPNYEKVKNSQQLAHGCQKTGQRGELIPFLLFQPMVLVRQPGSIKSESDINVDLKEDFSFQINSNKRRTQGYIQKTPHPVPNRIIHSVYDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9P8</accession>
    <name>A0A5N6K9P8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_000163</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8299920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9P8"/>
    <dbReference type="OrthoDB" id="73846at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050838">
        <property type="entry name" value="Ketopantoate_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765:SF2">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="104"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8299920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="136" mass="15533" checksum="86BDFDCFAAE0FD19" modified="2020-04-22" version="1">MWKCVEAGYDTNIDLDNGWIIKYGRGMTPTHEKYAKIVKKKASESARTIAANKEESAKAKARLRVAKDLAAKRLEEKEKRRELLDAEHMVRRGFKRFVFGETVEAPLSPPDKTYFKPKGPTEAPSIWGELEAPRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9Q3</accession>
    <name>A0A5N6K9Q3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Wings apart-like protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_000130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WAPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8299885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9Q3"/>
    <dbReference type="OrthoDB" id="78088at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039874">
        <property type="entry name" value="WAPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022771">
        <property type="entry name" value="WAPL_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100:SF13">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07814">
        <property type="entry name" value="WAPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Wings apart-like protein C-terminal" evidence="3">
        <location>
            <begin position="145"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="13"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8299885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="615" mass="68905" checksum="B2A44693AD3068BB" modified="2020-04-22" version="1">MVAFRKPLSITPRKRLIDSLVEQTPHQDSDEENDNDSEDEHNSSQVEDHFQHLNHSRAHSLTPEIPTFTTSQVSQGSQVAGPKFTYSRQRSMLVEEDTMQQLAFDMPLEVPQGSHRRLDSIPPLKPLLSFREEEEEEDEAASTTIRTIHELRQAGANSRFADEVEDLLDRIGKPVAKPSSMRRSGLLDLGIKMKDKAFLRQLRAHGVEQRLFANVGQEIDTVSGFLITSLIAPILAEGSVPLVVSQLQQHDIAKLLDRLISVEKSIVSVAKERKTNMSKMAQNSLSAYHDSLLKLPTWKDLSPRELSPRTLALKCLELMVRQTREAGDASDIISEELNISLFEILKSSDGGASWDLPNGTEAINFYLTLSALESHSLVSRTAQDETAWIRQFLPVIGKTLNIALNRPLGSFGEQQILALKLTVNVTNHNPKACDAIASSDLMFTILRVIVARFKNMSNLWAEEEIVMAVDNLILLIGAMINFALWSTKALKNIDNFAGMVKDPLDELIRLFVDSREKTFEVDSQHESHKNVPFGYLSVLLGHFCLLPAIEKRIRMGQKTKTLHPLITSINEFIVYHKAADDEIAPNEDGHSPHVTVTKQLEDLVKKLITIKGTDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9S6</accession>
    <name>A0A5N6K9S6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8299884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9S6"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="145" mass="17177" checksum="E14F7C25E0FCD6E3" modified="2020-04-22" version="1">MRWTCIARYRLATPEILIWSQVELIFHIRGLQVGKGKLNYLVPVFLAPPTPTLPFPRVRINKIKNKNKIKIKIKIKNKNKNKNKNKNKNKNKNKNKNKNKNKNKNKNKNKNKNKNQQNIGSSPITSLAFYSLNYNYSYSYNYNQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBB3</accession>
    <name>A0A5N6KBB3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_000296</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBB3"/>
    <dbReference type="OrthoDB" id="4451586at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052761">
        <property type="entry name" value="Fungal_Detox/Toxin_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425:SF2">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="74"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="115"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="696"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8300059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="832" mass="92421" checksum="E599A7C0CEADEF0B" modified="2020-04-22" version="1">MDPSSLDLLRSAVNGDEQPSSSIGDIASSSEAQLPPKQSLPQTQSPGTNPKKRKPSDGNGESTNPEKKKRSSIACTNCRSRKVRCDVERSERVNEAGERVCNNCGIDGIQCLVPGSKRRRSKRSSTDTAQPAPLQVYTDGAVNPQHISNDDIRRLSGASTANSPRNLPPYVPQHVPHSIYQSAIHAKESTGIDGQRLAQLTHSASMTGDLVRTRLASSPPPSLKHSLPAYINPLPPKMTSSDIDYLWAKSALRIPSLSLRNALLRSFIEYVYPYMPLLELHKVLQIINDEGGSGSMSLLLFQSIMFSGTAFVDVKILSDAGYSSRKAARKSFFQSARVLYDLDYETDMLTVVQSLLLMTYWYETPEDYKDTWHWMGRAIDHAYTLALHRDPKGMDVDHKLRKRVWWSCFMRDRLIALGMRRPTRVKDEDCDVPMLTEDDFEIKALDPRNSIISSECSLIRDVDAQRDLALMCISKAQLCLCISQVLVAQYSVLARHQGVSSEIPSTTSSIMLFPKKSESSDEVERCDLALDHWKDNLPQACIYSNQLKVGNSGRPLFVACSLLHMIYYTTTSALHRPRVLPVGPNHQQPETLFELSREVVTKAAQGTTKIIDDMHRLDLERYLPTTGVTALLPAIIIHLLLVRSPYQSERQPAIDGFCLCMTVLEGLKDNYASADYATQFLEAAVRKAGMEDIIGRARAAARREDAKRKADLARAELERMQRSMAERITPPADTHLNGFEPLGALVDNSTAVYNGILAHSPPDSDAILGGAGSALPPDPNDMFEFLNMNYNEGGESAGYYDMDLFTKEIPGFGSRMPSPQPGDILFSQEYMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBC0</accession>
    <name>A0A5N6KBC0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000653</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBC0"/>
    <dbReference type="OrthoDB" id="2110361at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024895618" evidence="2">
        <location>
            <begin position="19"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="256" mass="26905" checksum="0B44ECE005112A1A" modified="2020-04-22" version="1">MHIWRCTLFLLFGGHFDAAITCIRAAAIIGYSREVNVACGRHIAFFLSTLIEKKRSSSMKGREAPGYLGQRIGRYEMDEEVLAYLSGDLQGGDEAWIWQGRDVMGMRSPGVSAGSSSTGGSPTLSREGDRDREMRGLSGVTGSGGNLLVLSEAEARDWGGWERVQYLVDVFARESSASGPVPTLGIGGAGTSASGGYNTEPRGVFGLGVGVGPGVGGGLGVSGGDVPGTKPQTSPLTVRRDDRSRGSERMSITNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBD3</accession>
    <name>A0A5N6KBD3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBD3"/>
    <dbReference type="OrthoDB" id="3480289at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF1">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="11"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="347" mass="40080" checksum="5BDC8708007FF72B" modified="2020-04-22" version="1">MEYDMFSKDVFHKFPELAPELQDMIWDFATKVERTIEVHLWKRCAEWMIVYASTDVKNPAILSVCKAARGRGLRKYKVLTVDNSWRRDKTMYDNNQERQGLPLNFVGPEAAATKFKCYINYDRDTIFINTEHSLANEDAFPSGTETWREAFGYQFLKDLYFSSAGEKLKSLAIDYRVAEKWLNSDRDNWQYCQVFACMSKLSNLAVVWTDHKGLEHLIDKECCTTKLITFEDTAKPLSHEDRYGAKFPCQGVHRRVKNLKEISISAGDSGDNCAFEKFASGKTSTTWKENIMSAIRDNRPHNPVGSDPFHFVNGKSRYRDLDDLDISQVCVEREESEADTQEACCDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBE1</accession>
    <name>A0A5N6KBE1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_000646</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBE1"/>
    <dbReference type="OrthoDB" id="10263513at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.63.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.63.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004977">
        <property type="entry name" value="Ribosomal_eS25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12850">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03297">
        <property type="entry name" value="Ribosomal_S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8300478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="149" mass="17060" checksum="AF7F3C0652A940BA" modified="2020-04-22" version="1">MEWHAMAWHKYSAFFARHTQALKFENPSTSVELISKRSIHSSRQHQTDKMAPANTGAKKQKKKWSKGKVKDKAQHAVILDKSTSDRLAKDVQSYRLVTVAVLVDRLKINGSLARRCLKELEEKGQIKIVVKHHAGDIYKLWIHFMVGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBE3</accession>
    <name>A0A5N6KBE3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBE3"/>
    <dbReference type="OrthoDB" id="3565259at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="341" mass="38838" checksum="D6C1B4519F2BE150" modified="2020-04-22" version="1">MDQPTDERQYPSYPSHTPGNTMMRFCIRDRKWKPKSDFPHDPARPGHILLSKRGEPIKFCTRCTDYINQRALEKKGLAVRRPANPSSRRRKVKTTVGAARFLNQRLKENIRQRRRLDREAEENLEERRLLLAEMARLEGRGDLPEEKDDDREVGGGGSESEGDNHDDDDDDDDDDDDDDDDDYENDDDHENDEDTRLPNIHKTDTYHMSKQTPPLATTTAAATTTHQPSHPNNHHHTTTYTYPAPPTNAQPNPYPSSHDSYPSEPYGASPHDQHPTTLSFETGTYRSLTPPAQRAARFALQGSLYGVLGSPGTNGTRYLEEGADGWETWEEQEAMFGRRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBE9</accession>
    <name>A0A5N6KBE9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_000691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBE9"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8300530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="116" mass="13214" checksum="9BA6898FFB5749B2" modified="2020-04-22" version="1">MLDLIHHQQSLAHKLHYNLPTIQKLTSPNPHPTAAWEFTGANNLVPHNFDLSSIAPLQPMHDLIFNDLSTNLGANYDLQYQGFPDANIYAQQPEPWQFEGDLGQDSFWAVMNNYNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDB5</accession>
    <name>A0A5N6KDB5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcium-binding protein NCS-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_003233</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the recoverin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDB5"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000009">
        <property type="entry name" value="Visinin-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF178">
        <property type="entry name" value="NEUROCALCIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="159"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="195"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="243"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00071944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8301355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="351" mass="38854" checksum="32A0056F1B427F4E" modified="2020-04-22" version="1">MHSASLATGQAKVNLNNNSRNRDPPGQPSKNGRSYSYLGQFIPHGVSTNLLNSQPQPQPQPPPATPSILPHTISQTKPLVGHSESASRAALLLAPNIYKMGKSQSKLSAEQITELQKSTHFDKKELQQWYKGFLKDCPTGMLTKEEFQKIYRQFFPFGDPSSFADYVFNVFDSDKSGSIDFKEFICALSVTSRGKMEDKLDWAFQLYDIDGDGKISYEEMLAIVEAIYKMVGSMVKLPPDEDTPEKRVKKIFRMMDKDENGSLDMEEFKEGSKRDETIVSALSLYDGLISESRPGGPPGPPSMYFGSFVPPSSPIMGGLCFWKEVFVDSLSVAYGTGKLSPGLDPKDGSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDF1</accession>
    <name>A0A5N6KDF1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">KRR1 small subunit processome component second KH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDF1"/>
    <dbReference type="OrthoDB" id="441223at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048548">
        <property type="entry name" value="KRR1-like_KH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024166">
        <property type="entry name" value="rRNA_assembly_KRR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581">
        <property type="entry name" value="HIV-1 REV BINDING PROTEIN 2, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581:SF0">
        <property type="entry name" value="KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21800">
        <property type="entry name" value="KH_KRR1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KRR1 small subunit processome component second KH" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8301404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="177" mass="20949" checksum="974A36E7641A11BC" modified="2020-04-22" version="1">MGPYKGLKEIRRIIEDCMANIHPIYHIKELMIKRELAKDPELAGESWDRFLPQFKKRNLSKRRVPRNVTDKAKKVYTPFPPPQEKSKVDLQIESGEYFLGKQAKERKAQEERIEKQKEEKDEKMRKRAEEYEAPAEDGEKKEKKRKRDKDSGEKKEKKKSKKRKSSDADGDVDMAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDF5</accession>
    <name>A0A5N6KDF5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDF5"/>
    <dbReference type="OrthoDB" id="3561891at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="169" mass="19121" checksum="BE1C1007DBAACFC8" modified="2020-04-22" version="1">MAWPKVLFDMNAQAPKHLAGGDLFEIDPWPIRRYTILSIKRVYRPRHSVSRPPIVGVDTGPREGGVDLQRMRVGFVLNDEQPKPEAIVPENKNPQPQPQPQLQDPRPRPRLRGHPYGLQLPSLRQVLNSPNDYPQPIIDRNTRVVQLRLPPADGRNSLPDAPARPAPDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDF9</accession>
    <name>A0A5N6KDF9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_003356</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDF9"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="4">
        <location>
            <begin position="2"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Ketoreductase" evidence="3">
        <location>
            <begin position="136"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8301503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="34609" checksum="9DC4655E10D623A4" modified="2020-04-22" version="1">MGIVDNYIGDGNGLGRIFNSRNSSFLPEIMREANGYGLDVVLNSLSGDLLHASWKCLAEFGKMLENGKRDFIGQGQLPMDPFEANRTFYGVDLTLYVDRRPLVINSLLERAMEWCSQGAIQPIKPVKYFEAHQAEDVLRGMQSGQHIGKLVMVDHGARKFIYLSRSGGKGKDDAALVDELREARCTAQIIAGSVVNKADVQKAIAQAKYPIAGILQMSMVLKDASFPNMTYEEWQDAILPKIQGTWSLHEAFASQSLDFFVLFSSFAGLIGHWGQATYASANTFLDAFAQFRHSKGLLASVLDISIIGDVGWVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDI2</accession>
    <name>A0A5N6KDI2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thiamine thiazole synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Thiazole biosynthetic enzyme</fullName>
            <ecNumber evidence="6">2.4.2.60</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_003334</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[ADP-thiazole synthase]-L-cysteine + glycine + NAD(+) = [ADP-thiazole synthase]-dehydroalanine + ADP-5-ethyl-4-methylthiazole-2-carboxylate + nicotinamide + 3 H2O + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:55708"/>
            <dbReference type="Rhea" id="RHEA-COMP:14264"/>
            <dbReference type="Rhea" id="RHEA-COMP:14265"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:90873"/>
            <dbReference type="ChEBI" id="CHEBI:139151"/>
            <dbReference type="EC" id="2.4.2.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homooctamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">During the catalytic reaction, a sulfide is transferred from Cys-217 to a reaction intermediate, generating a dehydroalanine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the THI4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.60" evidence="6"/>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDI2"/>
    <dbReference type="OrthoDB" id="410463at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160205">
        <property type="term" value="F:cysteine-dependent adenosine diphosphate thiazole synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052837">
        <property type="term" value="P:thiazole biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03158">
        <property type="entry name" value="THI4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027495">
        <property type="entry name" value="Sti35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002922">
        <property type="entry name" value="Thi4_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00292">
        <property type="entry name" value="sulfide-dependent adenosine diphosphate thiazole synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43422">
        <property type="entry name" value="THIAMINE THIAZOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43422:SF3">
        <property type="entry name" value="THIAMINE THIAZOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01946">
        <property type="entry name" value="Thi4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="110"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="296"/>
            <end position="298"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="2,3-didehydroalanine (Cys)" evidence="6">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8301476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="318" mass="34452" checksum="A3C1260CDEEDA7DD" modified="2020-04-22" version="1">MAPPSAMFPEATSPIDGVQLKTGFDVKVAPAQAATQGKTLADLAEKWDQGFTFAPIRESQVSRAMTRRYFNDLDTYAESDIVIVGAGSCGLSTAYMLGKARPDLKIAVIEASVSPGGGAWLGGQLFSAMVMRKPADAFLTDLGVPFEDEGDFVVVKHAALFTSTLLSKVLTFPNIKLFNATSVEDLITRQDDDGNIRIAGVVTNWTLVTMHHDDQSCMDPNTINAPIVISTTGHDGPFGAFCVKRLVSMNQIKELGGMRGLDMNVAEDAIVKRTREIVPGLIVGGMELSEVDGANRMLYRVPHLVPWHFLVSRPRKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFJ8</accession>
    <name>A0A5N6KFJ8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005878</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFJ8"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF24">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="27181" checksum="BC74F91628BC775E" modified="2020-04-22" version="1">MSPTIILIRHAQALHNVSHKARNYQLHDPALTDLGFGTQCDELARFLENDVPLAQKIDLIVVSPMRRTLQTAQQGLGWLIKRGVPVILRPEWQENSDKPCDTGTPIELMAKEWPQFDWSTVDPLFPEKSGIYGYSKAALTERGITARKWLQQRPEKVIAVVSHSAFLRTCISYRHYANADYRIFDFADGDGQTNAELVEWEVTESRGGGLGKSPKGVFGMTINDYPKEIVEDIGEATSEVPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFK0</accession>
    <name>A0A5N6KFK0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_005848</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFK0"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000299">
        <property type="entry name" value="Carboxylic ester hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF6">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="45"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="124"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="214"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="168"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8302438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="950" mass="105142" checksum="55529F349BEF8BFF" modified="2020-04-22" version="1">MRAPSTTTPDVVVLSFLDEEKKIKEVADPKKDLWVSSLDGRYSSPMIPIRVGAHAQTFYVHRDILTKSEYFRKALDGEFKEAAAQAIDLPEEDPTLFEFVIAFLYESKYSPLRPVAEIIVVEPEKGKGREHDDDGNASGSDDGTDSGTASDESARSRRRRESRRRRQDRAWEQRQRKEPGRHRPDCNCASCTLESFGPTCWNCGVTRRIPPPRNRWINGMPPPPQPMQVVGRNGYPQPPGPRDRRRGSRNNTVDEPPAEERMSQEDLRTWSIAYSISVDVYVCAERYLMQDFKSCVAAFIVNNFEVAGSDAALPSVLNSCKTLYDGVSSMDPLLKKVFARVGFLQARLWKRYPEETSSFFLDNPELSTLILKEMAERREEDVKDDLPAMDRPPLPSSPREDMIIQDYRRHLPQRWAPQPPLPITNGTYNSTQTFPACPQKGTVGSEDCLYLSLYSRPWTTGQPSRPVMVVFFGGGFIQGGGSQAVPPSAYPILNVSSQNDILFVYPNYRVNTFGFLPGKEIAEDEYSDLNPGLLDQRAVLEWVNKYIEQFGGDRDNVGIWGQSAGAGSVVAQVLATSEEVTSSLFNRALASSPFWPKTYNYDAPQAQAIYNTMTNLTNCNGAINGTLQCLKSLDWKVLAEAALVVAASHTWNTSSYTWAPVIDGRFLKRTLSEATVNAVGGNGGRGQIKILGGWGENFVPSALQNATDTGTPPFNSTTASFNNWLSGFLPSFSPSQLDAIRATYPESGTAEEFPTYNTSYARAGLIYRDSVLACPALWISRAASEAGWLGEYTISPAKHGSDTIYWNQVNAVQKSQPAIYQGYAGALASFMATGDPNAHKMANATQPGVPALTSDTQFVVASAGLENVAIDGGEQSLEKRCRVSITPNFLHSCTRFSRLSVHIRGTPDLHLVFHHFESYPSFFVLACDYPSSPASSSYLSSPRITSRKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFL8</accession>
    <name>A0A5N6KFL8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_005940</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFL8"/>
    <dbReference type="OrthoDB" id="298012at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333">
        <property type="entry name" value="2-HACID_DH_C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="44"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8302554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="187" mass="20270" checksum="9823B0F238143B48" modified="2020-04-22" version="1">MGMDVIAYTASPRPTPESRKDTGKYIVPNTGDPDGLIPSAWYSGLDKASLHNFLSQDIDILLIAVPLTPQTRHFLSAAEFEILGSKTNAFIVNIARGGLINQEDLITYLKKPISAGGLRGAALDVTDPEPLPADSELWALENVAITPHVSGLGITYAERSFAILDENLGNLERGRDLINLVNRKKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFM0</accession>
    <name>A0A5N6KFM0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_005958</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFM0"/>
    <dbReference type="OrthoDB" id="48317at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="4">
        <location>
            <begin position="95"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8302576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="443" mass="48234" checksum="68D87734E1A46007" modified="2020-04-22" version="1">MSNPCSREGQSDVKQRSSGQTKLHPASKCHLQSAMVKPKDLISPLNELKAFFFGCDDYQSCFAECRHLVYQSLLTPLLKSFSSKQKSPIVVQKPGEAIAAEASIPKLRDDYILVNTKAVALNPTDWKHIEWLTSNGARIGCDYAGVVEEVGSAVTKDFKKGDRVCGFCHGGNEVNHEDGAFGNYITLKGDAQIKIPDNLSFEQASTLGVGITTVGQGLYQSLKLPLPTNPSPTKFPVLIYGGSTATGALAIQFAKLSGLQVITTCSPRNFAYVESLGADKAFDYNSPTCSQDIKEYTKDSIKHAFDCVSEASSPQITVSAISSAGGVYSTLLPVSTEDVHKINEKVENKATLGYTAVGEFFKFGPADFPAKPEDFEFAKKFWEISKGLLAERKVKVHNIAVNKYGEGFEGILNGLQAMKEGKVSGEKLVYTLKYQCNHRFICT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHQ1</accession>
    <name>A0A5N6KHQ1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCAAT-binding factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_004750</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHQ1"/>
    <dbReference type="OrthoDB" id="10263185at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030692">
        <property type="term" value="C:Noc4p-Nop14p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027193">
        <property type="entry name" value="Noc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455:SF0">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="3">
        <location>
            <begin position="317"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="CCAAT-binding factor" evidence="3">
        <location>
            <begin position="350"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8303310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="519" mass="59125" checksum="50EBD3939BAB74CC" modified="2020-04-22" version="1">MPGKILDTKRASKRKRDVSEKGPSKRARSESSEEDSQAQILLLESEIFESKKNYNNIARLIGIARDDSEGADASILAAISLCRVFTKLIVVGGFQKTKDTSVKDATVIQWLKERYSEYKIVLLDMLSQEDAASTALTLCMRMLKIEGQHMRNGQDYCFPIGLLTDMIQVLIRPGSDSSVRKEFSEKFVEEYDDVRFYTLEAIQKLVTTPKDQHLECDSFDAVYEVLTSISSVPESKDELEDFYIPAPKKKAHALYSLTEHKKRAQGAWLAVMNMEMVKERRKLILSKITESIAPWFTKPELLMDFLTDSYNSGGSTSLLSLSGVFYLIQEKNLDYPSFYRKLYSLLDTVVLVASFIKRLSRLTLHSPPSGVVAVVPWIYNLLKKHPTCLFMIHRETRGAEAKKVLEEEGLSDPFLMDEEDPMLTNAIDSSLWEIVTLQSHYHPNVATLAKIISEQFTKQSYNLEDFLDHSYGSMLESELAKDVKKVPVVEYEIPKKIFMKHDVEAGLEDSLLVKLWSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI08</accession>
    <name>A0A5N6KI08_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI08"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="76" mass="8923" checksum="23C7747B766C413A" modified="2020-04-22" version="1">MCTQNEEMMFDQYRLLSDFLSSHIYYWAAISRHGIEAFASIGLHNVDHFSKTSVHKRSPPTHACHTRSHANRKYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI12</accession>
    <name>A0A5N6KI12_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome c oxidase subunit 6, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cytochrome c oxidase polypeptide VI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_004761</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Peripheral membrane protein</topology>
            <orientation evidence="1 11">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the cytochrome c oxidase subunit 5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI12"/>
    <dbReference type="OrthoDB" id="5778907at2759"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.40">
        <property type="entry name" value="Cytochrome c oxidase, subunit Va/VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003204">
        <property type="entry name" value="Cyt_c_oxidase_su5A/6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036545">
        <property type="entry name" value="Cyt_c_oxidase_su5A/6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14200">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14200:SF11">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02284">
        <property type="entry name" value="COX5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48479">
        <property type="entry name" value="Cytochrome c oxidase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 11" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8303325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="183" mass="20705" checksum="C861BFCCBE4BD1DC" modified="2020-04-22" version="1">MRFIHFSPQQPIGYAEGLLETKQVGIRAPISVQTTKSRETSPHQLFLMSSTRILRIASRAQPSAIFRSNGLRSFTPRVAPTMSATSANCFSTTSRSLSADKDGQEAAHHEESFEEFTARYEKEFEQVQDVFELQRNLNNAFAYDLVPSPSVVLYGSLRVSRQRLRIVANTINIWRNLSHSVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI18</accession>
    <name>A0A5N6KI18_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI18"/>
    <dbReference type="OrthoDB" id="506498at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="35850" checksum="BD50ADA7C7AE5A88" modified="2020-04-22" version="1">MASHPESQTIEVDNTYFETVTYHNRDFQQYAITNLSYFQPIDEDELERLHVWNAVLNRVFDNRLLFPTLNRPRRILDCGYGTASWAIDVATQNPGCEVIAIDIYPFQPETVPANLYLQVDDLNNRFTFQAHNFDLVHSRLMAAAIHVNRWAGYLRDMFRVIRPGGWCQLVELYHNAQSDNGSLTDAHALRQWSTRYLESLNGVKDLRIAARLPDMMRAAGFVDIEHRMIPLHTCGWSSDPREYDIGTANRENVQQFLGSIAVYPFTERLGMPIQDVQLLVAQARREADDPALKVYFPLYVCIGRKPRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI27</accession>
    <name>A0A5N6KI27_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein uL4 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_004756</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI27"/>
    <dbReference type="OrthoDB" id="10259785at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025755">
        <property type="entry name" value="Ribos_uL4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013000">
        <property type="entry name" value="Ribosomal_uL4_euk/arc_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045240">
        <property type="entry name" value="Ribosomal_uL4_euk/arch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19431">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14374">
        <property type="entry name" value="Ribos_L4_asso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00939">
        <property type="entry name" value="RIBOSOMAL_L1E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL4 C-terminal" evidence="5">
        <location>
            <begin position="280"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8303318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="373" mass="40065" checksum="F6F2D3D234A186D7" modified="2020-04-22" version="1">MASRPTVSVLSADGKATGATIPLPKVFTSPIRPDIVQTVHTGMAKNKRQPYAVSEKAGHQTSAESWGTGRAVARIPRVSGGGTHRAGQAAFGNMCRSGRMFAPTKVWRKWHQKINLGQKRFATVSALAASGVPALLFARGHQISEVAEVPLVINSEVFEGAKIARTSAAAGLLKTVGALADVEKVKGSRKLRAGKGKLRGRRHRQRRGPLVIYDAKVDGKELVRGFRNLPGVETSDVYALNLLQLAPGGHLGRFIIWTSSAFKALDEIYGTTTAPSALKKDFLLPSNVVSQADIGRLINSTELQSVIRAAKGSALTKRAGVQKKNPLVNKQVLLRLNPYAAAYSKEKIGTKGLDAGKPERINKTQYAQVLKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJN1</accession>
    <name>A0A5N6KJN1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_005246</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ARS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJN1"/>
    <dbReference type="OrthoDB" id="342064at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025239">
        <property type="entry name" value="DUF4187"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039727">
        <property type="entry name" value="SE/Ars2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007042">
        <property type="entry name" value="SERRATE/Ars2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165">
        <property type="entry name" value="ARSENITE-RESISTANCE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165:SF0">
        <property type="entry name" value="SERRATE RNA EFFECTOR MOLECULE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04959">
        <property type="entry name" value="ARS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13821">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01173">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="256"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8303878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="427" mass="48013" checksum="5CBD396D68E58DB5" modified="2020-04-22" version="1">MVEYLRRVFNFCFFCVFESDSIHELTRKCPGGHLRRPRNTLTTSAKAAARASALGDPFPGKKPIEDKMDLDPLSPDGERKFPRNTVSKSEQQLQRAFNWVRTFEEKIMQILDPDNVDVRRLGGRPTEDALKEELVKYVKQEDDHKFRCRVPECTKLFKEEHFWKKHVEKRHPEWLESIKTDFDLVNTYVLDPAHIAPSRSDANSNGHFPPANGHMPAGTPRGFNLQNFGLNGLNTMQGFPPPTGFPPFLAGHAVQSPMGWSGGSENRGPGPIRRGAGRYQNNNRTGPYDRRPNQNRWDPNAGRLSPPGSSTKPPHRGSVASGGNRWSEGTTPGSTTVGPREATAGRSLKSYEDLDAVCWIWIWRTQLLSLRAGLKAVVGRSSVLLLSKISFWRSNTVFVGDACFASSEVFLSTCWVFFCLFVAFDVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJR6</accession>
    <name>A0A5N6KJR6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_005302</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJR6"/>
    <dbReference type="OrthoDB" id="2392202at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207:SF0">
        <property type="entry name" value="RIBONUCLEASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="RIBONUCLEASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNase III" evidence="3">
        <location>
            <begin position="115"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8303942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="392" mass="43501" checksum="3BD38461E99EFDBF" modified="2020-04-22" version="1">MIFLISNSTSHEKISKLLNALEGILDESGVDEVEALIGKPAVLQAIELRNSLRTQEKADSNSNAPRAETSSRDFVNQNVGRSISNLQLTPWTSSSIPSELPPLPAVFDPTLEVAAFTHHGYGSGKVSDLSYERLEWVGDAYIYTTSTLLISQTFPALLPGKCSQLRERLVKNVTLADFAHRYGFEKRAKLPDSLLPGAKYSAKDQDNTKVMGDIFEAYVAAVVLSDPTNGVTRASEWLKSLWAMTLSKEIKQEERAEKKLDSPLWRLRGAVDFVQTNQASEVMYNPKEKLQHALGSKISKLTYKDIGAVRKDVNTKLAVFSVGVFLTGWGEVDKQIGYGSAYGKKEAGMKAADMALHNKKMMSMYLGKKKIYDAQQEKERIALEKQEDSVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJS3</accession>
    <name>A0A5N6KJS3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_005299</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I 75 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJS3"/>
    <dbReference type="OrthoDB" id="10249365at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02773">
        <property type="entry name" value="MopB_Res-Cmplx1_Nad11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.740:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.210:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.740:FF:000013">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000283">
        <property type="entry name" value="NADH_UbQ_OxRdtase_75kDa_su_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054351">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010228">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019574">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015405">
        <property type="entry name" value="NDUFS1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050123">
        <property type="entry name" value="Prok_molybdopt-oxidoreductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01973">
        <property type="entry name" value="NuoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF13">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105">
        <property type="entry name" value="RESPIRATORY NITRATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13510">
        <property type="entry name" value="Fer2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22151">
        <property type="entry name" value="Fer4_NDSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22117">
        <property type="entry name" value="Fer4_Nqo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10588">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09326">
        <property type="entry name" value="NADH_dhqG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00929">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53706">
        <property type="entry name" value="Formate dehydrogenase/DMSO reductase, domains 1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51839">
        <property type="entry name" value="4FE4S_HC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00642">
        <property type="entry name" value="COMPLEX1_75K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00643">
        <property type="entry name" value="COMPLEX1_75K_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="4Fe-4S His(Cys)3-ligated-type" evidence="13">
        <location>
            <begin position="120"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="12">
        <location>
            <begin position="259"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="698"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00070722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8303937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="725" mass="79350" checksum="53037ECD7D648AA8" modified="2020-04-22" version="1">MLRSTLSRSALRSSRQSFCAARTFATTNRRQAEVTLTVDGKQVSIEAGSALIQAYIVIMSKSTRCAYSKRTPLIRIYFRKLMIAGNCRMCLVEVEKAPKPVASCAWPVQPGMVVKTNSPLTHKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMRYGADRGRFHEIGGKRATEDKNIGPLIKTSMNRCIQCTRCIRFANDIAGAPELGSTGRGNDLQIGTYLEKNLDTEMSGNIIDLCPVGALTSKPYAFRARPWELKHTESIDVLDGLGSNIRVDSRGLEVMRILPRLNDDVNEEWINDKTRFACDGLKTQRLTTPLIRKDGKFLPASWEQALVEIGAAYRDFAPKGNEFKAIAGELIETESLVAMKDLANKLGSENLALDQPSGNAPLPHGIDVRSNYLFNSKIWGVEEADAILIVGSNTRHEAAGLNARIRKQWLRSDLEIGVVGETWESTFEFEHLGTDAAALKDALAGPFGKKLSEAKRPMIIVGSGVTDHADAKAIYETVELVLFEVGFTTPSQEVAETKPKFVWLLGADEFNAADIPKDAFVVYQGHHGDRGAQIADVVLPGAAYTEKAGTYINTEGRVQMTRAATSLPGAARTDWKIIRAISEFLGAPLPYDDVAALRDRMVEISPSLASYDVVEPVALKQLSKVQLVDQNKGSEPTGAPLKKVIDNFYFTDVISRSSPTMARCSAAKETGNPETNFLAPGYSSENPRGRVAYGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJT4</accession>
    <name>A0A5N6KJT4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005404</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8304060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJT4"/>
    <dbReference type="OrthoDB" id="9895617at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022234">
        <property type="entry name" value="DUF3759"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450:SF1">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12585">
        <property type="entry name" value="DUF3759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8304060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="108" mass="12778" checksum="FA09D2371CEF0AAF" modified="2020-04-22" version="1">MLISLIGKPVSHAFAKELIAGFAAGEVDKLAETKGEDWVREHRLREKSKEQAEHLYDQHYGQDDQYDPYVALFILHRTFIFQAFTNIYLLYRNQRGPPEHFNKYDNDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJT5</accession>
    <name>A0A5N6KJT5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Atos-like conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJT5"/>
    <dbReference type="OrthoDB" id="8625101at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033473">
        <property type="entry name" value="Atos-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025261">
        <property type="entry name" value="Atos-like_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051506">
        <property type="entry name" value="ATOS_Transcription_Regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13199">
        <property type="entry name" value="GH03947P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13199:SF11">
        <property type="entry name" value="PROTEIN ATOSSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13889">
        <property type="entry name" value="Chromosome_seg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13915">
        <property type="entry name" value="DUF4210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01177">
        <property type="entry name" value="DUF4210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atos-like conserved" evidence="2">
        <location>
            <begin position="361"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="712"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="772"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="712"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8303459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="793" mass="87546" checksum="B9E2C9F62E9B47DF" modified="2020-04-22" version="1">MPIFQDDLELGDGRAVFSSHKPNVSDTSVTEPETRTITRKYSEDSIRTELCEGPVPDTPEGPKTKPTLELDTNLNISYNDITDRGELIERLKMGESPNWLPNLNLESLLHSRNPETPIRKTPSNYSNSSPLLPPAEISNISRPPSVDKQITQAGLGIERPRSALHSGNFTEGPQQNIPSGLEQNVKDFGSGNLPWLATSPPRNFNPFQLDPRFPSVDRFEAYSSRPRTRAPSLSSSYSSSFVLKAPTSPLVQSESNDDLDFDSHLNSMDITLGMPRTDSRHHTLQASNSTHSILSIPASATSNKPLPSPMRNNSYPYQAHQPRRSLASNTMPHPTSSPQTPIFSRSRRPSFSDVSPLHASMVGSYEESILRGRMSTTPSKPLDFLAQIGVLGFGKCKSSLKCPPHVTLPFPAVFYDYESTNHGRSGKPEDGPSPYVGCIDLENGLPSPEQTKDSQKKRRNATLDRIHMDNRDIDPSNSGQVSDLGIRRAEKQKRRSTSPRAPPGGSYRIPEKGQLQIIIKNPNKTAVKLFLIPYDLTGMEPGTKTFIRQRSYSTGPIIDSALSSSSHLSTPTINHLLERPTLRYLAHIHICSPSRNRFYLYKSIRVVFANRVPDGKEKLRNEITLPEPRFTTYKAARESSFGVAGAALAAEKAIRRKSSGFPLSGHKNFDFGSDNRSGSGAVDPIPFQFPAKRNMMNLDRAIEPLDLIEGKSTTSKDSLKSGTTSWEGNDGMEMGIESYNKQGRQSPAEGLLATRLRELGVGLAMAMEVENEGGETGLRREDASVNNLSHHWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJT6</accession>
    <name>A0A5N6KJT6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8304056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJT6"/>
    <dbReference type="OrthoDB" id="5327547at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="409" mass="43631" checksum="906E03EB1D9B6B7B" modified="2020-04-22" version="1">MYLQWEKVMSNSLDSLTQTSVDFQSNFAPKTPGAKVAVKSTVTVISGGLAIAAVIGTCWIPGAAAFTLPVLGTQITAGMLTIGAGIGAGTTSLIGTMANDIQDGKESDELSVLEISDYLPVMKQLALASLEFSHNGTFSNGQVNGNSVGNMRDLLTGGAFSGDEVLQAYVGGENGLDGLFSRYAAIKLLQAYWEAQNAFFIYIPEITKVCSGWHGNTGGKDQGRFCGEKGMMILAGVNKDSSFSAPTGIDNGKVSSIGGYGIQLQQLYQSTYNMYTGHGLDSYKDVPWHMNNIAHEYVGNNDAAKAYTTAGFFTLPVCELKSYNWKQSDHMKESPPCDCSIYVASLMLLLSTHQYPPPQTPSKPLNSNSNSNSNSNSNSNSNSNPSLKSSLHFPNNIPSITKNPANQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJT8</accession>
    <name>A0A5N6KJT8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJT8"/>
    <dbReference type="OrthoDB" id="5385072at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="233" mass="25029" checksum="A95B617DC822D2A1" modified="2020-04-22" version="1">MMADVPRRKPMPPGFQLPVQTSYNNHSRTRTTSTNTFSSINYPPQHPQTLYPGNMQTNGYSSRRTPSTGTFSTTASSGNGPVPYRGSQDLRRSTSSRSGNLQPQGYVALMRKQKATVWCDRSQHEDPRLIAQQKAAKERAAAAVLGGPLQGRISTGGTNSLVGSNRVTAKIRHHGKAGLVGYSPGDLVGGVVGVPMRLSASEVEGGDSDDDGDSGRILYHRRTGSGRSSMELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KK34</accession>
    <name>A0A5N6KK34_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8304047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KK34"/>
    <dbReference type="OrthoDB" id="3555548at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="204" mass="23378" checksum="9A55A5EBF5A7EA15" modified="2020-04-22" version="1">MPNEIPGRHREDDTLPTERQVSGSIDNIFQRNQQNSKFIYQDPLTKFFMEIGRRNASYITKIMIQGRWNWIIGKWKETGSQPVGLHDLVPIYTLILNEVCKNIHTVTLHDDDQGYPQINKLGPPGTDRDQEISDSVEKLVHGLQNLQKLQLGHYEYVPAGCGYDPGLSGSKTVLHVQPNDEWRKALKWMAFVEERAKVRIAAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KK37</accession>
    <name>A0A5N6KK37_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8304062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KK37"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8304062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="98" mass="11590" checksum="8E0158C3BF805339" modified="2020-04-22" version="1">MWMMLLYLNPSHLPSILSPLINNYKLYNFIFILPLQYKLLFQTFNFHQINLSKWFSAGVRSFPLHLIHSSWGFRPHHDTTTLILSITIDEVALTNIFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KK53</accession>
    <name>A0A5N6KK53_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KK53"/>
    <dbReference type="OrthoDB" id="442677at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="148" mass="15696" checksum="6F21EBC095AF3BD5" modified="2020-04-22" version="1">MLPRVLRVVRAKAQHKQVSSRPTARQPKSSKSSQIYNPKVDPNQASLQGRATKLLGKAGGAKFKKTGANDTTLGSRGHKPATGDGEVKSGMAGIKAPESFVFEGYRASASKGKPKDLKLGGKGGGKKKGKPRTRSSNRGAEWKKRGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KK59</accession>
    <name>A0A5N6KK59_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial import protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8304077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KK59"/>
    <dbReference type="OrthoDB" id="2148490at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070096">
        <property type="term" value="P:mitochondrial outer membrane translocase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013262">
        <property type="entry name" value="OMP_MIM1/TOM13_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28241">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28241:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08219">
        <property type="entry name" value="TOM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="18298" checksum="1DFA4197F2D2A7CE" modified="2020-04-22" version="1">MSSDEQLNPLAESGITIPSDSEQYSRNEDGTSPSQSSSNSPQMILYSPPTFWGLLRGAAINLVLPFVNGLMLGFGELFAHEAAFRLGWSNTKVFPAARRSVGPGIEVKDSPIERKRREGNLDDLTIIPNSFLKREQEIHQWHLQLRDMQRKSILGLLMVFDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KK61</accession>
    <name>A0A5N6KK61_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_005416</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8304075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KK61"/>
    <dbReference type="OrthoDB" id="2148490at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032979">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20069">
        <property type="entry name" value="5TM_Oxa1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="YidC/Oxa/ALB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF66">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Membrane insertase YidC/Oxa/ALB C-terminal" evidence="11">
        <location>
            <begin position="156"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="359"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="418"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8304075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="474" mass="53167" checksum="9095394B4821BCCA" modified="2020-04-22" version="1">MIPSRGLRCSNQSVVLGRRRIESYGIRQFSSNVHRPIRNSTLLSNRGNSRLLSQSITRSPLSRANTLIRNATSIRSASTTPSAIPPVNSPIPSIETSTPEFKPAPLEVNADINPDILSAPEHIGYLHSLGLDYGWGPTAVMEWMLEHIHVFAGTPWWVSIGLAAAAWRVLLFKPFLDAAENASRMAAIKQYTAPVQALMMEARKKGDTAEMMLHRAELQRIFKRAGISMWKSFMPAVQIFIGYGTWKLLRQMSEVPVPGLLDGGILWFYNLSIPDPYFILPLATSTILHFVLKKGGETGVSNLTPGMVYAMQWGMPALSLIFTSFMPAAVQLSFLVSSSISFGQATLFRTPQFRSWANMTPLPTPNSSPTENTLRMREVPSTAGDTKTPKRYSLDGSLGNVMEGFQSAKKGVVDMAKERRAKQDDASVKARADAYEEKRQRELAEEIKRQNEKRRLERERKRMERERRRGRRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KK64</accession>
    <name>A0A5N6KK64_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KK64"/>
    <dbReference type="OrthoDB" id="10506533at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="86" mass="10071" checksum="2F3472EBFEDD3A01" modified="2020-04-22" version="1">MKRGNDISTFLEYRSERDIDIDDPRVLIEVDEDEDEAEIDLHTCDHYKPNRRESKFTMKAMKKVNVLDVILINACCLLSIIAVFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLR0</accession>
    <name>A0A5N6KLR0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_004002</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLR0"/>
    <dbReference type="OrthoDB" id="60955at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061700">
        <property type="term" value="C:GATOR2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016239">
        <property type="term" value="P:positive regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037590">
        <property type="entry name" value="WDR24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46200">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46200:SF1">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="324"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="496"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="826"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="496"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="515"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="826"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="839"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="849"/>
            <end position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8304628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="901" mass="100715" checksum="81F2E6227AAAC54B" modified="2020-04-22" version="1">MSKSERGQRPRYSFTTPAPISNVCWRPACWTATGQGKRVAQVAVSYDDTSANRAQFSTVHLWDIARSAMPFKEIEVSNSAPTGILWSTRDLLWSVDKEGHFVQTDVAFSPRVIDRRSLSTFSFSSTGDVLMFLEERQAPKRVRPSMNSPELSSNFQQHPNTPSFAISHSDSEEDVVGSFLGPRRRRNHRRRHSGRLTHNMSTIPPNSTGIADSKVMSLEDAIQITGLYKPQQIMAIGHAPSTPKRAKYQFMSDCYLEYMTKNANETSNNVPLNITIAATIEHFAKGAEKARYYRLAQTWRLLGFTMDLLLVRRAESHRQYRLQNLSRKEGESKRISGSAKLDEEHDESNERTPRKSQRPVTSNEVAIHPAVRSIIAEEVESTSNMTTPLVRPVKDSVAGMKEALKTPMVENDTLVLPPSVASTIREPIPVAVPGSLTSEQTTSSIEGYDFYGMDAFKPAADFVPSKKQPLRLDYSEQNTYAQRMGLIRHDSGESFQMFSTSNDSQSKYLGGGSDSDAHSMRRDESLRERVSSWEGNVVSHSKTSSSLNSRPSEESMEKIPEELPEIVVPAPKISSPINIHRKPPPVPITVQSPSENDSSDPNLIETDFLPWPTDNDTEFVIPPLNPATLVQRAIEFETQTGALNASAMVLLLRRLLPPDTIDSIHAEAILRQYNHRLMTMQLFYESTLLRNLCVPLYPSLYASTQEQVSVGFYCTECNKPLENDPLVPGSEWSCPRCKKPIMPCPICQHRGDVPELEGPQTWWYCGGCGHGGHTACIGEWHADSGDEWKAGERHSGGMCPLEGCMHPCLEGRWRDELAEEKKERRARELEKEVKERTGHGGMGMGGLGRWDRSKSVRRDAREVGQSRAVEGVRVALGFGGPVVERRRSVKVLAPGEENVPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLW3</accession>
    <name>A0A5N6KLW3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLW3"/>
    <dbReference type="OrthoDB" id="5359669at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="313" mass="34254" checksum="4FB83212EFEA1D93" modified="2020-04-22" version="1">MGSFSHQSFSRSSPILAMAPQLPPQHSFNRPTFTSPFVKAPLPSPPSGSWLTPTSPPKSAAGRKRSRDEAALEDDQYFPQASFDPVVVENEEEWEYGPGMTLIKPSKGYVLSADSQTGTCPERPIMRSAKSQRIDLGSTPSMIEETIVANGPLPTPLQIGGPGPVQPSIDEYTRHLGIGWSKLSVDEDIQAAVRGWTKYIENHYPVNDAIIRLQSRGLASYLVEAQEGYFLFGEDLKKGRLVSTSLEKTFENLRGPSPIFEGDVVLEASETPKASSPVIDAMTSNGHVEEMMTDRILTTQLPTNAVEVEMDMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLW4</accession>
    <name>A0A5N6KLW4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004041</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLW4"/>
    <dbReference type="OrthoDB" id="5400539at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020999">
        <property type="entry name" value="Chitin_synth_reg_RCR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12273">
        <property type="entry name" value="RCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="189" mass="21619" checksum="D5562916B9756906" modified="2020-04-22" version="1">MDGDLSMIMERAANETVLECDRFGDCFESDHVPFWLTKTGQIIRWSVFWGLFIVFMLWIIIGYWHAKRRLSKGLKPLAYHRWMLNRRQRAQYDPAYHNPNAYYNQFATEGQYGMHSMPPPIYDPSAPMPPTYQPPAGATKVDPSQWRSQPTRRPADDGGESAPDYEAPPGPPPNLQTNNTGASNNPFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLW7</accession>
    <name>A0A5N6KLW7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLW7"/>
    <dbReference type="OrthoDB" id="2326446at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="61"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="252" mass="28940" checksum="A0B3632175BF2A3C" modified="2020-04-22" version="1">MGCVNPTDSSKPQIVLIPWDPNSLDHVERLIQQRISCGWDHEHVESWRKVQESGKLNNQWIVFADSDPDKDAKLLKHTEMYPQEKEPLVDSAISFWGKPRDIPSPQRTFTPIGHICLGLPSENYLNLGYVPKTGFYWISNFYVSRALQGTGLGKTAMDTVENLAISKPLYAKTLGMNAIKKFDPEGEEKYKALDLIIPPFSNQEWYERRGYKAYKDVEKLFGPRVDPAGKSWYWDAVFLKKEILNKKESAMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLX9</accession>
    <name>A0A5N6KLX9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLX9"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="140" mass="15566" checksum="ED955D87D6E21887" modified="2020-04-22" version="1">MDSDHFQQNPHNQDLPWDFDGSENIETIAQSQAATIFTSFDGLPRMGQDQYLMASLSSSPSMLNNDYTRAASQMPGSQNPSSWAHQAPLTPGFGDDGNGYSYDGRADYSCLEQQSLKAFDNIPRTTWQQPYANMTMTLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLY0</accession>
    <name>A0A5N6KLY0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_004062</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLY0"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0843">Virulence</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8304698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="529" mass="59706" checksum="DC7258ACE2DA6E50" modified="2020-04-22" version="1">MEYSTGTIMGYSTSSTALTIFISYVVYLVVGGLIHSQRLRIRAKKLNCQPPPILKNNLPLGIDQVTRALKALATKNFPPDTQKKHKEVNALTYITSVLGKDGFATIDEQNIKAMLGTQFPEFDLGAPRIDNFLPFLGPGIFAQDGKDWERSRALMRPQFARDNLSDLEMEERHFQVLLKALFEAGQDGWLGEVDIQPLLFRFTLDTATEFLLGQSVESQLAGIKTASGVKAEDTDIEAFGREFDIGNMALAKRSRFAPFSWLIWPKGFGKSISTCHGVIDRIVAKHLQKLEASGEAKNPDRYVFFEALAEKTRDPIELRAQVMNILLAGRDTTASLLGFAILTLARDPVRYQKLREIVLNEFGTFNDPKNITFAHIKTCKYLQWVLNETLRLYPLVPWNFRVANKDTTLPRGGGKDGKSKIFVKRGSVVEYSSYALHRREDIWGEDVNEFKPERWEARKGGWEYLPFNGGPRICLGQQYALTEASFFIIRLLQKFDQMESVDKEKVTFNLTLTMCSGNGVKIKLHAAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLY2</accession>
    <name>A0A5N6KLY2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Vacuolar import and degradation protein 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">EYC80_004060</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the EAF1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the INSIG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5364245at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025929">
        <property type="entry name" value="INSIG_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46459:SF1">
        <property type="entry name" value="E1A-BINDING PROTEIN P400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46459">
        <property type="entry name" value="E1A-BINDING PROTEIN P400-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07529">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07281">
        <property type="entry name" value="INSIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00573">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="HSA" evidence="18">
        <location>
            <begin position="1164"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="17">
        <location>
            <begin position="1435"/>
            <end position="1489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="87"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="537"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="676"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="934"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1357"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1526"/>
            <end position="1610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1623"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1742"/>
            <end position="1768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1886"/>
            <end position="1955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="559"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="574"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="600"/>
            <end position="609"/>
        </location>
    </feature>
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        <location>
            <begin position="647"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="723"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="782"/>
            <end position="803"/>
        </location>
    </feature>
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        <location>
            <begin position="835"/>
            <end position="852"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="869"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="894"/>
            <end position="906"/>
        </location>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="907"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="963"/>
            <end position="985"/>
        </location>
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        <location>
            <begin position="1025"/>
            <end position="1054"/>
        </location>
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        <location>
            <begin position="1367"/>
            <end position="1377"/>
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    </feature>
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        <location>
            <begin position="1571"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1625"/>
            <end position="1634"/>
        </location>
    </feature>
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        <location>
            <begin position="1635"/>
            <end position="1644"/>
        </location>
    </feature>
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        <location>
            <begin position="1742"/>
            <end position="1751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1917"/>
            <end position="1942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="1943"/>
            <end position="1955"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAB8304695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1955" mass="215765" checksum="CAAA1B383B05C2BA" modified="2020-04-22" version="1">MHVKDAHRPRVPAAATDRSNILKGHSSFGEERIRKETAARPRRPFETHSLALQPPSPSLNPSSESLETPSRTHSMINLTSSTLGGIYSATGHDDLEPETPSTPWGTGAQSPERRRSPPVYRRQQSFVTIPTSKSATVSSRIFRSILLFGLGLLYGLLVIHLHDDRRLAPLPVESIIKPSHNWRYLVFWGIAGVGLGNLLPLVDTLWEEQTQSQPVNFTGAPPDEEIETSDSQGILGGDWILVVRSVGVFVGIAYAIRKLPWASDMQASLTLALVNPVLWYLIDRSKAGLAFSATVGVTGTALLLASNSDLMPSPAASIINSTVSDQSVDYPVHGSENTVTRGSLDAGIWISSVLFCSCPHKKDFTFERATEKEVDRERAGSKKFTILLPKSSQCRDGRSMIFFQPDGKVEFRTRRASDPPGQCLISNVFGMNDQLIKTSQNLPLRSRLYPFFLKNGCRGRDIMSEVGAPYRRRLLQLKHDEQSRIVTSRKRKLRELFAICDNEGPIPEIPRLDPNAPPTTSAEAQFLEACDILQDRPFNESNLPTRRQLRSDSRKQKSPNRQPTSESTTTNVSHKIEHYFKRDTTIQRKSRGTTPIESNNEGRDIERNGDSIGATPETTEVSIRRSSSKSSQTILPTEPSADLEAASKNTSHSPITIQKQQHEFSKDFEIDRIKRVIESPPGSPGVDPRKAVPPSAEDVANLQEPVLFGANDENHHAATAHLPPKEAQEARLEDVEKAREHKGEQDAHSTTTPAHHDASTDTSPENDNNRYEDPERPDDENDVKKTPTESKSVRDANFQDEHNKKQKTQNEPSRAEVHGSSPMAADAQLRMEDQAASSSEVAAVTEVADSEAPSSQDMEESVSLAREVGNVEKDAIAEKSDESADIARPSAEGSIEKSRTTPKENEVPDSEGEEQTPLDAIDLDVATVKDSFESKTALDKGAVTNANVTDPAEEVSVRSSADTKTPPSGTPTSTTRRTPSSTPAPVQVPTERMTTRVASGAIRHKSVSEILGETPAPNTPPPSARTPTSKPETGSAINSPSRGSTPGSTRSLLQKTKEKSQSRLSTVVFAKKPSAPKASDPASLPRGVNSQPAHPYDDYFACLYLNSHNTQKTGYPPLDGLLQTAHKTITTSNAFVPITENQTTRILKRIYGLQNCHKWSLRQPKRSEEPIRPTTHWDILLQEMKWMRTDFREERKWKMAVAKNLAFACAEWIEASPEERKFLQVTRPSTVSAKAPKDIDMSDETNQLLSHSTPELIASAEVDSPMDDVDEELRLTLTDTVSPTAIFGLQDDDVVFGLSRSPATDKLLEELPLYGAPLSVPRNDLPTSEIDPDRFWRRPAVAISKYVEGRMELKFQGPPRKKSRFEYEEESEDEDTATDQPGHGRSPLPPEQTNIGLFDPANKHIRDRIHAGHQFRPPSEFPMPMQNFFEHRAFSQWTYSEDDELKRLVREYAYNWSLISNMLSSRSLLSSGAERRTPWECFERWITLEGLPTDMQKTAYFKAYNNRIEAAQRHLQALANQAPQQANANGQIIAPRRRTTSSQRVEKRRNQKHLTLVDAMRKLAKKRESSAQKQQLSAAQAAARRPAEQPQPWVAPIKTPQEFSRLKHDRDEAMRERIAAFQQREQNKRQEAQLRQRNATQQQVHPNVMPQQRVSGLPNGLVPPIGQPNGNGHLAVPGQNRPRPLPPQMGAAGPMPNNLRIPQAMSNGVPQAQMQGGLPPNPAVTAELANHAHRVSLQQRQQLMQNMAQQQGSPHPGQAQNSPPRMNGMPPQPGFVPNNMTSYNANNINGMAGSPGTPLPSPAQAGSPRVGLSVSGLPNGSLPSGVPYGEIERNVRRLNPHASTNEINKLIGENITAYNNNKQMQQRGLVQPPSGIATSAMNAAAGNSNLGMNGPPGQRPPMGIESSSPQMYAQMLSNHHQQRLQNSQQQQQAQASANQNHGQGNGTGAQQNGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLY3</accession>
    <name>A0A5N6KLY3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_004008</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLY3"/>
    <dbReference type="OrthoDB" id="300641at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.850">
        <property type="entry name" value="Peptidase S8, pro-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038466">
        <property type="entry name" value="S8_pro-domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42884:SF14">
        <property type="entry name" value="NEUROENDOCRINE CONVERTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42884">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024948751" description="Peptidase S8/S53 domain-containing protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8304637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="211" mass="24044" checksum="C45AD886DABD7E1D" modified="2020-04-22" version="1">MKLHSLIGLLGLGYLANAVDLRPRNYDSHDYYVLHLDPTANPIQVAGRLGLTHDGQLGELEDHHIFSSHKQEEDIVHTALKERKRRKRSLDDVDILDNVRYAQKQKLKPRMEKRGLMRPAPEGYEVDKRQNAEAPVDSAIVKQKAVQKALGIEDPIFKDQWHLYNPVQLGHDVNVTDVWMQNITGTGSIVAIVDDGLDMYTYSRAETSTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM34</accession>
    <name>A0A5N6KM34_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM34"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8304758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="96" mass="11248" checksum="39A9B75DBC3BDABF" modified="2020-04-22" version="1">MDDVTIRFQGERYAIEHKKMHLMFQHHGLDCNGTLGKKHRKLSRFDSLTHQSLSYAPLISCKEPRGRILSFLSLDFYSHQKFNIFKGLQTIIILLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM35</accession>
    <name>A0A5N6KM35_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM35"/>
    <dbReference type="OrthoDB" id="29058at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007144">
        <property type="entry name" value="SSU_processome_Utp11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03998">
        <property type="entry name" value="Utp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="98" mass="11305" checksum="0366F7F5EA19CF0B" modified="2020-04-22" version="1">MDIDIDMDFDFDFEDDEHDEPSKVEDAKEDAAAKNLRKLQEKEADKLEVKLSIARQRLKALTEAEEALNLQRAKMAKSPTIGSVNKNGVKFKIRERKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM75</accession>
    <name>A0A5N6KM75_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_004191</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM75"/>
    <dbReference type="OrthoDB" id="605656at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000001">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056263">
        <property type="entry name" value="RPN11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23594">
        <property type="entry name" value="RPN11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="8">
        <location>
            <begin position="30"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8304856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="356" mass="39710" checksum="0E2C027A2BC71570" modified="2020-04-22" version="1">MLASAGGMGGLSSSAPGSDNSNLIDNSETVYISSLALLKMLRHGRAGVPMEVMGLMLGEFVDDFTVRVVDVFAMPQSGTGVSVEAVDPVFQTKMMDMLRQTGRPETVVGWYHSHPGFGCWLSSVDINTQQSFEQLTPRAVAVVVDPIQSVKGKVVIDAFRLINPQSLMLGQEPRQSTSNLGHLNKPSIQALIHGLNRHYYSIGINYRKTALEENMLMNLHKQVWTEGLQMDDFRVEGTRNTERLRKLVGLAEGYEKRVKEETELSKDQLKTRYVGKVDPKKHLEDVGQKLIEDNIVSVSRQMIDKEASAPKEKNGANEHTPQDMDLDEEFWSGDGVNASLVLDLCFAFYYTDDVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM76</accession>
    <name>A0A5N6KM76_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_004080</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase g subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM76"/>
    <dbReference type="OrthoDB" id="2148442at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006808">
        <property type="entry name" value="ATP_synth_F0_gsu_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04718">
        <property type="entry name" value="ATP-synt_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4" id="KW-0138">CF(0)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="13"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8304721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="287" mass="30828" checksum="AB67AAD8FBF46673" modified="2020-04-22" version="1">MSLHISRTVLRQSTKLPGRAARRFESTSTKATEAAKDTASKASEKASDFQSKAGEGLSRVSSTAGPAIAGAAKNLGNALGKVGGRTGKLIAFIERQIPPTVYYARVGLELSKLVIQGQKIAVPPASTFQSYFQRIVKGIQSGNPRSAFSSAASSSTATPTGLFEQIRTIKTAQLVSGGVIFAEVLGFFTVILKLIIEGGVIMELCKTLGKIPVKCMERAWHSFSTVAWKAADGEIENYVCTSQNKQHNGGLEAPSSRIFALPYRSVGNLVYMFLLVRSYFPLRLMVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM80</accession>
    <name>A0A5N6KM80_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM80"/>
    <dbReference type="OrthoDB" id="3946221at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1168"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="560"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="640"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="680"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="750"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="763"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="817"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="864"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="878"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="897"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1020"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1054"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1078"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1104"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1131"/>
            <end position="1145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1280" mass="140550" checksum="972CD9641D5FFF6D" modified="2020-04-22" version="1">MTPRKRKAVSDLVPSSVVKRARGRPRSKLREEIRLSDGSDAAEQAEHPSVEPKLAEAEIHEELTPEEIDLLATIDANSRSPVSPYPAFQSTSTFPSSDDIEEDVVIARFHPGEETPPTTGWSSIMETSQLPNSSNSAQEEMSPLAESVKSAALSPESNDLVENDDENGGYGGVGFEDETDEDFDETRDVGQFADRPNGAIGEIQEEEFEEDFEDEIDDDIDHRPEFDTIMESEGFSLISLNSVPSLRKPMNGLIQDEGQNSAARPQNKNLLSVQNKALGNSFSNIAPEILEAATPGRNSRIPHILRVQNARIDDSFSSIPPEILEAATPAPARKNGFEMLQPESSSIVEENVAGYADSKSPSESPIMPPTETSELREDSLPTISAASHDAKTPRLMRQAPLRPSSIKKPESIPKDVSPPSQKQPRTSHLATSLKASKSPSPPVKESRKSASIQENEETETEPSVSQPAVQQANESLINSQIQSSPPAITSRRLTYTAHFQQQKQTNPKMTQTPEIIFSSPTLPPPIQPSRQPSERPESSNTNASSPAEKAGRILQDIVIPSSLPRSRSESLASPFKSPAMGRRSSSSIYPDTNVNGSMPNEQPPTSLAKFDPSGDSVSQHSRRRSWSRPILDEDPFAGNGVTQKRSSTDKSQSLTLELPSSRRMSVSLNAAIIPQHESSRTSNCKNTQPEETSRNGASEKAVPLTLSKEKKDADAKGSSSSLNKKWIAERAAVSKRISAAKSSEVMVLSSDDDDDDDNEDDKYDSKVPVSEEKQETRPEAQNVNHEGYINNKDEENYEDDESFGLLLETLDASNQEDQLHSDRSDNVERPRRAKIPSPWGTNSKHLVYSDDLASLSPNRDAKAPSVEESSPKSVSKELNVQNNSQTDLQTDGDETLDLSQWQIPQKQNFQPKIRSISSTRHDISALLRSPLGGLPTLSNRERGPVTEGDSSKEVPIPQKSYRKPPQNDSSGDTEKETSSFAPIPQKMDFQPRVRKTGDAPQPAPFSQPKTLSIFGKLGASRTSLPTPDTSSSSLVGTLTNTSPSRSNKLKPQPLQQDTLQNSSSQLSTSTTSAPINTKENREIENPKPKWTEHRLEAPIPPSPTKSILRSPQRSIDPPSQPSPSKNVVFASSSPQPSSPLTPQLSPTHWTRDHWLLLDSILQTWKPENQNDKDLDVNTTNESSKYGRRNSTRVISRLLGKTVNLKDKGVGIGDGGVRVFKNGSGKRGDDIGNERLRLEQWHLEAVDEFRGEVPGWDEAVVAKRVFALLVGEERRRRGIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM81</accession>
    <name>A0A5N6KM81_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM81"/>
    <dbReference type="OrthoDB" id="5358886at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024954871" description="Apple domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="29563" checksum="B2954F8F19F60E6A" modified="2020-04-22" version="1">MASALSTLGIFLLFADIIHAAFKPPFNNTLEPGVATECKTCPYSLCTNKEYYDYNTIVSLICWTAGTVIDGDSTWLRTSDDCYVTQYDLANYVGEYETDLSFCGQDSTIEHITTAPTTTKYNTECNICDDNSSCETIKYLKYGTDITVTCWTDLGSLVINDREKQLYSGEDYARCYETPSSSSRLVKRYEWDHGVWVQCYENNFTNPNPNETYWYFTTDFCYVREVDFWESLFDQYRFPNCDLFEGVGGGGDDDGDDTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM91</accession>
    <name>A0A5N6KM91_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM91"/>
    <dbReference type="OrthoDB" id="5322539at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041:SF6">
        <property type="entry name" value="FORMYLMETHIONINE DEFORMYLASE-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="210" mass="22769" checksum="068B7CDAA1693AA4" modified="2020-04-22" version="1">MTEPKSPNFIISKWGIGWETPTIMISCYLLALIMALLHLWLFIYISGKNADGSDRVAPQTYISTSSNILANAFSFFLKTALATAFIQYLWHLLRVQTMTVSTIEALFGLKSNLFQMFTGATIRAAPVLCVLSVIMTSMGVAVSFPPGAINVVSVQRTSYNPVVVPTFNASFMGNGSGYAANHYSLATLSPISESADGSVSGFTSRTRRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM93</accession>
    <name>A0A5N6KM93_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM93"/>
    <dbReference type="OrthoDB" id="20105at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="515" mass="56311" checksum="907D8EC2E1EDB70E" modified="2020-04-22" version="1">MASAYLHLAVITLKPVHHGYKSYDYSPPTPPTSSRFPPAVTTTSYPTSSIPATSQSLPPLALTKSTKMSTPHRGLPPMTLPQPPQPPQPSQQVVPASLNQPTGSLQLPAPPQQWQGAEESMRNWLQAKAEEDKRKQEEEKTRQESLRLEQRKIEQDMLRTSLTGGIPPYMIPMVFAGMGGGNLPNSSLEWAQHYMAQAHQLQQHQAQQQLVPGQSQHTSPEQVQRRDSRPVFGGQHPVAVTLPSTPIGSTGPGFLPSYQMSPASRSRQTVGSLARTTANSQLPRLNTGEMFIQPPPAAPSMQILPGQSGHPLAQSQSAQQPQEPQSSPSIYFHHWQPPTSQAEHVSSPKKRKATGPQQPAPQPTSLPQYTSPSFSQAGSSISGTPSSRRRGHSRNRSDVSARGVDSYGRPSSRHRQTESGFSTQSLTSPSHSQTQEQVSGPVDPHRQSGGSNTVSSLLEHSGSRPRAHSQTQTQQSRSQRDLERQYSGVSEIRREERATEGEEARRSGQRNDGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM94</accession>
    <name>A0A5N6KM94_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7624 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004157</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM94"/>
    <dbReference type="OrthoDB" id="5230484at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056041">
        <property type="entry name" value="DUF7624"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24616">
        <property type="entry name" value="DUF7624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7624" evidence="2">
        <location>
            <begin position="608"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="501"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="523"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="588"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="798" mass="89000" checksum="22A9A94E11FDE639" modified="2020-04-22" version="1">MAVESPLLASPANVMSAISPYTDFSLSPCSPSIQRSPYYQSLSAQNYSGSNLQPTHIEDGLSPASAHLLSPMSDMVGPSPVTSNGTTTTDIEDEVADEAMNHEDIPRAGSQATVGSAQTYRRSFVLPLRLFNDATLQSAKALLDRSTPTPYQQSRSSRSSSRSSPRTSPKITQKASPRTCPRFSPNASPKESPHTSSRMSSDSHEVAEHANKSIESSLVSPPPISTDVRPIQFGLENQTPRAQTRQEVESFSDERRPSRPSSLEGITEEEDIKMPYSLDAGIPEELPRDFFEDDFDARTVHNADEEILALKTALNECWTLCNTLASLSSIHRERIFSFSGSGDAHEKAWKCCWRLCKKLYDSRDEDHESHVRPTLDLCRNFCQSLFDVRQKKDEIADSVLRVSFELNNHLYNTHDRNLPEAFRERTLDFYITLCHRLMKQRSELAEETDALLRACWSLAEMLFSLRQNKREGKMADEELLGSAVQACWELCDLFREGWTQVRPERGTPRPSQTTFRSPSDQMSRSSHTKSSSLASLSETLEEHPPTRYVILPETPTTDFEDTPITPEEDSPSVPNIMVLGSERPPRWSSAASSLSGYSQESGASTVTNGNQPEDLNLTRLKILILKASMNVGYSRTAVSSTGSPLTLQNFVKALPTGSFGSLPAHATLLSSYRTLVLSDPTFRNPSSLPLPGKKVSASDLAKSISWMMRAGQYTFLKDLFRMVFGFRIDEADARKNVSISPVIMSQRMTLSLVHHTLCLWRRWAQPNTTQDPFCIYSCPFDGYHNTNCTKSKSTLTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JMS1</accession>
    <name>A0A5N6JMS1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_010605</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000021">
        <property type="protein sequence ID" value="KAB8289694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JMS1"/>
    <dbReference type="OrthoDB" id="5416384at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF8">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="603"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="661"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="603"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="673"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="695"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8289694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="820" mass="93796" checksum="C619B9231CEC0FE2" modified="2020-04-22" version="1">MDTADLFRQALGSVSRARDAKSLRAREGSHESEDNSPRIAHTLTACCRCRQRKTRCDPNLPRCLPCERAGAVCEYFDTSKGKKISRTYVIRLQDKVRALEAELSQLVEEEGHPPNSEDIVRPGGLVRLSDDDETPRYLGPSSGIAMTRIVMEEAKKYTDSRSIRELVPEVRQRRSPTRSPDMRSQRKKSYPMISAVPAPTLPSRLVTDKLVEVFNQKAQYMLPTLHEPTFAKNLQEVYDGDNDPYKNFVLRMVLAISMQKLDTQYAGLADSYYLAAMGYIEDVIRPKDIKTLQCLVLISQYSMLTPTRNAIYYIVGLATRLCQQLGLVEEKTITQGVSLGLVDPLQLDMRRRLAWIVLSMELGLAHSMGRPNAFAIGKDHLDIQFFETVDDEYITADGILPGPISEKKRLAIHFFRMRLLQAEIRRMLYLRKRTEPKNEDHPWYAQMLQKLRDWLEASPENPPWSKTWFTGRYNTMIIFMFRPSPQVPQPSYRSAIMCYDAASSNIITQSEQIKTAMIDLTWPFLLSLFMAINSMLWSISYSEVRALHTKEELEEHITLALDIVTHSRERWPGTQSTSELYMKLTKACLKSYELGDNSLSSFSATSPPSSLADSPSASEHSYATSVSLNHSQHNNAQLNNTYHSPPRFGYVFNQMPEQMPPYGYHHPLPPTQPSFRSNSIFVSPSSGQSDRRFSYFPPEFTQPQPQPQPQQQHSQQPQSYPTPWVPVSNIHQHHIPAQASLPPMQNSLVNNAPYFTQPEYYNFPPHLFSPDNYDMGMRSGSLSQEQQTELMHSLETEGLTEIDNFMNHVPQYEHTTKFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JP81</accession>
    <name>A0A5N6JP81_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_010533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000021">
        <property type="protein sequence ID" value="KAB8289618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JP81"/>
    <dbReference type="OrthoDB" id="5243398at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040112">
        <property type="entry name" value="WetA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22934:SF24">
        <property type="entry name" value="DNA METHYLATION MODULATOR-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22934">
        <property type="entry name" value="PROTEIN ESC1/WETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="851"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="902"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="575"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="642"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="678"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="750"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="907"/>
            <end position="919"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8289618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="937" mass="97629" checksum="186863D6125F01A9" modified="2020-04-22" version="1">MAASTPGKKEALRKDASAERDAAARRTSENTASRAKAAASEKYAPPKKRGLDAAKNEGGNRASPFASRDEHKQRARPLTPDETKYEQARLLTLLRSINPVTVVDQVCKAVAYFGGIPGAPPPEDGIFPESANTRETGALFIGWLAEIFPDLSSAPETTAPKTQETPSAKAKRGRGRPPRDSKGPENGTSEPPGAANGFGFGPAVQAPTWGLPQSVALVNTAPPMSAPPVPVTAAAIPSASTATPKFNQPIQAESERPATPLKQQIENHAPETESTSKRRRGRPKGSRNKGKEVQTGGDGTGGTSHADATTSDAGPSEQHVQHPPAAAVAKMTTDQPTSSKESPIVPMTDISNKSGQPQLAYPAEHWNTESNAGHASSVLPPDQYSPEERAVLEAFHPDQGAPGGGPVEFNSTQGPPINNGTPTAGGAPGAGASAGTSAGAGAGAGAGAGASSGAGTATATATATGAQKRKRGPTKPKNAPMTASQNISGSQSQTGHAAKNISPLPAPAESPTVQKDGTSNVQWESVPPMVETLVPPPPKRQRKPKVPGANGPSTGKKGGSSVVSVATPPIPPSSIPASPATSVQSIQQGIQQTQQGTPVTRPADGLEAHYARFQDLGQQNGRSITPTIAPQGRQHQKSASIPQSTPQQMAQQTSQPPQQVQMQHQTSQQSHPRDDQTQKMTQTVPRNPSNNYFPNHAATNYVSQYPSNQASQRYGTHQPSPQMSNSYRAGTMSQASPQFSHAENAYRTASPHTITQPSPSFTQPDSAYRTSSSLANPSPTYSQPETSYNPRTTSLSTTAPSYSQPDYKSSAINQTSSYTRPTPTTHQQQSYNQFADPSYIDLPTLDLPTLGHTSASPYGQTNMNNLGGGSSRSNANTNSIYGTSSGLSNAFDGGSNDLLRVNRAGSGSYGAGGSAGGFDGGEEMRQRLMKGMLGRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JRA6</accession>
    <name>A0A5N6JRA6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arylsulfotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_010274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000019">
        <property type="protein sequence ID" value="KAB8289947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JRA6"/>
    <dbReference type="OrthoDB" id="5427350at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053143">
        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF5">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="540"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8289947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="588" mass="66050" checksum="4A95FA27B7A6B5F2" modified="2020-04-22" version="1">MHISWESIYLYAFKVYLGSQLIQYPGYHGIERPAYHDAAFDAGSYGEYPVHNYMSTDIVSPRLNILRASSLCRNDLYWVFSPRGKSVSEPGAMILDSAGNLVWFKGGYDQVYNLQVQEYWGEKYLTFWAGTDAVQGHGAGIYYMLDKHYREVHKVIAANGLAGDLHDFTITENGTALITIYDVVVANLSYVGIPQGYVWDCVIQEIDLATGELVFEWRAADHYPISDTLRDLPDGNGGVNSAFDFFHINSIDKDSKGNFLISSRYFHSITYLNGTTGDIIWILGGKKNMFTDLSGGRATNFAYQHDARWRHNRTAISLFDNGGDDGHPGNATRGLLLALDEVHMTAKIIREYMNPTEIHSVSQGNLQMLDDGHAIVGYGNTGAFTEYSTNGTAICDVHFGPQSRFGEGEVQSYRTFKFEWHGWPITDPDVRILTNGEDWLSFYVSWNGATEVQKWLLQGADSAEAKEEEWKTLDYADKTSFETEFEIPHLYPRYLRVKGIGSLNNVTGEEELLGVSFPLDVNLEKIWSLKPVRLEGSSSWPLLTLIAFAGVTGLVVGIREAMIWRRKKNGLALLRWRPRGLGVPLLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JRB1</accession>
    <name>A0A5N6JRB1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_010001</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JRB1"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14135">
        <property type="entry name" value="STKc_PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000440">
        <property type="entry name" value="CMGC/DYRK/PRP4 protein kinase, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000078">
        <property type="entry name" value="Serine/threonine-protein kinase PRP4 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044092">
        <property type="entry name" value="STKc_PRP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF103">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PRP4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="289"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="24"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="95"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="167"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8291317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="642" mass="71374" checksum="C0819D8FA10FBAA0" modified="2020-04-22" version="1">MVAGMVLTLIEANLMGMGGRTEVQETRQLQQHDDQSNGSEMEISTPAEEASPEAPEEEQVDEATLIEQRRKRREAIKAKYRGSGTPLLVQALHLGDKSGASTPGQGEDDSPSGPNASPAVSTPTTPMDPGSPSAFAITGDQDLANSHGNSAAGEEDGPSAADYDPTMDMREDRQRDGQRHADELSSEAYNETKPTSEQDVLLPAEIAPAEVKAPKAKDEFDMFADDDDDDMFAEDSVADEKPQAVTNGDVAKAVPIPQAKELDIGMLDNWDDLEGYYKIILGELLNGRYHVQANLGKGMFSGVVRAMDITTKKLVAIKLIRNNETMRKAGMKEIEILQKIKDADPEDKKHMIRLERYFEHKGHLCMVFEHLSINLREVLKKFGNNVGINLRAVRAYAQQMFLGLTLMKKCNILHADLKPDNILVNEARNMLKICDLGSASDATDNEITPYLVSRFYRAPEIILGMKYDFAIDIWSIGCTLYELYTGKILFTGRSNNQMLRSIMDCRGKFSVKMLKKADFAGIHFDDMLNFRSVEPDKLTGKDVVKMMAFAKPSRDLRTRLISASKGLTDVEQKELTLFADLLERCLALNPEKRITPTEALKHPFIAKMMRVPRNCEIKIIVFLSSSCMPWSNLDKHSAGVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JRC0</accession>
    <name>A0A5N6JRC0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_010006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JRC0"/>
    <dbReference type="OrthoDB" id="3561202at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8291323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="615" mass="68533" checksum="CEC7EE4E5568105E" modified="2020-04-22" version="1">MYQAPKPPPSPSRLASPATSSPVHRQDDESDRGITERLEGSSTLKGRKRENELHNEGNSSPSKKASRPLMNRVNPTSSNTAKKAELINSNFNESHIIGNVGTRTTRNKKNVTGQSNPDAKGPKLTSGSSGKKLDQLGTPPPDKTLKPKNPRLTGSKKRKREEAEKADIDTVNNQMQLRSSKEALPSAMSSHSILDSQDNTPSSSARVAGTQQPSGAIPAQRTITLNLSPAQMAQLSAKQDAATEDSAATLHTPPYSSHKSAGNQPPFGVDLTRIRIKFRGYEAVQESARRAARRAAQAARAAQEDAQRAARRAATENVEVSPHNPPSSSSTAPKNEKNPTKKNNARKKTEKKKKVSCGAAQAQWMGMQSPSVQKKSIRKADEAGTFFPNDIVIQTKEQNGKLVERCYGDYFVPQDFLSSFLRTKQAESADTFTYKVYLPSSFSDILVHDSCMPKYFKYTTATVSEAGLQKKVKIERMIRAAKGEKLMFEFDPSLGENDEIERQFANEFKFGESLEHDRVLKKDLRRRMKEAMTELESIKKNGLPFKEMRRYSLNFAEPTKKERIVELKQTILQQIEKEKNSETYEGRNERTQTAEEEWAAFQRDAQLLLDFSRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JTF5</accession>
    <name>A0A5N6JTF5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_008098</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JTF5"/>
    <dbReference type="OrthoDB" id="16510at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008504">
        <property type="entry name" value="Emc6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029008">
        <property type="entry name" value="EMC6-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20994">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20994:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07019">
        <property type="entry name" value="EMC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8292359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="144" mass="16067" checksum="3A17C81969B7D1AE" modified="2020-04-22" version="1">MQISPIVQESVMHNTKTLATLHNLTASLFGVAAGILGLESYPGFIFYIFFTLLTSALVYVFRIAPHMSKDTVGDRYFRGAWEFWTGGLVEGLSGLIDGSVEVVRGEFGMGWKRFMTRLRVRMGMNRMLSSGSIFSRGIGRPVYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JVD3</accession>
    <name>A0A5N6JVD3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">LEM-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_007923</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JVD3"/>
    <dbReference type="OrthoDB" id="2503928at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071763">
        <property type="term" value="P:nuclear membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12935">
        <property type="entry name" value="LEM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025856">
        <property type="entry name" value="HeH/LEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044780">
        <property type="entry name" value="Heh2/Src1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018996">
        <property type="entry name" value="Man1/Src1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47808">
        <property type="entry name" value="INNER NUCLEAR MEMBRANE PROTEIN HEH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47808:SF2">
        <property type="entry name" value="LEM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12949">
        <property type="entry name" value="HeH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09402">
        <property type="entry name" value="MSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="HeH/LEM" evidence="8">
        <location>
            <begin position="14"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Man1/Src1-like C-terminal" evidence="7">
        <location>
            <begin position="374"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="63"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="242"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="556"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="560"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="571"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8292180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="597" mass="66628" checksum="FE606E4359E72529" modified="2020-04-22" version="1">MSDELDYLQPGFDPSSLTVPRIRSLLVTHAIEYPSNAKKAQLIETFNRDLVPQARKILYERARAKRTSRGITDADASQESSTQESDVILPPPRTRPVRTSPAKVVRASVDISDDEPATYRNTRRSTRSISPVKQMPRASSPVKRVPRPSTKYSRQEEESHSDEEDAPQTISPVKRMPVASSPVKRAPGPSTKHPRQEEESHSDEEDVPQTVRKSRKSTTAQTAMVGARDNLDGVVKARNLRRETNFTYDNPFQRGSPPSDNRRPLSSHDNKRKSLGGSAAKEMEKRRTSVSRRRTVTPQANDGIRPPSSSTFEIPVSSLDGLKEYDDNGVEIGEDFTPEAQFELEREQRRGLATIQPRRKQKKGISMSGPFWMILLTTLLGYGAWYRQEKIAVGFCGVGREAHSIIPIRSNLPDWVQLIAEPQCDWCPQHAYCNTNYEVQCDQDFILKHHPLSIGGFIPLPPTCEPDGEKVRRVKAVADRAVEELRERRAKWECGGLVDEAGVPEATVEIATEELKKAVGQKRRKGMGEAEFEELWLGAIGEIKGRDEVVVGADGLNTPVVDQTPSQVPHSLASPSSAPSNDPLDTQWQDIISKLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JVK5</accession>
    <name>A0A5N6JVK5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_008141</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JVK5"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="213"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="110"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="164"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="189"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8292411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="352" mass="36697" checksum="5048418736335ED3" modified="2020-04-22" version="1">MAKTKEPKAAKASTKKTETAKATATKAKPAPKPVKKAATPSSDSDSDSDSGSDSESEEEKPAPAKAIKANGKAAKAAEKKEPAKKAAASESEDSDDSSDSDSESEEEAKPVVAAAKKVQKVVDAGKAKVNGAAKAVAKATEDSDDSDSSDSEEEEKKASGSDSDSSDSDSDSASEAEAEAEAPSKKRKAEAEPEASAKKTKTEETTGEDSGVKNLFVGNLSWNIDDEWLYREFEEFGEITGARVISDKNTGRSKGFGYVEFAKSSDAAAALAAKKGALIDGREANVDFSTPRDNTAPKERANNRAAQFGDAKNPPSDTLFLGNLSFDADENVVGEAFGAHGTVVNVRLPTDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXH0</accession>
    <name>A0A5N6JXH0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXH0"/>
    <dbReference type="OrthoDB" id="292964at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="52841" checksum="7C3FFF65276D8395" modified="2020-04-22" version="1">MSPAAIGGPHLRGTSINGIGPIHTTNREGVNDINTLKGESRVLPHLDDLVNAKPLVDRQSSLRKLLDAGEAAAKQAETWLDFKRPELALQEYIIAFTIAVEYIPQSPHYLDLRTKPDYPRLYAGLQKRLNTQHGKFEEVKRFIKEDNARSGISPTNSSQNSEQTASGNSRINAFTPIESDTYSNATNGKSGAISTPRGIESRSKPAIQPKPQGLHGKSIQTVNSISSSIPISSENDLAARFARLRSSNNTTLIQDPRIRTQHIVIPDEIIADQKPANVVSQPRQNARILRPLGPREMPRSSAIPLKTEKPILDMDTSLPMMPRVPDAIYSPAGSADVVSGNSQPPSISRGSSNLSGRRESSTSIQKINRNRMVADDTTDYFATSKVNNYTFDHNSHPDLEATPNKLSIPDSTSVTADELYNYLKLGSNTLSILLVDIRSREEFDEGHIMSQSIICIEPISIQKEMSAEDLGERIVLSPDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXI6</accession>
    <name>A0A5N6JXI6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8213 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_009195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXI6"/>
    <dbReference type="OrthoDB" id="3660917at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058526">
        <property type="entry name" value="DUF8213"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26641">
        <property type="entry name" value="DUF8213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024864745" description="DUF8213 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8213" evidence="2">
        <location>
            <begin position="20"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8293710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="143" mass="14557" checksum="8F3CEFFEED18D580" modified="2020-04-22" version="1">MRASCTPFLLLVMTTLAQASVTCVKVGATAKAIWTNSASQTCTWTGTVGSNFGTNAVNGGDYSCNGRCGAGCTGTALGNYYTQDCWNHDICSYFNNASGGASDPNCGSAYTAAEDDYLLGGIDGCDNACPQPNGKSLASITAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXJ1</accession>
    <name>A0A5N6JXJ1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C3HC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_009280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXJ1"/>
    <dbReference type="OrthoDB" id="2592092at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013909">
        <property type="entry name" value="NuBaID_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012935">
        <property type="entry name" value="NuBaID_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835">
        <property type="entry name" value="NUCLEAR-INTERACTING PARTNER OF ALK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835:SF6">
        <property type="entry name" value="ZINC FINGER C3HC-TYPE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08600">
        <property type="entry name" value="NuBaID_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07967">
        <property type="entry name" value="zf-C3HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57924">
        <property type="entry name" value="Inhibitor of apoptosis (IAP) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3HC-type" evidence="7">
        <location>
            <begin position="105"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="NuBaID C-terminal" evidence="8">
        <location>
            <begin position="244"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="351"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="351"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="374"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8293797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="48275" checksum="36DA0C5EC2E2D12A" modified="2020-04-22" version="1">MNTTKRKFNALLNGLGNKKSDSSLSAGAHEVNKIPEKPQPDIDSNMKKPRISYSSSTATANRLSSLTRASSAAVSELDNARRNLSPVAKLSPIPVSTEEPPKWAPYDRTEFLKRLKSFSNLTDWTPKPTRVNEVEWAKRGWVCQKKERVRCCFCNVEILVKLNKKEEDGREKEVYIAENIENALVDKYVELIITSHDESCPWRQRGCDEGFDIDLITTYLPGDFLRSSPETGQANPPSEINKVALMMSLCGWQGHKHDRLGQQLESVSCQTCYRILGLWMFKSRSVSATGQETEPAIVPGLDPIAQHREYCPWRDPVSQNGLAATHNTKLRALAGWEVVLRVLKTEHGLRVGREKNEKGSRRSYVSPATNEGGEYGDDSTPDFADDEDAKSIRDAKDKDLMTRFRRVKTFIALKKRASGEVKNKRFSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXJ7</accession>
    <name>A0A5N6JXJ7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXJ7"/>
    <dbReference type="OrthoDB" id="3557394at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="48"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="462" mass="52790" checksum="4579CA8F2C0205A5" modified="2020-04-22" version="1">MDTPIYRPLNNTIQEIRVLRILNGITRRFDEPLACSFEYISLTDDPSFAALSYTWGDMFYDSGYSPGKVIFNDTLGASPSVPISIDGLPVRIGENLLNALQYFRSEAAFKPIQWSSAKEPRFSSETRLWVDALCINQEDLTERSQQVSEMHEIYRKASRILVWPGVPRLDGQRELAAFIDSFEEEPWNTAQMLLRPHNRRLISALHNPGFDKCWEALEEIYKARYWNRLWIVQEVLSNSETWVYIGKELIQLLPLLTIGLALQYLEDREIEILPPYTKSIVESVRIPPNLPLLDGKLHFSDPEAKPMELLELLQTFRKFECRDPRDKVYALAGLSAPHSKELVIDYSKELSQVHRDAARLIIETTQRLEIICTHEKSGCNCPQGSHDKPSSIPTWVPNWSCIQEGTALRPGLLRGPTAYQLDRWNASGDTSANAHISDDGSVLKCKGILLGTITQIRCERRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXM4</accession>
    <name>A0A5N6JXM4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP citrate synthase</fullName>
            <ecNumber evidence="2">2.3.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ATP-citrate (pro-S-)-lyase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Citrate cleavage enzyme subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">EYC80_009385</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the formation of cytosolic acetyl-CoA, which is mainly used for the biosynthesis of fatty acids and sterols.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA</text>
            <dbReference type="Rhea" id="RHEA:21160"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.3.3.8"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Composed of two subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.8" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXM4"/>
    <dbReference type="OrthoDB" id="3261737at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003878">
        <property type="term" value="F:ATP citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06100">
        <property type="entry name" value="CCL_ACL-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000003">
        <property type="entry name" value="ATP-citrate synthase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000005">
        <property type="entry name" value="ATP-citrate synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000024">
        <property type="entry name" value="Probable ATP-citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118:SF42">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA-binding" evidence="19">
        <location>
            <begin position="179"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="85"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00054002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00060724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00062455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00076189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00083544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAB8293909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="800" mass="88520" checksum="ACA26B4456ACFDAC" modified="2020-04-22" version="1">MNSFNSPGFPSSIDFSTLNHRNLLNTDMFGCTSHGGGRDSRFKIQDSRFQESIEFGFIETHALTSTPYKNGWCVLFSPNPYLDPKYRPSYHPRGEKKDRQTDGKKERKKERKKERKRERKEKESFHYLRLNLQVKIFDCLLFFTMPSATASAAQGNANDNIRRFAAPSRPLSPRAEHTLFHDKTRCFVYGLQPRAVQGMLDFDFICKRKTPSVAGIIYTFGGQFVSKMYWGTSETLLPVYQDVGKAMAKHEDVDTVVNFASSRSVYQSTMELLQYPQIKSIAIIAEGVPERRAREILHAAAKKGVTIIGPATVGGIKPGSFKIGNTGGMMDNIVASKLYRKGSVGYVSKSGGMSNELNNIIANTTDGVYEGVAIGGDRYPSTTFIDHLLRYQADPECKILVLLGEVGGVEEYRVIEAVKNGTITKPIVAWAIGTCASMFKTEVQFGHAGSFANSQLETAATKNKSMKEAGFHVPDTFEDMPAVLASVYQKLVQDGTVVPQPEPIVPKIPIDYSWAQELGLIRKPAAFISTISDDRGQELLYAGMPISDVFKEDIGIGGVMSLLWFRRRLPDYASKFLEMVLMLTADHGPAVSGAMNTIITTRAGKDLISALVSGLLTIGSRFGGALDGAAEEFTKAFDKGLSPRDFVDTMRKQNKLIPGIGHKVKSRNNPDLRVELVKEFVKKRFPSCKMLDYALAVESVTTSKKDNLILNVDGAVAVCFVDLMRNCGAFSAEEAEDYMKMGVLNGLFVLGRSIGLIAHYLDQKRLRTGLYRHPWDDITYLLPSLSSGAPGTEGRVEVQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXM5</accession>
    <name>A0A5N6JXM5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP citrate synthase</fullName>
            <ecNumber evidence="2">2.3.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ATP-citrate (pro-S-)-lyase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Citrate cleavage enzyme subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">EYC80_009385</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the formation of cytosolic acetyl-CoA, which is mainly used for the biosynthesis of fatty acids and sterols.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA</text>
            <dbReference type="Rhea" id="RHEA:21160"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.3.3.8"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Composed of two subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.8" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXM5"/>
    <dbReference type="OrthoDB" id="3261737at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003878">
        <property type="term" value="F:ATP citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06100">
        <property type="entry name" value="CCL_ACL-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000003">
        <property type="entry name" value="ATP-citrate synthase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000005">
        <property type="entry name" value="ATP-citrate synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000024">
        <property type="entry name" value="Probable ATP-citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118:SF42">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA-binding" evidence="19">
        <location>
            <begin position="126"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00054002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00060724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00062455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00076189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00083544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAB8293912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="747" mass="82234" checksum="3F85309A9B070F2D" modified="2020-04-22" version="1">MGARKLIVSSSQSLPRSQISALISSQRRKERQTDRRKERKKERKKERKKERKERKGKFSLFETQLAGKGFLRCLFTYGSPFTIFDCLLFFTMPSATASAAQGNANDNIRRFAAPSRPLSPRAEHTLFHDKTRCFVYGLQPRAVQGMLDFDFICKRKTPSVAGIIYTFGGQFVSKMYWGTSETLLPVYQDVGKAMAKHEDVDTVVNFASSRSVYQSTMELLQYPQIKSIAIIAEGVPERRAREILHAAAKKGVTIIGPATVGGIKPGSFKIGNTGGMMDNIVASKLYRKGSVGYVSKSGGMSNELNNIIANTTDGVYEGVAIGGDRYPSTTFIDHLLRYQADPECKILVLLGEVGGVEEYRVIEAVKNGTITKPIVAWAIGTCASMFKTEVQFGHAGSFANSQLETAATKNKSMKEAGFHVPDTFEDMPAVLASVYQKLVQDGTVVPQPEPIVPKIPIDYSWAQELGLIRKPAAFISTISDDRGQELLYAGMPISDVFKEDIGIGGVMSLLWFRRRLPDYASKFLEMVLMLTADHGPAVSGAMNTIITTRAGKDLISALVSGLLTIGSRFGGALDGAAEEFTKAFDKGLSPRDFVDTMRKQNKLIPGIGHKVKSRNNPDLRVELVKEFVKKRFPSCKMLDYALAVESVTTSKKDNLILNVDGAVAVCFVDLMRNCGAFSAEEAEDYMKMGVLNGLFVLGRSIGLIAHYLDQKRLRTGLYRHPWDDITYLLPSLSSGAPGTEGRVEVQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JY00</accession>
    <name>A0A5N6JY00_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_009470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JY00"/>
    <dbReference type="OrthoDB" id="6019893at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8294008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="382" mass="42393" checksum="513B297E6233510D" modified="2020-04-22" version="1">MTEYLDAEFDQEDADNMGDIVEESKTEGKRSASRGPSERGSSRASSRTPSRSQGFNRSVDDMTPEMEARLVGSVRNSKRYSAISIADVADRHLRDKTDAIAHIIRNISDQCAAAVEGLMMAHDADAEAEELAMREKQRRHRESNLSTMTSDGEQSGEDSMLHPSGRPSSVPPTPDLSHRSSTAMSIASSVTTPERHSQQYHVRDDLPTKIIEDSDEDLGGRSDTGSMRHSLNGKPALLHRPAAINALEETWNGRRFIALILPQPYHLFLPTRSHFLFHPAYLRRRRLNGEAISFDVLLLGLAARHSPSQFFISLLVFFFVDAGGLPAVVGWIDGMICTVISYSFSFIFLFLLVRWSDGASELRIIPDVISQLVSCMVACNTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JY03</accession>
    <name>A0A5N6JY03_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Oxidoreductase FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_009492</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JY03"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000011">
        <property type="entry name" value="Sulfite reductase flavoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF109">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] FLAVOPROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfite reductase [NADPH] flavoprotein alpha-component-like FAD-binding" evidence="6">
        <location>
            <begin position="20"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidoreductase FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="112"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8294034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="29164" checksum="68577DBB3B664E10" modified="2020-04-22" version="1">MRTRRRNFLPLVAQKVPMNSSSAHPSFHDIARIISPMKRREYSIASSQAVNPTTVALMIVVVSWVDPKGRDRFGQATRYLSSLPIGSKVTASVKPSVMKLPTLDTAPLIMAGLGTGLAPFRAFVQYRAMQKAQGKDIGSILLYMGSRHQREEYLYGEEWEAYQDAGVITLLGRAFSRDQKQKIYIQDRMRETVSDIIQAYIKDEGSFYLCGPTWPVPDVTEVLEEAIREEGRLSGKKVDGRKEIERLKEAGRYVLEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZL5</accession>
    <name>A0A5N6JZL5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8294984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZL5"/>
    <dbReference type="OrthoDB" id="10635524at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8294984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="154" mass="17650" checksum="9CA15C5EFE89EE5B" modified="2020-04-22" version="1">MRASLSFGSHGNFRLKFPPLVLPSIRLYNTIPSSPSYPIPFNSIHLAINQQNRYPIALILLRFFTMMLEFSTLSSSIPPSQSSTGSQCLTESFFPIKASHHSYELFQSNCGKMESRNYMQTSRRHPKCNITRKEKQNLCAMNLTMHMHMYSSPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZL7</accession>
    <name>A0A5N6JZL7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ketopantoate reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_006936</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8294986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZL7"/>
    <dbReference type="OrthoDB" id="5302359at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000017">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000424">
        <property type="entry name" value="Meiotically up-regulated gene 72 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF25">
        <property type="entry name" value="PROTEIN PAM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="3">
        <location>
            <begin position="200"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="534"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="629"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="431"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8294986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="716" mass="77442" checksum="986D2688577785D1" modified="2020-04-22" version="1">MAPTPPRLRILSVGGNAVSAFLSWRLQATNACDVTLVWKSGFDAVYQYGISFKSTSFGNERFKPRHVVRTPEEAASNKDGPFDYVLLCVKALPDVYDLAAVIESVVTPQHTCILVNTTHTLGVEAHLESRFPSNVVLSLVSGAEIVQLGASEFEHKGSTEIWVGPANQNPSMPSTIQGDMAEALAMTLSGGQVDCHVSPNIRQQQFERMIGPIAFHPLSVIFETPSHSALLEKVGVKSMVSDLFDELINLAQAQNCVFPSNFKGKIMEEMSKPSEVNSIMYQDYAAKRPMEVETYLGSPIKLAQLVGVKVPRIETLYPILHNLNIVNQQRKDTALAPMASPMVPPMRMSSAPPPRAMMNGGPPNNAGRGRGRGSMGPPPGMRRGPGGPPNGVGRPPNGFPQSRNQSRRGSLEGNDLEEFSHLVLYDDIPEAGESPYPAEAGGAGAGAGAGAGEATLRERELMLRQRELALREQEMRLRQSGPPPRSRRGPPTPSVRNGGFDDDDDDDYYVDPADAPVVPLIDPDNFDMMSVTSRRNRAKPAPTKQQMRANPEFDNIPPPRRGAGFMRGNLPRNRSSARIISQVPGLHDNLMDDPLMAYASNRYGIVDRQAMGMDSRASSLTAARLDELQYGSSGPPIHGQGGPYPTPRRTSQSPGNPYSPQAQRGNGRPSPPNGYVGGPMNGRPSPPGGMRQPAPRHPPGQGNMAAPQQVEQYAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZN8</accession>
    <name>A0A5N6JZN8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZN8"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="98" mass="10742" checksum="6B2A37F4FABA8993" modified="2020-04-22" version="1">MFPRFSDRLIGPSPNPNPSRPARRKAKAKAKPRQEETGQPLLVVQAAGNRSGTLNREGGGFQVSRLDPGSLLDKPNHEAGEIESSGWCMLRWTIHGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZR7</accession>
    <name>A0A5N6JZR7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZR7"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8295034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="112" mass="12725" checksum="377AA6A59C652673" modified="2020-04-22" version="1">MISSYHNHHLTLSAALSGSALSNDSRTISILASAYCSTGLVVAEYHTHTHTPYTIHHTPYTIHHTPYTIHHTPYTIHHTHHTPYTIHHTPYTIHHTPYHIVTHLQNNASKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZS4</accession>
    <name>A0A5N6JZS4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_006977</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZS4"/>
    <dbReference type="OrthoDB" id="438291at2759"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04252">
        <property type="entry name" value="AAK_NAGK-fArgBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1160.10:FF:000011">
        <property type="entry name" value="N-acetyl-gamma-glutamyl-phosphate reductase, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011242">
        <property type="entry name" value="ArgB_GNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041734">
        <property type="entry name" value="NAGK-fArgBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006855">
        <property type="entry name" value="Vertebrate-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342:SF0">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04768">
        <property type="entry name" value="NAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036441">
        <property type="entry name" value="NAGK_DUF619"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51731">
        <property type="entry name" value="GNAT_NAGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="8">
        <location>
            <begin position="344"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8295031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="447" mass="48725" checksum="36F5A67196117082" modified="2020-04-22" version="1">MLALRSRAAVVARRARTATSKFPSSSTARSLPQATTAVALSSRRQYSAPAADSLSTRSTVVQLLSNIGSKREVQQYLSHFSSVSSQQFAVIKVGGAIITEHLESLTSALAFLNHVGLFPVVVHGAGPQLNKLLEDAGVEPQFEEGIRVTDGKTLAVARKLFLEENLKLVEKLEEMGVRARPITSGVFGADYLDKEKYNLVGKINKVNKGPIEAAINAGCLPILTSMAETPEGQVLNVNADVAAGELARELQPLKIVYLSEKGGLFNADTNEKISAINLDEEYDSLMSQWWCRYGTRLKIKETKQLLDLLPRSSSVAIIHPADLQKELFTDTGAGTLIRRGNKLATASSLSEFEDTQKLKDVLVRDREGLDARATVDRYVDGLKNKEFKAYFDEPMDALAIVLPPKSPSSLSNLATFTITKAGWLTNVADNVFAAIKKDHSKLVWTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZS5</accession>
    <name>A0A5N6JZS5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">V-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_006979</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZS5"/>
    <dbReference type="OrthoDB" id="190375at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15874">
        <property type="entry name" value="R-SNARE_Snc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016444">
        <property type="entry name" value="Synaptobrevin/VAMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45701">
        <property type="entry name" value="SYNAPTOBREVIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="4">
        <location>
            <begin position="31"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8295035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="230" mass="25983" checksum="EC5992C73472B317" modified="2020-04-22" version="1">MADHREPQYDPYIPSGGAAGAGGQQAGGNQRTAALQATIDDTVGVMRENINKVSERGAHLDSLQDKTDSLAVSAQGFRRGANRVRKQMWWKDMKMRMCLILGIIILLVIIISLLPSIKKVQTKNGKRNVNDGILGYRDYEKRDMNTCTEFHGTKRLTPNPLGLLHGETLHSWEGNERGFSDSGVDIFEIFYMMVLPFFFPYEGVTLISDLQIDDTKRNKWLFRLNGDLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZT2</accession>
    <name>A0A5N6JZT2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZT2"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="80" mass="9351" checksum="6E9F2CC41B0937EF" modified="2020-04-22" version="1">MDGGRGGKEGGRYHTHTHTPYTIHHTPYTIHHTPYTIHHTPYTIHHTHHTPYTIHHTPYTIHHTPYHIVTHLQNNASKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZT6</accession>
    <name>A0A5N6JZT6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Malate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8294892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZT6"/>
    <dbReference type="OrthoDB" id="1859733at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021851">
        <property type="entry name" value="DUF3455"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567:SF3">
        <property type="entry name" value="MALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567">
        <property type="entry name" value="MALATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G13800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11937">
        <property type="entry name" value="DUF3455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025065956" description="Malate dehydrogenase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8294892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="21272" checksum="7152ED9AC58F1B5D" modified="2020-04-22" version="1">MMLSISNLILLLASAVAAVPVNTVPTLPLGASELPAPTGTLAYVALGRGIQNYTCSAIGATPAAIGAVASLYDATEFAKCDGTTFTQFPNIAVYTNLPSSSSASFMGLKALGKHFFDASGTPTFDLSAVSKILYATKTGDIAAPINASPGPADTGAVDWLSLAAKGTYTSVGLAEVYRVETAGGNPTKPCVTVGVESVPYAAQYWFYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0W7</accession>
    <name>A0A5N6K0W7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008629</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8295807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0W7"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000073">
        <property type="entry name" value="DnaJ domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052594">
        <property type="entry name" value="J_domain-containing_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="9"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8295807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="618" mass="70831" checksum="2B98E26EB553E000" modified="2020-04-22" version="1">MTSPRLPPDPYKILGVDKDATLPQIRLAHRKLILQCHPDKVQDPKLKAIKGDEFQKVQEAYEILSDVSRRSEYDQSVKLQKLRDELGKTSTSTSTSNSNPTPASTSKTYDYNVRTAEPRTTTYSSSYPKATQKPAKEPNVYSKPAPRSYEDLYDEPVRPSVRRSKTTAREPEKEEKDRRKHHEEDEREKFRRKVEKEAKRDHGDRKKSREKEKRRSPEEKVRPSTYAEDESSEEEYRRKAAERTARRAEETMRAEMASRAQQDREARDRERRDWDRERERERELRDRERERERERDREPPAVKDSPMGEKWKDHMANAARYVQASRRDSEIKPEVPFAPAPPVMPTMRRAETFAAPSPSPYNIRYETVRPSAYGNHSDDETPRRSSAARPSRRSAETPSKTKETPKPSRRSTREAPYVNTGSTSPTKPTLHKQYSEPPIVGVGSGRREPSRSKTEYPREPPPPPSFSRAATFTQGVGIKEDIRDRARGPGRVVQEPESESDSGSDSESPSPTPQYSHVRQPRREGPEPNGTTKTYVINPNGRSELKNSSYRSDLRDDAYTKQNRTPSDGRTSRPPLARSGGSTSRQARSQSRGYHPTSAPEPAEPIVFTAQPNRDPIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K181</accession>
    <name>A0A5N6K181_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8295769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K181"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018853">
        <property type="entry name" value="DUF2457"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10446">
        <property type="entry name" value="DUF2457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="442" mass="49321" checksum="8E9E2E62C9ACBFB8" modified="2020-04-22" version="1">MKRLGSEAEEEALEEDDEDEFEDGNDSDNEDVSDEEQDDEDDETDRVYSDDDETDGNETDNEAGFADSDDEDDTEGDFAFWTPGRLGNATIPIPNAEASTYRASANRTASASSIESLNDAAPIREMSRGKRRSRRPRSIKIRPGTPDLPDSTDFVCGTLDEDRPLEDAYVSCMTARKYAKHIATPQDIDPSFPTSDPEDEEDEADDVAKTIESDEHVWMQGKFEDSDSERRRARSRRSPGHSPRRLHSPPPPKQRLRSPPPKQRLRSPPPKKRLQSPPPPKKRLQSPPPRKVFGNDSPKRVHSPPPTRTVYSSGSPSASESKPIKFAPLGSRPGLTHTKSLPRTPNAFCRQYTASRIAAANEIAAKDDGDGPLRGAIDIVKGLEQKRQRRKEKFYQKHCANRARKPQPERRPQPGKGAERMRELGLLMAGKTGTNDPYILSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3A2</accession>
    <name>A0A5N6K3A2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">XPG N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_002114</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPG/RAD2 endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3A2"/>
    <dbReference type="OrthoDB" id="17262at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09902">
        <property type="entry name" value="H3TH_MKT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09858">
        <property type="entry name" value="PIN_MKT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022039">
        <property type="entry name" value="MKT1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037314">
        <property type="entry name" value="MKT1_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022040">
        <property type="entry name" value="MKT1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF32">
        <property type="entry name" value="POST-TRANSCRIPTIONAL REGULATOR MKT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12246">
        <property type="entry name" value="MKT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12247">
        <property type="entry name" value="MKT1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Post-transcriptional regulator MKT1 N-terminal" evidence="4">
        <location>
            <begin position="317"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Post-transcriptional regulator MKT1 C-terminal" evidence="3">
        <location>
            <begin position="488"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8296694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="735" mass="82483" checksum="AA5797997C5FF86D" modified="2020-04-22" version="1">MPLNTGDPLIDTGVVSMPFSDLVNAKIGVEATAYLSNLLKGPADEPLLAALGGHPLALKTHIENDLDKWKENDMEPFFVFEGQSIVGKKEMTMRSLKASISETEQAWALYNDGNPTDAVAAFRKAAAIQIPDLYHILQEVLTARDLEYMTAPFSACAQLAALDRHEEQYIDGIMGSQELLLYDISDAVIYTPSSADWENKALRGVVRSDLLKKLNVTPDMLSDALLMTGTSFLPPFPPLQDQTIITRQPYTVGDAVNLLRTSEKSVSATCAAFSDILNVRDRDWLDKYRKAKMGIKHCVTVATDGSIHIRDFDHLTGDNHEYLGLQLPAELYSYLQKDVISPRLLNTFNSLEYHVLPTLDGFVSDEYRKLVTESLLPLKETSAALIAPRMHRGFLYKEITMRLWFDDNKKPKLNHKQLQPQTNDLADSWGVKDTDIKSLETKSLQAGKLSFAAITLLDKKDLPPKTIGKAKPTGLKSKSEILSNSLWRLLHLRGYVNDKHELTNWGKALATTLKAIQPISEKYQDVHLIEEAAFLAFELIRFQNLHTRDRHPELIGGPLRGQEEDKANCILISRAACLLKIRHSPIGYTGPLSKNFLSYHSIIKAIRETDRDLIEAIVASMLLSGQVVRNVNQYQGLGRSLPFDTDIDVGFGIAVKTYLDDYIKSDVPKDEKLRMKNAYSSTYLPHAINFVEDLDVAFSFFDALHKGVKTLSDEEMKSGEKKTWDDAKAYLELRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3B3</accession>
    <name>A0A5N6K3B3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3',5'-cyclic-nucleotide phosphodiesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3B3"/>
    <dbReference type="OrthoDB" id="258495at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004115">
        <property type="term" value="F:3',5'-cyclic-AMP phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047555">
        <property type="term" value="F:3',5'-cyclic-GMP phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006198">
        <property type="term" value="P:cAMP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902660">
        <property type="term" value="P:negative regulation of glucose mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07735">
        <property type="entry name" value="class_II_PDE_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000396">
        <property type="entry name" value="Pdiesterase2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28283">
        <property type="entry name" value="3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28283:SF1">
        <property type="entry name" value="3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02112">
        <property type="entry name" value="PDEase_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00388">
        <property type="entry name" value="PDIESTERASE2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="477" mass="51968" checksum="08DB24B019D3064B" modified="2020-04-22" version="1">MRAKGISVGEEREDYFLNGAGGGPMEDNCTALLVRSTRQGWTKGSLLAVDAGVHLSAIDRLLRHYDPLPSERPHKLHSGVLSGLLLPHKTTAANSAHIARNIVGAHLITHPHLDHISGGIISTACPSSKPRKIAGLPSTIEALKNHIFNDVIWPNLSDEDGGVGLVTFMRLNSGGSSVLGDGVTKGYMEVAEGLCVKSWEVSHGNCAGDFPYHNLHAGSESPSSPVPPRRPSIQSQRGYPTPLPSEHTFKSGDTPNLSSTNPHRARAYTSSAFFIHDVASGEEILIWGDVEPDSISSHPRNKQVWIDAAPKIATGKLKGIFIECSYDDSRPDEMLFGHLNPRYVIEELEVLAAEVETYRDHGGLRYRCGSSPSPTSDLTYTQKPTALREREKREPGGRPSSWLSTARKNPGGGSVSCNHSRGYPLKGVKVVLIHLKERLDDGEELKDVILREIKGYEENVKLGCEFLVSEHGMSVHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3B4</accession>
    <name>A0A5N6K3B4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">separase</fullName>
            <ecNumber evidence="2">3.4.22.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_002243</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>All bonds known to be hydrolyzed by this endopeptidase have arginine in P1 and an acidic residue in P4. P6 is often occupied by an acidic residue or by a hydroxy-amino-acid residue, the phosphorylation of which enhances cleavage.</text>
            <dbReference type="EC" id="3.4.22.49"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.49" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3B4"/>
    <dbReference type="OrthoDB" id="10255632at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051307">
        <property type="term" value="P:meiotic chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005314">
        <property type="entry name" value="Peptidase_C50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030397">
        <property type="entry name" value="SEPARIN_core_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792">
        <property type="entry name" value="EXTRA SPINDLE POLES 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792:SF0">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03568">
        <property type="entry name" value="Separin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51700">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C50" evidence="6">
        <location>
            <begin position="249"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="392"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="411"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8296830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="464" mass="51454" checksum="D04FBDD2DA1DF7E2" modified="2020-04-22" version="1">MDADEEVFGFEQGKCELLDIIDSAKANSQSGPSRTGRDAKLAWWAEREELDSRLKGLLENIEKVWLGGFAGIFSQYSRKSDLLARFQKSFENVLDKHLPSRRKSKRNSGPRVTLDSRILELFVGLGDASVDDCDFSEQLTDLLYFVVDVLQFHGELNAYAEIDFDSIVIEINDALRCYHEAARSSIQNEEGKHTILILDKALHIFPWESLPCMDGLAVSRLPSLGCLRDRISKQHKTPSESLEGHYIDRNNGAYILNPEGDLKSTQTTFQASLEALPSWTGIVNRAPSEEEMKYELQNKDLFLYFGHGSGGQFIRSKEIRKMEKCAVAILMGCSSGALLDHGEFELGGQPVHYMHAGSAALVATLWDVTDKDIDRFAGKMLEGWGLLGTNGEKGKEKKEGSGKGRGRGKKDKMGEEERNGEGDGKMSLIEAVAKAKGACKLKYLNAAAVCVYGIPVYIRDQAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5A3</accession>
    <name>A0A5N6K5A3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">dual-specificity kinase</fullName>
            <ecNumber evidence="1">2.7.12.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_002634</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.1" evidence="1"/>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5A3"/>
    <dbReference type="OrthoDB" id="283111at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14134">
        <property type="entry name" value="PKc_CLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000612">
        <property type="entry name" value="Serine/threonine-protein kinase AFC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="306"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="129"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="181"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8297274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="662" mass="74157" checksum="86859C04ACA04839" modified="2020-04-22" version="1">MSTPSTLPPHHPNYGYSHHQNYQSNNPYRASNNLLNGSGRLGVSYTNPTNSSSNSTSSSIGPLAKTTQIPSHPAKKPSTNSPQKSTAMVSSASQAPPPHKRQRSKERQPDWDKFYENGLPKEVIVIDSSESPEPSLDVSSHIQTNNSAVAANSRHAAKKRKRNDAYDPVYQLDPSIDPSPQYKSESGSNSTISTDRTTSAIHTTAATSLGSHSSNGQNGYEAAELTGQKRKRTNTRLQLANEAKRKELEVNGDAFSNYIPPPKPPIKSRDVPVRQVLDHSYAKNSKVDDEDGHYIVVPDTNLTTQYSVLKLLGQGTFGKVVQAKDHLDNGKLVAIKIIRSVQKYRDASKIELRVLSTLKANDHENRNRFMDLLGQSVFDFLKGNSFVPFPNSQIQSFARQLFTSVAFLHDLNLIHTDLKPENILLCNSAYQAFTYSRKIPSSSTTVSRQAAQRKVLLDTEIRLIDFGSATFQDEYHSSVVSTRHYRAPEIILGLGWSFPCDIWSIGCILVEFFTGDALFQTHDNLEHLAMMEMVCDKKLDSHLIQQVNAMAKRNGGNPAQKYFRRLKLDYPTADTTRASRRFVKAMKSLDEIIKDQGRFSRNFLDLLKRIFVYDPSERITAKQALQHPWFKEAAIADDGTEATKIRLQRQSGTYTAPQRQHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5A5</accession>
    <name>A0A5N6K5A5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_001500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FKBP-type PPIase family. FKBP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 6"/>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5A5"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF443">
        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="114"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8297692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="214" mass="24209" checksum="D8F7F8AE7CD79998" modified="2020-04-22" version="1">MIKDIKDTKDTKDTKDIKDIKDIKDIKDIKDIKNEEPSRTQILNYLEETGGGRDKDRYRYRQAGKQLMEHKHQITARIPIQTKYQYRNFSRTNAIMGVTKHILKEGTGESPKVGDTVTIEYTGWVKDVNKGNTLEEQKVTPPPFDSSVGRGAFVVQIGVGQVIKGWDEGVTQMKLGEKATLDITPDYAYGARGFPPIIPAHSTLIFDVELQKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5B9</accession>
    <name>A0A5N6K5B9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5B9"/>
    <dbReference type="OrthoDB" id="203724at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024420">
        <property type="entry name" value="TRAPP_III_complex_Trs85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975">
        <property type="entry name" value="TRANSPORT PROTEIN TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12739">
        <property type="entry name" value="TRAPPC-Trs85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8297720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="443" mass="49670" checksum="7C0A95DE2E901E99" modified="2020-04-22" version="1">MKRHFGLHCHLLRIRSSQCVATDDDSVQLPRCEWVAASEEMAEIQARESQEDPEDSFPCIYESDTTAIKTFIREMVTQSVVPSMERCVATWNDQVASRRRGISGRFMSLSKTLKWSTFGSSSRSTSSNVAGSGSNYDALQGFYRPDSPEALMRKLADYSFMLRDWKLAQQIYDLLRSDFSNDKAWKYHAAANEMAAVSILMMPHSISAKTRTETIDLMLETSSYSYMTRCSAPYGALRCLTLGMELLRVRGGSATGDAARWGARLLEHKIVGSIGDSLYKERVAVCYGTKKGHGAGLWGSRTRKSAMWSIMAAEGWLNLEKPHQSKKSLDDAHAKYGTLKHKDSMFYFFEANEFVQGLETQIENTLYPMTESQATIMPDDLIETTMGEESEAFNSRPHRRSLMGGVAPPPIASLESAPLHGTLIEVEEKDKEKAITSNDFEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5E5</accession>
    <name>A0A5N6K5E5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="6">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">EYC80_001593</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DIM1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="6"/>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5E5"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046355">
        <property type="term" value="P:mannan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02954">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000076">
        <property type="entry name" value="Mannan endo-1,4-beta-mannosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000004">
        <property type="entry name" value="Spliceosomal protein DIB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004123">
        <property type="entry name" value="Dim1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052:SF5">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEN 4A, 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02966">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01410">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="14">
        <location>
            <begin position="216"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAB8297794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="568" mass="63696" checksum="126A93EA6A880412" modified="2020-04-22" version="1">MGSVVLPHLVTGWHVDQAIMSEEERLVVIRFGRDVDPDCMRQDEVLYKVAELVKNFAVIYVCDIDQVPDFKTMYELYDPVTTMFFFRNKHMMCDFGTGNNNKLNWVLEDKQEMIDIIETIYKGAKKGRGLVVSPKDYSTRRRWCIDLGEDRFKGMKRYVNFPKIRCSCIKLHMKSLLTALVSCLPLTTALPLISSDSPIAQPGPVYSFSSSGSNAKVAGRLFNVDGKVEYFAGTNAWWLAHLSSNNDVDLSLSQIAATGYKVIRVWGFGDANTPPPSTNTDPNLIYFQILNSTGAYINFGTDGLQRLDYVVHAASKYGLKLVLNFVNNWSDYGGIAAYTNAFNCSSTSFYTDSTCEKVYKNYVKTIVTRYRSSTSIFAWELGNEPRCHGCDTSILTKWAIDISTYIKSLDAHHLVTLGDEGWFTPADGIGDGSYAYGGGEGIDWVANLKIKTLDYGVFHLYPNSWGYNYTWGNEWIEQHDSVGKEVGKPIILEEYGTPFPYKHIETEAPWQATVLGSGIAADQIWQFGPNGTSVQAEIFGDVNTIYFKTLEYATLGTGHARAMLKKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5G3</accession>
    <name>A0A5N6K5G3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_001576</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5G3"/>
    <dbReference type="OrthoDB" id="3257095at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF1">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8297776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="213" mass="23649" checksum="C0ADA1B9DED7A46F" modified="2020-04-22" version="1">MLTWEVVLFTLQFGLQSGGPAGLIYGFLGAWSGSMLQALVMAEMASMIPLAGGLFNWVVILSPPWCKKFLSYFAGWLTVICWQAFVAETCYTVASLIQGLIILNFPDYDPKLWQATLIFYAIALFGAFINTFLGRLLPRIEAMMLIVYILGFIGVLIPIVYLSPHTPTEKVFKTFQNLGEWDSMSLSLFVGWITSVSSFVGNDGADHIVDIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5G9</accession>
    <name>A0A5N6K5G9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5G9"/>
    <dbReference type="OrthoDB" id="10259640at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="70" mass="7980" checksum="BA39DCD1FA2B0ABD" modified="2020-04-22" version="1">MALLRSLPLPEDEEDNDDDTTRPAKRPKKWFEDDSDDERKVAKRKSRVIEAADEPETLEDLEALAAGLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5H1</accession>
    <name>A0A5N6K5H1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cell morphogenesis protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_001634</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6287725at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025614">
        <property type="entry name" value="Cell_morpho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025481">
        <property type="entry name" value="Cell_Morphogen_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039867">
        <property type="entry name" value="Furry/Tao3/Mor2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029473">
        <property type="entry name" value="MOR2-PAG1_mid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12295">
        <property type="entry name" value="FURRY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12295:SF30">
        <property type="entry name" value="PROTEIN FURRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14225">
        <property type="entry name" value="MOR2-PAG1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14228">
        <property type="entry name" value="MOR2-PAG1_mid"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14222">
        <property type="entry name" value="MOR2-PAG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cell morphogenesis protein N-terminal" evidence="2">
        <location>
            <begin position="331"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="domain" description="Cell morphogenesis central region" evidence="4">
        <location>
            <begin position="1161"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="domain" description="Cell morphogenesis central region" evidence="4">
        <location>
            <begin position="1429"/>
            <end position="1694"/>
        </location>
    </feature>
    <feature type="domain" description="Cell morphogenesis central region" evidence="4">
        <location>
            <begin position="1727"/>
            <end position="1895"/>
        </location>
    </feature>
    <feature type="domain" description="Cell morphogenesis protein C-terminal" evidence="3">
        <location>
            <begin position="1946"/>
            <end position="2196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2412"/>
            <end position="2432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2470"/>
            <end position="2525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2414"/>
            <end position="2423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2478"/>
            <end position="2495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8297838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2525" mass="283087" checksum="309435DF8E3C8150" modified="2020-04-22" version="1">MKNFSPIDIDVTSWTATLKRSHTTNSRSLAHSRDPSSNQSFFAGLKAAFSESSSQPANLSPRFYTGSARGGSIDADAKSHHRNTSIVNGIQRSRNGSFGSSSTSPLSPQIIAAAGEDWADASVMGDSNFSSSASSMTSGTSFSSNTTFVPSRSPSAAENVPSSSTQRNMERGNSNGGRSRRNHSHHHSHSRHHKDELKTVGEYALHVLFTSFIAQAEEKISQCVTLPLEPEPQIEQICGIGVDPAFDQLISALGHIASQKPKPLIDSMMLWRKNKSDAANEARIQLQQSRGNLFPGQIPRRNTEPPHLQQDDLMAGLPTIAARQEFVAQAERRSTASIFILCRVLMEVIGQSTLARITPEMEEKLEGIIFGQLKIADADQLNTSPLKMANWFLFSQLLGVMAEINFDSVTDRFIADLEKSQKDLVVKGPVNRDVEGRMVLVLGGMKHIRLKAYPEDAWDQSCDFMISLGRFFARSHGQQLKYAYCMALDILLLPIAATANTELNMPKWTEVLATIGPRLASMFIKPRHWTVAFPLTATLLCVSPTDTFSTQWLQLVLPLQAKMKEPRTRPVCLQVISRLLWTYLHRTTDTTNTTIKKLEEVMKLVLPPGKKSYISTESSIIEPLIQIIRIIGFKYQDFCFRTIVFPLINADLFASGRELKVEQLEPEKMVVGIRAFLAIMSDLEKGEQGCPPFPQHYSPLPVFERMPTSPIMTAPRSPITPSLVVPNREDRLSRPVITNALGDIAKEYYAKFCEILGKITIICDNTFGGQAVLDEKFNGPIPKTPLAESFNFRRDDHLVPSEQKQGFYELLHVAVQALPRCLSADIPFNILVNLLCTGTAHVQYNIAESSAQSLKSIARQSHAQPVTIGFARFIFNFDDRYSTMSDGGMLGPGHIENTLKLYVELLQIWIEEIKNKMKDAALDLSEDGSADKRGVQLDLSGIWAHVDEVESHGLFFLCSQSRRVRAFAVTVLRLITEFDTALGKDNVRLIHILEGDAKGVMDFNDENLSVAERSRLQRGIQKTDPSGRNESDLIELCSSDVSYDTTLWFKIFPNLIRISYDRCPFAVTLGRELICNRILQMYRGIVILSEANRGPQYGYDSGSGRLSSRSSTTPPEVLIEQWKLYLIVACTTLSDKGGQQQSSPQILQHYRKGSKPNQALEKITSARTLFKYLIPLLSVGPASIRDAVVVALGSININIYKTLLEELQGVVSRCNDEARARIHQRSGSNPRRNRRTDLLRTEVTHVYKLTSSFLKEKEIYEDDWILNNLVIYTKDLKIFLMDGEVQLDWEFQKLRRHYCGLMEELFEGINLTKDPSRWMTFESRKSSFALMEDWCGYSPNQNQIRQREDNMRQSMISQQSLGERGVVTAAMEIEKRNLRTAALSAMAALCGGRVSITTESGANLQFDIRRMLSWVDTIFNTGSDRMHIIGRRALKNLIVHNKEFPYLLEHSITRCYLAEAAKVLQSYFGVVTEVLIEYPDYPMPFWRLLGIGLYTLGSELSDIRIKSARILRALEERQQRSSKIQDFDISISDKTKAVYKLAQFEISKRLSANHSELAFLIFSEFTMYFKELQAGPQRNMVAAILPWIQIIELQIDPNGGPTAQSYVLLANLFEITIRCSSTLHNEVQALWQALATGPHAGNVQLVLDFIMSLCLDRREQNFVEYAKQIVVFLSSTLAGGKVVEFLLMQITPKAMVPNEKREFLPPPPDVGKLPYMAELSEALPIGNKQTGLSLGQLSLILLVDLMVSPVQIVAENVPLLLQVVTVLWDHYIPLVQEQAREMLIHLIHELVISQIDDESTTPSKNSIEDFIESIRRHDPKVIWHYDDNSGKVYDQENKVPPGMELLASEVVRDFEVKYPGIQEQWAKLSLTWATSCPVRHLACRSFQVFRCTLTSLDQPMLADMLIRLSNTIADLENSTQLFSIEILTTLRTLIRKLEPADLLTFPQLFWTTCACLDTINEQEFLEASHMLEELLAKLDLDDRSVRGLLAEGRPTSWEGSFGGIQALVYKGIRSSDCLDMTLATLNKLVKLPSDELIGDDSRLLFAVLANFPGFLHAMDQANIDQQSIHTATILASVAEAQGCSTIFRALSGFAASRYRSSKDFLAQLVSALRESFFPKWEFRSLTFVMGSLTNSIPWFKLKTMRILCAIIPDIDMKKSEIASHGPDLISPLLRLLQTEFCMEALEVLDQIMTMTGTPMDKHHLRMSMTRSSSRAMRKEYDNTQSLFGIPEESGWSIPMPAKQASITRSNVHAVFYMCQSTKNTDNEVAATPDVEFHVDDFQYGYFPPAERTETMMSDEARGDGNIGDLMMKLDSLDDFFEDSLQSPTSDGRSSRTITEAGFSSENFDSGAAQLYDEQTLPILHQSLTHSATNSTFQNGFADLRPSRESNNAMTPTAFNLVPTSRPSLHARALTSPSASSGNPNMAYMSDDDFSEDVFSDGEDDRATTSGEGSFFLENMIKPLAAGTRLGMRRLTGNRSRDSERVRDSIRAERRGISQPPRSPRVPKVPTAYLQPQNPLSPEEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7D2</accession>
    <name>A0A5N6K7D2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7D2"/>
    <dbReference type="OrthoDB" id="5416983at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="526" mass="57124" checksum="13EA1D735F9AAB7D" modified="2020-04-22" version="1">MSHSSAHPGPIGPPGANRGNGPYQANRGRDQYNSRPPPIGPPSVNKAPQPSRSYEEEQRRAVARSVWGGVSDRISQEDAILHQQQEELERRRGLEAAGMIENLSQPTYEDTWKQVVLNEDGTRSNTKNVSTTFIEGGSSSTSTLTENMSRGNARPELSRPQYSNNSWPSGQETSAANAHRESKFFPNNHRDVRLEEMNGHGFERSSSPSPPPPTMAGHPAYDSDFARPHVALPPPLPVVRLPPPVVVTPTPPPRPQSFAAAAAAPAVPAISQIPGLAARHGLTRAGSTSYDIRRGPTPSTQTGEWKDKIDQLFGKKSPPRTHALAVDSSSRRVFDHSLEPQASATVSLPGSINDNLIEEEELLDTKPAAEECFEEQEMGSLPVIKIPQIAPENAFQPATAPPRNIPRRFLISDTTSADPIQFPTETSNNTSVLVIMLPGQEKFKSIHFTAFHARSNPRRGRGGSRQTSSTHPRGGRGTRDVNNGPSSTPRDTQSPNPSNTSSRGRGGRGFGNNSNWNRHVTTPIHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7E0</accession>
    <name>A0A5N6K7E0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_000870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7E0"/>
    <dbReference type="OrthoDB" id="191364at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009092">
        <property type="term" value="P:homoserine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF11">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="63"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="248"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="305"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="257"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8298695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="549" mass="60373" checksum="7C945BD5E23F2176" modified="2020-04-22" version="1">MLSRIPYNKIRTQQQPENPFASLIPDQTIAIIPSFTLESGETLHNIPLAYSTRGKLSPNRDNAMVICHALTGSADVSDWWGPLLGGPGRAFDISRFFVICMNSLGSPYGSASPVTCKNGDPKNERYGPEFPLTTIRDDVNIHKLLLDDLGVRQVAAVIGGSMGGMLVLEWAYFGKDYVRAIVPIATSSRHSAWGISWGEAQRQSIYADPKYDDGYYPFSDPPTAGLGAARMSALLTYRSRNSFEARFGRNIPDASKRQTISEGQQPTTPSDIHRAIHNDGHRQTRSPISSRPGSSAAVPTLASENITAHGGNPANFTDPQFHGATPSSSPPPQRPQAKRKSTSHYFSAQSYLRYQGEKFVKRFDGNCYIAITRKLDTHDVSRYRVPADSADPIAEALSQIQQPTLVLGIESDGLFTFDEQKEIAASVPNARLKKIESPEGHDAFLLQFEQVNQHILEFLNEVLPDIMEAPGIEGVEAEGGVGAVTKNNGASLKLYTIFTCYRFRFLGSSTPDYIHSTYFILRLRCKILTLGGRKVDKGSQERDDEGGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7I0</accession>
    <name>A0A5N6K7I0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_000852</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7I0"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14125">
        <property type="entry name" value="STKc_CK1_delta_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000159">
        <property type="entry name" value="Casein kinase I hhp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000538">
        <property type="entry name" value="Putative Casein kinase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="12"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="306"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="318"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8298674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="355" mass="40759" checksum="FD37E4D3BAEF110C" modified="2020-04-22" version="1">MTTMDLRVGNKYRIGRKIGSGSFGDIYLGTNIISGEEIAIKLESVKAKHPQLEYEARVYKSLAGGVGIPFVRWFGTECDYNAMVLDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEYIHAKSFIHRDIKPDNFLMGIGKRGNQVNVIDFGLAKKYRDPKTHFHIPYRENKNLTGTARYASINTHLGVEQSRRDDMESLGYVMLYFCRGSLPWQGLKAATKKQKYDRIMEKKMTTPTEVLCRGFPNEFAIYLNYTRSLRFDDKPDYSYLRKIFRDLFVREGFQYDYVFDWTVYKYQKNAQQQIKPQEGDKASPAEGQTSAQATAGNTAGRQRKTVTPIQQQGQAPEGTGHYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7J7</accession>
    <name>A0A5N6K7J7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THO complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_000869</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="29024at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040007">
        <property type="entry name" value="Tho2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021418">
        <property type="entry name" value="THO_THOC2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021726">
        <property type="entry name" value="THO_THOC2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032302">
        <property type="entry name" value="THOC2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597">
        <property type="entry name" value="THO2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11262">
        <property type="entry name" value="Tho2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11732">
        <property type="entry name" value="Thoc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16134">
        <property type="entry name" value="THOC2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="8">
        <location>
            <begin position="67"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 N-terminal" evidence="7">
        <location>
            <begin position="791"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 C-terminal" evidence="6">
        <location>
            <begin position="1153"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="495"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1480"/>
            <end position="2355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1480"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1557"/>
            <end position="1570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1572"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1632"/>
            <end position="1699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1781"/>
            <end position="1798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1806"/>
            <end position="1824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1850"/>
            <end position="1870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1871"/>
            <end position="1880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1892"/>
            <end position="1907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1941"/>
            <end position="1954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="2002"/>
            <end position="2019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="2055"/>
            <end position="2073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2105"/>
            <end position="2117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="2131"/>
            <end position="2147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2174"/>
            <end position="2241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2256"/>
            <end position="2287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2302"/>
            <end position="2355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8298693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="2355" mass="261309" checksum="A0C506B6ACB97BE8" modified="2020-04-22" version="1">MAPAGKRKRNDRNSVDQATRATPTPGPMSPPPRPSSAAQTPSQTPTANDMISPSWNPEPAPFDYVFLTDDQMSSWNTTGRQQVVEKGIQARQDEDTMDLATVFQEFIRATFDGRIDGADAGNCIKEILGPDTSPADDTPGTLEPQTLFLDSLSMMCELEDLKSPNAALRAFVFSTGIPAPILRQKLDATLLLNLGLTRDTFIRMGIRQATHLLYRQANYNLLREETEGYSKLVTELFTTSGSEPPSSEVVEDAFEKVKGLIGTFDLDVGRVLDITLDVFAAVLIKHFRFFIKLLRASSWWPRSGNFDQVTRCGGLPPWALPSAPGWTSTDEEEEIAKSQRLERDKLFWDRAREVGIEAFFELGGRQAVDAETKERFLKEDDAKLDADHLWIKATGTYPPSGNRTAAQLLGFKLRFYASAARDNEDILPANLIYLTALLIKIGFISLKDLYPHLWPLDEDMEAVRDVKMKEIEEKEKASRGGTMNALMMAGALVDDTLPNGGRTRETAATKTDTSGKPTAEVDDKDKLDEPSDQKVQLLTCLLTIGAIPEALFILGRFPWLPEAYPELLDLIHRILNHSIQHVFDLSRPSTSMIPDCPSKKVIDPDQTGMPKGSIRLLALPPRKQLRWPFPDKYDTNDNNAYRFYWDEWADNVPICQTVDDVFTLCGSLLNISGVNIGKDAPLLSKLARIGTQSLAEDHSTHNFDRWQDLLKRLLVPALSMTKENTSVANEVYGMLRFYPISIRYSIYAEWFEGQISRLPAMRAAFAKTKSETISTMKRISMTNLTVMARNLAKIAFASPGVVFSVALGQIEAYTNLTEVVVECGKYFTDLGYDVLVWSLLSSLGGKDRNRNDAEFALLPSRWLLALSRFSGKAFKRYSIMNLVPVIQYVNDQLHRGNSTDLVILKELISQMSGIVPDTDFTDAQLAAMTGGELLRRQTLINLQDKRYESLKTAKRLMKGLTDTKLGGQLLLSIAQHRQSAIYNVSDDEAPIKLLATMIDDTQMILFQFLDLLRSNLSIEEFDNLVPGIPELMKDFGLDPTLAFMIGRPSIAHRISKLPSLNSNGSVKSPPSMAEALAPEVDAEGDVGMSGDGQNTSIQELPTEDGIAKDDVQMSDAKEVVSPSEVAILEADPLHELLLPYINTVEDVLPEGSWAFLTSEFYVVFWSSTLSDLAIPSHSYEAEISRLLKEQGDVMKDRTDMTRAGMAKKEETKKLLATTRDNLLTEFGKQVGAFSGKKNRLLKRKNLWFSNVKGDLVSDSFLERCLLPRLLLSPSDADFSFRMIKFLHDNGTPNFRTLSLYGRLFRSNRLRSMIFTCTVREAENLGRFLRLVLTDLARWHSDQAVYEKEAWGTSKNLPGFAKAIDADGIVKGLLEHDGKVGFKNILYSWHQKLNGALRDCLEGTEWMHVRNAMTILKSVVDVFPAVNFMGNNFVKQLETIAAREKGIREDLSLAGNAILVQLKKKSKSWVMVQAFGYSLESPVQANSSPTPDASRQGTSTKTNLKPTAPEFKPQSRANSMGVSTPKLPATNEVEDGEVDDAKLASAAGKGNRFKETPSDSTSAQDRVSSAPNEGKKSEILLRREKILRENAARASTPNSAPANIPARPDIQRNMPANHNLPNRPDAPIPGRQMMDRHSGRNDDRRDIRDPRMTELVRDRTRDRGREFPPGDRRALDTPPRDFRNNDRTLNNEHERSRADPSQRWNVESGRDGTNRAPSNGYRTPDNGGRLSREAPVPPPKPSVVSDRGPAINPERLALVNPERQELINPERAALISGGNEPSRSDSPRRLRDDARERSSRQNSPPPRRHDSEKDHQHPRRDDRPNRNAPVDPHITPRGRADDAVPPPAGPRGERPADRVPDRSAPPERLRESSSFQQSQSSPRPLDLDHGRLNRQQDPNFGRLNQQPDIPSGPRDRNRGNNRMTNVPQGRRDGRLANAPADIPRPPSPDKQPPTGPSGGRHPRRLGPGQIEPTSSAHAALPTTPVTSAPTSGVHPDRLKHLGPQATQQPVQAPPVATAPPSGMHPDRVRSFGGQAAAANIPSSHQENTRSRPTAPPLQTQVAPLGPKSQNSPISRMNGAPTGPASSNERAPRGGRQPNLINNINRMLEETKHPQGQERRGRRQGGQPQTPISGPPTPILPPPPPPGLPPTQARDSGRDLINPARADLIGNSASGNDERGRGDRGERGSRNDRSTRSRRTSPSDRNRDQKRGGPPEEERPSRGEHRSRGGDRESRDADRHSRGDAGANRDLLTGNGREGGRGEREHRDRDSSRRDNHGGDRDSQRDQHDAATGSGNWPNPPDNRGGERGDRRNQRSDRSDRGDRDGRGMRDDGGSGRKRRSDADGLREGGHDKRPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9H3</accession>
    <name>A0A5N6K9H3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_000058</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8299808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9H3"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17966">
        <property type="entry name" value="DEADc_DDX5_DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="12">
        <location>
            <begin position="130"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="161"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="9">
        <location>
            <begin position="130"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8299808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="414" mass="44011" checksum="D721F31750209315" modified="2020-04-22" version="1">MSYGGGYGGGGRGGGNGGSNGYSGGGGGGYGGGRGGGGGGNVNGYSGGGGGYGGGGGGGGYGGGAGGDRMNNLGANLQKQQWDLSTMPKFEKSFYKEDPVVAARSEEDVAKFRAQHNIAVQGPNIPKPVETFDEAGFPAYVMTEVKAQGFPAPTPIQSQGWPMALSGRDVVGIAETGSGKTLTYCLPAIVHINAQPLLAPGDGPIVLVLAPTRELAVQIQQEITKFGKSSRIRNTCVYGGVPKGGQIRDLAKGVEVCIATPGRLIDMIESGKTNLRRVTYLVLDEADRMLDMGFEPQIRKILGQIRPDRQTCMWSATWPKEVRALASDYLNDFIQVNIGSLELSANHRITQIVEVVSEFEKRDKMTKHLEKIMEDKDNKILIFTGTKRVADDITRFLRQDGWPALSIHGDKQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9J1</accession>
    <name>A0A5N6K9J1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_000075</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8299828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9J1"/>
    <dbReference type="OrthoDB" id="413460at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18000">
        <property type="entry name" value="DEXHc_ERCC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="433"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="47"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="224"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="100"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="226"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8299828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="635" mass="71566" checksum="5BFE8087AECDA9F8" modified="2020-04-22" version="1">MDSSTKSRDTHDHSNHIKSESMSPPPQNIRLHREHTDTIEEAAAAVADEALLSDSDADTKAQPQDEASALAGLTENVRNQDDLERDITNQANQVMIEQEDQRDQKRIEKVENSIEKLESQKHTQERRLNGLSNNPLMRQRCADEISRIKTEISDLKKDVADIQKRIDERHQYDDSHPGAEVASASRRMPNESQREFLIRTGKITPFQQDSAAATDHVQSALSDALMDAEEKGDVDEPSDNTAEPRSHQNLRLPGFGDVADSTISTTEHEFGLRPRKKRLVNGASAHVSSTRSPSADDDTFTPEHSADEEEEFDDEDDEEALMTARTTTRKRSKPSKARTDEAQSLAGIDDGNEDMFQARLAGWVEKRSAARRQHLEHNPGNEEDLAAQNSSEKEWFKPCPGQPDHQFENGLKLPGDIFPALFDYQKTGVQWLSELYNQQVGGIIGDEMGLGKTIQIISFLAGLHYSKKLTKPVIVVAPATVLRQWVNEFHRWWPALRVSILHSSGTGMLNVKNEGRLEDEEDDILYGQTTKKAPKSQKLAQKIVDRVVKNGHVLVTTYAGLQTYSDTLIDVDWGYAVLDEGHKIRNPNTAVTIYCKELRTPNRVILSGTPMQNGLIELWSLFDFVFPMRLDWRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9P1</accession>
    <name>A0A5N6K9P1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_000088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8299842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9P1"/>
    <dbReference type="OrthoDB" id="10428034at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="87" mass="9877" checksum="D04D25CDBD8180E3" modified="2020-04-22" version="1">MSGRDRRNGEYGVITISINSVDFGENPVGTKFSIYGLEINVKKKLPTYRSIVWNRLVLCSVRLANLRIFQLYTTLEVAGTVYITEMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9P2</accession>
    <name>A0A5N6K9P2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8299907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9P2"/>
    <dbReference type="OrthoDB" id="5552418at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="381" mass="41592" checksum="344BE1C0F4E2654C" modified="2020-04-22" version="1">MDDSHRRRRQNEPPFAAQDPRYAQDQSQGRGIPMSMSDRYRSAATAASPSMNRGVGPTPPYNAGYYNDPSSTPSFPTGIPSNPLQYPPTYPSDQRQQQSFSDYNTGIMYPNVTQQNPQNNGYDSQQFPRQPAAMQMLPDVAAPYLPNDPSNTPGTQQYASSNSSTPYQHQQQQQSPGDRATLISQAYPSNVGLGGMTQTSATADNMDTGNLQGQGAGGMEEAYSIYQTALKQIFKNIIDLRLSEASSSLLEVSEWLLGHVAELDEVALHGDRVRLWNEFNAAWLGIFTRQQDFLQSGQRTQPPQTLMSLEAIGKMGTNLTRLCDSVEKYGLVDYQYGVGEAQIMDILLSCQKAQEDFEASGTSGGGPSSSNGNSNVGRAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAX7</accession>
    <name>A0A5N6KAX7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Spindle pole body-associated protein cut12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAX7"/>
    <dbReference type="OrthoDB" id="5383703at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="25840" checksum="9FE36506AA1E90FC" modified="2020-04-22" version="1">MVARYEKEIARLREAVHESVYEDGTEFGFDLFRTRSHPTEKTHTFASNIPVLSNSIARPSKTVASSKPTHFEVPPEDTQRSSHAALSEITNFAKTEQFAFQKSKKVDYTPLAKRFADLSLDSPDIDLQTEDPSLPLLRTRTSHERCLASPRPKIFNIPSSPPKATVPRSRATNPLKSNNERAASHPITIASSRRSSPSKCVLPPDRVAAAKARLAQKNAEKKRAQALGADSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAX8</accession>
    <name>A0A5N6KAX8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GDP-mannose transporter</fullName>
            <shortName evidence="7">GMT</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_000534</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Golgi apparatus membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cytoplasmic vesicle membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAX8"/>
    <dbReference type="OrthoDB" id="5547497at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8300350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="386" mass="43297" checksum="A4256FD178DBA868" modified="2020-04-22" version="1">MAERSTDLSASVSSASSDADRFDDKTEKRALMGSQDEEYKLRTPEELEDIEGDIERAELLAPPPEEKTKAPESSVRSAVIWMVVNTLATIGIVFTNKAIFSDPSLKLAQLTFAAFHFTVTWLTLYTLSRPRFAMFTPKRIAVRDIFPLAISMALNVILPNLSLAFSTVTFYQVARILLTPTVALMNFVLYRATLPRNAIYALIPACLGVGMVSYYDSLPAADANIKTTSTLGVIFAFTGIFASSLYTVWIASYHKKLQVNSMQLLFSQAPLAAFMLLYVIPFVDTFPVWGEVPVNRWVLIFMSGLFACIINIWCFDRNCWNYCILCGDDQTQKPTQKIDEGANYTTWSAFTPSHIYYHGRTANHSHHLWILEPDKPLRSVSPCSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAY2</accession>
    <name>A0A5N6KAY2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_000533</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAY2"/>
    <dbReference type="OrthoDB" id="331544at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000304">
        <property type="entry name" value="UDP-glucose 4,6-dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="52"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8300347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="435" mass="48607" checksum="641B79F4BDB2B16A" modified="2020-04-22" version="1">MASNGTSKGPPTPSSANGEQNKFFEDFGVWKEAPILTGSTKFTPLPDVKNIMITGGAGFIACWLVRHLTLTYPDAYNIVSFDKLDYCASLNNTRALNDKRNFSFYHGDITNPSEVVDCLERHNIDTIFHFAAQSHVDLSFGNSYAFTHTNVYGTHVLLESAKKVGIKKFIHISTDEVYGEVKDDDDDLLETSILAPTNPYAASKAAAEMLVHSYQKSFKLPVIIVRSNNVYGPHQYPEKIIPKFSCLLQRGQPVVLHGDGTPTRRYLFAGDAADAFDTILHKGTMGQIYNVGSYDEISNLTLCSKLLTYLDIPHSTQAELHKWVKHTQDRPFNDHRYAVDGTKLRQLGWDQKTSFEDGMAITVDWYKRFGERWWGDITKVLTPFPTVTGSEVVGDDHAVEELKEDIVVDADDNTVLGKKRKLNGVSSGLEQTVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAY3</accession>
    <name>A0A5N6KAY3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAY3"/>
    <dbReference type="OrthoDB" id="69928at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="313" mass="33999" checksum="FC34E295827F137C" modified="2020-04-22" version="1">MPSQPTKPTSTTQNYKNSSGENAVASDSLGIMDTEMNRMVDDLLEPASLAPSDDTSYGMNSSIANAIFPPIGSERTRLSRLSTGNQITPTKAFPSLPGIWGSPFTPKPNELRPISPEKISSSVGFPSMNYSTNKDKLAAAAALDSMTGMQRRVSNGVATNARRQLSSFETSKPINQILQESLAKQFEPMSLASSGFSSNSSIYANNSPPKAYYGRTLDRPSLSGHDSTVYPGASDFERNTMLQSSFWNASQTNNDSYKHTPPARQGRQALISKKFLLLRSRGPYQESLAESISALLIVEDRKVNASCTTSFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAY6</accession>
    <name>A0A5N6KAY6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">prephenate dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_000490</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>prephenate + H(+) = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAY6"/>
    <dbReference type="OrthoDB" id="3257538at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04905">
        <property type="entry name" value="ACT_CM-PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13532">
        <property type="entry name" value="PBP2_PDT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.260:FF:000066">
        <property type="entry name" value="Chorismate mutase/prephenate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000034">
        <property type="entry name" value="Chorismate mutase/prephenate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000228">
        <property type="entry name" value="Chorismate mutase/prephenate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000112">
        <property type="entry name" value="YALI0A19096p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052741">
        <property type="entry name" value="Mitochondrial_HTD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152:SF1">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="9">
        <location>
            <begin position="12"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="241"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8300291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="599" mass="66274" checksum="1661CE4904B11D6F" modified="2020-04-22" version="1">MQSKTNSSSTPAISFLGPVSSYTHQAALGCFDKEKYNYQPAISISDVFEAVQSGQVELGVVPFENSTNGAVIFTLELLADRHSLYKDVTICGEAYLDVSHCLLGYVSPADSPVMSGTCTPTTSKPSPVKPKTTPQSSLNHIQRIYTHPQAYGQCEAFLGTYLKGVERLDVSSTSRAAEIVKGDKTGTSAAIASSLAADIHRLDILAKGIEDREDNTTRFLVLRKGVDTCATKVNVAAKSMITFTIDHRTPGALADVLDCFRRYQLNLTSINSRPTKIIPFQYIFFVEFEGSKLSDPEGKVAGALENLNKYTQDWRWLGSWGDKLSPGLPFVRRMWSGGSIVFNSTRGEQLCLNNMRAACIERVVDVSIKGNEGDEKVFVNIERRVGLADTGDDPKMSSEESGAIASNTSSVSDQNYIADKRLLRKYLVDKNDNIGQASLVEMRNLVFMREKDAKSAKEERSRPPKILRPTRKPDFDVRIIPSQSLLFRFSALTFNAHAIHLDPQYCREVEGHKDLLLHGPLSLVFMISVLRSQLRPGEMIKRFDYRNLAPLYANEELRVCVGKKVDKNNKYEVWIEGKEGGYAVKGSAVVGPLDNGQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBA3</accession>
    <name>A0A5N6KBA3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_000611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBA3"/>
    <dbReference type="OrthoDB" id="442243at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8300438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="77" mass="8726" checksum="D480BE29515771CA" modified="2020-04-22" version="1">MTRVSRVQPTTLQGDCEGQRSYSFDGGRKKLKTLWNKLITFYKSILKSIPLSSVQTTQSHICLVDVVLIPIDTQDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBA9</accession>
    <name>A0A5N6KBA9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 9">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_000634</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate + H(+) = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 9"/>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBA9"/>
    <dbReference type="OrthoDB" id="5152799at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000017">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.160:FF:000004">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321:SF6">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="363"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="363"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8300463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="392" mass="44265" checksum="FE50F58B3B4F05A3" modified="2020-04-22" version="1">MIGHLFNAPTNQDNDAPVGTSTVGSSEAIMLAVLAMKKRWKNNRLAAGKSTDKPNIVMSSAVQVCWEKAARYFEIEENYVYCTEDRYVLDPEEAVNLVDENTIGICLILGTTYTGEYEDVKAVNDLLIKKNIDTVIHVDAASGGFVAPFVVPDLEWDFRLEKVVSINTSGHKYGLVYPGVGWIVWRAPEYLPKELVFNINYLGAEQASFTLNFSKGASHVIAQYYQLIRLGKKGYRAIMSNLTRTADYLSDSLEQLGFIIMSQKHGQGLPLVAFRIDPKSDKHYDEFAIAHQLRQRGWILPAYTMAPKTENFKMLRVVVREDFTKSRCDQLLNDIKLSCGVLDQMDKESVQKNQEYIKLHSTHVGKSKHNHPHYKNEKHSLQGKSGKTHAIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDB4</accession>
    <name>A0A5N6KDB4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_003313</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDB4"/>
    <dbReference type="OrthoDB" id="5329176at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="44"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="144"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="368"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="404"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8301449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="473" mass="53830" checksum="BF50CEEE1BC4A787" modified="2020-04-22" version="1">MQQPPAWVVASWPKPNYINPETHGWENVILNVVLYTILCCFLVLRIWTRTRLRASFGADDVMILLAMVPTTAFFVLSLLADLKFMWTRHQYDIPLSHVEFGLKMVLIIEVMFAAACTFTKLSMLMLVRRMLTRRSILYSVGVPIPPQDYWRLTLDPQPNCIDQSSTLLLAGVVNTLTDFLVVILPIRTVYSTNLPRRQQFLVSLLFILGLLSCFAGIVRTYYMYVVTQVWDQVWASYPVWISAAVELYIGIICTSIPATKAFFVTYIPKLFSSHTSRTTRTDTDHHPNYNPYFNSKGDPIPYPGFGITSTSKSHPRTLTRESSMTPLNAENSLHDNTVGTSILELASITNTIRGNSNEKHDEEMEIGMVVGTPPSPSFDGRINSHDNSSKPRNSSIPRRIIGSVRRDRGRTRDRDGYGETTASEESSGHTRSMEKEREREKEGGWDIHIGVVKTIEVEEEHIEEEIRDYDTHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDB6</accession>
    <name>A0A5N6KDB6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDB6"/>
    <dbReference type="OrthoDB" id="10254945at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="169" mass="20036" checksum="30E6CE463F4BA2F7" modified="2020-04-22" version="1">MHNTIIDNKLREVQREPIIERQSDYTTKVEWRPGSVLNKVTDISKSALALQRIRNAPGTIAGQHFRRHDRAKLIKGRNLADMVMDLEDLNKKRERTLQKPLQGGEKMQRQRNEAIEKTEKEARRITHMKLVERRFTTEHGRGRKLDIGEDEINKEVKREVEDEWQEDYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDB9</accession>
    <name>A0A5N6KDB9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDB9"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="69" mass="7310" checksum="F862952BB0291CB6" modified="2020-04-22" version="1">MCLFVSSQTIRHPPPPLYSLLSPPFAYSNSIQLLSISFNFISKVNPLALRVAAAASSSSATSITANLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDC1</accession>
    <name>A0A5N6KDC1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_003279</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclease type I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDC1"/>
    <dbReference type="OrthoDB" id="441446at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF26">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024921478" evidence="8">
        <location>
            <begin position="21"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8301406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="143" mass="15288" checksum="850A28B50704EADC" modified="2020-04-22" version="1">MKVQTSAVLLLSSLVPTTYAWGTLGHYTVAYVATNFVSTATKSYFQEILGNTSTDYLASVATWSDSYRYTTAGAFSAPFHYIDAQDSPPSSCGVEYSRDCGSSGCVVSAIKNYTTILQKGTASAANLNIAAKVSINPTFKNNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDC7</accession>
    <name>A0A5N6KDC7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL29m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">54S ribosomal protein L4, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_003290</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDC7"/>
    <dbReference type="OrthoDB" id="270763at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038340">
        <property type="entry name" value="MRP-L47_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010729">
        <property type="entry name" value="Ribosomal_uL29_mit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183:SF18">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183">
        <property type="entry name" value="RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06984">
        <property type="entry name" value="MRP-L47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8301421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="199" mass="22580" checksum="9E56C89A65511F64" modified="2020-04-22" version="1">MSTSTVIRPAVRSLLQLRKAGSTPPAFLLPCLQSSSTTPSCTQSTSFSTSSTYLYPRDMNRLRGVSTQRRTGPRQPLSVSNAKLPQPVLDASKRNKVKVDENHGLYEFFRHKDKPLSTPAEEGSHGRPWAAEELRGKSWEDLHSLWWICCKERNRIATESYERNRLEAGYGDEDSEKRDMTVSFDLIYTLFSSCAARFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDD9</accession>
    <name>A0A5N6KDD9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_003294</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDD9"/>
    <dbReference type="OrthoDB" id="9439903at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF12">
        <property type="entry name" value="RFEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="161"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="452"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8301426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="675" mass="76157" checksum="14C525A7C27C7865" modified="2020-04-22" version="1">MDRMVILTSTEGMSTVSNGRPPMPVYAGANASQHSILDWPHMMQSNGQNNFMTPYNSNHLANQQMQIKQEPYNSNLPNSQMQIKQESSNHGLFTGVYPGASDLPGPDFSNWNIPAPNEPLQQISSQLLNFCLTTHPQLNARSQEIRKFLSADNIKHFLEQFSNFQGHFPIIHMPTFRITDTYEGLLLGMICIGAVYSDRMTSVQVREMMEVVKMVVESNSQVYAVISRASTGDYASESIGSSKSEIEQIAAIFMMQVLFTWHGTPLQREKARREFPLVVSLARRAGLTQPMTSNPFSVLHQNHVNVDAFVAANFDWNAWVEQEKRSRLLYMIFLLDSALVIFFNIAPSFDALEIRLPLPADDAAWEARTSAECADALGLNGPAVSAQKNPEGNRRRKQPEMHTVLKTLMHHSYDMQTGATNLFSKFVLVHALHVQLWTAQKQVSQESGQITASLNSGTNTPLSQNDWVVRSGDQNGSGAPSANNSGRATPVDGQSHQLLKSVTTAFEKWKKAWDEDITVQYPPGSSYPRRFGFCRDGAHFYWLQKCMLSQKLDWQMPSDQRFTHVIQLLKFAKRWASTDTSKRGEEPGSISDIDKDFGVANLTLDMAQLFRPVNAKIDSPVQGRLCYDGCLEEDEMSFGRDDEKYLRLFGWKERGLAFAHAKNKRRKTYLNFTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDE6</accession>
    <name>A0A5N6KDE6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Purine permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_003330</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDE6"/>
    <dbReference type="OrthoDB" id="1641903at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042907">
        <property type="term" value="F:xanthine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006042">
        <property type="entry name" value="Xan_ur_permease"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00801">
        <property type="entry name" value="ncs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42810">
        <property type="entry name" value="PURINE PERMEASE C1399.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42810:SF2">
        <property type="entry name" value="PURINE PERMEASE C1399.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01116">
        <property type="entry name" value="XANTH_URACIL_PERMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="545"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="579"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="611"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="621"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="636"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="647"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8301470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="664" mass="70536" checksum="F367BF9EE4C939E7" modified="2020-04-22" version="1">MTVVGGWRSAFFSSLPLFISLSSLLFGLGLELELELELELELGLGLGLGLEHLQMSVTIDSGPHDGPDTIVPENSSKRSIGERIHSTVRAFTTKDGLVGDYDYAFLFRPNLPFMKKSKRRAPFFGLQDRMPVILGLLLGFQHSLAMLAGIITPPILIAGSAYFDTETTQYLVSTSLIVSGILSAVQITRFKIMKTPYYIGTGLISVVGTSFAIIPLASKGFSQMYANGMCKTADDGTPLPCPEAYGALLGTASLCALLEIGLSFMTPKLLKKLFPPIVTGPTVMLIGVSLIESGLQGWAGGSGSCMSRPTSGDYMLCPSNAAPHPLPWGSAEFIGLGFSVFITIIICERFGSPIMKSLAVVLGLLVGCIIAAACGYFDSSGITAAPVASFIWVKTFPLTVYGPFILPLLAIYLILMMEAIGDITATCDVSRLQVDGALFDSRIQGGVLADGLNGMLAGLCTITPMSTFAQNNGVIALTRCANRKAGFAACFFLIVMGVFAKFAAAITSIPDAVLGGMTTFLFASVAVSGLRIISTVPFTRRTRFILTASLALGYGATLVPTWFSYVFTYTGGNRAKAGFFDAIVLVMETGFAVTAFVAVALNLGLPEESEDEEIESLAGDLGEREAEERELEMRGGSRGYENGNGGLERESFGTSKAEEGKELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDE7</accession>
    <name>A0A5N6KDE7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_003279</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclease type I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDE7"/>
    <dbReference type="OrthoDB" id="441446at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF26">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8301407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="198" mass="21854" checksum="0588FD6A52B328E8" modified="2020-04-22" version="1">MENFDWRNHVDSFTLGRHNPFWGPSGVVLKARRYLKYKRAMYSQAFYQPALYSNIKSVQTSAVLLLSSLVPTTYAWGTLGHYTVAYVATNFVSTATKSYFQEILGNTSTDYLASVATWSDSYRYTTAGAFSAPFHYIDAQDSPPSSCGVEYSRDCGSSGCVVSAIKNYTTILQKGTASAANLNIAAKVSINPTFKNNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFB2</accession>
    <name>A0A5N6KFB2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFB2"/>
    <dbReference type="OrthoDB" id="3554803at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="639"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="639"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="699" mass="76747" checksum="9E7BFB0DC0ED95C1" modified="2020-04-22" version="1">MGIKGSNLLIKKPIPDSVNPVTVLSTMNGASEETVIEWAPAYERDSPTNRLESPPCCDLAPPIMRVSSPAKVYPPDSFAPPKHATSPAKKSLPWLRKPQITAESTPKIGNASKDTRLSKLAGDATASPPYSEFTSQPNSQSSSIVLHLNTPPEHKRSIPSLAPKIPASIPSSATPSYPQPFVVPREDDNIGVADFASLEQLPNQTRAKLANGDTIAQKDIRLLKNHATQTSAVPSFITRAPHFTTQIPVTVQSQQRRGLVLKSSAISEYKKRQLPQGAKTISIPKSAPPNQMPPAASTITSSYVPPSPLQCTQCNVELNTLSDSRFRSNVTSTSGPSIGFEPNLKRKNMRMCETPEAIHCEGCNISMVNLDISTKDVPGQSFKRHVQRDASLYDHDERRKMGTGSNSKQKEPNTSTDEGYYARQSDIRKTAGNAISERIPAPHPDLTKKKSITELEPPQVNDASMSIPIQDTRSRQSSQSTRPGYVHSQVLSYAKTPDIPVLLDTNHKLSVSGSIGDLQNQLTSLERRTRQEKDTKRLFKGLRVATAAACEEGVDKFIEEITGYKVRKMLMDISALDGLGVNTLANVARQTAKKRRADLRRLQMTQITKEERMEGNFERGIGFGDGDGTWKNGLEEAARVREKERGKLSRSQSGERRKNNTSAEKPSRDRAMGLVAGDQGFRLREEAEAAFDEISARED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFB4</accession>
    <name>A0A5N6KFB4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_005862</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFB4"/>
    <dbReference type="OrthoDB" id="2342176at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11618">
        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-1" evidence="4">
        <location>
            <begin position="254"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="136"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="257"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8302453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="317" mass="31218" checksum="C8E66EB3201C53D8" modified="2020-04-22" version="1">MGTPGGKSVVTWAAGATANWTIGEGALHGGGSCQVALSYDSGKSFRVIHSYIGSCPVAVDASADFTIPSDAPAGEAMFAWTWQNEIGNREFYMSCASVTIEGGSKARDAPAVAFSSRPDLFLINLGNGCTSVESTAVNYPDPGPDADVTRSTSDSGSFVGTCGPVNGVASSGSTSGSSSDGNSTSSPVSVSSATAASASSAPAPVASSSTTPISIAINPTGTAASSAASGVAASAPASPPASGKVSRTVRVSTDGICSGGKTCTGSVYGACCSKDGFCGDGEAWCDAGCQSSFGSCGTTLNSTPTVNPKMRRRSLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFB8</accession>
    <name>A0A5N6KFB8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_005721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFB8"/>
    <dbReference type="OrthoDB" id="164921at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019431">
        <property type="entry name" value="DUF2417"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10329">
        <property type="entry name" value="DUF2417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="549" mass="60702" checksum="ECA3DD25B2A03FE3" modified="2020-04-22" version="1">MVSLWGSKKDSDHDSAPGSVHSRNGDSNEHVAAHQSPPQPRYSHEADERTHLLSPSRDGFLSPDDPAVSPYNLWSVRFLRYFTVLFAIITFLWWVLLLVSIFVSPPGMHSRGSGFFDFSYTTLTFGLLLIVLLFFSTPSKAAQVTCLVIAVILLVDMIMIVGVPRLRVEEGWVGIASVVWALLMAVWTIVTDRVVAAGKVEEEERLTGRAENRRTLREWCSVLTSTVILVILAIVTILLSATLILRSRDASLAPPGERYYVDGGKYQIHIFCEGNLTDAKGNKNPTVLFEAGDGPFEHGMLQVATSAFANGSISRYCYSDRPGIAWSDNAPSPFSAGMAADVLSEALARAGEEGPWVLASAGVGSIYSRIFSSRHGREIAGLLLIDPLHEDLLYRLGTPQRGFVLWGRGIISPLGLDRTFGAIFKGRTREDRVFGRSAYQGGKNLKAKLQESLVANSLTKNEVSSARNIQFETTPLALISSGIEVKRNDEWKRKQEDLSHLTNNLRSWDVVNKAPSEVWRTLEGRDIIEKRLKELVKGAADFEIMEQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFC3</accession>
    <name>A0A5N6KFC3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFC3"/>
    <dbReference type="OrthoDB" id="5387895at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="331" mass="37444" checksum="F77D37D828A2882A" modified="2020-04-22" version="1">MLSFFHPHAVADEYQDLFEFAVHNDDVLVPYNLEATLSRLLTKDDVIFRRFEQHIPRERRDMLYLHKMEDKFNESLRQLDEYSASGTLSNWNALTPPENIGFEHNIPWCSQTLIHISDSMSDNLRWRVGMSRRNQLQAAAILIRMLEAVRSRNVDVYPNHSFRRNRPHGEQLTNRNLYLNLLGPQSEDILGRSGFILDCLEILPENVVSTGDFVDRLNRLHADLSSVAFVSPRRLYGNRLGQLVSKLREIHGLPLVSVSPSMPTTSAFSADLNTSYSVGSSSSYAIAGPSSLRVPSSSSRARRGSSTRSTLGKRPGRSASSSDRRGKRAMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFC4</accession>
    <name>A0A5N6KFC4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005884</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFC4"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="70" mass="7989" checksum="E2E4AA3A597FDFC5" modified="2020-04-22" version="1">MALGGVFQGVDLMGKRGRGSKIFPVHSRGLSYNDWGMDIHHQQQQHHQQHHHRQDGTLMRFKEAANLGCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFC6</accession>
    <name>A0A5N6KFC6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFC6"/>
    <dbReference type="OrthoDB" id="5370537at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="722" mass="79952" checksum="A98A63B7F7FAEFA9" modified="2020-04-22" version="1">MSLTPTPKISPSALLRQSNVLSSRDLFEARTPPNAEKPQLLRFRRSVVPMKLEKPAHRAIRHQYLPSVAFRANWEDALNEAIMAGLQGSQEVADGPEPDSVKAVLLETPRTEDSRIVNEFLEQSFIDATENEDRFTGPTYSAVYNPALLHPVFFTENLVSDVDDIHPAAIGYTKLLRLTASVKDWDQALGKAISKSTPRMQRPMAFSFMWKDALKEAIAAGTPKEEVETSIVTVVERDAISNIDSSIDVASPHSVFSGESMTSSPVDICQEDLENVKKLNFNSAVLHPVFFATTLVSAGADIHPACIGHVIMTSASKMTESNLWVSKSTRVASVRSSGMWTLSSSTSTPATRDHVPVGELASTSPRRVIIQRTMKLPTLKFFELWQPTLVSLVSRNWLETSSRSIESRNFLFQTPVATVTSQSDALMWTAKGSSTPDLFSNIMYEPTKRATGTQSSTIPVLESSELFTCQHESKLEIDWLRLSITPTTSMSKEPMMWAASVPTTSLPDLFGGSKSDRVKRAPVTRPFNLPTLISTELFKVNTDTNIDINWLRMSVTEPTNRDTSTQGLKEISIEEPISKEVTIEAPAVGEPTFEELMADIEALTEEQIAELLNADEFSGEADTSTEPIIHEPLVNTHSPVGRLWTASPDAAIEDITGTWKLCHSATIGRPDIFTKSIEPYSQKSSDYTRRDLPRLESSELYMPSFTSNDEIDWLQASSMDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFD5</accession>
    <name>A0A5N6KFD5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005888</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFD5"/>
    <dbReference type="OrthoDB" id="2159384at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="80" mass="8952" checksum="88B540947D7B434A" modified="2020-04-22" version="1">MWIFLRVETEWGREKEKGNANGLLGGPGVDDVLLGDYRDDDDYNGRVPEYIVVKSESSDEVLLHTCLNIWNDTKTPPAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFF0</accession>
    <name>A0A5N6KFF0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_005825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFF0"/>
    <dbReference type="OrthoDB" id="5398396at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="284" mass="31640" checksum="54C35921732872F6" modified="2020-04-22" version="1">MGWFDGASESGRSHSSRHHSSTHSHPGKKHHSTSRSTHHKNSSGLRGSVLGSTSPKSSHSHRERSRSRTRGSGSIFGSGDAKHNSSRGSFFGFNSRSTSHYKRSPRPNYLKSIYQKLRQLLRDLIYYMKRHPVKVFMLVIMPLITGGALAALLKKFGVRLPRGLEKLIGGGNGRGGGNETYEFERSSVRSSGDQRRTFPCAPSFMIRWLLKPIHLHSVYLELANYHPLSNPSASSHITSMNRKPGSLHCHRINRIPHPLSLKRQPSTEPSLVNPSTQNISIALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFF2</accession>
    <name>A0A5N6KFF2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_005899</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ZNF598/HEL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFF2"/>
    <dbReference type="OrthoDB" id="3838338at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16615">
        <property type="entry name" value="RING-HC_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041888">
        <property type="entry name" value="RING-HC_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056437">
        <property type="entry name" value="Znf-C2H2_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044288">
        <property type="entry name" value="ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938">
        <property type="entry name" value="ZINC FINGER PROTEIN 598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25447">
        <property type="entry name" value="RING_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23230">
        <property type="entry name" value="zf-C2H2_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="110"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="389"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8302506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="437" mass="49581" checksum="A47BE301B9A54B2C" modified="2020-04-22" version="1">MATAETTSTADPPSRPRNDGQRGQRGRGRGRGRGGASGDAGGESRHSENRGGRRGRGGNRGASSSQETTNANTNTMNSADLTAKFSTQKKSAKTDETKDADGEAVEAEVCFICASDVEHNAVAPCNHRTCHICALRMRALYKTKDCVHCRTPSPFVIFTDNATKNYEDFSDEDISNTDPNIGIRYESNDIQEDTLLLLRYNCPDPNCDAACRGWPDLHRHVKSIHQKKMCDLCTRHKKVFTHEHELFADKELERHMRRGDDNPGALDQTGFKGHPLCSFCGQRFYGDDELFLHCRDKHERCHVCDRLSNNGQPHYYVDYSSLSQHFRKDHFPCNEPECLEQKLIFFATEMDLKAHQLEVHGSTLSKDVRRDARTVDISTFEYRQPYVQERSRGGSQREQRDGRGRVHNPYVGMNKLSIDKWLCKVRKLGRQELLVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFF6</accession>
    <name>A0A5N6KFF6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_005820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFF6"/>
    <dbReference type="OrthoDB" id="5289641at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39697:SF1">
        <property type="entry name" value="RICIN B LECTIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39697">
        <property type="entry name" value="RICIN B LECTIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="30965" checksum="5CAA3FDFAB439607" modified="2020-04-22" version="1">MAKQRISDNPPDRDISHNLLSHRSNILSGNKGDRTTPAAQSNSSKSANASSTTSVIEVDKIKNKVITFAIFIALLFIYILLKISFNQMECESVSDVDTSTVCGALTPPSTIVNDDNHKNNDKSSVPWPHSTFLIRSVSSGKLLTLQSGAVILAQPGDNRGSSIHWKCTEEKGWLHFQNAASGLYLGHAFHADLICNARRPDGWERFTARTRPEGGYHLLMTHWGNLWKVGINEGKLAKICAGEWGNLTNSEEGEGEGQKYVQQSNLEHRDGYEDLDRNEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFG0</accession>
    <name>A0A5N6KFG0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">T-complex protein 1 subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_005895</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFG0"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000002">
        <property type="entry name" value="T-complex protein 1 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8302494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="34232" checksum="3159B5C21AC1F272" modified="2020-04-22" version="1">MDTDKIKIFGARVKVGSTGKLAELEKAEKDKMKAKVDKIKAHGINCFINRQLIYNWPEQLFSDAGIMSIEHADFDGIERLALVTGGEITSTFDHPDQVKLGHCDLIEEVIIGEDTLIKFSGVAAGQACTIVLRGATEQLLDEAERSLHDALAVLSQTVKEPRTTLGGGCAEMLMAKAVEGAAVKVDGKKQIAVGSFAVALRQLPTILADNAGYDSSDLVARLRSAIYDGMSTYGLDLLTPGGGIADMRELGVIESYKLKKAVVSSASEAAEVTSPQSGQYHSQCPTETRKMSVMKEEKNDDCIMKMQTCSRGFVATIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFG5</accession>
    <name>A0A5N6KFG5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Plastocyanin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_005846</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFG5"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF71">
        <property type="entry name" value="OXIDOREDUCTASE TPCJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="143"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8302432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="223" mass="24879" checksum="DA4F1710F361DD08" modified="2020-04-22" version="1">MQSSHLPTADSQKRNEAIAVQSAVLPNFRWKEGFWLFCQRARRGGSYLVIYIKSEFRNYVILLKYLLDLIMKSAFFSSLAPIASFSLAWALPAIEVVSSALEERQTCANTATTRSCWGQYSVSTNSYVTIPSTGVTREYWLIVQNTTLSFDGVARSTINFNGTIPGPQITADWDDNVIVHVTNKLTNNETSIHWHGMRQLNNSQYDGVPGITQCQISPGGTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFG6</accession>
    <name>A0A5N6KFG6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_005898</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFG6"/>
    <dbReference type="OrthoDB" id="10251073at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10567">
        <property type="entry name" value="SWIB-MDM2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEK-C" evidence="3">
        <location>
            <begin position="5"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="DM2" evidence="2">
        <location>
            <begin position="203"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8302503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="284" mass="31994" checksum="4F3CEC1E4BB9ABFE" modified="2020-04-22" version="1">MSLSPEENSKYSIIIDRILKEGDLSTISAKQIRKDLQAELGFDLSHQKVVFLQFRASNANFYLKDAVKALILERFDEISKHTQDTPDSPPATNGHVKDEYAKDEGSQSPSLKRETDGSDEDEKPKKKRQKQDDDAKLAALLQAQENSRSRSTRGGGTKRSASVKKSKSTPKKKKSSAKVKTTDDSDMELGSDGEPKEVVKKGGFHKQYHLSTALADLVGEPTLSRPQVVKKIWEHIKGHDLQDPSDKRQIICDDKMQLVFKQDKVHMFTMNKLLGKQLYPIEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFH7</accession>
    <name>A0A5N6KFH7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Inositol oxygenase</fullName>
            <ecNumber evidence="4 14">1.13.99.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 14">Myo-inositol oxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">EYC80_005919</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 14">
            <text>myo-inositol + O2 = D-glucuronate + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23696"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:58720"/>
            <dbReference type="EC" id="1.13.99.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="13 14">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Polyol metabolism; myo-inositol degradation into D-glucuronate; D-glucuronate from myo-inositol: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the myo-inositol oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.99.1" evidence="4 14"/>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFH7"/>
    <dbReference type="OrthoDB" id="5151075at2759"/>
    <dbReference type="UniPathway" id="UPA00111">
        <property type="reaction ID" value="UER00527"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050113">
        <property type="term" value="F:inositol oxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019310">
        <property type="term" value="P:inositol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007828">
        <property type="entry name" value="Inositol_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12588:SF0">
        <property type="entry name" value="INOSITOL OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12588">
        <property type="entry name" value="MYOINOSITOL OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05153">
        <property type="entry name" value="MIOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="144"/>
            <end position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="200"/>
            <end position="201"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="277"/>
            <end position="278"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR607828-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR607828-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAB8302530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="342" mass="39947" checksum="C3D09B60805C803B" modified="2020-04-22" version="1">MSLLVMILVRFYQSIYSRKSLNLSHYLSSTMSPSATTEFPNVILAHKGTDGRALEDVADGIEELNRARADIRDLETPSQFDADKDKSKFRQYEEAADHVKEFYREQHLKQTYAFNVKVRKDFAVRKRIPMTIWEAMERLDRYVDKSDPDTDVGQIEHLLQSAEASRRDKRPRWFQFTCLIHDVGKLWGELGSEGQWDVVGDTFPVGCEYSKSIQLYGSLKDNPDYNNPEYNTKFGVYEEGCGLDKLMLSWGHDECLYQVVKDQSNLPDEALYIIRYHSFYPWHSEKAYMYFMNEADYKGLAAVKAFNAYDLYSKNDAPPNVEELKPYYMDLINEFMPGVIYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFI4</accession>
    <name>A0A5N6KFI4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFI4"/>
    <dbReference type="OrthoDB" id="46868at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="104" mass="11653" checksum="661A78C3C0A43DB4" modified="2020-04-22" version="1">MSFESLSERLAALQESNRQARELIGRLETIEFPPGSIALDNDDDNAVLELSAEIAQVLKDQGDDFEILQEEVLSLVAGRPNSESQRQRQVLEEAVERDIAELRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFI7</accession>
    <name>A0A5N6KFI7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MHD2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFI7"/>
    <dbReference type="OrthoDB" id="2015333at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052811">
        <property type="entry name" value="Glucose_resp_signaling"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014772">
        <property type="entry name" value="Munc13_dom-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47263">
        <property type="entry name" value="ADENYLATE CYCLASE ACTIVATION PROTEIN GIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47263:SF1">
        <property type="entry name" value="C2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G02350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51259">
        <property type="entry name" value="MHD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MHD2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="232" mass="26182" checksum="EF8D1F9660492EFA" modified="2020-04-22" version="1">MKQTLTDASMIMVMTRLWKEVLLALESLLVPPLSDKPSTQRPLTQQEMDIIFKWLELLFEFFHARDEETGEAMGVPADVLKSPKYHELASLNFFYFDTTDNLIRTSERMATATAQRAQQQRNRLSAPATLGASFGGLMGSTSMRRSKSIMLSRNLGTMKKAKEEKRKQAQADPSDDMILRILRMRPEATAYLRDRSRQKERLAAAAAAEMIVRQSLASGGGPRFGANNLPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHG0</accession>
    <name>A0A5N6KHG0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_004592</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHG0"/>
    <dbReference type="OrthoDB" id="1706066at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050218">
        <property type="term" value="F:propionate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43347">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43347:SF3">
        <property type="entry name" value="ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="4">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="79"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="3">
        <location>
            <begin position="557"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8303142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="702" mass="77422" checksum="AE880B664A5F8555" modified="2020-04-22" version="1">MYTDKMPFYPQDEVQSQSLSDPQSFWAKQASYLHWHKPPTQILTEKTKTLKSGTEHKHWEWFGDGEISTCYNCVDRHVLAGNGEKTAIIWDSPVTSCKEKISYRELLREVEVFAGVLREEWVNRGDVVLVYMPMIPAAIIGILAISRLGAIHAVVFGGFASTSLAQRIEASKPVAILTASCGIDGAKPPLSYQPFVTEAISLSSHKPRKTIIWQREQLRWENPNKEKGERNWQRLVKSAASRGVEADCVPVKSTDGLYIIYTSGTTGLPKGVLREAGGHAVGLNLSISYVFGIHGPGDVMFCASDIGWVVGHSYILYAPLLAGATTVLFEGKPVGMPNAGTFWRIIDEYKVNTLFTAPTALRAIRRDDSENKLFKEIGERGGLKSLRALFLAGERSEPSIITMYQELLARYAAKGSNVIDNWWSSESGSPMTGIALSPRTALSRTSHKTGPIIPIKPGSAGKPLPGFDVRIVDDSGNEVPCGTMGNIVLGIPLAPTGFRTLWGDEERFYKGYMKRFGGRWIDTGDAGMVDEGGWISVMSRSDDIINVASHRFSTGTIEQAISTHPLVTECCVVGIPDSLKGHMPFAFITLSTPTHPVSAIPDIELEKEIQGLVRRQIGAIAHLGGIIQGRNMIPKTRSGKTLRRVLRELLENEYYGDGGKRVNVPATIEDEGVVEVAREKVREYFESKGREMEEKMERKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHK1</accession>
    <name>A0A5N6KHK1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHK1"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="219" mass="24232" checksum="67AE6F5F098C406D" modified="2020-04-22" version="1">MVKRESATIASLQLTTSQATFGFIRIVLMVKLPYNLCPFICLHSSNPCHHLLLFKLRDYNFSIVPDFWLESATMAKKIKNPMTNPPQNISDSSCDDDGAPIYTPPETEPNDGPSSSTHSLDLSHISEVIQGIQNVRLATDKSDDSAQEPIKDISAKPKKGRRSKAKRSVPADIAVDNVTHTLSTLVVADGGTDDLEQKRQKSKSAKNRNEREKKEETQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHM7</accession>
    <name>A0A5N6KHM7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycoprotease family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004726</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHM7"/>
    <dbReference type="OrthoDB" id="10259622at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="777"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8303284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1211" mass="131469" checksum="30B8CD2102F9A33C" modified="2020-04-22" version="1">MNTKNQIISKTQVGGPPPPLSTNSPSTVPTENPFETIFDEKDDGDSWKDEDISITSPEEQPRPKPSESIATGRVGNPTRSVSRRDRKYSVSKPIREKSKGRQRGIHAKFGIKVQTNFSTHHGPQPRMVSSQQSRPNVFADLATLRKLENVSAHPNGTSWKSLKNTTIGSSPEKVKASALEPRQSQALIVSPLAERRGSSRLTNLKLVDDLSPNDRPIVIGISIPSARLAHHTTTPQTSTSIASTMMENYGHETPTGKGLATPSIVVTPAAQEISAWSPYSTYSTASNVSRARTLSTSYSVASPNDPFKDGAPPLPTIPAALFEEEKKRVAAQQSYFSPDSDATTEWDDEPYSSRVLSSCVIYEEGEHPIIVRSARSVSFSFSDALKVNNHESIDTTAVRPLSEGWWNYITTPFMTRSNTVAFPEKKVSDAPEVPILAVAATKAQESKVERKSWENLFSPLSIKRPTSNASDAWWDVTPLGFRSEKQEPSGLIYRDMRHTVKPLMTTLPFVRSASGDVGDVTLTSITDSSATADYVNASNSTAYYDNSGIPSVRNDSISVNKDNSLSSVADRTKEFGSNNPFVHSQNSNIDLYNTSSMVTSTASNGSEIKTRTLVANTATPPPPPPYTESPKKVRKYRAFFPPSHESNSVPASNLHYPSSPGPISPGMQQTMTSQGGLQLSEVPLSPAYSRTNQNTAYPGPARQTTPTLLIMTQEYLQQMSDKAAIKAAKKAESKRQKNEKEDKIARKAGGLWAGRGCMPKNGCHGRQGPEGRKRRRWYCCIFIGLLLLVILIVGLATTLTRKPKHTVIQSQWLNLTGFPPIYAGLSTVAAPVNIVTNTGCVFPATQWSCALPKEEQASVAPNLPNQPNFLLQIQWDNSSVANATFANVTGNKNLSTRSLVGNPVSAGKFIRDLILKTRQTIAFNPSPPPPSYAEETFLGDTTDGIVSSNKAGESTPFYISFLSTTNTTLIASNSRVKRADSSDTDPNLFPNITTGIPAPSLNADGTAAPANLLPYPIQQPIRLYDRGLPTEHYGFYTYFNRTIFLKSLALLNDTNTSNGEVPDDQNGGALEGEANFRCTWGETRFLVQMWTKMNGTAKLNNATSSTSTSTIIPGQDFSQPGSFPYPITITTDRHGGDPAKKLLYCYSMNDREGIIANSGEVNGENRGFGGQIINPAPSVFSNSSDPSLGGFDGGTGGCSCSWSNFQEVIQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJJ8</accession>
    <name>A0A5N6KJJ8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJJ8"/>
    <dbReference type="OrthoDB" id="5385072at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="244" mass="26441" checksum="F2BA9D7394FFB98E" modified="2020-04-22" version="1">MRLSASEVEGGDSDDDGDSGRILYHRRTGSGRSSVGSGRRGLTYSRQSGASSNAGRWSSGNTPPSERERQNSFPDVAEAGETPVPNRHSTAKDYFEGGDGTRSAGGSISSGERADGIADLNSGDAARLASNSLLKSSISREKSVKNPDELRRRGSVDERTTTMTLGAGRLFIANPDHSDNTRRPAITRGDTFLDDGIHITHISFKISLLWSREPRGKQATAFKRRSIGVSWVTWQYQFGLGYWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJK0</accession>
    <name>A0A5N6KJK0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJK0"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="88" mass="10095" checksum="C20D831E2F5DCCB2" modified="2020-04-22" version="1">MKGNECSIGKGLGNKGFHYCPLYCSEMLREVFPCLNARYRMPLKSERKKPAPAPNHLIIYFLHTLTAPPFCHPPPFHSVNCNNLFYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJK6</accession>
    <name>A0A5N6KJK6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Large-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_005327</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJK6"/>
    <dbReference type="OrthoDB" id="10010920at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="entry name" value="Large-conductance mechanosensitive channel, MscL, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266:SF2">
        <property type="entry name" value="LARGE-CONDUCTANCE MECHANOSENSITIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="MECHANOSENSITIVE CHANNEL MSCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="Gated mechanosensitive channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="184"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8303973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="24346" checksum="9A560EF2AC5AFA75" modified="2020-04-22" version="1">MPRPSLDFDARAASEPLLRTTHAARKHLTSFWDGFVDFAFNDNVLHVAIGLIIAQSFTTLITSLVSSVLLPPLSLLPFLNKNLDEKFAVLRPGPHYGGTLHNHTEVGGGVGEGVEGNGTAVFKMGIEFLYGAGYNTLKQALDDGAIVLAWGSFINKLINFIGVGLALIAARRFSKRHADAYSVPPGKMDEKTFDPHLSPDPYPNNCPPSPESLNDMQRRIKYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJP0</accession>
    <name>A0A5N6KJP0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WDHD1 first WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_005175</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJP0"/>
    <dbReference type="OrthoDB" id="427368at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000790">
        <property type="entry name" value="Chromosome segregation protein (SepB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057646">
        <property type="entry name" value="WD40_WDHD1_1st"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932:SF10">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24817">
        <property type="entry name" value="WD40_WDHD1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDHD1 first WD40" evidence="5">
        <location>
            <begin position="12"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="230"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="328"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="329"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8303801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="406" mass="44909" checksum="11EFCCBAF33EB1FD" modified="2020-04-22" version="1">MASITQINLRPRPAHTSGPTYLSYTPDGTKLVTVGSNNTTRVYKTGSDGEPTNIDDCQEQNMGVDSTNEFFVAGSEDGTVSKYSLDTMSFDKFLTRCTLPVRDIAISPNGEWCAIASDELTVKIVDTNNVNHIMYLDEHEKPAKHISFDPSNNFITLSCTDGMIYIYSLLEDNARLLRKIDGMIRAVETDDEISSKVVWHPDGRVFAAPTSTRDVQVMSKNDWEKQRIFANGHTGDITALAWSPNGAMLASAGKDRKILLWETRTQKIIATYDYANVMDLAWHPTNNLLSFTNSDGEVYIFQNFVPNEHAHLVKLGPQPAPFIHDPLLETSNNSRRPTTNGTKDIPVRGVRRGSSESLDDILDSDVMGEEDDFVIDDDGAGYALGLNSNGKRPAGDVDSYGVSRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJP7</accession>
    <name>A0A5N6KJP7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ceramide glucosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_005366</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8304016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJP7"/>
    <dbReference type="OrthoDB" id="1483400at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008120">
        <property type="term" value="F:ceramide glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006679">
        <property type="term" value="P:glucosylceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025993">
        <property type="entry name" value="Ceramide_glucosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726:SF0">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8304016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="40529" checksum="4A57EE055C2BDABD" modified="2020-04-22" version="1">MVDKLCGFKADGTRATPYKFVHLLPLVVDSLGASTQEEDTEGLLTAGHYVSFTNPLASNISTAPEHESNLDASARIGGGRLEESFMASSHAKFYTAINTVSIAPCIVGKSNMFRRSHLNYLTSTSSDYAPGIDFFSENICEDHLIGDLLWRKQIPEEKAGEKWNKHGLVLGDLAIQPMAGMSVREYIARRVRWLRVRKWTVTLATFVEPGVEPLLCSAYGSFAITTLPWFHENLGMPQTWLAFIIVWLSNVVAWMALDWAVYTNLHSGASIEVDTNTPSFARPPRSRSRRPFIEWASAWLGREILALPVWTWACLGGTTVMWRGKKFRVNLDMKVIEIRDGRKLSIPEIENGRAHSKDRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJP8</accession>
    <name>A0A5N6KJP8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8304020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJP8"/>
    <dbReference type="OrthoDB" id="3546893at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="559" mass="61237" checksum="A33FA140ECB37D06" modified="2020-04-22" version="1">MERHFSESANSDEYSPTLSVCNYYVENISSEVEFFKHARSSLAMKSQVRRHCQNIDEEIISPDTPTETLVSFPPLPPPGSGIEVADASDESDLPEYLKSERPGSGTENSSTLPRLSHTNTTNIRAPSPKRVSFINLPNTRPKSPTRLSQSFISPENNALVLGPRPPSRAKASSPLAIPSTSLPALPLLSTTLPIPVHLTGPRPEPHKSASYSTAMTTLTSNTSSSTRDSIATSIGILRRMNSEISCISAGDTDSSPMVPGIGLDWGDRRRVSRASRFYLSIGSPIDGAAVPNHRSSLSMLYPNTYSAYSSSYFPQGNDSSTSVNSLGERRQSRSDLMNPNYGNLQEILEDINASREGSQGGSTRGSSPVATGRHGLNVKEKKLSLTNLTILPDGGIGYMMDYEDEDDTIIEPLSLSRTNANVEKETSTNKESKETRWSDAMVKPLTKTTRRESKMEHPSPKTPPKWGWSQAVNVAKERLNRSPTRDKENTVDADHWNMGRDSPESLGLYDQDGFLKNSPERIKADEAKRGRGRSATVNALSVDAMEEKRSERLSAHIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJQ7</accession>
    <name>A0A5N6KJQ7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8304030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJQ7"/>
    <dbReference type="OrthoDB" id="3012298at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="14505" checksum="17D10C1F6E80CE6E" modified="2020-04-22" version="1">MMMMRGWPAHKVVVGMVTNPGNGNGWVPFEILREVLLNLKLRYPTFGGVMGWEYFNSLPGDRERPWEWAAWMTKILDKLPAAAHSITSASTSAVVEKQKPLVSSNVDDDLTGDAPLPSEFEYHSEGVVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJQ8</accession>
    <name>A0A5N6KJQ8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005374</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8304026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJQ8"/>
    <dbReference type="OrthoDB" id="2014201at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8304026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="201" mass="22673" checksum="BDAE39C38D6ADAC9" modified="2020-04-22" version="1">MSHQGQRDLPDFLQNSPYLPVINFDIDEPPPVKAAKPSIAQILRSRPVRTAIPIVICGLIILLLLPRGTRKARELHLDYKTPACLKQAPIVVEPLTGKETGIEWGKYAYITYATSKNHLCNALLLFESLNHLGSKADRVLLYPQLWKTEWAEDANGKGVETITEMLIQARDQYKVKLNNVEILQHRHATAGNEFYLHPTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLN0</accession>
    <name>A0A5N6KLN0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sof1-like protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_004091</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat DCAF13/WDSOF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLN0"/>
    <dbReference type="OrthoDB" id="10249065at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000657">
        <property type="entry name" value="U3 small nucleolar RNA associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007287">
        <property type="entry name" value="Sof1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051733">
        <property type="entry name" value="WD_repeat_DCAF13/WDSOF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851:SF0">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04158">
        <property type="entry name" value="Sof1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="30"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="73"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Sof1-like protein" evidence="8">
        <location>
            <begin position="106"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="168"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="184"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8304734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="197" mass="23255" checksum="E0B300F6E6CDB30F" modified="2020-04-22" version="1">MEAFNFAVANEDHNVYIFDMRKMERALNVLKGHVAACMDVEFSPTGEELVTASYDRTVRLWTRTKGHSRDIYHTKRMQRVFSARWTPDSKFILSGSDDGNIRLWRANASKREGIKSAKQRTALEYNEALSERYAHMPEIRRIKRHRHVPKVIKKAGEIKAEELKAIKRRQENERKHTKKQFSNRRAEREKMILANEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLS1</accession>
    <name>A0A5N6KLS1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLS1"/>
    <dbReference type="OrthoDB" id="3451301at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="707"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="718"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="735"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="873" mass="101667" checksum="7247C803B6FE2301" modified="2020-04-22" version="1">MEKSKYHHSITGKSTCQTINLSKGKKDECSWQSSTLTTCLPPAGCIIHDIHDEHQNTLMGNNMMPYPTNRAVPQPETPIMTPYLPTEIIHSIISHSNDLQSLKNWALVSWKYNDIAERILWSNITINTSQFYDPAYPSDGQDPLQILRYESLERRMKRHLRPTWMDMDRRDYRVPSIVSRLPMIKHFALRTVWDIDSRDLPQSGSREDWRILELYQELFPAMQNLCTLRIDGEVNRRTWDLLLVLPSLRELRIWRTTTVDSQALLERCYSPDSMNRFSQREKQKLVEDKVLNFEGLSRLRTFEIGLLSPMESAALGSEVRKSNLEVLHIAVTRDNKSYDNQGMHTLSRFWENLVPNEIDDSSPVAQDLDYGFPASMRELVLEDDAHRDIAPAKIVKQSLRRCRENLTRFYFDFLDEPLLASVLQSSTKANPLFPRLTHLHLPWVQSERHEFDHPRTMSKTMIAFIESHKPTLQVFQLLNAAEDSRLLKYENPLNKALKEWMSIKEIRLDSEHTADHYSNVPRGQEWTRPADFLSVDGGGYWGEDLRRARLDRFDLTNIEIGFKSYRAWHNIKVLVLNPRLLWNYCLLQDPHDISSPRLRKIDRDHLLGMKHFAESECENKELAERISRKMGPNLRVLSIRECRFWIERYGGPIWHFGDALADPEQRRQMNRILDRRDWDFLSERSTTDTQEAANTATFLRNDMYSPVQPVTEPVTRPISPTSTSIISDAISESESSSEDEDEVMDSETENEDEDRSESMAAEMDGDTEIHIRTPPYLSPLDTDNSMDVDEDGDGDVFMFLLPSEMPWNILSSPQSHTGRELLASIRIEMGGLMSFFTNYWFAGRFEIMIGEFRDVCFTFMRYPSHLTFSMEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLT7</accession>
    <name>A0A5N6KLT7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004113</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLT7"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8304763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="99" mass="11337" checksum="42D7EFE9D1E3AD99" modified="2020-04-22" version="1">MKPQAAEIHMISKHHKAPSHKNSFLAPYFILISTFPSSLLKIQYQAQHPNLSTNPPKHFHYQISLQTLQGFPSKRHPNKTILGDMHTYAMRLPVRGAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLT8</accession>
    <name>A0A5N6KLT8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_004146</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLT8"/>
    <dbReference type="OrthoDB" id="205662at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061863">
        <property type="term" value="F:microtubule plus end polymerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030951">
        <property type="term" value="P:establishment or maintenance of microtubule cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007051">
        <property type="term" value="P:spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045110">
        <property type="entry name" value="XMAP215"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048491">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12609">
        <property type="entry name" value="MICROTUBULE ASSOCIATED PROTEIN XMAP215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21041">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="43"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="231"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8304804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="361" mass="40109" checksum="C97B282216459FEF" modified="2020-04-22" version="1">MTNRIVQQLIIIDNIHQNQPKLKLTKRLATGKLPNTPPKVTIAKMAEQEEDFSSLPLPDRFQHKIWKVRKAAYEDAAKQFEITPDEHDPVFKPFLNDPGLWKGAVADSNVAAQQDGIAALCAFLKFGGPAPVIEELLPALSHKQPKIVAATVAALTAIYHNYGCKTVDPKPVLKVLPKPFGHADKNVRAEATNLAIEFYRWLREAMKPMFWGDLKPTQQTDMEAQFEKIKGEPAPKQERFLRSQQAAMSRAPPPGEGGAEEEDELEAEGVEIDAFDLAEPQDVLSKVPANFHEQLASSKWKERKEALEALYTCLNVPRIKDADFGLIVHGLAKCMKDANIAVVTQAAQCVEVLAQALLWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM01</accession>
    <name>A0A5N6KM01_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM01"/>
    <dbReference type="OrthoDB" id="58297at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47562">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47562:SF2">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="2">
        <location>
            <begin position="180"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="334" mass="37056" checksum="0FC02D95F478D9E2" modified="2020-04-22" version="1">MWESEKLVEVTATRYGKGKGKGNLNWQVASTFSSGIYELNLVACLIFPIVAPPNTCDTISIHITSSTKVKLYIQQSATHSHSRSHSHSHHHSSTIHQLPNMLIQETHKDVITKAGGKEGSMRIFLFHPTIPNYPQARFPGVVLFSEIYQVTGPVARSQRPSKPMTKTRPSQLTPFFPSPPAMANGRIGTTGMCLGGHLAYRCALDPRISAAVTYFATDLHSATLGLGKNDDSLARASEIKGELAMIHGCKDNHVPPEGRDLIRKTLREKGITFSWYEVAWAQHDAFIRDELSKGRYDPAISKICFEILLELFGRTLKLDLGPHDGKEQKIEDIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM09</accession>
    <name>A0A5N6KM09_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_004203</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the membrane-bound acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM09"/>
    <dbReference type="OrthoDB" id="420606at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051085">
        <property type="entry name" value="MB_O-acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13285">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13285:SF18">
        <property type="entry name" value="PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE RASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="504"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="526"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="557"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="598"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8304870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="634" mass="73435" checksum="95F4ACDA14B10C23" modified="2020-04-22" version="1">MSIFSYIRSIYALDTIDTRFTNSSSTPYQVDPTIGRSKRDDSKPGEGVRTDSNGKPVAQPSRWNTPEFYFYYFIFLTVVPYMFWIAYDVSRPSDPNYHKYQHLLSDGWVPGRKIDISDAQYYNFRSNVPYLAILVIFHPILRRIYESIRPIPARVGSPKPNLNKTYISVAEGNAKLQQRAGFDFIFAFVYLSALHGFSVFKIILILYTNYGLATRLPRKFIPAATWIFNIGILFANELSDGYRFTSIAQYISPKGEAGLQNGALLHSWAEWMDNYSGIVPRWEILFNLTVLRLISFNLDYYWSLEKGAGSALEKQLDPANLSERDRVSIPAPDKDYNYRNYFAYAVYAPLYLAGPIFTFNDYISQSKYRPASIDNRRTFKYGIRFLLCLLAIELLLHFDYCVAISKANPNWSDYTPAQLSLLSYFNLHVLWLKLLLPWRFFRLWSLIDGIDPPENMLRCLSDNPSTVQFWRSWHRSYNRWIVRYIYVPMGGSSSRNWKAQVRSIINYLAVFTFVALWHDISLNLLVWGWLIVFFMLPEVIAGMLFPRKKWLNDLTYYRVICGIGAVANLMFMMIANLVGFAVGIDGLKSIISGIFKDFSGIVFLITAWGALFVGCQVMFEVRESEHRKGIFLRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM13</accession>
    <name>A0A5N6KM13_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM13"/>
    <dbReference type="OrthoDB" id="64281at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="150" mass="15407" checksum="D9EC3D0D1EFA3D66" modified="2020-04-22" version="1">MLNPFVVDPTATQKPFSLRVTTDLFASPTKNAFDGSSTAHVQPTTASSITQQKSTTIQDASTTQQAPNSTPSTAQQGFGFITVTVYVTQSSGVMGPTGSSQSTKTGVGAPSSVASLGGSFPSGVAPTSGFPLSIAPFMKRSVQIRGRNMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM38</accession>
    <name>A0A5N6KM38_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM38"/>
    <dbReference type="OrthoDB" id="5421421at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="366"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="487"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="517" mass="57634" checksum="E01F7598741C49FB" modified="2020-04-22" version="1">MLDIYSASIQPPTSLEDSIPITSSTIFKKPPLLRLKMTTMGEPAFGGGHSVPHSAGHSSARTPDVPWTPYSAVSSFNLPAHYDSSLITPITMAPSPHISSRSAPTVRDRDVKLSPAIESPDYPLFGGDADDFGSRLSAAPMKQKLSRSHPAKTPTSEPNYPASPALFCPSPYYGAFGVSATPKSGRSAELTSPNMNTSPQNTASSTIGTDLHRSRHPTPSQSPGNYRVNNPAPILIAPNPNTMRPATRPEEMPYRDGVPYGRHDSMHSMHSISTSIDSYSSTPQQQYPVQKLGPLPSRRKRKTPPVQLDRNLVYSGEVNQEEQILMDLAQMDGVPWKDIAKQFNAATGKSMKVPALQMRKKRLCERLRVWTDCEERALTLACEDYDKAKWEEIAKGMLNHGVQEKWSKEAVQRKFNELFHSDDRSYESEYAASRHAEQIHFDVKMEPRTPWPSHGDRDGALRNLTDDEVTLVGELRSRTASDASSVHFQQQHQHQQIIYAQQHHQHHQNHQEAWVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM50</accession>
    <name>A0A5N6KM50_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL20 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_004239</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM50"/>
    <dbReference type="OrthoDB" id="1294322at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00273">
        <property type="entry name" value="Ribosomal_eL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028877">
        <property type="entry name" value="Ribosomal_eL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023573">
        <property type="entry name" value="Ribosomal_eL20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021138">
        <property type="entry name" value="Ribosomal_eL20_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10052">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01775">
        <property type="entry name" value="Ribosomal_L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002190">
        <property type="entry name" value="Ribosomal_L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160374">
        <property type="entry name" value="RplX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL20" evidence="4">
        <location>
            <begin position="4"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8304914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="130" mass="15690" checksum="D5714BE1D38F634F" modified="2020-04-22" version="1">MGRLREYQVIGRHLPSEANPAPKLYRMRIFAPNTVVAKSRFWYFLMKLRKVKKANGEIVSLNEISEKRPQKVKNFGIWIRYDSRSGTHNMYKEYREMSRTDAVEALYQDMAARHRSRFRSIHVNREDRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM51</accession>
    <name>A0A5N6KM51_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_004068</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM51"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF461">
        <property type="entry name" value="AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="15"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8304707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="413" mass="45210" checksum="64C9C402219AF032" modified="2020-04-22" version="1">MYNIFLALDSDKYPAKSYGDLFFRVFGTWARHGINVAQSIQLLFTVSILILSNGQSISQISKGSLCFVVCLVVFMAAGMVLGQIRTLQRFGWLANFAVWINILIIFICMGVVANSAPNYAAVEASFGDAFGPGPVHRYAGTPPSGKASGGEGFVGSLNGLNQAVYSYGGAMLFVAFMAEMRHPMDFWKGLICADLFIYFVYMFFGIFVYSYQGQFSYNPVIQGLSPYNWQTAANIMNLITGLIAAVLYGNIGIKVAYVDVFQGILKAPPLTSKPGKMLWIAMVPFYWAVAFVVCAAIPQFSYISGLVGALCILQFTYTFPAILGFGYQIQKDAMLPGEESFNPQTGTYNYIDRGVKRWIRGFKVNWLFNIFNFLYFLGALTTAALGIYSSCLGLISAFDGTSAATSFGCTPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM53</accession>
    <name>A0A5N6KM53_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein transport protein Sec61 subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_004244</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC61-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM53"/>
    <dbReference type="OrthoDB" id="5401193at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005784">
        <property type="term" value="C:Sec61 translocon complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030671">
        <property type="entry name" value="Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016482">
        <property type="entry name" value="SecG/Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13509">
        <property type="entry name" value="SEC61 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03911">
        <property type="entry name" value="Sec61_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8304920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="15984" checksum="1B951AF68B8AC823" modified="2020-04-22" version="1">MSSPRSASPANSPSAAASGRPSSPTPPGGPKTAIRRRAAADQKDKVANARPSSTRAAGAGGSSSTMLRLYTDESPGLKVDPVVVLVLSLVFIFSVVALHSHSQVLFLNLVLQCWSRGYKGAIDVLLQGEASKWCLGILQLGKVKGSIYGALLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM63</accession>
    <name>A0A5N6KM63_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM63"/>
    <dbReference type="OrthoDB" id="5539371at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="88" mass="9414" checksum="52E137EB11ECFA1B" modified="2020-04-22" version="1">MVKPLSFKGDKKTKKRKRVDTAEKFGDSETSASQAIAKPQEEEEAAPDDDTWVTAEAAGDVVGPVVFVLPSDIPSCIACDTNGKNLTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KNW3</accession>
    <name>A0A5N6KNW3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KNW3"/>
    <dbReference type="OrthoDB" id="3700495at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8304799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="74" mass="8820" checksum="04470EF4EAE74BA4" modified="2020-04-22" version="1">MCDYTQVEFRCGHVRYTVRAWCTNYETTHRRCPPNVVAVEFRLGESEMCGDCKHVVEMPEWYSKITKKHARIHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KPV9</accession>
    <name>A0A5N6KPV9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KPV9"/>
    <dbReference type="OrthoDB" id="5327145at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8305149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="353" mass="39403" checksum="5A8A2C96AA7715CC" modified="2020-04-22" version="1">MKTTNAKTKVFQTPAGTAPEKELEKTVSKQTSARRPKHKVSEKVKIDVHGDESPLRDIEVEYMPPRPKDLPYDSDVFPTGCLNYDMLKPENLTKGALSDYYNTNDKSGKSKLERDLEKSSVERAKKTDEQILASMEEDWTVGDVPETFRNPKKRAPAQQAKTMVLKEQKTRTAIQSRGPATVASRRAVSALSNHPKSGAEPFKRPSTAIPRPASTFLTRRKTPTFAPVTNNTMRATAAAANSRSTIGYTKGRSASYGLQKKDVPSFSLKKKESATLPRSISNISHDSDSTITPARFAQKENLRETEYKKLDFLRAFDVHDEELEPALKCGLPECLIKFDEDEEEFVMTIGGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JMQ5</accession>
    <name>A0A5N6JMQ5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyltransferase family 31 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_010564</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000021">
        <property type="protein sequence ID" value="KAB8289651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JMQ5"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10811">
        <property type="entry name" value="FRINGE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8289651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="32914" checksum="41EA739EC47C6272" modified="2020-04-22" version="1">MKSKRPFLLAVSLIIVTAIILVARHGSFGAVPYFVYQEVGADYGWVEEDWIENAAEIESAQNCHAAESFEWLEKYNLSYPLKVAHRDIIAMPNHGARPSITTIDEPLFDNQKVFQRGGLSVHSFVDHCSPLTLEVPYPPVTEVDASHMIFGLQTTMKRLRETKQHLARWLPNTGARLFAIVKESEEELASKSDMARLQKEYRKAGMQITIIPPVKKEDFFNQRYFSLINVMYAARNKKTQWTVIMDDDTFFPSFRALIDELALHDHTKPQYIGGLSLSFDATGQNYPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JN01</accession>
    <name>A0A5N6JN01_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_010450</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000020">
        <property type="protein sequence ID" value="KAB8289817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JN01"/>
    <dbReference type="OrthoDB" id="2017782at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052645">
        <property type="entry name" value="Pumilio_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47093">
        <property type="entry name" value="PROTEIN JSN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47093:SF1">
        <property type="entry name" value="PROTEIN JSN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="451"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="PUM-HD" evidence="7">
        <location>
            <begin position="599"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="4">
        <location>
            <begin position="660"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="4">
        <location>
            <begin position="696"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="4">
        <location>
            <begin position="733"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="97"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="524"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="916"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="931"/>
            <end position="950"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8289817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1126" mass="122515" checksum="CC30DDAAEAF163E5" modified="2020-04-22" version="1">MSNKRSEHLNLGHLPQPAVGFPRSGSSTTNTSPTEASIGGASLRSPFGIPSLNSTGKMASNTRSGAGSPSHELGTGSSVSNVNRIYAKRAREIQAQEGFVNSNPWGPPTSGNSTPLRETILESPTDGFPDFAQLPTTETTPARRARAGTVPSRFPPGGISNPVPNLASLAKTSRPTPSQSPFKSPSPNLGDMSDPSTSTGLLNRLRSGSTPQNSQYRSSPFGHSLFTSSWGLPSGRDRTSTLQSIASQSSNGPSSPAQSSFSREGNNDNEIRTLDYLGLAETPQPPRAQLVNPLIANFVDANRQSNRFRSYSVNAKEKYAEDEEDDEFGSGSMTPYEHQQAQLQMQMAATNAAIQQHNLAVQQVQQYASQASASRPRARTAGVLDSPNTSRLLRDYYPSASRLGNAITASELREAEEFAGLPEAVAAMSLGRSNSGNDHLSPNDNLEGPTSALWLGSIPSSTTTSTLTEMFKSHGPVQSARVLTHKNCGFVNFERIESAISAKAMMHGKEIFPGAGPVRINFAKPVSPATTPGPDGAFPSPSPDPFSKGLDSTANAVDANGVPGVISRPGTTEPPSPRLRDIKNDILNIVSEFGATADDKIKIGQSLQSSISYDKWQSEIPAIPEPSHNRVHDAPKLRDIRKRIDNQSWSPAEIEAIAMEMLEEVAELSSDYLGNTVVQKLFEHCSDDTRDLMLERIAPHMAEIGVHKNGTWAAQKIIDVCKTPKQMTLIVQNLAPYTVPLFLDQYGNYVLQCCLKFGSPFNDFIFEAMLSKMKPISEGRYGARAMRACLESHHSTKDQQRMLAAAIALHSVQLATNANGALLLTWFLDTFINQKLESDARDQIFQALFFSQDDETLEAILSDQACGATLIFKVLTTPFFDESIRSKVVENVRNVLLRLKAQPAQGYKRLMDEVGLSTRNGSAGPSREHSQQQLTDRPRPGSQQSQANGQHIPQSQYGANQYYPQMQQNPQMQQNAYDMGIGMQRTDSMDSNVTPYQQYALPSSMFPQSTPMMQPMNMQQLQYQNMARGTPPLNNFYPTMQSGFGGFANPQMADQYRGMQNASPIQPPSQQMSPSPMAGQSSFGPPGFNNMGMGMGGYGYNGLPVSGMQNVSYMQQEQVNNRRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JP05</accession>
    <name>A0A5N6JP05_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_011114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000018">
        <property type="protein sequence ID" value="KAB8290247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JP05"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8290247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="152" mass="16982" checksum="AD5F29F324C74045" modified="2020-04-22" version="1">MCSDKVDIDQGTYSASLAIGPVRDFGGNDIYRSFARKGWFPSHRCRSFRSGAISPGAHCGLQPLYEVALGEFDIKYSTILFGKFVHIVHQCEICEGLLTCNGLEPFRTFSGPKCGPFPFESCHEYSSQYRRLIPRFLAKKEATVNQTGEEKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JQT9</accession>
    <name>A0A5N6JQT9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_010487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000020">
        <property type="protein sequence ID" value="KAB8289855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JQT9"/>
    <dbReference type="OrthoDB" id="20109at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000171">
        <property type="term" value="F:ribonuclease MRP activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034965">
        <property type="term" value="P:intronic box C/D snoRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013241">
        <property type="entry name" value="RNase_P_Pop3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28272">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28272:SF1">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08228">
        <property type="entry name" value="RNase_P_pop3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8289855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="240" mass="26602" checksum="15CC7147CDB080CF" modified="2020-04-22" version="1">MDNQRSKTIYQLDTPFTAVQWPEISSKHQETVLELLCSILSPIGTHRSNHITPSKGKRSKKRKRRAAKTGEEKSSETPPPPEMSPYIITGLNSIHRTLERSIKKAPENSQALDIPTPQTPHFSTIFFSRSTTPPILTSHLPQLIATASKAHPSKPLTKIVPLPQGSETRIAAALHLPRVSFLGILDDAPNSKALLDVIRDCVGTIEIPWLDEVKRGEYLEARIRVIQTTIGNSKSSEKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JQZ1</accession>
    <name>A0A5N6JQZ1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_009884</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JQZ1"/>
    <dbReference type="OrthoDB" id="5598844at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013933">
        <property type="entry name" value="CRC_Rsc7/Swp82"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597:SF5">
        <property type="entry name" value="LOCALIZATION PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G10600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08624">
        <property type="entry name" value="CRC_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="446"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="487"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="520"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="547"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="569"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="591"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="618"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="635"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="651"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8291197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="662" mass="73160" checksum="ABF197780F76BFA0" modified="2020-04-22" version="1">MYTAVTNGLGGGVSEGPFHPTTINPQALNQGSLNPSPRIPPNESPRGIKRSRSPDTYSEIPQVGNLADDGDSKPRKRGRPMKAKVSVNTSENSQQHQTQTPNSTSIQGDQPQTPQSQHTVLPLNRTPVMHATQTATPKPTPKQGMKALPTVRDHTTDQLSTEGDEYIPREYDDQGEKKVTANGHLNDGREYRCRTFYVPNRGDKLFMLATECARVLGYRDSYLLFNKNRSLYKIIATQAEKEDLIHQEILPFSYRSRQIAIVTAKSMFRQFGSRVIVNGRRVRDDYWETKARKQGFTEDDLAGEKRPGAAKARDAAAAAAEASAALAVTPHHPDLYSNGPGHYAYPQHTVSSGMMGIPGSTNPLPMITTLAPEQTDMRLRDYSNIQRPRQELTGTAYQDRTQPSSGTDLSNHVNQAAEYSKQINQQRSRSHDYLERRWRQPHEVVGGNMVQPVVTHDGIPSTQALRSPQASQSIAQQPILAHQGPQHIAYSQPSHQPGVVSQPPIRSISSRQDQIPGRSPNISIASTSNMNQGTNPYQFTSQNHMWPSSQPQQSPQQHAFNPSYPPHPSQQSPHIQQSPHQPPPPQIRQSGSNPQIQPSLQYPSMQGMGQNYPAPRNVYQSDSSNQQFMQPATSGPQPGAQGWAPQQPAATSASWGWTGQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JQZ6</accession>
    <name>A0A5N6JQZ6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_010907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000017">
        <property type="protein sequence ID" value="KAB8290476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JQZ6"/>
    <dbReference type="OrthoDB" id="3534908at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8290476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="114" mass="12260" checksum="DD073DD35F3B45F2" modified="2020-04-22" version="1">MVAVTGIVTAGASALGLAAALTSMHLPAKTYRVERRRRLSQPADQEQSEMARLALQKTNSAGSITEKTKSSFQPGKKLLGKVKEKGQGRKGRERKGKEIGLDIDLGMGMEFSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSX3</accession>
    <name>A0A5N6JSX3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_008354</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000016">
        <property type="protein sequence ID" value="KAB8290715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSX3"/>
    <dbReference type="OrthoDB" id="417877at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="11"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8290715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="392" mass="42373" checksum="317AF7485EFBEE88" modified="2020-04-22" version="1">MGTLTPERKIRIAIIGGGLAGATLLRSLLTHPHLSADIYESASAFSERGAAVGLAINAQNALAEMGIADVVQKAGGVRMHSSRTIVVSWGRGPHAGELIFDLASELQGWVVHRAELLRELLGPVPRESMHTNKKVVGIEERDGGIAVSFQDGTVVEADAVIGADGIHGFVRGHVLGEEHPAVKARFAGFWDCRSLVSMQRAKEVLGEKYFEEQRQYVWCGDRGFFLHDVLDGGETVQCIASVMKSPTSPWETDEKTRKKDLHRTTLEAAFEPWTNSPISEPMIELLLENPDLQAYAQWHHSENAPTYTKRAVCTMGDAAHAMTPWQGSGAGQAIEDSLILSTLLARITRASQLPSAFAAYDAICRPRSQRVVASSVVTGKLMCGGGAERVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JT82</accession>
    <name>A0A5N6JT82_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA repair protein RAD51 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_010032</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Required both for recombination and for the repair of DNA damage caused by X-rays.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the RecA family. RAD51 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RecA-like protein family. RadB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JT82"/>
    <dbReference type="OrthoDB" id="10251254at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990426">
        <property type="term" value="P:mitotic recombination-dependent replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19513">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000092">
        <property type="entry name" value="DNA repair protein Rad51 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011941">
        <property type="entry name" value="DNA_recomb/repair_Rad51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011939">
        <property type="entry name" value="DNA_repair_and_recomb_RadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02239">
        <property type="entry name" value="recomb_RAD51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF39">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003336">
        <property type="entry name" value="RadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="10">
        <location>
            <begin position="15"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="11">
        <location>
            <begin position="195"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8291350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="264" mass="28822" checksum="D62F1571E65E9406" modified="2020-04-22" version="1">MGFTTATEMHQRRSELISITTGSKQLDTLLAGGVETGSVTEIFGEFRTGKSQICHTLAVTCQLPFDMGGGEGKCLYIDTEGTFRPVRLLAVANRYGLSGEEVLDNVAYARAYNSDHQLQLLNQAAQMMCETRFSLLIVDSATALYRTDFTGRGELSSRQMHLAKFMRMLQRLADEFGIAVVITNQVVAQVDGGPSAMFNPDPKKPIGGNIIAHASTTRLSLKKGRGETRICKIYDSPCLPESDCLFAINEDGIGDPSPKDLEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JTC4</accession>
    <name>A0A5N6JTC4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Short-chain dehydrogenase/reductase ABA4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Abscisic acid biosynthesis cluster protein 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Short-chain dehydrogenase/reductase aba4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_008074</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Hormone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JTC4"/>
    <dbReference type="OrthoDB" id="294295at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009688">
        <property type="term" value="P:abscisic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005559">
        <property type="entry name" value="PRK07231.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639:SF1">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00068707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00069153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00074993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8292332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="261" mass="28192" checksum="C425D0E5219D7DFF" modified="2020-04-22" version="1">MSSTSELKVLGSRLKNKVAIVTGGGSGFGEGIARRFAEEGCKVIIADIDSVGGMRVASVRPHSMLFVKMDVTSEEDWERMLETTLAKWGRVDICVNNAGTSYKSKPTLDVIEDEFDRVFNVNVKSIFYATRHFIPNVINQGEGGSMINIASIGATRPRPGLVWYNASKGAVNNATKGLAAEYGSKNIRINSICPLLAATGLFSTLTGMDDTPENRDKFLFNVPLGRICTAEDVANYCLFLASDESKFVTGTCLEVDGGRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXA4</accession>
    <name>A0A5N6JXA4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_009276</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2289094at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870">
        <property type="entry name" value="PROTEIN TAG-278-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870:SF9">
        <property type="entry name" value="PROTEIN TAG-278-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="386"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="945"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1005"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1071"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1513"/>
            <end position="1543"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="636"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="817"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1199"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1328"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1547"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="285"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="952"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1008"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1071"/>
            <end position="1088"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8293791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1580" mass="168999" checksum="E4560C5A67B7DB46" modified="2020-04-22" version="1">MADVESPVIPQATSKPEETSTDILEDTPVTPVEANAEGTADAVPEETTGTASEVDTETEKESVKSTDADKTPTGATSGVKKENALPKRAGSSAAPRRPISGSATRPTASSGVKPAASSTTKTTGGLSKPPTRPPTGSVVRKPTSSATGPTSSSASHRAPSAAGSHADEKKPATPAARRVSLAPSHTNTSKTPGTAAEARARPVSMHATTTTTTARKPVPSAAPAGQTSPKTAKTTSTTATKPASTSSTTATLSEARKRLNALQGGGAPHPAPKPSSLGSTRSVNSTSSATAAATAAASTKEVEELKTKLTESESKVEELKKEITISQEKLLEVSKAAEEESKRISDAEESIRATHSELVEKLNADHKAILESLQAQLVEAESAKSAAQEASLAAIEEAKEAASSRGATEHAEALEKLKAEHSAALEALNAELAAARETSATEHANALEAVNAELAAAKEANAAAIAAAAEKEAEITDLKVQLEKAIAECAAATESLKSLQAEHDEKIKTLESDFESKASKHADTLEELKRTLTEEHNAAVEALKSAHSEELAKGTTDASSTYEAQISELTTKHEENLTAIQKQLESQAGEHAKALEELKNTLTEEHTVALEALKSAHSEELAKGNTDVSSTYETQIAELTNKHEESLAAIQKQLDEVLEAQKSLEAAHAEKVYNLEGEVNSLREILEKDTIALATSEKEISEAKEDAEAAERELASAQEQVAELTAKLDGLQSTGTESESALEAAKEELEKSKEEVVSLQKALEQLASEGKDKDEVHNKIKEELATTVQSLDQKTKEISELLEKHSLETSALNEKHLKELETISNDYQKEIDALSGDSGIRDEFNALKTKHEELNKNYTEILAAHEHELEKAKQCHAAAIVELDNNDKAHQRALEELKTNHAKALDEAHDRAISASHSSHSSELQQLEHSHAAAIAELKSEYEKSHAKALGEAHSQATSAAQQAHEQELEKLALSHAEDLATLKAQHATIQANHEEAVAALKAEHEANLTSASSDAESQKNAQQAHQQELEQLTRDHAEDIAALKAQHATAQSTHEEAIAALKAEYEANLANASSDAESQKSAQQAHQQELERLTRDHAEDIAALKAQHATAQSTHEEAIAALKAEYEANLANASSDVESQKSAQQAHQQELERLTQEHAEDIAALKAQHATAQSTHEEAIAALKTEHEASLAIASANLENQKGAQQAHEEELERLMQSHAQDIASLKAQHMTVQSTHENAIAALKAEHEAKLATASANIESQKGTQHAHEEELERLMQSHAEDIASLKAQYATVQSTHDEAIATLKAEHEASNASASSIFQRQKAVEAELQNEITKSKQSLNSVQDELEALKQDLAAEKIAKANAEADLEAARNVKLDTSELDALRRELQALKNQHEAALSSAQQETARATQELTASKLQLESANAELEKEKATLEQKVKTSKDDYKTMHESMTELLEETSKDCETLDARLKEAEAQLKVKDAELAEAKTKLSTTSPPKTPTFGGLFSRGFAETDGKDSDGTGESTDVVATPESEHDNSSAALASLAKARVTVEQLEKMNEDLKKDNMRINFRRLWASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXA6</accession>
    <name>A0A5N6JXA6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXA6"/>
    <dbReference type="OrthoDB" id="4772806at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="210" mass="23563" checksum="AEEE6FD604BA3465" modified="2020-04-22" version="1">MVSLTPFIFSSPSFSCSISSSKRSAHSRTKFRLSSHITGRSSYATYRAENASREQLLDPLDHSLIEPTQIYNQEPRRLTLGKFEDYYLLEATSRPVLSTEIQPRDSKKNSARMASNFRPDANGNTNSIFGESFETTTATLRNERRRSYGIGGAGNIRKPSEVIYTPRERRRSSVFSNPSVSVYLILLVQRGEASCHGLELEVSKGKRNSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXE6</accession>
    <name>A0A5N6JXE6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_009306</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPL family. K-HECT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="423283at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045322">
        <property type="entry name" value="HECTD1/TRIP12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057948">
        <property type="entry name" value="TPR_TRIP12_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25579">
        <property type="entry name" value="TPR_TRIP12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="8">
        <location>
            <begin position="1536"/>
            <end position="1891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="745"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1100"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1225"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1333"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="7"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="134"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="754"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="786"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="818"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1100"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1155"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1238"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1249"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1342"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="1858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8293824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1891" mass="205753" checksum="B91E0487224FDE19" modified="2020-04-22" version="1">MAKEISRPLSTATSISSSSSFAPRITRSSTRQAANSSETTAGSSATAASAAAAPPGRPSAPSRKRKATVRESSPALEPESTKATPSKRPKRQKVSEPEAPTPASATSSRRKNAKAPAVMSSHRKVKIDGVYGLVSNNIYSDSAGPSNEPSNTTATSSRRKSNRNSKKGGQDASTNTPSSGKKSKKSTAADKDGDTTMNDADEKPPPHPLHDDDSDENDDDEIPRDYDGGDDDDDDPFGSFGGPGGPPHGLSSTLRALSGMMSGVSSRLRDILTQLKQKDDPSIQLIALQELSEILLVSTEDNLSGHFSPDAFVKELVVLMQPSDFGFGEGNPEMMLLACRCIANLMEALPASTANIVYGGVVPVLCQMILNFGFVDLAEQALSTLEKISVEYPASIVREGGLTGCLMNLGFHDTNAQRTAVTTAANCCRNIPEDSFDVVKDVMPNLLEVFSSNDQKVVEQGSLCVTRIVESFRYHPSKLEELVSTDLLRAILRLLLPGSTNLIGANIHTQFLRVLAFTAKASPNLSAELFKMNVVETLYQILTGVSPPSATEDAASKLDSVVIMQALIHRPREQVIETLNVICELLPGIPRGGSSIIDDDTDVEVASGSPNVSSGSRKKSANEIRIELLEGCKEEVKRFAIILFPTLTDAFSSTVNLQVRQKVLNAQLRMLSNLDKDILMDALRSVPYASFLAAILSQQDHPSLVVLALQATELLLVRLEDVYRYQFYREGVIAEITKLATLEETQTENKPPVNESTSATTQVGTNRKISEKAAQNGEARDADNSSSDEDNEDNENHEDDNENEVAQNDDIPEDVTASPVSSRGSTVSLDGPHRHASSDLKSMMNIIAARAQKFLDVHETEKNSKAMKKKATQILTSLQSLASDIRSFYLHQGQGNGVELFTKLASYFDGDVLQSVTSAELLNSEIVQVLLEVFNNPNEQLANDARSAFLEVFMGHTLAKKSNSGADSPATPFGLLIHKLQDLLSRSEHFEVVTVHSNSFDGNRSSAASMLAKQIRLKLVADEDSEIPRSYRNIMVSIHAIATFKALDDYLRPRISLSDRPRPPRARDGLSGALAALAAAGLPNPYAGIPNAQARLAAAAAATNPNASTPRTSRRAKSKSGPVPTPASADQSTSHTPAEKPARRSSRRQQAQTDPNPPPPPPPPPPMQEEDALASALECADERQMSEDDDLEDSAALDTIVGDLEEDMEEDSPVDPTAVNLEVAAGGKVTARKEDGTRVSTPSQSVPNTSRSSSALQAAQAALSTPTTSRPMSYAAAIQSVPSDWHIEFSLGDKVISNETTIYRAVHTMANPAEEHSNRSVWSAIHPIKFRRVPGPPPPEPSSLSQASEVSTETTASGIPASLDKHPATSSILRLLNTLHALNANLDDVLADNKDTLKLNAEPLSQFVNTKLTAKLNRQLEEPLVVASNCLPTWSEDLARLYPFLFPFETRHLFLQSTSFGYARSMTRWQNAQSADESRRDRHRDERPFLGRLQRQKVRISRSKILESALKVMELYGASQSILEVEYFEEVGTGLGPTLEFYSTVSKEFSKKKLKLWRETDANDTDEYAFGARGLFPAPMSEEQSLNENGKRILHLFKMLGKFVSRSMIDSRIIDVSFNPTFFRIGDASNPVTPSLGAVKTVDPQLAKSLKMIKKFSIAKKAIAEDSTLTATQKVLATEALEIDGAKIEDLSLDFTLPGYAIDLLPNGSNIPVTIENVDLYLEKVIDMTLGSGVQRQVDAFRAGFTQVFPYSALKAFTPDELVMLFGRIEEDWSLETLMDSIKADHGFHMDSKSVKNLLQTMSELSLPERRDFLQFTTGSPKLPIGGFKSLTPMFTVVCKPSEPPYSSDDYLPSVMTCVNYLKLPDYTDLDVMRRRMNTAIKEGQGAFHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXF1</accession>
    <name>A0A5N6JXF1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_007799</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXF1"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045072">
        <property type="entry name" value="MKRN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224:SF10">
        <property type="entry name" value="IP09428P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224">
        <property type="entry name" value="MAKORIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="361"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="444"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="375"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="391"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="456"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="479"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="507"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="572"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8293490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="614" mass="65086" checksum="ABCBD76F24A86378" modified="2020-04-22" version="1">MDTILGNGAPQPQQPPHIRNGSSSNNQFPRHMSTNSLNIPNGQSGPINGATTRGDGVARSPPTRQNTGHVPCKFFRQGTCQAGQACPFSHDPASTTDNICKYFSKGNCKFGPKCANVHVLPDGRRINYNKNMPPLAPGHLNLGGRINPDPYHGQGSALTSSFARAQGIPPSPYGQPYGPFTTQEDGLVPIIGRQSVDINIPTIDTSYASHAGSNYGSPRDDLMDRFGLGLSPVAAKGLSVMDVPLPASFDSNGVSWIARHGPVASSVPTKFGIDSPPSSVGAAKPSDALRNLHSSAFGDDTRDRFNGTASSPPSEYYGKRTMHSHRMAKPKIMSASLPQEQDWSEAFTFEEDLLPESLNDLMTPAEKARRGSRAAYDESKPSRGFYDEVRSTYSGAGTPINDTPTKFGSPSNASPSRWGPYFQQKHKEEDEKISRASAFGHVGSPLRNSLLHEGASPSSRSIARPNTSGDASPYLASPPRQTSMSIISQQLQRTRLARAESNGSEPSLLSSSAARTTTTPIGSGRSAFSADRQASSSSIGGSGRFTTPIDEEQGDFVFNMEGMDDDEKSQKKSSGGWNIGGSSKSPSSGAVGGGRNISANKTNGSGLDGMFGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXG3</accession>
    <name>A0A5N6JXG3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXG3"/>
    <dbReference type="OrthoDB" id="529205at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="147" mass="16595" checksum="FD76FD930F38F10B" modified="2020-04-22" version="1">MDEASVELRSIGDSINIKKTLSNLPLTSKTSPHNTQTSKMSFIIRQSIRAARPVSIAVPARRTFANTSMRCLKESDRHNPEQAAANERHKQDQLAKQKEGKNHWKPELASDSEEAVVADRHEHSDHSEKGIKELQKKTEGHAEEKHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZH8</accession>
    <name>A0A5N6JZH8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thioredoxin peroxidase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Thioredoxin-dependent peroxiredoxin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_006895</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8294941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZH8"/>
    <dbReference type="OrthoDB" id="195498at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000020">
        <property type="entry name" value="Peroxiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF16">
        <property type="entry name" value="PEROXIREDOXIN-5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="10">
        <location>
            <begin position="6"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="8">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00079296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR637944-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8294941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="210" mass="23370" checksum="DF7543558375C6DD" modified="2020-04-22" version="1">MSEATLTVGSTLPENVKFGWIPPTPENEDIKACGIPITYNASKEWANKKVVIFSLPGAFTPTCSASHLPGYIAKLPALREKGVDVVATIAYNDPFVMSAWGKANGIHNEDILFLSDSDLSFSKLFGWTAGERTGRYALIIDNGKIVYAEIEPGREVTVSGADAVLSKLHIYVMVWVWTKIDIVYELREGKENISFCVFQISWKFTKWKIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZJ4</accession>
    <name>A0A5N6JZJ4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006894</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8294940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZJ4"/>
    <dbReference type="OrthoDB" id="10250268at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8294940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="73" mass="8735" checksum="411CF71550C5FC28" modified="2020-04-22" version="1">MLMQSQYRPIGQRDRRQSYSIESAEARRHCKYPADEMKIELLACYNKHYVMSLWTLMGRLFHFGVIIIIGKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZK5</accession>
    <name>A0A5N6JZK5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">KOW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_006926</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic ribosomal protein eL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8294974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZK5"/>
    <dbReference type="OrthoDB" id="1875589at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23702">
        <property type="entry name" value="eL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000030">
        <property type="entry name" value="60S ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039660">
        <property type="entry name" value="Ribosomal_eL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002784">
        <property type="entry name" value="Ribosomal_eL14_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11127">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11127:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01929">
        <property type="entry name" value="Ribosomal_L14e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="7">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8294974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="145" mass="15902" checksum="4C72EC64CF81756F" modified="2020-04-22" version="1">MGDADIKASSWRLVEVGRVVLVTGGPHDGKLAAIVEIIDHKRALIDGPATDKLAAVPRQAISLANVVLTPLVLKGLPRAARTGVVQKEWEKAGIEKLWQQSPWAQKREKQAKRAALTDFERFKVLRLRKRAGFQVKVARAKIAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0P3</accession>
    <name>A0A5N6K0P3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0P3"/>
    <dbReference type="OrthoDB" id="5389296at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="330" mass="35943" checksum="26E59B54FAA5A15B" modified="2020-04-22" version="1">MPPPVTPSPHRFVIKKQPPPPRSQLAQDSTPRPAGTQQFNTTPRFTFSSTPRAAGSQTIPSSTPAERYLTPARKIPKVRENIELSTQELEDDYAVDTRLSKRQRTSPLLAADAVSEENDDLLSSSLSIVSSPISHRPNHIPTTNIKPKFLLSTPLPPSTPQSTAPTTFLKPPRFRPPDPTETQGNADPLPEQFSPHRKGQKYVVGGLAAEVRDWLINIDSAVPSHGAPGVQKGKDRDREWLVKMVVDEVSGGGRMGMCLVRGRKMRDVEGVEMVDDSGVVKVLLAGEGVGTGLQRGKDVEVGRVVGIKGPVWEIAIEGEKWGVGVDWEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0S9</accession>
    <name>A0A5N6K0S9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extensin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8295767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0S9"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018853">
        <property type="entry name" value="DUF2457"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10446">
        <property type="entry name" value="DUF2457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="63170" checksum="A37EF85BD4900265" modified="2020-04-22" version="1">MEQEGSTEKATTTSRLALPDTPPARRRASSRSPSTTRKPRPTPTASVRPHRESTGTIRRASQSPVAIRCKPKYVIAGEKDLQSEAARFHEFCSEGVEEDDWIRVDEEVPKAKITINDTLAKEIRIRRLGSEAEEEALEEDDEDEFEDGNDSDNEDVSDEEQDDEDDETDRVYSDDDETDGNETDNEAGFADSDDEDDTEGDFAFWTPGRLGNATIPIPNAEASTYRASANRTASASSIESLNDAAPIREMSRGKRRSRRPRSIKIRPGTPDLPDSTDFVCGTLDEDRPLEDAYVSCMTARKYAKHIATPQDIDPSFPTSDPEDEEDEADDVAKTIESDEHVWMQGKFEDSDSERRRARSRRSPGHSPRRLHSPPPPKQRLRSPPPKQRLRSPPPKKRLQSPPPPKKRLQSPPPRKVFGNDSPKRVHSPPPTRTVYSSGSPSASESKPIKFAPLGSRPGLTHTKSLPRTPNAFCRQYTASRIAAANEIAAKDDGDGPLRGAIDIVKGLEQKRQRRKEKFYQKHCANRARKPQPERRPQPGKGAERMRELGLLMAGKTGTNDPYILSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0U7</accession>
    <name>A0A5N6K0U7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ras-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_007190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0U7"/>
    <dbReference type="OrthoDB" id="775356at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05137">
        <property type="entry name" value="RasGAP_CLA2_BUD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039360">
        <property type="entry name" value="Ras_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194:SF60">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN RASKOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="3">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="335"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="362"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="383"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="430"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8295282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="526" mass="58239" checksum="136FD6674D4E2B04" modified="2020-04-22" version="1">MDREQSVRDMGKSLNTEANLLFRGNSLLTQALDFHMRRVGKEYLSEILGEQIRTINNINPDCEVDPSRIESDGAFDKNWVSLIALTTDVWRSIADSATRCPPELRQIFKYIRAVAEDRYGDFLRTVAYTSVSGFIFLRFFCPAILNPKLFGLLPDHPQQKAQRTFTLIAKSLQALANLSSFGQKESWMEPMNKFLYQHRQGVKDFLDSICAITPERTAFAVPASYSTPITILSRLPPTSREGFPSLPYLIDHARSFADLVKLWLEGTSNSMTQYFEGDLAEFNELCIALKKRTDECILKAEDYGDRVADQVSLQFEDIVDGLQSTNLQESPQIHAIPHPQSYFPPEPEQQHPVLTPPWQDYSMSNSNATSINNTSQIHLRAPGSAGSGSEKTGATSSSSKEKEKKEKQNFWEATFGKDSKYQRPYAPAPSSDNTAQQLGMQASSPPGDKRGLAGFGINRQEKQSRSFLGGLRRKGKHEPKSQGSGSSNDGGFVMVPAILGGQGIGPGMGISLDTSGGMEGGQWEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K153</accession>
    <name>A0A5N6K153_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8295855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K153"/>
    <dbReference type="OrthoDB" id="4174342at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="525"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="612" mass="68187" checksum="42A0F971266E1538" modified="2020-04-22" version="1">MFGFIRWKGKFKDNQPKINSAPHRENKSAVREHSEERKFSLGGSWHVMSSFSVMNTSHSPSESSRAMSPEVVSPAHPDRPIRPLPKRRLRERLSPDVAESIKYPPAPKTQTPLFYYPYTVRDDVTASTLVESSHPGDRPQVDNIDQNYIPRRNGEDPESEDEEVYRAARLYPRQSVDNSGRSYRYVQKPDSKHPNPQPPASTASSADGYDSFENTNNKKKRKIPTPGDSNINGVHLSNDLAGMGISGPDEEDINGAGYYHAGGSASQGLSGPGRGRYGRNRSGRSPLRTLSDASGNWGNGRNSKPRQPQWPTSNDSSGIISTAIANAEKESPITHSRGQENISLLQQQASKKPTPTSTQFTFTCDSQVPAAVPWPGPESTNMHQSPAARSMMTHGTQTSPSMQHSGSQAKQGFPSSQQSAHTQKQNVPQTAPPKRTRRRASREYEIAARQRRQQQEYQNMTHPPNPEDNWICEFCEYERIFGAPPVALIRQYERKDRRIRKQEAERKRLLEKAKTKGRKGKKGSKAAVKGTPQDHQSQHQTSQQGTFADQNQSQGTQSEDYPDDEYEQDYAQGHPISPGAHSSLRPGEVLPNDQGRRLYGSTGRSSDGRIVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2T1</accession>
    <name>A0A5N6K2T1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2T1"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="84" mass="10101" checksum="D2BA6E1F79855441" modified="2020-04-22" version="1">MFDRRLRFYEVYEQTSKRANEQTSKRANEQTKKRESKADERRVEKKIIKRKAKTHAIIPLNPIPSHQITLDRYRNTSNKPNTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2W0</accession>
    <name>A0A5N6K2W0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2W0"/>
    <dbReference type="OrthoDB" id="540004at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="80" mass="9052" checksum="2E02C5A0678D2BCB" modified="2020-04-22" version="1">MAPTVLETEDHSRDAAFNKAMHKDSSNAEGGFRAMMKKDSSAQKAAVDEYFKHWDNKAAKDETKEDRDARVAEYATLTRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2X1</accession>
    <name>A0A5N6K2X1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009142</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2X1"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8296394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="170" mass="19301" checksum="6CFFAA95A0DAB3F3" modified="2020-04-22" version="1">MDRRMYCWQLVTLFLVEHNDLDIHFVSFEKLKRDIETISRFAAQNSKSQQGITFHQLKGPSLAKALNDEGFDVDAAINAPGIRGFGILCRNMELWLMPWTGPEYIDIYREISEILEEVDPVMVAVDPLFGPGLDAVRAQGRNHAVLSPNSLKENFVQLQPRGAALWKYPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2X6</accession>
    <name>A0A5N6K2X6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2X6"/>
    <dbReference type="OrthoDB" id="5422861at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="389" mass="43968" checksum="B9BEB6D204D71162" modified="2020-04-22" version="1">MGRNDDNERVVKPKKEKKPQIPKEQRVRKTKVPKDKDPHRTDKPEVPLMNRSVHAKWGALFRKHLGVLEAHCKALDRVQQAMRSEMARLSEEEKREWELNREGPWRILCGLLDRGRDTLVSGRTMARFVLPPRLIKDRKGLGVLGTSYEPLVPQLDARLAAETNGTTKKDESSDSDSSSDSDSDSDSDSDSAEDTGCEDEDVEMEDAPASEVEKSAAASAPVEVESNPYFVVDTVPTPVSNLNKKEKKKSKKEKEKIIEEKKVEEEVNFQAVEAQLQAEVAAGMKAKEEKREKAKKEKKRKRDSMGEESEGKKAKKEEEGGDVKERETEEAETKEKKSKKDKKRKADDVAEEDEQIDGKRKKKSRILDIVFMESHLITQDSFGELGIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2Z9</accession>
    <name>A0A5N6K2Z9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">6-phosphofructokinase</fullName>
            <ecNumber evidence="4">2.7.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">EYC80_002160</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="4"/>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2Z9"/>
    <dbReference type="OrthoDB" id="537915at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005945">
        <property type="term" value="C:6-phosphofructokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070095">
        <property type="term" value="F:fructose-6-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061621">
        <property type="term" value="P:canonical glycolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.450:FF:000010">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697:SF4">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="14">
        <location>
            <begin position="15"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAB8296742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="214" mass="23192" checksum="DF03F1F65272A241" modified="2020-04-22" version="1">MAPQPPPPLEGKKRRIAIMTSGGDSPGMNGVVRACVRMAIYKGCEPYCIYEGYEGLVQGGKLIKKMGWEDVRGWQSEGGTLIGTARCMAFYERPGRLQAAKNMVLNGIDALIICGGDGSLTGADKFRSEWPGLIKELIEKKELSEQQVAPFKHLNIVGLVGSIDNDMSGTDATIGCFSALGKICEMVDYIEQTASSHSRAFVIEVMGRHCAKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K386</accession>
    <name>A0A5N6K386_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_002254</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the pacC/RIM101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K386"/>
    <dbReference type="OrthoDB" id="6155966at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000458">
        <property type="entry name" value="pH-response transcription factor pacC/RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001875">
        <property type="entry name" value="pH-response transcription factor pacC/RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050806">
        <property type="entry name" value="pacC/RIM101"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC/RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257:SF1">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC_RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="95"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="368"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="490"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="589"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="368"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="392"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="425"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="490"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="552"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="593"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="608"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8296842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="635" mass="69045" checksum="030D2DD6DA169049" modified="2020-04-22" version="1">MSSQDQQQQQQQQQQQQQQQQQQQQQPSQAQASTASSSNTDNTSATASIQQNVVADDSLLCQWEKCSERCPTPESLFEHICEKHVGRKSTNNLNLTCGWNSCRTTTVKRDHITSHIRVHVPLKPHKCEFCGKAFKRPQDLKKHVKTHADDSVLLRSPEQPGGPNGGYRQGGGKANPMGYYEHNASMHPGSAGVYGNSHHGAHNGYYAPAPPQPSSYGGGQGYYQMSHNPDLGQHAAWDERKRNFENLNDFFGAAKRRQIDAHSYQQVNQRLMQLQGIPIGTGGGISDYIHSAPQLVPVDGHGGHGGQGHGGPMPPHQYSLPLPNLRTKNDLNSIDQFLEQMQSTVYESSNAAAAAGIHQPGAHYTHQGINFRQSHSPPQTQIHNIGSMPPHVSTSYASAPMTATHSSHSVSSGTPALTPPSSSVSYTSGNSPMSSSGLSPVSRHSSASTAAYPNLPAVSLGYSPHHSATAPTSTLGTNFDSDLRRRYSGGVLQRSSGGLSSSQYRESMEADTIGSPTPSPKETTPRPESIKTDVSNNIDPALSSVGSPTADRSIDSGESARDRAEEAWIENIRVIEALRRYVSERLQNGEYVKDEEEEEEEDVSMTGTDREVTPTKTEEKPSESLYPVLRTDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4W2</accession>
    <name>A0A5N6K4W2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4W2"/>
    <dbReference type="OrthoDB" id="421121at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="167" mass="18100" checksum="BDA291F469FCA7C5" modified="2020-04-22" version="1">MNPQVARNYPSQQLGATPGYGNPPFEPSPQTGRSNRPAPLPYRSSRILNSSSTLAPPHRAYPVDSNEYQRPILVGRSLSDQEFGEQHMLRRKTPNGTLAAGYDGTPVQWSSKAPALKHVVLDASGASIFSDGSNGMADPFILLTNWILGSNSTPASLPTWPWPNGFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4W9</accession>
    <name>A0A5N6K4W9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_002708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4W9"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF0">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8297363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="25478" checksum="F00B27C50B8DBC50" modified="2020-04-22" version="1">MALIESLPYSLSEAGPEELDGVGNYIVEVLAQGGSKHSALTIYLLDTHSYSPDERSFKGYDWLKKNQIDWFKQTAEGLRKSHEGYSHIHMDLAFIHIPLPEYRDDALYKEGEWREGVTAPGFNSGFRDALVEQGVVMVSCGHDHANEYCSLSRKEDNTPALWMCYGGGAGFGGYGGYGGYHRRIRLFEIDMNEAKIVTYKRLEYGDVEKRIDEQIIVEGGKPIGPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K584</accession>
    <name>A0A5N6K584_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K584"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052594">
        <property type="entry name" value="J_domain-containing_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="24"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8297724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="304" mass="34854" checksum="12FCC715AC781C85" modified="2020-04-22" version="1">MIERDFGTLSDKDDVIQSILNEEDLYKILGAQRSATCAELRRCYLERSKICHPDKIPFHPLSTRAFQRLAFSFEILKSPSSRRTYDSASFTSSSSPATTSLPTKHPSPSLASDNLFRTTVSSLIHDFLTGDFITIRSLLSSLNSQYPHLMNTDVTSSVEIAFVKVRELVMRGRIWALLIYIEMRRIWRVQKRLMGLRRWDLVGKARMFVLLVRVVVAVPVRVDRALRERVEREQRARKAGLETRGEGSKGEEEWRGGILNERVCKVLEFIIGDAVVSFVDVVFVLVDLEAEKRDPILECNYKWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5C0</accession>
    <name>A0A5N6K5C0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5C0"/>
    <dbReference type="OrthoDB" id="408954at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="264" mass="30627" checksum="D1B4029F64386F91" modified="2020-04-22" version="1">MNSYGVQVRVTKKRGIPFNLEGEKKKKKKKHKKRRLKNKSHCRNHFSILFLLHRLLPHLTSLAHSNHHSLTHSLLTFFILSFFSTFLLSYLILVLLFHISLITSTHSFVCNTITAAINQLAILSPKNQQIDTCTVLQYNPIFYIMTNFTTLQINTTTMSDLPPLPHYTLTPLQPLIPYISDFYLSLILPIAAYWIVSLAFHLIDTLDLWPQYRLHTPAEILKRNHVSRYEVARDVIIQQIIQTIVGANTHSTKGFTFYLKSNWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9A7</accession>
    <name>A0A5N6K9A7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001378</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9A7"/>
    <dbReference type="OrthoDB" id="6129702at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="180" mass="20214" checksum="3286F96E9C90008E" modified="2020-04-22" version="1">MSNEDFGIKHFPADKSHFFRNDGKILTWEEYFIGKIVGEPLQIFSSPEDLHGISQTSFTPPQKYLQASPTSNEIIRFQFSKICTHYDFERHGPGKPYCMVLKVGGVDGRKEDMMAFEFDGFWWWLDVPVRQLGTRGQTVGLFAITSVDGEGARGLSKSGYEGKKGRCGMGFDGVAVWVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9D7</accession>
    <name>A0A5N6K9D7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9D7"/>
    <dbReference type="OrthoDB" id="3642826at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="85" mass="10112" checksum="CAF44B98DF855670" modified="2020-04-22" version="1">MQIDNDVILCAVEQRVLLGLGGPILHFLILFLSFFHISFFLYHYYITCIHRYVQLAFYIYIISFYMTDQRVEESLGRDRIVLGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9E4</accession>
    <name>A0A5N6K9E4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9E4"/>
    <dbReference type="OrthoDB" id="5398233at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="120" mass="12768" checksum="DAD814DFBC54BFF6" modified="2020-04-22" version="1">MDTEYTGESSTQGEGPVSTTWSYENGLSPAPPRRGSAALLQDIGGLLGPRTRVHRYSSKGYELETITQDRSVGSPTSHPSQLGSTSNSNPQPQSEARPIDELGRQQANLTLQDVGGLLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9G1</accession>
    <name>A0A5N6K9G1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_000075</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8299826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9G1"/>
    <dbReference type="OrthoDB" id="413460at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18000">
        <property type="entry name" value="DEXHc_ERCC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="433"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="47"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="224"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="100"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="226"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8299826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="634" mass="71258" checksum="4073A57C1DA9F833" modified="2020-04-22" version="1">MDSSTKSRDTHDHSNHIKSESMSPPPQNIRLHREHTDTIEEAAAAVADEALLSDSDADTKAQPQDEASALAGLTENVRNQDDLERDITNQANQVMIEQEDQRDQKRIEKVENSIEKLESQKHTQERRLNGLSNNPLMRQRCADEISRIKTEISDLKKDVADIQKRIDERHQYDDSHPGAEVASASRRMPNESQREFLIRTGKITPFQQDSAAATDHVQSALSDALMDAEEKGDVDEPSDNTAEPRSHQNLRLPGFGDVADSTISTTEHEFGLRPRKKRLVNGASAHVSSTRSPSADDDTFTPEHSADEEEEFDDEDDEEALMTARTTTRKRSKPSKARTDEAQSLAGIDDGNEDMFQARLAGWVEKRSAARRQHLEHNPGNEEDLAAQNSSEKEWFKPCPGQPDHQFENGLKLPGDIFPALFDYQKTGVQWLSELYNQQVGGIIGDEMGLGKTIQIISFLAGLHYSKKLTKPVIVVAPATVLRQWVNEFHRWWPALRVSILHSSGTGMLNVKNEGRLEDEEDDILYGQTTKKAPKSQKLAQKIVDRVVKNGHVLVTTYAGLQTYSDTLIDVDWGYAVLDEGHKIRNPNTAVTIYCKELRTPNRVILSGTPMQNGLIELWSLFDFVFPMRLGTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9G5</accession>
    <name>A0A5N6K9G5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8299805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9G5"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8299805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="113" mass="12010" checksum="379242CF73239809" modified="2020-04-22" version="1">MVATDVASRGIDVRNITHVLNYDYPNNSEDYIHRIGRTGRAGQKGTAITLFTTDNQKQARDLVNVLTEAKQVIDPRLAEMTRFGGGGGGGRGYGGRGYGGGRGRGGGGGGRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9G6</accession>
    <name>A0A5N6K9G6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Flavin prenyltransferase PAD1, mitochondrial</fullName>
            <ecNumber evidence="6">2.5.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PAD1</name>
        <name evidence="8" type="ORF">EYC80_001216</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for the ferulic acid decarboxylase FDC1. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dimethylallyl phosphate + FMNH2 = prenylated FMNH2 + phosphate</text>
            <dbReference type="Rhea" id="RHEA:37743"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:87467"/>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
            <dbReference type="EC" id="2.5.1.129"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Oligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the UbiX/PAD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.129" evidence="6"/>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9G6"/>
    <dbReference type="OrthoDB" id="5428259at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106141">
        <property type="term" value="F:flavin prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1950:FF:000001">
        <property type="entry name" value="Flavin prenyltransferase UbiX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="entry name" value="Flavin prenyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01984">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004507">
        <property type="entry name" value="UbiX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004685">
        <property type="entry name" value="PRK06029.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00421">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43374">
        <property type="entry name" value="FLAVIN PRENYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43374:SF1">
        <property type="entry name" value="FLAVIN PRENYLTRANSFERASE PAD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="Homo-oligomeric flavin-containing Cys decarboxylases, HFCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1 6" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavoprotein" evidence="7">
        <location>
            <begin position="17"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="25"/>
            <end position="27"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="102"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00060793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8299101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="221" mass="24490" checksum="91904AB733C15EB1" modified="2020-04-22" version="1">MHANETSNGTNGVERRKRIVIGMTGATGAILGIKLLTTLRRLNVETHLVISQWAEATIKYETDYTPANVRALADHVHSNHDQAAPISSGSFHADGMIILPCSMKTLAAVNAGYCDDLISRAADVMLKERRRLVLAVRETPLSEIHLRNMLDVTRAGAIICPAMPAFYTKPDSIDDLVDQMIGRIVERSFMNEICTNISALALELRVLLEEWGVEFREIHVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9G8</accession>
    <name>A0A5N6K9G8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8299774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9G8"/>
    <dbReference type="OrthoDB" id="47785at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="273" mass="29424" checksum="AD03C756D5485DB6" modified="2020-04-22" version="1">MSDSEADEDLKRAIALSLQTSSPVPIHGKNLIDLTISDNENDNINNNNNNDDDDLDAPVTTHFKFSQAQHVPNTSTGIEVGTSSQVSSQPSATILNSLNPPNLASKKRKASVSSPASSLGEHRQPKASRSGSTLCGEPDERHRNKSTGRKSTENGADHALDKLARRPANPKSDTDIGTSVIYGKLPIDVQSGGDVSGAGIQFPRGIVKKTWADGFPREDDIKIEEVLQHSTLQHAVLSAFQVEPGWVMSKLLTTTKVIWVLQAKTEAEFKLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9K5</accession>
    <name>A0A5N6K9K5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9K5"/>
    <dbReference type="OrthoDB" id="5596422at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23814">
        <property type="entry name" value="UEV_AKTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="40"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8299141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="356" mass="39779" checksum="7E285CB32D54364C" modified="2020-04-22" version="1">MASQRLSTLSTVRKQHLLVEFSSLKYACPHGVFMSLTPGDPTLWSGVLFVRKGPYAPSILRFQISFPTQYPALPPLITFSTDIFHPLITPLTTYMYSTDTQSDGTVSATDEERLPPGGFSLRDGFPAWFGRKIRKDAEHSTPKKAGGSTAESEAMSSPGSGISSPGKTADGIRVGVYEILRYIRRTFDDELVLDKVPLEAAGNPGAWHAWKSYRIEIGKMTAEKKGPDFKDPTSPVVAREPGEWDWDGVWETRVKKGIEASTAETVLYGLGADDLIQFLNFDQERVEQIREQIKESTDILERRSVHVRPTIVSSIDTPVHTILSLINLRTSYMELEFRLHKENFSTPSMICFFVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9L0</accession>
    <name>A0A5N6K9L0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pumilio homology domain family member 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_000061</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PUF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8299812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9L0"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000004">
        <property type="entry name" value="Pumilio homolog 1 isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF12">
        <property type="entry name" value="MATERNAL PROTEIN PUMILIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUM-HD" evidence="10">
        <location>
            <begin position="520"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="542"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="578"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="614"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="650"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="686"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="722"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="758"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="797"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="394"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="872"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="38"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="135"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00060736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00081811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8299812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="922" mass="101235" checksum="5A72AB8E55299568" modified="2020-04-22" version="1">MSSAAAKRPTGTMNTQRSTRFGDFSTAPGRNNSDDRTSQSTTLGQTFGNGGTWQPSSGIWGSNTIGSGFANTKRDSSRSRADNDGFPDAPSGSGALAASSEADPWVARANGPWNPPDTTSPTLQSSHSGSASPSHVRNSIPSQTPQSLLELQTYQQSRPAIGQGTSFGRPQPKSSLDPSSGSFKFSRKPSFGFNEDKENSSQFSSNQDSAYDIDVSSRAFRMDQLGSQNTGFLGVGSASRDGSMPPSRASEVGLNNLTFVNGNPNFGSIGGHTPSNSIHSHRPSFSAISGSFAQTNSSRYSDLTAQTEAELREKFAGFGLTNDIDPTNISHINNTSSSSYSPTHQNFSQQAFQANGASAMWNDGSSAPKALSNYDNFSNQAPFADQGYFSKSSRFDRGSVSPASSDYRRSLNSPKYFSGTPPTGPEQIYRPSSRAGPRIPQGPSELDRRLQNIQYSQHQTYLYGNGHFQGQYPPHLYDYSPQTFRQTNLPPYGYPMPLPPFPAQNIPTRPAKDQDVGLGVRSVLLEEFRSNAKSNKRYELKDIYQHVVEFSGDQHGSRFIQQKLETANSDEKEQLFREIQPNALQLMTDVFGNYVIQKLFEHGNQVQKRVLAEQMKNHVMELSMQMYGCRVVQKALEHVLADQQAELVRELEADVLKCVKDQNGNHVVQKAIERVPTEHIQFVIEAFRGQVHVLATHPYGCRVIQRILEYCQPHDQERVLEELHQCASNLITDQYGNYVTQHVIQHGKPEDRAKIIKIVTAQLLTLSKHKFASNVVEKSIQFGSAEQRHTIVSLLTALHSDGTSPLQLMMKDQYGNYVIQKLLGQLKGAERTAFVDDLKPQLLALKKYNYGKQIAAIEKLIYEINSSAPTPLLTNGQNSPQSSSLPSANVSTIDDPTDSVSSGKTAIAVNEKSCPEVVISGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAP6</accession>
    <name>A0A5N6KAP6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SLC26A/SulP transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_000450</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAP6"/>
    <dbReference type="OrthoDB" id="431212at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005345">
        <property type="term" value="F:purine nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015853">
        <property type="term" value="P:adenine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015854">
        <property type="term" value="P:guanine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="XANTHINE/URACIL PERMEASE C887.17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337:SF1">
        <property type="entry name" value="XANTHINE_URACIL PERMEASE C887.17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8300238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="36220" checksum="D866D0C5A704713F" modified="2020-04-22" version="1">MARFCGAIDEDTQDFEGSAVAYLVDAFGISLGSFVGSPPVTAFIESGAGISEGGVTGLTAVTTGFCFFISLFFAPIFASIPPWATGCTLILVGAMMARACTEINWRYLGDSIPAFLTLAIMPFTYSIAYGLITGIVTYILLNISAWMLAKMSGGRIMPHDYELKDYWTYKVRGGLLPGWVKRATRGKRDFWREWDFDAEEVSSKVESVRGHKTRGSVTKSIKSHDVLSLRKDEIIGIPNLNGHGERTWEMPEMAFPKSVVGGIGEAIGGEERRGSTRTMSSIGRSLGRRQARVNGTGGGTFGVKNRNMNWVDGVDKLCDDIRCLEDFLEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAQ0</accession>
    <name>A0A5N6KAQ0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAQ0"/>
    <dbReference type="OrthoDB" id="10009287at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="79" mass="8677" checksum="C17ED81D89381281" modified="2020-04-22" version="1">MSFQDKVQGTISQIDKELSKYPTLNNLEKQSSVPKVYAFLGVIAFYFFFIFFNIGGQLLTNLAGLMTLSGSLTGLSSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAQ1</accession>
    <name>A0A5N6KAQ1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_000471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAQ1"/>
    <dbReference type="OrthoDB" id="45930at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045046">
        <property type="term" value="P:protein import into peroxisome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006966">
        <property type="entry name" value="Peroxin-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080:SF1">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04882">
        <property type="entry name" value="Peroxin-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8300267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="259" mass="28735" checksum="AE1AA43188E37A17" modified="2020-04-22" version="1">MAKFSELTLEVRKKVEGATPEDRQATRWLQYLLPPRDQEDFVIKESGMETMEPEIPSSSPVSPLRRLLDETSDLIDSPPFSHVLTMLLDAGFSTLVEQKIAQQSFKVPSQPEDARVAEVVEPKPVKLPLILAVLTRQAHSIGNGVPNEYLQAMEQVRELEAFAAVVYSSHENEIKPVDDFGSAILVPKTGLGETELVDIASNGQDSLIDVGTASRFENCTTSEIIQTREDIWNMGIITGQDFGHLVEAKEETSYVKIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAT9</accession>
    <name>A0A5N6KAT9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="5 6">2.5.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_000508</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = N(6)-dimethylallyladenosine(37) in tRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 7">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="5 6"/>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAT9"/>
    <dbReference type="OrthoDB" id="775260at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030666">
        <property type="entry name" value="IPP_transferase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="TRNA DIMETHYLALLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088:SF89">
        <property type="entry name" value="TRNA DIMETHYLALLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01715">
        <property type="entry name" value="IPPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039110">
        <property type="entry name" value="IPP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="431"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="434"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR039110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8300316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="465" mass="52343" checksum="3D57D1576E335C97" modified="2020-04-22" version="1">MNRVIPKDPLIFILGATGTGKSQLAVDLATRFNGEIINGDAMQMYEGLPIITNKITVDEQKGIPHHLLGFIPLDAETWTVGTFKKQASHIIQEIRSRGRLPIVVGGTHYYTQSLLFEDELVSSGKASGDVHDDHQLSIEELSNRFPILNAPTEQILDRLREVDPLMAARWHPNDRRKIQTSLQIFLTSGKKASDIYQEQKETRAIAQTVLNGKPTPPATFEIGSPLLFWVHAKSDILKLRLDKRVDKMIDVGLLDEVKSMETIRQQYIRTGTDLDLSRGIWASIGWKEFESYLQNLEDEGGNPTKRDALRDDSLDKMKAATRQYAKRQIRWISLKLIPKLVHENAIDKLYLLDGTDVSSWAANVSGPAIDITQEFLLGNDLPTPSKMSDLAGEFLNLEKSLQHSQSKAHWVPKKCEICHIVVMTEGQWQVHSTTRAHRRMAKKQQRGGANGRSPHKRESASPVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAU6</accession>
    <name>A0A5N6KAU6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAU6"/>
    <dbReference type="OrthoDB" id="68483at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="358" mass="39906" checksum="B2871E2D50612FB6" modified="2020-04-22" version="1">MHPWVTINGTDPLLPKEENIANLVEPPSETEVNHAITIKMRGLLAVMKAVKKFKNKLEQRRPNAISETLGKGIRVLHPSMGMDEQHESALYRSKSADLEDRRFVEAALATEGIHHDGTYPSADGIRTMTSRMDSSSTIVADEEPADKMLTQQKITKTNSSDLVTKRPELREQHSGDKGHAHDPLDEEPLYLGIGAGIGDGDSLDAPVQGLIAESPTAAEFSIYDTAYQQEVERIRAAQGHAATVYLTRRVDHKKEYKADRNMINLPHQADMKGRIQEGWKGLVDRAQENKDELSLHEKLTEGHQAFSDLVAKAVENTRDMGRDISERGGTTFDNVLHGAMEKREEKVEGEEKEKDEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAU9</accession>
    <name>A0A5N6KAU9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAU9"/>
    <dbReference type="OrthoDB" id="4489171at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="199" mass="21763" checksum="524286B4A73F4ECF" modified="2020-04-22" version="1">MEAVPGVTPLPLQGFVRDDNIAFSEELPSPPVDTPDGSQFSPRSPGKRKRAERSSSVNSSEDGQYNGTEREGWGDISTTTVSATPPNRLAQSNEVIMGVDPFNDGKAQEMQERSGSGMLQNFAGNSVKKEVGNDSMDIEDTEDTESDEIQRAEAHISVNQKDTGAVKRVGWMTFQSTYSHIVHNEKYNTPAAQSTKHEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAV8</accession>
    <name>A0A5N6KAV8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Alpha-galactosidase</fullName>
            <ecNumber evidence="4 7">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_000494</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAV8"/>
    <dbReference type="OrthoDB" id="5795902at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000111">
        <property type="entry name" value="Glyco_hydro_27/36_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452:SF75">
        <property type="entry name" value="ALPHA-GALACTOSIDASE MEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00512">
        <property type="entry name" value="ALPHA_GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024981091" description="Alpha-galactosidase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8300298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="127" mass="13941" checksum="EC392D19F6ADF191" modified="2020-04-22" version="1">MSLRNIFGAATALLAFGAEAVNNGLARTPQMGWDNWNALGCDVSEELLLQTADLIVDYGLKDLGYHYVILDDCWSNGRNASDNNTLVADAKKFPQGMKAMAEAIHDLGLGFGMIRKCRREIFCIRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAW2</accession>
    <name>A0A5N6KAW2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cation-transporting P-type ATPase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_000507</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAW2"/>
    <dbReference type="OrthoDB" id="158672at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000114">
        <property type="entry name" value="H /K ATPase alpha subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000083">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF21">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="373"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="860"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="886"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="930"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="983"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1030"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1062"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="11">
        <location>
            <begin position="112"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="23"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8300313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1147" mass="127428" checksum="463319BCFE5E5C0C" modified="2020-04-22" version="1">MDEKAVYTSAEERDDEVFHVAPRPEARIRFNAQDEEAGRQTSTLPRMARTNTNSSQLSTASSRRRRVSIDPATALPITYRTVSFAIEETKEKQKVEADRAKKDAAAELGDLEWHTLSTDEVISRLEASLAHGLSKEQVDVKTKEFGKNMPSKPPSDLFSRVFGYLFGGFGSVLLIGGILVTITYEPLGGSNPVLANLALAIVLYAVFVVQALFNAWQDWSSSRTMASISGMLPDDCFVLRDGNRVELPASDLVPGDVLYIKSGNKLPADVRFVEISSDARFDRSILTGESQPIPGSVDNTDLNYLETQNIGMQGTHCISGSAIGVTTGMTTLQKEILRFIIIICSIMVFFNIVVIICWGAWLRHSHPDWITTAGLIVDIVTVAVAFIPEGLPIALTASLTITANIMKSNQVLCKSLKTVETLGAVSVICSDKTGTLTKNKMFATECSVAERTMTPDQAVEFQNSNGSTTNSVAQLRSLAGLCNAGEFDAATLHLPLAERKIAGDATDQAVLRLSETFGEVRQLHMLWKKTFELAFNSKNKFMIRTLALSEPQGLELAVSPKELAVWKREDLLLTIKGAPDILVERCTKYVGEDGHLYPLDVDMKTSVDEIKNRWSSEGKRVILLARKVLHGHQTQHKPEHNTFEAEIMRQAGSDLILVGLVGIVDPPRDEIPEVVQVLRRAGIRIFMVTGDFKLTAQAIAIECGIISSPPDMIHDISRLNRNGVETPKSISSGVISEKDTDHKHGYTRSITLSGPELITLNDNQWDQLCQYEEIVFARTTPEQKLRIVKEFQKRENIVGMTGDGVNDAPSLKAADIGIALGSGSDIAIEAADMVLLDSFGAVVEAVKYGRVVFDNLKKTIIYLLPAGTFCEFLPILTNVILGLPQILSSFLMIMICCLTDCAGATVLAYEKPEADVLLRKPRDVKKDRLVDWKLLFHAYVFLGMQEAIASFAMAYWYCQRKGVTFSILWLGYGKYPPHLSDEYVQSVLAVASSIYFVTLVIMQWFNLMATRTRRLSIFQQPPAFNKATQNLWLFPAIAFALVVIFIFLYIPGLASAIVSSPIPAEYFFFPLCFGMWILFTDEVRKFCVRKWPEGWLARLEGKVCILRERCRDIIGDLAELSLFEHITKGKNILRHFIKEHRCRRAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAW4</accession>
    <name>A0A5N6KAW4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fork-head domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_000459</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAW4"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00059">
        <property type="entry name" value="FH_FOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000260">
        <property type="entry name" value="Forkhead transcription factor (Sep1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045912">
        <property type="entry name" value="FOXJ2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46078:SF2">
        <property type="entry name" value="FORK-HEAD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46078">
        <property type="entry name" value="FORKHEAD BOX PROTEIN J2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Fork-head" evidence="8">
        <location>
            <begin position="218"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="218"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="181"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="309"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="586"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="688"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="348"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="586"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="596"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="696"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8300252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="721" mass="79626" checksum="962048349FDD9B16" modified="2020-04-22" version="1">MSSSRYTQQPLQIYQDPVTSYDSAPMPSTKNSSNPKKSSPLRTIKSTNSKRNIIFNPPQNGPSKRSPLKSQSHISSSPSRAPFGNKLNMVPMPPPPGSRYNTDSIAKKQPFQSKYKSAPQKALFTTFMNTQPQGKENHTHSPYPSQPRFRDDLSSSNFSLEGLYGQKPSLKRSLMEAAPIQEAKAQNKSKAEEGNEASGPRELPEPDSFPPIHDDGFKPSHSYAQLIGMSILRAPKRRLTLAQIYKWISDNYTFYNATDAGWQNSIRHNLSLNKAFIKQERPKDDPGKGNYWAIQPGMEYQFIKEKTTRKPAGPNENLPVLNTALTPVDPPVDPPEPTPPTPMFKDLPSSSQDVSLPKSTFALPDNELPPIPELSSDATIPASEFNQEAEDKEDHAPPSSPQIQSSPPTGMMHSSPPVARRAPRRNHTPPPVPRFPSSSQTRSHKRKFASMDDTDRPRIKRGRAEEEIARLRGSSYDSPSKGRNFSGFAPPSSSPLRRAQPHDNYQMLPPLTPAVKLKAPIKPPPSISPNTNLRMHRDRVRELVGSPIRGLTVLEDSAWSPAFNLDNSYMFGGYVSDFDIFQDSTASLPGTSNGSPEKRSTKRPRADRSKSANILSDVTNSNLNKSVTSTPILKLTPSLGGPSAFLSPTKGGLNFMDSPCKPNNNSPLKFDSPILNLDYAGFDITQRFPKIGSGAQQQQSRNSSKNQPPRPSMGRSSTTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAX5</accession>
    <name>A0A5N6KAX5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAX5"/>
    <dbReference type="OrthoDB" id="4489171at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14273">
        <property type="entry name" value="UBA_TAP-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055335">
        <property type="entry name" value="Ucp6/RUP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39597">
        <property type="entry name" value="UBA DOMAIN-CONTAINING PROTEIN RUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39597:SF1">
        <property type="entry name" value="UBA DOMAIN-CONTAINING PROTEIN RUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="462"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="645"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="727"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="490"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="675"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="697"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="734"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="757"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="820" mass="92006" checksum="EB25EB4CCA737957" modified="2020-04-22" version="1">MAAQPTPQDVQSFLDTTGQMNRQEAIQRLKGNNNNVQQAINEYYDDLETGRNQNRYTWDDSQFSMDREGAGGQQAFSVQGADEFKPSYSHFESAAPSRPPSRTSDNKSPLSKAVDLTTHNDSTVAFTNFGDNNDTELQQALAASMADAGLPPQQSGVIDSEKPFFGPATRADYGDNWAMVPISTVKEIYVDPEPTDRIRDTVNQVPAFLKPSGEGHRLGALLTIYYNIPLAREVFLRRENVETYYPYQAGWWNGRPVEKPLASFQKDPYTVAEDRRFGQELQKVMAFLDKTERSYGSADVITTLPFMQQHRGDDVEAEFFMSFYRLMQGNDLCKHIFSTGVLGLDTDLEEQPTKFAIFDLTLPSKDSLIQNLYDLQDEALWGNCPFTLARTPYLAHIGDVVAFRMKGDKLNDQKGVEVPLVWYPDRYLEFAGKDSLNMRADKQNLETLLVEDVLKIALNHDQNEIPRSDEDGDNQATDTPIGGPKSGELSKKLRKLMHVVNEKLKRLQDQKEKAKEAWRQLSELYTDQSKTSQTLHRYSLRGVSLNKETTYICTRVEPDLIDMGLSDDKCISPSDGQWWRIHYSTSSPPQISVEKTTPEKVLEDVKTENETAILVYASDQAMEAVPGVTPLPLQGFVRDDNIAFSEELPSPPVDTPDGSQFSPRSPGKRKRAERSSSVNSSEDGQYNGTEREGWGDISTTTVSATPPNRLAQSNEVIMGVDPFNDGKAQEMQERSGSGMLQNFAGNSVKKEVGNDSMDIEDTEDTESDEIQRAEAHISVNQKDTGAVKRVGWMTFQSTYSHIVHNEKYNTPAAQSTKHEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KB10</accession>
    <name>A0A5N6KB10_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_000533</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KB10"/>
    <dbReference type="OrthoDB" id="331544at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000304">
        <property type="entry name" value="UDP-glucose 4,6-dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="47"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8300348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="430" mass="48140" checksum="84054BA1F2737D0D" modified="2020-04-22" version="1">MASNGTTPSSANGEQNKFFEDFGVWKEAPILTGSTKFTPLPDVKNIMITGGAGFIACWLVRHLTLTYPDAYNIVSFDKLDYCASLNNTRALNDKRNFSFYHGDITNPSEVVDCLERHNIDTIFHFAAQSHVDLSFGNSYAFTHTNVYGTHVLLESAKKVGIKKFIHISTDEVYGEVKDDDDDLLETSILAPTNPYAASKAAAEMLVHSYQKSFKLPVIIVRSNNVYGPHQYPEKIIPKFSCLLQRGQPVVLHGDGTPTRRYLFAGDAADAFDTILHKGTMGQIYNVGSYDEISNLTLCSKLLTYLDIPHSTQAELHKWVKHTQDRPFNDHRYAVDGTKLRQLGWDQKTSFEDGMAITVDWYKRFGERWWGDITKVLTPFPTVTGSEVVGDDHAVEELKEDIVVDADDNTVLGKKRKLNGVSSGLEQTVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KB12</accession>
    <name>A0A5N6KB12_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Superoxide dismutase [Cu-Zn]</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_000566</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KB12"/>
    <dbReference type="OrthoDB" id="2015551at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006801">
        <property type="term" value="P:superoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018152">
        <property type="entry name" value="SOD_Cu/Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="SUPEROXIDE DISMUTASE CU-ZN -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00087">
        <property type="entry name" value="SOD_CU_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Superoxide dismutase copper/zinc binding" evidence="4">
        <location>
            <begin position="81"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8300386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="198" mass="21575" checksum="CAA54001FB494EEA" modified="2020-04-22" version="1">MALISNRFHPSFSVILRRTANNNSNNTSAAVFSSPHPPSPTQDNNIKTISKPSPKPSNHQFQSQFVKMVKAVATVRGDSKVSGTITFEQANESSPTTVSWNISGNDPNAERGFHIHQFGDNTNGCTSAGPHFNPHGQTHGAPTDEVRHVVLSDVPLSSTPELMISVRERTKSLRRLVTPEPDQLAVCSSLSIRILAHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KB13</accession>
    <name>A0A5N6KB13_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000496</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the complex I NDUFA12 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KB13"/>
    <dbReference type="OrthoDB" id="274641at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007763">
        <property type="entry name" value="NDUFA12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12910:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12910">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B17.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05071">
        <property type="entry name" value="NDUFA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="225" mass="26392" checksum="A2E4414BDE970979" modified="2020-04-22" version="1">MSTIMRTLRNLRRVGIKDALHQMHYQGDTKAGTLIAKDRYGNKYFENLEDELPLRTRWVDYKDDEFSPCQIEPGWHAWISYMVDKPPTEDPLLQTKVRPWELPDHRPNFTMSRGAFKTYSTVKPKITAWTPETIGIARVPTSSANLHKFQSELSESWPVYIIDMWLSLGSVEIAREVKYSCPFGYAFHHATRLGIYIISLYIFKSRFYCYPCPFTSLMYNQNIFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KB15</accession>
    <name>A0A5N6KB15_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_000512</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KB15"/>
    <dbReference type="OrthoDB" id="19692at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23811">
        <property type="entry name" value="UBCc_ScCDC34-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000063">
        <property type="entry name" value="CDC34p Ubiquitin-conjugating enzyme (E2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="5"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="176"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8300321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="234" mass="26147" checksum="13CD035A74474A8B" modified="2020-04-22" version="1">MSAVAAKNRLMAEYKGLAKEKWVNIELDEGALFKWEIGLLVINDESAFNGAYLKAEMTFTDNYPFSPPTFKFLRPIQHPNIYPDGKLCISILHPPGEDEQSGESASERWSPLQGVESVLRSILLLLDDPEINSPANVDAGVLYRDNREKYNQKAKETVAASKQDIPADFEMPTTLEVAPPAKPVNDDAFWVESDEEDDFGASDSSGEDFGMEDGDEEEDGEEQEEEEGEDEMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KB17</accession>
    <name>A0A5N6KB17_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KB17"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="93" mass="10575" checksum="70A6003140176DB9" modified="2020-04-22" version="1">MGTLCTNPRFTGVQEEEEDGRRCGNLPDGTVSKGLRYSNNIIPLMPDDNDEEAIENDALAARETVEREIEEHRRRAAYTKSVFHHAQTDRDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KB21</accession>
    <name>A0A5N6KB21_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_000574</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KB21"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="52"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8300396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="544" mass="58159" checksum="3BF21024692C23A8" modified="2020-04-22" version="1">MSSSHHSDEETPLLAEPATFPSQSSSPSQDPLVSAEATIIPDVPTTKRLVITMGAIWVGVFLGALDSTIIATLSASISTSFNSLSLLSWLASAYLVANAACQPLSGRLTDIFSRRTGLIVSNVLFAAGNLICGLANSEWMMIFGRVVAGCGGGGLMAISTFVGSDLVPLRKRGVVQGIGNICYGTGAGLGGILGGWINDTWGWRMAFLAQVPFIVVSGILVASLVNIPPKKSEKSKLSRVDFMGSFTLVLTLVLLLLGLNSGGNIVPWNHPLVYISLPLSLLSLFGFIYIELYRASEPVIPVRLLANRTVFAACLANWFGTMTIYTIIFYVPLYYQVRGASTTASGMRLIPQSIGSSIGSLGTGIIMNRTGKYKAISLVTFSMLVIGTGLLCTMDSHSLDWPVYIYLTLTGIGYGATLTTTLLAIISAVSHDHHSVVTSASYAFRSTGSTIGITIASAVYQNILQTDLWAKFGNLPDAEEIIGKIRDSFDELNKLPEGWKEGVTESYMHAFRGVFAAAFALAVLMAGVGSLMRQNVLHERLDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KB58</accession>
    <name>A0A5N6KB58_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Superoxide dismutase [Cu-Zn]</fullName>
            <ecNumber evidence="3 10">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_000566</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="10">Binds 1 copper ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="3 10"/>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KB58"/>
    <dbReference type="OrthoDB" id="2015551at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00305">
        <property type="entry name" value="Cu-Zn_Superoxide_Dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.200:FF:000001">
        <property type="entry name" value="Superoxide dismutase [Cu-Zn]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018152">
        <property type="entry name" value="SOD_Cu/Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="SUPEROXIDE DISMUTASE CU-ZN -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00068">
        <property type="entry name" value="CUZNDISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00087">
        <property type="entry name" value="SOD_CU_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00332">
        <property type="entry name" value="SOD_CU_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="9 10" id="KW-0186">Copper</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Superoxide dismutase copper/zinc binding" evidence="12">
        <location>
            <begin position="81"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="191"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="191"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8300384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="221" mass="23341" checksum="9E637E0586CD9514" modified="2020-04-22" version="1">MALISNRFHPSFSVILRRTANNNSNNTSAAVFSSPHPPSPTQDNNIKTISKPSPKPSNHQFQSQFVKMVKAVATVRGDSKVSGTITFEQANESSPTTVSWNISGNDPNAERGFHIHQFGDNTNGCTSAGPHFNPHGQTHGAPTDEVRHVGDLGNFQTDAQGNATGSKEDSQIKLIGPFSVIGRTVVIHSGTDDLGKGENEESKKTGNAGTRPACGVIGVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KB65</accession>
    <name>A0A5N6KB65_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_000553</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KB65"/>
    <dbReference type="OrthoDB" id="1925334at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000009">
        <property type="entry name" value="Cytochrome b2, mitochondrial, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF104">
        <property type="entry name" value="CYTOCHROME B2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="4">
        <location>
            <begin position="102"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8300371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="229" mass="24827" checksum="10285CA0D0D73D54" modified="2020-04-22" version="1">MGISVQEISQHNLPSDLWIVVDNTVYDLTEFAPEHPGGSGIILKYAGRDASKAYSEIHASSLISSSLPSSKIIGTIDLSSITDEWAKPPPEVSKALTPGSKPSLDNFINTYDFVSAAESLLTPKTWAFYSSAATDLITKGRNTSTYADIGLRPRILMNVKNINTRTTMLGNELNMPLFCSPAAMAKLVHPQGERELARGLKSAGLAMTVKSFEYPRCGERASNIFPTLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KB74</accession>
    <name>A0A5N6KB74_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KB74"/>
    <dbReference type="OrthoDB" id="4523179at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="191" mass="21369" checksum="B645BEBA4B2AFB76" modified="2020-04-22" version="1">MNFIRGIIEPNAKLKEHSNKHTNTSNKHIHFQTYYTSSLSLNQKLYFFQDTGGVKKDGLLEQKAGGSIPDDQEKVIVEGMHSWSSGKYTASVNRLTKIVVVKCHEKVATKDAATKAINEQEQLVNSHIKKTKRDNDDDLVVDDDVDDDVNDDINDDIDNASDDDRVGWNDEEIISGGMEFSTGVLARPTVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KB87</accession>
    <name>A0A5N6KB87_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_000590</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KB87"/>
    <dbReference type="OrthoDB" id="446890at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140824">
        <property type="term" value="F:thioredoxin-dependent peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF78">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8300414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="87" mass="10022" checksum="9D8DB3844F54902E" modified="2020-04-22" version="1">MSSAASIYEFEPLNKKGEPTPLSDYKGKVLLIVNTASKCGFTPQFEGLEKLYKDVKEKHGDDFVILGFPYQLWSFLPHHEKGRCKWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCT2</accession>
    <name>A0A5N6KCT2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCT2"/>
    <dbReference type="OrthoDB" id="3944408at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="99" mass="11009" checksum="32D112DB340C6B38" modified="2020-04-22" version="1">MDSSTSPNSPIFPTPGVVSLNSSMSSNNMMETSFFGLPLHEQTGYKDFMGAGHRGEMTYCFDPWDQTVGRFGDIVNGIEDGGRVMVKREETYDEAYGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCU7</accession>
    <name>A0A5N6KCU7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Heat shock protein 60</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_003088</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCU7"/>
    <dbReference type="OrthoDB" id="1733909at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000001">
        <property type="entry name" value="60 kDa chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000592">
        <property type="entry name" value="PRK00013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009487">
        <property type="entry name" value="PRK12849.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009488">
        <property type="entry name" value="PRK12850.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009489">
        <property type="entry name" value="PRK12851.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45633">
        <property type="entry name" value="60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8301195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="544" mass="57501" checksum="BCF544329BC70F0C" modified="2020-04-22" version="1">MQRALSSRARASVLSGSTASKLRPLQQLRFAHKELKFGVEGRAALLAGVETLAKAVATTLGPKGRNVLIESAYGSPKITKDGVTVARAITLKDKFENLGARLIQDVASKTNETAGDGTTTATVLAKSIFSETVKNVAAGCNPMDLRRGTQAAVEAVVEFLQKNKRDITTSEEIAQVATISANGDTHIGKLIANAMEKVGKEGVITVKEGKTMEDELDITEGMRFDRGYVSPYFITDTKSQKVEFEKPLILLSEKKISNVQDIIPALEASTQLRRPLVIIAEDIDGEALAVCILNKLRGQLQVAAVKAPGFGDNRKSILGDLGILTNATVFTDELDLKLEKATADMLGTTGSITITKEDTIILNGEGSKDAIAQRCEQIRGVMNDPTTSDYEKEKLQERLAKLSGGWWNSSPQAAAGQALVGLKPANFDQQLGINIIKSAITKPARTIVENAGTEGSVVVGKLMDEFGADFNKGFNSATGEYVDMIAAGIVDPFKVVRTGLVDASGVASLLGTTEVAIVEAPEEKGPPAGGMGGMGGMGGMGGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCY0</accession>
    <name>A0A5N6KCY0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCY0"/>
    <dbReference type="OrthoDB" id="3506693at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="568" mass="63838" checksum="681FA5FA6969BFA4" modified="2020-04-22" version="1">MAKSVDTQSSTYKRVSRCLASIIRFHRANASKEGLCPQVIISCYRLRHRWSPKAQFYAQLQKEDFVRRVLDQMIEDHMLEEVSQTDKPSGRNLPATVEPSYILKSNCETESCKQGESCDDLLSTGIFGPNQVVFDSSLATPGNIGREYVSMSELEPNAARFFSPTNTNILGSSNEVPSNKRRRISGVNGSSSGVDSSNGVKENQVNLQSSSVASSALTHEVESAPRSSKIIGSNEANSNPEKLAREVANLPWLTQGLQELSERYPDDQYELVYENDLLQIRCHDCKGRLYKIHYQNCDVSNMEWHAKSTIHADRVEKRIAEGGGEVKLTDDVKKRREALETAKKTAPHRFRRVQHKPLAPIQPAVPENPTPQHPWATWNPSLLREISQQLRPNDQYQQSSHPGRVAHNAQQESELNSPSESRIQRLEQENIAQERTISALQNKLRTQQQVNNTHQSVIKDLILRVQALEKKDEQREPELTNLKCQIPVLQARADQRDREDDKIAKKVFILENGMEAIKGKITQLNSTSASGNQGDKVDGDGTEAVSSSDANADILKPSRGRPRKPFHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCY5</accession>
    <name>A0A5N6KCY5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial intermediate peptidase</fullName>
            <ecNumber evidence="3">3.4.24.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Octapeptidyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_003182</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal octapeptide as second stage of processing of some proteins imported into the mitochondrion.</text>
            <dbReference type="EC" id="3.4.24.59"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.59" evidence="3"/>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCY5"/>
    <dbReference type="OrthoDB" id="17530at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06457">
        <property type="entry name" value="M3A_MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033851">
        <property type="entry name" value="M3A_MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF79">
        <property type="entry name" value="MITOCHONDRIAL INTERMEDIATE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 12" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="13">
        <location>
            <begin position="1"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8301300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="443" mass="49071" checksum="D63E997910099237" modified="2020-04-22" version="1">MAKSPASVSQFLQALAKDNNQIVKGEVSELLKAKLSNSNASSTGLQPWDKDYYMTQILGSIRSHSRNSDFLSAYFSLGTVMQGLSRLFTRLYGVRLAPHETMPGETWNSDVRRLDVISETDGHVAVLYCDLFSRPGKSPNPAHFTLRCSREITIPELEEASTLLHDGLFKTDEEAANDGMATSRASGVLKQLPTIALICDFVTMSGKSSRPALLSFNEVQTLFHEMGHAIHSILGRTSMQNVSGTRCATDFAELPSVLMEHFAADPSVLSLFARHYETDQALPYEMVAEKLALDKRFEGSDTENQIILSMLDLAYHSDLPLSPTFNSTEVYHSLQREHGALPIDPPETCWQGFFGHLFGYGSTYYSYLFDKVLARRIWQVVFRGGEGGGGVHRDNGEKMKEEVLKWGGGRDPWKCLAGVLDDGRVENGDQKAMAIVGSWGAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KD66</accession>
    <name>A0A5N6KD66_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KD66"/>
    <dbReference type="OrthoDB" id="3516260at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="632" mass="71188" checksum="4208D1D98FF0C47F" modified="2020-04-22" version="1">MSLSKPVRHCPSNCRGCATFAAFGGERFPDQPPGSPLAKCYEYARAAGIIDGPSSSITDLVPAPLSIPEKSARRPISKPLHPSRQVSESREDALIRAAAIGTLTAADAKAEADAGIPRNTSQSEVRQITAPKALKLNLKLDQLGTKARYPQSDSRSQSSSPPYSGINYDVDDPRFPLGHAYIPPGITPLPNDPMFTITTNGEQYATTFVGRYAMRMYDAHRASGVDMRTYEVRGEWEKSGAKRWIFSLGADTDIGKVTKVLGKGKDVVMAAGSERISTSKLLREYENMGIAVENKRLEMENAFRDVEKAVKEGGWDRRPLVDGPLNTEAMQAIIQEIIRLRFDPLDYEGPDWIGGTTSISPLLPREQPLRVGCGKSGVITDDDNDETACTTYVRLTPMKQMEFSWYQRRNTNDSRRHQWSHYMRCILSDGSIRDFSMKDVYDSVNGKLSLLRKRFMFEESAANITLKFVWSQWRKMAREMINFEWFWDEDKRILVQGYSGHHDYEKDCDWIDEQMNNWRDCVEDDLEANCEAVKSGSLTMKEAKYAMIGGQLLRQWKEGPGIMISRTPGDEKWDGSILGPYTNDGASHINYLNSRIAFATRQTEEIEKMWVNGSATGEDLAERRESDKKKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KD95</accession>
    <name>A0A5N6KD95_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KD95"/>
    <dbReference type="OrthoDB" id="5973539at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116:SF1">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="197" mass="21946" checksum="741B823520E52325" modified="2020-04-22" version="1">MGKSIPFIDPLRPIILDPSTPPTKEDVCMDRMGLQRILSSQSFNTYIINTSIPADSYLLTLLHFNVIRALTINVEILKLPVGRMDDDILSPFNISSTSQYPPSDLLTLPPALQPTNLQISIEHHPEIDIFPFPQCRDNLLAALSEGDGWDDVGFCRDMLYGVEGGDGRTGLIVWGDPVGGEKGMMRKYFARISRAWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KEX3</accession>
    <name>A0A5N6KEX3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KEX3"/>
    <dbReference type="OrthoDB" id="3518224at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="548" mass="60109" checksum="3A6A7C099CC25D0D" modified="2020-04-22" version="1">MSSEHPKDLADCRAILIPTSIITPNTQTSNQGLTNSQSSPRLPLRPNAPTSFSSPLSSIPSVITSRASGGDRSFTPGSQQLCVLDSPGLRTPPQGLPSQYLQSPPLNTAPIPNHEVQGDYFQGHRPHTSIRSRNGLGETNASSIVATPLLATEEYQVSLSSKDSHIASDPHSCTTDSLPSILGQSNAPYKARRPSSDSLTMIKRPRRLTEGAKFQRKHRCKGTCTRGRERIVDKMAKDERDRNSRWGLPPIQVTPTAPEGIKIPNTRKGTGLSERRSKGRLMSEPAAPLVSRRWSSVEIGTRQLKLPPLLKKQPSDYMYGTSPIFRNGIFKSNPLGERNRSSSFTAGAGYNDIVRSLRERLTIRKLPNNHMLMPSAITLRRPSATNKSDMSSTMEASVVLTTPRTGSAMPSFSSRHPTFFENQSQDPEAYIITREDVEAVMELLQANLLGTQEFHTPVHAPRGSSVEDQSPRGTRLPSLSFTEKGVVPLSRPASCGIHKYTAQSENSTENSVNVLADFSKGFGRHWTAFRSRARTKCTRSHLGGTQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF93</accession>
    <name>A0A5N6KF93_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF93"/>
    <dbReference type="OrthoDB" id="3561891at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="113" mass="12851" checksum="CEA4E55C6662E41F" modified="2020-04-22" version="1">MEDTVMGDLKMEATEPKDAADATSPPMKYYKGRFKHSEKAYFLFLCRKHGIPDLRPEGRKEQHHVREQYALALTAMQAEATKHIKGDRGGERETNQERTGKEGARDQGCKRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF96</accession>
    <name>A0A5N6KF96_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF96"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="114" mass="13791" checksum="1A01B8FE14C4D31D" modified="2020-04-22" version="1">MEFGGSGFLGINDYLGSEAGFERTLRVKEAQECDSVQESNERRGLKWRGEERRGEERRGEERRGEERRERREERRREDRKERFEKMNRQDGQDEEDEDDEDEEDEEDEADEQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF99</accession>
    <name>A0A5N6KF99_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-phytase</fullName>
            <ecNumber evidence="2">3.1.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_005868</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF99"/>
    <dbReference type="OrthoDB" id="6509975at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016158">
        <property type="term" value="F:inositol hexakisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF43">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024793587" description="3-phytase" evidence="4">
        <location>
            <begin position="18"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8302460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="428" mass="47231" checksum="CE76C4B74791596B" modified="2020-04-22" version="1">MLLDQILLLSLTGVTSSALLPEKQPSSTSTTNVPQYFQTTPELWAGPTATGRAPFLAQTNPVSFAPTVTFVPNSPLETAQPIVGQGHNESIFQLMGHLSPYLPNPSGFGVAEYPLPPGAKIAQLQQNYRKNYDPRSNAQSYDNCPNANNYRSAGGSNATNQWVATYLQDATARFQSMVSPEFNWTVVDTYAAQTMCPYETVAYGYSAFCNLFTYQEWADFEYSIDLYFSGGSSFSSPTGRAVGIGYVQEVVARLQNHTLGYSGSQINTTLDNNTDTFPLNQSIYFDFSHDTNIMSILTAFGFKQFATVLPATHYPGPHNLTVSHMEPFGARLDIEVIKTPKPLAANRTYVDGKETTYIHFILNQRTIPLGFSFPECGADRLDGWCELETFLDVQSKSTKEAQYEYACFGDYPAEPYGSVTNGAPNTYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFA0</accession>
    <name>A0A5N6KFA0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Plastocyanin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_005846</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFA0"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF414">
        <property type="entry name" value="ADR239WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="4">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="3">
        <location>
            <begin position="105"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8302434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="27951" checksum="C8DDE9654FDE2C8C" modified="2020-04-22" version="1">MQYWLIVQNTTLSFDGVARSTINFNGTIPGPQITADWDDNVIVHVTNKLTNNETSIHWHGMRQLNNSHSWYHSHFILQYGGGLFGPLITNGPATGNYDANLGALFLNAWNHVPIQSLWDRAKTGEPPTLLTGLINGTNIHNGVGEKFSTTFTTGLKYRIRLINTAVDGHMQFSTDGHNFTVIVNSFVPIVPYNASSILISTGQRNTNAANITGILRFIGSSITANPKSTATVKASTSCLDKPLTSLIPIASTTANQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFA6</accession>
    <name>A0A5N6KFA6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_005793</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I LYR family. SDHAF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFA6"/>
    <dbReference type="OrthoDB" id="3554803at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20268">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045295">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF1">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="6">
        <location>
            <begin position="9"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="68"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="515"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="717"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="573"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8302367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="863" mass="96027" checksum="4E118F2701CB092D" modified="2020-04-22" version="1">MARLSGLQREVLALYRKCLRESRKKPAEARSHFEAFARVEFDKNISLDKKDFSAIEYLLRKGQRQVDMYSSPEQARRKQRIEARGRRSRISRASTVTRSQRRASKQARQEVFGWESPRSDITRQGHQSGSQLAHSKISIETKTRRSSEIITDSPWIDSVDGACSTLRRVKACVTNKNTKSQAGTRSNSINSRQLTGGPADQLRRYQALPRASTPQSSRIQDSRSLYRKYNPSTHTVFASPAKSRAFLAASTLASLYEEQGNPSRTPESGDPIKKEISRGNTAFIGVPRLASIAQKESFSSSVHSIVQSIASNPSSRSPSQRRALKRFTRELDLYLQIAKQAPTQTPISSVLSTSFSSQTIQTIQEFKPYHAEFQAAGLAVTSAEQRNQSGFKLYERRNTVPEAQPLPYDVRSAGLLAESERQRRRTLSDIEEPKAILSDENMGIKGSNLLIKKPIPDSVNPVTVLSTMNGASEETVIEWAPAYERDSPTNRLESPPCCDLAPPIMRVSSPAKVYPPDSFAPPKHATSPAKKSLPWLRKPQITAESTPKIGNASKDTRLSKLAGDATASPPYSEFTSQPNSQSSSIVLHLNTPPEHKRSIPSLAPKIPASIPSSATPSYPQPFVVPREDDNIGVADFASLEQLPNQTRAKLANGDTIAQKDIRLLKNHATQTSAVPSFITRAPHFTTQIPVTVQSQQRRGLVLKSSAISEYKKRQLPQGAKTISIPKSAPPNQMPPAASTITSSYVPPSPLQCTQCNVELNTLSDSRFRSNVTSTSGPSIGFEPNLKRKNMPQRMFQVSLSNDTCKEMPLYMTMMKEEKWVLVQTVNKKNRIHQRMKDTMLVNLIFAKLQEMLFPNEYQHHTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFE3</accession>
    <name>A0A5N6KFE3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CCT-beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_005895</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFE3"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000002">
        <property type="entry name" value="T-complex protein 1 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012716">
        <property type="entry name" value="Chap_CCT_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02341">
        <property type="entry name" value="chap_CCT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8302496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="42758" checksum="634E518073E3A8B9" modified="2020-04-22" version="1">MLKLSEKIYRVQFAELAVDAVLRMKGSSDLSHIQIIKKAGGKLSDSYLDEGFILDKKIGVNQPKRLEKAKILVANTAMDTDKIKIFGARVKVGSTGKLAELEKAEKDKMKAKVDKIKAHGINCFINRQLIYNWPEQLFSDAGIMSIEHADFDGIERLALVTGGEITSTFDHPDQVKLGHCDLIEEVIIGEDTLIKFSGVAAGQACTIVLRGATEQLLDEAERSLHDALAVLSQTVKEPRTTLGGGCAEMLMAKAVEGAAVKVDGKKQIAVGSFAVALRQLPTILADNAGYDSSDLVARLRSAIYDGMSTYGLDLLTPGGGIADMRELGVIESYKLKKAVVSSASEAAEVTSPQSGQYHSQCPTETRKMSVMKEEKNDDCIMKMQTCSRGFVATIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFE5</accession>
    <name>A0A5N6KFE5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_005825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFE5"/>
    <dbReference type="OrthoDB" id="5398396at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024801976" evidence="2">
        <location>
            <begin position="31"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="320" mass="35259" checksum="13F4F4D5BCDDF985" modified="2020-04-22" version="1">MRVGQLGCEAFVWIVFVSSVLLSLTFSSSSKDVHGCGYRYHFGGISVAGYECKRFQLQTHFLIDQRRTFPCAPSFMIRWLLKPIHLHSVYLELANYHPLSNPSASSHITSMNRKPGSLHCHKSLHIQFACYAIADKSYTPSLILKTPAQYRTIISQSINAKYIDRFKLQVGLTASLYHSEETLFPFTSLTAPNLFPATAPANIPGKFATIKPIAPPLNPPIRLQNFPVGLPLFSAIPSSFNISSNTSPNCSSSNFFSSSAFFAFDENPKLDHGNPPGTADGSGISSSSSMDVEAVEAPDPKPWYIRAASYSLRRDGSERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFE8</accession>
    <name>A0A5N6KFE8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EXS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_005888</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFE8"/>
    <dbReference type="OrthoDB" id="2159384at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF46">
        <property type="entry name" value="PROTEIN ERD1 HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="6">
        <location>
            <begin position="105"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8302484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="339" mass="38881" checksum="1C337B775ECAFB13" modified="2020-04-22" version="1">MDGDPAVENELDSFSRTLPLPYRVALIIVLGVWAWGANLHYLSIVKINVPSLIQYPQRASPRTDPPHHLSAYRLATYLTIPLVLSILLFWTLSHRDPALVIYYDFLPISYICLLFFAFFLPLRHASYSGRFHFLSALKRVSIGGIALPNEGKFGDILLADVLTSYAKILADLDHLLRYAAKSLSKRILNKHHHYNALSTLARKRLHQFSLLLLLGHNQRLGPHPSHPLIKKNTSSYPLRPRLYLPAQELYYIAILLDFLLRFTWSLKLSPHLDHFADFESGIFLLEVLEVARRWMWIFLRVETEWGREKEKGNANGLLGGPGVDDVLLGDYRDDDDYSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHD8</accession>
    <name>A0A5N6KHD8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006308</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8303001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHD8"/>
    <dbReference type="OrthoDB" id="10261782at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="66" mass="7643" checksum="C24BA3A2E32EA371" modified="2020-04-22" version="1">MSSREVPKLLDDQKGLEVRQLREAWVLYGIGIDDLVDIHRFSDLKGDVIVPVPRQEHKTIRSMTQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHD9</accession>
    <name>A0A5N6KHD9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006014</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHD9"/>
    <dbReference type="OrthoDB" id="3531976at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="69" mass="7751" checksum="0A3422642753289D" modified="2020-04-22" version="1">MMAKREAIIMTVAAVGGLIGANALFKPSPHHSIKAGMDSQLHSYNAHTKPHVEQDPRYVFQFRDFVMVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJA7</accession>
    <name>A0A5N6KJA7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJA7"/>
    <dbReference type="OrthoDB" id="3515175at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="120" mass="13995" checksum="D6430E727626CAEE" modified="2020-04-22" version="1">MLDITDFERVRYYFVNFGDDDHHDENEDEDEKTERQVSALSMTPLTEPQYLWGYCKENDPSSQKIFGDLVENFRTFAVDLTTERCIVHGPAVYGWSRRHVVGMVNDSVLGRFLQSPRILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJB1</accession>
    <name>A0A5N6KJB1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJB1"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="83" mass="9794" checksum="4A0D30EF336D288F" modified="2020-04-22" version="1">MRNKLTKSFIHTLILHHQLLLPFSVNNSSKINYLPNYLHLLLATFPLYSFILHYIHQKHLPTNINSTYFPKPVYNTQNKSNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJB2</accession>
    <name>A0A5N6KJB2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJB2"/>
    <dbReference type="OrthoDB" id="1747252at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="99" mass="11171" checksum="38DE2372B2BC96ED" modified="2020-04-22" version="1">MAAPGLRLAQMSRLSLSTARQTLLHTPKASIPIVQVRHKGFKERILSKKEKAGIVNGPTKSFSKKKTTEKKKKKARTTYRQFDPKDAETFTLCDAMRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJB3</accession>
    <name>A0A5N6KJB3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJB3"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="105" mass="12060" checksum="6BF8FC1D4DD7C090" modified="2020-04-22" version="1">MMSEDQRIRDSFSLYSLTGASQGHNMSRPTTPPYTNGNTAEHLNSWSWAGSRDRGPSSLFRDNSGPPTRRGSMAHILNPAETAEREEEHEEEMLREEDRKRKRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJF9</accession>
    <name>A0A5N6KJF9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJF9"/>
    <dbReference type="OrthoDB" id="1867012at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_bL27"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="161" mass="18827" checksum="6067CA87683DDD95" modified="2020-04-22" version="1">MGRDHTIYATQPGYVKYYKDPERHPKRQYIGVVFKRDQVLPLPRNTVRRRRLGMEVAKIVEPETPQVEVEITGLESGDASVLGVKEKKKKRERKGEEGRNLQLRPGYMYREANWEIGRAAERAKVKVRLYKPGDRWTAWRKANVRKAKNAEKRGLAGRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJH0</accession>
    <name>A0A5N6KJH0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">ATP synthase F(0) complex subunit e, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">EYC80_005207</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 15">Subunit e, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the ATP synthase complex composed at least of ATP5F1A/subunit alpha, ATP5F1B/subunit beta, ATP5MC1/subunit c (homooctomer), MT-ATP6/subunit a, MT-ATP8/subunit 8, ATP5ME/subunit e, ATP5MF/subunit f, ATP5MG/subunit g, ATP5MK/subunit k, ATP5MJ/subunit j, ATP5F1C/subunit gamma, ATP5F1D/subunit delta, ATP5F1E/subunit epsilon, ATP5PF/subunit F6, ATP5PB/subunit b, ATP5PD/subunit d, ATP5PO/subunit OSCP. ATP synthase complex consists of a soluble F(1) head domain (subunits alpha(3) and beta(3)) - the catalytic core - and a membrane F(0) domain - the membrane proton channel (subunits c, a, 8, e, f, g, k and j). These two domains are linked by a central stalk (subunits gamma, delta, and epsilon) rotating inside the F1 region and a stationary peripheral stalk (subunits F6, b, d, and OSCP).</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the ATPase e subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJH0"/>
    <dbReference type="OrthoDB" id="2125027at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008386">
        <property type="entry name" value="ATP_synth_F0_esu_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12427">
        <property type="entry name" value="ATP SYNTHASE E CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12427:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT E, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05680">
        <property type="entry name" value="ATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="11 15" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 15" id="KW-0138">CF(0)</keyword>
    <keyword evidence="5 15" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 15" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00057306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00064647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00074682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAB8303835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="93" mass="10158" checksum="3FFCCEAAE4CC63C5" modified="2020-04-22" version="1">MASTGVNVLRWSALGAGVFYGFYHQLSISSAAKAAAANREFEHKQKLIEQARAEYAKKNLPASQKTGGGDIIRDPEDKNFDLEAYLKVLAAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJH6</accession>
    <name>A0A5N6KJH6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJH6"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="224" mass="23803" checksum="55D771F2B2EE93D4" modified="2020-04-22" version="1">MASSVASNGSPTLRRSMNQSQENSGLGADDVADKMTTRMDTANTLKKAATALSTNKLGNQAAPKKMKLSHETYIAPATAATSFPSPTFDSMPNPVDKLLAKLSEQQAVLNRQHEALRNSDDYGPGNSRIIDYNSAPTSVPITPATETFDSGTATTAPTTRPQSRGEGDSQPSAEEVLRLKIELEAAKGRIARMDQELAQNRITKHTIDQAIGSVSEADFPLGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJM5</accession>
    <name>A0A5N6KJM5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_005266</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJM5"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF83">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="65"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8303902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="365" mass="40745" checksum="7B10A1CD3C6C5635" modified="2020-04-22" version="1">MEKSEDDSAAPQTQIHDLTPNTTSRSLPDIGVSKEVRADAHIATEIEHSMTFRDGLRLYPAAVGWSAFFSLGIIMTAFDPQLLGSLYATPAFQRDFGYKYKDGYIISAPWQTALGMGNPIGQVIGALAVGYPMEWYGRKWTYMGCVATTAAFIFVQFFARSLPVLLVGELLGGLVLGTYTTIAPTYASEVCPIALRGHLTSYINLCFVMGQLLANGVIAGTSQLDNHWAYSAPFAIQWLWPIIIMAGTIFAPESPWWLIRKDRLEDAEKALDRLSSKTVNNKLVLAMMIETDRLELEMETGTTYWDVFNKANIRRTEIAIAVFVTQVFSGIYLVGYAAYFFQRKSHRLVVCIYVSRLHAWKVEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLF5</accession>
    <name>A0A5N6KLF5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Actin-related protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLF5"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13395">
        <property type="entry name" value="ASKHA_NBD_Arp4_ACTL6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000375">
        <property type="entry name" value="Actin-related protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000528">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="50075" checksum="D58F8755D231879E" modified="2020-04-22" version="1">MQPTDVYGGDEVSAIVIDPGYSSIRAGFAGEDTPKSFINSHYGVRDGESFYGDNAIHNPSANLEIRNPMNKDGIVEDWDTAEQLWKYAITSRLTSFKQADPRTNGLNDKTEEMEVDMDVDGQERPLEEHPLLMTETAWNTVKSREKAIEVAMESWGSPAFWLARNSVLAAFGGGKATALVVDVGASNASVIAVHDGIILKKSVQRSPLAGNWLSSQIRTLFKTAEPKVELTPHFMISSKTPVDAGAPAQATYRKFTTPPTPSFRALEEERVLTEFKESVVQVWGGPNRLSYTTGPGTTNVDYAKQQPGRVFEMPDGANQMWGIERFNVTEGMWDEKAALPAENEPAPAKAQTLPEMIKASIAAVDMDLRAHLLQNIIVTGGSTLLNGFTDRLNSELSLLYPGARIKLQAAGLTQERRFGAWIGGSILGSLGTFHQMWISKKEYEEFGASIVEKRCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLG0</accession>
    <name>A0A5N6KLG0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_003974</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLG0"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000565">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF464">
        <property type="entry name" value="ABC-TYPE TRANSPORTER CICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="153"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8304596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="414" mass="46060" checksum="D28FEAAAD9C83808" modified="2020-04-22" version="1">MKRFESVFRSNVFAKFSEGLSGTATIRAYGLQNRFITDLRKAIDEMDSAYFLTFSNQRWLSTRLDIIGNLLVFVTGILVVTSRFSVGPSTAGLVLSYILSIVQMIQFTVRQLAEVENGMNATERIHYYGTSLEEEAPLHTIEVRPSWPESGEIIFNNVQMRYRENLPLVLSGLSMHVRGGERIGVVGRTGAGKSSIMSTLFRLVEISGGSITVDGVDISKVGLHDLRSRLAIIPQDPTLFKGTIRSNLDPFGEHSDLELWSALRQSDLVASNSNLEDEVTGRIHLDSIVEDEGLNYSLGQRQLMALARALVRGSQIIVCDEATSSVDMETDEKIQRTIQQGFKGKTLLCIAHRLKTIIGYDRICVMDKGMIAELDEPIKLWDQGGIFRAMCDKSGIRREDFARAAIPTATIMDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLK0</accession>
    <name>A0A5N6KLK0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VPS8-like TPR-like repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLK0"/>
    <dbReference type="OrthoDB" id="289913at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059070">
        <property type="entry name" value="TPR_VPS8_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25066">
        <property type="entry name" value="TPR_VPS8_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS8-like TPR-like repeats" evidence="2">
        <location>
            <begin position="4"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="347" mass="38201" checksum="470CF2A48EF46A9A" modified="2020-04-22" version="1">MNASETVEDLLAALQKYINVGIWLCQRQTPPLSNHITATPDRKRSSGKSELLPEEVLWLDLIDIAVQITRKLSPSLEDTEVSKSNEVDREKFIAQLRTLVQRTFTALLTSTSTPRASGANLSFLRILREFLTKASISSPNLSDLRAVLASVFSAYAYEETILSLANRLLDKDLFVNVQSATSLRQRGWRPRGSTCEGCGRRVWGPGASGDVFSQWEERQKLEEQKRKNKRTTLSGGATDRGKGVIPARSENSPKGGEESSGSGNGKGKGKGNSMGEESAGPRINMNGRPDDNDNNDEAKFRQELGPLVVLACRHIYHRACLEQIQTDDNAGRDGLHDGREFSCPIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLK2</accession>
    <name>A0A5N6KLK2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLK2"/>
    <dbReference type="OrthoDB" id="300641at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024926564" evidence="1">
        <location>
            <begin position="19"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="80" mass="8811" checksum="9AC781DE5B5CD4CA" modified="2020-04-22" version="1">MKLHSLIGLLGLGYLANAVDLRPRNYDSHDYYVLHLDPTANPIQVAGRLGLTHDGGGYCTYSLEGTEETEAVAGRCRYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLK3</accession>
    <name>A0A5N6KLK3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleolar complex protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_003889</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLK3"/>
    <dbReference type="OrthoDB" id="10266662at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030690">
        <property type="term" value="C:Noc1p-Noc2p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030691">
        <property type="term" value="C:Noc2p-Noc3p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005343">
        <property type="entry name" value="Noc2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687">
        <property type="entry name" value="NUCLEOLAR COMPLEX 2 AND RAD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687:SF4">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03715">
        <property type="entry name" value="Noc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="486"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="486"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="518"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8304501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="61220" checksum="3868C7C9C0697C7D" modified="2020-04-22" version="1">MVKKWNKAMTEQKSLRAMRQVVLAFRAAAHVNEDEGKEYKYSISDSDVYHELLLTALKLVPEVLNHHLPVKETAAGKVRVSTDSKKFKTLSPLLRSHITSVQHLLTSLSDASTLKLTLSSVIPLLPYLLSFKKVLKNVVKTVVDIWSDASSTEVTRINAFLVIRRLAIIGDAGLREAVMKTVYQGLLKGSRNTTIHTIQGINLMKNSAAELWGIDQNVGYTTGFTFIRQLAIHLRSSITNNQKESYKQVYNWQYVHSLDFWSTVLAEHCNSLKEAETGKESQLRPLIYPTVQVTLGAMRLIPTSTYFPLRFHLIRSLLRLSRATGTYIPLASVLLEVLNSAEMKKPPKPSTQKFFDFTSNYKAQKSYLRTRIYQDGVGEQVAELLAEFFVLWSTSIALPELTLPVVVMLKRWLKDASNKSSGNKNSKVNSMFVLLVQKLEANSKWIEGKRAKVEFAPNDRAGVDGFLKGFEWEKTPLGAFVVGQRKQREEKARMLEEGRREEDRKRKLEREQEKEIGGSDDDSAAGSDEEEDSEAGFEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLK5</accession>
    <name>A0A5N6KLK5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLK5"/>
    <dbReference type="OrthoDB" id="5387389at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052635">
        <property type="entry name" value="Sec_Metab_Biosynth_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39607:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39607">
        <property type="entry name" value="XANTHOCILLIN BIOSYNTHESIS CLUSTER TRANSCRIPTION FACTOR XANC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="121" mass="13205" checksum="7AEE278C3DFEDDCF" modified="2020-04-22" version="1">MIGDKAKADKERQDRDDENRAHAGHSYHTADPNDVYYDNADAGGSPWGSVSMKHVVSKGRAREDASRHGSRPDDEASYYENPNPAYEGEAYYGGEMVSYEDDQAYYDYGSAAGSGSGTSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLL2</accession>
    <name>A0A5N6KLL2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_004017</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLL2"/>
    <dbReference type="OrthoDB" id="5390143at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024905141" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="17"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8304646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="45950" checksum="E53EA4656352D2EA" modified="2020-04-22" version="1">MYFVLWWFFYADMVLAISSSRPSPGEFINPSAESTQNPLWVIGSEQLLSWETSLRNYTIALWNLNSDGNGYSKGPALLESYDGSDTSLNWTVQTYDFSISASPVFYLLLQPGTLSNNGNSSIPTTQSIASHTFNITSSTTNTEGDKKDHKLALILALSLTIPFVLICIALAIYFVRSRRRRALEIPPHYQYPYHVGFRHRPNRFFATSNSPNTFAFPAQDSSRERQRQSSNTALYFPPPPTTPKSPLSFASSLKTLRGLKGNTMSPGQNKNPNQQFSPTYPSSNPRSPDGYNQPSHLSPTYYPLQRVPSLTSSEAGNPHIQQLREAQEELAIERQRQASRMGYQSPEISPYNEPRGGLNHGDQKWVIRPYVPPDIPVATKKKYYDEQAEARVGRRKYDYDEPEELW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLM1</accession>
    <name>A0A5N6KLM1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003922</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLM1"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8304537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="77" mass="8709" checksum="DDC01C935401DAD9" modified="2020-04-22" version="1">MVSSIIGDLVKVVLNACKAELGGASAKVMKKNIQYWNFEKKFDKYKKKSIASYISARIMNLHEKGSRCPFSDFHPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLM2</accession>
    <name>A0A5N6KLM2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_004081</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLM2"/>
    <dbReference type="OrthoDB" id="298012at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050857">
        <property type="entry name" value="D-2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42789">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42789:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="4">
        <location>
            <begin position="30"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8304724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="289" mass="31455" checksum="7441C40C7FD6871D" modified="2020-04-22" version="1">MEAAKKLGVIVTGTSGKPKRGPDSTTQHTIALILGIARNVAWDDKVVKEGGWQTTLATGLSEKTLGTVGLGKLGTSVAKIMHLAFGMKIIAWSSNLTQEAADQQARDNGLATEDEDGEKIFRVVSKEELFSTADVVSVHLVLGDRSRGIIGEKDLDLMKKTALFVNTSRGPLVQQDALLSALQKGKIRGAALDVFDLEPLPEDSQWRSIKWGEEGRSQVLLSPHMGYGEEASCSAGTDTFVLESLVRYDTRRGKRCCREMHHVTSRKLYELAVIASTSSSRTIIWSSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLM8</accession>
    <name>A0A5N6KLM8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-xylulose reductase</fullName>
            <ecNumber evidence="9">1.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Xylitol dehydrogenase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_004065</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Carbohydrate degradation; L-arabinose degradation via L-arabinitol; D-xylulose 5-phosphate from L-arabinose (fungal route): step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.9" evidence="9"/>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLM8"/>
    <dbReference type="OrthoDB" id="3941538at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046526">
        <property type="term" value="F:D-xylulose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006062">
        <property type="term" value="P:sorbitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000068">
        <property type="entry name" value="Sorbitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF9">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="12">
        <location>
            <begin position="19"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8304703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="358" mass="37895" checksum="BBB7387D16103C27" modified="2020-04-22" version="1">MADISGKSNKSFVLEKPFSVKFEERPVPKLESEHDVLIAINYTGICGSDVHYWVEGAIGPYVVKDPMVLGHESAGTIVSVGSAVKTLKVGDRIALEPGYPCRRCPACLSGHYNLCPEMHFAATPPIDGTLAGFYTSPADFCYKLPENVSLQEGALIEPLAVAVHICKQAVITPGQSVVVMGAGPVGLLCMAVARAYGASTIVATDIQPARLDFAKSFAATHVFTPQRVSAAENASNLKSEVGLPDGADVVIDASGAEPSIQAAINVTRRGGTYVQGGMGKADINFPIMELCTKEITAKGSFRYGSGDYSLAVELVRTGKVDVKKLITGEVQFEDAEEAFKSVKEGKGIKVLIKGPNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLP4</accession>
    <name>A0A5N6KLP4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_004107</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLP4"/>
    <dbReference type="OrthoDB" id="2341546at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000003">
        <property type="entry name" value="C6 transcription factor (Leu3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF21">
        <property type="entry name" value="REGULATORY PROTEIN LEU3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="504"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="10">
        <location>
            <begin position="64"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="625"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="632"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8304754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="727" mass="81552" checksum="FDF9524BF56334E7" modified="2020-04-22" version="1">MEPSNGIIGGAASSSPTTGARPGTGSVLSKRKRSGTGFDSSPGTANEQEDEDSEKRKQPGVKRACNECRQQKLRCDVIQEPFTTCSRCLRLKLDCKIESNFKRVGKRSKHAEMEKQIERLQRVVAQAQQAGFIIDEEEDLQSPIANSVHQHSRNQSYIGSEEAVSSLLHLKQGGSYNTQYARQIENVGLTGDAINHLFNEFFSWYHPYLPFLSPEQTPDQYFQQDPLLFWVIITVAARRYSADPNLLTSLHGPVTRLLWSKVGEVPNNYHIVKAMILLCTWPLPISTTSSDITHILCGVMMKAATGIGLHRPNNTQDFSRVSVDLNREQLHDRVVTWAVCNIVAQSTATGYGQPASTLYDWSLAIRPGEEGPFTLSPELSSRLTIERFCDKVSKEMYNNANDPRGVAGEESRAQLTRVYRREYEEIRVAILSRQNLSPIVDLHLRAAGLHLRLSAFFDSSTTHGYLDDLMGLWRATAQFLDLVFELETPADNVTGGILKYATGYILQMIIAACFSLLKLLSSFFAKFMDFDRGRQLFHRTISAIRTMSVVNNDLPWRLAELMVQMYNGARVEQRQMAHMNNGNELDSNCVVIDDSLQLKVRCRMSMSLVFDSIWRWREEFQTQGRSIEAMRNPTNPDSANESSDSSTHLDSTLVPASHQMQNQLLAPVDTITPNEAITGANNMLGGNTSYGETNYEVFDPLNWMLDGLVDFPYSYNAVQGLEANGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLQ7</accession>
    <name>A0A5N6KLQ7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ino eighty subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLQ7"/>
    <dbReference type="OrthoDB" id="5413003at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038014">
        <property type="entry name" value="Ies1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37287">
        <property type="entry name" value="INO EIGHTY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37287:SF1">
        <property type="entry name" value="INO EIGHTY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="630"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="682" mass="76566" checksum="6293E723FDFEDCC8" modified="2020-04-22" version="1">MADSLGAVTVASDKADVLPPTKDASSSSSINATRNTESPQTTPPTISTKPANDIIIEDEDRGTPVGENSTNTPGGNTSRARKSGKDKDQPITMQGNIGPQNNKIRHLKKDDGEPLWRKDIQYDFLKLIFEDDNEVFTNSYDDTLPKQTFADLYIDAMARSSKTSKILRDKLMSEHEPAKNMAMVCLLVNLGRMNTTLNFFPEMRAQLRTYHAIPSLQARQDPNSYKQLQDAPRLKSILKGASEDRPEPSSLEKIKKTLIPRTNPVNLIFVLATYASKITELHFPKNREFFDLIMNTQITSKSRSKAFLWLMWFYLESDFTEEGADENPFGAGVDYQTNVRNQGVPRLVDMSEEEEALENVDTEEELAFGQSKMRDRKRIIEADQIQFQAEQGPPKRGPKPKLNLPLDDGSNSSAIMSRIRPRYDDVIGTSGGLISSRYRGGKNGEGSSPAPEIPATLTRRHRPLTAHQIAVERNRNQRVDYILVRGLRKEHRRARRLRKQEGAFSRAVKRTKAMVDAFSDSEDDSYHRNPYPFRERGFGGLIQLEDEEDDYGEEVSAYAAAFRRVGRRLNRWDDQKGLNLGVVGTNRVSTSNGINGHHSRDSDETEDDRDQTPIHHSKHQANGHASVQEAGDDDLDEMDKELLGLVSDDDDDDDLDMMEKSLLGIGGDETEADASDAGMDMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM16</accession>
    <name>A0A5N6KM16_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM16"/>
    <dbReference type="OrthoDB" id="3946221at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="512"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="546"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="623"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="772" mass="85065" checksum="BCCF303BE5052C85" modified="2020-04-22" version="1">MTQTPEIIFSSPTLPPPIQPSRQPSERPESSNTNASSPAEKAGRILQDIVIPSSLPRSRSESLASPFKSPAMGRRSSSSIYPDTNVNGSMPNEQPPTSLAKFDPSGDSVSQHSRRRSWSRPILDEDPFAGNGVTQKRSSTDKSQSLTLELPSSRRMSVSLNAAIIPQHESSRTSNCKNTQPEETSRNGASEKAVPLTLSKEKKDADAKGSSSSLNKKWIAERAAVSKRISAAKSSEVMVLSSDDDDDDDNEDDKYDSKVPVSEEKQETRPEAQNVNHEGYINNKDEENYEDDESFGLLLETLDASNQEDQLHSDRSDNVERPRRAKIPSPWGTNSKHLVYSDDLASLSPNRDAKAPSVEESSPKSVSKELNVQNNSQTDLQTDGDETLDLSQWQIPQKQNFQPKIRSISSTRHDISALLRSPLGGLPTLSNRERGPVTEGDSSKEVPIPQKSYRKPPQNDSSGDTEKETSSFAPIPQKMDFQPRVRKTGDAPQPAPFSQPKTLSIFGKLGASRTSLPTPDTSSSSLVGTLTNTSPSRSNKLKPQPLQQDTLQNSSSQLSTSTTSAPINTKENREIENPKPKWTEHRLEAPIPPSPTKSILRSPQRSIDPPSQPSPSKNVVFASSSPQPSSPLTPQLSPTHWTRDHWLLLDSILQTWKPENQNDKDLDVNTTNESSKYGRRNSTRVISRLLGKTVNLKDKGVGIGDGGVRVFKNGSGKRGDDIGNERLRLEQWHLEAVDEFRGEVPGWDEAVVAKRVFALLVGEERRRRGIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KM19</accession>
    <name>A0A5N6KM19_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_004213</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KM19"/>
    <dbReference type="OrthoDB" id="5550281at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF5">
        <property type="entry name" value="BOX PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="90"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="90"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="196"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8304884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="318" mass="34109" checksum="38E3F300B2855E02" modified="2020-04-22" version="1">MWSKFIGGLATLQEAIQSVSSAYIKHTNAVLGEHGAGYDIDTALSKLGENPLLGSLGALQRAATPVVVKAVDQAPEKKERKKRQHDPNAPKRPLTPFFLYMQTARPIIAKDLGNVPKGEVSSEGTKRWTDMAPKDKALWQDAYKDNLRLYNARMHSYRKGNLTAKEMSDDAAAAYADENNIGADASADAQLVGEASAGVTATVEEEEDAEGEPEAEAEAEAEAEAEVEKTPTPEPAPKTPKAKGRKSKGKSDVAEDIPPPSSASIVPPQKEASPARKRKRSGKKAADEPVASTEQEEATIETPKSAPKSRKKKTKTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KNU9</accession>
    <name>A0A5N6KNU9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KNU9"/>
    <dbReference type="OrthoDB" id="5280838at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="147" mass="16680" checksum="4A984FD6264A0963" modified="2020-04-22" version="1">MAGGKYITASYPSSAHSSNPETYGWCASYASFARVVFNGHSTSTASSSIDRFAKSTNRHDAVRTSRLMSWDDERRDEMRLDEIFLSPFSLPFLYILFFCTLFYDDDDDDDDDDDDDDDDWIGWDGMGWDRREGSGVLASVFGLLLCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JMI6</accession>
    <name>A0A5N6JMI6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome c oxidase assembly protein CtaG/Cox11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_010219</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000025">
        <property type="protein sequence ID" value="KAB8288216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JMI6"/>
    <dbReference type="OrthoDB" id="1704689at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.370.10:FF:000001">
        <property type="entry name" value="COX11 cytochrome c oxidase assembly homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.370.10">
        <property type="entry name" value="Ctag/Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00155">
        <property type="entry name" value="CtaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023471">
        <property type="entry name" value="CtaG/Cox11_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007533">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_CtaG"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003465">
        <property type="entry name" value="PRK05089.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21320:SF3">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21320">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04442">
        <property type="entry name" value="CtaG_Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110111">
        <property type="entry name" value="Ctag/Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="205"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="206"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8288216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="26382" checksum="DB308111E7A9EE4E" modified="2020-04-22" version="1">MEQLRAPFSQKNSSTMYYTLSIILGTVAFSYGSVPMYKMICQTTGWGGQPIKAPGHGGGAAGEDPSERLRPVTSAKRIRVTFNGSVSDVLPWKFTPQQREVRVLPGETALAFYTATNKSDEDIIGVATYSVTPGQVAPYFSKIQCFCFEEQRLNAGETVDMPVFFYIDPDFVNDPNMKGIEQVTLSYTFFKARYDKNGHLKPMPAGISSSSSSSISSGFGSGSPSSSSSSSSSIVRSPVSHIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JP24</accession>
    <name>A0A5N6JP24_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_010674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000022">
        <property type="protein sequence ID" value="KAB8289514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JP24"/>
    <dbReference type="OrthoDB" id="4739136at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8289514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="657" mass="73769" checksum="72D996E2CC8722F9" modified="2020-04-22" version="1">MYPNKIATFESHAAAAWNTESEIGDAEEVPTSANIVTTTNRVGMSATLVPRGLFRTNQTIRGRSNGGRGRGGGNRGVVRGRGIDSGVQGRGRRADRNGGRNGSYRSGRGTRGDLSGNASRGGHHAVPTGRGNGRSVESTPRGGCFRDGTGLRAAVPSVNHRADSESLCRPVVRARELGVNLSTGWAEPTRLLTDAHKEQLKFEAALCSNTKRFLQEPLDGEVFSAIGFYQWQLKEDNPQDLFRPQLKDLDHLKTTWRVYIDWNEAHNWFRIRAPSPAGQTEIIEVIRGIRHAVDSAHARAIMAATVYVVVPARYSINSTLLVALSDQFPRSDGAKHVYDIRFSKHSSDDELKNQIVSCSSKMEASVKEFRANLSKSLNELKHLKDWMQMQFRGLHEDDEAVDPQVVVYMMNKVRLNSDKFMVWSTLDYKLSEVKPRHVAVFIVQNSSGDMYQIEADIDKAHGGYQCGAVKVIEEDRRDKCMEIVTVDIEKVDWNIEIISETAGTIIDSSFQDLVESCLQPFVRTGLKAQLLEERQDKYNFTYPKIAPRSQPGLRVDKVTLQSIYRFKTITGGYCLEFTINRDWIGLNTVDEPEVSAGITMFHDQWDTEMESNEYSTADRDWQEDMSNFFPNGGFKVFVEQLNYLLYGFQKSKSLGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JQT2</accession>
    <name>A0A5N6JQT2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PSP1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_011155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000018">
        <property type="protein sequence ID" value="KAB8290290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JQT2"/>
    <dbReference type="OrthoDB" id="243127at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047767">
        <property type="entry name" value="PSP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007557">
        <property type="entry name" value="PSP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43830">
        <property type="entry name" value="PROTEIN PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43830:SF3">
        <property type="entry name" value="PROTEIN PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04468">
        <property type="entry name" value="PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51411">
        <property type="entry name" value="PSP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP1 C-terminal" evidence="2">
        <location>
            <begin position="613"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="819"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8290290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="860" mass="93233" checksum="A59EFC5198AA941F" modified="2020-04-22" version="1">MTSSNPSLLLGKFNERRSTPDSEALASSDDEPDRQEAQQPVNPPQKPTRRASWLNDTTQSGTQPRKGSFASSTMSPTASHPSTPSAESNAWGPHAQAAAGRGHTSSSSFPWSSGIWNSESRKEPPSRLTEVLPSPTSLHPPGSAGNGYFPNEMMNQRDPSVNPTIPFAIPLHPTPKTYRSQSYSVGQLDPDTSAGPSPAAVPATSGRGRGIGHSALQHRPSRPSMLSEMTEGGLGKVKEVEDDDDESTNSSSHGVQIQSQEAKTIELLARENAMLRQQQYQNLRLRPRSSTSNAFGLGNGYGLQEEPLPEESDYAIDELDELNDLQDTSKAMLGRRMSEYGIGGSQRASPYTLENRKLENVKKAYWQSSLGFGGLSDIPQSRRHSFADVPARQGSVSSIAGDPLSQLEASIQQSLSPKDHADRYNEGNGYSTNDHATYFGNLTQTGRNSDAFTPTAFNSSAYPYGSVNQFSSGRPVSPHRSMYGVPQPRHNQLLYIVLFKCSRADVFYVQEGTGLSVKPGDLVIVEADRGTDLGTVAKDNVDWATAKELKEHYAEEHYKWLMMYSQGAVGNTDGTGAGLMAAANGMQGSAVGGMGPPSQHGMQEPNPGEIKPKIIKRLAQNHEIQALRDKEGNEAKAKRVCTQKVKEHGLHMEILDAEFQMDWKKLTFYYFADAYINFNSLVTDLFKVYKTRIWMSAINPASFASPALGLQAPSGIGPGAVGVNRTTQSERRPQQAEQPQTYNAAQASRNYQGVFAQPFQPTLDRSSAAAPGFQPQGYTYGYSPFGSTRNVGTSSAYVPSMIDPYAGFANTTDYQTPGRFPSPHGTTPTHDGSEYGRQGGLVGQSDGWIGAFQGLSMGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JR67</accession>
    <name>A0A5N6JR67_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Luciferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JR67"/>
    <dbReference type="OrthoDB" id="9987011at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048273">
        <property type="entry name" value="Luciferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040841">
        <property type="entry name" value="Luciferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695:SF1">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17648">
        <property type="entry name" value="Luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8291262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="102" mass="11196" checksum="46685F37B7833344" modified="2020-04-22" version="1">MNLHPDDAKDILEKGWGERHPMAGASTPRAISNFLSCLPSSLSAWLSPRVVPEQFVLIYAPRDKDELQVVCHIIEAAAFWVSGEQFTLPIEGIPLADEPVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JR72</accession>
    <name>A0A5N6JR72_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000016">
        <property type="protein sequence ID" value="KAB8290906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JR72"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8290906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="159" mass="17848" checksum="9D652668ECC946F8" modified="2020-04-22" version="1">MSSNTPSAPNCEGGRGNSASTNGGSQMVQDNSPNKTHEGPCLLCMRAAVQGDHLDLCNYQASIGEACSRCVERDLPCCLVPDWIKKLWDNYTLWKLSERTSTGLSMKDEEWTLTEKTGERLKHNDHHRVGHARLARSRKNRTVGFDCGVLFPYYPQIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSS5</accession>
    <name>A0A5N6JSS5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_007866</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSS5"/>
    <dbReference type="OrthoDB" id="10264446at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051754">
        <property type="term" value="P:meiotic sister chromatid cohesion, centromeric"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901991">
        <property type="term" value="P:negative regulation of mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098813">
        <property type="term" value="P:nuclear chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000016">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002554">
        <property type="entry name" value="PP2A_B56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01603">
        <property type="entry name" value="B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028043">
        <property type="entry name" value="PP2A_B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="686"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="687"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00064351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR028043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8292123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="709" mass="79575" checksum="EE0358B7DF91A434" modified="2020-04-22" version="1">MKGFRQRVHEQLSRTKDPNKSKSKKGESKDGTSSPSQSNSREAGQSPAVTPSSSSTTLNDLRNKPLPPNDGTSSSAGPTAQPPLNPALNTMSASDRFNTGGGSPSPATPNRHGALPPSVVISPSAPHIPPPGSAETMPHDLAPPKAGQKSLMFDRLQTTPKDVPEGIRTPKRQHSSRFDISPLRELEKLPGFHEVPPNRRQDLFMQKIDQCNVIFDFNDASADMKSKEIKRLALHELLDYVANNRQVITEAMYPKVVEMFSKNLFRPIPPPMNPQGEAFDPEEDEPVLEVAWPHIQVVYEFFLRFIESQDFNTNIAKAFIDHSFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLNLRSYIRRSINNVFFQFVYETERFNGIAELLEILGSIINGFALPLKEEHKLFLTRVLIPLHKVKSLSMYHPQLAYCIVQFLEKDAALTEEVVLGLLRYWPKVNSTKEVMFLNEVEDIFEVMDPAEFAKVQEPLFHQLAKSVASPHFQVAERALYFWNNEYFCNLVSDNVEIILPIMFAPLYENSKGHWNRTIHGMVYNAMKLFMEINPQLFDDCSHDYTEHQNNAEAREKARENKWKALVEQAGRSKANGSILPTGPASPSRIKVTPLSADDIDPIAEDNQKRLDSIFQKPAMIVNGLVSDLDVDVDAQRSVSGSSTQAVLGIVSSSAVASKDLDGDPETGDHSFIDDQASLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSY1</accession>
    <name>A0A5N6JSY1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="9">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_010059</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="9"/>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSY1"/>
    <dbReference type="OrthoDB" id="15567at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031405">
        <property type="term" value="F:lipoic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000013">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000007">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050743">
        <property type="entry name" value="2-oxoacid_DH_E2_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178:SF5">
        <property type="entry name" value="LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 9" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="11">
        <location>
            <begin position="42"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="12">
        <location>
            <begin position="178"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="127"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8291381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="462" mass="50637" checksum="FD609ED3D37A69E0" modified="2020-04-22" version="1">MRRQFYSRLFSRQWNLYQSLNLPKQSPTAHKFFHATAKRLAIKPFMLADIGEGIKECEIIQWFVEPEARVEEWDKLCEVQSDKASVEITSRFSGVIKKLHYDAGDMAQVGKPLLDIDIQGGDLDDIGRSNLDGESKTNPVDKSRTDYKVDVPGASQPAAETGTSTTSILTPKGKHAGLATPAVRHLTKELDVNILDVTGTGKDGRVLKDDVYQFAKQRDAALSISQEPLSAVDSEPQKEYVTSLTPVQQQMFKTMTRLSQVRDRINKQLASSPVNGVAKLSYLPFIVKAVSLTLNHYPILNARLDVDPNSQKPILKMRPQHNIGIAMDTPAGLLVPVLKHAQTTSTLLSIAQSLTALQSLATTSTLTSSHLSGGTITISNIGNIGGTYLSPIIVDSQLAILGIGKLRTIPAFDAHGNVISKQVVNFSWSADHRVIDGATMARASEMVRGYIEDPETMLLHMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JT59</accession>
    <name>A0A5N6JT59_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal eL28/Mak16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_006594</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JT59"/>
    <dbReference type="OrthoDB" id="338850at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002672">
        <property type="entry name" value="Ribosomal_eL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10544">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="5">
        <location>
            <begin position="4"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="61"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8291805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="92" mass="9675" checksum="CF61740E68194871" modified="2020-04-22" version="1">MNAEKGVTLITKKTSASQKPAVALNKTTFSKSGRKTFAGVAKTVAKNGYRSDLRAEAVARSSAILQSQTPKKDAPAPKLRGSKAAKAAEKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUW4</accession>
    <name>A0A5N6JUW4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUW4"/>
    <dbReference type="OrthoDB" id="153872at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8292417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="155" mass="16465" checksum="D0599409304A40F3" modified="2020-04-22" version="1">MNVDAHASGDEMGGDLEADLAAEMEAELEAGAGFEDIAATPMSMSGMAATPSVIQGDTPAANEEDDSGDESIEDGESGDDGSEADEVDEDEKARLAQLQEAKEDIVDLEKQIEGLQAQLAAQNNPILRRRIEDKSRKLKAELEIKKSSIGEAEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUY2</accession>
    <name>A0A5N6JUY2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUY2"/>
    <dbReference type="OrthoDB" id="1708389at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021709">
        <property type="entry name" value="DUF3292"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38694">
        <property type="entry name" value="CONSERVED EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38694:SF1">
        <property type="entry name" value="PEROXIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11696">
        <property type="entry name" value="DUF3292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8292447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="478" mass="52339" checksum="A9CAAE87B8DBB32A" modified="2020-04-22" version="1">MDFHDIPSLNDPHAVPTDPYRGRAQPIHNLPIKVEAHEEDIPTDSHALAIADHDEKGAAQVGHGNVEVRDLGWSDESHEVLTPLVGGLPNEALWTLVRRFNKQMYHVKSLPEPPLGGLDLNIADEEEFSPDKLRANIERLYMTVVVGLVNFWKHIARLRSWRERDRTVVFASVYFLAWLIDFLVPTIIGFVIVLIAWPPSREYCFPPAPPALIDSTTGGIKKPTAGVLGNDTSLTGAPEKYQGEAVEQEASNFVNSFTSIAISSAAGKHPQGDPHGDKAGASTLEDATPDPTQMAVSAADAKDSSAGDQTNSLHDKTKEPMSAAMWSKTRPVMHAIADISDGWERFANALSPTPPFPQETPRLKLAACLAPLLLISMFTSSYMFMKMNGFFVGFGFFGDPLIWRGLTYLNREFPHWQKLLEIRNTLLKGVPTNAQLTITLLRIGEANKAPIPPPPSSSLPPPDAAHATAGEDLDHLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUY5</accession>
    <name>A0A5N6JUY5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">SP-RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_006606</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PIAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUY5"/>
    <dbReference type="OrthoDB" id="28127at2759"/>
    <dbReference type="UniPathway" id="UPA00886"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16792">
        <property type="entry name" value="SP-RING_Siz-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.780:FF:000003">
        <property type="entry name" value="MIZ zinc finger protein, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.780">
        <property type="entry name" value="PINIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023321">
        <property type="entry name" value="PINIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038654">
        <property type="entry name" value="PINIT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031141">
        <property type="entry name" value="SIZ1/2_SP-RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14324">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02891">
        <property type="entry name" value="zf-MIZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51466">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PINIT" evidence="11">
        <location>
            <begin position="164"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="SP-RING-type" evidence="10">
        <location>
            <begin position="344"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="442"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="447"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="476"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8291821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="564" mass="62226" checksum="FCD91F970C7D302A" modified="2020-04-22" version="1">MIFREPHSYSGWNKFTRFNYYLLTTTTYLLCNKVTRNPKAKSGGETRGLSIHIVIILVQYPRIKPYVRKVKTGGMLNQTLKNICAAEDMKLNGVKAELQSRIVDRIRLYANSQNSVRFNRLGAIIERPETVSTGMNPYAYQSSASPAANSLPSGAHNYNTPGPAMQSYNRPNGYGMKLEFKTSPFYNMLDQIGEIKNCEAMTQHRHTVSIPIKAHSHPTLSKVANDPTLKIMIFCAGDGNGRQDIAFPHQSEIKVNGGDIKANLRGLKNKPGSTRPVDITKELRLKVPGYQNTVEMTYALTTKKFYLVLYVVKTVPVTELVRRLEYGKKITKESVVNDMVNKSRDADIVATASVLSLKCPLSTLRIDLPCRSISCRHNQCFDATSYLQLQEQGPTWLCPICNNPAPFETLAVDEYVKNILQSTSRSVDQVTVEPEGQWKLYSKPDAISSQPGVASSDFSDDDDLIELSPGGRKASTPITRIGASNGTGTQAPSTRDSLSAAPSNRSNPVGSSLGGKRPISEVIDLTSSGDEEEPATRPPKRQYTSGPPVLNGAAPTFRPKFQNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JV84</accession>
    <name>A0A5N6JV84_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">6-phosphogluconate dehydrogenase NADP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_008184</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JV84"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF3">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G11600)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="5">
        <location>
            <begin position="4"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="6">
        <location>
            <begin position="173"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8292466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="32470" checksum="48C398E73F75B3CF" modified="2020-04-22" version="1">MAPQVAWIGLGNMGRGMCKNLVEKGQLDKSLIIFNRTTKRAEDLSKSLPSGKSTVYTSIADAVSKSDIIFTCVGDDAAINETIDAAVKNGASGKLFVDCSTVHPDTTEELAKKIGAAGGEFVACPVFGAPQMADSGQLVCVLAGPRESVEKVKPYTKGVIGRAIIDFGGQPVGKATLLKVIGNTFILNMVESLSEGHVLAEKSGLGNDNLHQFIETMFPGPYSAYSNRMLSGDYHKREEPLFAVDLARKDARHAMALAKSAGTRLKDVEVADAHLEKVKNHKGEAGDIASIYGAVRQEAGLKFEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JV89</accession>
    <name>A0A5N6JV89_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JV89"/>
    <dbReference type="OrthoDB" id="5414836at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024960956" evidence="1">
        <location>
            <begin position="21"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8292476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="85" mass="8854" checksum="1102E2F524250C8E" modified="2020-04-22" version="1">MVSKYRIGVLIAGLIGVSQGQYLNTTTAIAAPLTPEGHGHQPTCEPKTVTITAPGGGYGSCPTKTVTEILISVSTTTCYERTTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JV94</accession>
    <name>A0A5N6JV94_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JV94"/>
    <dbReference type="OrthoDB" id="4207123at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8292486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="82" mass="9577" checksum="54CACB1AB1EDB4C8" modified="2020-04-22" version="1">MPKDTMESPSLQRIFLLLPEDLPTTYGNKEKPRKNYKSRGHPKFNHNTKNHKRQSSSMNTLQHSKTCGTTISRLKIIRKLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXC8</accession>
    <name>A0A5N6JXC8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lariat debranching enzyme C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_009291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXC8"/>
    <dbReference type="OrthoDB" id="407609at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008419">
        <property type="term" value="F:RNA lariat debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007708">
        <property type="entry name" value="DBR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849:SF0">
        <property type="entry name" value="LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849">
        <property type="entry name" value="RNA LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05011">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01124">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lariat debranching enzyme C-terminal" evidence="2">
        <location>
            <begin position="344"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8293809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="593" mass="66372" checksum="149971B526F21769" modified="2020-04-22" version="1">MASSIQEVNGLRIAVEGCGHGTLNAIYASIEKACEARSWDGVDLLIIGGDFQYGMQMISHGLKKAPYLTIFVGGNHEASSHLWELYYGGWVAPNIYYMGAANVVRLGGVRIAGMSGIWKGYNYNKSHYERLPYNQDDVKSIYHVREYNIRKLLQVGTQIDIGISHDWPRAIEKYGDMKKLWKMKPDFERESNDGTLGNLAASYVMDRLRPPYWFAAHLHCKFSAVKTYEDSQKQKEHEQPKEEVKATELAPPVGRNDVAAENQPIIPHNDDEIDLDMDDDDSPPIEEAAKVATALTDNSQSENAPAEDESAHSAVPSDIRAQLPAAFSKSAPPAHREPRVQPGQPPPPEITNKAVRFLALDKCLPSRKYLQLLEIQPYKSTEETMPATPRAIPRFEYDPEWLAITRVFNPELVLGDKTSRFSEDLGEAHYKALIEKEQAWVDEHIVQQNKLEIPGNFVITAPPFAEGMPEIVNEGPVEYNNPQMQQFCDLLGMENKFYASDEEKQVRMQNGPAPVEERKDGGFGGRGGEEGVGEVVEEGLEADVDVEIEGVVVEEGVEAEEEVAGNDSLLQKFYMIRYPTCFTTSQIAVQRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZB5</accession>
    <name>A0A5N6JZB5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Anaphase-promoting complex subunit 4 WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_006846</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8294886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZB5"/>
    <dbReference type="OrthoDB" id="6252103at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052779">
        <property type="entry name" value="WDR62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45589">
        <property type="entry name" value="WD REPEAT DOMAIN 62, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45589:SF1">
        <property type="entry name" value="WD REPEAT DOMAIN 62, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="751"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="794"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="835"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="925"/>
            <end position="934"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8294886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="960" mass="102957" checksum="2532E7E7935FB050" modified="2020-04-22" version="1">MASTPINSRTYVASTSLGLKSSPAGFPRTPRPSNKNRNPYELGLSLKKIIGTTVSSPPCFDCLSTSRIFAYTAGAAVVVVDIDEDGKHSQRFFRASPTAVAANAGNTAIGGPSTPASNSNDGRNGKGFRDAAIPYAPSTAHTSLESGDSSRTWSSRERIKAATCVSISADGRFLAVGETGYAPRVLIFSLQENSSDSPLAILTEHYYGVAAVAFSPDGRYLASLGNVNDGFLHVWSINQKNGTAKLHSSNKCTSFVKQMLWLGGNVVTVGTRHIKVWRVEDGRCPSPKQKFALDGTPLPLPVQQALKTLTGRNCLLGPLVDATFTCVASLHDHRAIVCSEKGDVCLLDSTEGQKLLKVLSTGFPVTCVAVEMETRQVRIGGRNGKVKTVSLDALLTPSTPPLSPISIDECNEEVDAGHLCAMGYAGGNFVTIDSRHTIEIWGKDDEDADHGFQNTLQPAHGDAVMGVQLLPENNQMGAAFLTWSVNGSLAFWDLHGNSKGSITIGIDHVSMEEEASNSCQVVRISKQALFLVSGDKYGILKILDPSTGACTFEARAHSTEIQDIAIYEDETTTMVASCSRDRTIQLFRRVLYKWELVQTLDEHTAGVCGLFFAENGEKLISCGMDRTIHIRQIVKKDAGEGDVLAAVPVRIITLKAAPVSMTPCFGAQVGNLVVSLLDRTVATYEIASGRLLNSFQATSYDGTDAVTLDSLAMGKPSTLCGKPSTILAGVSTTDKSVRIYDWSSGSFLDREWGHTTSVSGVALLENINLSSRVLISTGLDGTIMMWDIASNATDLQNPSETNDGTRDEGSPKEPTTSRQPMRKVLPKAELAEFQRASPTAPPSGRSSPPRVVRRKTSKLGMANQNPTLSIPSAPAVPSKHFASASDDTGRRNTTRNRSRSPGSPQTRELRRPSTATVDARGRGKSSSSGMSEFASLSMATEQACRTLRAYRRKLLSTEIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZF6</accession>
    <name>A0A5N6JZF6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">EYC80_006880</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8294924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZF6"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052851">
        <property type="term" value="F:ferric-chelate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000067">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF23">
        <property type="entry name" value="FERRIC-CHELATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="15">
        <location>
            <begin position="154"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="412"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="482"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="536"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="440"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="539"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAB8294924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="647" mass="72954" checksum="1017A4198E913C93" modified="2020-04-22" version="1">MTPWLIATAMKSNLISWITGIGHDRLGVFHRWGGYLCLFLALVHTIPYFVQPVWDDGGMLVFGKLFPASRGIIYGTGVACLAPLGWLVIGSLPIVRSLAYELFVVLHIPAAVVYVAMLFWHTNNYLTSWSYLYATVVIWALAYLTRVGNLNWTKPWRNSFLVGDEAAITLMAENAIKVTVPTQMTWRPGQYIYLRMPGISVFENHPFTISSLCSEDFPSEYGEKYKDCTMVFRPFGGFTKKVLETAAHNGPFKTYRAYLDGPYGGMQRELAAFDTVILFAGGSGITAIVSQLLNLIKRMRDGKAVTQKIEVVWALKRLESMDWFKEELRICREYAPPDTINCQFFVTTAKRYSKIDVAGRAQRPLSTAFHDKLDGFVAGIVSKRNSALIRDEAQGNEERARELRREDEDAITSLPHSKHLQPRMHPNVQTSFPPPPTAESKSKNSEKRHSLLATLSPDSHEATRRFLSPLGLATKLKTDSKESFHFPAPPQRLDAPHFQYAPPPSANSNRASFVPDTACNSYNPQDHIDDPAEAYDADMQSSEEGQLSEQFAPREYAPTPPPKDTPKMSSEIEPTPCLKPPQPAHLRQKSEELKLEIPQSNFQHSIPDPTFDFGFPSTPTLFSEEPHAFRIRRTQEERGLDHRIWSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZF7</accession>
    <name>A0A5N6JZF7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab proteins geranylgeranyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8294926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZF7"/>
    <dbReference type="OrthoDB" id="1923006at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017230">
        <property type="entry name" value="Mrs6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF4">
        <property type="entry name" value="CHM, RAB ESCORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037514">
        <property type="entry name" value="Rab_ger_ger_transf_A_fun"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00894">
        <property type="entry name" value="YEASTMRS6P"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8294926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="459" mass="50753" checksum="250DBE06033BF504" modified="2020-04-22" version="1">MESLSETQWDLVIEGTGLKHSLLAFMKSLLSLQETDAWVKRPHSRNTSFSNASATYNPDLKEKLSFSRAYNLTLSPQIIYTRSPLLSTLVSSKVYKQLEFQAVGSWFLYDDAVLKRLPSGREDIFQDDSIDNRAKRSLMKFLKFVVDYENQVDVWQDKAEMGLSQFLADSFKLPLNLQILIGALTLSLDTLEATKVGYALPRIQRHLTSIGVFGPGFGAVVPKWGGGAEIAQVACRAGAVGGGVYVLGTGIRDAKTIGNNGFTTHEIDLSNEEKVKTRYITRISNDIPPDTIRVAKIIAIVSSPLGSLFTSTMEGSPTSAVAVVVFPAKTISTKDFIQDYPVYIMAHSSETGECPTGQSILYTTTLLLESSTEQTGKLLLEKVISKFLETTEGHGGQVLYSVYYEQQGSKGKLDLSFDDQVLKDVEEEWKRVSGEEEATQFMVFEERNGMGDDDESGEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZG3</accession>
    <name>A0A5N6JZG3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8294787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZG3"/>
    <dbReference type="OrthoDB" id="2832510at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF14">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8294787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="205" mass="23607" checksum="708076D439DC1788" modified="2020-04-22" version="1">MGSKRMLDIKKKDPHTTFLKVVDTDTGAMIAKAKWNIWKGVIPSEDDLDGDYWETEEEKEGTFTLDILAVDPEYQRRGAGRLLVRWGTAIADELGYMAIVEASEAGRHLYESEGFEFVKLVETSIPEKWRDRKGEKFIWMEPALEPQPWIQAAGLVSDQSRKDLSQPQKKLNNELQSVLKVPETRLDRKSFYRCHKGLGDRELHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0K9</accession>
    <name>A0A5N6K0K9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein bS18m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_007170</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0K9"/>
    <dbReference type="OrthoDB" id="21463at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.640.10:FF:000013">
        <property type="entry name" value="37S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_bS18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_bS18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479:SF40">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS18M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8295259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="258" mass="29210" checksum="CFA52AD08EA38944" modified="2020-04-22" version="1">MLPRLQCLNAVRNAVSIPSLGMRFSTSKIASADLPAAFETQNLDSNKISGLLSLVGVAENRKALRDEEIRRRNAYNRANPQTAAQDQATFTTRTELTKQIHRRWKAGDVYAPHDLSGVEMAKWKKRGKVTRDVFDVVAFDPLATGSYKNFSIMSEYVTPMGRIRGSKETGLRPVNQRKIAKAIRRSIGLGIMPSVHRHPEVLYKARERARENDNYKSGPMWDGARLVVSFSNKNYFWPKLPRSPRPHGINKACRSFHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0M4</accession>
    <name>A0A5N6K0M4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0M4"/>
    <dbReference type="OrthoDB" id="10531470at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8295321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="131" mass="14415" checksum="CC8CC5C803D32432" modified="2020-04-22" version="1">MAAQTYTFATRPNGPRHIRGILYIPGVPTINAPSNCQQETVDQFLVRYNRSKIDWDSKASRGKFAGLGVPVFADGMQRSPKMVLTGVRGGDWVLPTPEWVAASAGRGQMGRISPGRTYITSAVSFYRYLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0Q1</accession>
    <name>A0A5N6K0Q1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_007135</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0Q1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS/mFAS DH" evidence="7">
        <location>
            <begin position="390"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="729"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="4">
        <location>
            <begin position="390"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="4">
        <location>
            <begin position="550"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="810"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="812"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="4">
        <location>
            <position position="423"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="4">
        <location>
            <position position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8295217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="843" mass="94373" checksum="E6C07BD6C67AB04F" modified="2020-04-22" version="1">MSSLMEDGKQLVLSERIPECSTAFVFTGQGSEWACMGKQLYEASSFCRTIFHQHDAICVGLGFSSFIVLLIGDDMDLGIASPIQIQLAIVSFESTLSSLWQHWGVRPSVAIGHSLGEYPALVSSGILSLSDMFFLVGLRAQIIQDSCSESTHSMLAVKVSAQHAEEILRQNQSLDWNVACINSPSSTVISGYKDDVANLRKFLDLQNIKSTVLGVRYAFHSPQMDPVLGKYRQMIKAVRFTKATIPFASAYQSDIIMPGHSISPEYLVQQTRQPVKFQPALQVLKTKAQIDDSTMWLDLGPRPLCLNMIQQSLNIPPSRLIASYKGGMDIQWRQYHGQYGSNLNLLELPSYAFDVKNYWIQYEGNWSLTKGRDTTQTQTPTSDSFKTTTLQVIESENREGRQATVIFSSNLAEKHLRIAVRGHSVNGTLLCPSSVYGDMAIGAAAYVFSKTHPNEKIFSFDVYNMEVIKPLLANDDGKDQWIQITATKQEDDEFVSISISSHESETLLNHISCVVKHGSGVDWMCKWARNTYFVKARIENLMEGIAQRSTQQILRPIAYKLFSDLVTYHKRYQGMKRVYLNSDLYEAAAEIEFQSAYSDGTFHVSPYCIDSILHISGFILNGSEMTSKDTVYISHGWRSLRIARPLSHTKRYRNYVRMQPTDTRGVMAGDIYVFDGDEIIAVCKGLKFQEIKRKVLGLLLERQSNSLAAMQGALKLPTRKITANLPIAKERRSNFGEILKIIASEAEIGVDELTDNACLVELGIDSLLAMGIVERIRVLLKCADIPSSIFFDFQTVSQLRTFFSNNVGSYESSERETTTHSDKSGSKYPRVRLGPQHASQGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0Q8</accession>
    <name>A0A5N6K0Q8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">IEC3 subunit of the Ino80 complex, chromatin re-modelling-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_007232</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0Q8"/>
    <dbReference type="OrthoDB" id="4095124at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055449">
        <property type="entry name" value="Iec3-like_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032742">
        <property type="entry name" value="Iec3_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24244">
        <property type="entry name" value="Iec3-like_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14612">
        <property type="entry name" value="Ino80_Iec3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INO80 complex subunit 3 N-terminal" evidence="2">
        <location>
            <begin position="35"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="INO80 complex subunit 3-like middle region" evidence="3">
        <location>
            <begin position="155"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8295330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="41489" checksum="9228D4AFE24B4FFA" modified="2020-04-22" version="1">MTSSLDDEILGEDVTEQEEGTQSSLSDGPKPPPYKSFKKKYRKMRIKFDEAMRQSNSLFMEEQLADETAKRLARENDRLLDLLLDVNNSAQIPADKRIDLATGGPALAKIPALATKEELAQAAEDESPEGQALYKEVQDLLKDRDGTNTPNKPSKSLAQLMATVPHISLMNPHVPPQSLADFEPPTGKKHPIAYLSIEDMDDYLYEVDAAIGYAPALATVVYPPTMQDVTLKNPHSVLNWLRRHEPKIFLQDGEGPTEKINTKPGALRGAGKRASIPTPTRLDSLEIVEEDGIGYDTTLNGPSSSKVKRKRDPEDDGGYTPKSGNPINKTKRQRPSKRKSESNVDPTASSSSRKSKSRAKNSSPVDTGPAPHPFGPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0R8</accession>
    <name>A0A5N6K0R8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0R8"/>
    <dbReference type="OrthoDB" id="3561737at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35487">
        <property type="entry name" value="DUF3824 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35487:SF1">
        <property type="entry name" value="DUF3824 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="230" mass="26082" checksum="D696D841CE041402" modified="2020-04-22" version="1">MKPLRLKLITYRLKDSTPTTPVSPIEPAPSNKSVMFAPLSPTSSRRLERIHNAKADPSTSSVNTYEQPNPSSDRRYRRRRRRKSDPSSDRPSRPRKHRKHRKRRNSDDSTSEKSEGSDRDEEVEVLPERFDREGRPLDGNGSGSRERDIAKEFGDGNEIVEKVVRGVGEVVAGKQSWGDLLMGLVKEGGMANSGGQDLEGGERDGGRQRDRVRKERRGSRSRGREKERDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2P2</accession>
    <name>A0A5N6K2P2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009133</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2P2"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8296382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="132" mass="15204" checksum="B6FE84B089317968" modified="2020-04-22" version="1">MVIDPQDRASHNIKFDRNTLALEIQPLEIAYLYESTKIMMDGKDEAFALLAGEQYRLIAFDESMLQWSFLPASNLSQASKSLVIINRIIKRGERPTNVRAAPPFRILHHFRYNVKNLMLVNLSVNRSIITTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2Q7</accession>
    <name>A0A5N6K2Q7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell wall alpha-1,3-glucan synthase Mok11-14/Ags1-like transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_009174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2Q7"/>
    <dbReference type="OrthoDB" id="512920at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047657">
        <property type="term" value="F:alpha-1,3-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070600">
        <property type="term" value="P:fungal-type cell wall (1-&gt;3)-alpha-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058655">
        <property type="entry name" value="Mok11-14/Ags1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058654">
        <property type="entry name" value="Mok11-14/Ags1-like_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182:SF2">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26127">
        <property type="entry name" value="12TM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall alpha-1,3-glucan synthase Mok11-14/Ags1-like transmembrane" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="85" mass="9056" checksum="72F2098DEF5DFC7B" modified="2020-04-22" version="1">MLLLQTLTRVHIAFTLIAAQVLGSIATIVARACAPNNIGPGPVFPDLSDGAGGLGNAWFWIGLILQLVICGGFFTFFRKEQLSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2Q8</accession>
    <name>A0A5N6K2Q8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase family 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2Q8"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="42336" checksum="3C910CA0A09D60A5" modified="2020-04-22" version="1">MELWLMPWTGPEYIDIYREISEILEEVDPVMVAVDPLFGPGLDAVRAQGRNHAVLSPNSLKENFVQLQPRGAALWKYPAVSSAYTYPVPWYLIPSNIYMNLRLAYSVLIGPVLANKRSFLKKNGIANPLSVFTVYHEDYPWITQGSEELDYPYDIIPENVVQCGPIFLSTAPAAEQDPELANWLKESPTVLINLGSNLNYDETAATEMANAVKILLDNSKVQVLWKFNKRHEFTDQFLDILEETIKSGRVRMSKWIKVDPAALLETGNVIVSVHHGGANCFHEAIGTGIPQVVLPVWVDLYDFAIRVEYLGVGVWGSRNAAPNWTAAELSTALLKVVGDSDEAISMRKRALEISKPYQETPGRIVAAHELSKWARLASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2U4</accession>
    <name>A0A5N6K2U4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Importin subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_002110</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the importin alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2U4"/>
    <dbReference type="OrthoDB" id="29145at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.690:FF:000003">
        <property type="entry name" value="Importin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000021">
        <property type="entry name" value="Importin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.690">
        <property type="entry name" value="Importin-alpha, importin-beta-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032413">
        <property type="entry name" value="Arm_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002652">
        <property type="entry name" value="Importin-a_IBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036975">
        <property type="entry name" value="Importin-a_IBB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024931">
        <property type="entry name" value="Importin_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23316">
        <property type="entry name" value="IMPORTIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16186">
        <property type="entry name" value="Arm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01749">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005673">
        <property type="entry name" value="Importin_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51214">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="IBB" evidence="10">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="7">
        <location>
            <begin position="126"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="7">
        <location>
            <begin position="168"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="7">
        <location>
            <begin position="337"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00071843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8296688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="550" mass="60147" checksum="9C87923690FB4005" modified="2020-04-22" version="1">MAERYIPEHRRTQFKAKNTFKPEELRRRREEQQVEIRKVKRDENLAKRRGITGGDGSSRPGASLGAEPDSDDDTAPTESQLNEDLPQMVQGVFSEQIDAQIQATTKFRKLLSKERNPPIEEVIKTGVVSRFVEFLRSPHTLVQFEAAWALTNIASGSAQQTQVVIEAGAVPIFVELLGSHEPDVREQAVWALGNIAGDSPSCRDYVLGCGALKPLLALLGDSRKLSMLRNATWTLSNFCRGKTPQPDWTTILPALPVLAKLVYSLDDEVLIDACWAISYLSDGANDKIQAVIEAGIPRRLVELLMHASTSVQTPALRSVGNIVTGDDVQTQVIINCGALSALLSLLSSGKDGIRKEACWTISNVTAGNSTQIQAVIDANIIPPLIHLLSNGDLKTRKEACWAISNATSGGLQKPEQIRYLVNQGCIKPLCDLLACPDNKIIQVALDGLENILKVGEMDKDAAGEGTESINRYALFIEECHGMEKIHDCQTNANEEIYMKAYNMIEKYFSDEEEGADDGQPQIAGNTFGFGTNGEQSGNFNFANGGDSMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2U6</accession>
    <name>A0A5N6K2U6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_002113</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2U6"/>
    <dbReference type="OrthoDB" id="427518at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="364"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="556"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="377"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="389"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="564"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8296692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="781" mass="86689" checksum="3CD6EE9C353C3DC1" modified="2020-04-22" version="1">MSMFRKSNDNGMLVLYEPEGDSLQISYDVILVHGLRGHRIRSFTHKNGICWPKDLLPLNRSDIRVMSWGWDSKGIRYEPKSANFFEDHALALLADIDICRPNQSNNRPIIFIAHSIGGNIVKEIEILYTHGLLNRHFSPQPTKPSNLDSAMEVVVDQNSATLGQPKQIVRPLDSDHFHLNKFPNENDANYLRVQDAINSWNRWRESKQREIRDSVNKNDHMRSVGHHSIENHESAADPIMNLDDAAPTISVIIHHTQVESILRAVIDIDSIENKIIYSTLAKNDLTAKIYTTEDAEQTYRSIDLEFSILGKSKVHSRTFIVENYLTYDIILAGSHEKKRMVVDWVSYGSDADLARDHSTPAASVTLMSTSKTPPWHNRTDDKVTKSLRSENSQVSQASKESGTKSLGLPMSITDTQALKVKPSSSPSSIGLTQGSMKALSDKFSSQSSHLTNAEGIAIGASSIASVNLLTNMASAYTSRQALEQSRISTKASTWSANISAATYAMNKDKIEHDEQRNKLLASSSSNKITTKQPSSGNMTVVTSLAKVENYAPPEIIFPSVPKNEPIRRDSRDSNDNDRPTGTFAYTSDGTAVLQTNDQDTYSMRTMDYSKENPHILKTSNSKEDISSSSHSSISIYLDSQDTTSVTHVEIPPSRKSSSKFEPLSLRQKTLFECGIYEGKGKAPIQTIPQLEKTQLSSTLQESQVIASNIPEHIPTGKDSILPGITDTSGLTLIEDERTQTILIETKSIGQLPAGTMVSNDLVDSKIDMENQELNVKSEDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2V8</accession>
    <name>A0A5N6K2V8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8032 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_009130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2V8"/>
    <dbReference type="OrthoDB" id="5599902at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058345">
        <property type="entry name" value="DUF8032"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949:SF0">
        <property type="entry name" value="RE27538P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949">
        <property type="entry name" value="WHITE COLLAR 2 PROTEIN WC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26087">
        <property type="entry name" value="DUF8032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8032" evidence="2">
        <location>
            <begin position="284"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="511" mass="56015" checksum="547057121F6A2E10" modified="2020-04-22" version="1">MASMQHHPHHAPRKQQQQQPRPSSIVHQHHQQAPPQPQHSNAYPSGHALPQYPQTATGPGGQHQELPYYQTHPSPYSTPSASGTYSSAGPETPDIMAATQHMTRAPYPPIYQTPQSNSPASVASPAHENRMYAPSSQLQQNPQMYYPGPPQQQYPPPMAQGGPSPYAQQQPPPQQQQHHHQQSMTSQPTLLMSHQANQHPMQQHPNQHQQPGMTGSPRPKMEPHVPQIARPNPPLGAQHSANGAPQMQSNNVPGTGGSGVNPNAAPGPIPATTPLVVRQDNNGVQWIAFEYSRDRVKMEYTIRCDVESVNVETLTPEFKTENCVYPRACCSKDQYRGNRLVYETECNTVGWALAELNPCLRGKRGLIQRAVDSWRNSNQDPRLRSRRVRRMAKINNRKAVQAATSHNSHMTGPSPTGMPPSANMGPGGAGSMGKPNLSGMGGPQLHHHHAHPDGSNQGGEEVVTKALSCIIQHCTLLPAFRDTYPLPRVMSSYYCIAPHCLLCIVIVLLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K300</accession>
    <name>A0A5N6K300_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K300"/>
    <dbReference type="OrthoDB" id="3534872at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="253" mass="28692" checksum="83BF43D38EE80EDC" modified="2020-04-22" version="1">MIHDTRDVQSALLQCLTKLMAAVSSSITPTFGLGELLRKSMLLDLVADIMRNMTVYNIELSPLLIQTWEFLNMVAEHDELCSLFFENRVEMKEKSSGLQRFIFPLILLPVHQSSHIDNSSPRKFYLWPLLQSCVNTANQYLLANHDDVWSAAILAERVLSVHETLTGRVSAQAVTPPMTHPSQTVTGFAVGLKELYKTGAIRKMKSKQGPAQQEEIIVEQPRKKRGYWEPLSEKGQDERDATRGRKRRNTVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K304</accession>
    <name>A0A5N6K304_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_002165</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K304"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:001516">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF49">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8296748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="419" mass="45639" checksum="8A5E2984C822021A" modified="2020-04-22" version="1">MRLMSDVEAGKETFQEANYATTNESLANTKALVWKQDLRIVPLCAGIYLLCYLDRSNIGNAKTLNASSHDDLLSDTHMTGFQYIIALMVFLIAYAVFEVPSNYFLKRLSPSKWISFLMFSWGVMTIGLGFTHNFAGVTADCFQDWYTTLLSASATFAGAFGGAIAFGVGHMNGTHGMSAWRWLFVIEGIPSCLSSIFVFLFLPDYPETVKWLLKDEKDLAISRLATEGSKVHDKGLTWQEAKETLCTWRLYAHYAIYFGISTPFSSLSLFTPSITAGLGYEDLEAQLMTVPPYAVAYVVTILISWSADHFNARALHSSTMALIGAIGFTASALLPSASYTSRYGCLIIAASGAFSCIPPLLGFLSSNIFSTASIGLAIALNISVGAPGQIAGVWIYKANDAKKGFPLGHWVNAGLLFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K324</accession>
    <name>A0A5N6K324_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Translation initiation factor 5A-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_009146</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell septum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-5A family. Hex1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K324"/>
    <dbReference type="OrthoDB" id="9975114at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140266">
        <property type="term" value="C:Woronin body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045901">
        <property type="term" value="P:positive regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000033">
        <property type="entry name" value="Woronin body major protein HEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048670">
        <property type="entry name" value="IF5A-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21485">
        <property type="entry name" value="IF5A-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Translation initiation factor 5A-like N-terminal" evidence="5">
        <location>
            <begin position="466"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="149"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="277"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="197"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="299"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="318"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00061629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8296399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="646" mass="75159" checksum="9560B5CD1BD82186" modified="2020-04-22" version="1">MYAGRSISFTQHRISIRAINSFHTHPPYLLFAHPARTTPTIIIIIIIKIFTFASLWPHLQRPRDNFLKLKVESRNVNQNVFFPLPSTSRSRDPSCDILSVVNLDFDARVPIPFSIFPSSYRSDVAVQHIQTTETHVEGELTLPHHHERVGREGQEEDAQSLYSQHTQHQHQHQHQHQHHLPPPSPQENLPPPPQRQEYLEEEIHITREEDRRSEYRPSRTEEEEVYIREERRPEHKHKHHSASFDINTPHHHRHFEASFERDSDRHHKHTEVNIELPRREHNHHHHHHHRRPSSEVDYQLERVRQPSRYEHSELDSASEFSVPQKSPTETQIDFVERQYRSRTQPTYKEDPVIVDPPQSRVSEPRYIEETRVTETTIVPAPARSTHSNKPKSTFYEEKFEEVHVKQPRTPARSTFTEEIRDRGLVKYSPPAPKSTTSNFKPVNLEMGYYDDEASAPVVAAPKQPPNTVTIPCHHIRMGDLLMLQGRPCQVIRITTSAATGQHRYLGVDLFTRQLNEESSFIANPSPSVVVQTMLGPVFKQYRVLDLQDHTVVAMTETGDVKQAVPVLDQSNLWTRLKEAFEGGRGSIRIMVKSPCNCHTMAYYWQPFQGGVFFFFLFSLFHDFFAFSEGNLNDDGGRYGFKLINEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4S8</accession>
    <name>A0A5N6K4S8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Non-reducing end beta-L-arabinofuranosidase-like GH127 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4S8"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049174">
        <property type="entry name" value="Beta-AFase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049049">
        <property type="entry name" value="Beta-AFase-like_GH127_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43465">
        <property type="entry name" value="DUF1680 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G08910)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43465:SF2">
        <property type="entry name" value="DUF1680 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G08910)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20737">
        <property type="entry name" value="Glyco_hydro127C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 C-terminal" evidence="2">
        <location>
            <begin position="71"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8297307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="187" mass="21522" checksum="0B0BE4EC9D5DB2E9" modified="2020-04-22" version="1">MGWEDPIRPQDAPRDISNNQNKNTWMGEQLDGKITTLCKNMSQRNVDTPRARRTHSNFQLHIPLEPRYISPHPYTNQNIVALARGPIVYCAEDHDNPWVNDHFKSLVFSTRGEITEKDADVNNEPYKQLTALGAATRFRLPEQARPDLGHNVDGFSEVDIEELHFIPYALRDNRGGKGHMRVGLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4T9</accession>
    <name>A0A5N6K4T9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Anaphase-promoting complex subunit 4 WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_002721</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4T9"/>
    <dbReference type="OrthoDB" id="10264376at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051858">
        <property type="entry name" value="WD_repeat_GAD-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017">
        <property type="entry name" value="GASTRULATION DEFECTIVE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="105"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="216"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="329"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="458"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="505"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="568"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="571"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8297376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="598" mass="65108" checksum="71605B982F233727" modified="2020-04-22" version="1">MSDDEDFQVEVPELAEDDPMRAFLPTSFGKKSKEADVAAQINRTKRPAENKVDTPKATEEDGQQKLAPEPASKDWGSDDDDDEDSDSDGGSDDDDEFPTSHELVLKTHDRPVTTTTLDPSGSRLITGSNDCTLKFHDFASMTPTTLRSFKSVDPNYSKTSANSETHPINHVEFNPHAGGTFLCISAHPQAKLMNRDGDVIGEFVKGDMYLRDMNNTKGHISEITTGTWSPIDKNICVTAGTDSTLRIWDVNVRRCQKEVIVHKSKASGSAGRTRMTAVVWGSPAQGGNNLLVSAALDGSLVMWSGNGPYARPTAEIRDAHIPDTWTGGIDISPDGRMVVTRGGDNLIKLWDTRKFKTPVVTVSHPSTSDVYSVTNIKYSPNGSNIITGSASGHLHVLNPGNLKPELVTPVTAGSPLITVQWHPKLNQIVTGSANSEVHVLYNPNTSVRGAVDVMSRAPKKRHVDDDPNFTTDQSVGMSGDSIVTPGGLMSNTSATSFSARHPTIGLTASGRSRDPRRPNLPLVTPFAKSQPDEKHINESITLSSMRDEDPREALLKYAELAKNDPLFTNAWKETQPTTQYAELSDEEDEGPDKKKVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4Y7</accession>
    <name>A0A5N6K4Y7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cyclic pyranopterin monophosphate synthase</fullName>
            <ecNumber evidence="3">4.6.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_002553</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.17" evidence="3"/>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4Y7"/>
    <dbReference type="OrthoDB" id="429626at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01420">
        <property type="entry name" value="MoaC_PE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21117">
        <property type="entry name" value="Twitch_MoaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="entry name" value="Molybdopterin cofactor biosynthesis C (MoaC) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01224_B">
        <property type="entry name" value="MoaC_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="MoaA_twitch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047594">
        <property type="entry name" value="MoaC_bact/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050105">
        <property type="entry name" value="MoCo_biosynth_MoaA/MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960:SF0">
        <property type="entry name" value="MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="Molybdenum cofactor biosynthesis protein C, MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="380"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8297174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="626" mass="68430" checksum="917A64B015225FB9" modified="2020-04-22" version="1">MPEEGVPQSPQPDLLTTPEIVLLSSIFVSQGVTKIRLTGGEPTVRRDILPLMQQIGGLRSQGLRELCLTTNGLNLARKLDGMVEAGLTGVNLSLDTLDPWQFQIMTRRKGFEAVMKSINRILHMNKLGAGIKLKINCVVMRGVNEREIVPFVELGRDKDVEVRFIEYMPFDGNKWSQGKMLSYNEMLDMIRQKYPTLRKVADHKNDTSKTYEIPGFVGKMGFITSMTHNFCGTCNRLRITSDGNLKVCLFGNAEVSLRDILRKSNGNQPIDEQAFEAMKQIEMSRRQGFVDTHSALGSSANERELLEVIGMAVSRKRAKHAGMGELENMKNRPMILIDGKYPHSPKTLFPEVGSWPLNRSYKLPLNFLADMPPFNSARLYSSKSTPAQVNKADSTGGKSSLDDLSNSSPSEAHKLTHLTKSGDAHMVSISSKQSTKRTAVAVCSIHFSNNVAIPLIRDNRAKKGDVLGVARIAGIMAAKRTSDLIPLCHPIAITHVSVDLQILHEDGYGTASSSPTSRTSASLPVTGQGGGYKRPLSVSNFGPSNEFGSVEVKATVSCDGKTGVEMEALTAASTAALTIYDMCKAVDKGMRVEGLRVVRKEGGKSGSWVEGVLDSEREGKSEVEIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4Y9</accession>
    <name>A0A5N6K4Y9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_002727</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4Y9"/>
    <dbReference type="OrthoDB" id="3502705at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8297383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="380" mass="44106" checksum="6FDD94EA7E3EE83E" modified="2020-04-22" version="1">MDLIVSEDDDGINFSEFICKEEGYRAVETPSDSILPWDWPIDVIEDRNTVRLERGTEVILGGQYFVKQSATIPSSYTVIRIIFAKLPPILSGLHCLTETVSANYITWNKVYSLFPNSVLRHEPVWVSGRNVGYDQLAPAYRDNEWNLIMLNPLEYGQQGPETHTLNGKRLYRPFVPNQARWIADRYSWVIKHPALPLNLSKPNEIKNPKVPDLATELNFFTMTTNFPHESFASEGRPFYSIESEPYYTTSLKHCYGNTHRNDFAMTTPSFWSYINNQLVSYSQKQERDKLSLEQKAELSMHRAQEPAFYDDDHENPIDNLPDCWEFLDENGQIERLFKEWKKMRGSEMNDEVEELQGDSGESENANRTKLGLMNFKYDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K545</accession>
    <name>A0A5N6K545_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001524</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K545"/>
    <dbReference type="OrthoDB" id="445712at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CC tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3090.10:FF:000011">
        <property type="entry name" value="tRNA nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3090.10">
        <property type="entry name" value="cca-adding enzyme, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734:SF5">
        <property type="entry name" value="CCA TRNA NUCLEOTIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734">
        <property type="entry name" value="TRNA-NUCLEOTIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81891">
        <property type="entry name" value="Poly A polymerase C-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding" evidence="2">
        <location>
            <begin position="34"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8297718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="339" mass="38429" checksum="F2F74434CD4ADD8C" modified="2020-04-22" version="1">MEAKLIKTPLEPYTTFMDDPLRILRLIRFASRLNFKIDPQSETCMSNPAIMEALKLKISRERVGVEVEKMLKGNNPRHSLHLFDRLGLYSTIFTDPTANEIPVPDTSTWRIVYDCLEEMKSNETPGSIYKSLVRSDDAKYLAWILAALTPWTAIPPAQATKPGGKIPQPYGFLVAREGLKAEIKLCNIAAGAFKQYAEITELKASIQRNDPHIHQRDVVGMMIRKWDSQGGQWKLQALFALLVEALKLKSAEGYELLFSEWQRFIDHLKELDVMDAPAIRGIVDGKILSKALGVKPGKWMGPALDVCMEWQLRNPDSTDAEVAIEEVRKRQKELDIPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6W7</accession>
    <name>A0A5N6K6W7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglycerate mutase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6W7"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF32">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G10590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024881619" description="Phosphoglycerate mutase-like protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="40139" checksum="DAC518492DF89D0A" modified="2020-04-22" version="1">MLSLTVLLSILSVVGATPAPIPTPAPYYDSLVPRTKPGVGSHGTTWVNYTAVPGFFLQDDEKTDPTIFDYTKENFGLINQTYPTDFQLPKDATHWQRFERYVESLNKNASSTVNYKVLFLARHGEGFHNAAETYYGTPNWDCYYSLVDGNATVTWADAHLTPNGIAQAKIAANYWLSNIQVEKTPSPQSYYTSPLYRCLQTSNITFSTLSLPESRPFKPLIKELFRESISGHTCDQRSNRTFIQESFPTYAIEQGFSEKDPLWRPLFGEPAFNQDIRSKEVLDDVFGSDKNTWISITSHSGEIASILRVVEHRPFKLATGAVLPVLVKAETVTGEAVTLSPLPWTPLKTCTSPPPPGATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6X9</accession>
    <name>A0A5N6K6X9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calcium channel YVC1-like C-terminal transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_002026</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6X9"/>
    <dbReference type="OrthoDB" id="310870at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF5">
        <property type="entry name" value="ION TRANSPORT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="3">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8298296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="452" mass="50121" checksum="1F20542E535FB8E7" modified="2020-04-22" version="1">MAKDFVKFMVIVLVLYLGFLTTFTLLARDSFTLGEMSWVLIKVFFGSSYLGFDIMNQISPQLGPPLMLIFVCMTNILLITSLISILSDSFSKVISHAREEYLFVYSVYVLEASTSNRLTHFYPPLNLIPLILIRPLRLFMSSSTLRRTRIGLLKATHAPIVLAINLFEGISEHLQDPSSFPHTPIAGGPATPTHSGGIGEASGNDTLGATSTAEPAYKGKAKKKFLTSRTGTNQSLHFMDKPSIARDGEASPLVSGRWEGPVRGRKEIISDHYARGNCGDEKNGNGNRNGSGSGKEPNRKLVFKGEDSGLGDDANGESSGATERERMLERKIDELGRKIEELTRLFVADKGAGFGGDDELNLSIHLSLYLDTYLPAYLLIIRYLSNSAIFLIILSFPFIIISFVLLGRYSSMRLSAPSIHPSIHPFIHSFIYRYSYLLFAICYLLLAIYHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K796</accession>
    <name>A0A5N6K796_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">4-coumarate-CoA ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_000828</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K796"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05911">
        <property type="entry name" value="Firefly_Luc_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000007">
        <property type="entry name" value="4-coumarate--CoA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000003">
        <property type="entry name" value="Long-chain-fatty-acid--CoA ligase FadD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF424">
        <property type="entry name" value="ACETYL-COA SYNTHETASE-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="26"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="7">
        <location>
            <begin position="462"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8298649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="563" mass="62892" checksum="D11EB848023789E6" modified="2020-04-22" version="1">MPISSRWQIDIPSISLPTYLFTSATHSLPDKVAYYNASDPSRYLTHSTFRLYSQRLAAGLIKNGLRPGDRVLLFSGNNLFFPVVIMAIIMAGGVFTGANPGFVERELVYQLRDSGARFLICGEESLGVGVKAAEEVGLGREGVLAFHDRFEEDGGGREVGNDHEGVRDWRDFLESEEVGRSFQWSEDVDPKETVCCLNYSSGTTGVPKGVMITHYNYVANSMQYKSLHELHPDTPERNKKAKWLCFLPLYHAMAQTIFGAVAPKRGIPVYIMKKFDFKEMLEAVQKYRITTLTMVPPVVVLLVKSPLTKQYDLSSIIDIACGAAPLSGEVIEEVEKLWPSGRQGWGMTEGTCSLLGWDPRLDPHPDSVGELNANCHAKIVDPETLEEVKHGERGEIWVQAPNIMKGYWQKDAATQETIVNSSDGRWLRTGDIAYVDSQNRFYIVDRMKELIKVKGNQVAPAELEALLLEHPGIADVAVIGVMIEDGEVPRAYVVKSGNEKGRVLTKEEVVKWVEERTSRFKWLKGGVEFVEAIPKNPSGKILRKILREKAKEEMSGNTVKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9B2</accession>
    <name>A0A5N6K9B2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9B2"/>
    <dbReference type="OrthoDB" id="2993351at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="195" mass="22121" checksum="2F47C8E81872D404" modified="2020-04-22" version="1">MKGFGWQEMEDVIIDVWISSSKPTMKRYRWVFPGKDGFEITKGEGVLREYHFGRRTMVHRGFRYHTPKGTDVGINVNTLQDIDQWSLTVHKYNGLDHEPQYNAPKHTGELPTSKFEDEKRYPGAYHCGAKKNASRSATAAYVAAAEPSSVTRTKTKLAFPGLQTSRPTPLGKATTYSNFALRAALRSVLKETYMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAL1</accession>
    <name>A0A5N6KAL1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA/RNA-binding protein Kin17 WH-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_000449</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KIN17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAL1"/>
    <dbReference type="OrthoDB" id="10266249at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2030:FF:000001">
        <property type="entry name" value="DNA/RNA-binding protein KIN17, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2030">
        <property type="entry name" value="DNA/RNA-binding protein Kin17, conserved domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019447">
        <property type="entry name" value="DNA/RNA-bd_Kin17_WH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037321">
        <property type="entry name" value="KIN17-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038254">
        <property type="entry name" value="KIN17_WH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12805:SF0">
        <property type="entry name" value="DNA_RNA-BINDING PROTEIN KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12805">
        <property type="entry name" value="KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10357">
        <property type="entry name" value="WH_KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01253">
        <property type="entry name" value="Kin17_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA/RNA-binding protein Kin17 WH-like" evidence="6">
        <location>
            <begin position="10"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="137"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="254"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="137"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="197"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8300236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="300" mass="34459" checksum="701246FB8A4E1CC0" modified="2020-04-22" version="1">MHTQSESHVRQMLLIGEDPKKYINDYSNQFQRDFLQLLRTSHGEKQVNLNHFYQEYISNKEHIHMNSTKWPSLTEFAKFLGRESLCRVEETDKGIQVAWIDNSPEALRRQDAIRKKERQDKGDEEREQMLIREQVRRAKQDAEARGELEMNEQERELKREEGEKIKLSFGAKPTVPKVESKAVESGKDETPTSDAPSSEKAKEEDTSSETLAKDDGKSTEDKNPEAAPAPAKVSLKMGFQGKPKNVFAVAKKNALGGKKASAFEQPKKMSEAERIMKEEIERKRSREQSHGGPSQKRQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2024-05-29" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAM6</accession>
    <name>A0A5N6KAM6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_000451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAM6"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8300240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="96" mass="10793" checksum="DFF75F697B00AE03" modified="2020-04-22" version="1">MEYQTEFCIETTSKSCVNECMQSQINQAFEHSSIQAFKHSSLQFSQESLNPFEPTYRCFINLFESSNLLSSASHVRAATGSSHLASRILISSVSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAN3</accession>
    <name>A0A5N6KAN3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAN3"/>
    <dbReference type="OrthoDB" id="5421784at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="101" mass="10666" checksum="2CA07C74CDCCC907" modified="2020-04-22" version="1">MSGSSFYPSGVPAVPNPNTLSGTSFYRDSQGFYGGQPSPPLDPPNRDSGVPVMRPSPARTPVTEHGPFAEPPGPIPPRPDLLGRSHPSQDGSHASRFTEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAN6</accession>
    <name>A0A5N6KAN6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tuberin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAN6"/>
    <dbReference type="OrthoDB" id="19311at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033596">
        <property type="term" value="C:TSC1-TSC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032007">
        <property type="term" value="P:negative regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027107">
        <property type="entry name" value="Tuberin/Ral-act_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024584">
        <property type="entry name" value="Tuberin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063">
        <property type="entry name" value="TUBERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063:SF0">
        <property type="entry name" value="TUBERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11864">
        <property type="entry name" value="DUF3384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tuberin N-terminal" evidence="2">
        <location>
            <begin position="112"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="257" mass="28193" checksum="BB0AC0F5D8DA77C4" modified="2020-04-22" version="1">MYPPFTNRWNFETESRVQRNTRASNPRASDPRASMPPPLGDAAQTPEPRSSSGIASVFKSLTGGKITKSPSTQSPATGPLQLDNGSIPQKLSHGGALNHEPSLEQLQAGHSLSDRISAAEYLRRAVIDYPVENVSLIFIAGRDLIEPTQTQQARIAGFGLLTACVQCASSNDPERASFFRVLSHPTTREDFHLQLVSLIELSRHGKDLSGFHYDLLPLLTLWLKDTWSAATLERNARKKATPSELLAQRTSALRGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAN7</accession>
    <name>A0A5N6KAN7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribonucleases P/MRP subunit Pop8-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAN7"/>
    <dbReference type="OrthoDB" id="5530243at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000171">
        <property type="term" value="F:ribonuclease MRP activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034965">
        <property type="term" value="P:intronic box C/D snoRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000294">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, RNase MRP-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020347">
        <property type="entry name" value="Pop8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049128">
        <property type="entry name" value="Pop8-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28173">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28173:SF1">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20976">
        <property type="entry name" value="Pop8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonucleases P/MRP subunit Pop8-like" evidence="2">
        <location>
            <begin position="43"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="155" mass="17274" checksum="700B612C337B4A05" modified="2020-04-22" version="1">MTETTEAIVDAPMQEAPPTSTRSKRKQTRNGHEHKAITIRAPPFSYIHLELQTSPLKKQQLDDITAKSYLTSALTQFLGLHGAAIPIDILKTEGKDVWIRVMREDTSAAVAALGGWVKGMEPLRQVLNGGMVPITDHPERHDGFTRQWFYGGQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAN8</accession>
    <name>A0A5N6KAN8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_000416</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAN8"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8300191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="80" mass="9149" checksum="429C001EC718C231" modified="2020-04-22" version="1">MKNLKGTLLLFITFSNIQDNLLNPIISTYSYLSDHKALHKDISKSRSLPLPIYKHTTNNNSTDSFSETTLAKHHNLQNSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAR4</accession>
    <name>A0A5N6KAR4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAR4"/>
    <dbReference type="OrthoDB" id="3248508at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842:SF3">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="543" mass="59708" checksum="D523A7B9322AEF42" modified="2020-04-22" version="1">MTDIILLGHSMGGILSSEVVLQPPPPPANRPFRHRILGTISFDTPFLGMHPGVVVSGIGSLFRPAPDPPSARTGSLSPTGASSPSINGPVSTPSLAGTPSGSNTMYQGSDGQSMTSLTTPPPNDPHYNAPFPNDVRIPERKGFNNFLHFVNKHAEGVGAYAKLSGLTSATSQYFMSHLEFGSCLADYPGMMNRYSKVRALEDVDELAGRSNSVNQDGNSRRRFINYYTASTGRPKKPKDSTSEESINNNTIPPEAGMGSLSLGDSEPQLPKPVENTTPTGHDVDSADDIHMKQVEEQMQELGDNSGVQDDAPQSPEMRHIDSVPIEDDEIEPISNPSHAKESENATQKAPTEPPLPPIPDAPTEPEPIDLDLYTDKDSRKIAEKEHKRIMKAYNQALKDRESALKDRRKLIEKREKKARQEEEKQLKAQEKQRLKESKEAEKRHDTLNPKSPKGKDNSQKTEKMEKMEKPKKDKKFCMLPPESGGKQDVCWVRVYMEGVDEVGAHCGLFFPGPQYESLVGNVGERIGTWVKEDAVVRAVLSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAS0</accession>
    <name>A0A5N6KAS0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alpha galactosidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAS0"/>
    <dbReference type="OrthoDB" id="5795902at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha galactosidase C-terminal" evidence="1">
        <location>
            <begin position="14"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="172" mass="18356" checksum="1F23B54779FD2144" modified="2020-04-22" version="1">MYAADAADENSVATIQMWSGSLQSTTNSTTSDMVLLLINGGNEPLTMNATLADIFIDFGTAGTAKQVSMEWELRDLWANRMDNATAQAIIGASTATDNATTGYNATTVGDGRYNATEMSYKDGLAAGRSELLGNLTGTVKPSGTVFADVEAHGVKMFRMRPVETGKRKRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAS4</accession>
    <name>A0A5N6KAS4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RFX1-4/6/8-like BCD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAS4"/>
    <dbReference type="OrthoDB" id="10056949at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039779">
        <property type="entry name" value="RFX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057321">
        <property type="entry name" value="RFX1-4/6/8-like_BCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12619">
        <property type="entry name" value="RFX TRANSCRIPTION FACTOR FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12619:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR RFX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25340">
        <property type="entry name" value="BCD_RFX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RFX1-4/6/8-like BCD" evidence="2">
        <location>
            <begin position="6"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="366" mass="40632" checksum="73628BB4671021C3" modified="2020-04-22" version="1">MPVQKLFADKALAPWINQCDIIMYQNMMRVVAPLTLQVVPKVVLDTLRNISDRLVKHIQNSFHGQPIHVIEAKVGPATTFASLLDKELRVNLTAHAAANMLSNPYNRDTMYEDFITMVNVRKVAESVPTRGMDDVVNLLITELRDLLDPSEVSWELERQTPFGEMAARMGRQRQASVHADPTTENVLDRWVNMLLSLTGKFPYATHAEIVWCVQKIGTAVMRDLTIAQGKSFGAWWVTKCWIDEMIAFMAEQGGFMQRETIQSGMGDMSQNPAASRRNSQQGGRYSSGSDDFLARGVNGERGAGPRPMDHARDAAMNAAAGHDDSGIGMRTPEDEFAMGKFGFTQDDVHASMESNPLHTMSQGSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAS6</accession>
    <name>A0A5N6KAS6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA/RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_000474</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAS6"/>
    <dbReference type="OrthoDB" id="69928at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018834">
        <property type="entry name" value="DNA/RNA-bd_Est1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019458">
        <property type="entry name" value="Est1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045153">
        <property type="entry name" value="Est1/Ebs1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696:SF36">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696">
        <property type="entry name" value="SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10374">
        <property type="entry name" value="EST1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10373">
        <property type="entry name" value="EST1_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Telomerase activating protein Est1-like N-terminal" evidence="3">
        <location>
            <begin position="14"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="DNA/RNA-binding" evidence="2">
        <location>
            <begin position="118"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="492"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8300273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="806" mass="89597" checksum="3E0DEC5958426A70" modified="2020-04-22" version="1">MLPRSVKFVAHYRSADQKRRAVERRKLEKHYVDFLKTSQYFYKGYIQRVASHFGPLPALQRIANRLSLSPLSVDKPIKAGRTLENLLKLSCHFTLLRLGDLSRYRNDLRTKDRSWEPALGYYYLAEALYPDSGNAHNQMAVIALADGSHLDALYHLLRAVAVEEPHTLARGNLAIEYKKISTTWEKERQSRRRPAPVESALVIWFVRLQARFYKGVEFSTQGELENEVLGQLASALKDQSFEETLNKLVLINMAANYLATQRLTEAEGGVTDDLKKSLYFLLGFNLQVFCILLQALISELADAAEAENLESLTATDGSGDSFEKLSPVAIRVLPAIRQYFAWVISQRLLLVGLANGVDSESTGPLVGHIQRMWKTAADALTALVSFFPVISLPYLPYMLPEDEQTVGFKPLRDPPHGLEEYSLYNKDDGSLKAFISDGIMRQPESENYARVRDILRAGMALHFEKPCPILMNDDNRFVYGFESSASPISDNSTMPSQPTKPTSTTQNYKNSSGENAVASDSLGIMDTEMNRMVDDLLEPASLAPSDDTSYGMNSSIANAIFPPIGSERTRLSRLSTGNQITPTKAFPSLPGIWGSPFTPKPNELRPISPEKISSSVGFPSMNYSTNKDKLAAAAALDSMTGMQRRVSNGVATNARRQLSSFETSKPINQILQESLAKQFEPMSLASSGFSSNSSIYANNSPPKAYYGRTLDRPSLSGHDSTVYPGASDFERNTMLQSSFWNASQTNNDSYKHTPPARQGRQALISKKFLLLRSRGPYQESLAESISALLIVEDRKVNASCTTSFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAS7</accession>
    <name>A0A5N6KAS7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tuberin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAS7"/>
    <dbReference type="OrthoDB" id="19311at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033596">
        <property type="term" value="C:TSC1-TSC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032007">
        <property type="term" value="P:negative regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027107">
        <property type="entry name" value="Tuberin/Ral-act_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024584">
        <property type="entry name" value="Tuberin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063">
        <property type="entry name" value="TUBERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063:SF0">
        <property type="entry name" value="TUBERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11864">
        <property type="entry name" value="DUF3384"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tuberin N-terminal" evidence="2">
        <location>
            <begin position="112"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Tuberin N-terminal" evidence="2">
        <location>
            <begin position="243"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="894"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="649"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="962" mass="106086" checksum="C34C1BAA7FD321D1" modified="2020-04-22" version="1">MYPPFTNRWNFETESRVQRNTRASNPRASDPRASMPPPLGDAAQTPEPRSSSGIASVFKSLTGGKITKSPSTQSPATGPLQLDNGSIPQKLSHGGALNHEPSLEQLQAGHSLSDRISAAEYLRRAVIDYPVENVSLIFIAGRDLIEPTQTQQARIAGFGLLTACVQCASSNDPERASFFRVLSHPTTREDFHLQLVSLIELSRHGKDLSGFHYDLLPLLTLWLKDTWSAATLERNARKKATPSNIVTEPASSQLLSQILEICTSSATETDLKACNQVFDAVITYGDIPDSKLQPVVKVLCSIHSSLWNVHQDAWRCIGNLCKSHHGLTMVRILIEILGKPLLDKSDDKQYSQNIKEVRGAISALEKLFARDAKNGYPLVPFTLLMASLRKVLELDRTAVDCDALQLIYSLFTHEGGIMQNVLVEDWSPMFEIVSICSRRIPDPVSNRSQIYHTISGSAPAKDESPQQKFITKMGELIGGLIVRVEQLLISPPLDFVQKDDCLKFFVRSHTYLPDTCAKLVIDHFIDYKCCSPSDLQWKDNINLILGGFLADRSRPSDIRLHALKAVTDVYVIVSVTDQPEVFEAFAVTILAYVREEKDIAILQEFIDFAVVMAEQTQDESLFQHAIDVMRSVVTSDRMQSPLGSPPGPHHGILSSKSASSSATPSIVHSPSNVVVKGFIRIFMRTMFTEIPKSLRVFEELLAIAQASDCPTDSRISALKMFFRLRADAMNRIFLTPFTESDALAASLYRTADSLASKHAADDAAQQSRVARADEFNSRLARSTSGGQAQSLPKQTFRLGSGMNRTLQRNHQMWMSPDADALPDTTNGNATLRLVSIIENIDQKFTAQDLDAPDLGSDQVGLQELVAHGNAAEASVAEEKPDLVTDALNDAFHTPIESMDPSSINTEGQEPGHSDELNSSQPVVQNILNIGSYLDVLCQLLDCGFVNPPDKKAQIFVVRFNQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAS8</accession>
    <name>A0A5N6KAS8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_000476</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAS8"/>
    <dbReference type="OrthoDB" id="10267824at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000020">
        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000006">
        <property type="entry name" value="60S ribosomal protein L8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_uL2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="5">
        <location>
            <begin position="11"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="4">
        <location>
            <begin position="96"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8300275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="320" mass="35583" checksum="CAA4D6908C4F50CC" modified="2020-04-22" version="1">MGRVIRNQRKGRGSIFTANTRLNKAPAQFRTLDYAERHGYVRGVVKDIIHDPGRGAPLAKVVFRDPYRFKLHTETFIANEGMYTGQFIYAGKNANLTVGNVLPLGSVPEGTVISNVEEKAGDRGALGRTSGNYVTVIGHNPDEGKTRVKLPSGAKKVIKSSARGMIGIVAGGGRTDKPLLKASRAKHKFAVKRNSWPKTRGVAMNPVDHPHGVCKTCHFNQKQALIRNRVVTINILVKHPQSQDTPHKVKRLVSLLREELVCYVVPKRSRIERVEGIFITSDMLGLHLCNLGWISARMTEKTSTKQSCVLWHDLLMIRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KB36</accession>
    <name>A0A5N6KB36_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_000587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KB36"/>
    <dbReference type="OrthoDB" id="2127032at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000030">
        <property type="entry name" value="NAD binding Rossmann fold oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF6">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8300410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="228" mass="25105" checksum="B1BF9DB160F79242" modified="2020-04-22" version="1">MSQPKSQLETFKAWAGVDSDISYYLNSHHIDICESMVSQQGFFPVKVSASASKGTAVGLGCDPITEDTISLLVHWVKKDDPSKRATGVYTASWTAPQKAGVHSNQYFHYMASGGEIRIDQAKRGYDVADDNVGQLVWYNPFYMRYAPDEEGNFAGQTGYGYISFEKFVDGCRLVNRDGVSAVKVLDDRGLPTLGNTVGTTAILEAGRRALDEDREVEIKVEDGVWSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KB43</accession>
    <name>A0A5N6KB43_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Guanine nucleotide-exchange factor SEC12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_000519</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Golgi apparatus membrane</location>
            <topology evidence="10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the WD repeat SEC12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KB43"/>
    <dbReference type="OrthoDB" id="16538at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003400">
        <property type="term" value="P:regulation of COPII vesicle coating"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045260">
        <property type="entry name" value="Sec12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23284">
        <property type="entry name" value="PROLACTIN REGULATORY ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23284:SF0">
        <property type="entry name" value="PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 10" id="KW-0813">Transport</keyword>
    <keyword evidence="2 10" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="419"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="427"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="438"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU369019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8300332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="540" mass="59606" checksum="6662C300336F798A" modified="2020-04-22" version="1">MDFIQTGKDDYLFAYADDHDIYIKKLGSIDDGTEPERVYITPASRSKEKVTLPSFRSIRWLTKDFILMLTNIHSQGGVVLQILRLPPSGKGQCRIAQSHRLPSSITKATGLAVSNLTPPVTPDAEQRYTQFVIAVAGHDISISLLKVDLQHELDNYLVTPIKPFRTFKNVHPLQITGITFSTFTPPAHPVTASTPPQYLKLASVGVSNTVIVHTLPLFPVPLSVQKGQSRTPRYVVALPSSKAIYSLGIIISIVAALLIAILTQSVMEIRGVVKPYLGAANYLSVPLQEVIGKPFTFPSNYLALSKYTSTGTSTSTSSTPDFFASLRSSTPNSNSPPRHIYLHHGPPIPDIGTQETSSEITSPELSSSIKAALHDEKIHPEGKSWDELTAPQKESWKKKLKDAGHWVEEMGETIFKGIGGEDAEDSAELKRKEEGVKGKARQGKARQGKQRSMSGGFHDEKKSKRYTYMYYQLVWVFIKHRFIPRYSFTPRKKGTFLPSISPCLLSPLFFPSSPYPSAQIMHAMTSSSSSSVLFSSAQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KB49</accession>
    <name>A0A5N6KB49_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KB49"/>
    <dbReference type="OrthoDB" id="498204at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000516">
        <property type="entry name" value="FAD-dependent oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF150">
        <property type="entry name" value="OXIDOREDUCTASE TDA3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="30"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="438" mass="47376" checksum="33C2559AD454ECBC" modified="2020-04-22" version="1">MATSPTSPTSPTSPTSPTSPTSLAAPRRNIVIIGGGIIGCTSAYFLTRHPLYNPSTTKITIIEAQSIASAASGKAGGLLALWARPSSIVPLSYKLHAELAKEHDGAKRWGYRQLHCGSIGAKARLISEADPKETMENGGEAWKKLPKTDMKKQKKWGGDLPEDLDWFETDNIKWYSEMGTPETTAQVHPYQFTTSMADLAVEKGVAIVYGSVTAIDYTGNSVKGVTYEDKETRHIHTLHANDVILSAGPWTSHIWPEAPIVSQRAHSVVIEAEVSPWAIFTEIDLPKGFGRKTEDGAKKRKHDKMVNPEMYARPDGTVYACGEGDETVPLPKSSNLVVCDESSCDDIIDYVGSISDPMRNGKVITRQACYLPLASNGGGPLIGHTGIRGLFLASGHTCWGIQNSCATGKLISEFVFEGEAKSANISSLDPRKVLNDYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCP3</accession>
    <name>A0A5N6KCP3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCP3"/>
    <dbReference type="OrthoDB" id="10254721at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="91" mass="10476" checksum="FBF2F700D53B3E30" modified="2020-04-22" version="1">MLKLVAWDVVLYIPNYFYISCRLSNPYPDFLTHSFILSGLLSKLPLTEKAAVNFHHEGGRKSSIKQSYSTPASRLSSHRRHPTPHNIGFRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCQ0</accession>
    <name>A0A5N6KCQ0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCQ0"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="96" mass="11307" checksum="ADBA503E435BCBDC" modified="2020-04-22" version="1">MPAQVYTDLDSHDSTTTPLDVIQAIKTMSCEVIGTDCFCKYKLTLYSIYYELDQHTFIYFWWLLLVLTWSVKVAETPGFEVQYFLFGSLKQHHRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCQ2</accession>
    <name>A0A5N6KCQ2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCQ2"/>
    <dbReference type="OrthoDB" id="434258at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025040729" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9397" checksum="B8401C7CD9EE864F" modified="2020-04-22" version="1">MRYFSTLLIHLQIGVSAQLLFTTHFCSRYIHVLLNFITDWLPRTTTYNESTGYQIKRLGNLDDNATMTSFRYPSKIGSGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCS5</accession>
    <name>A0A5N6KCS5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCS5"/>
    <dbReference type="OrthoDB" id="1733909at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="87" mass="8845" checksum="8FE567F36C5C8048" modified="2020-04-22" version="1">MIAAGIVDPFKVVRTGLVDASGVASLLGTTEVAIVEAPEEKGPPAGGMGGMGGMGGMGGYKNQNTRLSLICLRNLPSDNVVPDIKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCW4</accession>
    <name>A0A5N6KCW4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arginine N-methyltransferase 2</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_003164</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCW4"/>
    <dbReference type="OrthoDB" id="19014at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019702">
        <property type="term" value="F:protein arginine N5-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000541">
        <property type="entry name" value="Arginine N-methyltransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017408">
        <property type="entry name" value="Arginine_N-MeTrfase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051038">
        <property type="entry name" value="RMT2/GAMT_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026480">
        <property type="entry name" value="RMT2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379:SF1">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038148">
        <property type="entry name" value="Arginine_N-mtfrase-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51559">
        <property type="entry name" value="SAM_RMT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RMT2" evidence="9">
        <location>
            <begin position="189"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8301280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="360" mass="39449" checksum="061A5EA002D3939E" modified="2020-04-22" version="1">MDDPAFATETDTTTQSILLAASNHDLPALKPFLRVPGAASVQDPETGFTPLHAAIASCEDSPSPDDIEAAKATIKELFLSGAIWNDLDANNETPGCLAWRLGRRELYELVVDAGVRAEILMNLMGGYEELSDEDEDEDEEGGEVEGMEIVENVETIVDGENTTTEETAEEATNGQAAETKGEVTEIPKKDVNSADYLQSKLEFTDDKLLDADANGVMMAWETSIMQRTVDLLIPASSPPLRILNIGFGMGIIDTMFASTSPASHHIIEAHPDVLAHLQTPGHKFGKEWEASAPEEGSYKIHGGRWQEILPILLEENLQFDVIYFDTFGESYMELKKFFSEYVIGLLSENGKFSFFNGFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCW7</accession>
    <name>A0A5N6KCW7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA replication licensing factor MCM4</fullName>
            <ecNumber evidence="10">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_003171</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="10"/>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCW7"/>
    <dbReference type="OrthoDB" id="10251574at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1640.10:FF:000011">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM N-terminal" evidence="12">
        <location>
            <begin position="235"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="MCM OB" evidence="13">
        <location>
            <begin position="402"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="335"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="131"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8301289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="512" mass="56274" checksum="93DF0D8FA77B7425" modified="2020-04-22" version="1">MSSPASRRQRNSQSATPRRTSARNSQALPSSPQDPAAAQLQNEAASSQGATGTPRRGIIPSSSPMNYRSSPADAARFNREVSSPLRQMSNTQSTQEDGDRTPRASGTALIGDSSPIRYEASSSPGRAYANDPQTNIPSDSSGLFVRSSRSQGPGSAVNNSRRGDITSDNLNTPNARRRIFMDESGRIIRDVPPEDAEAPSFSNLDPTTSDAQAMGGNSTLCIWGTNVSINDTLSTFKDFLRNYTKKYRMWGEGMSEEDTQADPESNAKEYLEMMQNMLTLGITSLNLDFRNLKAYPPTRKLWQQAQDYPQDIVTLMDQGIKDVMYEIAENQMAVQRQSQSSVGQTSGRSRIQSSEPPVPSSERSEAEAATPRAQDSNELDLCAEVQKRSYRVRPFGLDNTINMRDLNPSDVDKIIAIKGLVIRTTPIIPDMKDAFFKCSVCNHTVKVDIDRGKIAEPTECPRPVCGSPNSMQIVHNRSGFMDKQVIKLQETPDSVPAGQTPHSVSIRDYGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KD10</accession>
    <name>A0A5N6KD10_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H/ACA ribonucleoprotein complex non-core subunit NAF1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Nuclear assembly factor 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_003142</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KD10"/>
    <dbReference type="OrthoDB" id="21550at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000493">
        <property type="term" value="P:box H/ACA snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.230:FF:000002">
        <property type="entry name" value="H/ACA ribonucleoprotein complex non-core subunit NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040309">
        <property type="entry name" value="Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633">
        <property type="entry name" value="H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633:SF1">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="154"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="154"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="324"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="387"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00076743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8301255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="415" mass="44727" checksum="7D9A3AC149F66464" modified="2020-04-22" version="1">MEGDGGSDDEGTSKGAKGAGAQLRTKNEVPEEIIPKPDVTITPEMSITELGKVQGIVDNIVLIKAFTTGEYRVLREESVLCLEDRSVVGVVSETLGRVEQPLYCVRFTNAEAIAEAGLSVGTTVSYSEQHSTYVFTQALKAYKGTDASNLYDEEVGDEEMEFSDDEKEAEHKRKIKQKKAERRGGKVQQNGSHSHGGHSAQQPHNPGSNSAVLNYDEAEDGPYKTLSRPTGFTGGAGGGEAPQEGSHYNRPSHRGDNGVRGRGRGRGDRGRGDRGRGRGRGGGNNDRNNSHPRGTPSNLNPGVSNPQPHSLPQKPNFPPPPPASNIYNSPNQPQYPSQQAPLWPMYPQSYQPPFQQPQQPFPPVQNSWPGMSPPPTIPAGAFINPAFFNQQNGASQKGANPWTHPGEQHGNGGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KD27</accession>
    <name>A0A5N6KD27_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcium-binding protein NCS-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_003233</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the recoverin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KD27"/>
    <dbReference type="OrthoDB" id="202840at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000009">
        <property type="entry name" value="Visinin-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF178">
        <property type="entry name" value="NEUROCALCIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="144"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00071944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8301353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="252" mass="28314" checksum="8A2741F5B2B088CB" modified="2020-04-22" version="1">MGKSQSKLSAEQITELQKSTHFDKKELQQWYKGFLKDCPTGMLTKEEFQKIYRQFFPFGDPSSFADYVFNVFDSDKSGSIDFKEFICALSVTSRGKMEDKLDWAFQLYDIDGDGKISYEEMLAIVEAIYKMVGSMVKLPPDEDTPEKRVKKIFRMMDKDENGSLDMEEFKEGSKRDETIVSALSLYDGLISESRPGGPPGPPSMYFGSFVPPSSPIMGGLCFWKEVFVDSLSVAYGTGKLSPGLDPKDGSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KD28</accession>
    <name>A0A5N6KD28_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Linalool dehydratase/isomerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KD28"/>
    <dbReference type="OrthoDB" id="2580323at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40616">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40616:SF1">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025045527" description="Linalool dehydratase/isomerase domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="55453" checksum="E7103411741BC2C6" modified="2020-04-22" version="1">MSFSRVATAFLAASATARAGSYVTSLPYNAQGLFNESMDYLDRSYDNSAGYLYDTSGSTALRHETRTSAWYAIGLLARNQGSDIFEAEKIISNVINAQFKDAEDQWYGDYQIEPEEPELGSSNYAPVMYNSWDPNWRGFIGTAFIIGLEEFASLISPEVTSLMLKSLHNATLGDDYRVGGVDGDNLYPAYTNPSLMRAFVSGWTGRRLNDSNMTISGENYAQQIIDLFDRANTLSEFNSGTYTGVSLFAMTLWAKYLPEDSIMKQKGASMIQYTWEAVSNLWHPQLLNVAGPWDRAYGFDMTKYLSLLALHIWSAIGKDKSSIIDRPYIMSHNADFAYGPLFAILAEFHNSLIPDDVKDVLEHFKGGPAKNQRTFNPALIQWNTGNGIGWLTLYATEKHVIAEAAPGSLNLTYPEGNDTSIFTFLVSPFAAKKTISRLEDIQGLNLTVSGSTDKNFTLSYAGQYGGTDATINDFEYWNVTFAMPAGSAETPHIFLEAGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KD80</accession>
    <name>A0A5N6KD80_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_003279</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclease type I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KD80"/>
    <dbReference type="OrthoDB" id="441446at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF26">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8301409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="230" mass="25372" checksum="C3E45140AFA5F19E" modified="2020-04-22" version="1">MSQFPLPTLEPIKSPFPLFHMPFPRRMGHPHKTDTSQAVSPIMFIGDIHQPLHDENLDVGGNTISVTYAGKTTNLHAVWDTSIPEQYVGGYSLADAKSWAATLTTAIKTGTYSSLKAGWTEDIDIDDPITSSLTWASDTNAYVCSTVLKDGVAAVETGDLSTNGYYTAAIPVVKLQIAKAGYRLAACEHERKKERKNKKSEALNSYQKHLLHNSYILSELSQIKTLLYLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KD81</accession>
    <name>A0A5N6KD81_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KD81"/>
    <dbReference type="OrthoDB" id="5333304at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="196" mass="23233" checksum="524032F3CE038397" modified="2020-04-22" version="1">MSTRPPVETFEEDGVLYRRASPVAVPRRVITQPEYAHPEYRSYREREYSARPTPMRPPGEEYVRVRAQPERRQVSHFEEAPREYISRPQSVRPDAIRYEVPREYVGRLSSVRPEAPLREYASSVHPEARREVMAPPRREFSVRPTEIVPRSHQPIMAEGERYYEVDNQRPAIIERPREREGSVFIYADDAPRKVYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KEU0</accession>
    <name>A0A5N6KEU0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Involucrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5365701at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053268">
        <property type="entry name" value="Woronin_anchor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40641:SF2">
        <property type="entry name" value="INVOLUCRIN REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40641">
        <property type="entry name" value="INVOLUCRIN REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_2G08060)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="934"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1070"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1545"/>
            <end position="1960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1979"/>
            <end position="2123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2330"/>
            <end position="2584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2607"/>
            <end position="2774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2802"/>
            <end position="2856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2877"/>
            <end position="3181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3200"/>
            <end position="3231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3255"/>
            <end position="3382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3472"/>
            <end position="3503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3525"/>
            <end position="3562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3581"/>
            <end position="3758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3806"/>
            <end position="3828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3931"/>
            <end position="4119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="4228"/>
            <end position="4660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="4716"/>
            <end position="4751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="4965"/>
            <end position="5008"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="5082"/>
            <end position="5339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="5501"/>
            <end position="5535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="5544"/>
            <end position="5563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="5588"/>
            <end position="5701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="5744"/>
            <end position="5784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="5824"/>
            <end position="5913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="5986"/>
            <end position="6010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="6043"/>
            <end position="6189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="6280"/>
            <end position="6299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="6321"/>
            <end position="6393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="6415"/>
            <end position="6471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="6532"/>
            <end position="6551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="6999"/>
            <end position="7032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
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                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
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                <person name="Abate D."/>
                <person name="Pollastro S."/>
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                <person name="Faretra F."/>
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            <strain evidence="1 2">Mlax316</strain>
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    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KEV5"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="100" mass="11385" checksum="A67C9D5D70BB1D82" modified="2020-04-22" version="1">MNITYHWNNLLGYLSGKRNQLQVNRQVQLSKIPESAFKSFVRPFPLFNPIVPEFPVTSSHDVFANLHIMIPTNNHHKPIEIVCCARVIFAISCAIAQVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF50</accession>
    <name>A0A5N6KF50_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hcy-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_005827</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF50"/>
    <dbReference type="OrthoDB" id="261426at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="entry name" value="Homocysteine-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11103:SF10">
        <property type="entry name" value="HOMOCYSTEINE S-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11103">
        <property type="entry name" value="SLR1189 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="Homocysteine S-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Hcy-binding" evidence="4">
        <location>
            <begin position="1"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8302410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="265" mass="29506" checksum="FBCF841C6755ADFA" modified="2020-04-22" version="1">MRSAIDIASDAFSTQKDSNGKIALSLGAYGAIMTPGQEYTGKYDDEHKSSEQLSSWHHERISVFSRDSKCWERIDYVAFETIPLLEEIEGVRKSMGEVERLNGAEAGSKPFWITCVFPAEGYSLPDGSSVQQIVQAMLGKNDGSPIPFGIGLNCTKVGKVEVLIKDFEQSVDALVKSGEVSERPSLIVYPDGTTKGEVYNTTTKVWEIREPPGKDDLHWDEAVLEIVKGARERGFWREIIVGGCCKTTPREIGKLRERIDRLDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF54</accession>
    <name>A0A5N6KF54_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF54"/>
    <dbReference type="OrthoDB" id="5398396at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024908066" description="Secreted protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="17515" checksum="800A7130EA807704" modified="2020-04-22" version="1">MRVGQLGCEAFVWIVFVSSVLLSLTFSSSSKDVHGCGYRYHFGGISVAGYECKRFQLQTHFLIDQRRTFPCAPSFMIRWLLKPIHLHSVYLELANYHPLSNPSASSHITSMNRKPGSLHCHRINRIPHPLSLKRQPSTEPSLVNPSTQNISIALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF55</accession>
    <name>A0A5N6KF55_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF55"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="268" mass="30127" checksum="7A00D699DAADA73B" modified="2020-04-22" version="1">MREIQFTCTAFATVTVTVIVTAIVIVIAVIIAIYYYYSSSSSSSSSSSFFLINPKSLNITATATAAVATATAAATAAATATATATTTTTLITTKYYYYHHYHHSYLLPTHFRAFHFLSSSSNNQEINHLFLLLLLLHNILPYLRNQPTLIWIFGSCSSLTSQFPLRYAFVRSYHISLPPSPSFPPFHISPSGISISIRGIQERKERKAKKRKKRKRKKRDTIVYLHPIQSTIVKGSFHPSPIRFLSILNDKRKLKIAIFDKPLPPQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF60</accession>
    <name>A0A5N6KF60_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_005835</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF60"/>
    <dbReference type="OrthoDB" id="2593732at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF4">
        <property type="entry name" value="HYPOTHETICAL CONSERVED PROTEIN (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8302420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="141" mass="15555" checksum="591427EF86A0F9B9" modified="2020-04-22" version="1">MIASIPHGITDNQILWDPFLSTFEKITILADDVISNPAFTTTFFQIDMGVIGPLYNVAGACRHPIVRRKAIALLERVPSLQEGIWNAGMTARVARKVMELEESGIAEVREAADVPDWARISDVVPEFEKGGEASNVEVFNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF63</accession>
    <name>A0A5N6KF63_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PAP-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_005831</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF63"/>
    <dbReference type="OrthoDB" id="273917at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043634">
        <property type="term" value="P:polyadenylation-dependent ncRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045862">
        <property type="entry name" value="Trf4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092:SF15">
        <property type="entry name" value="INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092">
        <property type="entry name" value="POLY(A) RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAP-associated" evidence="3">
        <location>
            <begin position="54"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8302416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="189" mass="20898" checksum="8194F051353CA307" modified="2020-04-22" version="1">MPILVTIIKHLLAMRGLNEPVNGGIGGFSVTCLVVSLLQNMPQVKSGTMIPEHHLGEVLMEFFDLYGNEFNTSTTGISVNPPHLFSKSAARNVVYRDLHAQKFSIIDPNRADNDIAGGSSNTPAIQNCFSAAYTALQQSMNTLQHSNLESRRNQSLLRCIIGGNYESFRLQRDHLAHLHEELIGPIEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF71</accession>
    <name>A0A5N6KF71_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF71"/>
    <dbReference type="OrthoDB" id="2446291at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="192" mass="21336" checksum="97E2F8D57CF964AD" modified="2020-04-22" version="1">MHRQGENAFSSQMPEGPTYSDDFDMIDSTMHLSPGPFQPDTSLTLANRIPTPVHSSFSAYSRPDKPLHSTLSEPNLTDEAFIDQFPRGRRLPSPISEGEMSPSVIVEGINDMQMEVESSFPSPELEKEISTPHKKGHTRSKHSLRNWNGSTGDLAGNLNGVGTKRSFSMGYRADCEKCRNKVPGHFSHIITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF87</accession>
    <name>A0A5N6KF87_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WHI2-like protein P4H10.16c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF87"/>
    <dbReference type="OrthoDB" id="9451547at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035097">
        <property type="term" value="C:histone methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026638">
        <property type="entry name" value="NCOA6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15690">
        <property type="entry name" value="NUCLEAR RECEPTOR COACTIVATOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15690:SF0">
        <property type="entry name" value="NUCLEAR RECEPTOR COACTIVATOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="511" mass="56687" checksum="BC205A136ECFB440" modified="2020-04-22" version="1">MDQDQLLLQLHRQIQLNSAQLNSNPTNNQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQHQHQHQRQQVNPTTLSNTQGAIDGPSVGLDNITVEESGLKLQVEEELQQFQVDRTQSPPPRYPISEPSHPTPHSSPRPPPFSSLYNSTAEAVEAYNKVTVTEAGASLSTSTAAPEYAPVASDPYRQTHEASTSSRDVEAETKAALPQDTKGESPKKDDENEPPPAYSEGSSPLDSFTYLMAAAGGAASIITQVQQGAAPINTLGDVGADENITMDLRGTRFTLSRDELLTLPEFVLLSLFPNGLLPDGHLSTYHEGDAFQVDYDPASLQYMLEFFRNVAQTIPSGSNSPSTGPETDTIPIEPMAGSAREMLQDRAGIIALLKQDGIFSGLRRSEETGTTEQHLIEMLTAGGFNHDDHWGHRAGEPNKAVICSLALARLRTDIRGNEMGGNAVGMAQKLLLFWRKPARRCWWEGVELENVEGVEGKLKVWIRRVWTLEMSVIGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF88</accession>
    <name>A0A5N6KF88_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_005693</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF88"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032889">
        <property type="term" value="P:regulation of vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000550">
        <property type="entry name" value="Serine/threonine kinase 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000374">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052239">
        <property type="entry name" value="Ser/Thr-specific_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998:SF2">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="32"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="162"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="172"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8302251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="320" mass="35648" checksum="5048AC0A14B40877" modified="2020-04-22" version="1">MAQYFLDLLYTLTNCMSCFPGSPQLKINNRNFKILRLLGEGGFSYVYLVQDTSNDNMYAAKKIRCPFGQESVAQAMKEVEAYALFSPHPNIIHSVDYCVSADRSDPGAKTVYILLPYYRRGNLQDIINANLVNHTKFPEKRLMVLFLGVCSALKAMHNYKVKGGPGGAKSQDNAKKVRADAARADQEAEEEVESRRGRQRGREADPDSEQQEPLMDGEVTMSQEGIAPGGARAYAHRDIKPGNIMIDDDGVQPILMDLGSLAPSPTPITSRSLALAVQDQAAEHSTMPYRAPELFDVAHYMLAWWENRPLRCAATKREEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGX1</accession>
    <name>A0A5N6KGX1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Prenyltransferase alpha-alpha toroid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_006172</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGX1"/>
    <dbReference type="OrthoDB" id="24893at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF4">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="9">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8302831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="290" mass="32173" checksum="4513E38911EAA2CE" modified="2020-04-22" version="1">MRYCYVATAIRWMLTGDAHEERGDDDIDVEKLVGHLRAGQTYDGGISESAQHEAHAGYTYCAIASLSLLDRLPKRPSSQPTESPSSNPSLAGLTNLPETIRWLALRQTSYHEEAEENENGQEEVASDHHFVPNVDSTFVGFNGRCNKRVDTCYCFWVGASLNMLGFPNVINKDGSRRFLFEKTQHMIGGFGKTPGDPPDIYHSYLGLAALAVLKEPGIKELDSALCISLDAKKDIERLRKVALVPSRTYWVHGYSFKVREDSPEFGEKMAMDEGPPKGLIDAFEGVKITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGX3</accession>
    <name>A0A5N6KGX3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_006244</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGX3"/>
    <dbReference type="OrthoDB" id="193703at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.130.10">
        <property type="entry name" value="Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain (AZUL)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032353">
        <property type="entry name" value="AZUL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042556">
        <property type="entry name" value="AZUL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056012">
        <property type="entry name" value="DUF7590"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051986">
        <property type="entry name" value="Innate_Immune_Apopt_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16295:SF10">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16295">
        <property type="entry name" value="TRAF-TYPE ZINC FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16558">
        <property type="entry name" value="AZUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24503">
        <property type="entry name" value="DUF7590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23580">
        <property type="entry name" value="Znf_XAF1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7590" evidence="3">
        <location>
            <begin position="13"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-protein ligase E3A N-terminal zinc-binding" evidence="2">
        <location>
            <begin position="396"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8302925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="510" mass="56915" checksum="FF1834A1A69D684E" modified="2020-04-22" version="1">MAKAQKAPGTAQGSSIGGDLDIWKASQGQVAEGDYVDYTLPSWDRSHGLDIELSLEDDGDVELFISPQSAHQRAKPREDEHVLGDFSNNTTKRIVIESSNVELEGAEALLLSVYCRGSLAEPSHGPRTYSLRVKSLEKGASNGSSSNPVPIEEDTEMHGSDEEECKNCHQWVPKRTMMLHENFCLRNNISCPHCNNVFQKKSQEWQNHWHCPYDSTHGNSPESKTKHDSVFHESRQCPNCLYEATNLRDLATHRTSVCPGKIILCQFCHLEVPQEGDPFDPSPESLISGLTAHELADGARTTECHLCSKIVRLRDMSTHLKHHELEKNNRFKPDICRNINCGRTLDGVGKNGEVGAGSRMGQGPGNDLGLCSICFGPLYVSMHDPLGKAMKRRVERRYLSQLITGCGKRWCTNLYCKTARAKEAKVPQVALMAKDVLPQIQPLIAQMDDKTEPMYFCVDEGNQKRRNLAEMLAMEAGGWELEWCIAACEAEGANIDKVRTWLSNWAPRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGX9</accession>
    <name>A0A5N6KGX9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">EYC80_005896</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGX9"/>
    <dbReference type="OrthoDB" id="63989at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990604">
        <property type="term" value="C:IRE1-TRAF2-ASK1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070059">
        <property type="term" value="P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036498">
        <property type="term" value="P:IRE1-mediated unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10422">
        <property type="entry name" value="RNase_Ire1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.180:FF:000002">
        <property type="entry name" value="Serine/threonine-protein kinase/endoribonuclease IRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.180">
        <property type="entry name" value="KEN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045133">
        <property type="entry name" value="IRE1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010513">
        <property type="entry name" value="KEN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038357">
        <property type="entry name" value="KEN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954">
        <property type="entry name" value="IRE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954:SF6">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06479">
        <property type="entry name" value="Ribonuc_2-5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51392">
        <property type="entry name" value="KEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="KEN" evidence="16">
        <location>
            <begin position="167"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAB8302499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="302" mass="34397" checksum="52CCCAE87C540968" modified="2020-04-22" version="1">MGKNGKPRLLVSDFGLCKKLEVEQSSFKATTAHAAGTSGWRAPELLLDDDIKPGTMVDTSTDGGGSGSILVSSDVMPNRRATRAIDIFSLGLVFFYVLTKGSHPYDCGDRYMREVNIRKNNFNLDVLEILGDYAFEAKDLIGSMLGKEPKSRPTAAQVLAHPFFWSAKKRLNFLCDVSDHFEKEKRDPPSPPLLELERWAPDVCHGDFLKPLGKEFVDSMGKQRKYTGTRLLDLLRALRNKKNHYEDMPDKLKKDVGPLPDGYLSFWTRKFPNLLIICWNVVYELEWDHVDRFKEYYEPDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGY8</accession>
    <name>A0A5N6KGY8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_006238</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGY8"/>
    <dbReference type="OrthoDB" id="9974981at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF1">
        <property type="entry name" value="CIPA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="7"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8302918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="289" mass="31832" checksum="FADB5FCA93FBB928" modified="2020-04-22" version="1">MPFDMIKKVALAGASGPVGEAILAELLKSELFDITILTRDSTTHQSLFPPAVKVIQVDYTSLPSLTHALSDQDALVSAISPTAIPAQKLLIDACIQAHVHRFLPSEYSYDFYSPRIRAHPTPLSSSKISIEEYLQAQATQTSLSYTLLFCNPILELSLKNNLFFHFANRTAILNPQTSHAPISLTTLPSLGKAVRRILTHPRETANRPIRIKDIDISHQRLLSIAQSLTPGQEWNIHAEAESPSEADFAFGGKYERVHNSVFGIKEMTVADLEDLVRVTLGGAEKGDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGY9</accession>
    <name>A0A5N6KGY9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_005901</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGY9"/>
    <dbReference type="OrthoDB" id="446113at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12611">
        <property type="entry name" value="RRM1_NGR1_NAM8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12613">
        <property type="entry name" value="RRM2_NGR1_NAM8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12346">
        <property type="entry name" value="RRM3_NGR1_NAM8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000065">
        <property type="entry name" value="mRNA binding post-transcriptional regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000222">
        <property type="entry name" value="mRNA binding post-transcriptional regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000227">
        <property type="entry name" value="mRNA binding post-transcriptional regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050825">
        <property type="entry name" value="RBM42_RBP45_47-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640:SF10">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="72"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="164"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="300"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8302509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="450" mass="48060" checksum="63840B28E6C9F2F9" modified="2020-04-22" version="1">MSFQQQNYDPAQQGGYEQNNGNGAMPPPAMQQQQQQQQGGIPAGDSGSPAPFAQQGAGVEGSSGSVAGDAKTTLWMGELEPWIDENFIRSVWFGMGEQVNVKMIRDKFSGNAGYCFIDFSSPAAAAKALSLNGSMIPNTSRPFKLNWASGGGLADRRDDRGPEFSIFVGDLGPEVNEYVLVSLFQARFPSCKSAKIMTDPISGMSRGYGFVRFAEEGDQQRALTDMQGVFCGNRPMRISTATPKNKSGGAGPAGMQMQGGGIPGAMGGAPGMYGMGGGPPMAGYYGAPQPMNQFTDPNNTTVFVGGLSGYVTEDELRSFFQGFGEITYVKIPPGKGCGFVQFVQRHAAEMAINQMQGYPIGNSRVRLSWGRSQNNSGPAGTPYRPAPPPPHYQQMGMPQQHNPYGAFQPLQQKSSFANGVKCCMASFCTGLAIFRASLLRVQCLDNCFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGZ3</accession>
    <name>A0A5N6KGZ3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_006186</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGZ3"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054295">
        <property type="entry name" value="CHS4-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF16">
        <property type="entry name" value="CHITIN SYNTHASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22997">
        <property type="entry name" value="CHS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="506"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase 4-like" evidence="12">
        <location>
            <begin position="409"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="565"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="604"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="570"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="616"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8302851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1018" mass="112690" checksum="EAFCB982A49519AA" modified="2020-04-22" version="1">MSPPRRPDHSEPHRSNIYRNNSRRARAQDEEITYYTLPAASPTHESHPSKSSFGDTASSPLTPTMSREPISPSRTTTPATGMSRKRSLIRPERRRIDENHPNYHYRQHAANMDTQPSTTGNDSLMEDIEADAANTETSGLRTSGDAESDITPPVKRPTRGHGAGPDDPTSNEKAGFASKSRGGKKLRRERVQKMSPEEKARQKALDTVKPPSLWNVYCAIITFWCPGFVLKCFGFRSKAQQRAWREKMGLISIILCIMACVGFLTFGFTAAVCGNGGGLRLQVNHVDSGYMIFHGRAYDLSKSSHPAATGIASGSNVLYDLPQKYGGMDGSFLFQNVNGKCKGLITLADGSDVPTNSDKDLAWYFPCHAFNQDGSSSPNETVGPYFGYACHLQAEARNSFYDLRNAGDVYFTWDDIKNSSRNLMVYSGNVLDLDLLKWFNTTQVSVPSRFNVLADTSSAANAAVRGRDVTHAFQSSEDKKIAQCFEQIIKVGSVDTETVGCIASKVVLYVSLVFILAIVLVKFVLALIFQWFIASKYAASKTSQSSDPKKRQQQIEEWSDDIYRAPPRMAGDIGSSAAGSGSDRTSKRASVFLPTTSRFSNPYAAADRSSRVGRPQPTTMASQNSTAQLIPPNPMFRNQDSSRNSLLRTDITNELDGHGPASFISEHVVPQPPKEWEPYGFPLAHAILLVTAYSEGELGIRTTLDSIATTDYPNSHKTILVICDGIIKGEGEPRSTPEVVLGMMKDFVIPPDEVPAFSYVAVERGSKRHNMAKVYAGFYDYGADSTINVNRQLRVPMVCIVKCGTPDEATHRKPGNRGKRDSQIILMSFLQKVMFDERMTELEFEIFNGFYQISGIFPDMYEVVLMVDADTKVFPDSLTHMVSAMVKDPEIMGLCGETKIANKRASFTSAIQVFEYFISHHSVKSFESIFGGVTCLPGCFSMYRIKAPKGGNYWVPILANPDVVEHYSDNVVDTLHKKNLLLLGEDRYLSTLMLRTFPKRKQVFVPQAVYGSTVLSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KH91</accession>
    <name>A0A5N6KH91_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_004602</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17919">
        <property type="entry name" value="DEXHc_Snf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056616">
        <property type="entry name" value="Chromo_MIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055565">
        <property type="entry name" value="DUF7141"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041684">
        <property type="entry name" value="Znf-PHD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF17">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23615">
        <property type="entry name" value="Chromo_MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23614">
        <property type="entry name" value="DUF7141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15446">
        <property type="entry name" value="zf-PHD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="744"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="1051"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="167"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1310"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1494"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1697"/>
            <end position="1770"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1617"/>
            <end position="1648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="231"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="299"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1501"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1750"/>
            <end position="1766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8303153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1839" mass="207979" checksum="66F74ABA4BD3D9E8" modified="2020-04-22" version="1">MARLSHIVSSSESESEPGKSPQSEDLHQSTAKANRRSKSVSAHRFEESVQKQEPDQEGENDPDNTIVVMVPVPKNPKEFVPYTDDTVTSVLEELTGNDGEILYRVAFEDERQENVTFNRLLHLPNGKNSLDIFNGGESSESVAVDRAGKRARYPPSNKDMVDFTNFDLRSEDDNPKKRGRKQRIVKDLSTADIKKARRSTRVGSLKPSRLVHDDDDEDGSESEVFLANTHQSRRAARPLRKAAPRRANESLNYTEEDEDELAGNGQVESEGSEIAYAPNKSRGNITSAPPSKSRPSRTSGRENKTGKNMKERDIDEELFADEPMENGVAKVVSIREIYQPIPAKSPFGSVHDQDCDVCGGSGNASNKGPSDLIYCQGCSSSIHKLCLGYRAGREHIVTKVGHEHFVMQCRRCINLANKKDPMAPKLGTCSSCHEPGLSCAAFSPKKTAKQEEKLREENNGDDPITAVRADFINNPANVLFRCRGCHRGFHFDHLPPFQKGSSSSKNAKDLRAQRFDEYTKDWQCKECSQTTTKLQTLVAWRPIDRNSYNEGDDYDDFREDQKEYLIKWDDKSYFKCSWMPGSWVWGTAAASMRKAFRRRDEGANRWPIWTEEEAVSEEYLRMEIVFDVEYEDSFQPKSEEHDKAHIASVVQVLVKFRGLTYDESVWEEPPSPNDADRWSDFVSAYNEYVMGKYFKQSPAGAVKQRLDAFRSLNFQKEVFLKKQPDSLTGGEMMQHQMEGLNWLLYNFHQKKNVILADEMGLGKTIQVISLIASLVKDKPKCSPFLIVTPNSTCPNWRREIKKWAPGLRVVAYYGARSARDMAMKYEMYPNGCSHLCAHVVITSFEAPVDDSSRAFFKKVKWAGMIVDEGQRLKNDGNLLYTALTALRVPFQVLLTGTPLQNNKRELFNLLQFLDGKLDAAQLDVDYNELTKENLPTLHNLIRPFFLRRTKLEVLKFLPPMAQTIIPISMSVVQKQLYKSILAKNPELINSIIGKTSKTLKPTERGNLNNILMQLRKCLCHPFLYSSAIEERALPPEALHRNLIDASSKFQLLEIMLPKLQARGHRVLIFSQFLKQLDLVEDFLNGLNLPFQRLDGTISTLEKQKRIDAFNAPNSKLFAFLLSTRAGGTGINMASADTVIIMDPDFNPHQDQQALARAHRIGQTKKVLVFQLVTKDSAEEQIVQVGRKKMALDHALIESMGVDDDAGSNLEEILRHGAEAVLLDDNSKDIHYDSASVDEFLDRSQVENPATNDDDTVKSQFSHARVWIKDKGDLSDDFGDSDDKPAAPGAEVWEAILKQRAEDTAIEAAKNMQTFGRGKRARQTVEYNKSQPELNELDDPEDSPPRNGRRTRNGHSDDEFDGPGAKESEAEDSDTTEPLDPKDLKAEYFDWRQEDTYNKGIFPNLLAVQNWNDRGERLFEKCNRQIQESKGLDKNKSNANMEIENMQRLIRSRIDEPHWWHDQKKEEPTLFSRIPLSLPQPLAPKRRFEDAQMQDNGEEHMQNPSKKLKTANSQAVQPDARIIEQVEKHFRWLARKTLTRPLGDNGGRYPHPLSEFLTQLSLRLKKTTRLADDFEEHFRIQRPRDVLREHQDKAYKRRLAARQAVDTWTPIENHAPHIQNLDRRLQDTVEQLRQEIMQASQQLMLFQHRGLADSAQRLMPQPLPEGTASAVMQEHLRTMSRQLVGAIVPMSSSGLATLSGPVGSSMPLEQHSGGPIELDSDSEVPMRSSPSNRAIPSIEIPVKSKLGRPSGSMTSRPAVSSSYQSHPATPIPSSRIGPNACPECNSLYLKLVPECPCKASVVKIRYMIDNLNGIKNDPQQVAEAKKLLNAALASKLVLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHA8</accession>
    <name>A0A5N6KHA8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_006282</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHA8"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001471">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF288">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="13"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="330"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="581"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="619"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8302971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="640" mass="69876" checksum="6E908A3FA3F18A45" modified="2020-04-22" version="1">MLDERERIILSSGFFAAFIVAAATPAFSVIFARLLDTFYQTDNRSSNAIKWSLALLGVAIIDGTASFCSHYALEHAGQAWVSALRVEALKRILSQPKPWFEESTNSPGRLNEILDRNSEEMRNLVGRFVGIVFTAFFMLLISLIWAFVNTWKLTLVSMACGPVIYAFTKLFNRVSGKWENKCNYASEMTTSIFSETFSNIKVVRAFTLEAYFQEKHTKATQELYKVGRTRANYSGMLWGLTDAMTFFTTATIFYYATVLITKNEISVSTALQTVNLLLFGISNSTNLLAMVPQINSSRVTATHMLGLANLDPSSSHENKGTERLPSIFPINFNHLSFTYPARPETRTLSSISLSIAPNSTTALVGPSGSGKSTIAALLIGLYPPDTSVPPPLTFNQVSITNCHIPSLRASISLVPQTPILFPATILHNIIYGLSESSSFANISSAITAAKDAGIHDFITSLPQSYNTTVGDGGQELSGGQAQRIVIARALVRKPKLLILDEATSGLDGGSAEVVRETVQRLKKREGMATLVVSHTVGMMKIAERVVVMEEGKIVDSGGFEELKNRVAGKFAALIGEGLGNNKTMEEQNDIGEGSSKAVSTANRGSGLGISIPGYEDEMDNVRDTPIRDGRRRETWLRPDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJC5</accession>
    <name>A0A5N6KJC5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_005259</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJC5"/>
    <dbReference type="OrthoDB" id="309640at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00448">
        <property type="entry name" value="YjgF_YER057c_UK114_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.40:FF:000001">
        <property type="entry name" value="L-PSP family endoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019897">
        <property type="entry name" value="RidA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00004">
        <property type="entry name" value="Rid family detoxifying hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803:SF58">
        <property type="entry name" value="PROTEIN HMF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01094">
        <property type="entry name" value="UPF0076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="7">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8303893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="180" mass="19849" checksum="12BF6F8CB23084E4" modified="2020-04-22" version="1">MQSWTASNSWAFAASKPRTYKPKTLSQSFLKGDWNCPECGFHNFASRDQCKCGQPRKPTRPINSKKLPAPIGPYSHAMTTPTAVYVSGQLPVDLDGNLVEGTISEKTGTVLQNLSEVLSAAGSSLEKVFKVQVFLTDMKDLAEMNEEYEKWIKHKPARSCVAVKELPKGVDIEIECIATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJD5</accession>
    <name>A0A5N6KJD5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Alpha-galactosidase</fullName>
            <ecNumber evidence="4 8">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_005267</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="4 8"/>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJD5"/>
    <dbReference type="OrthoDB" id="5795902at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000286">
        <property type="entry name" value="Alpha-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000111">
        <property type="entry name" value="Glyco_hydro_27/36_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452:SF75">
        <property type="entry name" value="ALPHA-GALACTOSIDASE MEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00512">
        <property type="entry name" value="ALPHA_GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Alpha galactosidase C-terminal" evidence="10">
        <location>
            <begin position="344"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8303903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="432" mass="47991" checksum="7B555A0307F1FC38" modified="2020-04-22" version="1">MSTSSSFQLPPTTTSPTASESSPGPEAPVTSPLSNGLALTPPMGWSSWNQFGDLIDETLIKSTIDAMTSNGLKDAGYIYVNLDDGWQRHKGNRSNHPLEVDPVKFPNGMKALADYAHDKGFKLGIYSGPGDITCAGYTGSLGHEEEDAAMFAEWGIDHLKYDSCCSHADAPKSVVQKIVLKMSRALLASGRSIVYHACHCGWADIWEWAADEGANQWRIGQDISDDFNYPGNREKYYFDVLDMIDRGNDLVQYSGPGHWNDYDMLIIGLNGNSTQLVGTGASNIEYRTHFSMWAMVASPLLIGSDVRTLDTYELQTLTNKEVIEISQDPLGISAQTVGVGYEMDGDLQVYAKEMSDGSYAVALLNRGTFTAEMSLSPRRDLLMTWDHYRIRDLWKHKEGLYDVPYTVEVMPHEAKILRIWEVQANASMCFFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJE7</accession>
    <name>A0A5N6KJE7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005279</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJE7"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="159" mass="17907" checksum="3E2DE89D37FC2F55" modified="2020-04-22" version="1">MPCHAIPYHVVLHHLSHGHTAAFNVLEKRRGYTTLRTRMAVKLYRQVQQVFSCNGIYIEMRGYDKRDDCPVLQSIHTLRGRRLQSKSTIVAREAINVPRYVSTVIGSTPLGVKVSTTPYKTACAHSFKLDRNAVFLVCPCMKLPMISSASKMCNPRSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLA5</accession>
    <name>A0A5N6KLA5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003939</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLA5"/>
    <dbReference type="OrthoDB" id="5413827at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8304556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="43319" checksum="CB9D0EAC2C1DC2F4" modified="2020-04-22" version="1">MASLQIDDENDDLSQFTTSFRADSHSHNTWGLPGSTTIVATKRKRKTATFNLSPGLGLKHASHGACLSNCLPSPCSLKTTPELVEFNCPIRSPLLRYPLEVRERIYGYFLRSPKPIIMNYDWKAIRRCPNFTINKILFICKQITAEALSFLYKNNTFYALLRESKSLPDWGISKIPFTYLNLIKNVILECPKDNWDLNWYHTAAKSIRTLALAKPVLNTLAIVMSPQQVQLSSAALGLEAAPITFADFLWEDGEVFAAIMKLGCKNLKVVMKKDDGRRLMLEVAVNRIFTTSDDQNDWLKKDMPYQQGRENLKKEIKVELAALKDKFEQIFNDEKAVAMGWCRVMGRDERLVKDQRRQSNREMSAKLLKYRFGSECSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLB0</accession>
    <name>A0A5N6KLB0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLB0"/>
    <dbReference type="OrthoDB" id="3539294at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="327" mass="36791" checksum="F012764700ECF27F" modified="2020-04-22" version="1">MATVSKAFETLQAGKKAFKQGKDIHGKVMELHGNIQEVIPLSKDIPKNRVKFLQAGKTAIKQRHEIHGKARELHGQVMDVHGQVMGIQGQFQEAKQQTPENASNFKNERKGYARGCLCGCWAILKAEAKKYFTYVFSLIIFAIITIGLICFFIPVLWHHEHLQLLTLKTKAKVPGVTRRGNLNLTDENIDYRIYLLHYCVSGLTAQAGKQFNMENGCHHSTQALYDHILPAISTTFTPSLAAKDVLGPSMDIQALFKHYGYISFYLYIFDIILMPIVAGGFIWWFISTLKPWKRIFRAFLCPPASTSSRNQIYSTYSASTSPGVSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLC0</accession>
    <name>A0A5N6KLC0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_003875</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLC0"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF47">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8304485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="45791" checksum="3834D5B7E4CFB454" modified="2020-04-22" version="1">MPMQLITTLSNLPNSVIYSDIQENLTPRIQTVDALSNVSNILRIHDTTAYEIYQDVQTNIHAYREQAQLPGDELETEAEIKPGWVLDKYKFLPMLEHAQKNYPGFKWTVYIEDDTFVFWTNLLRWLATLSTDDKPFYYGAHSGGNNETFAQGGSGIVFSRSLMKSVFSGPNIPTLKEYANFTADACCGDMILGKVLRDHNVLVNQGEYGPVSFRPEPPWKTTFEEFNWCKPIFTFHHLHQRDLVQLTMLESKINQNNLGSQRPIIFRDIFLATVSPYLKDRLDNWDNFASRHKLTEKITKITNPPWAPPPDPVVQDTAALEQAYTSPEACRAACVALPDCRIWKHEIDKQKQKSCSLDIVVILGREYLGGPPSNRKTVTSGWMMDRINGSLMKDKCEVVAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLD4</accession>
    <name>A0A5N6KLD4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLD4"/>
    <dbReference type="OrthoDB" id="3552036at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="208" mass="23914" checksum="D032626EDE943849" modified="2020-04-22" version="1">MKRPTRMDSEARDVNSTPSNYFELVGANTPIQCPPRAPSPPINRDLPPPPRLERLPTPDFEDSCYDRPKFCECLGCYEVESRRETLAYSKIEDQYKAAMAYIKDARPVSRQQRQDPAIVSTEDSRVYNLMHIGYPRIIAAVSSEDCSYDFEKSRVPLYNISNRSFNPSTPPSHRQASSLLTPISQIKYFTINFNIDINFSIINFEINY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLD6</accession>
    <name>A0A5N6KLD6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLD6"/>
    <dbReference type="OrthoDB" id="5062908at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059009">
        <property type="entry name" value="Znf_C2H2_17_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059095">
        <property type="entry name" value="Znf_C2H2_17_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26177">
        <property type="entry name" value="zf_C2H2_17_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26176">
        <property type="entry name" value="zf_C2H2_17_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="398"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="434"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="669" mass="73864" checksum="2E8E2001CA6E8FFA" modified="2020-04-22" version="1">MTCTETLTILPETMAGFDTQSHSRKASASGFHSRTPFQGTTGFSLRHTEPAQGQYSGISWNGKSEGLQYSPRGSTSQGSNGFSDSLYIPIAQMPSQRWSTDLTSGLESVEMTRFPSQESSRTIQSTSTSECALPMGYFPNASQAPYQISSARSDTSGRSASPANSGLYTPTVQYDLPSAFDTFQYPGDELAEHDYQVPATSGFQQPPTLSLTTGGFDMFSSAHGLPTSMTATPSTIASYIHSAQDSVLFDSSIMGSPEMWDAALLESSKPQTPIAEEWTLPPQMMSSTNSPLDYSPTEGRSPRIIRKPMGPRASKVASDTNARRVPGTEMPEESFKLMGRSSLDADNSARDHQLYHNVTTQSDGLYHCPWEGTSACQHKPEKLKCNYDKFVDSHLKPYRCKVPACADNKFSSTACLLRHEREAHAMHGHGDKPFLCKYDGCERGVTGNGFPRRWNLYDHMKRVHNDPCTSRSAGGSPPPTEKPATGSKKRKQDAITEPSTSDKEPVKRAKTPPVVNQQPSFAEIYHQSEKRLQEAVKQLHDLESANAMTNLRNASDCIKAMAQALQKMNQAPGMSRLFISTLSRHVSIKVSRQGYITAEPARSDDPVRKSHDTKKKFDRIKVMEPVMHIYISQDQGASHKEFFCMSRPRIVNFQESTVPVCLFELHTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLG9</accession>
    <name>A0A5N6KLG9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLG9"/>
    <dbReference type="OrthoDB" id="18170at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="103" mass="11597" checksum="525EA4F364132E26" modified="2020-04-22" version="1">MAVRHQFHIRELLGVLGIAQVTILLGLGRELGAGSWYSYIGPPLFNIAMLFRMITAIDFRSPEQCRWWFGHGPLMAGNVMVASLCIEYLRRIDTNIWVSTGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLH9</accession>
    <name>A0A5N6KLH9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_004022</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLH9"/>
    <dbReference type="OrthoDB" id="19092at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="293"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="57"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="227"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="367"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="435"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="459"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="476"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8304653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="524" mass="56629" checksum="D623320CEA7CDF1A" modified="2020-04-22" version="1">MAAVISPTTSPATSPPPNRLSQYSNYSAPSRSRPPSHIFPVFHSSLSYTTVRDFAYPSLHPMHYGPPPEPSQPPSGLSTPASESHKRLSDPPTSWDSRGSWGPGPWGGDGFMKGEQLAPIHFGDGPPWSEDEDLQSPVVVSSRHRKHKSSAGEYGGHSRGRGRAPRDGERRTSMLSQENFDDDGGYFAGTSGDNSERYYVNEGDEPDGPEGEYVTYPSELARRSMLAPYNVPGQRDSHFAGLLPSRSYTDESGQDYRSESDASSTVSSPGMTRHDESRYSRDYQFTIASPDEEMHGTAVALFDFERENENELPLVEGQVIWVSYRHGQGWLVAEDPKTQESGLVPEEYVRLLRDIQGGLNSLTGQVELASPVGGDSGTPTQAEHSQAFGHNPSSSNGSNGYQQPVVSTFSTSSKDLHLYPQHLLGTQAGQAPPQIIHYHGQRGGSQANTPTIPSSLEGLIDRPSSRDAKNGKSEDTSSNNETSVESAQTDSEPKLSSSTAVQKPGSPLGPSGDVASETHETPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLI3</accession>
    <name>A0A5N6KLI3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Chromatin modification-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_003932</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ING family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLI3"/>
    <dbReference type="OrthoDB" id="4173905at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15505">
        <property type="entry name" value="PHD_ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333:SF42">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12998">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Inhibitor of growth protein N-terminal histone-binding" evidence="11">
        <location>
            <begin position="62"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="10">
        <location>
            <begin position="629"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="111"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="217"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="268"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="530"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="395"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="438"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="454"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="540"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="629"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="640"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="644"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8304548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="720" mass="76186" checksum="BB1ADDD3610E39C7" modified="2020-04-22" version="1">MKTTKAPPSDPSSSRRAQPLRQTRNNPPRSSLPGSRPLGSRGSTGGSDGVPNADQTVEIFPAITQFADAISALPKELVRHFTLLKEVDAKVFGPEEELARLVDIALNTPPPTTTLNYPSNSRSASTNGNNHSASINGSLANGNGGPAGMVTEMQGESRHFQACASYMQNMLVSLDEKNHVISTASEALNKQLARLDQCFPYIEKEVSEEARYGSTTHWAYPENRTSKSNPGSSSRRDAPPTNTPSAIAQQQLADELAARSDARRQALLARKGAKAQHADSDFDDTQEGKKADSNKRPHGNSKARKAATAEASTSVGLGITNGNGTNGNPPKRRKVEKTTNAGPSAERSLNGVFAGNGTVSKGKAASPRSTPVPDGTKKPARARAAPNGQARKRNNTVNSAMSPSLASSPIRTTFPDIRPPVRASPAPTNGARPASARARQNSVQSIADTARRPPSSTSNKPNGNASGTPDLAAAASVTGKTVQEVKATMKEAGTNGKGEHLLEDAQPQNPEILGAIVVGHSKENMKREETVESNGDPMQGIQSTTVTTTKSGRASKPSTPAIPSFVEPVRSRSSRSVPDPVSTAKRSHKKGAGAAAQLIAQQNMELDDTTSSAQGDDEDAEIDADEPTYCYCNAVSYGEMVACDDLSCEKEWFHLDCVGLKVAPKGNAKWYCDDLGKLQQDNGVFRYGFDTLVAHSLQLYGAYRPIGVWISGVNLFGDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KNG6</accession>
    <name>A0A5N6KNG6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KNG6"/>
    <dbReference type="OrthoDB" id="497927at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47098:SF1">
        <property type="entry name" value="PFKB FAMILY CARBOHYDRATE KINASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_4G09500)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47098">
        <property type="entry name" value="PROTEIN MAK32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="1">
        <location>
            <begin position="199"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8305162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="411" mass="46283" checksum="7847CA1FF6953A97" modified="2020-04-22" version="1">MNQSLEKKASAVEIKQSRPLFTTLGMCILDDLYFPSGETKSRILGGSGVYSILGARLFSRNESAKRLSWLIRAGNAFPREINDRLQVWGTDLIVEKGEGDEVQCTRGELRYFRGENEERGGDVEFGSKTYRYITGPYRIEPRHLTLYPHLLHSSTYHFLTSPLDTLAQVPELLGLRYQPGIQTPPLIIWEPLPPTCKPSELENLMNAIAVVDIFSPNHIELANFFGLDMSTLVFSRYLIEELGNKVMEWGIVRDKKGTVVIRCGPDGCCVWYRKQSKWVWIEPYWTAEDKKRVVDATGAGNAFLGGFAVGWERSGGDEIVGCVFGSVSAGVVCEAIGVPILDRVGDVYGENSRETWNGVDVEKRLEEYWQRLVREGLVEGDLENLFWKQDLYGGISSPPALVHKEEEAITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KNL9</accession>
    <name>A0A5N6KNL9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_004062</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KNL9"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002402">
        <property type="entry name" value="Cyt_P450_E_grp-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00464">
        <property type="entry name" value="EP450II"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0843">Virulence</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8304699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="30644" checksum="400BB196E65FE731" modified="2020-04-22" version="1">MEYSTGTIMGYSTSSTALTIFISYVVYLVVGGLIHSQRLRIRAKKLNCQPPPILKNNLPLGIDQVTRALKALATKNFPPDTQKKHKEVNALTYITSVLGKDGFATIDEQNIKAMLGTQFPEFDLGAPRIDNFLPFLGPGIFAQDGKDWERSRALMRPQFARDNLSDLEMEERHFQVLLKALFEAGQDGWLGEVDIQPLLFRFTLDTATEFLLGQSVESQLAGIKTASGVKAEDTDIEAFGREFDIGNMALAKRSRFAPFSVSMIYSLVVNFDAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JMC7</accession>
    <name>A0A5N6JMC7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_010649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000022">
        <property type="protein sequence ID" value="KAB8289487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JMC7"/>
    <dbReference type="OrthoDB" id="3552806at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8289487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="481" mass="51604" checksum="54F546B276EDACF4" modified="2020-04-22" version="1">MRPRRDSTGNTNGFVRPVRKVAEAIEKKAAISDGANSENGEERTNEVTNENMTSGANTSGSPVGKKRSRRSKADPSNTFVRRSSRRVGGSVERIDDLVLNEVLGENKEEGSSSLSGSSLSDRVDVDTPTANTMNNASNAPSPVEQNIILGGNEQGVSVGGMDEVEDHGGSNGMIYSIVGHTIPRSPPAASDTIANIPNEARLSRPRIKLLLTPRASANKTNRHDPRRLSPKLLPAPSTPPKNTNFGPSSSLYLLPPSTPPNHMNNARRIAQVPFPPASTSWPSQFLAPAISSSNTNGTSFPPFPPPGTYAPMRTNGGPLSPYQEFMQSNVSSPRIGNGMPDSRSTGNAMTTTFPPPFNPFYPPTASYRSPYGPLFIPDAINQDRHGSNSTITAPDIDDVFNSRPQADGHGENEEMQESQAEVLPSANEILNSDPSELFEESLDLIEMATSTPKIGDRVRLAGEQSSPLYQGVSSDDMDWQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JMD8</accession>
    <name>A0A5N6JMD8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_010657</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000022">
        <property type="protein sequence ID" value="KAB8289496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JMD8"/>
    <dbReference type="OrthoDB" id="3598904at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF4">
        <property type="entry name" value="HYPOTHETICAL CONSERVED PROTEIN (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="34"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="296"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="341"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="387"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="341"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8289496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="790" mass="89352" checksum="0D46FC0BC7BA4CD0" modified="2020-04-22" version="1">MDTNPNRFERQSIQQDRPRPIKRARASKPKVKSGCITCKARRVKCDGTKKSKPQCLRCQKFGRTCDGYAHETPSRGSMMPIQPRIPTADFYTPSISLEATEEEGRYFRYFCDRTAYQLPGYFNPSFWNHIILQESHNVTSIRHAVIAIGALNKAIEEAPRPHLKVNVIQDINKKHLEFAVLQHLKAIQALNRYLSSVNGPQLRTALMACLLFVCFETIQGSYASSVQQTYGGLKLLRSYYAGKPGSKPWIPRRISGGLKRNPLTDKVIAKVHNRPGMDGSSKSETISSHIEEYLETETPTHQSALTPTVDRTATPPQRDYSPRLDKMPIPSHYRASLTLEQQRSLSGTPAQSYPSAYHTPSEYLSPNNHEHSDLAIPAFIASKNSSSHHSSSTIYTPESAHTPPSMGNTPPPTAYRSSQSPPILTNLRKRPIQSRSPTPPILQNDFTLEENIMQAFVRLDGQGLFFGMTPGIPPLIWDIHSAHHITIPRAFTSFCEAQHCWDFLMDRTLQYYRRTLFDRKFASTKSDTPSEIAQQYASYSARLNEFERAFEPILNSAISPQGEVLNQAAIVLITHLKATAITLSAVTSTSEMVYDSFMNDFRYIVGAAELLVTRSEVTPSAINSSRFSFDIGIVPPLHVVATKCREPNMRRKAVDLLFRSPRQEGMWDGVLSARIGRWIISCEEDGLDVPMRLETPYVQPDCHKQNFQYEQSPQSYDELLSPGYWSNSEIIPDIDILQENFAPYWSQTQISTPRTPSPFTQARTLPMKGRIAVPRQNDVWMVPENKRFHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JQK6</accession>
    <name>A0A5N6JQK6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TATA element modulatory factor 1 TATA binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_010691</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000022">
        <property type="protein sequence ID" value="KAB8289532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JQK6"/>
    <dbReference type="OrthoDB" id="74178at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052602">
        <property type="entry name" value="Growth_transcription_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022092">
        <property type="entry name" value="TMF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022091">
        <property type="entry name" value="TMF_TATA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46515:SF1">
        <property type="entry name" value="TATA ELEMENT MODULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46515">
        <property type="entry name" value="TATA ELEMENT MODULATORY FACTOR TMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12329">
        <property type="entry name" value="TMF_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12325">
        <property type="entry name" value="TMF_TATA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TATA element modulatory factor 1 TATA binding" evidence="6">
        <location>
            <begin position="769"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="27"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="645"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="325"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="532"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="782"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="152"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="667"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="709"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="745"/>
            <end position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8289532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="885" mass="97624" checksum="95241383397EC7FF" modified="2020-04-22" version="1">MTSPAKQTSSRWGSFLSQAVGGLESRLDNILAEGQEGPVNRPPSTTGTAVTAKPEAVSRSGSNSSRTNDRLQERLARAVAAKNAQKSGTQSASSNVPSRTGSPITVGESPRQSLDATSSVGGDEATKPISQDLESTATANTTETDTPTVEARSSTPVNDSSLDSHQALPSVTTLNAEPTTRLSTDSTRSNVPKGSVDSIQPPDPTSSSSTDEPPIIPTVSLPDAPVSSKTPAELEAALSQLQSDYETSELQRQEEVHGYIERIDTLQAKLQYLAKESLESASNAKNAAPPGSLEKKLAEKEQQVILLMEEGQVLSRKELTHMTAIKNLRAKIIEGNKEIAEAKKKQEKAEKEAASLAERLKRAEGAEKGLSERNNVINRLRKELDAIKIERDTKDTTIANLKAQLEDDAAQEKEAEARVAHEALEAEKKRVVELEDDISSLKIEKQLVNDRAQIQIKELREKMDREIENARIAALEMKNEQQMLESKLEVMRARAEEVSSGATGDAQAKLLRQVETLQTQYAVASENWQGIEASLTARARNLERERDEATKREAEIRRKAREVTLKAKRNEDELEETRSKLPNFQQELSERTAQLDDLKKRTEEAEAALVSAKAEFEEEKQTWNSELQQRILEEKQKWLEEISFGSRGESPVATSRKGLTSEYLGLQNMQSRRTSARSTTGEVSTPERLLGRRSAQPSSKYPDPGTPVRQDSTASLTNSISLNSIATNGTGERSDFKPQTPSLHTLDHDDFFENHRSSSPQQTIHDIISTSTAGAGPSVQLVERMSSAVRKLESEKVATKEEVSRLAAQRDEARAEIVNLMKEVEIKRELGERVKELEEEIKGIKERYEVTLELLGEKSEEVLELKGDVEDIKAMYKELVVRSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JR34</accession>
    <name>A0A5N6JR34_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_010944</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000017">
        <property type="protein sequence ID" value="KAB8290516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JR34"/>
    <dbReference type="OrthoDB" id="167718at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12400">
        <property type="entry name" value="RRM_Nop6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000376">
        <property type="entry name" value="Putative RNA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034228">
        <property type="entry name" value="Nop6_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF51">
        <property type="entry name" value="NUCLEOLAR PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="178"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="257"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="275"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8290516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="324" mass="35244" checksum="516F63186C0CEED4" modified="2020-04-22" version="1">MGFGAGASRAERKAKRRKLENSIPDIPDDLETESNNDSVLAKRKRALDDDANEGQIIDGNEEIAKKNKESNHKSKKNKTTAVDTTSLPVQNGELSDIAETELAPKKSKKERKAERKAREAAANATSNTQDTETAEKKNGPDTNTVGDSDQTTCTKKRAKNKKQGDGSGANAESKASRFIVFVGNLPFTATTASIKNHFAAVKPASVRHLTEKGNPTKSRGCAFLEFEGYDHMKTCLKQFHQTTFNDGLSAPRKVNVELTAGGGGNTKDRRSKIKGKNEKLNEQRVRQAQEADNSKVSKSKTTDVQHVLAEDSGIHPSRKARIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSQ3</accession>
    <name>A0A5N6JSQ3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_009997</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="domain">
        <text evidence="4">A pair of annexin repeats may form one binding site for calcium and phospholipid.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSQ3"/>
    <dbReference type="OrthoDB" id="37886at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018252">
        <property type="entry name" value="Annexin_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009117">
        <property type="entry name" value="ANX14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01813">
        <property type="entry name" value="ANNEXINFUNGI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00223">
        <property type="entry name" value="ANNEXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0041">Annexin</keyword>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0111">Calcium/phospholipid-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8291311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="469" mass="52451" checksum="DFD45BA0B55E1808" modified="2020-04-22" version="1">MSYQNYPPYGAPPAGLAPQSGYPPQIPPRHSPQVYQQYPPSHSPYPQSQPYGAPPQQPPYPPQQQPYPQYPPQHGSYPQHQPPYGAPPPGPPGQYPPLQQQPYSPQSGHPQQAYGAPPPAAQAPYGAPMSYGQATPPSPGYDPSLSSPPRIPYDGRADAQALRKAMKGFGTDEATLINVLHNKGPLQIEVLRQAFSDMFKRKLLADVESETRSYFREGLAAIIRGPLIQDCHLLYTGMDGIGTKEKYLTEVLMGRSNADINAIKSMYQRRYKRSLAGDLKGDLSMKTEDHFLMVLEANRNEDSAPVVPRDVDRDVAAIWNATEAIRGHEAKVVCEIFTKRNDAQLRAINHTYQQKHGKPLEWVIKKFSGHMEGALLHQLYTATDKAMRDAKLLEESMKGFGTKDKLLVARVIRCHWDPRHMEQVKGAYHHAYKRSLSSRIAADTSGDYERLMVKCVECSNLVQPGYSWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUV1</accession>
    <name>A0A5N6JUV1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUV1"/>
    <dbReference type="OrthoDB" id="3553727at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8292397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="21960" checksum="C7EB63E92AD70BC3" modified="2020-04-22" version="1">MSQSTFQNPMPLQDGKIPEDLLRQICEKLSHPNDLTKETSDQTEILRALLIQSTSNDSKFEFVWNAVLQSIAIIFAVVFGTFSVLAYLDPNAKSACAGLYQQPSEPLASLASVVFGSELPAATPTTTPTTTAGLNPSTFSSSSSIATSTATATPTSSPIGSKGDSGPSINGAAIAGLTVGSVLFVASVVSSIVAFRQKYYKERSSGLSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUZ1</accession>
    <name>A0A5N6JUZ1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUZ1"/>
    <dbReference type="OrthoDB" id="10252405at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045048">
        <property type="term" value="P:protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007317">
        <property type="entry name" value="GET4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04190">
        <property type="entry name" value="GET4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8291734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="76" mass="7873" checksum="6A5745C11C247B3A" modified="2020-04-22" version="1">MKKYAGQVKEAAGELWEEALVGVGEMYFGIQRPRQGNPLLDMMGSMFGGGMGGAGGQKQGAKRIGQTGAPVAEGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUZ2</accession>
    <name>A0A5N6JUZ2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_006517</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="4">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUZ2"/>
    <dbReference type="OrthoDB" id="4934715at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033609">
        <property type="term" value="P:oxalate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20305">
        <property type="entry name" value="cupin_OxDC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20304">
        <property type="entry name" value="cupin_OxDC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017774">
        <property type="entry name" value="Bicupin_oxalate_deCO2ase/Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03404">
        <property type="entry name" value="bicupin_oxalic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF49">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="243"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="6">
        <location>
            <begin position="808"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="6">
        <location>
            <begin position="982"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="568"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="573"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="1088"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="846"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="848"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="852"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="891"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1028"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1030"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1035"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1074"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8291720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1140" mass="126731" checksum="B0942E13673F28FA" modified="2020-04-22" version="1">MSQKKDTSATSSQAVPPDFHASAAEPSTPSWLNNSTPSESADSFGRVSIEDELPNYVGGAHWAAILENIAGLRDSLGSDEWPKGTARVNNKYKGPELLLGDNRKASRESILACLPSKPIVDDLIERYFTAIDASFITHAPTFRKEYAEFWANPNSKSISWIGFLFAIICLAAHFELKTGDVPISALSDMAVRDTEQRIGVYREKTVQCLITSNYTEPGLYTVETLVLYYLSEHFQSKDALFGSWMLLGMIIRAGMRLGIHRDASHYPNISIFRGEMQRRLWATITLLDVQTSCQVGLPRMISEGMYDTKPPNHLLDEDLDENMVVLPPDRPENVLSPITHALSKYRLLIVFGKIFDASNSIAPIPYDEVMKLEKLLFDAMEEVPKSFRVTSIQGLENGPVMLRVRRFSIEMAYLKARCFLHRKFLSEAKSLQIHSYSVKACVDSSMLILQYQSYMTSETAQGRSLHGMKWITSSLMTYDFLLAATLLCLYLGQMLAAEEQSMNTNLQDFPIEWTKENILCALLKSYHIWNNPENSSEDTMKFSKVLKAMLNKVGYWSTASKTQMEAAKEITSEDNSSRPSSYSIPNTYSLPQSNFEESPGDSSTSNIGMMEDILNDPTGLDWGLWDNNFQRSNTYIDTGSSLYASDSYFPFRAAGLGNNMKFYHWLGSRVQQKLHLTIWGNPTSNLIARAERSPRNNHLQNIRNIIAAPTGDPLLGFHPSNVVANQNTDAIDYELAPGQKDPATVGAYLDFTTVKNPQPIRGTKGGTDAGPRTEAYDILNPDKLAPPGTDHGNVNNAQWPMGLSHAKLGLGHAGWSRQQNVDNIPAATEMAGVNMRLEEGGYRELHWHKAAEWAYIFNGSVRLQAVNEDGQTFVDDLSAGDVWFFPPGIPHSLQGLKGGTEFLLIFDDGSFSEDNTFLVSEVFAHNPLEVLSKNFQLPESAWSNIPPGELFIFPGTKAPTDIAKQNITGSAGIVPQEFSYSYHLSKAPLTHDTPGGTIKILDPKTFPIAEKFSAAVVTVHPGAMREIHWHTSSDEWNFFIAGNARISIYAAQGTARTFDYHAGDCGYISKGMTHYVENVGKDDLVFIEVLQADHFSDISVGQWVGLTPKQIVADTLNLSDETVSAFKKEKQFIVQNDAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUZ9</accession>
    <name>A0A5N6JUZ9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thymocyte nuclear protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_007356</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8292994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUZ9"/>
    <dbReference type="OrthoDB" id="41445at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd21133">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.590.10:FF:000003">
        <property type="entry name" value="Thymocyte nuclear protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052181">
        <property type="entry name" value="5hmC_binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002740">
        <property type="entry name" value="EVE_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047197">
        <property type="entry name" value="THYN1-like_EVE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14087">
        <property type="entry name" value="THYMOCYTE NUCLEAR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14087:SF7">
        <property type="entry name" value="THYMOCYTE NUCLEAR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01878">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EVE" evidence="6">
        <location>
            <begin position="110"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="74"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8292994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="260" mass="29280" checksum="DB33795B5FFD4811" modified="2020-04-22" version="1">MVKRKAKEAGDDVVLVEPRRSVRQKTHNKESLKEDTTSLLTSSASKSKKNKKKARNDQPPNEAKVTGDIIAPRSNNSSTKSTKSTESSQLNGTKSTSTEISSEESTPTRQYWLMKAEPESRIERGHDIKFSIDDLAAKTEPEPWDGIRAYPARNNLRAMKKGDLAFFYHSSCKIPAIVGVMEIVEEHSPDLSAHDPKAPYYDPKSSPDDPKWSVVHVEFRQKLKTPITLKEIKAWFEEKGNALNNMQMLKLARLSVSKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JV42</accession>
    <name>A0A5N6JV42_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E3 ubiquitin-protein ligase listerin</fullName>
            <ecNumber evidence="1">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">RING-type E3 ubiquitin transferase listerin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_008122</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the ribosome quality control complex (RQC).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LTN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="1"/>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6108at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039795">
        <property type="entry name" value="LTN1/Rkr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054477">
        <property type="entry name" value="LTN1_E3_ligase_6th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054476">
        <property type="entry name" value="Ltn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054478">
        <property type="entry name" value="LTN1_UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057030">
        <property type="entry name" value="TPR_Rkr-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12389:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE LISTERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12389">
        <property type="entry name" value="ZINC FINGER PROTEIN 294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22958">
        <property type="entry name" value="Ltn1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22999">
        <property type="entry name" value="LTN1_E3_ligase_6th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23280">
        <property type="entry name" value="TPR_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23009">
        <property type="entry name" value="UBC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="E3 ubiquitin-protein ligase listerin N-terminal" evidence="2">
        <location>
            <begin position="46"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="E3 ubiquitin-protein ligase listerin tetratricopeptide repeats region" evidence="5">
        <location>
            <begin position="604"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="domain" description="E3 ubiquitin-protein ligase listerin HEAT repeat region" evidence="3">
        <location>
            <begin position="1253"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="domain" description="E3 ubiquitin-protein ligase listerin ubiquitin conjugating" evidence="4">
        <location>
            <begin position="1456"/>
            <end position="1538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8292386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1627" mass="182417" checksum="1F54A804FC4391B9" modified="2020-04-22" version="1">MGKRQFTSQASSARAATATAGFGFGFSTTSTRLSYLTEPSNLSSISDANVVVSFKNLSKKDGTTKSKALEDLRTFIQTQPNEQGGAEEAILEAWVNVYPRVAIDNSRRVRELSHSIQYELLKSARKRMEKYIPKIVGSWLAGTYDRDRAVARSAIDGLTSFLDTDAKMNLFWKRCQNEILDYAEEALNETPHTLSDERSVPIEDANEKYFRVNSASVSLLVNLLAKLSNDDILKYQERYEKVIFGNKKLWTLSSCEDASARKSTDRLLVLCLEKQTQLVENNLETISRAFISEALRSSQSTSALQLLQTLQELTTKFPEVWTSAYKGKHSATDDLKSFIRKGSQGSSPEYWQALRALVAILPISVLPQEPDSILEFLEAFRKSVNQREENKANASEAWLAYEETYKICIGYLSSSQQIEVVQKSIYPVFEHYLHPSSNTSEWLIRSNTPSSTLSSFISTLGKDANFKQSLDDEWQRLAQEFITRIQTSMPEQSKDYSSSQDAVIAEGHRWFSLLSAIFKLKDLTVDQNPLLQPSSNIIDISLQVIVNRNGKPYSAAALLEAALRYSPQLLETSPSTSEAINSFMETHLPKLVLSPSSSYLVSALDQFRSVPGQQSAYKSIWQEVIDGLLSAPKGSQQQKAIIALISSEDVADLVRDDQALQDYILETSSEVIKGNNEEWPLFEAAVGFNGFSKSTERLLLQNLTSALNVSNPSIDLVFQALELLSKARPEVVREGDAHVDLITKLLALTELSDPELGKRATSLRSLVDSTDNQNSVTTSSVVHILKENLENAGPQSLAINTLVQQAEAVIAASDDNSLHPELFPDVTKWSQSLAPLLVQAPNSTLGVMRPFAGAAFLVRSQENSEFSQPSRDVYGYSVALRMAMYSAHLVRDHPDRLSKDTLVEVLYLMCLTVELSNDQLDLLEINKLFAVPSEEAVSGVRAFGDMIYQETLPFILLHSKAWREGFESGSPLEFSSVVHTLIMKLLDASRGNTSTSFYSARVLSHLLPKLVEQHGWQAVGSEEWISKLEILKSSTPNILGAVAILTGLHETLSTSQLVSNLCNRIISDVAGATAQSEKTLGLIVLLNATLSIYDDDDLPVAQNRLVFAVKQILSWTPEIASTDYQLSSEACFALQRLLPAIKSVYGSYWESTLEFCIKIWETMESKEYYDQKLSMMGMSLKLFSNIRNLQDANDDLEDALTQYGETASQCFIKLMKLPRFKPTQPLGFVDNLLSRLVVKIPSSHIKDVSEFYPLSKREISVNALLEKKDAQLPEELLSLLLDAPSIRNFDDEELAEFPPSIRCYLLSWHLVYDSFSTASWKVRKDYCNHLQSENCIGPFLTFLFDVLGHSDGRPLKLEKAHFDESYIRSYDTTLADAETNERNLQWLLIHLYHLCLKHTGDLAKNWFSDCQSKQTRLAVEAWTEKYFTPILISDKLEEIEEWASSKEAKEGGEKELEIKASRGTRSVFASYEVDETSIQIAIRFPSNYPFYIVKVEGLNRVAVPENKWKSWLLIVQSAVAFSNGSLIDGLTTFRRNVEGSLKGHTECAICYSIISSDKKIPDKRCGTCTRFTPSPAYYNSTERSKQASTPPNINQAHFIQIRRIRCCAIKDIENLIVGLSYFLFTHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JV48</accession>
    <name>A0A5N6JV48_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007434</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JV48"/>
    <dbReference type="OrthoDB" id="190105at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8293074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="130" mass="14692" checksum="2978FB8E1363E33B" modified="2020-04-22" version="1">MSEIEVQLWKSPENLHDETRILSASDAVVTALHITKFHILTALDSGVLYIFSHKDGRDIGKELVVRIRERGIWCVGSWEGSEGDEREEWIVVGGTGSEDNLAIWGWNERGRFPNLSHMIASEPCELIFCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JV52</accession>
    <name>A0A5N6JV52_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_008138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JV52"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8292406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="174" mass="19992" checksum="0E5DD41F817A6A8E" modified="2020-04-22" version="1">MGPLTLAASHNLVSDSVFGYQTNPPTQQVETIGSWQLEGLNKHSWTLSKDLLVSGTRPNFALAPVGYYGVIDKLQPFKVNEYKVNEYNDKLLTIHLEHLQIAVPLQSFLETAKLLQDYQYLNNRIYLLYFKVLSSSDHRSLSYHTNPRKNASDPRNRSHLHCCSHRPHRSRCID</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JV63</accession>
    <name>A0A5N6JV63_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydroorotate dehydrogenase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_006645</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JV63"/>
    <dbReference type="OrthoDB" id="14784at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.26.10">
        <property type="entry name" value="Dihydroorotate Dehydrogenase A, chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050074">
        <property type="entry name" value="DHO_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023359">
        <property type="entry name" value="Dihydro_DH_chainA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109:SF1">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (FUMARATE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="7">
        <location>
            <begin position="2"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8291864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="186" mass="19272" checksum="DC9D4333FBA6B72F" modified="2020-04-22" version="1">MMEINLSCPNIAGKSPPAYDEQALASYIKAIGSVKAGRTQSIFVGIKTPPYTYSEQFKRLVSALELGSSLLGNNPISFITATNTLGSCLVVNELGNSVLSSSIGEGIGGMAGDALHPIALGNVKTIRRILDASRVESVRATQIIGVGGVKDKAGFTRMSNVGASIVGVGTALGREGVGIFEMIIQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JV70</accession>
    <name>A0A5N6JV70_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_008160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JV70"/>
    <dbReference type="OrthoDB" id="3918601at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8292436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="191" mass="22106" checksum="5D9F007C4677FECD" modified="2020-04-22" version="1">MVERPCLFRKWNSTLYYRFSMLEWFSAARIGVPHRSPNRKRFDRPWYPHKLYTPQIIMICVTYCAGSTLYNLCGIRGLRGWFFCDQFTGNPEVLVSFPRTRIAPDIGFSSFFPSLLIEPTRGGSLSHVVRGTLQYFLFSSPFCKAQFGSSLKDIVLDNSQDHASFKVFFMNHRYPALQSTMIESSYSSTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JV74</accession>
    <name>A0A5N6JV74_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial transcription factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_007261</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8292896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JV74"/>
    <dbReference type="OrthoDB" id="16079at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034245">
        <property type="term" value="C:mitochondrial DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034246">
        <property type="term" value="F:mitochondrial transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006391">
        <property type="term" value="P:transcription initiation at mitochondrial promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="entry name" value="Ribosomal RNA adenine dimethylase-like, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF17">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="23"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8292896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="762" mass="87104" checksum="C36BB7CA1090BD7E" modified="2020-04-22" version="1">MINTSTLQQFICILYSLNVNNEKPPVKRTRRKSVSSKAAEGSDESPVKVKKSRVTKSVDSKGSEEQDGLAVKPVKRSSRKSASTKSVGDNQVKFVTQTQTSLNTSESLPLPVEPEIKKRGRPKKVTLENESLETEPVKRKRGRLENPMFEDEDFEIEPAKLLEEEADEINEEDFIKIPHTLRRYFTEAHKAGAAMGDRSRINIVNEALCDDIIDRLKPSLLKHVGCDIIDINPGIGLWSSKIHDLLKPRTHILMDPDSKKYLPYLQPLLDAENSTYQYIPKAGTVWEHLGQVTTPEFLPHQVKLSRDDPKINEPNDTLLVIANLGHFPKKKFRGFDSVSQLVMYQLLAAARSHALFHQYGLIRMLIWIPDEEKTTWLVRHIAQMRKNAVEAQITTKYIREVASSTVDNHRFVRDSEAALQNSINVVSNMDRMGISTPKYRQGEMEIKARKSIAAGGHEVKVNDFERFKRGWVAEWEKLQKKKLNGTLIKYENQGEDGSVNGGNQKKVYSHEFKRLSFLNAKIKTVNEHGILTDDLINDYDQINKFQGELAKGNPDSVDMQNSRDKLEAMIEEYDRKVEKLPSSAFRIYGIRLDGARITTEFEKREVEPLKVYAKEFIPSSEMCLLDIQPQALWPILRQNYPENYDVFEYIIGTMYAHPIDTVYESLEGLWPGAMEYIVSDCPSLTDPSKGGGFDLKHMTVRSLTTEMLKEIVHAWMKWPFRPTRYELMTKSGSIVHDPDNVEDDSMDGPGAKFVKMTPYLYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JV75</accession>
    <name>A0A5N6JV75_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sur7 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008166</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JV75"/>
    <dbReference type="OrthoDB" id="4159154at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051285">
        <property type="term" value="C:cell cortex of cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052413">
        <property type="entry name" value="SUR7_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28019">
        <property type="entry name" value="CELL MEMBRANE PROTEIN YLR413W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28019:SF7">
        <property type="entry name" value="SUR7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024958987" description="Sur7 protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8292446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="330" mass="35014" checksum="AF80ACB7B8D3B658" modified="2020-04-22" version="1">MVCSTVTFVLAMLCLFAGNKPGFMEDYHIVTLNTSEVGQNLIPTKTSGSDSTPTSISVGGIVSSLSSISPAGIVSGLSGLIPREPGIGDDIANALGDIENGIADKVAKTLGIQDWYSLHLMDMCEGTYTPNATANGAGLNVSSCTNQTAMYHFDINSIISEQLSIGPLHLNLSDINWPSAIQDGLDTLSTALNATFVFYCIGSAAAGLAVLTSLAAIFITSRLFSFLNWGLASLGLFALGIASIIVTVLQNKAAHIINKFGNDIGLYAYKGHKYLVLTWVATAFIAVAAIAWIGIFFLGRRQEGNNFHEKYHFGKRSRQSGSSEFARRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWW9</accession>
    <name>A0A5N6JWW9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWW9"/>
    <dbReference type="OrthoDB" id="5590473at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18724">
        <property type="entry name" value="PIN_LabA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007681">
        <property type="entry name" value="Mog1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837:SF5">
        <property type="entry name" value="NYN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="63335" checksum="6DD9E02371102146" modified="2020-04-22" version="1">MIESSVPPSWDLVPSIDLSDDPTSNEDDSNHEPWDLTPAVDLFDRLIVSNEDDSDHEPSYFDYISKNDQSITSRCTSNTLGDFTKIWNYLNNNASTHCQEIDEGDYESASPSFSSGDVFSGPDSLPDSLPSPVIDNSDTPDIFETYVRKSKEARWKSEVRGTKFPKQTQRRQSIRDLENDSEHPTLLSGTELNKPIAGQVLPQKKLASSPLATDRLFEIQSPSLQRSRRTLQQKFYSNSQTDESSGLESGIETPSRLKSTNSLARVPIGYIDNDLISGAKHLLYNSIFEEQRKAIVRKLLRRSSVDKYTLLKPPTFSQRSTDPEAIHIFVDYSNIIIGFNQALRRAIPEEVQMKIPLFSYRSLSFILERNRPVARRILSGSKQPHISKLPGHFIEAQRYGYETNIMDRVWKDRELAPKKMLRGRGNGYLNGQSSESDTPSSNKLIKAQCEQGVDEILHLKLLETLCDFNKPSTIVLATGDGAEAEYSGGFFKNVERALEKDWKVELVAWKYGLSHEYRSKSFRQRWGKQFSILLLDNFCEELLGIWAEQEVPAGNLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWX5</accession>
    <name>A0A5N6JWX5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWX5"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="102" mass="11101" checksum="860557552BAE3708" modified="2020-04-22" version="1">MPTSEIRHTTQKSNLTVSQQRSIIPPSSAQNTPSHPKPSHTYGPMHTHSQQPIPTRMRSAPTRLLHHQVTCRGFQAVEILGEDSHIEAGGVKFADCVDGVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWY1</accession>
    <name>A0A5N6JWY1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar import/degradation Vid27 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_007756</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWY1"/>
    <dbReference type="OrthoDB" id="10251113at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040458">
        <property type="entry name" value="Vid27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013863">
        <property type="entry name" value="VID27_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040768">
        <property type="entry name" value="Vid27_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913:SF0">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08553">
        <property type="entry name" value="VID27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17747">
        <property type="entry name" value="VID27_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vid27 PH-like" evidence="3">
        <location>
            <begin position="85"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar import/degradation Vid27 C-terminal" evidence="2">
        <location>
            <begin position="269"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="612"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8293446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="639" mass="72112" checksum="AD06A8537369F21F" modified="2020-04-22" version="1">MNLKFRRSHLTATVEELSQFAFEEEEPIPHASPPISPTTTLSPVQSFPAIDQAVTRRHRPESPPPVDEGPTKAPVVANHPEAISVLAEETAELHLFDFISGSFIKQDDEVTATVTEVGKWQYWLQITGKERDWLGHAVIADINPVFNFEYKSFIFNAYTPDHQAYSWLLRFKDQETIIRFQEGLMQALWEQLNEIKWNKSKEDERDYVLEAFQDLTMEDAPDIVEGEEEEEEEEEEEEVEDEDDGQKSEHYDSDEDEDDVVTRDDDGNVNSQLAVGYKHDRSFVVRGSKIGVFKHTPNNNLEFSTNISKVQTPSGKLFSPKKVMLHAEDTNMILQDERNPNSLYKMDLEYGKIVDEWKVHDDIPVNTFAPESKFSQMTGEQTFLGLSRNALYRIDPRLAGNKLVDSELKQYVSKNDFSAAATTEKGYIAVASNKGDIRMFDRLGINAKTHIPALGEPIIGLDVSADGRWKDGKNEGKLGFEKSFGKDSKPQPRRLGLTPAHVAQFQHETGAALSFTAARFNTGEGISETSIITATGPFIVTWNMKKILRGSKDPYSIKRYAEEVKADNFKYGSDKNVIVALPNEVNMVAKQSFKKPTRESIATPVRVGWSNGRRDSARIGGKDSGRYKLGRDDVVNSPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWZ1</accession>
    <name>A0A5N6JWZ1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWZ1"/>
    <dbReference type="OrthoDB" id="5376140at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="374" mass="40805" checksum="521F650EC77452D6" modified="2020-04-22" version="1">MALGISLRNAWLKCSPEGDKAKILANNQSSVAVGEKPRETTSSTASRTIQVVLNKLRKVGQHTFETSKGAINGTSALPSSSSESVRSSLSGFDESGLSDSITNPRGIPSKIQKKRSLIHNADKPARKSPRLSPAIDLPSMARELFAKSIYNFEPRSRPSLTSTPPSRNVSVQSVFEARQECASPGLYSASPPSRTVHTQRTNTPRNTNRINEQPPSSRDNPIIIDDSEDDKEIIRVQSGPLSSTLPSQNTNLRTETPKASGRLKSLSSNSLHGKNTRCIADITKSDDEGQATSSHSSILEVRIPVASSFTRTNSTAKPISSRFKSSSQALDANKLEPEKERKYIPVSNSQFDAYAKTSQMMKNADKRMRESLHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0F6</accession>
    <name>A0A5N6K0F6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_007172</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0F6"/>
    <dbReference type="OrthoDB" id="10017208at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF146">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="40"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="353"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8295261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="394" mass="43432" checksum="36DD198A51FE549A" modified="2020-04-22" version="1">MSTLWVYNSTPDANAESEYVLILGGTIPLLLFTAITVSGRLYVRIRTVRGIGADDWIIVVTMVCAIIYNAMTITQSRWGLGLPLELRPPEDLNSYSLLNYVGRPFYMVGILGFKVSLCFSYLRILSMGQPNYRLLVWIVMALCTLGHLIGTLVLMFSCDPIQRSWRPATTPGTCLPIAPLFYGLAVVTIIFDVVVFVLPIPFLSSLRMDIRKKIGIITAFALGLFTTGCSILRMKEINFIANGSGNSSRLALWGNIELDVGIILTCLPVLAPLLKVFGHKFSSYGKTGSSNPYLPTGSHNLQVFSNNRSHQHNTTTNANANASTRVAKSSRYMGEVSDNESQETILGKNQAEGNRRVETSADRRSSDESKNIDGIMRTMQVEVIEISGKTDSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0G1</accession>
    <name>A0A5N6K0G1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aegerolysin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0G1"/>
    <dbReference type="OrthoDB" id="2727348at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019836">
        <property type="term" value="P:symbiont-mediated hemolysis of host erythrocyte"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.270.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009413">
        <property type="entry name" value="Aegerolysin-typ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06355">
        <property type="entry name" value="Aegerolysin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="170" mass="18577" checksum="C7965D72AAAD9238" modified="2020-04-22" version="1">MKVAYNLPLKEIINHIIYKTIKTRSLLIMPGNAPDGYGDYIVVHLINSMMTSGLEIKNATLKHGKFHVSGNKDVEIPSEEVNRTIIAPNSAQDISSSGRSSALYGTEGSFDLYESGTKICKLYWSDPYSGNNDFQVQDYKIGGSYAVAVGPWNRSGGSLGRVDVEVVKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0H4</accession>
    <name>A0A5N6K0H4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U4/U6 snRNA-associated-splicing factor PRP24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_007199</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a recycling factor of the spliceosome, a machinery that forms on each precursor-messenger RNA (pre-mRNA) and catalyzes the removal of introns. Chaperones the re-annealing of U4 and U6 snRNAs (small nuclear RNAs) released from previous rounds of splicing, an initial step in reforming the U4/U6-U5 tri-snRNP (small nuclear ribonucleoprotein) that can reassemble into another spliceosome complex; this step involves binding U6 and facilitating the unwinding of the U6 internal stem loop, followed by base-pairing of U6 to U4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0H4"/>
    <dbReference type="OrthoDB" id="360390at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12297">
        <property type="entry name" value="RRM2_Prp24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12299">
        <property type="entry name" value="RRM4_Prp24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000632">
        <property type="entry name" value="Pre-mRNA splicing factor (Prp24), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000588">
        <property type="entry name" value="Pre-mRNA splicing factor (Prp24), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000711">
        <property type="entry name" value="Pre-mRNA splicing factor (Prp24), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000365">
        <property type="entry name" value="U4/U6 snRNA-associated-splicing factor PRP24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034398">
        <property type="entry name" value="Prp24_RRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031766">
        <property type="entry name" value="RRM_occluded"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23189">
        <property type="entry name" value="RNA RECOGNITION MOTIF-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16842">
        <property type="entry name" value="RRM_occluded"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="607"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="698"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="829"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="518"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="777"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="919"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="930"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="949"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="970"/>
            <end position="980"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00093374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00093627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8295294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="999" mass="113068" checksum="0CF6D5E13942E9CC" modified="2020-04-22" version="1">MGEPPVSEEDFTFLLDEASRNARDLNQRVEVVELYKRAISAEPWSNTLWLARCEWVLSLYTDCRDPDAGWPEEEQMLGQELFSLQMVQELWQEGAAATKFRLNDSHELWNRWITIELEELAKSPSREYVERVRKIFFDRLQTPHAKWDETSQMFSTFITKYDEPSWESTMVQVTQMGSPAKYLYAQREERELKLQQAITASDKEGTASVMREYLEWESLQPLKKPKKGLPHSPQILTVALYERALASTILGRDPGTWEDYIAFVQQSYAVNPDAQLGNPLYIAQRATAHCPWSGSLWARYMLLAETQNLDFTTIADIKHAATSTGVLDREGKMDEVIEVYIAWCGYLRRRTLGKRLDDEAFDVADVGLPGSLETVQDWGRRLHKREYTGDPSFRIERILIQYLTQKGSIEEAREFWKSLVNTHQKSYVFWQQYYFWEMTVRNPNASPSLPSMVLSQAIRTKDLDWPEAIMDLYIAHCNNYEDAHTLLEAKDLVRRQFQLVVKRRERLAAEQAELYAQQQTQVITPDPTIEESPGNSKRKREPTSEDVDATAFEKGSREHDLLKTEADNLSSTCLIEFRSNDDVQSAFLRDGKFFGENQIKVESGTGLTLYLTNYPPSADEHYMHNLFKDCGEIFSIRWPSLKFNTHRRFCYITFRKAEAASAATQLDGKLLENKFKLVAKYSDPAGKKQREGATAEGRELHITSLDSSLNENDLKEVFAKYGKVETVRILRAFNGESKGAGFIVFEKKEEATAALELDKTKLKSSVLHVELTQTRNYKPIATSREKGTSASPAPDADGDHAMSSASVVDHPHHNQHALHQPSNPESANRTITLLNIPDTVNDARIRAIAAPFGTITKIVLRPDHQGAIIEYEDVASAGKASLALENHEIVPGRKLRTGGMKDLFAQTSEFKTDRIVIGQNGKKEKEKGGVSTSTNNFMQPSAPVRRPGGRGGLGQKRGLGFSGPKKAETNSDANPTGLENLSLKSNADFKKMFLSGGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0I5</accession>
    <name>A0A5N6K0I5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0I5"/>
    <dbReference type="OrthoDB" id="14911at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01254">
        <property type="entry name" value="PH_PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="721"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="741"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="829" mass="92586" checksum="D5820B231B6B5317" modified="2020-04-22" version="1">MTQSTAGSISPSTRTPRSQSPANTHKNGSTAVRPSGIRTLSYEKPGTSLNLAIPTPHANGVASNVSDEAVDYLNGGIPHNSPIAPTSDIVSPGTSVNHATPNFSPVPPPSSFPHESHSAINGISTPPGRRSVSFARDVNTVEPQSSARQDSWGVEDGEPPAKDKIGGYLMSKLKLLTTTSGMQGHGRSQSTPTNYFDEGLGTTPIPTNIPHTLQEESSDADAEETADEGPSNQPTRIRKKRRTRRPQENESVPNTPRIRGYGPSDSPGGGRSFFLGRRATDGSLEQRGHLSEGEGRDRFAKQSAWRRGSSWMPGRGAIADTSPTQAQDFANVDGARSKRPSQFRRMTGLGGQSEGEAQTPRRPGYFGADRASTFGTQKWRLIKHSMKFFAGKGKKEDKVDYLKSAELMAELRAVTPAVLMIASMMQRDEHGNKRIPVLLEQLKIEITDSKPTDEEAEDTERHLVFRIELEYGSGPNRMKWIIHRSLKDFANLHLRYKLQGSSDKYIGNEAHARPKQPRFPKSAFPYFRGVRGLGESDEDEADNVRGEETAAEATHGEATQSEAEPKRKVKRRPSMSAARKSTRAILDPSGNTVSAEKQKRIFNERQRRRLEQYLQEMIRWLIFRADSNRLCRFLELSSMGVRLAAEGSYHGKEGYLAIQSAKGLDVRRILTPNNFFERHSPKWFLVRHSYLVCVESPENMHIYDVYLVDGKFEIQKKRRKIADMGKGKEKEKEDVSQAGRSAKHPQHHTLKLQNSERKIKLLAKNERQLRQFEDSLKYMAANTPWAKEHRFGSFAPVRTGVTAQWLVDGRDYMWNVSRAINEAKDACCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0J9</accession>
    <name>A0A5N6K0J9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidylinositol-specific phospholipase C X domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0J9"/>
    <dbReference type="OrthoDB" id="7984201at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF146">
        <property type="entry name" value="PLC-LIKE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26146">
        <property type="entry name" value="PI-PLC_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024851608" description="Phosphatidylinositol-specific phospholipase C X domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="31533" checksum="3FF8B7EC6C82BC01" modified="2020-04-22" version="1">MLLTLFYLWACITVTVAQVCNGYSELCGRKWSNISQIGTHDSAFVGDLPTDNQDIDVTAQLNAGVRFLQAQTHYSFGVLKLCHTSCWEEDAGPAVDYLSDVKKWLDANPNEVVTLLLTNGDYIPVGNFSAVMEASGLASYAYIPPHKLAIDEWPTLQEMITAGDRLVMFTDYGANTNIAPYVLPEFSYFFETAYDVTTPTFPTCTLDRPSGSNGDGLLPLINHFLDVDILGISVPDRLAAAKTNAATGVGSIGAHADLCTETWGRKPRVMLLDFFNTGNALAAQNTLNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2J9</accession>
    <name>A0A5N6K2J9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2J9"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="299" mass="33891" checksum="7F38586DADCFD616" modified="2020-04-22" version="1">MSTTEKPNTSSEPTPQQVEDPNKDNESIAIGFVADILVDILQRVQWNNRDDLHEEIFDGVLTLILEHIGQLLSVSIFGERVSDSDNPGNISFWEFSKEQSMKDCDFKLKSKYLIHIFDVALKVLNEKKMGGKTEKLVKQAYKKIRHTLITNTLGGNLEDLRIPEQVQPNPLDRPTLEDLEMYSPKWAIQCIFTMVGIADDEFEGISEAAISRAISGKSKFVNRNTGTEYRFEDGAEDVVTDAIELAIGDALGLRTDVENSLEYGYEDDVEPAEEVQSAVNLDPEERLERYRYPRSTRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2K1</accession>
    <name>A0A5N6K2K1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_009107</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2K1"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.330:FF:000030">
        <property type="entry name" value="Thymine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="191"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8296342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="347" mass="38632" checksum="C69C87B74143F876" modified="2020-04-22" version="1">MSIETAKAVDADNLVIPIINFSNFLTGSPSQRLQTAKSILHGFRTAGFIYLSHHPIPLPTLTHTFTTSAKFFSRPSFQKDPLAWTTPLANRGYVAHGREKTTTLTDKTKVALLKAQAPDLKESFEIGREGEEELPNNWPPITPEDGDAKNFKEAMLHFHDLCKQLHINVMRAIALGMDLPEEYFDEFTSAGDNTLRLLHYPPAKASAFRENKLQVRAGEHTDYGSITLLFQDDRGGLQVKSPKGTFVNATPVPGTVVVNAGDLLARWSNDLIKSTLHRVVEPPPKEGQEIGEEGVYPARYSMAYFCNPNFDRMIEAIEGTYGGEMGERKYEGINSGEYLVQRLAATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2K2</accession>
    <name>A0A5N6K2K2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2K2"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="83" mass="9339" checksum="E4696552E9DC5C64" modified="2020-04-22" version="1">MFLHVFFIFPETSGKPLEEVEEIFDYSTPGSIKFLGTPAWKTGVDHRARRLERGEFDAEDKAGPTVAHHDGATQINEVSKSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2K6</accession>
    <name>A0A5N6K2K6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2K6"/>
    <dbReference type="OrthoDB" id="10584948at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="152" mass="17530" checksum="A46678529C3B4987" modified="2020-04-22" version="1">MISSKLLDVTQPSQFLLFLQSTTRISRTTGVIAILASAEEEKLEIHFEHSTREVDIKNRNSTLELLPSLDPKKVVLSHLYPLQLYKSKRLDLRIFPKFKIPQSTTTYPLTISSGSHPPRRLDEHKLYLIKSQNPFDHPNHPTDLFVRQSQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2K7</accession>
    <name>A0A5N6K2K7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2K7"/>
    <dbReference type="OrthoDB" id="5418088at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42081">
        <property type="entry name" value="ZINC FINGER PROTEIN DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42081:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="536"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="692" mass="79693" checksum="9411C5696A1BD1B1" modified="2020-04-22" version="1">MSDRYSRHPRPRSPTYNPARTSLPVDLSYNNHSSGSHTHHHHVVPLSRHENPRSSSTSFNSSNVPITTTTYKVKPDHRAASRTRSNTVESRPNTHTIFTSIPKHPTVVHTSVVRPASPSTKNPYRASQEEYYTIPASSRNDKSSQHHSRYSASMDNADMNRLPRESQGHRDPNHLRIGIPSIRDIPYTTPATAPLYATTTAPAYIPTPTSSFIPTPITSYTPPASTSYTPPASTYTAPLPTPSYATTTTTTTKPRGPVYTANLVRHPDTVADDYGDDGYGYTNPKDLVQYDLNNSVPRHTRKDSFDTRSSRPSSAGFVETVQSPRSYDTRERGPPPSTRGFDRIQSWDTQPASARMPVPHVAPMEPVQRPHVTPMEPIQRPHVTPMEPIQRPVRMDPPAGYESDGPQRRTSTRRPVSMYQERDARHPPRDEYYGSREEEMRERRPQHRHERYDDPVEQRGFGLRPERTERQERPSSRAERVERTERPASRAERPERTERVERVERVERSDRHERSPRNEREDDRREKKSSTHEKIATGLSIASAALSLGAMANTMKPDDRDDRDDERRRKDYGDDSRRRRDRGDKEMVDSSNERRFNDSRDSSESDRPDRKERRERRHHSERESNESVGRETKERHRDRDITPPLPPRPREEDDVHQPRKERSGEEIPSNSRDVARDGKDRRTSKYSKRPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2L4</accession>
    <name>A0A5N6K2L4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_009147</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2L4"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024909875" evidence="3">
        <location>
            <begin position="23"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8296403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="197" mass="21974" checksum="AB117976BD006C38" modified="2020-04-22" version="1">MLSMLRVKRLSVLFLTFPLGGLNVLDSDVASIRRREDAEGDRYSCVKVQVDDLSMREHFSNTFQRTERISQEGSLLLEVEGRGKKTEAKVNILMMMMMMIVGVVLAGCAKSCICVDMWGWEKCMGVGLKEVEKGGGGRGRGREGKGRERDSGNQGGWILFSNVKFQSSVFHFGIDVDIDISMNLKSTRKARGIIPMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2L8</accession>
    <name>A0A5N6K2L8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_009122</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. DCP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2L8"/>
    <dbReference type="OrthoDB" id="18996at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140933">
        <property type="term" value="F:5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03672">
        <property type="entry name" value="NUDIX_Dcp2p_Nudt20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1050:FF:000003">
        <property type="entry name" value="Decapping enzyme Dcp2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000003">
        <property type="entry name" value="M7GpppN-mRNA hydrolase isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1050">
        <property type="entry name" value="Dcp2, box A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007722">
        <property type="entry name" value="DCP2_BoxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036189">
        <property type="entry name" value="DCP2_BoxA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044099">
        <property type="entry name" value="Dcp2_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114:SF17">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05026">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01125">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140586">
        <property type="entry name" value="Dcp2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="10">
        <location>
            <begin position="98"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="354"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="579"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="685"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="725"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="837"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="579"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="688"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="740"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8296361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="907" mass="100682" checksum="EDAD6582A64AD9E7" modified="2020-04-22" version="1">MTDRKLQLEEEFQRLDDLCVRFILNVPAADLEHVPRICFQIEEAHWYYEDFIRPLDSSLPSMTLRNFSLKIFSHCPLLQEFPETEHMRAFQEFMDYKGRVPVRGVILLNAEMDSVVLVKGWKKGANWSFPRGKINKDEDDLTCAIREAFEETGYDVERSGLVAQDRSLVEGLDVTGHGQQIRLYPFRDVPMDTFFEPQTRKEISRIQWWRLSDLPGYNKKGQQQHQPEAAANANKFYMVAPFLPKLKKWIFNQKREDTKMAAKNWQLEAAGNISYDEGITEDDQPVEPRITYNTSTSREAERTRRDAADLALSALMQVQPPTQGLQPNTIKPAQSQTSHSSGQQLLALLHSKPPVDQSTVTRPSLQTPSDQTIPQPSLPKAPHYQLPHPSHGPYQPPPTFSQQQPHEQRPMQTYSYQQPDFHVRHDQGSIPNMQYHHPVSQQMPQRRPQHVPPQMQQQIQQQQIPQQMSQHVPQHLLQQIPQQRERHPYQPPLIHPQPLPPNAQKVLFAGGPAHSTMVPPSIQQQPLHHNFPVSGAMPLPQFHNVHATMVAPQQKEEPAALTSHSLLLLNAFKTRDQVNGNATSSQLPSQGPTKSHVKASMPVAQELPGESSRSIPVPFPIEAVESSKIVPGLNAGTSSTISHNQTAPPPVSEHQRSMLLAVVDLPTSGSPSVVELSAVEVVSPPPISQQRSTNGDAAISQASPENTEMNPELNLPFRAKSILTHPENGHKNIKPYGSLSKKSANRSEMQNSSKISSKTSPERSFQPQILKRPQANTVKASPLLAPSTIAAYSPSLAPSNIAGSSTSPLSFTSQAPQSTEQKHALLSLFGKSPMAASSSISRASSHDGPSSNPLIDATRSAAPRSRVGSLASGNDEGMSRRGSQTPISPADKGFLLNYLDAVANRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2L9</accession>
    <name>A0A5N6K2L9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8032 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_009130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2L9"/>
    <dbReference type="OrthoDB" id="5599902at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058345">
        <property type="entry name" value="DUF8032"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949:SF0">
        <property type="entry name" value="RE27538P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949">
        <property type="entry name" value="WHITE COLLAR 2 PROTEIN WC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26087">
        <property type="entry name" value="DUF8032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8032" evidence="2">
        <location>
            <begin position="154"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="381" mass="41818" checksum="BCAC9AE3C1ABF52B" modified="2020-04-22" version="1">MYAPSSQLQQNPQMYYPGPPQQQYPPPMAQGGPSPYAQQQPPPQQQQHHHQQSMTSQPTLLMSHQANQHPMQQHPNQHQQPGMTGSPRPKMEPHVPQIARPNPPLGAQHSANGAPQMQSNNVPGTGGSGVNPNAAPGPIPATTPLVVRQDNNGVQWIAFEYSRDRVKMEYTIRCDVESVNVETLTPEFKTENCVYPRACCSKDQYRGNRLVYETECNTVGWALAELNPCLRGKRGLIQRAVDSWRNSNQDPRLRSRRVRRMAKINNRKAVQAATSHNSHMTGPSPTGMPPSANMGPGGAGSMGKPNLSGMGGPQLHHHHAHPDGSNQGGEEVVTKALSCIIQHCTLLPAFRDTYPLPRVMSSYYCIAPHCLLCIVIVLLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2M8</accession>
    <name>A0A5N6K2M8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Translation initiation factor 5A-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_009146</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell septum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-5A family. Hex1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2M8"/>
    <dbReference type="OrthoDB" id="9975114at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140266">
        <property type="term" value="C:Woronin body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045901">
        <property type="term" value="P:positive regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04469">
        <property type="entry name" value="S1_Hex1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000229">
        <property type="entry name" value="Woronin body major protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000033">
        <property type="entry name" value="Woronin body major protein HEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037318">
        <property type="entry name" value="Hex1_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048670">
        <property type="entry name" value="IF5A-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21485">
        <property type="entry name" value="IF5A-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Translation initiation factor 5A-like N-terminal" evidence="5">
        <location>
            <begin position="532"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="149"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="307"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="197"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="329"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="348"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00061629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8296400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="677" mass="78372" checksum="C6D055DB0BEC6CCA" modified="2020-04-22" version="1">MYAGRSISFTQHRISIRAINSFHTHPPYLLFAHPARTTPTIIIIIIIKIFTFASLWPHLQRPRDNFLKLKVESRNVNQNVFFPLPSTSRSRDPSCDILSVVNLDFDARVPIPFSIFPSSYRSDVAVQHIQTTETHVEGELTLPHHHERVGREGQEEDAQSLYSQHTQHQHQHQHQHQHHLPPPSPQENLPPPPQRQEYLEEEIHITREEDRRSEYRPSRTEEEEVYIREERRLSNDLRFSPSPPPYPKIYMGSFFFLLVLTRPEHKHKHHSASFDINTPHHHRHFEASFERDSDRHHKHTEVNIELPRREHNHHHHHHHRRPSSEVDYQLERVRQPSRYEHSELDSASEFSVPQKSPTETQIDFVERQYRSRTQPTYKEDPVIVDPPQSRVSEPRYIEETRVTETTIVPAPARSTHSNKPKSTFYEEKFEEVHVKQPRTPARSTFTEEIRDRGLVKYSPPAPKSTTSNFKPVNLEMGYYDDEGKLYLSLSGNYHSLRGEDYHGSGKHIYQDPIDSLDLASAPVVAAPKQPPNTVTIPCHHIRMGDLLMLQGRPCQVIRITTSAATGQHRYLGVDLFTRQLNEESSFIANPSPSVVVQTMLGPVFKQYRVLDLQDHTVVAMTETGDVKQAVPVLDQSNLWTRLKEAFEGGRGSIRIMVVADGGREIAVDMKTVHGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2R7</accession>
    <name>A0A5N6K2R7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2R7"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="96" mass="10366" checksum="9C997E5E1F6BD45F" modified="2020-04-22" version="1">MKKYNTLPHNRASRTSTTTDGQYNTIQTLHPAHLLYQLLNGVQEDGAWLVLGRRRGYDDQRDLGIWGFACGLGGVGGVGGSGGDDDDDDDDEGSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K330</accession>
    <name>A0A5N6K330_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">6-phosphofructokinase</fullName>
            <ecNumber evidence="4">2.7.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">EYC80_002160</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="4"/>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K330"/>
    <dbReference type="OrthoDB" id="537915at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005945">
        <property type="term" value="C:6-phosphofructokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070095">
        <property type="term" value="F:fructose-6-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061621">
        <property type="term" value="P:canonical glycolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="entry name" value="Phosphofructokinase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697:SF4">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="16">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAB8296740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="198" mass="21872" checksum="61F309FFCF253E6E" modified="2020-04-22" version="1">MAGLAVGASAVYTPEEGVSIAMLSADIAHLKKVFEKDSGQSRAGRLILINEKASKVYHAKLIADMIREEARDRFESRDSIPGHVQQGGTPSPMDRTRAVRLAIKCIEHLEKFGHQTDKEIIADKQSSSVIGIKGAKVVFSSMVDVEENETDWPNRRPKDEFWLGLKDTVDILAGRPDVPRPEGKLIGWKAKDSKRGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4P7</accession>
    <name>A0A5N6K4P7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribonuclease Z</fullName>
            <ecNumber evidence="4">3.1.26.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_002636</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="4"/>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4P7"/>
    <dbReference type="OrthoDB" id="527344at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990180">
        <property type="term" value="P:mitochondrial tRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047151">
        <property type="entry name" value="RNZ2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027794">
        <property type="entry name" value="tRNase_Z_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553:SF49">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13691">
        <property type="entry name" value="Lactamase_B_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNase Z endonuclease" evidence="12">
        <location>
            <begin position="6"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="171"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8297277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="598" mass="66909" checksum="E7D33D9EC7A065E9" modified="2020-04-22" version="1">MRSYIQFLTTPTADTPGTTLLLHFDNKRYLIGNVAEGTQRACVQNKISLMKVGELFMTGKVDWASTGGVLGMILTLADATSSSREAQFQVEHAKMQRKGERAEKPAKAFLNIHGGENLTHLLATARRFVFRNGMPLYTNEYRADSEKRQNWDPSWSDENIKVWAMAIKSEEHAKSPGKRTHDEFSDDSDSLSEKDQELKLKKAQELRDEEDKQHQVRKSVVSSMFDSDWKLDTLYTMKLRDVKMPAAIFVRDADGKIQKYQGPKPGGEEEVPDIEVLTRKPWPGALVESLPPTKPSTSSVSYIIKNHTQRGKFNPKEAERLNVKRGADYRTLAAGRSVIATDGTTVTPEQVLGESKEGTGIAILEVPDVSYIRPLLAREEWTSKEVISGVESVFMEEHKEFTHVVSSPDGSSNYLAFSSAAAQAIRLHLLDSERFPIPSFSNASVSASQPVPYSRARSGKTLLLEPKFEVQDEKCTPYLDTEQVVKETDPEVLALANEAKKEVMSPEYQAKLDEIQKDIPCKDAEVITLGTGSALPSKYRNVSATLIRVPEYGNYLFDVGENTLGQMKRVFGKELPDSSEHGMKKLLRMKQREITNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4P8</accession>
    <name>A0A5N6K4P8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4P8"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="207" mass="22960" checksum="32A98B50822C5E3E" modified="2020-04-22" version="1">MLLSHTPPVTKENDTSSQARKQIHTNAMGAYTITPQTPLAAPQNQYLIDYNTWISKALEARDLPPMPCTSIRPMLLQEAEVLEQIESRRLAIPLGEVRWEREGVGGSATSTNGLHGSKGKAKEGDRKQLTPGQAALRRTALMSIIQMIESLEPLLKEASGKSMDEWDRWCGNLMTDLLKNNGTCWGECLEVGAWWAKKKDPNSDSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4Q0</accession>
    <name>A0A5N6K4Q0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4Q0"/>
    <dbReference type="OrthoDB" id="3057168at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="425" mass="48591" checksum="CEBA78064E8650CC" modified="2020-04-22" version="1">MSEKAHMTADDLLLGGDTAVNGNLGRRRTRMGREEVVSYGSGPVSVIGEEMEPDEKLEKVHGISSYNGERRKSSKQGNQVYGQGFPLPVRSRTRITTDPRDSELERDMLEVRSEQLDRNKVGMGSRIRIVPDEEKERERRDREKDVGRGAPLIPRVEIQDPQQDEIVVFEEDDDSEERPRRRSRAGGRLRERSSAKTIDTWERSDVGESTLFAPAPSNRSRGRSGVGEREKERERDLSIPRSVDSWERSDVGESTILTQRTKSRTPKSRSRVSARDKRDRSSTRTVDTWERSEVGESTVLSGPGGRARTPRSGLGARDRERERSRLEKEREREREKERDSGYEGEVERAYGGRGYDGEGERWHGRGYEYKENRGHSPVPSRLGESRRDRKMWSERGSGMSGRGFEKRNPLEDVESPGKFVSIEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4Q5</accession>
    <name>A0A5N6K4Q5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_002678</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4Q5"/>
    <dbReference type="OrthoDB" id="1724687at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000554">
        <property type="entry name" value="Ribosomal_eS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047861">
        <property type="entry name" value="Ribosomal_eS7_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11278">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11278:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01251">
        <property type="entry name" value="Ribosomal_S7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00948">
        <property type="entry name" value="RIBOSOMAL_S7E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8297330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="207" mass="23306" checksum="D45CEA0C4FC4D36F" modified="2020-04-22" version="1">MSALNKIVATSPSRASPSELEISIAGALYDLESNTPDLKAALRPLQFSSAKEIEVGHGKKAIAIFVPVPSLQAFHKVQQRLTRELEKKFSDRHVLILAGRRILPRPKRSNRSRTSLTQKRPRSRTLTAVHDAILTDIVYPVEIVGKRLRTKEDGSKILKVILDEKEKGGVDHRLDTYSDVYKKLTGRGVVFDIVRWDSEGFQKWVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4Q7</accession>
    <name>A0A5N6K4Q7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4Q7"/>
    <dbReference type="OrthoDB" id="5422351at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="355" mass="39257" checksum="7D0F7CE6EFB5E569" modified="2020-04-22" version="1">MPGQPVNILWVPVEVTPPRLRSGSVDSINLAEAKTLNPADKFMTPRAPPLKPGVGRSTSLSSSHVEMSEKQCSMSKDKKVGWATKLFSGRRPRTSSPSEPLTPRRSSESDTNQAATRTNSSNSSTIHQPSPVRSKPVSRKPSPIRVYDSIHNNLIALGIPEENPEEDDDNNFATQFKELKDENSFTKLSPAPSRRQASPIFNTSKPLPQLPEDALKYPIAPLLPNLSLTLPRSHFSVSTISTVTSPTDSQFGFSDTSSMLDSYDDSDLNEETGDTFTYNPMISEVEKRRFIGYSLPDEEYASEQTIRKVSISQSTSNDNYSREPRFTEGMKQTGRSALADFLDDMGYLGETISDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K513</accession>
    <name>A0A5N6K513_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_002572</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K513"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045719">
        <property type="term" value="P:negative regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14004">
        <property type="entry name" value="STKc_PASK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000320">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000314">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057213">
        <property type="entry name" value="DUF7891"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF51">
        <property type="entry name" value="PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25421">
        <property type="entry name" value="DUF7891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="910"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="251"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="452"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="820"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="870"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="878"/>
            <end position="894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8297194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1210" mass="133229" checksum="0521A48EBB38E1FF" modified="2020-04-22" version="1">MLKTDTQKNYVFENNTALSIPKNRSTGNLLAHASTGTDKARIRFSFDEGLAAAEFDTMSSTRSPLVTEHEHGLGASGLRRIRQQLPRAPTLPISESSSRAPSTGARSSSMTLPFPSRAASIAMPSGPSSPTLPFTEDLTRFPSESLHSFSFAHQSDEFIHNRQNVLKRSVEFMSQKLGWGTTNAGIASAQARVSGDAEMQGMLELLAKAKLVGANNLGTEQEQARGGPLTGPATAHDSRNVFDSSFAIRSESPEQLGSTPPSPTSAKKATSSLHTLREDDLPVESKNVLVPALPTDSESSSRTPTNESRTTAKTSPPITRRQSLKRTYTDLEPLNLQNKLMDAMSQPYIATDSLHESMFAPSMPQTASATTFGPHSMGPANHSHSSRWAPAAQAIFTTESTSPYTILAANDLACLVFGVTKAEVRKMGILEVVQKERRSWLEEKLSAHKLGSEVGKQPPQSPPSQSQQSSPTLTMQKPNRRAQTDDGAGSSLVSRTRAVKGGLNHQSNKSRGVLLCGDVVPIEKRNGATGSASLWVKEKRGGLIWVLEEIHEDVAIIGLDEDAAIKSISGSIDAIWGDNITWTGKDIGKLLPRLPRQGIDGRSGEIDYAEISKRRYFTARTSGRVNIPAVVDRIPGGTDLRVSSFPHIAGIMVLSAQTLKITSSNSVFSAALFGQDKPDGRLITDLIPDFDRMLKILTEEDGVDMVDGIVIPEHSFRRAQAFLALRDGKADASTYFLRPDGLPAKHRDGSEIKIDAQLRVVKSDYKTSAYDEDVIEERSDEEDGPTEPIIQSELVYALWITYSRNIHAAKNATGMATPLLSGLETPLHQPSPGQTGPPAPIKMDSSSDSDEPKNEESHASMLTAQLKAAAKKTAAKLTGRDRSSSKPQEKEKPAVPEAAKPVVKKCIDDFTILEEMGQGAYGQVKLARYKKNGNNKVILKYVTKKRILVDTWTRDRRLGTVPLEIHVLDYLRRDGLQHPNIVEMSDFFEDSVNYYIEMIPHGYPGMDLFDYIELRVNMEEKECRSIFVQVARAIHHLHTKALVVHRDIKDENIVINGEGNIKLIDFGSAAYIKSGPFDVFVGTIDYAAPEVLSGKPYPGKPQDVWALGILLYTIVYKENPFYSIDEIMDRDLRVPYVMSEESIDLIRGMLNRDTESRLTIEQVMEHPWCIDTDESDEPNTEKIEMKEIFGQLKKKQEIHKRGAHLDFMIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K570</accession>
    <name>A0A5N6K570_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K570"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052594">
        <property type="entry name" value="J_domain-containing_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="24"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8297723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="301" mass="34428" checksum="19DF046C855817DC" modified="2020-04-22" version="1">MIERDFGTLSDKDDVIQSILNEEDLYKILGAQRSATCAELRRCYLERSKICHPDKIPFHPLSTRAFQRLAFSFEILKSPSSRRTYDSASFTSSSSPATTSLPTKHPSPSLASDNLFRTTVSSLIHDFLTGDFITIRSLLSSLNSQYPHLMNTDVTSSVEIAFVKVRELVMRGRIWALLIYIEMRRIWRVQKRLMGLRRWDLVGKARMFVLLVRVVVAVPVRVDRALRERVEREQRARKAGLETRGEGSKGEEEWRGGILNERVCKVLEFIIGDAVVSFVDVVFVLVDLEAEKRDPILEVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6U3</accession>
    <name>A0A5N6K6U3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6U3"/>
    <dbReference type="OrthoDB" id="61116at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="110" mass="12081" checksum="765B1DA806CD31C4" modified="2020-04-22" version="1">MDRAWAEGEGEADAAEPVASAPVSNASPIRKPEEAVSSVDILDEGKIECRGEFLASECFEFLSTQGCYQVFFNISVLAKQSLLLYFFGLVCYLSKVEREEACAHTARYGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6V0</accession>
    <name>A0A5N6K6V0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002044</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6V0"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055528">
        <property type="entry name" value="DUF7102"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057559">
        <property type="entry name" value="SAM_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23394">
        <property type="entry name" value="DUF7102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23395">
        <property type="entry name" value="SAM_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7102" evidence="1">
        <location>
            <begin position="399"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="SAM-like" evidence="2">
        <location>
            <begin position="574"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8298315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="666" mass="75003" checksum="9CF40CAEEDBA8634" modified="2020-04-22" version="1">MPSASGDQFVKPVEIYSPPEDWKYFNESPSSPLQGKGVVLADLKVEEPLTPLKLPLEESRPKSVHFSNIVEELLLSSRPQTGSSEAVLETKFFEEAFGESGDQANHRAEKERLVDTRNRVEVPVMDFNTSGPPWMLNNFHSVNAVSSILQRKIEEVGIDRSERWPGLKKLHVKLPWAPFKHDLGSVVGESLGNYDIWKSFVHGTSDEMAITSSDLTWKMEGLRILQQYEDDEEDELEIGYFPKEIEDISPLIGKRKSEMEDVEHRQRQKRQNKSYTCGATMQVEHMLTTPDMRHDKSKYQENTASNIPKRARPAAEEQVSLLEGIFSAKDALNNFLEIRGAKKPKLIESAHFSTRNTPPPITPYQTPLNNGAKSLEPAASETHVPLPTPIVVAPETSISIILSSTLLRNRLLVRSLQSLLPTLKISERDFSAHNTTIWNHGSVIRSPVTSTLTYEADIIVSPTTGLILTTLQHIKQKPLPGHKTAVPIRDRLEKVSGRYENLIILVSSPTIELGESDCMAWADFVGFTLTLQACIIMNYIPVDSNNPDDQVMAKYISALIIQHLPPSSYNLELLEQESYWEIWLRRAGMNAYAAQAIIVHLKAPEPRLQPGDEGYEVGMQTIDERGPYGLAWFVQMGALERMGRLGKLVGERVLERVGWTVDQMWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6V7</accession>
    <name>A0A5N6K6V7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglycerate mutase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6V7"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF32">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G10590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024891227" description="Phosphoglycerate mutase-like protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="49188" checksum="CB5BB20910CE32CD" modified="2020-04-22" version="1">MLSLTVLLSILSVVGATPAPIPTPAPYYDSLVPRTKPGVGSHGTTWVNYTAVPGFFLQDDEKTDPTIFDYTKENFGLINQTYPTDFQLPKDATHWQRFERYVESLNKNASSTVNYKVLFLARHGEGFHNAAETYYGTPNWDCYYSLVDGNATVTWADAHLTPNGIAQAKIAANYWLSNIQVEKTPSPQSYYTSPLYRCLQTSNITFSTLSLPESRPFKPLIKELFRESISGHTCDQRSNRTFIQESFPTYAIEQGFSEKDPLWRPLFGEPAFNQDIRSKEVLDDVFGSDKNTWISITSHSGEIASILRVVEHRPFKLATGGNIVSSTMDTSEDLYKPSPTRSYKVEWKETGEQKRVRFIQIRWIISWYRQSMIDQTSSQMTLDSYSIYKFVRIKAIRKVQIEVRDWESDEIEPDIITENDDIRDFVEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6Z4</accession>
    <name>A0A5N6K6Z4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MoaB/Mog domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6Z4"/>
    <dbReference type="OrthoDB" id="448496at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047884">
        <property type="term" value="F:FAD diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042726">
        <property type="term" value="P:flavin-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="entry name" value="MoaB/Mog-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47675">
        <property type="entry name" value="MOLYBDOPTERIN BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47675:SF1">
        <property type="entry name" value="MOLYBDOPTERIN BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="Molybdenum cofactor biosynthesis proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaB/Mog" evidence="2">
        <location>
            <begin position="51"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8298292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="397" mass="44111" checksum="C4A2E2E954A84610" modified="2020-04-22" version="1">MFSRFSQLARHLSRPLPNYAHNSAAASTLTNKVMTSSSADERNSRTIHTAACLIIGDEVLGGKTVDNLKRVEVIADDEDEIVEAVRRMSNNYDFVVTSGGIGPTHDDITYQSIGNAFGLKLKLHQEAYERMKRLSKPHPRQPNFNWDEDSPAKKAKLRMVELPLDESRDWSKQVIFPCEDLWVPVACVNGNIHILPGVPRLFEQLLEGLKASLLPRLTDPDGKGICRVLISTPMSESGVAPYLTELAARVEPKGIKVGSYPRWGKAHNTVTLVGRDRERRTQGNIAIKPPLAPSPPIRSRTNDDTPSNKFIQGPGLSAARNNERPFLPTVKSQASSRFQSPPLRGQRGKSYVQSIQYTRQTHSTSILRTAYSTTLVISNLQSQPWCPCVTRAEIQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6Z5</accession>
    <name>A0A5N6K6Z5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycolipid transfer protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_002075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6Z5"/>
    <dbReference type="OrthoDB" id="205255at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902387">
        <property type="term" value="F:ceramide 1-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902388">
        <property type="term" value="F:ceramide 1-phosphate transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3520.10">
        <property type="entry name" value="Glycolipid transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036497">
        <property type="entry name" value="GLTP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014830">
        <property type="entry name" value="Glycolipid_transfer_prot_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219">
        <property type="entry name" value="GLYCOLIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219:SF25">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08718">
        <property type="entry name" value="GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110004">
        <property type="entry name" value="Glycolipid transfer protein, GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glycolipid transfer protein" evidence="3">
        <location>
            <begin position="65"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8298351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="164" mass="18055" checksum="585B491CD57FB2A7" modified="2020-04-22" version="1">MPRVSSTQISFLVSISIFSSHHHHHHHHSSKMATVKAIPPGGTFIDTLDKSFVDVPVNKEKDNAIATTEFLQAAESLTTLFDVMGSVAFNPVKNDIGGNIKKLRERQLAAPAESETLQDLFGWFAVSTSPASHSPKTWQHRPTSSPFHSVMPMERPSSPTTPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K746</accession>
    <name>A0A5N6K746_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycolipid transfer protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K746"/>
    <dbReference type="OrthoDB" id="205255at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902387">
        <property type="term" value="F:ceramide 1-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902388">
        <property type="term" value="F:ceramide 1-phosphate transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3520.10:FF:000001">
        <property type="entry name" value="Pleckstrin domain-containing family A member 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3520.10">
        <property type="entry name" value="Glycolipid transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036497">
        <property type="entry name" value="GLTP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014830">
        <property type="entry name" value="Glycolipid_transfer_prot_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219">
        <property type="entry name" value="GLYCOLIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219:SF25">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08718">
        <property type="entry name" value="GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110004">
        <property type="entry name" value="Glycolipid transfer protein, GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glycolipid transfer protein" evidence="2">
        <location>
            <begin position="34"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8298349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="219" mass="24222" checksum="95CBA0AEF3494F08" modified="2020-04-22" version="1">MATVKAIPPGGTFIDTLDKSFVDVPVNKEKDNAIATTEFLQAAESLTTLFDVMGSVAFNPVKNDIGGNIKKLRERQLAAPAESETLQDLVINELKTKKHTATEGLVWLVRGLDFTCIALSQNLATSTDELSVSFRNAYGETLKPHHSFMVKPIFSAAMSACPYRKDFYVKLGDDNSKVEAALRVWLSALENLIAILKGFLDRKEAKCEQASDEFWDDMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8X1</accession>
    <name>A0A5N6K8X1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001267</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8X1"/>
    <dbReference type="OrthoDB" id="20507at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384:SF19">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26093">
        <property type="entry name" value="HTH_TGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="45"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8299163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="606" mass="66289" checksum="3A6AF7411C5FA778" modified="2020-04-22" version="1">MDDEDIADAAEAQRVQTAEGFAGLGSTQNDAIRRGAFIDLFKADGETMGVKLLKKMGWKEGQGVGPKVRRQARLDGIERPDADADATYLFAPENTRMISFLRKDDHKGLGFNGETKLTPSNEFGSEKHKSEDEDDDRSFSIAPKISKKKKKPARGGIGIGILNDTGSDDEDPYEIGPRISYNRVIGGEKKKKKKKKPLSPAANSLLKSKPVFISKKTALAKAAAGLRKCHDGRLPLDGFVLSNDSRTSSASETLSKYAPPTIPEGWKSAKQPQSHSTPSQYLSTSEAAKASKLDPQSRASILGEASLPGKSVFDFLSSSARDRLAAASGRSNLPQALGEIPEGYAMTPEQRQQELLSQIPKIDKYTADAALMRCSSIYGEDEAKRIRYRAYLEYQAGIVTTIPEKGLLTSKEDWLKELQEFANCAKIFKPMTGLMATRFTSSASSTILPGQNDAAKDLLSKPEVKEDPAEQAAKMGMYGPMTRERKDWFPTRLLCKRFNVQPPKHIQPSADEARGTGREAPPDLVGRREIDRMMIEAGTASGVREAEIKKEDVDVDVQLGDVIVKEEERGKQAVIDAERNEALEGQRAGEAVFKAIFGDGDIEEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8X2</accession>
    <name>A0A5N6K8X2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_001310</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CENP-K/MCM22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8X2"/>
    <dbReference type="OrthoDB" id="9445768at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020993">
        <property type="entry name" value="Centromere_CenpK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14401">
        <property type="entry name" value="CENTROMERE PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14401:SF6">
        <property type="entry name" value="CENTROMERE PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8299217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="279" mass="31620" checksum="9B6B30013729C14E" modified="2020-04-22" version="1">MTYPKPTLPSKGKNPPTSKPSPSKPASKNRIQTLTTTHHHRTHQNPRPTSHLPKTHPPHHQDALRHPNPPPSPRLQHLHHHTPRRQTRRRRTRRPHRKPKTSRSNSTPDPTTRQRRIDEIWGPAPASSPSETGDANEEPSAPKPPRNESQAAATELRTLTEQLLNALLEAATEGYESAGGYVTLARDSAAARFLVRSKVAQYHFRDARRLTLVDFGGDKRDNTKQVFEASKTSNASKVIGNEEEETKNITQKEKLNKVSLLINPQWLKYQHHPNIHSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8X6</accession>
    <name>A0A5N6K8X6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8X6"/>
    <dbReference type="OrthoDB" id="1077582at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="91" mass="10191" checksum="3E13A5CCD348EF4C" modified="2020-04-22" version="1">MNASSSLQFSIPTTISPAFETLGHETIRAAAFLLIPTELLYFSIYFLLKRQYGTYKKLSALSLVTFWLSSWMNPISCGPVGALRNFAGMYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8X7</accession>
    <name>A0A5N6K8X7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8X7"/>
    <dbReference type="OrthoDB" id="3830579at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="23993" checksum="DC6FFB3B1CDB9C19" modified="2020-04-22" version="1">MLVGDFGVGLDLGLGLKEGLRLKKIIGRREALQTVARQKGCTDSYYGAGEEEEGVLVWCIDWSSLAHHKAFMNSPAYPPFLKSLAPIMKSAQIMHVPRLSLNGAIGNGVVEIAVFFDIEDLFLQGTRKFIKAIREIDAERGIQGFRGVVVFGEVWERIARREGGEEGRAVVLMLGWESLEAHLAFTKTQDFTDSTKYLKEGTGGVEMFHVSFRRAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8Y1</accession>
    <name>A0A5N6K8Y1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_001338</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8Y1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF45">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="1"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8299252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="397" mass="42585" checksum="DDE2C3118F86E6C1" modified="2020-04-22" version="1">MPAYILFGYNNAVAGGLLSLPAWIETFPQLDTSNVMGTQKDRNSRLQGTVVALYTLGCFLGALSCIRIGDTLGRKRTIMLGAGINIIGAILQSSSYSLGQLIVGRLVSGLGFGALTATAPNWQSECSKARHRGSVVLLEGLFISAGLATAAWVTFGMSYSIGGVTWRFPLALSILWSTIVLITTPYMPESPRWLIKKGRIEEAQEVIAALDDMPADSAQVQAEVVEIKDGHLIAGKSSFRDIFCMGDERLFHRACLAVCGQMFQQVSGINALAFYQATIFEGGLGLSAQTSRILSASVFTWQTLCSPIGVLTVDRFGRRKLMMFAAFGMGSCMAIIAGASSQISNTSCVVVAAVFIFMFSLFFPTGFLGLTFLYASEIAPLSVRVPITAMSTVLYTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8Z0</accession>
    <name>A0A5N6K8Z0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8Z0"/>
    <dbReference type="OrthoDB" id="406152at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="109" mass="12192" checksum="427C4ED9EFFC18A9" modified="2020-04-22" version="1">MCKYTFHQSSTCHQQHKDKDGPKAQARTQPCQWIQIAQPCACGTGLLNCPVFASNALRIDGPNIIRVKRKGCPRHDYGGLYDRNLVKMVEEVRTGGAVSFLFLMFFGMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8Z2</accession>
    <name>A0A5N6K8Z2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8Z2"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="112" mass="13353" checksum="EF5893528E18993F" modified="2020-04-22" version="1">MLYWEMANGIDWIGLDSRSGIGTGTRDQFEFNGRLQEKRINPSSLWLFYESRLEVLVEQYVLGDESTAQRNDKRNWWFKLMAKRLKTGTKTLNRREEEEEEEEEEITKVGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8Z3</accession>
    <name>A0A5N6K8Z3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001327</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8Z3"/>
    <dbReference type="OrthoDB" id="10256906at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034498">
        <property type="term" value="P:early endosome to Golgi transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055505">
        <property type="entry name" value="DUF7077"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045126">
        <property type="entry name" value="TRAPPC10/Trs130"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022233">
        <property type="entry name" value="TRAPPC10/Trs130_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251">
        <property type="entry name" value="EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251:SF3">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23274">
        <property type="entry name" value="DUF7077"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12584">
        <property type="entry name" value="TRAPPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24965">
        <property type="entry name" value="TRS130_4HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7077" evidence="2">
        <location>
            <begin position="31"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="TRAPPC10/Trs130 C-terminal" evidence="1">
        <location>
            <begin position="372"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8299237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="571" mass="63085" checksum="E0D4339F79B0CD26" modified="2020-04-22" version="1">MEYSYDNIGHLSTKGSDFFKCPRLLLYHRAEAFNARLFSSRCMYLDQNRSLEIELSSGWNNVTNGQLQIRAATAGLRLQTSEVTVIDGKVDIPKRPEAGVVHFGTMGSQTVARIRVPFNLEHEVNEVSLRLEISYTTKDGDFFFATTSSVSIMLPLGVNVQDLFKYKALFSKFTISTSTNSPLRLLSSKLEKSEMFEAQCGLGLTRPLTIFPRQPASLLYKISRTNSPPSPTARRKSSKPRTLSLILHYICLDEEVYDVVARVLEDFLRGNSLRPYTRLIIPVIISELRTHFLPYDFERAAILGEVPTSAILNIKWHDHFSGLGNSIEKDQDTAVIIGEILQEWQQKNPVIPLPLLSIDDDAISRSRSIVIPVDVPSVMVVHTADLRLLQTASIAASGAVAVANEPIPASLILRSTGNWDTASQDGITSSGEDLEFVYEVTGSSDTWLIGGRRKGHFKVPRVIHGRNHKLAFPIVLIPLREGFLPYPTVEIKALPITRSVRPGSSGGEEGVKSRSRPVTCETDCKNIGETIRIISDARKTTMSLDASGPQGGAWLLESERRPAGAGGIVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8Z5</accession>
    <name>A0A5N6K8Z5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable endonuclease LCL3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Probable endonuclease lcl3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_001291</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LCL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8Z5"/>
    <dbReference type="OrthoDB" id="238681at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TNase-like" evidence="11">
        <location>
            <begin position="79"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8299194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="246" mass="28541" checksum="6246D9E38F5FE026" modified="2020-04-22" version="1">MGWLDIFSKSKREKDDARSAFSWGDNLNSTDWQHYTDPRTLIPTILLTGTILVSARLYRSYLRRIPEAAYIRPGFFRKRSLFGTVTRVGDADNFHLFHTPGGRLAGWGWLPGRRSLPEGKDLKNKTIHPAQPFSAEALAWLKEYVHNRRVRAYIYRRDQYDRVVATVWVRRFLLRKDVGKEMLKAGMATVYEAKMGAEFGEFEAQYRAAEEQAKKKKLGMWSGKKRDFESPRDYKTRMAAAANPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8Z7</accession>
    <name>A0A5N6K8Z7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8Z7"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="121" mass="12896" checksum="07EB9FB3E6782E8E" modified="2020-04-22" version="1">MVSYARTKSNPCDRLPDLTDTYMSIWPMISAHKAERGCVAVIVDVDVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVKWMKKMKRMKKMKKMKKMKKMKKKNKVLLTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8Z9</accession>
    <name>A0A5N6K8Z9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001352</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8Z9"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8299268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="107" mass="11321" checksum="FDA55579686B5346" modified="2020-04-22" version="1">MSNKAFLWSKKCKEMSAHKAERGCVAVIVDVDVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVAVKWMKKMKRMKKMKKMKKMKKMKKKNKVLLTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K996</accession>
    <name>A0A5N6K996_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K996"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="124" mass="14449" checksum="C876D6911CE67903" modified="2020-04-22" version="1">MREEYRLRVKEKGFGRAFHALNEGREPKYVRELVAWINSDAELNGWQKIQGHSEAWLKEDEIKMGKLRERFEKRKQEQEREQEEKKLEIPGIYNLKSQGSLPNSSHLLFNGSGSHGKLEGQAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAH2</accession>
    <name>A0A5N6KAH2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAH2"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="127" mass="14779" checksum="15D266BCBB8276CA" modified="2020-04-22" version="1">MIPQQRHMNISLPLRLYFRLCNIQRKETSLEKDSHRSLDASPQQRQNIPSSPQPIPTLIRFSFSPTSPKSTKPYPTYPEFARSRDTNDKFYEGGAWRNEMIIFARFGRMVQLMDDALGTGRRNVSNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAI5</accession>
    <name>A0A5N6KAI5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LAGLIDADG endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAI5"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024856409" description="LAGLIDADG endonuclease" evidence="2">
        <location>
            <begin position="26"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="19038" checksum="ECDA19F9A6DCFC84" modified="2020-04-22" version="1">MLSCHLSLSSFVISRLLLIVRTVRSGYLLVSKRSTFYSDDICFTRSTVALTMQCLTDISIQHDNDNIDADFSRCRYVLPFSDSAHVQLVGSGNWETFDGLGALLVHGRKFHEGNSISNTSNNLCLRRKYSITNYTHANSILYCSPKSHSAPSRSLREPKSKTDPFHNGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAI9</accession>
    <name>A0A5N6KAI9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_000370</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAI9"/>
    <dbReference type="OrthoDB" id="449487at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.880">
        <property type="entry name" value="Alkyl sulfatase, dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="entry name" value="SCP2 sterol-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038536">
        <property type="entry name" value="Alkyl/aryl-sulf_dimr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029229">
        <property type="entry name" value="Alkyl_sulf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029228">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052195">
        <property type="entry name" value="Bact_Alkyl/Aryl-Sulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43223">
        <property type="entry name" value="ALKYL/ARYL-SULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43223:SF2">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14864">
        <property type="entry name" value="Alkyl_sulf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14863">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alkyl sulfatase dimerisation" evidence="4">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Alkyl sulfatase C-terminal" evidence="5">
        <location>
            <begin position="144"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8300141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="291" mass="31404" checksum="2DFCA8017BDA67AA" modified="2020-04-22" version="1">MPPTLSAKSNLRGYYGSISHNAKAVYDKYMGWFDGNPAYLWPLQPTDEATEFVTCMGGTDAVLSLAQGYITNNNLRFAATLLDKLVFATKSSDDPDSDIAKSAMSTLASVYTSLGYGSENGTWRNIYLTGAFELSNGPQPAFSSMAPEFLLSLSLDELFDTIAIVIEGPAAFQKPEVYLKKEITIDFMISDIIQDKKMGAAWHLRLSNAALTGHSIPYVQPSTSPNSGSDLTIWSDNINLVSLIGGAAAGKNPVIVDNPDITLTTAGDVDAWNKITSLIKLPNVKFNIVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAJ7</accession>
    <name>A0A5N6KAJ7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_000428</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAJ7"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005745">
        <property type="term" value="C:m-AAA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1690.20:FF:000003">
        <property type="entry name" value="Mitochondrial inner membrane AAA protease Yta12, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050928">
        <property type="entry name" value="ATP-dep_Zn_Metalloprotease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011546">
        <property type="entry name" value="Pept_M41_FtsH_extracell"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43655:SF2">
        <property type="entry name" value="AFG3 LIKE MATRIX AAA PEPTIDASE SUBUNIT 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43655">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06480">
        <property type="entry name" value="FtsH_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="445"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="23"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="196"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8300210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="646" mass="70534" checksum="CBB4D428CD483FB5" modified="2020-04-22" version="1">MTSILRQCSSLARISQTTIQSAARNSLRTSSTAPLLRSRIAAQRARAFATGPPKPDKDTQKDESEIESRKQKSSEPPSKSAPGTENLYDGKTPLSSSENGTEPTESPLVEGYVKLTDEEVKQLEQVIASMQFGKRQTTELKESLEVIKKTGVPSELRDLMREVKGRPLTLSEAARFTKLVLQMAWTAAKAQSQGTNFYSNAPKGSFDGNKGGQRGEQGSGKKDHKQEGFNFGNPSDMKLDTTTLLIGSFATYFLWQTLFPGNNKKDITFQEFRNNFFDKGLVKRLTVVNSQKVRVDLHTEAAAAMYPDSPAGNPNFHYYFSIGSADGFEQRMEQAQNELGIPSSERIPISYASDGDTWALIYTFGPTLLFIGAIFYMSRRASAGAGGNSGIFGMGKSRAKQFNHETDVKVKFKDVAGMDEAKLEIMEFVSFLKTPEQFQRLGAKIPRGAILSGPPGTGKTLLAKATAGESQVPFFSVSGSEFVEMFVGVGASRVRDLFSMARKSTPCIIFIDEIDAIGKSRGKSGGFSGGGNDEREATLNQILTEMDGFNTTEQIVVLAGTNRPDVLDKALMRPGRFDRHISIDRPTMDGRKQIFKVHLGKIVTNENIEYLTGRLSALTPGFSGADIANCVNEAALIGQICCHVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAK0</accession>
    <name>A0A5N6KAK0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_000418</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAK0"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8300195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="73" mass="8571" checksum="E4E7024ED7C8A7EE" modified="2020-04-22" version="1">MHHPNNGKTFHLLLNLYPRSYDFLFLPLHPNTNDKFYEGGAWRNEMIIFARFGRMVQLMDDALGTGRRNVSNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCL0</accession>
    <name>A0A5N6KCL0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GYF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCL0"/>
    <dbReference type="OrthoDB" id="331341at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039905">
        <property type="entry name" value="CD2BP2/Lin1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13138:SF3">
        <property type="entry name" value="CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13138">
        <property type="entry name" value="PROTEIN LIN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="448" mass="49872" checksum="A3DD7E8190DF41D2" modified="2020-04-22" version="1">MSSKYAAARPKRAGEEFARSHRNENEDGPSKKPKFDLRNPSALVADEPDEDAVLDADVIGSRGTGTKRGAVNIDGYDSDSDNEGFDARADERARGKKGEVNLAEALDEYSKEKSGSTNGKVDIEDDDADMFADLEDEFAGGDENESELKARKKGKEVRFLKEDEIEGQVLGSKSGGHISGNFALDPKGKLSTHAMDDQESSDDEEDAVLAAQEEDVDEEVGAGGLKRNAPKVDAFNMKAEQEEGKFDANGNFVRNAADRDAVHDSWLEGISKKEMKKAAEAHEKREEERRQKRLEDDAMLLSDILRTLILRLDKGETVLEALARLGKGQAKSKKIPRWKLKKQLRKDDSMDVDSGKAEDPEQIRIREAINAITGAADQLLIRGQTDVYEQEREMLVRQYRRETGEEWAEPPREADMDEDGSTKAIKMWEYRWTDGRDGAAKQGPFDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCL3</accession>
    <name>A0A5N6KCL3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FCP1 homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCL3"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000089">
        <property type="entry name" value="NIF domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="223"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8301156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="415" mass="46360" checksum="24582200056975E3" modified="2020-04-22" version="1">MNSLNILSGRGSPTHSPSLSRSNSLSLSRSNSLGNVLASATISESRRNSREGLYNEKLETLDQEGAPDSNPGDGKSIHECTPLLDKEGTTYHTSEHTGIARMFYDSIRETEDPATKMPNRQTRSKSLQSSDEISPARRSIRIKLHSDENLRQRKHRKSQSTTTQSDGSGGSMSATEMTAAIMKSPTSPATSSLLMTKYPRAPAPPRPLIPRRQPSYTLDAPAGKLTQKTLILDLDETLIHSMFHGGRMSTGHMVEVQITNVVGSGPVGPQHPILYYVNKRPYCDEFLRRVCKWYNLVVFTASLQDYADPVIDWLEQERKFFSARYYRQHCTFRNGGYIKDLSSVEPDLSKVMILDNSPTSYLFHQDNAIPIEGWINDPTDNDLLQLVPLLEGLQYVTDVRAFLALRGGEDGKHMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCL8</accession>
    <name>A0A5N6KCL8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AMP-binding enzyme C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_003019</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCL8"/>
    <dbReference type="OrthoDB" id="3633556at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF5">
        <property type="entry name" value="MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="3">
        <location>
            <begin position="3"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8301115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="71" mass="7960" checksum="58653D3AA12DB69D" modified="2020-04-22" version="1">MYGQDVGVAIVLKPDQKLTASDLKKWVADKVAKFKVPKQVFFTDVMPKTATGKIQRRIVADTMLKQPKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCL9</accession>
    <name>A0A5N6KCL9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Monothiol glutaredoxin-5, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_003050</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCL9"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000005">
        <property type="entry name" value="Glutaredoxin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00365">
        <property type="entry name" value="Grx4 family monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF16">
        <property type="entry name" value="GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="7">
        <location>
            <begin position="49"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00067618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8301151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="146" mass="16068" checksum="B65A581D45166F1A" modified="2020-04-22" version="1">MISSVFRQAARPATFASKFSVPRFSPIASRYLSTEVRKQIDAVVSSKPVVLFMKGTPESPMCGFSKATIQILSLQGLDPEKFAALNVLEDEGLRQGIKEYSEWPTIPQLYVNKEFIGGCDILIGMHQSGELAKVLEENKVLVEASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCS0</accession>
    <name>A0A5N6KCS0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Selenoprotein O</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_003099</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCS0"/>
    <dbReference type="OrthoDB" id="10254721at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070733">
        <property type="term" value="F:AMPylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00692">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003846">
        <property type="entry name" value="SelO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057">
        <property type="entry name" value="PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057:SF14">
        <property type="entry name" value="PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02696">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8301208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="648" mass="73225" checksum="509DBED72CFF2E49" modified="2020-04-22" version="1">MLPKPLSKPCWPPIQLRIRIAQMASHLSPGNASKSSSYIGTGTSLADLPKSWTFTSSLPPDPAFPTPAVSHKTDRDDIVPRQVRGALFTWVRPEETKDPELLAVSPTAMKDLGIKEGDEYTDEFKKTVAGNKLLGWDEEKFEGGYPWAQCYGGFQFGSWAGQLGDGRAISLFETMNPNTSVRYELQLKGAGITPYSRFADGKAVLRSSIREFVVSEALNGLKIPTTRALSLSLLPHSKVRRETLEPGAIVARFAESWLRIGTFDILRARGERGLLRQLCTYIAENVFQGWESLPARNPADDGKVDTIERGVSKDTIEGPAGLEENRFTRLYREIVRRNAKTVAAWQAYAFTNGVLNTDNTSIFGLSIDFGPFAFLDNFDPNYTPNHDDHMLRYSYRNQPTIIWWNLVRLGESLGELIGAGPDVDNTVFIEKGVREEDADEVVSRAEAVITRVGEEYKSTFLTEYQRLMTARLGLKVFRESDFETLYSELLDTMQSLELDFNQFFRKLSSIPISSLETSSSRKEVSTQFFHREGVTGLNNTLESATARLSDWLEKWQGRIYEDWGPDGDDENRMTEMKKVNPKFIPKGWVLDEIIKRVDKGGEREVLNRVMKMVSDPFRESWDGDREEEERWCGDVPRGDRAMQCSCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCS2</accession>
    <name>A0A5N6KCS2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_003061</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCS2"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF30">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8301164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="417" mass="47196" checksum="9691B91F8BC3634B" modified="2020-04-22" version="1">MQAISLTEIFTRFRGKKTTVRISRQFEDLYDRLLNPSYPNSETETTPINTSTPKDLTNHFNTRTRSEDIQSNWLLWVETESRQRLSCLCFIFDIQQSMYHQQKRTKPYVDPTILYTPCSEVVWELTNAADWATNETGNSTGKTINVVQHQSTQEDQLELSHFAQSVMICFLTSQLPLPAGPDCYYSSEFQIHNPHPTILELVTLFPASSMVNTYLALYHTPLRDLLAVSGDTWVFSQKISHQSHFHEAQSRLKAWSSSPAAATATHHACRILRSEFSAPCSPFSVHNKNLPSLDLANYWSLNVAALICWAFGHRVGGSNGTSLQNTLDIYADLDFETSPEASENMRTEALTYLDSMLELDVKDLLTSKATMRGETHCIIDAVRTKLEIDSLGSHCMALVDSIGVLRRIREGGRGKWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCT0</accession>
    <name>A0A5N6KCT0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_003107</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCT0"/>
    <dbReference type="OrthoDB" id="434258at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02639">
        <property type="entry name" value="R3H_RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12253">
        <property type="entry name" value="RRM_PIN4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.50:FF:000002">
        <property type="entry name" value="Immunoglobulin mu DNA-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000743">
        <property type="entry name" value="Similar to R3H domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034186">
        <property type="entry name" value="PIN4-like_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034069">
        <property type="entry name" value="R3H_Cip2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF17">
        <property type="entry name" value="RNA-BINDING PROTEIN PIN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="167"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="R3H" evidence="11">
        <location>
            <begin position="321"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="100"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="527"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8301218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="604" mass="66607" checksum="255295301B302640" modified="2020-04-22" version="1">MMSQQYSEMFQDYPPNRSPATSRGYGNMTLNRQTSRQFMDNYQAPLQSGGGLYASEDAPQFNGNQAGYRGPSNNINYAYESQTWNYGGANGASTMGAAGRMRPQQQARRAEIPSGWMNSGSPSLGGPITQSSLQQHNLSGMFEQPQHSHRSPPPPNQQNDHEELIPTAIVIKNIPFAVKKEQLTEMMSNMGLPLPYAFNYHFDNGVFRGLAFANFTDARETQQVIDALNHMDLQGRKLRVEYKKMLPAAERDRIERDKRERRGQLEEQHRAPNMISTGSLHTAGSMTSMNSGLRTTSPSPVNMRQTVVTPNSTAAEYDLNDPTTLSYYTELLLFKNDPEREAFTFAPTVSPADRRIIHTLAHNMGLDHHSQGHGELRQVQIVKTKHASPPMSQMQAGYYNESQRRGLNRAATIDFSEQRANDAAYQMHTLGRQGSGLLDIPGSPGNIARFQGNDYGLGSTTGGTPNLTPTSAGPLGLREDTFLANGISNMSLGYDRQPRSNVPGRIGQERDSYTSTAAPEVARVQFPRDNPEDRPAINGARDSPATDKAAMPAKAVMIHPSEPAIPPLLGSCNNLHEIYDVTNIRATDAIYSYVSQRHTTVSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KER5</accession>
    <name>A0A5N6KER5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005572</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KER5"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="87" mass="9988" checksum="B6ED76FFA4AA9B72" modified="2020-04-22" version="1">MYKELKLGSRSRVDSPVEMVKCDRPVGRKIYWVSIQSIQKIHLSQTLSYCQSGAQTLSNSTNVLMWATSNINYPDFIQHPQILFSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KER7</accession>
    <name>A0A5N6KER7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_005668</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KER7"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="268"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="381"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="385"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="399"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="428"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8302224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="557" mass="61772" checksum="9F9DE5693B4B7DDC" modified="2020-04-22" version="1">MGNENEPDFPLFPEANMYSPQYPYNGIPNFHIDHDASYAYPRTQDVYPTSTGFDSTTMYSEVPQNFIESPELRGAAPSNYSTASGPSATSSTIGSPNSNNGHIVSVSEWGSGLGINPSIVNYDNFGQGTDYNFSTDPSILHAPFSTTRPTSAIGQSELSPYQAPMYPTSPSLSQLSSRSPGPAKTGSASPYLGSQYYPYPPPMVRRPSLTISHQSYGSQDGTFSGEDAKEKGRCTWPECGKVFKDLKAHMLTHQNERPEKCPIQTWTMVCGFCPGSGSAAEKSFNRADVFKRHLTSVHAVEQTPPNSRKKTSANINSGKKLSGYAPDATGKCSTCSATFSNAQDFYEHLDDCVLRIVQQEEPSEAINARRLAEVEQDHDVHETLRNNALPVTTNVYSTAEDDDEEEVDDENDDDYSLRVHTSRKGRQNRNPPNGVQKSRGMTHSKGGVTLNTKGRKKRKDYPSSWGCPTSQMKMKKRVLTVFDGPRRLWKDDMMLDTDFEVRIKLGDEKAYVTDLDVQTMGRAEAFHNATEEEKGPWIADDLTGMDLEKLMEVKREM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF10</accession>
    <name>A0A5N6KF10_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF10"/>
    <dbReference type="OrthoDB" id="3558403at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="406"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="508"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="751"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="326"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="508"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="525"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="539"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="554"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="570"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8301582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="798" mass="89207" checksum="F3353CD52684A462" modified="2020-04-22" version="1">MTDRKRRPGRKPRETTRLGNTSGNPTTPSTPPEDLSSTIQDPDAPPRRPEASGALRGPELPRTAEGERDFSSMGRAEPQGADDARPARRRGFVPVREPSPPAPRFDLAPFRRDGSYDMQAIMVGGGEGGGRQAVVEFVGEVRRGGGGGGGEKKVAGGGGVDDVDEDDFYGASPVRPGPSNVLPAQKEDEKRKGKEKEQEKRPQDKKSDIAFGKPKSPKASPVKEQSSLWSKLFSRAQKTSPTKSEKYRKLAANETAQLTEKEKFDYWMKHELSSPRAVVADENEWQKEMELLYAREKHIAQLQQAKADASAMISQGDKESHERQELEEMISQCDLHLLEAEELEDKRQWRRSLQTSLGLETSPTFLAKFNDQLRDLNAKIEDDEKKERLRLKPWVDVSPDWAARLQKASDMTPSERAASSAGRGLHAPARPPGQLKQSSAEKALRVKWATEDSPHENELLEIQTYSDEMERDVAWGLAMRKRQSVLLARHKELSDLWTKQAEEMRADRESAWLESTGEKRIPISEPQSRAASMQQSKGLGEGTGGSGAGQYDILSDKQKQEKKDEEDEKNEMAREEAEGSKKMSRAEMKNAGRLGERRAGRQGIFNTSGLRQMPEMEPGPSSMRKRSMDVIPNPSETPASRSRKSTTPERPLSPFRATKAISPLQEGRQKPVFHVDSEVSEYLESLTQCRIRLEMQKKGVEMVDLDVMRKLVGTVAKPIVISVEGAAEDVAAMERRATRIREAKERLALAAKGEVERLREDEEKKRKKEEKEKEQGEGTEEAKDRVGTEEEGRGRYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF26</accession>
    <name>A0A5N6KF26_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sterol regulatory element-binding protein 1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF26"/>
    <dbReference type="OrthoDB" id="2133190at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032933">
        <property type="term" value="P:SREBP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019006">
        <property type="entry name" value="Sre1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09427">
        <property type="entry name" value="DUF2014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sterol regulatory element-binding protein 1 C-terminal" evidence="1">
        <location>
            <begin position="178"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="629" mass="68536" checksum="DE1C5B61AEF2B3E6" modified="2020-04-22" version="1">MGFGPIQQPMNPYQYAQEFNTPGPSPSSDQGMIPVPDDMRRLHGQMNQEAFAVPTQYLNQNRQPIGPNAWNGGYFGKLMVGSLAGLMIMQGFSEAEQEPDTPGARGLMALPAQFLRTVSRGVHSALEVNFQGYHLAAHQTVHYLQCSLALGLLLYIFLPSLFRPKPNSKDSKSAHLAAAPSLASSIQVRRQAWLTAIQTVWVPRHNFFLEAAALCMKVGKYTCRNVVGPSLYSFLTGATEEQEVARIKAWSIALDAQLTGGDVEVSKSRLTLTLLASGTLPDTPARLMLKALHIRVLLWEPKSNGFSGSNIVRNFAQEMARWKWNEAKQMQQILSQSKEQHDELPEYLATLLEKNCDDVLVDAVVQRAYNLAWNLPTTNNTHVNCGMDRVVDDFAIRSPLDAVAAWWSSLTLHTALAKSLEAKDGDVESYKTVVDGIKMAIQTAPPGSGAQIRALAARAVLVKEQRGHSIAIALKAVGAGQQKMPAASNVNIKTSISNLPDIQSSVHCAMALAYLERFPMPAHPENAVRIIDSIVPSNLTLLGFTSLFKLLERMHEHTSISSACALSVEKFAGGLRIWIGGPKGAKSGLDTELKNEMVDKFKAIIAQAVGMENDAGYGTMSGDDDSEGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF33</accession>
    <name>A0A5N6KF33_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF33"/>
    <dbReference type="OrthoDB" id="5342184at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="97" mass="10662" checksum="FE34BCA6FCF6077E" modified="2020-04-22" version="1">MDRGRLACLMHSVPDSLMTTYSDVTSELQKLKPLVGTFFITSQATALYTSLGDHWEHVGIVLVSTFRAPLSCFETGFCGSIEGLLEPVILLLAFLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF35</accession>
    <name>A0A5N6KF35_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Suppressor of forked domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_005724</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PRP39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF35"/>
    <dbReference type="OrthoDB" id="10265668at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000243">
        <property type="term" value="C:commitment complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030627">
        <property type="term" value="F:pre-mRNA 5'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000395">
        <property type="term" value="P:mRNA 5'-splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000451">
        <property type="entry name" value="mRNA splicing protein (Prp39), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000064">
        <property type="entry name" value="Putative pre-mrna-processing factor 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059164">
        <property type="entry name" value="HAT_PRP39_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204">
        <property type="entry name" value="PRE-MRNA PROCESSING PROTEIN PRP39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204:SF5">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23241">
        <property type="entry name" value="HAT_PRP39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23240">
        <property type="entry name" value="HAT_PRP39_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8302285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="68962" checksum="3519BFA8AE79C0FE" modified="2020-04-22" version="1">MADFQYGGTDEESAEIKKLNAEVLEDTDNFESWEKLVRAAETLEGGLNRNSSPQAIATTRDSYDRFLAKFPLLFGYWKKYADLEFSIAGTEAAEMVFERGIASIATSVDLWTDYCSFKVETSHDPDVIRELFERGAVAVGLDFLAHPFWDKYLEFEDRVEAQDKIFAILNRVVKIPMHQYARYFERFRQLAHARPLTELLPAETLEQFRADVVSESAGFQAGPKGELEIERDIRTKVDNFHLEIFARTQAETTKRWTYESEIKRPYFHVTELDNQQLANWRKYLDFEEAEDDYTRAVFLYERCLVTCAFYDEFWFRYARWMSSKERKEEEVRNIYQRASTLYVPISRPGIRLQYAYFEEMSGRVDVARDIHQAILDRMPGHVETIISWANLERRQKGLEAAIEVYKAQIDSPAVDIYSKAAFVAEWAALLWKIRGSVDEARQVFQKNKQWYPESRHFWTKYVEFELAQPTNSGSESEHYERLKQINGEMIKTHMRLETKKEISNLYLTYLQERGTKEAMKEFLQIDRELNGPISVQPDHVKAAESGKPTENGAIPGAVDAASLLKGEVRYNTYFQQRKHQLPADAQGLASFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF38</accession>
    <name>A0A5N6KF38_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_005793</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I LYR family. SDHAF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF38"/>
    <dbReference type="OrthoDB" id="3554803at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20268">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045295">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF1">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="5">
        <location>
            <begin position="9"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8302364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="78" mass="9163" checksum="497E10C444897DEC" modified="2020-04-22" version="1">MARLSGLQREVLALYRKCLRESRKKPAEARSHFEAFARVEFDKNISLDKKDFSAIEYLLRKGQRQVDMYSSPGIKDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF46</accession>
    <name>A0A5N6KF46_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF46"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="108" mass="11826" checksum="10714DCA0A28DD2B" modified="2020-04-22" version="1">MPCYSICQDKNSSSSQALGLWPENIGFKLRSNTNKPFEYQSRSKQQAQHHTSQTPNKKSTCLHALAALTPPLKAAQALAPAARTSTDNLIASLHIISHISNLFTASHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF85</accession>
    <name>A0A5N6KF85_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_005766</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF85"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF9">
        <property type="entry name" value="TAH-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="4">
        <location>
            <begin position="62"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8302335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="396" mass="44542" checksum="FCA8A1769E6C82F1" modified="2020-04-22" version="1">MIAIGAQSRGKDLLEIQVAKKYFAQAQQMAFLGMLESPSLSMVKLFLLMAMYMLGACRRNTAFMYLAIASKSATILGLHVPYQHSWVSSEERAARRRIWMSSRVLDLLCSAILARPSSTPSIERDEYEIDSSNPEDLDHRTLALYATYESSSIIETIVKKFAKSSSVDIQSADTYLQMLREWSHALPSALRNVPGPASESDYGESAHLMVELCYEAYLSDILLGNMCILKAWIFSAGLVLGFSLLVESKIPTHINECFDHSCILLKKLARLSPQAEQYHDILCRFRTAIDLYRQQFLKALQENNNKYVEKIMTIGSFNRAPREGNSSTELQSQLQLVPTTEQPIFEELEGQGCFAETYATDFFGLENEIQMYDAQIGYDTGVAADLRWLCYAAGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGT1</accession>
    <name>A0A5N6KGT1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGT1"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="117" mass="13799" checksum="3E7E92F7E32C58FE" modified="2020-04-22" version="1">MVRPAYFGRFQDTMVILFSIWYSPGSKFCVLPWRMLKMRHLQWARCTWSEISGYTSAISLPWALAVVKTQPGFNVLDYCIHIIPIEVYLGNYKKTLSDIPMINFYTIMYVCMYVCMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGU0</accession>
    <name>A0A5N6KGU0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8303000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGU0"/>
    <dbReference type="OrthoDB" id="10261782at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038921">
        <property type="entry name" value="YOR389W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204:SF1">
        <property type="entry name" value="ENTEROTOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204">
        <property type="entry name" value="YALI0A21131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="556" mass="62681" checksum="AEEE0FD7E0B44250" modified="2020-04-22" version="1">MLHIYGNVTGPDPNGHFGPGLVSVEEVGELKDFLILVEHLNVTAPLLPENKLEDIYEEAAEDMASSLPRLSTKTQPPKATQTKNSTENDPALPPNFRNDGHREPFLRNQGWGWFTSAVTHYESSEEGPGLGENRVKLLARGILSYYSPKFENQAISRAVIERGTLNLTGEGFWMRVLDDEDSRATALNALMRRRRSYTLDDVSTDEAAIMKEDSERVLETLMGQPVNCSDIDWTAMTNEIVRTYASPLAQLLHSLRNYSSIPPSNRSAQRKWLSSIRDQTHSLLLPFLEYPSPEENPSIWTRQSPLFQTTHSNCHHHHTRLLSSPNIPLFPEERTLESAIEETQGQICNIIISIGFSIENIWNSSFNQPSTNSNDNPASPLEKNTKEFTRWIHGIEELMAWLGWACEWTSWGEGPARRPPPRYGYGPGKEHGPGYRHGSGYGYGGPPGRGDHNPPAGGDHPGRPSWRIDETDLWQPRCVGLEYIMGCSHIMSSREVPKLLDDQKGLEVRQLREAWVLYGIGIDDLVDIHRFSDLKGDVIVPVPRQEHKTIRSMTQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGU9</accession>
    <name>A0A5N6KGU9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetylglucosamine-induced protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGU9"/>
    <dbReference type="OrthoDB" id="10053431at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022036">
        <property type="entry name" value="DUF3605"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020:SF4">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12239">
        <property type="entry name" value="DUF3605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="26086" checksum="D18C5E5FE75EC907" modified="2020-04-22" version="1">MGSITPSPPYWQTNIPPSSHTATCPNFLQNLSPKDISILSTPDPEYHILTWPSVRQIIDANRLDLFQRKPSDLRRYLEYCYTIKSQHGSVMRYILDVKLQWKEEEIAAGAKKVSFADENNLKVLLNDWPYGIDEKIVHLVVWTKFALEDDPETGDTREDVKREIDGWVDEVFGKRCGSENVIWFRNWRSLKSVHAVEHFHIMLYNPDPEFVKKVTKGDVPNQGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KH61</accession>
    <name>A0A5N6KH61_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KH61"/>
    <dbReference type="OrthoDB" id="3545168at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="363" mass="40174" checksum="77B5C7C28B8933EC" modified="2020-04-22" version="1">MQRTGYDPTMEIREGRGSRQSSLHIVTDNSDDSSGSDYSQEDGMNLPIAQRSQSIGSVPVSPMQDDEIPVQSSKYNSSNVSSQGCSTPKSLVISPEYKERVSRFMRGHLGEPNNNRGSHYSESLDDLTDQERVRYEYQSTGGNLLENGVHNDDRALMPPPLAMPIKKSRQSYFSESPEDWEPRTPTTPFLTSEKDQNMHDGPSTVSSTPSMAPPNLITPEPKKNRKRDFSSGNHPLKSPFPFLSPSKTSDSPKSAGSLGEKFSDALKRLSFTRTSPVDRNEVISNTSRSPTGPDTPMPKKSGFMGIKGTPDVIQKGNEHFHEVLEKAKLSVSKKERGRKELKKQIVVVGVMDQTPDGKASEWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KH70</accession>
    <name>A0A5N6KH70_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KH70"/>
    <dbReference type="OrthoDB" id="8117402at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="204" mass="22630" checksum="310C0CE8DB113335" modified="2020-04-22" version="1">MDTQRGRSPSGGHQHIRNHSPSPQTFQDGMNGLGIALDPSNINNHQQFQDNFNNPNTLPTYVETNEFLNQGQQFTQSELGETNFATSQTQDFSQFKQEDQSSFAPPQRSFIQELLSDNFDGDFSLYPNTSGQNEQFDQSFFMNDLSPQPGNSSINPAELNMSSPVHTPTPPSLLQPGSRSPSSAQQSPSFNQGPFQPSPLYRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KH75</accession>
    <name>A0A5N6KH75_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8303008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KH75"/>
    <dbReference type="OrthoDB" id="3549727at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="559" mass="62133" checksum="C693B7F6A508662B" modified="2020-04-22" version="1">MTNGGLNAQTVGGHMADRKKMFRDQPRAIRNQKDDLERLRAVSDIRCRPWVGDKMLLMQANNTTHAKVKNHFEERARQEAKQAIKAGGQVLLDFEEVRDKRDTSSRYATKMWADYKHNKEEYLKSLRNGLISLKTGESIKGDLNMYMYSALNPANGHIQSAGSGNTAGKGVAKLAGGRDDLLRRSMEDTPNTIDKYSSTAEPCQHPTRKREPFRSSNDQAENSANKKSLEQTRGSIDSINSGMTFHNNPFGGGESSDGYFGKSPDFCNDRLGARIPSAVDQQFHQPKAHTKSMHIGSQPSNRVDQSSEIGGVSLGGNGWNDRQKEASIAYEGKSVKPLGSQADGFELAENSTQMAFAISSKKRKESLLEEETMERRPLKKQCQLEGPLQPEQQPEHDQLQPRIRYSGLDFEGNTGEGHVQELDHVPEEFAEWNRHVMQDSASLPVQPHIQGTSNRGEFGVSNNASYLESSLWIGFITNRENLPLNEENNLPGSKSENAIPVPDGKGDAETVRESQRIGGQTSFNGKQPLKEEDEPGYLAGASCVKGYTNAWYFQGRLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KH81</accession>
    <name>A0A5N6KH81_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KH81"/>
    <dbReference type="OrthoDB" id="18320at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="114" mass="12530" checksum="D619EAFFCA1E6218" modified="2020-04-22" version="1">MTTIPSIACLGVIGKNIFKAMQAAYIRLLQNPFYDPDEHCPVNGKGGKKIVSRLFNEDMRRIGEGWVPGSGFALWKRKGEFCLYGERHDTGTGMGVGVGVGNLYAEHLTRKKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIY0</accession>
    <name>A0A5N6KIY0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aromatic amino acid beta-eliminating lyase/threonine aldolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_004957</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIY0"/>
    <dbReference type="OrthoDB" id="10261951at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008732">
        <property type="term" value="F:L-allo-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06502">
        <property type="entry name" value="TA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000030">
        <property type="entry name" value="Low-specificity L-threonine aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000089">
        <property type="entry name" value="Threonine aldolase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041359">
        <property type="entry name" value="GntG_guanitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="7">
        <location>
            <begin position="44"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8303551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="406" mass="43383" checksum="D4DAF5949EA242F0" modified="2020-04-22" version="1">MAAKGKDLGTDDLKGLGGTTDLSPTPEPHHEINAWSGPGQAAFDFRSDVVTTPTKSMLTAIQNTTLFDDVFAEDPTTNSLESYLAQITEHESAIFVLSGTMGNQIALRSHLIQPPYSVLCDHRAHILEWEAGGTASLCGALVKGVVPSNGVYLTLKDVEKYVTISDDIHSCPTRVISLENTLAGTIMPLEEVKAIAGFARKHGIKLHMDGARLWEAVVAGAGSLTDFTRECDSVSLCFSKGLGAPVGSMLVGKKAFIKHARWVRKSIGGGLRQAGVLTAAARVAVDETFGKGPNGEGGLLRESHKTAKKIATLWEGLGGKLQQPTETNMVWLDLEDAGISAKEFSALGKEKGLKLLAGRLVVHYQIGEEAVAKLGEIMKVILERKGKGSIEVANKRRNIGEKDYGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIY5</accession>
    <name>A0A5N6KIY5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CTLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_005129</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIY5"/>
    <dbReference type="OrthoDB" id="972532at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051350">
        <property type="entry name" value="WD_repeat-ST_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838">
        <property type="entry name" value="WD REPEAT PROTEIN 26-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23627">
        <property type="entry name" value="LisH_WDR26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CTLH" evidence="6">
        <location>
            <begin position="375"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="560"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="602"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="825"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="142"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="174"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="246"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="281"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8303746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="867" mass="96215" checksum="90B3AE7FE4D07B07" modified="2020-04-22" version="1">MVHLTRSHFHSYIDYGLVLLLLCREVLVATRYLRSNGVGMDVLVPTYLPTTNPYLSCLITHNLSVIFHITSYMKYLRVLYLWLDDSFSFSKNIPTLIRSIRLLQRMSFVDRLLCGSSLPLQYNTVSSTPNLLQLVSGTPAEDVLAGENPQDSVSLSTPDDPSTPTSLPRPTSTAFSAQLRSPQYQHATEQVNPLPTSGIHSIEPTGITDTRTRSTPQAELRPPRRAPDQVLGRRRRTHNLDRGEQSNSLPSLGDSPDPSNSESEHRRKRKRQSDSMRFDGESSNSNGNSKPISNGAGTSLHKAALSNSANGAHSSSVAMNGSSTNGHSDLSIKSSSTYFGHDREEVTRILVQALTDMGYNSAATTLSRESGYDLESPTVAAFRSAVLQGEWAEAEELLFGASTELGGLSVYGNGLVLREGTDKNFMRFWMRQQKFLELLERKELGRAINVLRSELTPLYQDTAKLHFLSSLLMCTPEDLKAKANWDGATGKSRQLLLSKLSKCISPSAMLPEHRLATLFDQVKQHQISSCIYHNTYTSPSLYQDHTCDRGNFPLRPAIELDKHSGEIWDTKFSHDGTLLASCGSDGVIVVYNVPDFDVHLVLSEHEAGVCSFAWSLDDTRMVTCGRDNRACLWNTATGELLKRLPRFSEPVTCCVWTPDGQSFITGSLSSDKNLCQWNLDGDLIHDWSRNHRIRDIVITPNGHRLVAIAHTSQLYVYNFVTRELEYNIDLKVTGCSISISQNSRHLLVHFNTGETRMMDIETGEKVRSFISGDKGGDFIIRTTFGGANECFVVSGSEEGNIVIYHRENGSVIEKLEGHKKGCCNSISWNPTNPSMFASAGDDGIIRIWLSENAPRKVPISQSGINGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIZ4</accession>
    <name>A0A5N6KIZ4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_005063</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIZ4"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF396">
        <property type="entry name" value="FLOCCULATION SUPPRESSION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="109"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="306"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="427"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="315"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="391"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="402"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="427"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8303672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="513" mass="56796" checksum="53B02CDFCBA1C652" modified="2020-04-22" version="1">MSAMMDLTDDRVQHHSYINGPNLAQNPARTVPIIQQPILQTSAPPGEAMDVASPGTVIMGPPSITSPDNEANGIQDHMIGGDQPISGSLGTPSAAAAAAAGGIGQPKVVQTAFIHKLYNMLEDNTIRHLISWSATHDSFVMSPNSDFAKVLSDVFHQNAPDTPLWEFKHGLNSFKRGDLVGLREIKRRASRQSLVHRDSYSAPKPPLSLPGTPAEPIQSIQESTESRLTQLEHTLYDMHGRLAKNDETTHSFHVRNQIVMDTLTRVLQMNHDMSRMMLSLTSPESPLHRDVIAMQGDIQRQIETVRGMEDPNEPPFSNTRPYFSNLTLDNPPSPRQVPQDDTRRSSFLGVPPRQNFHRPPVPSNLSFSSRRGYGSIGGAVGWQATSSPFASGQSSSHYPSSPKRTATQMMSEDQRIRDSFSLYSLTGASQGHNMSRPTTPPYTNGNTAEHLNSWSWAGSRDRGPSSLFRDNSGPPTRRGSMAHILNPAETAEREEEHEEEMLREEDRKRKRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIZ7</accession>
    <name>A0A5N6KIZ7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Opsin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_005142</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2020-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Rodriguez Pires S."/>
                <person name="Melgarejo P."/>
                <person name="De Cal A."/>
                <person name="Espeso E.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">8L</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="journal article" date="2021" name="J Fungi (Basel)" volume="7" first="0" last="32">
            <title>Light-Photoreceptors and Proteins Related to Monilinia laxa Photoresponses.</title>
            <authorList>
                <person name="Rodriguez-Pires S."/>
                <person name="Espeso E.A."/>
                <person name="Rasiukeviciute N."/>
                <person name="Melgarejo P."/>
                <person name="De Cal A."/>
            </authorList>
            <dbReference type="PubMed" id="33430380"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">8L</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <dbReference type="EMBL" id="BK014385">
        <property type="protein sequence ID" value="DAZ85342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIZ7"/>
    <dbReference type="OrthoDB" id="10261467at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15028">
        <property type="entry name" value="7tm_Opsin-1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000160">
        <property type="entry name" value="Related to Opsin-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018229">
        <property type="entry name" value="Rhodopsin_retinal_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286:SF2">
        <property type="entry name" value="BACTERIORHODOPSIN _OPSIN, NOPA (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00950">
        <property type="entry name" value="BACTERIAL_OPSIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00327">
        <property type="entry name" value="BACTERIAL_OPSIN_RET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="DAZ85342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8303763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="310" mass="34103" checksum="5F095BBE200DC5AC" modified="2020-04-22" version="1">MLDPMQAFDMEGFRTATSSLLVPTTSPTPSVSPIPTVVPSVPTYETIGQPGKNTLWVVFVIMFLSTLTFFYLAWRVPVQKRLFHVITAFITLFATLSYYAMAVGDGNALTHIVLREAHNHTPDTFEHIYRQVFWARYVDWSLTTPLLLLDLSFLAGLNGANILVTVVADLVMVLTGLFAAYHNDGAAKWGWYAMGCVAFLVIIYQLAIPGRRAVSSKDAKTSKLFAAIAGYTLIIWTLYPIVWGIGDGSRTWSVDSEVIAYAVLDVLAKPVFGLWLLFAHGNNAATSVDGWWSHGLSSEGSIRIDDDDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJ99</accession>
    <name>A0A5N6KJ99_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MINDY deubiquitinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_005235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJ99"/>
    <dbReference type="OrthoDB" id="10261212at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016807">
        <property type="term" value="F:cysteine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990380">
        <property type="term" value="F:K48-linked deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007518">
        <property type="entry name" value="MINDY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033979">
        <property type="entry name" value="MINDY_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18063">
        <property type="entry name" value="NF-E2 INDUCIBLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18063:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04424">
        <property type="entry name" value="MINDY_DUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MINDY deubiquitinase" evidence="2">
        <location>
            <begin position="374"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8303866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="671" mass="73995" checksum="E93E6D0DE8E9BC25" modified="2020-04-22" version="1">MTVTRKPVPQYTNPSNNSSSPPYPIAPVVTNSQTSFRIEDHNNAMFSANNSGSNIWKEGEDSHSNPGSLPDSLKVGPSRVTPRPSQDMLNPNLSTTNPFLRRKQSQISQSAVSDGKESSADIWNELTETPTRPDYTPPSPPVSQVTQNFSNMEVSEQNTNPWQPLLKEKQSTQTFNFQREDSGNEAWSSANPQKAITPPDLPDKSRQPVLVDVDEPESPAWDEDGYDEEESEEKIPASPKKSSLPTHEAHEVAEDQHARDIAHDQQSIQAQRIPIPHSGHAQYPSPPAEGWNLIDHEAIPDNVQQSGVIGIDGVEISRSPSEEDPPALPPRNFQERPSLPPLQPPRPNVDAANRSTPSIARPGTSASAQRHKKETYEIKKISWHDVNAQHNPRVSPILVQNANGPCPLLALVNALILSTPAGLETSLVETLRSREQVSLGLLLDAVFDELMSGRRGDAAQDLPDVSDLYSFLLALHTGMNVNPLFFPTMPTQSANDPRNSMSHIHPAQREGSVPGTFEETREMKLYGTFSIPLIHGWLPEEESPAYMALKRSARSYEDAQNLMFHEEVLEDKLATEGLSFQEQGILEDIATIKAFFASAATQLTTHGLGLITTSISPGAVAILFRNDHFSTIFRHPTTFQLLQLVTDSGYAGHEEVIFESLIDVNGERAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJA3</accession>
    <name>A0A5N6KJA3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">TspO/MBR-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_005247</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TspO/BZRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJA3"/>
    <dbReference type="OrthoDB" id="8841220at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033013">
        <property type="term" value="P:tetrapyrrole metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd15904">
        <property type="entry name" value="TSPO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.100:FF:000001">
        <property type="entry name" value="translocator protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="entry name" value="TspO/MBR protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004307">
        <property type="entry name" value="TspO_MBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057">
        <property type="entry name" value="PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057:SF0">
        <property type="entry name" value="TRANSLOCATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03073">
        <property type="entry name" value="TspO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8303880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="22042" checksum="1EFB1CBF67C135F1" modified="2020-04-22" version="1">MTTFIPSLTLPAAIFANPTASILLPVTLGTAVGFAVSPKKTQKTYMALKQPPFRPPPYVFGPAWTLLYSLMGYSAYRAYSTGLSPLASTEKHLLTKQGATLYTIQLGLNLIWTPLFFALKRPILATIDIVALTGTVSYLTYTWAQVDSVAAWALAPYLGWLGFATYLSAGVGYLNDWNLSDKEVEKSPEGKKTKYVDEKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJA6</accession>
    <name>A0A5N6KJA6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJA6"/>
    <dbReference type="OrthoDB" id="292213at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052241">
        <property type="entry name" value="SLC66/Scramblase_ANY1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14856:SF9">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14856">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="69" mass="8034" checksum="85B7C410B07707E1" modified="2020-04-22" version="1">MASWIAGDIMKMFWFFTATSAIPWAFKLCGMFQMCCDLFLGVQFWMYGDGDKKRDDYRSPLGEKDARLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLE7</accession>
    <name>A0A5N6KLE7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003989</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLE7"/>
    <dbReference type="OrthoDB" id="5819582at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF134">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="34"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="476" mass="54485" checksum="BA7ABBF7054E5450" modified="2020-04-22" version="1">MSLCYSSQPSTIPTSYTESPLTMKPNIFVKGRQTWLDGLRGIAAAIVAWFHFTSGEMEIPFRSFWDEPAEQNRRLIQLAPFRIAFAGQAMVSLFFVVSGYSISLAIIRYRDIDENLVFYRKLTSSVFRRGFRLYLPLLTLYLISHVAFYIGLYDWEFGESEGCPAAKPWSNPFPHLDCLAMSFMTNLNLAGPYSTSGLNMHLWTVQSEFQGSLALYLTILGLASTKPRVRLGVVCFLSLIFLWFGQASFICFFAGLSLAEFDTIRKDLPNVSFNIASGTGRSVMRLIFRKIVTLALFAFGIYLLCLPSDERFPADFSFQTWMKLPFWVDEHIRIICWYAIGAVLVVATLRNHPTLRIPLESRLAQYLGKISFSLYLIHLTIFRTLRDHILDGFCEIFWKKDFDDTRKDDDAFTVIFLAWSCAIIVILPLLIILSHYMTIFVDQRAIAIAHQLEKLAAHDPVDRAVPEQRLGYEVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KNC3</accession>
    <name>A0A5N6KNC3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KNC3"/>
    <dbReference type="OrthoDB" id="3014581at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF90">
        <property type="entry name" value="CENTROMERE DNA-BINDING PROTEIN COMPLEX CBF3 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="36612" checksum="C0313E2478B622A0" modified="2020-04-22" version="1">MLVKKPLNINDEDVIDGMRGTEQPLSQPTTMSFQLLQLRLSEISHNMVDRSPLIMGFSGGLSHDVVMNIDTELQMLLNDTPPFFSMSVPELTANYQLDPSHASKIVHQGYMFYSLLYAQRCTLHIPYFTRGLTESAYASSSQICLQSARLVIQTESQLGTSRISATRYKFLGFLVPVFMASIVLLMDLCYSKKSSNYTKHREELTEAIRILEEAKHESETAKRFLDSLTHVLRKHEVSPASKAAEQLPITPNTAFTGLQPHGDLPLPLSPSSLVGANDIILGDPMYTNGEDVSTYFNELAQTFEQGTEAGSLDWNNMFSGIDSSMVWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KNI2</accession>
    <name>A0A5N6KNI2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">STI1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_004028</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">Part of a larger complex that includes HSP70, HSP90, and immunophilins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KNI2"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042030">
        <property type="term" value="F:ATPase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000004">
        <property type="entry name" value="Putative stress-induced-phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000010">
        <property type="entry name" value="Stress-induced phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000020">
        <property type="entry name" value="Stress-induced phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000002">
        <property type="entry name" value="Stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000027">
        <property type="entry name" value="stress-induced-phosphoprotein 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041243">
        <property type="entry name" value="STI1/HOP_DP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17830">
        <property type="entry name" value="STI1-HOP_DP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="2"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="70"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="8">
        <location>
            <begin position="140"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="297"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="338"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="398"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="8">
        <location>
            <begin position="535"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="208"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00064323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8304659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="613" mass="67828" checksum="DB00009F0688E6DD" modified="2020-04-22" version="1">MADALKAAGNKAIAEKNFDEAVAKFTEAIAIEPENHILYSNRSAAYASKRDFENSLKDAEKCTSIKPDWAKGWGRVGTAKQSLGDLLGAHDAYEEALKLDANYAVATKGLAQVKKSIDAEAKADGVKGDPTAGLGNMFSDPQLITKLAANPKTAAFLSDPTFMAKLQQIKSNPGNTQELFSDPRMIQVLGVLMGVDMSFADSGAFGGAPGAEGAAAPKEAEEDIQMPDVRPSSQEPQSKKAKTEPEPEPEDEEAIAKKKAKLEADEEKRLGTEQYKKKNFDEAIAHYTKAWEIYKDITYLNNLGAAYFEKGEYEEAIKACEKAVEEGREIYADFKMIAKSYARIGTSYEKLDDLPKAIENYNKSLTEHRTPEVVNKLRAAEKNKIDSAKKAYIDPAKAEEARELGNQKFKESDWPGAVEAYSEMIKRAPEDPRGYSNRAASFIKLLEFPSALEDCDKAISKDSKFVRAYIRKAQAYFGMRDYSKSIDACNEASEADVTKANAREIEQQQQKAVSAMYSARENETEEQTKERLSRDPEIQRIMGDPVMQSILQQAQNDPAALQEHMKNPQIRSKIQQLIAAGVIRPTGLIINHYIGLSGWLKSDCLGHGWEIMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KPG7</accession>
    <name>A0A5N6KPG7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Teneurin-like YD-shell domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KPG7"/>
    <dbReference type="OrthoDB" id="442731at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.180.10.10">
        <property type="entry name" value="RHS repeat-associated core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050708">
        <property type="entry name" value="T6SS_VgrG/RHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056823">
        <property type="entry name" value="TEN-like_YD-shell"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32305">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32305:SF15">
        <property type="entry name" value="PROTEIN RHSA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25023">
        <property type="entry name" value="TEN_YD-shell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Teneurin-like YD-shell" evidence="2">
        <location>
            <begin position="26"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8305009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="498" mass="55598" checksum="6D169974A7FF12B0" modified="2020-04-22" version="1">MGYTYSQDDPFQLVLVTNTHPDENPEITLEYDDNGCLIRDEESRILEYDTSGILRAVRDKDRNMLCQYYYDSHGRLLSQRVPGKPNHYLHYRGETLIAATEGDTKTSYISSGDHHWGQIVQKSDQTSTQLWTSDTHQSTLFWLNTSEPSQVHNQAYTPYGFYNSSQSIGRNGQWRDPLTGWYHLGNGYRVYNPVLMRFHSPDAWSPFTSGDINSYAYCCGDPINRIDPSGHFSVFGIQFTWRYLAQAIVGFALSVLAGILTDGASVAIEVGVDLGVAVASDVGTGAVYDVAAGKVPDFKSVGSDIIFGGVGNMVGRGLSLGASKAFKSVSETLEQLLIGAEKLRAAGGKPVMPSQMGTVRSFKRFKLQADQFDEFDSWNKMSAGDKKLFNKGLTEINTKIQEIQSREPWTWIQAKDLPNVGGKNGVASQKFIDFRRMFREERLSLRQAADRAGDMNFTKFKGSKPPQYEIRTSQGDRISFLIDKKSREVTILQVGGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JQF6</accession>
    <name>A0A5N6JQF6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_010586</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000021">
        <property type="protein sequence ID" value="KAB8289673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JQF6"/>
    <dbReference type="OrthoDB" id="3630276at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024957171" description="Cyanovirin-N domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8289673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="19116" checksum="3F78E88DE87DE765" modified="2020-04-22" version="1">MRPILFSLLASSTAIVSAYEISKSDGCMQGNFHDLVIRNSCGDDLSIVKCLAEDVDLRRLDQIEQCFIAGGCDAIDSTVSAVWFSYECNDRQGPVEEVMKEDLRKRATDSSSTSGSTASSSTTTSASTTAATTTSDASSTTATSSSTTASAAASTTATPLSVPQHPTTQQVYAHMELGHQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JQH2</accession>
    <name>A0A5N6JQH2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Serine/threonine-protein kinase SSN3</fullName>
            <ecNumber evidence="6">2.7.11.22</ecNumber>
            <ecNumber evidence="5">2.7.11.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="21">Cyclin-dependent kinase 8</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">Serine/threonine-protein kinase ssn3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">EYC80_008530</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="27 28" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="27 28">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the SRB8-11 complex, a regulatory module of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="6"/>
    <dbReference type="EC" id="2.7.11.23" evidence="5"/>
    <dbReference type="EMBL" id="VIGI01000016">
        <property type="protein sequence ID" value="KAB8290893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JQH2"/>
    <dbReference type="OrthoDB" id="6284126at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07842">
        <property type="entry name" value="STKc_CDK8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000408">
        <property type="entry name" value="Serine/threonine-protein kinase SSN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000426">
        <property type="entry name" value="Serine/threonine-protein kinase ssn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF495">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0010">Activator</keyword>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="17" id="KW-0804">Transcription</keyword>
    <keyword evidence="15" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="26">
        <location>
            <begin position="37"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="380"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="25">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="25">
        <location>
            <begin position="380"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00039418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00040708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00041823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="KAB8290893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="418" mass="46967" checksum="757C6D158FAD639C" modified="2020-04-22" version="1">MYPTRRPPPFYTPSSTGEKTTNPSLGYQSKVRVIDRYKVIGFISSGTYGRVYKAVGRDGRPGEFAIKKFKPDKEGEIQYTGISQSAVREMALCSELSHMNVIRLVEIILEDKCIFMVFEYAEHDLLQIIHHHTQPTRHPIPAPTVKSIMFQLLNGCQYLHANWVLHRDLKPANIMVSSAGEVKIGDLGLARLFNKPLHSLFSGDKVVVTIWYRAPELLLGSKHYTPAIDMWAIGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMQKIVDIMGLPTKEKWPHLVHMPEYSQISTLSASGHAKAGYSSLEKWYYQTINSAPTSAPVSNASLGGEGYKLLSSLLEYDPEKRITAQAALTHPFFTTGDKISSNVFEGVKTEYPHRRVSQDDNDIRTGSLPGTKRSGLPDDSRPAKRLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JQI9</accession>
    <name>A0A5N6JQI9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_008544</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000016">
        <property type="protein sequence ID" value="KAB8290910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JQI9"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF6">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AN1598-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="5 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0843">Virulence</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8290910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="464" mass="52032" checksum="044A0026A105F438" modified="2020-04-22" version="1">MASGGLKMLTSGSPLVNGAILLVIILFTGFVLTRPKKLDLPIVGSFRADQRQALVEGTRKYPDRPFLVPIVPPLVILPISVIDEVRNLPENKTSFIQDIQRSFTAKHTGIGKEAGPELIQALKLDLTKHLASTIDDMQDEIGYGLDKELGSCKDWTSIPMYPKVTRLVGLLSGRVFVGLPLSRNEEWLKSSIEYALLCMGARDAINAYPEFIRTIVAPFLKEVQILKYVRNRGVELVKPLLAAGQENMITWIQNRIKKKDPEKIANNQMSLSFAAVHTTSMAITAAIYDLCAYPEYIEILREEIQQIDGVTKTNLAKLWKLDSFLKESQRLTPSSLVTNVRLVTSPLNLSTGTLPAGSRFGFAAWAIHTPHLPFDGLRYYKLRQIPGNENRHQFVTTSPESMNFGHGNHACPGRFLAANEIKIVLIELLTKWEFRLKGGERPENIMNAMICMPNPRAEVEFRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSK9</accession>
    <name>A0A5N6JSK9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSK9"/>
    <dbReference type="OrthoDB" id="192608at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:001484">
        <property type="entry name" value="HEAT repeat containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040108">
        <property type="entry name" value="Laa1/Sip1/HEATR5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21663:SF0">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21663">
        <property type="entry name" value="HYPOTHETICAL HEAT DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8291869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1016" mass="110143" checksum="2984B8AFA98257B8" modified="2020-04-22" version="1">MSSGRPSSKNGSSELPGRIEPSSTPELDIKKLQSLPSEQQDLYLLNFVSTLTKHVEGLEPDDCTAQQLYLKKELFQILNLVAPPPTRVIRNNLGRCFAHVLGKGDRKLLFETINDLVGIIGSGKTKTEGDFRAKHAAAYCLGDVFAAAGDSAIGLHSLACSALLKLLKPAQNNAGLRAAIFKALSKIVGMVATSVDDTIAKDIWKQTRSYASSEKSALVQIAACRCLKSLCKYTQYYDNSSDFENLKSTIFKTIDSPSALVRHAAAECLAEALVKSHSEEPPRDNDVPIIKKIKRTNTNKRSSVIAGPGLDDDEIPSRPGTPTGNKKSQILILSLQEILKVLSNQYIKTSTTNRARAGIAVCYSRIFKSMSERTVETMYMQIVDHLTVELLSHANITCNRYRLLSTRKFVQIILEDVVGQSILGESGQLDAAKALVNDILKNYPQVIKERAEPSKHTLIATLSALASLIQTLGSAANVIAEGCRDGLLQVLQHPSYTVQIYTSYCLRAFTLACPQQLLPCLTICMNSVNRELNLLTTGRNSPRRCVGYANGLSAMISTANLQPLYGSVDVNSRVLSLATSLLKSSLVANQNYASQALKFSRLLTADVSKRIAAMLTNTSAFLRSLPSKKLSDDVTQRLTPSLQLQDLDLMVQRRVLQCYARLVTLSPIGGSEALLQSNLLTLAVSFFADPENYSPSSLSSSIASSAGNFETVWDVGDNSGFGVTGLVRGFEVQKLASEQENGSQDDWVKETGSDIDISNVLLSPICSSLEHDSISLYLGDIERGNSLPDPPATEVINIAIKLFAIAFPITPPKIQESILEQIATFLSKGALQRDPGRKAAINVNIATALFSTLKVAVKETSSPPGDLTSPAVEKLMQEIIRSFVVHQDQYVRHIGYESLARLCNSSGNTYTNQEIKHLIDTIVSNREPSARAGCAMALGCIHSQVGGMAAGFHLKTILGILMSLCNDPHPTVHIWALESLSRVADSAGLTFSGYVASTLGMLCQLIVNNSSHCALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSL3</accession>
    <name>A0A5N6JSL3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_006652</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSL3"/>
    <dbReference type="OrthoDB" id="448450at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000048">
        <property type="entry name" value="3,2-trans-enoyl-CoA isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8291872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="271" mass="29836" checksum="2598F151F22E95BA" modified="2020-04-22" version="1">MPQSEPVTLEYKGRIAVITIDNEKKLNALTQDGYYLIAKFMREVATHDEVFVTVLTGKGRYFSAGADVSISREQPTGTDLARHWLTSFVANNLNITNAFYTHPKILITALNGPAVGLSAALIAFSDFIYCTPQTFLLTPFSSLGLVAEGGASRAFVQRLGISKANEALIMSKRITAEELLQVGFVNKIFDIQKGDEDKFKSLVFEEIDARLGTHLIGDSLLKIKALIRKPERDLLDAQGVAEVFGGLERFAAGIPQEEFRKIASGEKKHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSL5</accession>
    <name>A0A5N6JSL5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ClpP/crotonase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_006652</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSL5"/>
    <dbReference type="OrthoDB" id="448450at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000048">
        <property type="entry name" value="3,2-trans-enoyl-CoA isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8291873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="26751" checksum="A7005A1F5265CB5F" modified="2020-04-22" version="1">MMRFSSQGADVSISREQPTGTDLARHWLTSFVANNLNITNAFYTHPKILITALNGPAVGLSAALIAFSDFIYCTPQTFLLTPFSSLGLVAEGGASRAFVQRLGISKANEALIMSKRITAEELLQVGFVNKIFDIQKGDEDKFKSLVFEEIDARLGTHLIGDSLLKIKALIRKPERDLLDAQGVAEVFGGLERFAAGIPQEEFRKIASGEKKHKLHCIKLQTTLELESADIPMKSIEAIYILIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSM1</accession>
    <name>A0A5N6JSM1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSM1"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08276">
        <property type="entry name" value="MDR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052711">
        <property type="entry name" value="Zinc_ADH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF1">
        <property type="entry name" value="OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="15"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8291878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="209" mass="22097" checksum="2A2180A40B91477A" modified="2020-04-22" version="1">MSISTINKQWTTQQSGLQDLTLGSSPIPTPGDGQVLVKINTVALNYRDTEVIMGLYNHHKSTDSESSSLVPCSDISGTVITSNSSRWKIGDRVLAIFNQTHIRGQVTSKDMASGLGLPTEGCLQEYRVFDGEGLVKKPDYLTDEEACTLPIAGVTAWMAVNGMRPLGQPGGKGESVLIQGTGGVSISGLQIAKASGMEGNSDTTVSFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSR9</accession>
    <name>A0A5N6JSR9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_007866</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSR9"/>
    <dbReference type="OrthoDB" id="10264446at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051754">
        <property type="term" value="P:meiotic sister chromatid cohesion, centromeric"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901991">
        <property type="term" value="P:negative regulation of mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098813">
        <property type="term" value="P:nuclear chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000016">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002554">
        <property type="entry name" value="PP2A_B56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01603">
        <property type="entry name" value="B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028043">
        <property type="entry name" value="PP2A_B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="683"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="684"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00064351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR028043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8292122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="706" mass="79181" checksum="0D17A5BB195AF95B" modified="2020-04-22" version="1">MKGFRQRVLSRTKDPNKSKSKKGESKDGTSSPSQSNSREAGQSPAVTPSSSSTTLNDLRNKPLPPNDGTSSSAGPTAQPPLNPALNTMSASDRFNTGGGSPSPATPNRHGALPPSVVISPSAPHIPPPGSAETMPHDLAPPKAGQKSLMFDRLQTTPKDVPEGIRTPKRQHSSRFDISPLRELEKLPGFHEVPPNRRQDLFMQKIDQCNVIFDFNDASADMKSKEIKRLALHELLDYVANNRQVITEAMYPKVVEMFSKNLFRPIPPPMNPQGEAFDPEEDEPVLEVAWPHIQVVYEFFLRFIESQDFNTNIAKAFIDHSFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLNLRSYIRRSINNVFFQFVYETERFNGIAELLEILGSIINGFALPLKEEHKLFLTRVLIPLHKVKSLSMYHPQLAYCIVQFLEKDAALTEEVVLGLLRYWPKVNSTKEVMFLNEVEDIFEVMDPAEFAKVQEPLFHQLAKSVASPHFQVAERALYFWNNEYFCNLVSDNVEIILPIMFAPLYENSKGHWNRTIHGMVYNAMKLFMEINPQLFDDCSHDYTEHQNNAEAREKARENKWKALVEQAGRSKANGSILPTGPASPSRIKVTPLSADDIDPIAEDNQKRLDSIFQKPAMIVNGLVSDLDVDVDAQRSVSGSSTQAVLGIVSSSAVASKDLDGDPETGDHSFIDDQASLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUQ1</accession>
    <name>A0A5N6JUQ1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUQ1"/>
    <dbReference type="OrthoDB" id="5314201at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8291691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="240" mass="27852" checksum="404ECD875BD6742A" modified="2020-04-22" version="1">MSAEQQYLEPALREIAAKGDSGQDRAYQALKYMQECLNFLVNRTEIYTEHMEEYQCHQMACKFAIDTGKKELQNQAAPQASISATRQRQNSQTQVQYRNNRRRSSMFEEMDAEQQLLRSMGISLPTENDTDDARTEFLESILHERDEKLRGHTANLESTTETIISSHVHNADVTMKLLYNALQADSMYGEVQLLDPDIVSSFSTFEEEIKNLQENLEAVNLQRLQLKNVHKEQLIKRWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUQ9</accession>
    <name>A0A5N6JUQ9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUQ9"/>
    <dbReference type="OrthoDB" id="9981546at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="5"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8292565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="366" mass="41572" checksum="9C194D0394C413AE" modified="2020-04-22" version="1">MVDSFTGIASLPNELLINSLSLLSTRELLPIASTCKRFHNSIIRIIHHRLLAASSLKDFKLVLECYHPSTRLDTPHLFCDYIGTDGLSDDFGREEDLYKEVEDTGRLGKMFSLYSHFRPVQPEKRMVWKKSPAGGARPDLLSKSQEELVSQDIDLESYEYFSQLCTNTRLAKVEQKGGSFKSCGNLGEGVLRVFRGWLSDRAEANERHVDTPEERENRLLWAGAEKNVGLRLKVLKQEEAPEPIMLGRDEEPPVFYKLQYEELVIRTTQLLLSIEDSLTREVQNSGMTCSRDGVNQTSALSSKIKAMETNYSKMWTHGLELFVNSAQKALWLQARSKGRKASSSNLIDYSWNSPSRETHLSLFVCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUV8</accession>
    <name>A0A5N6JUV8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_008138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUV8"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8292407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="198" mass="23017" checksum="8D493E09991E78EC" modified="2020-04-22" version="1">MGPLTLAASHNLVSDSVFGYQTNPPTQQVETIGSWQLEGLNKHSWTLSKDLRKLIQKTFLSFPFLFVILTHSFQLYQVPDQTSLLHQLVISCGVIDKLQPFKVNEYKVNEYNDKLLTIHLEHLQIAVPLQSFLETAKLLQDYQYLNNRIYLLYFKVLSSSDHRSLSYHTNPRKNASDPRNRSHLHCCSHRPHRSRCID</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JV08</accession>
    <name>A0A5N6JV08_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JV08"/>
    <dbReference type="OrthoDB" id="4769at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8292487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="72" mass="7965" checksum="FDC3B51463E5E432" modified="2020-04-22" version="1">MRILSTPQVLHPHIPIYSPNPSQPNAHPHNANPKTHITATAPITPHPQTQNHKLNRSKLISPPLLLLLTTPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JV22</accession>
    <name>A0A5N6JV22_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JV22"/>
    <dbReference type="OrthoDB" id="3648173at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8292356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="31899" checksum="D89D8064B027AAD6" modified="2020-04-22" version="1">MLLNTPTYLGINLNADEGPLLKAVSYVFISLTVLTIAVRSFSRWYTKISFGLDDLFILVAAILSIAYAYEQTITTGPVLEDLCCHWRSNPHPSSRWGQWGLGCCCFNEIDAGLWAIIELNLWILVASIPTFRPLLGKISRDYSAKRSGINGSGSGGSSEYPLSKIRTRTTGTLFQKHQRNLDLDPESVFGFGDLRGEMRSQGSEGSGMNIGMPRTGERAGTAVSGDSGYDDGLIITAVDAEGSRNAYGYACPRSKGGNCSMEKERWSVEMRDLAGIRVQKDGARNFKRNAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWS5</accession>
    <name>A0A5N6JWS5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWS5"/>
    <dbReference type="OrthoDB" id="4436466at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024871043" evidence="1">
        <location>
            <begin position="24"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="225" mass="24912" checksum="84335203AC842646" modified="2020-04-22" version="1">MGLIRTTFTTALLGATGAASGWAVWTRNSKFIPISPTDPIFSSPAYARQNPNRNPATQDLCQRKVPLNKIKPQLLEKDGKLVEAFAAGVWSGYGFAYQRSYLSKKYQNTTTTAHQLWTAPQFQSSTYEVGTQVTDHFEVVSKSPTSIVFRCGDSPLNTGVRDSDGLFEMKASIDKAEGVAVFELKSVFFKGTGKSTQKPMPEHIEFAHRLYTKLWMETAVGNCIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWT1</accession>
    <name>A0A5N6JWT1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWT1"/>
    <dbReference type="OrthoDB" id="17458at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="76" mass="8332" checksum="1542F9A87B42294D" modified="2020-04-22" version="1">MMKDGGVTGWMSIISVVFPCFFVGTGGWDLFLGMGMQTNANANAHNKAWIYDCVIGASGQVRSDPSSYDDRWIRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWT4</accession>
    <name>A0A5N6JWT4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_007729</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWT4"/>
    <dbReference type="OrthoDB" id="17458at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="98"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8293413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="296" mass="31427" checksum="9320312B5F4F4B3D" modified="2020-04-22" version="1">MSSQDKYNIDVVSRYGQPVPVIILAFCFHSSMLKRSGILLSSCRNLQCYYASSDAATTSVIRSSPAFPSASPHPQRRTYAIVSDGRSANQHPDLQWPELTSACAVPTPYQIFNQQKGSPYSKHRFYELVKLYHPDKHGVDTNDGLDFDTKLSRYRLIIAANDILSNPVKRSAYDTYGAGWNGRPDVLEPRDSRGESRGWAGPRGAQPERHVGGLGAVVQARCGGGAGAGVCVERGVRLADCGVCGGGGRGTAGARGPLLGAVFGADGYVACEDEPGLEGAEEGGARSGWESGGADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWU1</accession>
    <name>A0A5N6JWU1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWU1"/>
    <dbReference type="OrthoDB" id="17458at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8293414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="120" mass="13534" checksum="87FF8825EA30E049" modified="2020-04-22" version="1">MSSQDKNRGYRSSNLQTTLEYRRRLSIWSTCASHHTGFLLSFQYAEEILSRISFCVAAPPTSNIRHSIRRAQRKPTPRSTMARTHLRMRGPHALPNLQSAKGLPVLQTPLLRIGQAVPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWU8</accession>
    <name>A0A5N6JWU8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_007664</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWU8"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000637">
        <property type="entry name" value="HMGI/Y_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF38">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00354">
        <property type="entry name" value="HMGI_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="290"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="184"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="242"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8293340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="751" mass="85921" checksum="55301B66E8EA5BB3" modified="2020-04-22" version="1">MYQSNKPFPQLSCSVIPVKIERNGISRFTFNRSVPLNRIFTLTPKLDHFHTSANTQWTFSKLPYHNHQQLPSYHTIHTHIHTSIHLLKKEAIFEWSDHSTSPDRDDVEEIIRQTQGGYRFTPRQPRVVRAPTRRRVQIDESCDHSSVNFQNYKFERFDMRAGSMDGSDGSNSSAITVITSATSSCGGDPWSAGGFVEEEEEGHEHNGSAGGSWDGEHTHEHSQDQDVDMLLEPKLEPLEEELNLESVAPRTPTTLLSPTQAKRPRGRPRKHPIQTTEPLNKVTKGRSKTGCITCRRRKKKCDEAKPRCQNCEKNAVVCEGYPEKQVWKSGKEKAEEARMRRVSIPSITLQPVIHGVETSGDKVFFEHYIYRLSHIFTVEGAENNAFKDQLLPMAVRHVGLMHSILALSSKHIDYDSDYGQRLLQQHPDVDRETLEERSQYHHAEAMKELHHDLDRQEKGDIDNTVVSARFGQMLCLVLQTLADPNPNGAHRIHLTAYQHLIQQSPPEEGPFLNFIQEFFQFHIILDEIISLPEGRARLGTVSDDWDIPSNIIQPDAVRLLGVNDGLFLFMSKITNIRNSIRNNMQKKIDPLVDYKALYRAAEIDAGIRDWKPAWPAGDSRDLAGLLYKQMMWVYLWRTIYPPKNTCWKPDPRITKAVDDGIALLAQVPPRDPAQTLVLAPAFIIGCAAFEKRQREPIRKAIGVVKAYMEYRNSDAALRVLEEVWKLMDNQDERSWDWQSLAHNMGMDFLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZ97</accession>
    <name>A0A5N6JZ97_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8294702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZ97"/>
    <dbReference type="OrthoDB" id="3559122at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8294702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="177" mass="19129" checksum="767C8FAAF2303B84" modified="2020-04-22" version="1">MCGEELDGLEGDVLGGLTEMVLIMEEEVEGMIELSDVLKEYVEELELADLDGWVANLTPSKSNCGTDIGERPLESLGMGLKNWKGNLGTLGIVDGKESIRIGLDDGVKGRISLGGLLEEVEEDVLGWRVRGTSINSDNYGSDERSEVIIEAGGPTPITNYRKEKSHQAGCHFSTSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0D3</accession>
    <name>A0A5N6K0D3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0D3"/>
    <dbReference type="OrthoDB" id="5419821at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39639">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39639:SF1">
        <property type="entry name" value="DUF262 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="370" mass="42191" checksum="0C772EB7E6F8937C" modified="2020-04-22" version="1">MNGEIGFLDNSHPPKKWYYCHPTVDGVVTPTSSRNICPDGLKKFFDQKVFCCYEYDHLIQETEETMFQLVQRGIALSPAEKMRAMSTEWARFTRLYEDDYAMVINLSKQSRASGFRLILTIFTMIQEVLSGPTSGRRKKAVPSLQASPQALMRVLEDPEPISMGLKLAFKDVFDRFESLIKKSSTRLSTGRYKIIKDSVFDPAPEFLKDADVNHVRTFSPLELVASGILISYHKDKRSDDALLEDIKSMRRFLRLKHKDLRVNAQCWTTAWEFISEHVNRNSSRNNFALRLQTHRQKADNSVPIGLGMSRRVRSGSESSMLSELDSLFESDLELDDDSSDGPLSNRSEPISLKRAMGTSVDTQASKKLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0E2</accession>
    <name>A0A5N6K0E2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0E2"/>
    <dbReference type="OrthoDB" id="4986826at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="4"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="156" mass="17761" checksum="778A39F218329FB3" modified="2020-04-22" version="1">MDSMAPELLKHILRYLPISSLRLCRCVNRTFSILAFSYLFSNIPQWLDPEKSLQLLVSLAHDAFNRPAVIWSPWATVPDIHVEVAWLQIVWKTFKGGVFTDGGSPEGLTAENFARLSGLVEMSEERLGTAQTRYLLFKSYLKRPVLQVGRRKLPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0E8</accession>
    <name>A0A5N6K0E8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0E8"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8295266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="71" mass="8014" checksum="5EDD4F63281BB322" modified="2020-04-22" version="1">MVGQEIDGMKQKKKHYAALEGLRSEDLYIETETAEMQVQIKEEIAANAGRSINDYLTQNLFVNTVLLVTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0J2</accession>
    <name>A0A5N6K0J2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Probable beta-glucosidase E</fullName>
            <ecNumber evidence="5">3.2.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Beta-D-glucoside glucohydrolase E</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Cellobiase E</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">Gentiobiase E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">EYC80_007154</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="5"/>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0J2"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000003">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:002666">
        <property type="entry name" value="Probable beta-glucosidase E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF20">
        <property type="entry name" value="BETA-GLUCOSIDASE E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fibronectin type III-like" evidence="21">
        <location>
            <begin position="737"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00024983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00039576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00041599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00041811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAB8295239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="822" mass="89444" checksum="C880282F7134CDE5" modified="2020-04-22" version="1">MTLAEKVNITTGTGFRMGLAVGNTAPALNVGFPSLALQDGPLGLRFADNATAFPAGITVGATFNKDLMYKRGKAHGQEARLKGINVILGPCVGPLGRMPAGGRNWEGFGTDPYLQGIAAAQTIKGIQEEGVIATIKHFIGNEQEHFRQSYEWGLPNAMSSNIDDRSLHELYGWPFGDSVKAGVASVMCSYQMVNNSYSCGNSKLLNGILKDELGFQGFVQSDWLAQRSGVASALAGLDMTMPGDGLIWANGKSLWGPELSKSVLNGSLPVSRLNDMVTRIVASWYQLGQDDKSKFDGKGPNFSSWTNEEKGYVHAGSRDDKDKKVVNKFIDVQGTGDKAHSIIARQVATEGTVLLKNEDNLLPLNKDGWTSKEKQEVVYRIGIFGEDAGEGDGPNACPDRGCNKGTLGSGWGSGAVDFPYLISPISALKKSFSKKHVYITDFPTNSPPFKKAPAIIKDQDICIVFVNSDAGEGYIAYEGIRGDRNDLNLQHRGEELVKQVAKDCGGGNGSTIVVIHAVGPVVMDEWIDLPGVKAVLMANLPGQESGNAIADILVGEVNPSGKLPYTIGKSLPDYGPGGQVLYYPNGFVPQQNFTEGLYIDYRHFDKYNLEPTFEFGFGLSYTTFEYTNMKVNAILPKSSFPAARPNGIPPPTFDDKIPDPSEALLPSNFRKLSKFIYPYIDKVSDIKQGKYPYPEGYHTKQIPSPAGGDEGGNPDLWTVHATVSVDIKNTGNITGKEVAQLYLEYDKLSGEAAKVDFPVRVLRGFEKVELAKNETKTVKFDLTRRDLSYWDVVRQNWVMPTEGTFTIRVGASSRDLRVTGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0J7</accession>
    <name>A0A5N6K0J7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_007198</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0J7"/>
    <dbReference type="OrthoDB" id="416470at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047867">
        <property type="entry name" value="Ribosomal_uL22_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501:SF10">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8295291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="153" mass="17510" checksum="8D7F0330A0DBD9C5" modified="2020-04-22" version="1">MGLGKLERKSTENFKARYIVTKDGKRVKVEDPTTLYVDEAWCGKGDWTKSYDFRARGNVNIMKNRTTSISVVLKEEKTRIRLHEEREEKLKNKKVWVQLPNRPVTAQRQSHGNSNGQGEAFCDSSRNCRGSTFKLQINSAEKLSQSIICSLCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2F5</accession>
    <name>A0A5N6K2F5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">40S ribosomal protein S29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_008996</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2F5"/>
    <dbReference type="OrthoDB" id="10252683at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.830.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="entry name" value="30s Ribosomal Protein S14, Chain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01364_A">
        <property type="entry name" value="Ribosomal_uS14_2_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023676">
        <property type="entry name" value="Ribosomal_uS14_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039744">
        <property type="entry name" value="RIbosomal_uS14_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_uS14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004424">
        <property type="entry name" value="PRK05766.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010:SF2">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8296214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="107" mass="12539" checksum="9EE4AE78D9BB3220" modified="2020-04-22" version="1">MSHESVWMSRPRTYGKGARGCRVCTHKAGLIRKYGLNICRQCFREKASDIGFVKFWAFARKGIRTRTSMVILRRAFSDEGRTLMDTCVLRHTLRWDVLEVLTPFQMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2F6</accession>
    <name>A0A5N6K2F6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2F6"/>
    <dbReference type="OrthoDB" id="10610740at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8296347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="182" mass="21082" checksum="26F0490CFB9B9592" modified="2020-04-22" version="1">MCTNPEYQLNDFDIQTPIRLTITKKNFVTIHPQKPKLLKFAAVPNRCITESVIRVFIPRNSTILLLHLDQLQTLHIPNYCEKLSVDFAVNHPSPYSCSPSFPKSYNCPSDFDNAKKKRYRGRKLEDVVCECSKVKKEVFAGYRRKVPVLQNADEKQCNRTSHRNKNVEMKNYFAQNLICATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2G2</accession>
    <name>A0A5N6K2G2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar protein-sorting-associated protein 46</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2G2"/>
    <dbReference type="OrthoDB" id="10266568at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="21899" checksum="F022883081387FDB" modified="2020-04-22" version="1">MSGLEKALFNLKFTAKQINRQANKAGQAEKTEKDKLKKAIMQGHPDIAKINAENAIRKQNEKLNLLRLASRIDAVASRVQTAVTMRQVTGSMTNVVRGMDQAMKAMDLEKISAVMDRFETQFEDLDVATGYYENATTSATAVATPQEDVDRLMNQVADEAGIELKQEMKSPEEAAPVKSNPTEVEEDGLGERLRALRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2G6</accession>
    <name>A0A5N6K2G6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SRP9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_009119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2G6"/>
    <dbReference type="OrthoDB" id="5419752at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039914">
        <property type="entry name" value="SRP9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039432">
        <property type="entry name" value="SRP9_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12834">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12834:SF12">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05486">
        <property type="entry name" value="SRP9-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP9" evidence="2">
        <location>
            <begin position="5"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="310" mass="35253" checksum="4DF472C144562F43" modified="2020-04-22" version="1">MPHLPTAQEWLTQSSLLLKAHPSTTRITTKYTILLHARDSPHAPSTTHSTATKPRLPKPKPQSDTAAPTPEPPRATLTITTFHPQSGVNLKYTTNKAAEKRKRNERNLISKIELTNTIPKRTTHSIPTNLPSQHIQKLQNTSHRFPLLTLTIPHHSVGFDGHSKNVDLDLVIQVTCLLFYSGENIYSEEEAGRDVRYIHDGWMDIKKSQFYPSRHCLDHIKSASQYSNQTSRQTNISIIFILSIRSSDHGMPPNHDIPFNHPCPNDCYDSYSSIPPNQIFPTPQLLHAKILFVHKPHTHRHLCMQAPRMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2H0</accession>
    <name>A0A5N6K2H0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">VLRF1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_009081</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The VLRF1 domain mediates binding to the 60S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ANKZF1/VMS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2H0"/>
    <dbReference type="OrthoDB" id="429841at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047139">
        <property type="entry name" value="ANKZ1/VMS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041175">
        <property type="entry name" value="VLRF1/Vms1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036">
        <property type="entry name" value="ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036:SF2">
        <property type="entry name" value="TRNA ENDONUCLEASE ANKZF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18826">
        <property type="entry name" value="bVLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52044">
        <property type="entry name" value="VLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VLRF1" evidence="12">
        <location>
            <begin position="64"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="281"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="305"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8296312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="470" mass="53453" checksum="09B143B97277A831" modified="2020-04-22" version="1">MIWFSTPTMPKNTYLGIYRAIFTNEEQEKEASINEIVQKKQLSPKPQTKIPVNSEGIPLPEAYKGPHIFMCMIGGGHFAAMVVSLAPRQVKNPQATTGPLTKEAVVLAHKTFHRYTTRRKQGGSQSANDSAKGAAHSAGSSLRRYNEQALTDEVRQLLTSWKGMIDTSELLFIRATGTTNRRTLFGPYDDQVLRQNDPRIRGFPFSTRRATQNELMRSFVELTRVKVLEVDQEALAAKRLILKAHADPTLPNPEGKTPFDLCGDRTSRDAFRVCRHELPSPSTGYSWETSHVPAPLPRSEAQQRAAREHDEEQKRKAEQKKVDDERMAREEAEQKLRGDANRHFYMNIKTRHTNPSHDTLSYITYTYTYTHIKYAPYTGPPPSKRGIIVKRLSQPSSIPTRICVLTEKEISDSSDWDWDSEYQIGICHCHFVTFFLSSADSRRAIYILRSPPISSILTHSSMNFEIRSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2H5</accession>
    <name>A0A5N6K2H5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster assembly factor IBA57 homolog, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_009123</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GcvT family. CAF17/IBA57 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2H5"/>
    <dbReference type="OrthoDB" id="191995at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057460">
        <property type="entry name" value="CAF17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GCV_T_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045179">
        <property type="entry name" value="YgfZ/GcvT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602:SF0">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25455">
        <property type="entry name" value="Beta-barrel_CAF17_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="CAF17 C-terminal" evidence="6">
        <location>
            <begin position="129"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00093447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00093637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8296363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="242" mass="26390" checksum="40B3B48B35E26C13" modified="2020-04-22" version="1">MRAKFDVEIVREEDRGVYSLWGAVGDVKWETSDHGIVCVDSRAPGMGKRIISNGAGIQTEDNDVQVQGDDVYRVRRYLIGVPEGQNEILRESALPQESNVDVMGGIDYGKGCYVGQELTIRTHHMGVVRKRIVPMMLVPDGEDMPGLGELRFHGGDLASGLVGGESIKKVGGKRPAGKWLSGVGNLGLGLARLDEMGRWMTETGEGNHGDSSEEFVVEGKGEKEGEVKKIRVRAFPPAWIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2I4</accession>
    <name>A0A5N6K2I4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2I4"/>
    <dbReference type="OrthoDB" id="5599902at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949:SF0">
        <property type="entry name" value="RE27538P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949">
        <property type="entry name" value="WHITE COLLAR 2 PROTEIN WC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="251" mass="28179" checksum="8682C55579EA87AE" modified="2020-04-22" version="1">MDEHTHHHHQAPSGSASSGDDVRQSQVFQGYYPSSSTVGGASMVPGAHDGRPLPRPGHPIAAQSKSDDDDSVDVFGNVPEAKKLTLDTVDINEIPDSFRKSNSVYQRSWFPLQMQSPPPSAHGSRFFEEEDTDDEVDGGRGRSRRGRKMFSVQLPDGNEGEIPIPRMRKSQRALEVKLNDLGYRMTWHQSRVFADKSVFLQKALDAWRNKVKETIGAAGRDVTATPHFDTRSGKRRWLESNKKREQQETEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2I7</accession>
    <name>A0A5N6K2I7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2I7"/>
    <dbReference type="OrthoDB" id="5599902at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="129" mass="13816" checksum="21DC64F2A5D8A413" modified="2020-04-22" version="1">MDEHTHHHHQAPSGSASSGDDVRQSQVFQGYYPSSSTVGGASMVPGAHDGRPLPRPGHPIAAQSKSDDDDSVDVFGNVPEAKKRKFILVEDPIKQSRVLIPKEQLSLSTFLVPTANAIPSPIGTRQSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2N7</accession>
    <name>A0A5N6K2N7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_009132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2N7"/>
    <dbReference type="OrthoDB" id="10584948at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024925613" evidence="2">
        <location>
            <begin position="16"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="134" mass="15450" checksum="38505D8FE88AF3BF" modified="2020-04-22" version="1">MIITVILDLTTGVIAILASAEEEKLEIHFEHSTREVDIKNRNSTLELLPSLDPKKVVLSHLYPLQLYKSKRLDLRIFPKFKIPQSTTTYPLTISSGSHPPRRLDEHKLYLIKSQNPFDHPNHPTDLFVRQSQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4J8</accession>
    <name>A0A5N6K4J8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_002643</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4J8"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF7">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="125"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="399"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="868"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="399"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="420"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="873"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="891"/>
            <end position="901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8297286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="992" mass="111179" checksum="1C73715393A3557E" modified="2020-04-22" version="1">MDTYNQLRRAEDGDGDVNIDVDDRSGGVGDRVSREQGEEQCHSYAEINDERRDFHYKGMAKAGRFKCMICGQTFGRVEHLTRHERSHSREGWLRVMGGDLCDALRRHELVHKRTKRSSLGRGARACSACAIARRKCSGGNPCEGCVKRSIECVAHSNTTTTITRRKESVGVSNGSSYEMVGIVSNQAGERSTSPQSQSLWSKMISPIDTQPQINPRSSIGQYHQGFEMENIDVTGQQMNVQNLVPGVHQQFDQFTSPKNQTSDQISEDARRDSVISYDHQSTSSSILPLHSMTNLDAATNSLMNSNGQTSSQLHIPNTSLSDGLQASAGSWTQYNLSSINWLPYDWVPDYQLEDDTSAMRIIDGTTDINGPSPIYIPGDSISRDAPYSINNATVFTPVSQRQDQIQIDNSPRPTLPSEGAPTTPNSHTTRSTGRYYVDGHGSRLPHVRKTPSEVANSCPLISHPTIDDLEAMAAVGSHYHQNGNYAKPMHEFLRRAIISTGIKGDSGCRNVVMIQVKLLNCVGMMYCGCDELSQAAKSYHRDLIDFCCYEWKASNNISRIGTTDSNLSETYQAKIEWKEWHDAESIRRTGYCIWLLDCMWYFHFQIRPSLSLDDSSVLLPSQEVLWEAESAIDWKQLLSCSSTSPTLHHALQIMYTEKRLQSSMGEFSRILLIHGLFRRTWEVESYLKQPLTQWTPTAQKQTLQHLSISSSIWLPGLQTYTNWRNSACDCLDILHWHANSVIGAASGMEHPTVMHLHLARVVVLTPFAKIDKFAQYLSARSNPTTASSHPREIEGDAEKEIVEMSTCIKRWAVEDQHKARLAVIHAGALFWHVRRFSVDAFYEAPAVYLATLVLWAYGLFAIHGTSRTDVDGNGSQRNNTSRGKNEARDDAYDEDDDEGELTSDFYPSSMQLDRPADDELVQLFVKRGQRMKALVMGVGNLCQRDGRGAGRVLGEGRKLLKAGKDTWGFAWVLEDRLRRLQEASAAWREGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4K1</accession>
    <name>A0A5N6K4K1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_002449</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4K1"/>
    <dbReference type="OrthoDB" id="1924260at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="525"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8297054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="605" mass="67841" checksum="30E6A7EAD1C8C018" modified="2020-04-22" version="1">MAGPGGGPPRRSHTKSRKGCETCKRRHIRCDENFPQCRNCTKHNCRCPYMDMPVQEERAATPEKADLLWTPEIEADIERWQQTGNFPFPDLYIYPAPNPQYFTFEDLRLIHHVASVSSELSMHDAGNFTIWTRQIPLLLKIGSNYPFVMHALLALSATHLAWLTDCPLTANMAYIHRGIALKGLHEAIGEFSRQNSDAVLGASLLLSWQATEWRGWTQLMHGTSSVIDAMQPWKMESQFGDFIAEQSTFPTAPPSPAPGHTKLSQPRKQDLDALQRAYAQLQKVEIHLKSNGEDTKAIQQLMSFVRGVRKVSPSHTAAQRFEMLNPLRAWLFWLPVMFLQQTRGSPSALVILAHYYTIALVVEPLFPEVGAAYFGSLSLGPIEEIARRLFSINVSQTSDSNMQTPLHLMEYPIDMVSKFRSRMGWVQPERTASFPTFSHTSYGMEDNFNTISPYGNPAFTYSQEHLMTMPPDPISTTAIPPLTLDPYANHYLGIPSPSGFGGYHSPASSNFGEGSTVYSEHGDDFALYEGQGSGSNFGGTTTPSFQFEPRSSADPIKFESQTSDHMQQHMHHLPQFHSYTSNPQPLPRSPYDTTPADFKGKGPEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4K3</accession>
    <name>A0A5N6K4K3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_002627</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4K3"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF27">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="376"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="400"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="412"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="432"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8297261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="618" mass="68034" checksum="0278061B58A93362" modified="2020-04-22" version="1">MAQALQLHKDLDHDPEKRDPDDSGNFTKLSFIDREIRRRTMWACFLMDRFESSGTGRPTIIKEEDLQIQLPIKEHMFLFDIPGQTENLHGEIAHPISPGRPMANPKQNMGVAAYVIRSIAIYSNVITYFSQGGNEKDPYPMWHPESKYPSLIKELEDFQKAMPDNMVYNIENLRTHKTEGLANQLIFLYVVIQQTILTLNRFAVPLEPGGPLSKAPKEFVTKLGAKAMEAAESITQLIADGESYSITAPFIGFCAFSASTILTLGAFSKNPKLEASSKKNLTITVTYLAKMKKYWGMFHWMSEKLKTQFRICADNAVAGSNGTLNSVSLHYGDWFEQFPHGVSKSDYEDPAAPIKKEKGDDAVLEHRSNLATVEKYVQGLPSPGQRPNPKLAKAKTKRAQSSSQPSRPQQLGRVQTMPNIQTPHPGIPLSTPPSSHQQVPAQQAPQSSYSQNILSPTTLCPPPQFPTHQQLLMPSQRPHNMVPQQLDGPLAFNDYTAMDHSAINGSGIYGNGMHGTVMNPNITPGPNHNGDGTGINWEDIGGMGNVFDGMGLQGGNAWFPPFNTGPPDLDMGGGLNGDDVFGGAAFERDFEMRNGEHGVIRMDTNIDRANGHGGMGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4K6</accession>
    <name>A0A5N6K4K6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4K6"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049174">
        <property type="entry name" value="Beta-AFase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049049">
        <property type="entry name" value="Beta-AFase-like_GH127_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049046">
        <property type="entry name" value="Beta-AFase-like_GH127_middle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43465">
        <property type="entry name" value="DUF1680 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G08910)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43465:SF2">
        <property type="entry name" value="DUF1680 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G08910)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20737">
        <property type="entry name" value="Glyco_hydro127C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20736">
        <property type="entry name" value="Glyco_hydro127M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 middle" evidence="1">
        <location>
            <begin position="59"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 C-terminal" evidence="2">
        <location>
            <begin position="161"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8297308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="277" mass="31697" checksum="96F2F322EC1CDC44" modified="2020-04-22" version="1">MEDNSHMSTSSHQVIQIYLSGQKWFTCACCPPNVTRLLGYIGGYLWTSSKDERKNAAEINVHMYTSAVLKIQLGEHTVELEQKTDWPWDGKIQFDLKTPHEISATIRIRIPGWASNWTILPELEGYSSELSKGYLTIPPEYLKTHSNFQLHIPLEPRYISPHPYTNQNIVALARGPIVYCAEDHDNPWVNDHFKSLVFSTRGEITEKDADVNNEPYKQLTALGAATRFRLPEQARPDLGHNVDGFSEVDIEELHFIPYALRDNRGGKGHMRVGLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4K7</accession>
    <name>A0A5N6K4K7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Clp R domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_002600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4K7"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070370">
        <property type="term" value="P:cellular heat acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000120">
        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000010">
        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="71"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="483"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="9">
        <location>
            <begin position="654"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="744"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="756"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="767"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="783"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8297229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="792" mass="87981" checksum="7FF048ABE2370400" modified="2020-04-22" version="1">MPNIKLLQDAVSQIRGTKRVDSKTADAEEDNENLKKFTVDMTAMAREGKIDPVIGREEEIRRVVRILSRRTKNNPVLIGEPGVGKTTVVEGLAQRIVNADVPDNLAACKLLSLDVGSIIAGSKYRGEFEERMKGVLKEIEESKEMIVLFVDEMHLLMGAGASGEGGMDAANMLKPMLARGQLHCIGATTLNEYRKYIEKDAAFERRFQQVLVKEPSIPDTISILRGLKEKYEVHHGVTIADGALVSAATLAARYLTQRRLPDSAVDLIDEAAAAVRVARESQPEIIDSLDRKHRQLEIEIHALSREKDDASKTRLAQARQDASDVEEELRPLREKYESERKRGKDIQEAKVKLDQLKVKMEEATRLGDTSKAADLQYYAIPEQQTFIKTLEREKKAADAALSSSSNPDSGGSLITDTVGPDQINEIVARWTGIPVTRLKATEKDKLLNMEKALGKVVVGQSEAVKAVSDAIRLQRAGLSNPNSPPSFLFCGPSGTGKTLLTKALADFLFDDEKAMIRLDMSEYQERHALSRMIGAPPGYVGHDAGGQLTEALRRKPFSILLFDEIEKSAKEILTVLLQLMDDGRITDGQGRVIDARNCIVVMTSNLGAEYLDRPNAANGKIDPTTRMMVEQALKDYFLPEFLNRINATIIFNRLTKMEIRRIVDVRLGEIQKRLQNNGRNVRIDCSPAVRDYLGSAGYSPAYGARPLARLIEKEVLNRLAVLLLRGAIKDGEVARVVMREGRITVEPNHQGSSEENSSEDDMEIDEIDAREAFGRRGVRDERDSDGDLDLYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4L5</accession>
    <name>A0A5N6K4L5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4L5"/>
    <dbReference type="OrthoDB" id="5408934at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="363" mass="39834" checksum="95D90F7F66D207BA" modified="2020-04-22" version="1">MDNPTYKKLEEERLLNSYGGSTYETSVASKKRSIMSFGRKKSYRASTRAPSVINSEQSSSPSSRLSESFKRLTGSSFFNIAKSSIESGRRSSPASLYTSSSGLTPPQTPHPASLAGTSTSYGGINLTSENLKIRLYYLETRSKWQDCGNARLTVTTPPPGMRQACAVDQGIERRIIVTRKPMKPDNPDEKVEVLLDVVLGANCFSMIGNKGVTCNVWEDVVGPNGEVGMVGGRLGEGKISGKISGGIHKWLEGHGRIGGYQGWILVWAFNGRDCMDIICRSLVVRGFSIPLGVIIFGKGVRMSNTLARERKVVRGRGWETNTERRDTDLSTKHNTNQPHQETGKRPYNLRGNLTSTGSLFKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4L8</accession>
    <name>A0A5N6K4L8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF1680-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_002660</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4L8"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049174">
        <property type="entry name" value="Beta-AFase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049049">
        <property type="entry name" value="Beta-AFase-like_GH127_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012878">
        <property type="entry name" value="Beta-AFase-like_GH127_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049046">
        <property type="entry name" value="Beta-AFase-like_GH127_middle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43465">
        <property type="entry name" value="DUF1680 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G08910)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43465:SF2">
        <property type="entry name" value="DUF1680 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G08910)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07944">
        <property type="entry name" value="Beta-AFase-like_GH127_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20737">
        <property type="entry name" value="Glyco_hydro127C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20736">
        <property type="entry name" value="Glyco_hydro127M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 catalytic" evidence="1">
        <location>
            <begin position="15"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 middle" evidence="2">
        <location>
            <begin position="407"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 C-terminal" evidence="3">
        <location>
            <begin position="510"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8297306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="625" mass="71702" checksum="FA5FDFD6867A3DAE" modified="2020-04-22" version="1">MAYPQNSYLQTTFTTPGFISRRRETVHSTTLLYQLNVLKTTGRYDAFQLQWHPSYNDEPDVWPVPNHLFWDSDVAKWIEGACYFLQYEKNKEIEAAVGELVDMIRSAQQDDGYLNIHFTVVEPGKRFTNLRDLHELYNAGHLIEAALAHNQHYGNDLLLEPILKYVGLLAATFGPDPGQKHGYPGHPEIELSLLRLYEKTGDPRHLGLARYFIDERGNPKGQDGRHYYDAEAEERGDRPNEMPKYFPEKRSYWYQQAHKPIVEQETIEGHAVRAMYLLTAVSDLVRVDKSGDRERKRKAVERLWNNMVQKKMYLTGGIGAIKQWEGFGIDYFLPSGTDEGGCYSETCAAIGVMMLAERILQLDLDGKYADIMELCFYNAVSTGMLLGYIGGYLWTSSKDERKNAAEINVHMYTSAVLKIQLGEHTVELEQKTDWPWDGKIQFDLKTPHEISATIRIRIPGWASNWTILPELEGYSSELSKGYLTIPPEYLKTHSNFQLHIPLEPRYISPHPYTNQNIVALARGPIVYCAEDHDNPWVNDHFKSLVFSTRGEITEKDADVNNEPYKQLTALGAATRFRLPEQARPDLGHNVDGFSEVDIEELHFIPYALRDNRGGKGHMRVGLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4M0</accession>
    <name>A0A5N6K4M0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">NADH-ubiquinone oxidoreductase B12 subunit family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_002689</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFB3 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4M0"/>
    <dbReference type="OrthoDB" id="521512at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012576">
        <property type="entry name" value="NDUFB3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15082:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15082">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08122">
        <property type="entry name" value="NDUF_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8297342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="95" mass="10482" checksum="43A092634E5EB761" modified="2020-04-22" version="1">MQCTRILRAAQRANLTGFDPKALAAATGKNAGDPWARREAWRYQGQYSRRNRFANSFPGLGIATVAFAAYCGFEYFFLADDHHGHADGGHGEGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4M2</accession>
    <name>A0A5N6K4M2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_002628</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4M2"/>
    <dbReference type="OrthoDB" id="294295at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF12">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_1G14540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8297263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="256" mass="26433" checksum="7CFB733FE27EF979" modified="2020-04-22" version="1">MSRYDTELQDFPSLFSLKGKIAVVTGGSRGLGLHAASAFLQAGCSTVYITSRKASACEAAVSTLNALPNLSPGAKAISVPADISTIEGIQHLVSEVSKTTDHIDILFANAGATWGEKFDTHPDDAFAKVMNLNVKSVFGTVRLFAPLLQASATHESPSRVIVTASVAGLGVAPPGPNSAIGYSASKAAAIHLTKTLAVQLGPRQILCNSISPGFFPSKMANALLEKKGGAQKTGQGESKWEVGQTGGYRGCSGLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4M3</accession>
    <name>A0A5N6K4M3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribosomal protein L11 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_002675</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4M3"/>
    <dbReference type="SMR" id="A0A5N6K4M3"/>
    <dbReference type="OrthoDB" id="1478556at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_uL11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="8">
        <location>
            <begin position="13"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="7">
        <location>
            <begin position="74"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8297325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="17769" checksum="90AA4CFC82597D9A" modified="2020-04-22" version="1">MPPKLDPNEIKIIHLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVRLTIQNRQAAVSVVPSASSLVIKALKEPPRDRKKEKNIKHSKSITLDEVIEIARTMRFKSLAKELKGTVKEILGTAFSVGCQVDGRSPKDVSDDIESGEIEIPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K536</accession>
    <name>A0A5N6K536_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K536"/>
    <dbReference type="OrthoDB" id="9909311at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="319" mass="34343" checksum="521055B07A83559F" modified="2020-04-22" version="1">MAINIDSSKSSGSRTSNVVSPTSPLQSPLLLASAKSSEDLRSHHMHDSLNSYFDFTQAPNYKQHSNSHSTASLSSAFTDNNPSSFSGGPTSPTTPFAFSPDGSTGSWMPSQQSRVTPQLKNNENSNTGENLNNEMDANDLGSNFQRPRSQTFPTLAIDPSFIASQGTDPMTPKYNLPDTAPSSAVESPVHELGPPFGLDSAISPRSLHHSSSNSSMAHPPASLTPISGLQSPPHLSTPNSPTQDDARRALDTLLNFFQQAPTGLVDQNEYLTVLKLTEKLRIQQQNPGPLPGGLHRISEQEQECESQPQNMKMEQSTAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6N9</accession>
    <name>A0A5N6K6N9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6N9"/>
    <dbReference type="OrthoDB" id="289162at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008728">
        <property type="entry name" value="Elongator_complex_protein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05625">
        <property type="entry name" value="PAXNEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="129" mass="13736" checksum="B300EE4D174E2C92" modified="2020-04-22" version="1">MLTLPLPLHPRTSALTKWIELLSDGVLEIAPFPSIAIVPKAAPSSSSNPAQEEPPQGMLKIHRLPIFHEKGGGSAGFAGDDLAFSLSRRKGLVIKPYSLPPVEDEGEEQKGGIEIDGKGGKATKVDIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6Q3</accession>
    <name>A0A5N6K6Q3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PI-PLC Y-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5416983at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="892"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1222"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="508"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="617"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="689"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="703"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="744"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="764"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="893"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="930"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="948"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1001"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1250"/>
            <end position="1267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1296" mass="139997" checksum="D2B0A812E5F774FE" modified="2020-04-22" version="1">MMATEATPENFATPSKTPDHELNTIETKSQDVPSEQTLSIDGNNVTVDKDGIKQNSDLLEPTNNSAEVSVSGGSDTEVTKAETSKIGDEKGGHIRSTSAVKKPVPSFKAVSVNKTFLASKASTAVTPSKLGDKGPTVSTTAPTTLTASTSSTLKPRLVAKTGSSLRDSTPRASNTANGGKAGGAPDASAVWNKNRPAPPPEPKRFTDEELKQRYGIHLATRLQSDDPGKQANWADIDDDDDDWAPESIEWTDGTKITLPHADDAPPPPPEPVPEPAPVVKEIKKSEPAPKPSKSPTPQVIAAPAPRLGSGKAGLILKGAPEKPTLVAKPPGPPTPVKSPWAQLPPVEKVAPVAIEISQHTQHQPQQNRFNQRDPHGFSGMPPPPAKEIAADDFSRTWRDGNAHASRELYNSQSGRYEPVNEARRGVPRSDGQSRGPAVLQRPSHHDGPAEPSAAFQTHHTSGQQGSYGRRRTSSNVSGGSGNFARRMSRGHDMPPPHDTLSARRGSLAAQHQQRGYQNQNQAWQPRASSVVSHQSPHSTYGQLAPSPGGDIHMHGQGPPQGPPTSSAPKADVLEEQKNIMRRTRELAIKRRQEAEAKEEAERKERIRIKLEAMGPPPEKKKVKDDLAKEETVPTSIQAREENPIPPTKVAETSNDAHAPKPDVASENLNARHIEGNATESDLRPNGVFQQNASASAQQAIPDNRNSQSWQRNSASNYPTDRFTSWSAAPPPPQNSSRIWGPPTNEKTIGNGTFNPELNRLPEMSRQSLSDMSHSSAHPGPIGPPGANRGNGPYQANRGRDQYNSRPPPIGPPSVNKAPQPSRSYEEEQRRAVARSVWGGVSDRISQEDAILHQQQEELERRRGLEAAGMIENLSQPTYEDTWKQVVLNEDGTRSNTKNVSTTFIEGGSSSTSTLTENMSRGNARPELSRPQYSNNSWPSGQETSAANAHRESKFFPNNHRDVRLEEMNGHGFERSSSPSPPPPTMAGHPAYDSDFARPHVALPPPLPVVRLPPPVVVTPTPPPRPQSFAAAAAAPAVPAISQIPGLAARHGLTRAGSTSYDIRRGPTPSTQTGEWKDKIDQLFGKKSPPRTHALAVDSSSRRVFDHSLEPQASATVSLPGSINDNLIEEEELLDTKPAAEECFEEQEMGSLPVIKIPQIAPENAFQPATAPPRNIPRRFLISDTTSADPIQFPTETSNNTSVLVIMLPGQEKFKSIHFTAFHARSNPRRGRGGSRQTSSTHPRGGRGTRDVNNGPSSTPRDTQSPNPSNTSSRGRGGRGFGNNSNWNRHVTTPIHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6Q8</accession>
    <name>A0A5N6K6Q8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6Q8"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050723">
        <property type="entry name" value="CFA/CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667:SF2">
        <property type="entry name" value="FATTY ACID C-METHYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8298209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="601" mass="67483" checksum="7E041286288E6369" modified="2020-04-22" version="1">MSEIQSEIQVKAHEIYPAQISLLYSLPLYSTTLTNILRSFGIYHRPWLSYFCPFSSGTIKYLEANISNPILPSYHYSKKCPFNTRHQTIYRIQPTLFIRAGRQFNNSLEFLVLIFPTKLCCQATIMASYLSDVVTAPITKSADYLKSTIGGLTWGPALAVSKAAVTSLFGRIERGTLLVTDAETGKTICYGAKIAKEHKTNGVNGHYSSRKAGAARKIELRVINQAFWVRLFLFADMGFAESYMLGEVECDDLTGFFELFIQNRDQLSNATTLTSSIAATITGLARSTNTLSNSLLNVSAHYDISNEMFAAFLSEDMTYSCPIWKPISSSSELEEETLEDAQRTKLNRFIDGAQIKPSDHVLEIGTGWGSFAIQAVRRTGCRVTSLTLSIEQKALAEKRIFAAGFADKIEVKLMDYRALPIPRQPYDKIISIEMLEAVGAEYLETYFSCIHRLLKPDGIAVFQCITMPEGRYEAYAKGEDFIRKYIFPGGHLPSITQLIDNISKASEGTLVVEKVENIGGHYAKTLRLWKEKFLKNFESRIRPALMAEHEGMGEKEVEVFRKKWEYYFTYCEAGFATKTLGDAIITVGREGALELMDDIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K710</accession>
    <name>A0A5N6K710_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tetratricopeptide repeat protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002053</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K710"/>
    <dbReference type="OrthoDB" id="1872379at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052769">
        <property type="entry name" value="TPR_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13428">
        <property type="entry name" value="TPR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8298326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="31204" checksum="28D8F57DFA1C6E3A" modified="2020-04-22" version="1">MTTRTEKFQRKPRDADSEPAEAEEILRFPPEEEASLLAESNTLKATANALFAQQSYKEAIDTYERALSTCPKYLEYERAVLKSNVAACHLKLEEWKEAAKASSEALDGLEKLKKDEEKEKEGNVEETVKKEEVKEEEEADEEIISQGAAKSENTRGKDIDDAKESRAKDIERIRAKALMRRARARSEQDGWSTLAGAIEDYKLLSTFTNLSAVDRKTVETQLRLLPPRSKTAQDREMGEMMGKLKQVSLIDSYNFQMVKDEKTGGYSMNFNQGGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K726</accession>
    <name>A0A5N6K726_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_001876</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K726"/>
    <dbReference type="OrthoDB" id="5376590at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051169">
        <property type="entry name" value="NADH-Q_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42913:SF3">
        <property type="entry name" value="64 KDA MITOCHONDRIAL NADH DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42913">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="7">
        <location>
            <begin position="167"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8298117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="284" mass="31397" checksum="6FCC563FF6797750" modified="2020-04-22" version="1">MLLRRPASSLVRIGVNQSSLLRRSASSSFNQSTLPFSSQLCRSFSTNPKRSLTAITNQTKCTKFPRTQNIRFVSGKPLPQPRSKALNFLYRSATLLGGSLIILGVGVIGFFVYDATTYREDLSYSDISISKLALSPRRGGPKNLPIAEVQIDDDDSDEMQKQKDKPKLVILGGGWGSVALLKTLNPDDYHITLVSPTNYFLFTPMLPSATVGTLEFRSLVEPIRRIITRVKGHFIRATAEEIEFSEKLVELAGKSPDGKEVRFYLPYDKLVIGVGSTTNPHGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8S4</accession>
    <name>A0A5N6K8S4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="3">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_001291</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type-1 OGG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="3"/>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8S4"/>
    <dbReference type="OrthoDB" id="238681at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034039">
        <property type="term" value="F:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1670.10:FF:000005">
        <property type="entry name" value="N-glycosylase/DNA lyase OGG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012904">
        <property type="entry name" value="OGG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052054">
        <property type="entry name" value="Oxidative_DNA_repair_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242">
        <property type="entry name" value="8-OXOGUANINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242:SF2">
        <property type="entry name" value="N-GLYCOSYLASE_DNA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07934">
        <property type="entry name" value="OGG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="13">
        <location>
            <begin position="88"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="331"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8299192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="403" mass="45686" checksum="622B4CF563AA2CA6" modified="2020-04-22" version="1">MKIAGLVHYMAAYFLLNKTRPISITGELGEDEETESLLRHYLNLSPNLTELYEQWSLVDPNFKKRAPKFTGVRILKQDAWEALVGFICSSNNNIIRISQMVNNLCLHYGPLIGHLNDQPFHDFPKPEALTGPGVESHLRTLGFGYRAKYIAQTASIVASKPKGWLENLRNPETFDRPFEGEIPAGGRPGYRKAHEELLELQGVGPKVADCVCLMGLGWGEAVPVDTHVWQIAQRDYKFGKGKHKSLTKATYDAIGDHFRGLWGKEAGWAHSVLFAADLKTFSDKLTTKVEVKADEVEVKKENGEILEEKVTIKREYPSEMEIKEEEEIEIKRENGTEDNEVKEKVKVSKPSARSERAKRRKFVTFGRSHPITFQIVEPEHFPLKLGSQNDPCRNIEQHTSPHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8S9</accession>
    <name>A0A5N6K8S9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001234</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8S9"/>
    <dbReference type="OrthoDB" id="5329403at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="161" mass="17002" checksum="BBF54C80FD3BDF4C" modified="2020-04-22" version="1">MPPANGASKVMQNRPRPAVAMPKGIVPALPLSYGKIQQKKLSIREKPKETIPPSTAPAVQAPINSISTTNAPHAHADRLIIEEKTFEVIKEPSKPVSATVADISSIAESLDGLSSTEGGVTIGSTGCEVEEKLVNVIDVKGEILGNIHLQPCHICKQGKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8T0</accession>
    <name>A0A5N6K8T0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4110 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8T0"/>
    <dbReference type="OrthoDB" id="4447at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025183">
        <property type="entry name" value="DUF4110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052588">
        <property type="entry name" value="Kelch_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063:SF1">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13422">
        <property type="entry name" value="DUF4110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4110" evidence="2">
        <location>
            <begin position="395"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="369"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8299177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="494" mass="55830" checksum="AF1EFCECDFB6F896" modified="2020-04-22" version="1">MTYYKNYIILFGGFQDTSQATKYLSDLWIYDTSNFIWHNPVLPPVTQKPDPRSSFTLLPHESGAVMYGGYSRVKTNVTGKQMKGGGMAMRNVLKPMVHQDCFFLRITQPADTSTPTPPTVRWERRKKPANTPNPPRAGATMAYHKGRGIQFGGVHDVEESEEGIDSEFFNTLFAWNIERNRYFPLALRKPRAQKKSNAGNERGGRRGRGQANEEELLRNLAALETGKSLADADDMEIEKVKLDDEDADASPAKLVLTEFPHVRFNAQLAVQDDVLYIYGGTYEKGDREFTFDEMYALDLGKMDGVKEIFRREPENWLGSEEDSDDEDDDDEDDDEEDEEADAKLEDKKPLHTESTRKSKRKEKDSLAVDDTLASPSSSSTAPTFDDTPDSSPAAPEDNLPHPRPFESRRDFFQRTGNEWQEALMTALRWKGIQPETLSVKEIKTRAFEMSEEKWWDCREEITALEDEQEAAGIGEVVALGEREGGAGGGVGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8T4</accession>
    <name>A0A5N6K8T4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8T4"/>
    <dbReference type="OrthoDB" id="5329403at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="606"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="750" mass="82340" checksum="DDD28D13BD41F779" modified="2020-04-22" version="1">MPPANGASKVMQNRPRPAVAMPKGIVPALPLSYGKIQQKKLSIREKPKETIPPSTAPAVQAPINSISTTNAPHAHADRLIIEEKTFEVIKEPSKPVSATVADISSIAESLDGLSSTEGGVTIGSTGCEVEEKLVNVIDVKGDSQEEQHSAPSETQSTTSRSTYQMPPPFVPASNQSAMASESTQFPQQVAFNGQHPMHHAHPSSSTNPIFGGYPDSNNSSPAPPSTASNIPPYVYAQQGVMRHGPHLSNGGHQHHMPNGFSPMTPAFPPGYYHHHDAFQVPPTDEYLRRQMPPFNPSECYSPTGAPPIAESPRFNGFDPTSAHNVHASRSSAQMDQENGLGPHYGHHPSPIPPMGPPPYRGVIGYPRKEEIPWAAGNRRDLWFHLREQFAQPEFSDCVLELRYSDDRAPPLQISGHRLIFSRSLVLKGLITSGAQANCHSPQSNQSILIESDDRYLRSDAFSLAVRYLYGGPILDLDAMARFPAPYIGSAPVPSTPAERFNFTLGYVASGVALQIPQIWKTGCSIASQLITWDTAEKALEFALEGGIDWSWSSGNPDVNDVIGRSIYSPCANMLIYNIINLIILSIPPNFELDTTVSDPLFNSRIPHVPDDRPTPANPRLSSIKFGDHPTEESLRSPSSDPITTTLSRLLLNLPFGPLKHVLETGNSGLIHGQATHLLRRKIMYPVIEEREKRRQRAFASKVPYEERVKNGRQWNAVGWKEAVLPFDDHRNEEVPCLRKTWVGFTNAESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8T7</accession>
    <name>A0A5N6K8T7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8T7"/>
    <dbReference type="OrthoDB" id="10440261at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="149" mass="16954" checksum="F82717FC46B1E1B4" modified="2020-04-22" version="1">MMSGKRKEKASERQRSGSDGELLSNKEEERGNEDEKRRKTWANLGRMPNFRKAPIVEAPTNGEEEPAVESESHRLEREQERERRNMDRRTNWSDADLDGHKDESADQGGCSSDSANGIMIADPKVKADAKERASKFCIFTRALSSKKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8U5</accession>
    <name>A0A5N6K8U5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8U5"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="322" mass="35416" checksum="94BAB6DD3F64C1BC" modified="2020-04-22" version="1">MLKATFIDDVPKPLFVHPGIKVYGVESVRSLGDGSYFLYLAYLASCLQLTTIFISYSIASHFENLSYYTQLPSPRHSIASSHCIPSSTSILSAHARLPLTTWPILSSAILYHFLISSSSPNPQAFLPAIEHRYGLFVRNFVNSVVCLKKPPPTHPPLKAPTGFLTGKGLSPTGATLLALIEKLLAAAEAPFARSILLAGVKMRDAIVINIGEGGVEISIALLRPGGGAEFFNWRMFCRRLIKLCLELSPVAGKILPEARINFWARQCASQRDGKTNHCGVDYTILYHPDNIFSRIESAIDQTFFNFTSLPLAIERNPNIRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8U9</accession>
    <name>A0A5N6K8U9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_001315</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8U9"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000037">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF103">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSIDASE MNL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="446"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="532"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="366"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8299222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="541" mass="60723" checksum="9DCAFFA5781EBEB1" modified="2020-04-22" version="1">MAPSSQGFGKMDRRPSCVKFDIWGVFAFSQYGLFSSPPAYLPLPPTGRYSIQAKQFPRESRPARAVRLTRQRKVREEFLHAWKGYKKNAWMHDEVMPLSGGQKDTFVGWAATLVDSLDTLYIMGLKEEFEEALESLKQIDFSKPNAERVPVFETTIRYLGGLLGAWDISGHQYPILLEKAKQLGDFLFRAFNTESGIPTPYYWWEKELPKGDTIPGENGVLVAQIASLSLEFIRLSQVTGDLKYENAIQKITDQLDNTQNTTTLPGMWPSQANCMGPNLTFASRSFTLGAFADSAFEYLPKTHLILPKSTPAEQYLRMYRTALSTINEHLVFRPNLPGDPDILFSGTVNVNSGKPLLNAQVQHLGCFVGGMVGLGSRISNSTSELETAIKLTKGCIWAYENTPTGIMPEIFHANPCANTSSCTWTGPATDSGFARIDDPSYQLRPEAIESVFIMYRLTGDRSWQEKGWKMYRAIVKHTHTSIANARIQNVMSAKPEKGDSMESFWLAETLKYFFLLFGEPDVVSLDEWVLNTEAHPLRQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K940</accession>
    <name>A0A5N6K940_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">EYC80_001335</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the SWR1 chromatin-remodeling complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="372624at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18003">
        <property type="entry name" value="DEXQc_SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000005">
        <property type="entry name" value="Photoperiod-independent early flowering 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000655">
        <property type="entry name" value="Protein PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF1">
        <property type="entry name" value="HELICASE SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0010">Activator</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSA" evidence="19">
        <location>
            <begin position="319"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="750"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="1291"/>
            <end position="1441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="438"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="675"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1509"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1585"/>
            <end position="1608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="495"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="532"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="675"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="713"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1520"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="1591"/>
            <end position="1608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAB8299246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1608" mass="181907" checksum="B2A8A9CA4C58A4DF" modified="2020-04-22" version="1">MTTASEAPENIPPTEDVPQTPKANGHAIENGDGDGPPSKRRRLSSETKTIPKRKPESPPWKKVLAEGPTSFTVDGKRKSGRVNQIPLELQPQSEKRTTRGAAQKAVTSKSKHGNSNGIHSSSNRDASTTLGTSQTSKKFTSQNLSKSPNKPSTSPKRSHRKSIPSEQNSTQARSGNKKSIVSKDSQSTPTYSRLRRSGRASEVMQNDLASSSPATTAEGMADQTPKSTPTKIRLRLKPATFPVLHRDDTFPKPPKFPSFSEFYEWGLHVPVIEGGLYIPEDAVEYTEDDIKMDAQTMIRLEDAVKPGGVLANSTIMNHPEKQDPMPPQYAHQDHLVKAALHFRILMIREQREHLRLAKQLAEACRDEWVRRQPKSHEQLEAEERKASEARYKSVLKSLLGTWENVKIEVNRRRLIEWEAQEQARVRKALNEAVDISTQKLQARRAQHDSEEEDTDEEDNEDENANDDSNNDNGSDSEPNDYESNMSSSESEAEEETAKHEDEQLTVDQLREKYAALPDIAPASGDKQMVGDGSEDEGTESDPSIDMDDDTDSSDEEEDSDEEDVNEADDGGRTDLLGFLLPSDIKELETKQAELGPVEQSVEPMDKYLTPVIPKDVMVLDVEDSEAPPALNGESIQPSVDGISRKSPLIEEIPMSDQHDIPSKANYLLSPDQFQENTAMSPDRSSQPTPRTTETKPSEIDSASSVDLHHTSRRNTQSATPQPSNGLKTPVPFLLRGTLREYQHYGLDWLAGLYANNTNGILADEMGLGKTIQTIALLAHLACEHEVWGPHLVIVPTSVMLNWEMEFKKWCPGFKILTYYGNQEERKRKRAGWKDDDAWNVCITSYQLVIQDQQVFKRRQWHYMILDEAHNIKNFQSQRWQTMLNFNTRARLLLTGTPLQNNLTELWSLLYFLMPSDGSEQGVGGFANLKEFQDWFKKPTEQILEHGREQMDDESKAIISKLHKVLRPYLLRRLKADVEKQMPGKYEHVEFCRLSKRQRELYDSFLSRNDTRDTLASGNYLSIINCLMQLRKVCNHPDLFLDRPIMTSFPMEKSAITDFEIKDLLIRRKMFRQEPMTKVSLDFLNLVPTKHESLSGVLASEINRLSARRALEVMREAQRTRAQNAFTNLDPSTVKSNLVYLESASRWGRFEELQHCVYLNALRRQQKPIYGSSLIERLDLRLDKRPLQAKPKRRTKLIEWLEDSSPIMTSMIPTFASRSQDLHTTIQKFACVTPPVVARDMTSVMFTPKGVSNFQSTVATRETDPFHEARMRLSIQFPDKRLLQYDCGKLQTLDKLLRKLQAGGHRALIFTQMTKVLDILEQFLNIHGHKYLRLDGATKIEQRQILTDRFNNDTRILAFILSSRSGGLGINLTGADTVIFYDLDWNPAMDKQCQDRCHRIGQTRDVHIYRLVSEHTIEANILRKANQKRMLDDVVIQEGEFTTDYFNKINVRDVIGEEESSLMEGDAAANAAMDRVLGGPDNDKDVRRVFAQAEDREDVAAARVAEREIVQTDAADFDENAATASATPGGAGTPAEGAPTPGADGTPTAEDLMEIDEDELNAWGQQVGSMDDYMLKFMSIQLADAPIEFPRDKKKGKKGKDHRNRHRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K941</accession>
    <name>A0A5N6K941_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_001324</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K941"/>
    <dbReference type="OrthoDB" id="199599at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052053">
        <property type="entry name" value="IM_YidH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187:SF2">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187">
        <property type="entry name" value="FGR18P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="DUF202" evidence="8">
        <location>
            <begin position="324"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="96"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="143"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="234"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="514"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="781"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="915"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1091"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="604"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="532"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="555"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="781"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="917"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1091"/>
            <end position="1108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8299233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1142" mass="130524" checksum="999EAED7AA5B679B" modified="2020-04-22" version="1">MDRDASLSTRERERGGDNSQIPQSQTSRISQNKVKVPADQRGNDNVDEILQKDLNRIPADSTDISQLRSNTPNTSSTSNANIEAGLGLNIYAERQRHNSSPGGRTDNASGSRSGGAKGSLRIQEGKRQRIDSILEEARNRKVAMNTNTGRGEGGEGVDVDVGSGRRGGGEESLSPRTRGNGFDNGKWNGNRNGNEYVIGRESRAESSADEETSVLRRGSDINYGGVGVGTTTSITANANSGHNSTKRKSGTNTNDKRGVWGTRRGRGYGAGDETAGNNDRAANGCENGGDEHDGKSSGKIGNWWKKMTEEYGSIELENKGSVARDHLALERTFLAWLRTSLAFASIGIAITQLFRLNTSSTSSTPAHSDATIHLRHLGKPLGATFVGISILMLSRKVQKGFEGYVIVHNGFDAWVAWDCVGFVRIAYNEDGDEDTVEEPYTLCRVFIIDIGLQLELELQFELSLFMRSFGVLLVGNASTVHEMQMRNWVDGPVIDQRTEAQGEDDIPIIRTSRQHMQPTREAAPDHSPDTITPVQPSSIVQQPPSTPSYRNLRRVQRDLRESRERERENCSGDLHHDRDHYRENRTKNPIMPLDNALLISQAENTTLQKENRELKCALKEAKDTVAGQKDEMLRDKEEGEMLGREIVLEYARERAKWMNAMWDLKWLISEKDTLEAWRQWGKGMRRMLEEEQGKWAEILAEGQKRESKEGVKDRKYRVRVKRGENGMPYTVFEYGDPRNDPLDMDEIFDASKHWMRVEVAEEKYGGMVRKREMDREIEEKRKLEEERNPGEAKRLREAKKQEEARKLEEVPDSGEAEIEITGTGAIAHLISLVHRPATHNVPASGDLFPQSSQATKIAHSIPLVLRPAVTEIPVQQPFTIEVPLHTRNLCRRLRQVHRKFRETLKERRIERKRKLSRERSRERWRESDRKRERARRDESTTSDDFYNRYMEVDPVLIRRQIQYLHMDLYRSCGSLEGLTEMKPRDQGRMQILLEETLIKKLASELVVQRMRRMKDVENIKELIGEEHTVEAWKEWAKKMADKMDKDQEDWEECRKKRNLDERMHDGRERPPEYRTYSDFIWNHEIDRAVEEAEREAEKEAEKNAKREAEDDELDSVRHAMRGMSKELIKEEAGGVVEKVEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K943</accession>
    <name>A0A5N6K943_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K943"/>
    <dbReference type="OrthoDB" id="5215911at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="76" mass="8537" checksum="301AE0E9B47C62C8" modified="2020-04-22" version="1">MIPQPTSCGGDPPLWSRWKTYYQLFLVLLVACVLRLGENILGAAWETISKDTHVSFTNMNGRGALNYLLLGFCNIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K946</accession>
    <name>A0A5N6K946_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K946"/>
    <dbReference type="OrthoDB" id="67317at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8298981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="71" mass="8036" checksum="9895FBE11BA1189F" modified="2020-04-22" version="1">MEWRMVLVIVGHLIDGKYSYEETRRDLDPSKFNCGLIKLSCLSLNLIGLISGTCGRAPRPLAFLLNMIILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K948</accession>
    <name>A0A5N6K948_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K948"/>
    <dbReference type="OrthoDB" id="2993351at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="155" mass="17829" checksum="B265C41BCDDF426F" modified="2020-04-22" version="1">MKGFGWQEMEDVIIDVWISSSKPTMKRYRWVFPGKDGFEITKGEGVLREYHFGRRTMVHRGFRYHTPKGTDVGINVNTLQDIDQWSLTVHKYNGLDHEPQYNAPKHTGELPTSKFEDEKRYPGAYHCGAVTLAFTAICSRPTGRNHHLLPAPRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K955</accession>
    <name>A0A5N6K955_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">EYC80_001367</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K955"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.270:FF:000006">
        <property type="entry name" value="Similar to DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048761">
        <property type="entry name" value="SMUBP-2_HCS1_1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21138">
        <property type="entry name" value="SMUBP-2_HCS1_1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase SMUBP-2/HCS1 1B" evidence="14">
        <location>
            <begin position="15"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="12">
        <location>
            <begin position="287"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="13">
        <location>
            <begin position="424"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="67"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF21138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAB8299290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="665" mass="72706" checksum="2A94724F024CBF1D" modified="2020-04-22" version="1">MALALKSVDVPSFCTTQLHLLDQELQIELSETSNIITGTSPTSLQRAGLAITNLVLISQRTGLGGKTVIELGPDPATSSSGSGGKGKSGGGGSGEGELQEHGIRVGDIVAISEQPSGSAKKREVKELEEKGSRGVITKVGKNAVCVALDENGKGEENVGGMKRCWVVKLANDVTYKRMNGTIGKLGKMQEAEYSNFIRVLFGLSSPSPVPEDLGNAELEWIDSSLNDSQKHAIKFALASKEIALIHGPPGVMISPFIFTKWHPARLLPSVVNHSLDVLTQTSEAAAIVQDVRKEMDSKQASIKKTKSGRERKAIYGDLKELRKEFREREKKCVNTLVGGSKVVLATLHGAGGFQLRDEKFDVVIIDEASQALEAQCWVPLLSASKVVLAGDHLQLPPTIKSLNSKVKTKPQDTDTESIMRGMTLETTLFDRLLKLHGAGIKVMLTVQYRMHDKIMRFPSDELYESKLVAAEAVKARLLTELPYDVEETEDTIEPLIFFDTQGGDFPEKSEEESIDKKAGRGLLGESKSNEMEMALVRRHVQNLVDAGLKPEDIAVVTPYNAQLALMSRSMKEAFPGIELGSVDGFQGREKEAIIVSLVRSNSEHEVGFLGEKRRLNVAMTRPRRSLTIIGDSETVSKGSRFLKRWMDFLEENADLRYPSVAELNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K961</accession>
    <name>A0A5N6K961_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K961"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="121" mass="14265" checksum="895A703104E8EA4B" modified="2020-04-22" version="1">MLMVWLLPRDTTRYKGVYCVHFEGMGGRLWVPYFSMMNGYVKRSMRSMRSLFKTCLQRVVHKIFFLLHAIYPGCLNAILRDLNQMLLPFHNICFSCSSKENSHRPSTKIVQRFSLHSLRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAD7</accession>
    <name>A0A5N6KAD7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAD7"/>
    <dbReference type="OrthoDB" id="3501324at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="88" mass="10246" checksum="60B58A9CB375119C" modified="2020-04-22" version="1">MHSSTSHIVPSPRRNSPPIIAPIHQDQMKERGASFEPESRTPRTLVSNWLSSISSSTGRKEQSREQEVFWKKTRSWGRRTKPKMESWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAE4</accession>
    <name>A0A5N6KAE4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Checkpoint forkhead associated with RING domains-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">EYC80_000393</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DMA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAE4"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031578">
        <property type="term" value="P:mitotic spindle orientation checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051865">
        <property type="term" value="P:protein autoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097271">
        <property type="term" value="P:protein localization to bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090337">
        <property type="term" value="P:regulation of formin-nucleated actin cable assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000921">
        <property type="term" value="P:septin ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000426">
        <property type="entry name" value="DMA1p Ubiquitin-protein ligase (E3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.20:FF:000030">
        <property type="entry name" value="FHA domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15067:SF7">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE DMA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15067">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17123">
        <property type="entry name" value="zf-RING_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FHA" evidence="15">
        <location>
            <begin position="267"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="16">
        <location>
            <begin position="415"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="66"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="568"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="71"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="115"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="569"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00061209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00080465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAB8300166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="683" mass="72098" checksum="7EB60D29280C4A96" modified="2020-04-22" version="1">MYSSVPSSPWNPTTTPISSLVERASSANPVSPSSPPPVSPSSPTSRGRLRGLSYLRSYTHNHILSRENHNHNSNSSTNNQNSRPVISRNTSYPNNSPSSPTSASAIASPASPTTENLPRQTLLTVQRSTNTPELISAGTTNTQENLGSTSGWLPTVGGHSGVSRIATQPQSTATASSSAVLSGNDPSAVTSGLAASMARTRSAGTGGAADMPLLNNLGENSPASAGGSMSHQLPSIRFSPHQDPRAHRPSLIFGTMSRTLPTGKEVIKVGRYSERDNQPPQASNVPSFAPVGFKSKVVSRRHCEFWCAGGRWYIRDVKSSSGTFLNHIRLSSPGTESRPYPVNDGDIVQLGIDFKGGEEMIFRCVKIRVELNKGWQTGPSSFNVQSHKRLRELNNNQKKPSVAGSSASNGSSQDCSICLGAIAPCQSLFVAPCSHTWHYKCIRVVINGPTWPHFICPNCRTVADLEAELDEPDGDWEELAASDEEVDAVPEPAANVTTPHNTEPAAEEAAIPQATNLAAAPSLPEPEAFEASDVHHTEDDLDTSDESSTGPHIHEAGIEDIAFLHVDDSPASSTSATPTPQVNNNSTVPPVDIITRKPVPSASAASSSRVEHVRGSPSANGIHPALTDPLTGEGPMTPRNDVGPFIFDGGAGRTNGLRLASGVGNLDYNDTPTTAHATPHSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAE6</accession>
    <name>A0A5N6KAE6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAE6"/>
    <dbReference type="OrthoDB" id="1922977at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019607">
        <property type="entry name" value="Putative_zinc-finger_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039278">
        <property type="entry name" value="Red1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21563">
        <property type="entry name" value="ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21563:SF3">
        <property type="entry name" value="ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10650">
        <property type="entry name" value="zf-C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative zinc-finger" evidence="2">
        <location>
            <begin position="1183"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="849"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="416"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="555"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="686"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="698"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="865"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="884"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="925"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="951"/>
            <end position="967"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1250" mass="136025" checksum="13C32A37BAF26303" modified="2020-04-22" version="1">MSDYPYYGATYGRDQTNNPPYPTYPTQAPYYQQDDGRSGQHAMTQAYDNAMAYGYNQQLPNYSAPAMQNNIPQPPVFQGWNQENTSMPQYNAAPQAMHSYAGYNHQNYAQNSQYYAPVAAPQPTYHSQTPMYGNPGDREMSEGEYDDNSAHMHAAPPSTTVGAPGTSNYRGNDGNGYIDTAHRAVYSNSQDHTLPRPPTLHNADYYTQSQPLDSYSPYVPQSEPMFGQVKNTQNQGTGASKEVSKTNNDKKKKEGPQKKENTRAPVEEPKYASSKSGPEVLPSSSKGPASGTSQGSNPTQADTPNSNLTFKSVGEARKKAEGAILNLWSYDIRFPAYIEEGVDEKLVGELFDDLRLSKTASKTVSAASAQSPSTSISSAPTSALPANGVQSNGQVPAQNSSTDKPKQAVLNGTVPSNSAATQQSKSAAAVEKEKTMQAKMDALRKSRAERAQKNAAKSVSTPALVTLPNSLAQAKPAVIPAMPPSVSTPTSCPEDTTEKNKVGIMDKSSSTQVPALTVATQFPKSNAPPPAIQQASQKIPGLFLASAAPTPPPVQQQQQQQQQQQQQQQQQQQQQQQQQQQPLVPTPAPTGQRKRPVAADFDGPSTSVTPFKRPFGQSRNEQQPFVIDVSEDEDDSDEDVEMELESQADTESPTLPTGKLSDQKALPTASSFLPPKPFTPPPISSASTLPTLQTSVKPHPEDLRRKESEIEQLKRKIAEAEMRKANKRSSSGAQTPVNNITSSSSNIGVAVNKAETSTEIQKITGVSKDKSKSDQQLAVAQAAELQKAADVREQEAEAKRIRREKIASAIPRVDAEALQNQAKLEELRAETARIEAAMQKNLQDKQKLIEEMERLGQETDQQLQEQKEKLDSLTREETKDNTAPRPTSTKPDCEPDSQNLTEFEPKLTFVPMEIDAQIADARDSAQPQPGQLQITSPIPQSSIQVNSNGDAVKESPEDCSVEAKEHSNTNQDLEAALQEAVRADADSTGPSDIEMDDSSNAGLVQVAEVNATPDEQKPSSDYSPVLERSQPLIASPNPDIPRVAEAPGVADIESDNYEPPEATPPVDETVSVESSPFSPAPPESVIDEPEDVYFGELSDGNSIDAEVDSNGVEQRLPVEHGGISHLTEEPVSSDLDKSNFFSPYQSPLRLFHAFRFHPQYKQQVSGGLKSMTYTNKIDAAKELCRYELMGGICNDDTCEFQHFREMGLPDDAILTVLGSPDEFAGEQRERFIEGLKSLLSDLRAKKDQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAE9</accession>
    <name>A0A5N6KAE9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAE9"/>
    <dbReference type="OrthoDB" id="10249045at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000964">
        <property type="term" value="P:mitochondrial RNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013943">
        <property type="entry name" value="Pet127"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31014">
        <property type="entry name" value="MITOCHONDRIAL TRANSLATION SYSTEM COMPONENT PET127-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31014:SF0">
        <property type="entry name" value="MITOCHONDRIAL TRANSLATION SYSTEM COMPONENT PET127-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08634">
        <property type="entry name" value="Pet127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="805"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="830"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="847"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="860"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="909"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="930"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="954"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="980"/>
            <end position="993"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1146" mass="129823" checksum="531965A3B6F65221" modified="2020-04-22" version="1">MFVSITRQTPKLQQPHVCTSCLSKLLGASDALPLYSNAILLRAPRNTATFSTTRRNNENDQQTETVVEDLKRLKIDPLNKDGNGDNQKTNDASAGSAEVGPGMKSLTKMLEKKKHEKKKKSVKTAKTAKSTKLDRKGKGGQKALLDAEEIIFEDQDKVETESAVRIKRVKQKLINYVNSNSDSPLIRHLNVPAEEKKQEKIAPSQLHSIYQSMVAEKGEAAARKDLVDLIQKGGLTTTDRTQVMKELRASLVNRPRPKGGSESETPSSSTNLAGMLASFESIHNHPIRKVAPKKLKAMEKKEKQTTKASVSTKGPKSIRTGPIKKSPGTSEFEVKSIDVDSLKLVPVQKKQPPVPGLSYGLERALFNPGVYHLQDPRSRVFNFDPYLQQIMPVNEFDFTALKQYVTSSRDKALIETAKDEKRKYTGSTSSMSASLAHFHFLLSQWRPINTGMLSQEFPVEFNSFTALQRGPSAIFLRERDGVYAIDADKQFDTANILSMLGKSMEKLLTLPKEEFEQYRKENSDSITEDQRNEVESFHYTTMGDFLMRSQLDAHDPRLPGTGMFDLKTRAVISIRMDIDNYAEGSGYEIFNRHGEFESFEREYYDMIRAAFLKYSLQVRMGRMDGIFVAYHNVERIFGFQYISLPEIDNTIHGTTDTTLGDSEFKLSVDLLNKALDRATARFPGKSLRLHFETRGNVETPFMYIFAEPMEEEDIQKIQDTNKAEIEAFESRVLGLHGAKGTAEEQLEEKKDAEWENLRAKIEESMENDEYEIKSAKEIAESLLEHHDVTGLTLDEVEQRVEEFLSTSSYNEHGEDEAIGENENKLWKEEENVDADEEGDEIIEGGEEIEHNVDMEKTTADVDEDADEENDDDSEEENEDEEDEEEEDDEEAVERDSENEIEDVTDDVKTSNFTEIVTEQSAIQEGLFVDPPEETSEAQQDNDEPLDADIREPELVENEDLLIDSAEETLDTDETSDEISNSEGSTADESQASSDPDETSDNTLVNFAESTVPEEDKPKEILAMHLAIRNKVNGEYTVRPEHLKATDNWTVEYALSEIPDPEKAMNLYKACQTRRKTALRKSDEPDNKWAEERNNKFIAHLKDLARKGRSWRQQTTQKEAGLPIKTLEFREEPKEVGVYERSEGNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAF2</accession>
    <name>A0A5N6KAF2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAR2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8299819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAF2"/>
    <dbReference type="OrthoDB" id="201752at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13778">
        <property type="entry name" value="Aar2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.550">
        <property type="entry name" value="Aar2, C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007946">
        <property type="entry name" value="AAR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033648">
        <property type="entry name" value="AAR2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038514">
        <property type="entry name" value="AAR2_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12689">
        <property type="entry name" value="A1 CISTRON SPLICING FACTOR AAR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12689:SF4">
        <property type="entry name" value="PROTEIN AAR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05282">
        <property type="entry name" value="AAR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAR2 C-terminal" evidence="1">
        <location>
            <begin position="65"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="255" mass="29421" checksum="A8BDD171111EEF63" modified="2020-04-22" version="1">MWRRLTSCVKHPYLKRVTGGKWNSWKVSSSHDIKTTELQVSSAPRDAKSGGTNFDGNDFLDFVFPRNSHTFSSMSSGRERTEQALDSSDHIIDVITRCTFEDSEEIIGELQFCYVTGMMLGNLACMEQWGIMFMYDEEGFETSIFDHDSHLGDELKIILTKFKSRLNEQLLSNGSSITREQEEVGNAFEAFESWLWKWGWDLRGNYLRSGKFQLEDGEMIDAELKDFEDEDERGEYAPIIVDLDEDGLEKDRIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCH3</accession>
    <name>A0A5N6KCH3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_002983</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCH3"/>
    <dbReference type="OrthoDB" id="5402974at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060962">
        <property type="term" value="P:regulation of ribosomal protein gene transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045178">
        <property type="entry name" value="Fhl1/FHA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21712">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN FHL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21712:SF29">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN FHL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="365"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Fork-head" evidence="6">
        <location>
            <begin position="713"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="3">
        <location>
            <begin position="713"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="78"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="476"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="549"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="792"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="897"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1095"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="481"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="587"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="642"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="840"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="898"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="949"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="980"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1106"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1135"/>
            <end position="1145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8301064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1155" mass="129085" checksum="AEF9A78D6F4FA28C" modified="2020-04-22" version="1">MTSSKTAETVTQPVAPVATMSTTTFINDNNPLGTHLTDPQDNAKYFFAEQDEAVTAAMDPTLPSNSTRQLEPLLENRNSSAAEGFDSAKGTEKSELSNHSDNKISSHPEEPLDSVMEHYDPKIEQDPNGKEAIDHNPEINTHSNIEPTAQLIQKHSQSPANRPLDTLPLCDISSALPGNDQMLSSNYEDTCQRDTGNIDPDDMFRGMCGVDESMGPDFKGRSWLPEHMNLANSGVQLDGFAKLLFDDSTFYMTTHEVIIGRDTVAQNNLLRYEKEQALIERAWNESGLGPDGSSQTAIDSNMPRQTIININPRAGILESWMSLHHEKRSRKGKKLKNQTSQIGTGARLPAASGNMPLQNPDPHSCPVVRVHPPFDKGLAGFKAISREHVRIFYDDHQDIFKVEFLGRNGGFVDGLFYEPKQVATLKSGSKLQMGFIYVTFALPDLVIDDTSFQYHDEAQEEAATGTIYSEGGKEMSLSFDDVPRAGDQRSTDNSECSSDYRNGYNVAELSDNEEERIEGGSILDFAGNSDNGLQDLEDEDNSLLDDLEHEEEKSIQEEPLVNQPIDTSPQPAKKRGPGRPPKNGVMSKREQQIAKKEALERERIQEEERAQEEQKAEDQAQGTASKTVPGKNKVGRPRKHPRPEVTEEGPPRQKRKYTKRQSGPKSPASPDEDKFDDDGNCIQAKSGSTRKVAYTLKEVSRNKADYTAERLEKPHRNYLQLVYELLEEAARPLCLPQIYNEMEVKFPYFLFQDSKGWQSSVRHNLGQHECFERTKRAGKGWAWTLKPGSSYMKEKKKKERSPPVAGGNQPIYQAGHPIPGYGVNQMQPPPGYMFNPQLYQSQMNPHQQQEHQQYQQGQPYMGHPNHHYAPYPMHQGYVPPPGIPAPFMPPMAPQLGGTAPASYSSPYAPKPPAATTQSQGHQQQPQGTQQPQGSQQPQGTQQPPPQQLQPPQHQYPQQQYSQQYPQQPQQPHYQPQGLPSHSNVSQAQVPQHQPRPSAGNSIQPPPQAIPQTAAAHTHQKRVIPPNLIAVVQGYRNHVVNLMRQKAPQSDAEALVDKAINRVYDGTEEDRSLDSTEHEMKLINGVLNVLKLPLVPRAPSASPGHTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPSQSSNNQNKPQVALLCPGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCI2</accession>
    <name>A0A5N6KCI2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCI2"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="131" mass="13492" checksum="D17B2B383785C8C7" modified="2020-04-22" version="1">MFSTSISNRVYKAISEPTTPAEPNPATEPIPPIKPSDPASIEENPHLVEQIPPSDVEVNPPTVETAPPANIAVDPPTSQTPNSNSNPPPSNSDSTPHIEAAPASSPTKPIEPTPPANIPGGNSNNNDAPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCI3</accession>
    <name>A0A5N6KCI3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Complex III subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_003013</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCRB/QCR7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCI3"/>
    <dbReference type="OrthoDB" id="425749at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1090.10">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003197">
        <property type="entry name" value="QCR7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036544">
        <property type="entry name" value="QCR7_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02271">
        <property type="entry name" value="UCR_14kD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81524">
        <property type="entry name" value="14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8301107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="117" mass="13074" checksum="B5B9444260F3C6FD" modified="2020-04-22" version="1">MHSLSLSIRTHNSPIMSAPSLASWIVKKPGLLKIMQPLASWYTNAAGYRQLGLRADDLLPEESEEVLLALKQLSSALSNINFCQKTNTPSLKKITHTFHPSLQKSKPKLRNVLIWSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCI6</accession>
    <name>A0A5N6KCI6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Fe-S cluster assembly protein Dre2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_003030</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCI6"/>
    <dbReference type="OrthoDB" id="311633at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11000:FF:000002">
        <property type="entry name" value="Fe-S cluster assembly protein DRE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11000">
        <property type="entry name" value="Fe-S cluster assembly protein Dre2, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031838">
        <property type="entry name" value="Dre2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16803">
        <property type="entry name" value="DRE2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S cluster assembly protein Dre2 N-terminal" evidence="9">
        <location>
            <begin position="28"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8301128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="195" mass="20902" checksum="99CA6C2989980F62" modified="2020-04-22" version="1">MAPSVTIDNTSDFSPITTTTKTTSFNPRTLLLAPPSIASHEEKLRDVLATHDRTVTDLQMLDRLSAGLVTLPESTYDLVLILTDADGTRAESTELLTRDVFGKITQALKAGAKLQAQDGTFGQEIDGAEYREAILAGLVAEGGVMLKPDHSASVAVPLRLRRKENNKSAAVSSAGPPVSAADVPLNVKRKRSWLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCI9</accession>
    <name>A0A5N6KCI9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MYG1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MYG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCI9"/>
    <dbReference type="OrthoDB" id="10265310at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003226">
        <property type="entry name" value="MYG1_exonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215">
        <property type="entry name" value="METAL DEPENDENT HYDROLASE - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215:SF1">
        <property type="entry name" value="MYG1 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03690">
        <property type="entry name" value="MYG1_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="28006" checksum="624A010410ACAD98" modified="2020-04-22" version="1">MHYGKAIIAQHLGVTEDAEEVGVIWKKIYENFIEALDAHDNGISVYDPKGISAAGLEKKFSDGGFSLGAMVSRLNPNWNDPTPSDPVEAQKAEDEKFLVASTRMGEEFSRDLDYYAKSWLPARAIVQQAYAKRLQYDSKGRILVFDGQSVPWKDHLYTLEDQENSENKVLYVLYPETPRPDAKWRIQCVPVTKDSFQSRKPLPEAWRGFRDEELSQITGIPGGVFVHAAGFIGGNTTFEGASQMAATAVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCK6</accession>
    <name>A0A5N6KCK6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Small ribosomal subunit protein uS7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_000673</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCK6"/>
    <dbReference type="OrthoDB" id="10264639at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14867">
        <property type="entry name" value="uS7_Eukaryote"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.455.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_uS7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005716">
        <property type="entry name" value="Ribosomal_uS7_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003106">
        <property type="entry name" value="PRK04027.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01028">
        <property type="entry name" value="uS7_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="5">
        <location>
            <begin position="64"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8300509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="213" mass="23732" checksum="E9B26C92990BFF6E" modified="2020-04-22" version="1">MSDGEIEVEAVSGYQVLPKEVTEEIGSIKLFNKWSYEDVEIRDISLTDYIQIRAPVYISHSAGRYAQKRFRKANCPIIERLTNSLMMNGRNNGKKLMAVRIVAHAFEIIHIMTDQNPIQVAVDAIVNCGPREDSTRIGSAGTVRRQAVDVSPLRRVNQAIALLTIGAREASFRNVKSIAECLAEELINAAKGSSNSYAIKKKDELERVAKSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCK7</accession>
    <name>A0A5N6KCK7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCK7"/>
    <dbReference type="OrthoDB" id="5341143at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="343" mass="39172" checksum="7837E809AC2345E9" modified="2020-04-22" version="1">MAMARQAELQKAPSAGHPRSGEDESHVIKTTKSRTQVYTLSQVISSPKNCREKAKKSVIVKPIAKNDVRKLQRIDKHAQYSRFSKNSYVVEPSPDPDNLASVLQESLEGARAQILNAGRTAFNEAYTVLMQKFVDQKATDHSFLEVIVQDSRALGASLLHERIQTTVQRESQRASEVIEICKRIDQFKQTIDSERDKLEAYWTQYKKVQNDFAKFSAQVIGGDVPGEKEPSEGYHIDMHLLDAEHATEMALLLEEVTKVSHEAIEKMKASEKEIDIKAEKVRQRIKSMPFDQEKQIIHAIKRLLLPCHKMRKRKIDIIWPVGEQSPLYKQFLSRPTNLKSVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KEN1</accession>
    <name>A0A5N6KEN1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KEN1"/>
    <dbReference type="OrthoDB" id="28755at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="74"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="233" mass="26566" checksum="BD1234268ACA5241" modified="2020-04-22" version="1">MPYAVQPVSITDAPGLSRAMMSAWWEDEHWRVLWEKSGTTLEQIISDCTQRQPRSLTKGRNVKRHLKVIDTDSGEIVAYSRYIVPESYVDFWLEAQIPEPSPEEHAEYERRFDEVTDDGMIKGMDHDFASEFGNPLEEVEGSILKDIGPCFAVDYMTTHPAHKGRGVASMMLKEALKRVDEASLTSIVMASPAGKKLYEKHGFKFVRSLVQDDSRYGTTTPYVHSWLIRQPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KEN8</accession>
    <name>A0A5N6KEN8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1748-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005573</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KEN8"/>
    <dbReference type="OrthoDB" id="16824at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013726">
        <property type="entry name" value="Mitofissin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075:SF1">
        <property type="entry name" value="DUF1748-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08520">
        <property type="entry name" value="Mitofissin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="8241" checksum="541292532826F3F4" modified="2020-04-22" version="1">MLGKLTHYAFDAVLLSAFLAGMKRSTGLTPSLKKDLTENKELNGWIEKYLGVGEWVMDQSVAIAGSSSFFERKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGP2</accession>
    <name>A0A5N6KGP2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_006199</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGP2"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070936">
        <property type="term" value="P:protein K48-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15737">
        <property type="entry name" value="FYVE2_Vac1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051878">
        <property type="entry name" value="ZNRF_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46661">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46661:SF4">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="13">
        <location>
            <begin position="269"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="393"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="465"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="546"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="220"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="237"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="403"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="471"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="546"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="594"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8302867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="671" mass="72728" checksum="DFAD8408A69AB20C" modified="2020-04-22" version="1">MDDQWVTSAAGPSSPSSTNVPEGQPLKSPSNFPRSHFYTEGSDSGEDSHMVGFVGPSSSEDNFNSQVMVGPGEDSEAATESQVNSRSNSQTEIEGDISALEVALDDQATVRMSLGSDTSGSSEGSSVSSDEPRQTSSLGKAPIREESSSHSASTAGYQADMSTTLDGVPSLASNSRRNTSSSRFDRRYSYHSLSSRRTSTQSTQSRRTSASQISLAEQPLRSSANPTNSSSDEDGTPTISRSSEGVLQQQARGRETLHGEVIVPRWQPDSEVTQCPICSTSFGWLSRKHHCRKCGRVVCNSCSPHRITIPYQYIVQPPDHPSPYNSTAYNRLHDPQGEGRTNTSEFGGGDRVRLSALSLNLGTTLYIMAGHKVSIVPTTSSPGSLPAESRFRLADHRSHTVREQSSSSRHSGTGTNSNPRTAEEFQSWYRERAALGSGQSTRSRSSTVAVVGRDATEDMRTFLRNFRGPSPSLQNAPDAPTSTAGRRHAVPVEDLRTRPLPRTPQIREEDECPICHRELPSSSLANAETLRSEHIISCIERTTSRISTRTPTSTPAPPIASTTHPVLPVTLPSNQPSSSRASASSTPGLPPLISTLSSGPSQPRRTGVFPYIATEKDCQDDAECQICLEEYEPGLEMGRLECFYVVIEDGFWDDCMTKNHGFESVKVLDMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGQ0</accession>
    <name>A0A5N6KGQ0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGQ0"/>
    <dbReference type="OrthoDB" id="5384020at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="228" mass="24104" checksum="BCBB99F7C0E06EC3" modified="2020-04-22" version="1">MSSNDNNDNTTPPNEGSARPRRGSISAQTFTNIFRSNSTSTGGPVGPFPGSISTAACQDHKRRMSISTLGLSSASPTQSSAFPFGGRRGSVSTASSSIDESAIDDDDGPPMSTPTTPFARRMSFGAQALRTVRAGNGSPVTNGEGGFNWSEQLRSRAESTVSQSQRPSLSTSPPNNSRFHTTTHERAKSIGDVPSPPTAIPPTAAPRPARKQPDAFQERILKGDFYMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGQ2</accession>
    <name>A0A5N6KGQ2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGQ2"/>
    <dbReference type="OrthoDB" id="5353310at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="21703" checksum="CC1EDD1E6B5ABC82" modified="2020-04-22" version="1">MGGKPRNFGMKEHRPSPLKQEVSQRPVSMQSPSIGLVRDPMFWKRFSTAVHMSEVDLKEIESGFASERLENRKDSYGGGEDWLDQQYKEKRRCRLICMVVTFGVAILVAAADGWKNRSRKINPLRNNFLRYVTKFYDNDNGMELYLEWFEIRFDRFDYSNNELNELNGADIYHELRLRKLLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGQ3</accession>
    <name>A0A5N6KGQ3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Poly(A) RNA polymerase mitochondrial-like central palm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006277</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGQ3"/>
    <dbReference type="OrthoDB" id="407432at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050265">
        <property type="term" value="F:RNA uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF40">
        <property type="entry name" value="POLY(A) RNA POLYMERASE GLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="2">
        <location>
            <begin position="77"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="784"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="815"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="921" mass="103740" checksum="CABD14D93B115748" modified="2020-04-22" version="1">MYPQQHQQHPWQNMNQAIPGPGSFNSRPAPQNRQLYQPGLSTPSGQGRRNFGVTSEELASQSAFLDKLAEECVPKVAIDTSEANKKEEFRAHIENICRAAITEHEQEELGNKYFDASTVELKCYGSLSSGFATKGSDMDLAILTPFSNPSAESSESQIPRLLEKRLLGLGYGARLLTRTRVPIIKLCEKPLENLLADLLEERKKWENGLVEGQDDDDADEKHLESQTTKSPEQIPVDVNSKVKSSTKTTSNISKPTNKGEVQPVEKKAVSLKQKEHQNLVDYHICAKRALRKHGGRDLSLNSTDLNMEEAKLLNEVCRAFILGLYSEDLSNRLSNYPSISPLFDPSVPCVQRSLNGICTQVEGERLAMAWEKRLIFEATDKQESDALAVLEAWRALQNKTGPITESEIYNRQLHTASERLKKINSLQFLCLEQLMFESPKQYLAKVEKLKGDLEGKGVPQHLIRLRQLNDEEVDAQFLKRYIDGIHDSQIREAMQCMEGIATLNDAAHRHQILQLAKDYEHALEASLYDENSRPHVERYIPILRDIASGQASVDSSQAELVAVMRTLPDPTQISLNKPRDRYKDHLEFPKDKVGIQCDINFSNHLALHNTLLLRLYSVCDPRVKVMVLFVKHWAKTRGINTPYRGTLGSYGYVLMVLHYLMNIAQPPVLPNLQHMNKEPPAHLSPSEKAAQTSCDGQDVRFWRNEAEIRSLAERKMLTHNHDSVGMLLRGFFEYFAQSAQMTTVHGVRGFEWGREVLSLRSKYGILSKQEKGWVGARTVVETTQIAAPTPTTPKLSTPAISKPSGENAGNSSSEPELKLEKQPPRTMKETKEVRHRYLLAIEDPFEIEHNIARTVTHNGIVSIRDEFRRAWGIIKSLGTRYQSKDGLLDSIPKPGDSKVELQILLDTIHGLEKDGVAVGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGQ4</accession>
    <name>A0A5N6KGQ4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Domain of unknown function at the cortex 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGQ4"/>
    <dbReference type="OrthoDB" id="2119945at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013897">
        <property type="entry name" value="Duc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34826">
        <property type="entry name" value="UPF0590 PROTEIN C409.17C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34826:SF2">
        <property type="entry name" value="UPF0590 PROTEIN C409.17C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08588">
        <property type="entry name" value="Duc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Domain of unknown function at the cortex 1" evidence="2">
        <location>
            <begin position="7"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="349" mass="38930" checksum="9C578DFCC99E9EF3" modified="2020-04-22" version="1">MAENYILQVTAGSGYDITQHQIVPVNQARCVRIDNELCEVELNVRIQDYRGLPTSSPATSPYFDLPPHDRNKDQYSIGFRFRPKRDVNADDLVFGNDFDHPIRDRLPPGFNAAFRIVKWMVDPGLDGDVYADEPYLYGPAASSFNVLYVGEGGEGREEEGEGEEEGGAGLVFEEGGDEEGEDHRRECGIPDGEAARRKYFLTEANRREWDWEEGRSYGCDFFNAYLDFNSFAVKLPGYSMPIMKYWDGQGLRYVLKNRKTGEVLFVVLFTLYLKEDVDENGKLKDGVEGGKPFDLLPKEVAERHLREKDGDGDGNEKREEKVKKSTDGGDGGGDGGDGGDGGDGGDDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGQ9</accession>
    <name>A0A5N6KGQ9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGQ9"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="528" mass="59163" checksum="969225152B3B0CD7" modified="2020-04-22" version="1">MRCPSCGHEHEGGPTCESCGAEFDDVYGFSDMSDDDDISDLDVGYDDDLQEELEAEMQMGGGGMNGFEYHPGGPFMGGPHHQFLRHYHTHNHGFNLDDATDDSENTSYQGNSEDEDAGSLEDFIAPEDDDSEPVAAPRRANQRVVTIISDDEDDENEYEEGEEEEDEDEDEDDDDDESEEDEGGAVTNRRRPRPGWTRTSNTPSISALNTEDDNGSSTNGSEFGDDDSHETRMRLRASGGWSPLDEGEDDDDEGLVHDHYTGYATTEDERATDESDSETIGNPNSDAEDDDERGGYSESRHYETGNFQQTLDDYPSSMEGDSTPVDYSRERYGESVDFNSEHGDSYDYDTDGGQSTNMDRDGDTEMSSPGLPRSSRSVSVNSTYENLGVANEMAEIDDDSSDTSIRPPPRRQPRQNPYVQQYDPRISMLFAEHQNSVRNAQNPGLDAWGDDIRNNIRVEAGSRSRRRAQYHHQIPSHGNSDTRNNHHRIIPPRGFHRARTPRGSPPPRIVPVSSRASRLQRHYPRDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGR0</accession>
    <name>A0A5N6KGR0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_006282</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGR0"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF15">
        <property type="entry name" value="ALPHA-FACTOR-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="67"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8302970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="535" mass="59262" checksum="346DBD31426CAB4C" modified="2020-04-22" version="1">MTILKGKGSKSHRWHGHPNSSIRLAVDDQESSIELRNVDNYQSDDEIKSSFRSLFAFTTKEHTLNLVLCIIFAIVSGVLKPISAIFYGNIFGSLTNYGGGVITAQETLHRVSKWCIAISVLGGAVWLFEGLFLCSWVIFGELQARSVREKMFVGMLEKDLEWFDLRKDGIGSLLIRIETQIRELQLSTSQPLGFLFFETAGATAALGTAFFYSWSLTLVIIAAFPIAGGILYLISKKMGPAIEAQKRELSQASKLTNTAITAIDTVKAFNGEDQEVWQYFLAIKRSTVYYMIQARSNAFQFGITKFVIIAIFVQGFWYGISLVDHGLDAGEVLTTFYACLSGMVAIEVILPQWLVLAKGMSAGATLKFIMDQVDRGGITKRKEESITPQSCVGDIEVNDVTFAYPSNRQQNALTKTTFFFPAGETTFIVGKSGSGKSTLGNLLLKFYEPQEGNILIDGQQIQDLGTDWLRHKITLVLQQSVIFNETVRKNVEFGKEGETNEADITNACSAASLEQVIADLPNGLDTMIDYEMRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGR3</accession>
    <name>A0A5N6KGR3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_006198</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGR3"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000003">
        <property type="entry name" value="C6 transcription factor (Leu3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF39">
        <property type="entry name" value="TRANSCRIPTION FACTOR PBCR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="110"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8302865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="189" mass="20911" checksum="43BDB4C56CEFAC7B" modified="2020-04-22" version="1">MENNVNLGQIDPRLRDESNTNSFAHSQQQQQPQSHPEIHDLNTQIPVSGPRLSAPSPTQLAQLQQYHQPIHDGNQPQVYLPHTPQSAGNTPDDGGTMFGESSTDAKRPRACEACRGLKVKCEPDMNNFDGPCKRCAKASRHCVVTVPSRKRQKKADSRVAELEKKIDALTATLQATKPWPTQSNKTKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KH12</accession>
    <name>A0A5N6KH12_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KH12"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="85" mass="9684" checksum="F76F78FB9CA8C8B8" modified="2020-04-22" version="1">MQSSKIAELRFAEFPNGWSSMLGLLSDFLSSHIYYWAAISRHGIEAFASIGLHNVDHFSKTSVHKRSPPTHACHTRSHANRKYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KH25</accession>
    <name>A0A5N6KH25_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8303002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KH25"/>
    <dbReference type="OrthoDB" id="10261782at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038921">
        <property type="entry name" value="YOR389W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204:SF1">
        <property type="entry name" value="ENTEROTOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204">
        <property type="entry name" value="YALI0A21131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="383" mass="43511" checksum="A7C53DF7659C76D2" modified="2020-04-22" version="1">MRVLDDEDSRATALNALMRRRRSYTLDDVSTDEAAIMKEDSERVLETLMGQPVNCSDIDWTAMTNEIVRTYASPLAQLLHSLRNYSSIPPSNRSAQRKWLSSIRDQTHSLLLPFLEYPSPEENPSIWTRQSPLFQTTHSNCHHHHTRLLSSPNIPLFPEERTLESAIEETQGQICNIIISIGFSIENIWNSSFNQPSTNSNDNPASPLEKNTKEFTRWIHGIEELMAWLGWACEWTSWGEGPARRPPPRYGYGPGKEHGPGYRHGSGYGYGGPPGRGDHNPPAGGDHPGRPSWRIDETDLWQPRCVGLEYIMGCSHIMSSREVPKLLDDQKGLEVRQLREAWVLYGIGIDDLVDIHRFSDLKGDVIVPVPRQEHKTIRSMTQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KH34</accession>
    <name>A0A5N6KH34_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">EYC80_005937</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10266508at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071474">
        <property type="term" value="P:cellular hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06225">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000001">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000015">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000207">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1530">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18947">
        <property type="entry name" value="HAMP_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HAMP" evidence="15">
        <location>
            <begin position="197"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="15">
        <location>
            <begin position="292"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="15">
        <location>
            <begin position="384"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="15">
        <location>
            <begin position="476"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="15">
        <location>
            <begin position="568"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="15">
        <location>
            <begin position="660"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="13">
        <location>
            <begin position="734"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="1109"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1240"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="135"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1243"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1281"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="1158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAB8302549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1316" mass="143791" checksum="39A3F95F7DB652F9" modified="2020-04-22" version="1">MGDSTLAATTAILQSLALSSIDLPQSNVYGNKGIRLPGADTAGKLTLERELAALVSRVQRLEAKAITVNNQALPDTPNEIGAPSAFADVLTGAPSRASKSTASRQQLVNSLLAAREAPTGGERPPKFTKLSDEELEALREHVDDQSKQLDSQKSELAGVHAQLFEQKQRQEQALNVLEVERVAALERELKKHQQANEAFQKALREIGEIVTAVARGDLSKKVQIHSVEMDPEITTFKRVINTMMDQLQIFSSEVSRVAREVGTEGILGGQAKISGVDGTWKELTDNVNVMAQNLTDQVREIASVTTAVAHGDLTQKIERPAQGEILQLQQTINTMVDQLRTFAAEVTRVARDVGTEGILGGQAEIEGVQGMWNTLIVNVNAMANNLTTQVRDIAIVTTAVAKGDLTQKVQAECKGEIKQLKETINSMVDQLQQFAREVTKIAREVGTEGRLGGQATVHDVEGTWRDLTENVNGMAMNLTTQVREIAKVTTAVARGDLTKKIEVEVQGEIASLKDTINTMVDRLGTFAFEVSKVAREVGTDGTLGGQAQVDNVEGKWKDLTENVNTMARNLTTQVRGISTVTQAIANGDMSQKIEVAAAGEILILKETINNMVDRLSIFSNEVQRVAKDVGVDGKMGGQADVAGIGGRWKEITTDVNTMANNLTTQVRAFGDITNAATDGDFTKLITVEASGEMDELKRKINQMVYNLRDSIQRNTLAREAAEFANRTKSEFLANMSHEIRTPMNGIIGMTQLTLDTDLTQYQREMLNIVHNLANSLLTIIDDILDLSKIEANRMIMEEIPYTLRGTVFNALKTLAVKANEKFLDLTYRVDSSVPDHVVGDSFRLRQIILNLVGNAIKFTEHGEVSLTIQKAEQGHCAPNEYAVEFCVSDTGIGIQADKLNLIFDTFQQADGSMTRKFGGTGLGLSISKRLVNLMRGDVWVKSQYGKGSSFYFTCTVRLATSDISFIQKQLKPYQGHNVLFIDKGQTGHGKEIITMLTQLGLVPVVVDSEQHTILLGNGRTKEKIASTYDVIVVDSIESARKLRSIDEFKYIPIVLLAPVVHVSLKSALDLGITSYMTTPCLTIDLGNGMIPALENRAAPSLADNTKSFDILLAEDNIVNQRLAVKILEKYHHVVTVVGNGQEALDAIKEKRYDVILMDVQMPIMGGFEATAKIREYERSLGTQRTPIIALTAHAMLGDREKCIQAQMDEYLSKPLKQNHLIQTILKCATLGGALLEKGREVRQSANEESPNSQNGTRGNIQHPASSPTPAHMRPAIEPRAYTTTGPINHGSVESPSLVTADAEDPLARLLMRAHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KH40</accession>
    <name>A0A5N6KH40_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SprT-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004552</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KH40"/>
    <dbReference type="OrthoDB" id="3541176at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="21179" checksum="1F27778A31D77FDB" modified="2020-04-22" version="1">MIKDSIVADFAINEWKNIFKLELVSNDARAEEVNLGDNLGITSHVDSGYFRTTTIYIRDIRTGDINEVFTKVVIEMLGTLAHEMIHAMESMYHMYTADEENVDRAWHCTPWQEVARAIERATSGSPVGHNWLGMKLDLGREESAVSDVVLRGYKEPTALELHAMEFDVEKFRRHVDRWFDSIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KH41</accession>
    <name>A0A5N6KH41_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCZ1/INTU/HSP4 first Longin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_004554</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCZ1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KH41"/>
    <dbReference type="OrthoDB" id="240546at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035658">
        <property type="term" value="C:Mon1-Ccz1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013176">
        <property type="entry name" value="Ccz1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043987">
        <property type="entry name" value="CCZ1/INTU/HSP4_longin_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13056">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13056:SF0">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19031">
        <property type="entry name" value="Intu_longin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCZ1/INTU/HSP4 first Longin" evidence="3">
        <location>
            <begin position="15"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="265"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="331"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="454"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="548"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="396"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="548"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="573"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8303103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="742" mass="82130" checksum="316E5DCC78224E2C" modified="2020-04-22" version="1">MSDQRRKVVPAQLGFLAIYNPSLGTTDDTLENQIVYYYPSAKQNAHKRKGSNDTKDARAFAKEQKNEQLRQIGLAQGMVEFGRSFSEGESVDTIETEKSRIILHELESGWWILASINLTILPGTTKTPATKGKPAEEQETIEYSSREVKPAILLLGDILRAHSTFLLHHASSMSALFVRTRRSKFVGILGRYWDTYLSTWNVLMHGNPANNLYGGIKVAACGELGVGVGEEDRGSGEREVLEGFVGQMEGLVDVIVSRFGDAKSNVDDSSKGLSEQHSKQAAPWLGSGNEPATEDGAIFLGTGALSRKSLRDVSHWVEDLYKWGQYAYGVVDNPSSTRRAKKMNKPRPRNDQKLGNAKNAARPMSSLSNEIPIHDGPRDQPGPSRQSSISTAEPRPTVEEDSHSDRPKSQSKPPRPVFDRNHASHTSTEGTDGTDGESKGSKFAQYLKLGYGTHWSLGGTTTKEDESKSSSGLATPISSIDGAAETTGRSSHIPEFDDSKGHYLVGLMGDIEAEIHTPVIPYADDDEFEGQNSRLVLRTLTVELEREEDARQEADISIDHSDVGPLFRHNSGSERTGNSRGSFESQDRNKTKKLRVVVYANQPFIFIFLFELRADSLALEHLYQSLHKQLQSLIKPLLKSTSFRAPKPEIPISPSANTNNPTAPIYDLLWDPKSLTLNSNIPNIPDPQQVQTQEQADRLPWSRIEALNTHLQMLHTYIATTTDKNTLERTAKTSRGKSKFQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIT3</accession>
    <name>A0A5N6KIT3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIT3"/>
    <dbReference type="OrthoDB" id="88410at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="90" mass="10182" checksum="C94BC81D5BD0043B" modified="2020-04-22" version="1">MSNMSNMYPMSFHLTLKKFYLRRISAKSVKPLVFEIIPQCVDRQAVPPARRKPGLAVECTYQYPPKVGTGKAQDSGEEGDVVIHDLKRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIT4</accession>
    <name>A0A5N6KIT4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane iron permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_005080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIT4"/>
    <dbReference type="OrthoDB" id="4364at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="IRON TRANSPORTER FTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632:SF2">
        <property type="entry name" value="PLASMA MEMBRANE IRON PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8303693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="22765" checksum="5D5138543EF8DE4D" modified="2020-04-22" version="1">MTVNVFSVPVFFVVFRESLETVVIVSVLLAFIKQSLGDSDKDATLRKMLFRQVIWGALSGLLVCLVIGGGLIGAFYGIGKDAWANAEYYWEGSFAIVASVIITLMGAALLRVSKMKEKWTVKLRQNLEPSEDTRTRRWYSSWLDFKSWGEKHFMFVLPFITVLREGLEAVVFVAGVSFSTPPTSIPLPVVIGLIAGLAVGYVIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIU2</accession>
    <name>A0A5N6KIU2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Citrate/oxoglutarate carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_005085</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIU2"/>
    <dbReference type="OrthoDB" id="10253709at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005371">
        <property type="term" value="F:tricarboxylate secondary active transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015742">
        <property type="term" value="P:alpha-ketoglutarate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006843">
        <property type="term" value="P:mitochondrial citrate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000053">
        <property type="entry name" value="Mitochondrial DNA replication protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000085">
        <property type="entry name" value="Tricarboxylate carrier, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053017">
        <property type="entry name" value="Mito_Cit/Oxoglu_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46982">
        <property type="entry name" value="CITRATE/OXOGLUTARATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46982:SF1">
        <property type="entry name" value="CITRATE_OXOGLUTARATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="225"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="330"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8303700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="44077" checksum="F0EECF20DEF9AFAF" modified="2020-04-22" version="1">MDRIEASSTSATWVRISIYRKVSGWSTILPHPVSFGLGLLQYSNLPIFATSAFPLPPSICSLNIHPSVNLSLLSSHFLFNNKTSISPPFRREEATYSLGQGPNQNTTCLIMSTVTANAPLVGKPAVPEKKPVKFSNLLLGASLNLFEVTTLGQPLEVTKTTMAANRGDSFAGALGRIWGRGGVYGFYQGLIPWAWIEASTKGAVLLFVASEAEWHARSFGAGEFTAGITGGVTGGVAQAYATMGFCTCMKTVEITKTNMAKAGVKPDGTMTTFMNIYRKEGIKGINKGVNAVAIRQMTNWGSRFGLSRLAESGIRKVTGKGEHGKLNAWEKILASALGGGLSAWNQPIEVIRVEMQSKTVDPNRPAKMTVGNTFKYIYGQNGFSGLYRGVVPRIGLGVWQTICMVAMGDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIU9</accession>
    <name>A0A5N6KIU9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ER membrane protein complex subunit 7 beta-sandwich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_005091</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIU9"/>
    <dbReference type="OrthoDB" id="27095at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019008">
        <property type="entry name" value="Beta_sandwich_EMC7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039163">
        <property type="entry name" value="EMC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605:SF4">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09430">
        <property type="entry name" value="EMC7_beta-sandw"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024884826" description="ER membrane protein complex subunit 7 beta-sandwich domain-containing protein" evidence="7">
        <location>
            <begin position="21"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 7 beta-sandwich" evidence="8">
        <location>
            <begin position="34"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8303706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="204" mass="22471" checksum="2DDBCD25ABB1346D" modified="2020-04-22" version="1">MRFSTISALSLLSLLPSALATHLLLTIPTTPQLNPATLLPSTHATLSTLSHTHTAPLTSSNSFSFRNLTSGSYLLTISSQTHAFIPLRIDIHPASSEPNLIPVEAFTTFRSNEWSNKGEVVPVSKLGNGKYTAEVKVLVEKNYYLERVGFSPLSLLKNPMILIAGFSMVIVFGMPYLMDNSMYILLLFNIRPAALWAQFVQSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIV3</accession>
    <name>A0A5N6KIV3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3'-5' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004617</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3437384at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040:SF1">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="2">
        <location>
            <begin position="99"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="682"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="985"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1210"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1377"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1526"/>
            <end position="1654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1812"/>
            <end position="1874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="688"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1255"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1394"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1543"/>
            <end position="1552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1589"/>
            <end position="1598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1826"/>
            <end position="1840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1864"/>
            <end position="1874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8303169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1874" mass="207338" checksum="34E57BA8F23172D1" modified="2020-04-22" version="1">MFDRLLVASSYQSLPFLLNLQQSHLYNQLQYNFRPTANTTPGPSSLPSRIMESIDALARGIKKTVVGTDPAINLTDTPAGIIKLIDSLARSDLPTSPPSVYIDLEGVNIGREGSISILQVFILPIDEVFLVDVYNLGEQAFSTENTSGITLKSILESQLIPKVIFDVRSDSDALFSHFGVKLSGVIDLQLMELATRSRGRNFVCGLAKCMDRDLVQTPEELKVRSAIKKRGKELFVPELGGRYEVFNDRPLDPAILNYCVQDVRLMPELWETYNAKLGQVHKVWASKIERETKARILLSQSPGYNGTDAVSPRPMKSPSVTPANTLRKSPRKASNLRIEELQAQVSSWSSSTKTEDGTEIRAIFEGQCFSPSDKENEIVAANEQDSNEEDEDERHQEVKPMLSSNTLKSVKSRLKKTFSRESGITKKNDKRRSVGTSEEEVERRKELRRLRQKRIEEELSYDHEYDEDAQSMSTVDCPTTRNIGKGKKRQSILPEDSGNFPVFRKQSSSFGSEEILNGSRISLCTNNVDNTSKVSLSKKIDDTSKLSLLTPDNRVKSRTHLGTTEPNIHLLRPNNTPPRRYSSPGPFPTPSEITSLQPELFRSRKTESEGFPVLSAPITEARRLPSSTTHRESASGWRLSYTSHKSNRGVHLRKLSQQFEVPVQSATGFANVGTQTLPRWLQKQGTGSSSRAITTSESSTVNKEPLPMRPPRSDTGFGGVDGSGSFSAVHLQDMGISKHLLQSSCSSPQLVNWEKHDREVSNISNLVQSRARYMRNPSDSVSIPSCPSMALSELAPPNLGRMPYDSTSSFYPSIANSIQASPECSRLELLSSGSTSKSILAKAESQAIDQILTPLRSPVIPTTTGANTPATINLSLTSFNLNAPLSRYSARQIDESSLFASETTSFRERELELSHIQTRFASSNLSRPPSTPISSKFREEFDISLTPQPKSPFQKLVRACSLKRSRDNTEDELLLAPPHRSGFGYRFSSTPSSLGRTSSTRNPTPTKPFTGRKRTPTTYDLVDTPVKSKFSAFRRIKRLASLGGYDGSADDHRRSVVDSGTARRPSALDARLGLGADMTASEAQRKVSMPFIRLPTIQPSHDASIIGGPDLDVPRPLARIGTSMHIDLPEISLPRIGNPLHINTPNIHITEMDVPNPMAHIGASMHIDFPAPHAPDAAASLFHTPHLEMPTPHLPHIPRLSIGHHDEYSAPKEKKAPKAAPSIVPIAPPKSKVQLGKAPDAEVPQWRGPRARNRSSREDNKRRMDTTQDDSAAVWMKAVKGAVNDRSKARKDNQDGEDIFGDWEAQLAGVALKSKYESRKFGSRGKPKIHQIEQFPPAWCRFPSHERNARGHESAGVEAAVEAKDFAALRAGTEVLGRPEHSFGARRRRRPGMDTSNSSDPSSTHALSDDELNAIEAAEPWLKRWSNKIKIAWMDYRIEEGQRKHAFNSGSLGRRGSMTMDGKVPFPELELLPMRAPPPPSEVVDDEADDLEAERKRVEEIRKAKIKPHYVAADLTESKGGVGDLLDIFSTGPEEPAEPSMPIKKKGPRAKKAKDPYALDDDDDLGGGGSKGDEDEMPKKKGKVKDPYAIDEDDDEDLPPVPKKKKKANDPYSIGEEDEDIPPISKKKGKAKDPYSIDDDRDGSSDFGSGNELGKIDEVASKEVLSDDDTIDHTRFEDSIISFRDPEFYQDCLVMPKEPSPVHIKECSVVSSHGIIEEEIKDTSGNASGIIVQVQEIGEGVVKQIEKFRTWNGRDWEREMGAFLKRRDTSVGRDSMRSARSVWSTGSQGTVRSVGVEVRRLEDLERERGKLRSVGGHLTGGVPRRARGERGRDRAMERERRGHGRSVSLGVEGLGSTDSGAGEVRGRRLTFGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIW2</accession>
    <name>A0A5N6KIW2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PUM-HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_005103</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIW2"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010608">
        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000237">
        <property type="entry name" value="Pumilio homolog 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF13">
        <property type="entry name" value="PUMILIO HOMOLOGY DOMAIN FAMILY MEMBER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="5">
        <location>
            <begin position="155"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="181"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="217"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="253"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="290"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="326"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="362"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="398"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="434"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="72"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="493"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="74"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="493"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8303720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="599" mass="66289" checksum="3D2E562D1BC8561C" modified="2020-04-22" version="1">MPTNNTTPISHAQQHLHNHNASLGRIPPNAMNRLSREMTSGDNGTLREAQNGGYQSIQSALQASAAPFGPALTQGMSQGLSQNMSQAQMSPSVTSPTGQQNYPGSVPGYYNNYNMHMMSLGMQNMQLGQPMYPPPNPYNNYGNSMYQHNGGQRDSQARVIQQRRQNDGEAMNRFANVALEQLGGEIYALCKDQHGCRYLQKKLEDRNPEQVHMIWLETNQHVIELMTDPFGNYLCQKLLEYCNDEERTVLIENASHDLVRIALNQHGTRALQKMIEFISTPGQIQTIIGALRFRVVELIQDLNGNHVIQKCLNKLSPADAQFIFDAVGQHCVDVGTHRHGCCVLQRCIDHASGDQKAWLIRQISNNAFVLVQDPFGNYVVQYILDLNEPIFTEPLVAMFAGRVPQLSKQKFSSNVIEKCLRCAQEPSKDMLIEEMLQPNQLDSLLRDSFANYVIQTALDYANPSMKTRLIEAIRPHLPAIRTTPYGRRIQAKIQGNENRGNTSTGPTTPNDNESGQLATRHQRGMSNVSAGPFVSSPGGFPNGIGPAPLTNGLTLPAIRSPTQQGAGFPPNDRLTSPAAAHPYNYGRTGTQPGAGSDWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJ61</accession>
    <name>A0A5N6KJ61_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_005205</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJ61"/>
    <dbReference type="OrthoDB" id="366230at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010970">
        <property type="term" value="P:transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF22">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="22"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="144"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="94"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8303833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="404" mass="44706" checksum="97D98E5B6880665A" modified="2020-04-22" version="1">MQQRRDEILAKKAKLAELKRQRELRAREVSASRQSVGSGSDLASPTPGRADNRRELDSLISSLVGDSRPASTGPGGAGSPARGSRPNSVLSAGELSNAPSESSPSNAQVSQTQPLSISTPQALSTVPLSTVYEFTPSPVKEVFSYSKGVQTTEEWGTQTSRPRAFDDSDDEIDRSSGVQSPSKRLSRREKNREEELRENIRREIEEELKATRELVDGPIRPDSQHSPTANFPARILTNEELNAVTSSEDFMDFVERSSKVIERALDQEYDVLADYGLSGANGVGDDDEYGNTGGKGRRKIKEVAQFYDERWSKKRMISAIDFSPKFPELVLAAYTKNPSAPHDPDGLVQVWNMHLHDRPEFVFHAQSDVLAAKFSPFHPNLIIGGAYSENTFDWLRAYPSSLFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKY2</accession>
    <name>A0A5N6KKY2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKY2"/>
    <dbReference type="OrthoDB" id="5389734at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8304362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="86" mass="10104" checksum="DCA2F3A1BB7F49AF" modified="2020-04-22" version="1">MAFYDSSSDQEVGFPIILEPDDDDSLFEMRVDDTRMNNDTMKEVHQVREVKKAEEVNKNTMSQWKRLATQVEQHQKLATQLLDDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKY9</accession>
    <name>A0A5N6KKY9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_003765</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKY9"/>
    <dbReference type="OrthoDB" id="413885at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.10">
        <property type="entry name" value="Cholesterol Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053208">
        <property type="entry name" value="GMC_Oxidoreductase_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190:SF4">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="225"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="500"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="500"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="545"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8304355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="560" mass="58588" checksum="6057C4B4D13CB0AA" modified="2020-04-22" version="1">MLERGNVSTYATGGRSTVGWNNTVTQYDVPSLSYYLTTASATDEYCTDTASMAGCILGGGTMVNALMFVRPQEVDFDDKWPTGWKWTDVSASADRLYERNPGTTNPTSNSERYDQGAWNALSSFLGGLGWSEVDAIKSPNEKTQVYSHPPWDIQDGLRAGPVKSYYPLATAMSNFKAQFNTKVVRGIRSTTNSTTFSGVEVENVSTGVRQIINLKAGGKLVLAGGAMSTPRILINSGIGPTDQISIVQNGSSCVTLPAQSDWINLPVGKNLKDHPIFTLTFNVSASMASNSTSLLASAFTSPNITNIDLFAQQTGPLAQSGQRLSFWTSLNTTSGTKYFQGTSNSPAEGQIRIKIYLTHGLTSTGVLGITGTGATEFTTNPWMNTDDDKSAVETVLDYFINAAKNSTILTPTDSTVTGASLVAGNKYVTGSHFTGTAIMGTANDGSSVVDTDTKVWGTDNLFVVDASIHPDMPTGNTQAIVMVAAEQAAQKILALSGKTISSSNTSTSTSSSSSSGSGSAASGSAVSGATTSASSAAASSGSGESGDDDDTCPFGYELEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKZ6</accession>
    <name>A0A5N6KKZ6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TEA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_003839</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKZ6"/>
    <dbReference type="OrthoDB" id="10006572at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.40">
        <property type="entry name" value="TEA/ATTS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000818">
        <property type="entry name" value="TEA/ATTS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038096">
        <property type="entry name" value="TEA/ATTS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050937">
        <property type="entry name" value="TEC1_TEAD_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11834:SF0">
        <property type="entry name" value="PROTEIN SCALLOPED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11834">
        <property type="entry name" value="TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01285">
        <property type="entry name" value="TEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00426">
        <property type="entry name" value="TEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51088">
        <property type="entry name" value="TEA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TEA" evidence="8">
        <location>
            <begin position="123"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="TEA" evidence="6">
        <location>
            <begin position="123"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="46"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="679"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="688"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8304444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="734" mass="83312" checksum="DC506C68F4906D8D" modified="2020-04-22" version="1">MEEPRNILPSGYSSQQLQLDESSGLSRLKEPLSDSAGNAQLHELASANIYHDNKRHPMRGQERSMYSMPTLPSQPLRQPVGNTLELRKRHNRQQRFNRHNNRNPIVDSPQYQAYRARVNRDGNPVSDSKWPEELENAFLDALLAIPYMGRRKFSFRGKPHGRNELIKEYLWIAYKNTLPSGQRPDPTMMRTRKQVSSHIQVLKGFLTPHPALYQRLFPPNKGPKNGFEDSFKKDPTLIALSQGRLPSRRHDQYDGLDQIILSNHHPMKPAAFWLLMTPFAVPNERNGVMRTEQDLRRDGLVLHRYSGLSSPKPRGSLESILHWRQKFPHLAQSHSTNDLNCDIIHMDVSLDLMKTHAPDNSELLTRLEMSIPSREFAGFDWQSVTSLIKPAELYGDPTRDPVLEGTPLPMTVLGRTDSETRIKVAIPAETWAYTFTQLMNLHFELEKKRLPQAYGGDGLGRSINSVRGYVDQISMYQELQSSAGERMPFIRRAILIWTFHKARSGEGSDTTWRYVDPAPPRHMCMSPPPHPNNHILTNLEPYNSWPESPLHMQQPNILDSFVQGLATPPHTAGLQSPFDTTGYTYSAQHFDMSNENISFVSHATVDSESTLVNEADPTNNIDSFLSNSAGVNMGGYGDVSGHYYGHLPSNSVNANESFDADPAWENYSVPVSTPWEHSEENKGLAWPDTSTQIEPSNKHAWSNDTQEQNKAQEVWNADDINVNGVHVNERDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JQD2</accession>
    <name>A0A5N6JQD2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_011019</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000018">
        <property type="protein sequence ID" value="KAB8290150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JQD2"/>
    <dbReference type="OrthoDB" id="5305647at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059009">
        <property type="entry name" value="Znf_C2H2_17_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059095">
        <property type="entry name" value="Znf_C2H2_17_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF24">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26177">
        <property type="entry name" value="zf_C2H2_17_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26176">
        <property type="entry name" value="zf_C2H2_17_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="622"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="289"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="470"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="671"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="472"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8290150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="741" mass="84558" checksum="94C3905C027B14D7" modified="2020-04-22" version="1">MGFRGNRQKTIKGLCYDMSNGLGSLMPQHAGNSLIFIALCLCYFFLIALIIRLKPMEPSHTLLHTSRQPKFRPEIGTGRHARLFGVGWFLEWPGGQRPLNSTWPWSGVKLSVLVLWGVCWMFYMRIECWQQAQPYASHNHSLPQLLSRKAPGPLSFHSCARAKNYLPLDQQTVIKQEPYDNNLFVSSFDQYHSNHIQDSHLHPQRPSDSNWPSIFNPYLNNTSTSPSTSTRTWTRINNRNNHNNNIVNQETFQPIQKSHQLQYTTTREYIQAAAPSTKQMLLAMPHNLTSNSQDISSKSPALSQGSYRNKGITDDLDNINSTSHANRLLPGVSNLQPSITSVGSPDQAERREYKNHKNQNGGGTQDDDDVLLLSVAGTNTSPHFSAQGKHHFEAGPQSQGYQQLHYQESNNQLQSDQAGLYERGEQIPYEYPPGSNIFQNYDPPRPNNNMSLSYESRAFMPDTQYPMQMAHETQEQDEFKPHDEPHYPSPPPPMSENPYTAQPMTETPEHQVLELPELPKDEEEAPSPGRSKPVPKPDREVTKDANGRFYCTWPGCTEEIKDFNRKCEWSKHMDKHDRPYRCKETGCEKLPGFTYSGGLLRHEREVHGKHGGPKKQLNCPHPNCKRHTGKGFSRQENLNEHLRRVHTDGVMSQMTMEETEEDASQAVITGIKRKRGNSKEDTNELETLREEIKKIKAENDELKRNSQAQQAQTAEVMRQLVELQNLATLQHPRMNAPQANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSF3</accession>
    <name>A0A5N6JSF3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal eL28/Mak16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_006594</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSF3"/>
    <dbReference type="OrthoDB" id="338850at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002672">
        <property type="entry name" value="Ribosomal_eL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10544">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="5">
        <location>
            <begin position="22"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8291803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="125" mass="13322" checksum="4ABB97C01A54E53A" modified="2020-04-22" version="1">MSQYVSADFIWEVTRSQNAFLYAGFVNDKAVGVVPAEKGVTLITKKTSASQKPAVALNKTTFSKSGRKTFAGVAKTVAKNGYRSDLRAEAVARSSAILQSQTPKKDAPAPKLRGSKAAKAAEKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSG5</accession>
    <name>A0A5N6JSG5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MalT-like TPR region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_010938</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000017">
        <property type="protein sequence ID" value="KAB8290509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSG5"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8290509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="68" mass="7664" checksum="A6FBFFC64E40C890" modified="2020-04-22" version="1">MTEFNNQANQLGQAGNQAGAIELHLKALKLKISSMGKLEDARKMFEDADRVRSHLTLDRFDSACTRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSG7</accession>
    <name>A0A5N6JSG7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2423 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSG7"/>
    <dbReference type="OrthoDB" id="4087970at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019434">
        <property type="entry name" value="DUF2423"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28219">
        <property type="entry name" value="UPF0642 PROTEIN YBL028C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28219:SF1">
        <property type="entry name" value="UPF0642 PROTEIN YBL028C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10338">
        <property type="entry name" value="YBL028C_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2423" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8291823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="135" mass="14479" checksum="20784630F19F19C7" modified="2020-04-22" version="1">MAKGARSSSTKANNAALKNKVFGPVENARAERMHAKLLELISQPKPSAKTEDVDMEAKEGKDGEDASSKDSLANATSTTQDKPSEAMEVDAVSKVGSKSKNRISKRRVSSRKSSMTFVTYKKGKKVGGGGKQKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSH6</accession>
    <name>A0A5N6JSH6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_010946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000017">
        <property type="protein sequence ID" value="KAB8290519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSH6"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8290519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="72" mass="8849" checksum="FE2FE2FF0E82D0A2" modified="2020-04-22" version="1">MMKLGGWFKEKERKKERKNERTKGRKDERTKGRKEERHKEQSKDQSIPTYKRKLSFCPEYLVNLKRLVLIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSH9</accession>
    <name>A0A5N6JSH9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSH9"/>
    <dbReference type="OrthoDB" id="3550918at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="593"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="534"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8291838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="652" mass="71577" checksum="41B2988439304D73" modified="2020-04-22" version="1">MELDPVDEFDESKPFYQQVLLIDTTIKDIQSVRIRHDTIGDNVDVFRGFRTIPYSGDAHQHVYPNGEVYDQVPSFYASVANTASMYSTSNKSDIIGEAHPGLSSDTRFGVLVPNQNQPQGRGGSTYQRHDRPDRQHGRGNYQGDRGGYAQHLNRRGRRDMQFGRGQGRIGNGRGDSRAGGHHFEGHNQYNGHREGQNGYFNPQEPAHGIVHHLDELSLDQHREGGYGIEQNRDDFALARHRDNLAMSQHRANLARRYDAISDDGVRTWGERYAEAPIFNAQHAPATGGVFYSAENIRRYGEPPFQEPPVYDGFNEENPYIPPPHLWDFTPGTTAWQERLQVLPGDLNPSGLHTYMAPGIANNVPQYSWPYMHGPARENNAGDPPPYFVPGPLEHMMVNHVDGHHSQCPLSGHDAGVMDAIGPDHGRMITGPRPRVVLPPGTPGERTLETDFGEGQGFLHGNLQSQTPLGPSPGRSPARTTTDEGSPLVRPRRIATDPSNQRTPIGHGHGRGNSGSDLRRWATAHSGFAIAQPRSSPSTGAFSPGPGSPGHGHITSTTARSSPGITFANSGPFGRSIARTASSHELNYVDFSINGETPGQVSRTPTPPINSGRRCFETRQYVPDGSRMSSPGQGSPVYHNGVFTEHRSEDGQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSN4</accession>
    <name>A0A5N6JSN4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_007828</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSN4"/>
    <dbReference type="OrthoDB" id="2590011at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="4">
        <location>
            <begin position="190"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="164"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="263"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8292083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="492" mass="54804" checksum="8D81BC9C641201A0" modified="2020-04-22" version="1">MYVLAKTLLEPWEYEKLERSSVQLSSTIIVLLDKLISLYRFSTTSIFSHAGLQQCSIGKTALENQTIHFWKPSIALEKKKSVTSPEIHCHHRKVRSKNTIPTISWYILSCSSHSSASYATMASLSPDNYDYSNKSDKGDYASGQSEGGKSPLSMSLGFLKNLTEKKSTRVDSQTPKRRGPKPDSKPALTRRQELNRQAQRTHRERKELYIKALEQEVLRLKENFSCVTQSKQSLAEENRQLKQLLAQHGIQWSGSGGVDEFTNNQSIGYRSSDSQTGSYAPGSTTFSPPPLSQSSNSNPNSAHYDNGSPQMVGAQGGYNANGRRMAQQQAQDSSGVLERPCMDHMQFLVERSNDGDGEFFTGHALMASCPPEPDMDMHPNIPFGHCMPHNHNNAADGADEGPLKQKTWDLSKSDLANLLDLSKRLDLNGEITPVMAWGMVLGHPRFSTLKEVDFKSMSEELLPKVRCYGFGAALEEFEVRDALEARFGMDPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUJ7</accession>
    <name>A0A5N6JUJ7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_006336</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUJ7"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF157">
        <property type="entry name" value="N-ACETYLTRYPTOPHAN 6-HYDROXYLASE IVOC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0843">Virulence</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8291534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="420" mass="48102" checksum="87BF057A5353938E" modified="2020-04-22" version="1">MNSIIVPIVAILFYAAYGIIWRLYFSPIAKFPGPKLAAVSILYEIYHEIILGGQYTFKIRKMHDEYGPIIRINPWELHINDPDYYDELYVAGGKKRDKYFYFTKQFGNSESMIGTVSHDHHRLRRGIMNRYFSKASVVRLETMIQKHVDSLVLKLRSYRDTKKEVNLSLAFSCFTNDVISEYALGKSDNYVENSEDFQTDLQVAISNVSKISHVTKVFPWILPLMQSMPLWAIRYLDPKFVSVVEFQKGLQTQIGAIINGKNTDHKRSSHPTIFHEILSSDLPSNEKSVERLWQEGQTVIGAGTETTAWTLSVITYHVLANPDILSKLLVETNGESGLKELEQLPYLTAVIQEGLRLSFGVVAHLQRISPDQPLMFDKWEIPPGYQCRLYSNISIHAYFPHQPSFLQLASSKTDPYPSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUK9</accession>
    <name>A0A5N6JUK9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUK9"/>
    <dbReference type="OrthoDB" id="3555855at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8292505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="318" mass="35861" checksum="96D2EF39F03EF912" modified="2020-04-22" version="1">MSSSDSPSNTQFNLNIWFEIAYAIGVPAKASHHLTANALRRHREDTMAERSAGYTKSEVSQGVLRRAEILAWINSGALDHGIDGDMNGRPFIVSLPSLWGSEFTDYWSFEYVDMYWRAQPEKFGWVMDWVQDVEGSAGDGELLTDEIYDFFGDDEEIIHRSVSEPEEDSEELSENGQDDGVLIDPTSRPNPRLQMISDLFHVRELRRLGMDDGSPMFPSISPKEFKRNGGPGEKARTKSMNLRERIARDANQRQERLMDDLFPRVIPDQPSTIEGILFELSGPITMGAFLGPQINGRDDETSQDPATKNGSSPTETWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUL5</accession>
    <name>A0A5N6JUL5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_006364</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUL5"/>
    <dbReference type="OrthoDB" id="299997at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000014">
        <property type="entry name" value="von Willebrand and RING finger domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051266">
        <property type="entry name" value="CLCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579">
        <property type="entry name" value="CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579:SF43">
        <property type="entry name" value="ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="135"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="581"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="205"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="365"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="517"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="956"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="234"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="535"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="973"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8291564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1119" mass="123441" checksum="68A1CDD39EA5F535" modified="2020-04-22" version="1">MSKRFLGYRTPSASDTGRNPTSFSRSEQEQKDQVSRLYELGLLSKSDKRSRRQEKDKDKDLPGGARVAGSHPKKDSHKNLVSTRGNSNTSSSTVLLQASKVNRDFKQRAGGGMSGMLDTDRTRNRRERTFVGSECSVCEEPLEHTLRGERILQFSCGHVSHEACFYEYIKESEAQYCPTCNAPLGLDTSRGGNVLDIGKTFRTVSANDQSTRSTPTPTTWESQTVRPPSRESNARTTRARANSQDTHTRDHSRENGSNRDSRESRERMDRYGQPSRISHQRNDSENAPSSVGYPETAISGPPRRHDYDVQAMETNIMSPRASVTRNPIPAPVVGIRSEFPTLNRSRQQQTLTCLITIEVPDNKWRPDPDDIRSAPPLPNIRPEDTYARPPSPAQSAPRFYPYESPEVLDEITDVLRNRVDNWHGLDFNRFGKLRLYGTIRVGKDKQSWQELECFLFAEMLICHLNEVTESGSDNNVLTLSLSVAELPSFHLKFDNRNQLKLWQQALLDLNAIEGSPTRSPDYDLSEPEEEEWNRKSTGPQRASVNSSAYGARSGSIATVPSEYANAPRGLRLPAALHVPVDIVVVIPISSSMQGVKISLVRDALKFMVSNLGDRDRMGLVTFGSSGGAAPLVGMTSKTWNGWQQVLASIRPVGQKSHRADVIEGANVAMDLLMQRRSNNPIATILLISDSSTSDAESVDFVVSRAEAAKIAVHSFGLGMTHKPDTMIELSTRTKASYTYVKDWMMLRECLAGCLGSLQTMSHQNVKLKLRLPEGSPAKFVKISGALQITKRATGKDAEASLGDLRFGDKRDILVQLVIAPDNASQEQLTQDPWDSIVSGLEALGGPVDQEDQRVVSIEEVPLIQADLTWGDILRDGTLTHLPRPSLLAITMLPTSTNQKKHTTWNSAPPIPPHPSVVQRRMELLTSDMLTRALTLVSRGQHDRAQHLLSETRSILKGLGKGGLPPIPPPPSKSPSNNLSSRTGSSSPTNNTPERRRTPSPTSATTVISNHTLGPIPRHQSNDALSAVVTAPGIDPNTVSALDAELEASLEWINQPAVFGRDNRKAVLQAIGVISSQRGYTFRSPVESLWAGRVSGIKRMTDRSREWREGGGEIGITEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWP6</accession>
    <name>A0A5N6JWP6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWP6"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8293373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="67" mass="8130" checksum="F0F56B7642B2F541" modified="2020-04-22" version="1">MYVSCTWLENSENLNTRGDGMNLSFRIQSHSRLIGLDSVYRSLRHLKRVYIPWYIKWFLCLEQQFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWP7</accession>
    <name>A0A5N6JWP7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ribosomal RNA small subunit methyltransferase NEP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_007680</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWP7"/>
    <dbReference type="OrthoDB" id="269804at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070037">
        <property type="term" value="F:rRNA (pseudouridine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18088">
        <property type="entry name" value="Nep1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1280.10:FF:000003">
        <property type="entry name" value="Ribosomal RNA small subunit methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005304">
        <property type="entry name" value="Rbsml_bgen_MeTrfase_EMG1/NEP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636">
        <property type="entry name" value="NEP1/MRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636:SF5">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03587">
        <property type="entry name" value="EMG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8293358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="260" mass="28886" checksum="E209F2BDC358F809" modified="2020-04-22" version="1">MSSPEPRVVKRPRTQSEPPPCLPQVIAEQHVPISSTDKDSQRLIVVLSNASLETYKQSSGGGRPGARAGEEKYSLLNSDEHIGIMRKMNRDISDARPDITHQCLLTLLDSPINKAGRLQIYIHTAKGVLIEVSPTVRIPRTFKRFAGLMVQLLHRLSIRSVNSQEKLLKVITNPITDHLPPNCRKVTLSFESELVRVRDYVETLKPKESICVFVGAMAKGSDNFADELVDEKISISNYSLSASVACSKFCHAAEDAWDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JX10</accession>
    <name>A0A5N6JX10_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_007799</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JX10"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.990:FF:000001">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006746">
        <property type="entry name" value="26S_Psome_Rpn12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033464">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12387">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12387:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10075">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="PCI" evidence="9">
        <location>
            <begin position="778"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="270"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="337"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="420"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="540"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="351"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="432"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="455"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="483"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="548"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8293491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="982" mass="106390" checksum="5B820EB1EACEF75E" modified="2020-04-22" version="1">MDTILGNGAPQPQQPPHIRNGPINGATTRGDGVARSPPTRQNTGHVPCKFFRQGTCQAGQACPFSHDPASTTDNICKYFSKGNCKFGPKCANVHVLPDGRRINYNKNMPPLAPGHLNLGGRINPDPYHGQGSALTSSFARAQGIPPSPYGQPYGPFTTQEDGLVPIIGRQSVDINIPTIDTSYASHAGSNYGSPRDDLMDRFGLGLSPVAAKGLSVMDVPLPASFDSNGVSWIARHGPVASSVPTKFGIDSPPSSVGAAKPSDALRNLHSSAFGDDTRDRFNGTASSPPSEYYGKRTMHSHRMAKPKIMSASLPQEQDWSEAFTFEEDLLPESLNDLMTPAEKARRGSRAAYDESKPSRGFYDEVRSTYSGAGTPINDTPTKFGSPSNASPSRWGPYFQQKHKEEDEKISRASAFGHVGSPLRNSLLHEGASPSSRSIARPNTSGDASPYLASPPRQTSMSIISQQLQRTRLARAESNGSEPSLLSSSAARTTTTPIGSGRSAFSADRQASSSSIGGSGRFTTPIDEEQGDFVFNMEGMDDDEKSQKKSSGGWNIGGSSKSPSSGAVGGGRNISANKTNGSGLDGIDQRPTTVLLTHISSNILRLYHRKFDLGLHLNYLESITQSPLLLLAFSAIQHNTVMTEIWEIQEFALLCCSHQRGSVATLPSPKASYSNITNFSTQLPQQPVFFFKVSISTNNSTIQEVTMSERDLQTIIQKLKSPSTSYQESSSLLSKAKLTLLKLNALTPQASNSSSILSLAREVFETGALVSIRAKDPAAFTRYVHQLTPYYELPAEKFSAQSSGEKNKITGLYLLLLLTQGDYAGFHTELEGLELREIGGKKVEEDKYLGYPIKLERWLMEGSYDLVWRAMEGGKVPSEEYGVFSEILINQIRSEIASSSESAYPSIPISSTKNLLFLPSEGAVVQFAQHRGWLIEDGRIYFPNQKLKNGVNVEAGEVAEEKEVSMTAIENTLGYARELETIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JX12</accession>
    <name>A0A5N6JX12_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007809</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JX12"/>
    <dbReference type="OrthoDB" id="433414at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8293502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="69" mass="7751" checksum="2CB477B0F37F1188" modified="2020-04-22" version="1">MGWNFTNASIPFVCSGRPSPRRHPKGLFVGAIEGWAYYTSRTYVAYVFDDTYFWCLEKDGGNSNGVVCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JX73</accession>
    <name>A0A5N6JX73_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin synthase activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_007796</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JX73"/>
    <dbReference type="OrthoDB" id="4095816at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF2">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="530"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="616"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="647"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="687"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="734"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="749"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="775"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8293487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="813" mass="88835" checksum="E657BB703D093018" modified="2020-04-22" version="1">MSQASVVGHSNRAFEHSNIRTFDAKSQPRSTRGTHYVHNLFQPPARGASLNSPSPQNQNQSQIQDQTQNQNNNMNGYGGAYQQNPSLGATFYPGGSDDFYIPDNVVSPMPQRIMPEVPHNMQDSLANLELGSDGYRQGTSESSRSSASNRNSGPGQNVPLSDEDKEEVLERARPMVLKSSDPEMQLAWAQDALSWVEVASSTYERKNDDPRSPTPKIEHQLRVDAISIVNFLAEQQHPKAEFMKAMWLEFGKFGYRMDKKESFQGYQRAAQKGYARAEYRIGMQFENTMNPAKAIEHYQRGVYLKDSAANYRLGMATLLGQCGIQQDYARGIDLIQFAADTADENAPQGAYVYGMLLARELPNITMPDEYLPYDLNEAKMFVEKAAYLGFAKAQLKMAQAYELCLFGCEFDPALSLHYNALAARQGEPEADMAISKWFLCGYEGIFEKNEELAYTYAQRAAETEMATAEFAMGYFYEIGMYVNKNLEVASQWYDKAAKHGNHDALGRINSIRANHTLSKGDHGAAIQRIKSTHGSRRGARPERFTQPNAPPMPTMAEDPSPTPPAHNSKPKFKKGAPAGIRPISIAPYPEDDMSPGGRGGYPPRSPRYASQDGLRPSTSSSNPASDRPSSAFGIRPQQQPPPHLGITHQNTEPIRSSSPMGAMSSQGRNPSPNRAPNIPPMSFEPGYQSSQQRPPTSGSSRPGTAQSSQSAYGSRQFSSPNPGPGQNVAPPRGTSMTPVSNPSATNRKPISNSISSQPSSRQPSISSPSVSSPSTPAPVAAPPKPSAPAKKGPATFEEMGIPQTKSEGDCVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYR8</accession>
    <name>A0A5N6JYR8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ketoreductase (KR) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_009669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYR8"/>
    <dbReference type="OrthoDB" id="5336600at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669">
        <property type="entry name" value="5-KETO-D-GLUCONATE 5-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G03445)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8294237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="26904" checksum="4DB80075B6F2645F" modified="2020-04-22" version="1">MTSLKPRNIIIIGAGPLMSRSLSLYLASHKWQIILISRKHPSLLSYAAEINTFHPEAPKVLVHTGDASIPSSLTEALNWAAEQVSGKVDVVCYNAAHVAPSPLLELQPETLVQDFNITATGTLVAGQWFMNHANTSHLDEGEHPLFLVPGGMLDRYPDPNISALCATKSANLSLRLGRSIIMRRGWSGFLRRFGCRREVMELREQMARISLIWMYYWENDGRIRELSMILKNIIEDVLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYS1</accession>
    <name>A0A5N6JYS1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_009716</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYS1"/>
    <dbReference type="OrthoDB" id="77601at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04514">
        <property type="entry name" value="Taspase1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.30:FF:000007">
        <property type="entry name" value="Similar to threonine aspartase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037464">
        <property type="entry name" value="Taspase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF8">
        <property type="entry name" value="THREONINE ASPARTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="2">
        <location>
            <begin position="72"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8294291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="255" mass="26963" checksum="AE5E054B4B4C385D" modified="2020-04-22" version="1">MFSEPNISLSTGSSAIERPSSTDGYASPVDQEKVIEMHSALLNLAQEGTIEGPNESTIESTPKKLDVDLITDTVGAIAIDMYGRIAAASSSGGIGMKHRGRVGPAALVGIGTAVIPCDERDEDQVSVAAVTSGTGEHMATTMASQKCADRLYHNTRRARGGQDMEANEDEAMESFVQADFMGHPGVCGSNSAGAIGVMAVKKTQYGYFLHFAHNTDSFALASYASNEKDAKCVMSRLGDHGNVVRGGRKIRTEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYS2</accession>
    <name>A0A5N6JYS2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">F-actin-capping protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_009729</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the F-actin-capping protein alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYS2"/>
    <dbReference type="OrthoDB" id="340550at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008290">
        <property type="term" value="C:F-actin capping protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1140.60:FF:000004">
        <property type="entry name" value="F-actin-capping protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.210:FF:000003">
        <property type="entry name" value="F-actin-capping protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.60">
        <property type="entry name" value="F-actin capping protein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.210">
        <property type="entry name" value="F-actin capping protein, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002189">
        <property type="entry name" value="CapZ_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042276">
        <property type="entry name" value="CapZ_alpha/beta_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042489">
        <property type="entry name" value="CapZ_alpha_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017865">
        <property type="entry name" value="F-actin_cap_asu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01267">
        <property type="entry name" value="F-actin_cap_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00191">
        <property type="entry name" value="FACTINCAPA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00748">
        <property type="entry name" value="F_ACTIN_CAPPING_A_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00749">
        <property type="entry name" value="F_ACTIN_CAPPING_A_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0117">Actin capping</keyword>
    <keyword evidence="6 8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8294309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="323" mass="35902" checksum="5C41463008FDD148" modified="2020-04-22" version="1">MRILYFLEVPALIFNSIPQTSFRMSSQVKTISAFVEGAPPGELADVIADIKALTIDTPNLVSELGPAFQRYNEEQFATVKLPGSSQNVIISSHNSLGDGRYYDVESSSSFAFDHTTQKASVVQSHVLEGSQVDLVKSILKNLGPHVAEHFPNASYGAFPIEDDSKIAILVVANKYSPNNFWNGRWRSLYIYETLTSSLTGSIKVDVHYYEDGNVRLLTTKPISATALSSASSVVREIAVAEQKYQEEINKGFNNLSEGAFKGLRRQLPITRQKIEWEKIAGYRLGQDIGAVEGVAVEGVTVERVVVERNDMIRWLEQEHAMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYS3</accession>
    <name>A0A5N6JYS3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYS3"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8294312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="114" mass="13076" checksum="E08B3C77C365B86C" modified="2020-04-22" version="1">MARTGAQRISKAQKIRVGEVVSRGRERDEMCSLMMRHAYQFLRGIFNILRFILRIQMMGCLGALRRPSSRPPLSYHIWREVAMDTYNLESEDMGTCESPILTPPSSKGRCIALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYS7</accession>
    <name>A0A5N6JYS7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UNC-45/Cro1/She4 central domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_009718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYS7"/>
    <dbReference type="OrthoDB" id="5574718at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45994">
        <property type="entry name" value="FI21225P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45994:SF1">
        <property type="entry name" value="FI21225P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8294296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="428" mass="46494" checksum="E7B4517B8E7B3A70" modified="2020-04-22" version="1">MFKKMLSTDTSQQSSIEGLAYASLQPKVKEKLASDTKFLVNLVKALNDAPAKSPATYGALTILVNLTTYQPPLTEEQKKLGQLKAYANASKSTLKPDPLNDDNHVVKRCQAVFEAGIIPVLVTHSQHGSIASLTLVTSIIFSLSKTTKIRGQMAQQGAVKLLLHAYSVFPSDSILARRTTAHALARILISTNPQHVFGGTNPLSLLSAIKPLLLLLEDDPTVEHRDLLPVFESLLALTNLASTDDSARNPIIRLAWPQFDELLLSNNKMVTRATVELICNLMLSPEGVSNFSDGSKQASQRTHILLALADAEDFPTRRAAGGALASLTEWDTAVNAILERERGVALLLGMCKEDEEEMRHRGVVCILNVLTAPNKVGEWGTKKVKENGGLEALKECLKKSRSQQVLEITVEALKKLIGDEGPGKLLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYT3</accession>
    <name>A0A5N6JYT3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">OPT superfamily oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_009619</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYT3"/>
    <dbReference type="OrthoDB" id="627262at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645:SF0">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="631"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="202"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="425"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="425"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8294180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="707" mass="76155" checksum="C61808A26F18F054" modified="2020-04-22" version="1">MAPDRGTTQSPANYRSTSIRTSEHNDLALRRRRSELRQFIAAHAEEGQNFTVRGILVGLGVGLIICFSNMYFGLQTGWVSSMAMPASLIGFAFFKTLSKHLDLPFTPVENVLVQTVAGSMGTMPLGCGFVGVMPALNYMMKPEEQGPIFLSTWKLILWSLGLCFFGVVFAVPLRRQVIIKEKLKFPSGTATALMIGVLHGKETNASEPPVSSSGGPDESDERESRSFTDESVADVEEVSKAEGSSWKSKVKLLVISFSISGFYTLATYFFPILRKLPIFGTAIAQNWLWTLNPSLAYVGQGIIMGPATTTHMLLGAVVGWGILSPLAKNRGWASGPVSDWETGSKGWIVWISLAIMLADSVISLGYIALNPLINNGGYYISEAQRKIKRQDWWGLVSIGAPQSTTGYAPINGEDSGNHREQYASTALDESSFPGNTHQPETKDLPEPDAPPEHLVNSRTVWIGLILSITFCVASIRVVFGELVPLSASIIAVLMALILSIMGVRALGETDLNPVSGISKLAQLFFALIIPQSNNNSVLINLIAGAISEAGALQAGDLMQDLKTGHLVGAAPNAQFWGQIIGSAVGAVVSALIYKLYTNVYQVPGDLFQVPTGYVWIFTARLVTGKGLPHMAAQWAIGAAVIFTGTTLLRIYATGTKWHSWIPGGIAVAVCTTLPHSLSLAQSAGSSTYTGVPTAKEKKLPLWYWLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYT4</accession>
    <name>A0A5N6JYT4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYT4"/>
    <dbReference type="OrthoDB" id="2149705at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8294298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="317" mass="34405" checksum="9034FEDE40EEDB4C" modified="2020-04-22" version="1">MAVIGPSKAPGDITTLDGLGNSEFNAGEKRSKFAYEILELYALANPMTFEELKSRQWFKAAPQKYARVPPAVLGELIANLLPPLFTQSEPSPPPSTRNSSEIVHSTPILHRTSSSSTESQEVQNQITNNIAQFTQIQAPPSSPPAAIPAAIINVPSSQTHVARESQASTVDYTQTQTPVTPRYHRKESPFPDLIPESPTKPIFIPSSSPASSQAQVLPPVVPRSAPTTAIETELDSQSEDDHEENSVPIVSRPSSGRGIEAERENGNEAKEEQHHPSSTPQPYSLIRSSQIMTRSQMMREQDSLMDGEITGPPPTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYU3</accession>
    <name>A0A5N6JYU3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">F-actin-capping protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_009729</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the F-actin-capping protein alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYU3"/>
    <dbReference type="OrthoDB" id="340550at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008290">
        <property type="term" value="C:F-actin capping protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1140.60:FF:000004">
        <property type="entry name" value="F-actin-capping protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.210:FF:000003">
        <property type="entry name" value="F-actin-capping protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.60">
        <property type="entry name" value="F-actin capping protein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.210">
        <property type="entry name" value="F-actin capping protein, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002189">
        <property type="entry name" value="CapZ_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042276">
        <property type="entry name" value="CapZ_alpha/beta_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042489">
        <property type="entry name" value="CapZ_alpha_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017865">
        <property type="entry name" value="F-actin_cap_asu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01267">
        <property type="entry name" value="F-actin_cap_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00191">
        <property type="entry name" value="FACTINCAPA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00748">
        <property type="entry name" value="F_ACTIN_CAPPING_A_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00749">
        <property type="entry name" value="F_ACTIN_CAPPING_A_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0117">Actin capping</keyword>
    <keyword evidence="6 8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8294308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="300" mass="33163" checksum="D5375A50B3EFD7F3" modified="2020-04-22" version="1">MSSQVKTISAFVEGAPPGELADVIADIKALTIDTPNLVSELGPAFQRYNEEQFATVKLPGSSQNVIISSHNSLGDGRYYDVESSSSFAFDHTTQKASVVQSHVLEGSQVDLVKSILKNLGPHVAEHFPNASYGAFPIEDDSKIAILVVANKYSPNNFWNGRWRSLYIYETLTSSLTGSIKVDVHYYEDGNVRLLTTKPISATALSSASSVVREIAVAEQKYQEEINKGFNNLSEGAFKGLRRQLPITRQKIEWEKIAGYRLGQDIGAVEGVAVEGVTVERVVVERNDMIRWLEQEHAMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2024-05-29" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0F3</accession>
    <name>A0A5N6K0F3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0F3"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8295253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="98" mass="11045" checksum="DE28A7DD2F723E3B" modified="2020-04-22" version="1">MYTDATTGIHQPSNQAINQLNHPFLHSLLDHLIIIHPQNIVSVEPIPIHTHTISQSLHQNNQYPPLTLDIGKKDPFPNSFPVVYGHTHTHLSSCLFSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2C1</accession>
    <name>A0A5N6K2C1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA/RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2C1"/>
    <dbReference type="OrthoDB" id="2017974at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005697">
        <property type="term" value="C:telomerase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000202">
        <property type="entry name" value="Unplaced genomic scaffold supercont1.7, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018834">
        <property type="entry name" value="DNA/RNA-bd_Est1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045153">
        <property type="entry name" value="Est1/Ebs1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696">
        <property type="entry name" value="SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696:SF0">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN EST1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10373">
        <property type="entry name" value="EST1_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA-binding" evidence="2">
        <location>
            <begin position="458"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="839" mass="94939" checksum="647AC4585CBC9B64" modified="2020-04-22" version="1">MYLLIQNPSPNPARNEQSKGRCKRPMDTTSAPQYENNSILGLHILAKKRATRDDSQPRKSSNNEAAQSNPSPPQVQSKRPLNTPQTTRSLSGLQALNLGPNEDNPMEDEEVTIDQPRKRAAVGDGISAGSASPFRETSDSPPPRRSLARPSTGPFSPSDTEARRQATKGQLWTPDQDSPFTRSSFDPSNIASIQASKSRAQALKPVNRRSMKTSSPQVTPRPVPNTSQQHQHQHQHQHQHQHQQQQQHHHTQVNTPSAILPSRAVSEAAPRSHSEEYSIILQPETRPISQEQLVAEVKGIYAGLVMVEAKCIEVDNKQATLAQSDPTSQPPRLNNEQWQALIALHRTLLHEHHDFFLASQHPSASPALRRLASKYAMPARMWRHGIHSFLELLRHRLPGSLDHMLAFIYLAYSMMALLYETVPAFEDTWIECLGDLGRYRMAIEDDDIRDREVWTGVARHWYSKASDKAPTTGRLYHHLAILARPNALQQLYYYAKSLCVVVPFTSARESILTLFDPVLNAENGQGQYRLPPLDTALIRAHGHLFTNRTMDRFQPAVQEFLALLDSQIGRVTKKFMEQGSHIAISNNVAMLGFASKENPLMKAIISPEDKSADIDMDVTHDESSPSMIAFKFAQSLSNSTLEIVLQRIGDPNVLPFIHVSLVFIYRMSHFPGAMDLLAPAFPWQSLAIMLNTLLKFYKSLSRIVDSKFPLPEKDDVRPFPEDFGMRGLLWAEKYFPERWFLNEKTDEEEKYHELPSMLDQRKERILWLACRIADAGPWINFDSYKLEFSVQSSDTDIEFLKSRSLTFASATTNDTLTRGDTWIYIKLRVSSQQVVQHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2C7</accession>
    <name>A0A5N6K2C7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2C7"/>
    <dbReference type="OrthoDB" id="5401193at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="412" mass="43875" checksum="638A74979F4CD5AA" modified="2020-04-22" version="1">MSYYDNQQWSAGAAGQPSWEQQTPPARSGTSSVVQREDSTAFSTQIEEVDRAIDNLVKSGKMFNLPAGGRRDSMPLVGPSRTFPEQFDPRMTAGPPRHHSVSDFGDARSFSGSNLQNFYASQRHQPSRGANEAEQVMQAKRRMAAQRERELRNYHQEQQYNRTEILGGKPDRIASPGSGMNEEERRELIARQRSALYGEGPAFNAENGGFDENGTPRPTTQGSTSQTLNAPPGAIRGHSPLAFDHFNAQASQGENSNQQNATEPQSTTTAQAPGKQRSRANSTSSPSSNPTSFSLFESAAQQSSRTSTSSPGGSPPRQGGKAGAGGVAPIGTRPSGQAANPALNKRSTTPLPSPLSYGYAANDSTTESKDARTTSASSNPNPQGQTESGLGWGSKSGVWGNKNLGVQASVWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2D1</accession>
    <name>A0A5N6K2D1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2D1"/>
    <dbReference type="OrthoDB" id="3562925at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="346" mass="38553" checksum="896B876C68483BB8" modified="2020-04-22" version="1">MSPPPSVYLHAERERERRRTRTRTHHDIPNHSPSTASTLRSPPDNLSVDSLGKPQPATETQHRSHRIRHSRPSSQSIHHASNQPPSRNRSSESFPSTTTLPYAPNRFPPSPPYSVSSPATLSRASTLISNHAPPIALEFLNFLDDLGILVLCKPLLELCNVDWIPLFDDMGIFYLCEPIGAIKRILRKLKIGRVDRDKGAGSCLGSKSTWERDTVSWLSSMESAIKSSRESRDCKKASKRHSTGEEKSRRSEDEGRKVPITTEREVDESVSGIGTERISGANRRRSERAASSVAASGLGQGWRGAPRAKLKIRSLTTGSNYRKKIFRNQEDRVGIVRNVILTLLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2D2</accession>
    <name>A0A5N6K2D2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2D2"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="123" mass="14122" checksum="0B24515EA7EF0B24" modified="2020-04-22" version="1">MHVRVSTNVFLLYGHSGELLLSEFLYRNWETSKFIPSYQLFKSSIPQNTTNIKTPQPDHKKISSHRKSRNIETSKHRNIETSKHLIRIQGLSFTSFTLSNALFTITSFVGLCNIIDLGIPQQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2D7</accession>
    <name>A0A5N6K2D7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2D7"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024962778" evidence="1">
        <location>
            <begin position="23"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="114" mass="13226" checksum="E9476210D2FA4B94" modified="2020-04-22" version="1">MGFKLVGFIFDIQLACIHIGKAQKCDTSFKVLVLMARGDAGIVGQQGIQREEYDQEAMGLECMFIVWMCQKLREHRDEYERSGGGMRKWPTGSWFYIPSIVKCRQKTDRNNDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2D9</accession>
    <name>A0A5N6K2D9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2D9"/>
    <dbReference type="OrthoDB" id="3724345at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8296326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="83" mass="9837" checksum="6FE94E0FF8B514F8" modified="2020-04-22" version="1">MNHDYLYAAANDDRHPHQERSSRLMIRINNYLPTHIPSSPLFLHKNFLMLNNLGFSMGLAWDRTGHVHFLWYRYSCIDSDVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2J0</accession>
    <name>A0A5N6K2J0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2J0"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8296378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="124" mass="13877" checksum="FD55B1CA0AF3A881" modified="2020-04-22" version="1">MSHTIIINPSHPSIQSPCSSSLNFPISDQSSHPAYFQSSSSKASVILRYTLVLFPCPSPASKDFLLFSYHYYCAPPVLSEDLIPGTALLHLTLVIKDRPQPFIHLKSRNLHLDATCFSQWSLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4G0</accession>
    <name>A0A5N6K4G0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">dual-specificity kinase</fullName>
            <ecNumber evidence="1">2.7.12.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_002634</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.1" evidence="1"/>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4G0"/>
    <dbReference type="OrthoDB" id="283111at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14134">
        <property type="entry name" value="PKc_CLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000612">
        <property type="entry name" value="Serine/threonine-protein kinase AFC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="198"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8297272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="570" mass="64603" checksum="DED0B8F8ABDB477F" modified="2020-04-22" version="1">MVSSASQAPPPHKRQRSKERQPDWDKFYENGLPKETNNSAVAANSRHAAKKRKRNDAYDPVYQLDPSIDPSPQYKSESGSNSTISTDRTTSAIHTTAATSLGSHSSNGQNGYEAAELTGQKRKRTNTRLQLANEAKRKELEVNGDAFSNYIPPPKPPIKSRDVPVRQVLDHSYAKNSKVDDEDGHYIVVPDTNLTTQYSVLKLLGQGTFGKVVQAKDHLDNGKLVAIKIIRSVQKYRDASKIELRVLSTLKANDHENRNRCIHLRDCFDYRGHICIVMDLLGQSVFDFLKGNSFVPFPNSQIQSFARQLFTSVAFLHDLNLIHTDLKPENILLCNSAYQAFTYSRKIPSSSTTVSRQAAQRKVLLDTEIRLIDFGSATFQDEYHSSVVSTRHYRAPEIILGLGWSFPCDIWSIGCILVEFFTGDALFQTHDNLEHLAMMEMVCDKKLDSHLIQQVNAMAKRNGGNPAQKYFRRLKLDYPTADTTRASRRFVKAMKSLDEIIKDQGRFSRNFLDLLKRIFVYDPSERITAKQALQHPWFKEAAIADDGTEATKIRLQRQSGTYTAPQRQHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4G1</accession>
    <name>A0A5N6K4G1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_002609</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="8"/>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4G1"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000164">
        <property type="term" value="C:protein phosphatase type 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000004">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="9">
        <location>
            <begin position="147"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8297240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="334" mass="38712" checksum="02FC234AACC1AC36" modified="2020-04-22" version="1">MRARSRSELKLKPQQIYDLKTPLRTNAMAEQDVDLDSIIDRLLEVRGSRPGKQVQLLEQEIRYLCTKAREIFISQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFTMHGGLSPDLNSMEQIRRVMRPTDIPDCGLLCDLLWSDPDKDITGWSENDRGVSFTFGPDVVSRFLQKHDMDLICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAEKKQKFGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4G4</accession>
    <name>A0A5N6K4G4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7593 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002582</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4G4"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056015">
        <property type="entry name" value="DUF7593"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24513">
        <property type="entry name" value="DUF7593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7593" evidence="2">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8297207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="228" mass="25873" checksum="79F24417C7E1A2EE" modified="2020-04-22" version="1">MDMKESIWPLVLAKYSCGLTLDAGGGPPYVPEENAKSLFLGLDLFFVKVSEFMFIVPNFPHLRGLEMAVEYHELVPLGTPPVNKFEQDSDYDPRHPFWPAPQRYLDGALVTRWKFETKTSTKPFPEPKVPRRDFSRLICNEKDLTRSQRLFNSGPNYQESPQGNRPDDHDQDVGITPPHSDRSRSLNEEAVSQESFAEPTHLLHHPELPNGGPSVPNGLMRHEANTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4G7</accession>
    <name>A0A5N6K4G7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_002586</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4G7"/>
    <dbReference type="OrthoDB" id="9909311at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007889">
        <property type="entry name" value="HTH_Psq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF70">
        <property type="entry name" value="HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04218">
        <property type="entry name" value="CENP-B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="4">
        <location>
            <begin position="194"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="362"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="566"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="287"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="403"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="422"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="482"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="592"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8297213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="601" mass="65927" checksum="592560B5CF1D19D7" modified="2020-04-22" version="1">MMAHIGMDHEQHHNPQENGYGGEGWPEMGGSYNSSQHQSPIYENSGQYGYLQSHHPMPTESQYPRMPPPPPPPPPQPAPPTYHTHHQQLLPLIMPNHPTWPSMLTNPASSQAPPVAIPPANSGKPPKLPAIHATPTPRKTLTDSDRRRMCQYHEDNPTVKQTEIGAMFGVERSTVSKVLRQREKYLFPEDRSLSPVKRAKGKFPDIERALSNWVRNTQKQGIPLTDAAIKEKARFFATTVGNNESHLKTNSTSWLEKFKQKNGIGNLRRRASAADIGSLSERMAINIDSSKSSGSRTSNVVSPTSPLQSPLLLASAKSSEDLRSHHMHDSLNSYFDFTQAPNYKQHSNSHSTASLSSAFTDNNPSSFSGGPTSPTTPFAFSPDGSTGSWMPSQQSRVTPQLKNNENSNTGENLNNEMDANDLGSNFQRPRSQTFPTLAIDPSFIASQGTDPMTPKYNLPDTAPSSAVESPVHELGPPFGLDSAISPRSLHHSSSNSSMAHPPASLTPISGLQSPPHLSTPNSPTQDDARRALDTLLNFFQQAPTGLVDQNEYLTVLKLTEKLRIQQQNPGPLPGGLHRISEQEQECESQPQNMKMEQSTAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4H2</accession>
    <name>A0A5N6K4H2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">EYC80_002622</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4H2"/>
    <dbReference type="OrthoDB" id="10259843at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010467">
        <property type="term" value="P:gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17947">
        <property type="entry name" value="DEADc_DDX27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="254"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="285"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="489"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="116"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="672"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="635"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="254"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="213"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="672"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAB8297256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="691" mass="75794" checksum="DFF927046B6E7341" modified="2020-04-22" version="1">MAPKRNRDDDFVLTLSDNEGEDLNNFVEEELPSDPSTNKKRKRNDDILLEEEGIWGIKDADDGAMDSDFEFALEADGKGGADLEEFEGWGFDGAKKGLNGGDKKAVDIDEIIARRREKKKSAGKKGDKEDEVMADAGDVVAADEEQDAPEGMDFEDEDDEFMAEDGFGMGAGSAEESGAEDDSEASDNEETGDEDDDSDNDSVASPAPHPDDAASEASDDDEDVDEDPEEAAKREAFFAPEEKPVKGAKPELNSTFQSMSLSRPILRGLATVGFTQPTPIQSKTIPVALLGKDVVGGAVTGSGKTAAFIVPVLERLLYRPKKVPTSRVAILMPTRELAIQCHAVATKLASHTDIKFCLAVGGLSLKVQEAELRLRPDVIIATPGRFIDHMRNSPSFTVDTLEILVLDEADRMLEAGFADELNEILTTIPKSRQTMLFSATMSSSVDNLIRVGLNRPVRLLVDSQKSTAGTLTQEFIRLRPGREGKRMGYLLYLCTNVYTDRVIVFFRQKKEAHRARIIFGLSGLKATELHGSMSQEQRIKSVEAFRDGKASFLLATDLASRGLDIKGVDTVINYEAPQSHDIYLHRVGRTARAGRSGRACTIAAEPDRKVVKAAVKASRTQGAKVVSRVIEASEADSWSEKVDEMADEIEEILKEEKEDKILAQAEMEVRKGQNFMDHEAEIKGRPKRTWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4I0</accession>
    <name>A0A5N6K4I0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_002609</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPP phosphatase family. PP-1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="9"/>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4I0"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000007">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="10">
        <location>
            <begin position="147"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8297241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="449" mass="51714" checksum="F29110325510DF99" modified="2020-04-22" version="1">MRARSRSELKLKPQQIYDLKTPLRTNAMAEQDVDLDSIIDRLLEVRGSRPGKQVQLLEQEIRYLCTKAREIFISQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFTMHGGLSPDLNSMEQIRRVMRPTDIPDCGLLCDLLWSDPDKDITGWSENDRGVSFTFGPDVVSRFLQKHDMDLICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAEKKQKYVTAGGLGSDADKLNSRFSTQRISPSTNMRPSIASLWDPSSHQTFASILQTSISTKHTYLRDTFRTLPFVSLFLSLPNATQICTQQLFHYAFSTTNIKDTTRYAFPHEFFGRITTYHFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4N8</accession>
    <name>A0A5N6K4N8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4N8"/>
    <dbReference type="OrthoDB" id="3057168at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF1">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="1">
        <location>
            <begin position="132"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="674" mass="76462" checksum="9D00D27432BD56D5" modified="2020-04-22" version="1">MPGKWSSSQNPSNNGQVYPLTWQNAKAGLTNEKHQNSMILDEIYLNSIVWYEIILHLPICNSILERTCADPKSLDNLSIYQHIDISLHIYLSNLQSHHFCGHSFRTLHSLRHYQAIQNKMDDFEGQTYLQPKRIILCCDGTWMDSDDGFNKPTLIPYKPTGSLQTPSNVTRLSRALRRYGRDGTHQIIYYHSGVGTGSSMMDTISGGMLGTGISENIREVYSFIAANYTPGDEIILVGFSRGAFTARSVAGMISDIGLLTRHGMTNFYAIFKDQENFRNPDYKDIFPELPFPHKPKDGDEYKKRLVDEGLTRVYDPNGSRIRVHAVAVWDTVGSLGIPNIALLAKLGLPHSTKEYKFHDTNLSGYIRHAFQALALDEHRRPFSPAVWEIRDFDDDPTDLRQVWFPGSHANVGGGYDDQEIANITLAWMMDQLASIGVAFHDDAIDIIFQKSVHYYESLPPPSTSIFRFSKPINEWATPEIYEKHHPVRPWALGKIYNSDTGIWTLAGKETRTPGLYKRLDPDTGISTGIPMTHTNERIHSSVRIRLDLGGLGEEDMTKYKCPALLRKGPWRLDQIRIKVTDPIPPTATWGPTAPAALDDERTSDLRWVWEYDGPERNAPTIQTMIEENLGPYERKLLLLNKGKGMFHKVIDEAGPDDRRAIIAAEFDARREYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6J5</accession>
    <name>A0A5N6K6J5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA replication licensing factor MCM6</fullName>
            <ecNumber evidence="11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_001946</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="11"/>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6J5"/>
    <dbReference type="OrthoDB" id="1744952at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990518">
        <property type="term" value="F:single-stranded 3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902969">
        <property type="term" value="P:mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1640.10:FF:000009">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008049">
        <property type="entry name" value="MCM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01662">
        <property type="entry name" value="MCMPROTEIN6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="477"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="181"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8298204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="646" mass="70412" checksum="84AB20EECCC89656" modified="2020-04-22" version="1">MASVMMSDAPTPDFGNSSRAGTPKARRHRGSSASGRPRGPPSESAGAMSDDEGFADDAIPQNTNRPRKSDRPIPRVEDAIGQYVQLTFEEFLESYVEDPILSGATPSSAMTTDKYYIAQIHGLRNYQLSTLYVDYTHLSSYKGGALAEGIVEEYYRFLPFLTKALHNMIAKYEPRYFRDHRQPTASSNQTSSGASNAASASQSDFQGDKTTNQQTDKLFALAFYNLPLVTRVRHLRTANIGQLLSISGTVTRTSEVRPELSLATFICENCKNVVPNVEQTFRYTEPTQCPNLECNNRQAWRLDIRQSTFVDWQKVRVQENSSEIPTGSMPRTMDVILRGEIVDRAKAGEKCIFTGALIVVPDVSQLGLPGVRPMAIRDTQNRSGDASGVTGLKALGVRDLTYRLAFLSCMVTPDTSTQGAAANQQLNGQSNNILASLNQTAPVDPNEPGDHAQEAVLASMTHAEIEDLKEMVHSDHIYSRLVNSLAPMVYGHEIVKKGLLLQLMSGVSKVTPEGMQLRGDINICIVGDPSTSKSQFLKYICSFLPRAVYTSGKASSAAGLTAAVVKDEETGEFTIEAGALMLADNGICAIDEFDKMDISDQVAIHEAMEQQTISIAKAGIQATLNARTSILAAANPMSAMRQWIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6K1</accession>
    <name>A0A5N6K6K1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DHHA2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_001923</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6K1"/>
    <dbReference type="OrthoDB" id="374045at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.20">
        <property type="entry name" value="DHHA2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.10">
        <property type="entry name" value="inorganic pyrophosphatase (n-terminal core)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004097">
        <property type="entry name" value="DHHA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038222">
        <property type="entry name" value="DHHA2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112">
        <property type="entry name" value="BNIP - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112:SF39">
        <property type="entry name" value="EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02833">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01131">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHHA2" evidence="5">
        <location>
            <begin position="218"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8298176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="426" mass="48074" checksum="C4EE457D101CE168" modified="2020-04-22" version="1">MNRLYKDLDSICSAVLLAYLRTYSPRNRTKALYIPLSNLPAADLGLRPELNPVLERAKLRVGDLLSLDDLRGGLNAEGTKWILVDHNALQGELGKVYEERVRGCIDHHDEEGKVPNKEVCEAEGEMRIIEKSGSCASLVIGWGKGDLTEMGKGGEGDLRSWEAELAYLALGPILIDTNNLQSKDKTRDSDIDAVQFLESLIEKAPKISETPWNRDQYFSSITTAKEDIGQMGLRDILRKDYKQWNEKEMNLGISAVVQDITFLLSKAGSNEKFLQVLGEWGGEKKLDICAVMTTSQREGVFRRELLVWALGEKGVECLKRFKRDGEEKLGLRVWGEGLLDLNKNGNGEKEMRNCWWQERIENTESEESHSLPGTSTAFHVSSIFPEPLMLGLNWHNQEHSENLDIAHDALLTITKKILCHELRQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6K6</accession>
    <name>A0A5N6K6K6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_001958</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6K6"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000001">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF85">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="9">
        <location>
            <begin position="26"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8298221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="299" mass="33894" checksum="F99B1CBB07BD8900" modified="2020-04-22" version="1">MLKAMGINDLLHFDFMDPPPTNTMLTALEELYALSALDDEGLLTRLGRKMADFPMEPSLSKVLIAAVDLGCSDELLSIVAMISIPTIFYRPKEKQAQADQKKAKFHDPHGDHLTLLNVYNSWKQNKFASPWCFENFIQARSMKRAKDVRDQLLKIMERYKHPIVSCGRNTDKVRQALCSGFFRNSARKDPQEGYKTLIEGTPVYLHPSSALFGKQAEWVIYHTLVMTTKEYMHCTTSIDPKWLVSAAPSFFKVADAGKLSKRKKAERIQPLYNKFAAEDDWRLSAQKRQGRGGGGGTWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6K7</accession>
    <name>A0A5N6K6K7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">V-type proton ATPase subunit D</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">V-type proton ATPase subunit d</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10 11">Vacuolar proton pump subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_001907</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Vacuole membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6K7"/>
    <dbReference type="OrthoDB" id="7676488at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016471">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3240:FF:000002">
        <property type="entry name" value="Vacuolar atp synthase subunit d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="V-TYPE ATP SYNTHASE SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="214"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="216"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="255"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8298152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="265" mass="29635" checksum="2D0963EC0B37EFE3" modified="2020-04-22" version="1">MSGAGNREAVFPTRQSLGLMKSKLKGAQTGHDLLKRKSEALTKRFREITRRIDEAKRKMGRVMQIAAFSLAEVTYAVGGDIGYQVQESAKSARFRVRTKQENVSGVFLPAFESYTTEGNNDFGLTGLGKGGQQVQRCRETYARAVETLVELASLQTAFVILDEVIKVVNRRVNAMSDSLPYYPYPSTENTIKYINSELDELDREEFFRLKKVQNKKQRDTAAQDAEMKAKKEAAAEKDKANGSDKENSTHTGDILGDEEDADVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6K9</accession>
    <name>A0A5N6K6K9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA replication licensing factor MCM6</fullName>
            <ecNumber evidence="11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_001946</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="11"/>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6K9"/>
    <dbReference type="OrthoDB" id="1744952at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990518">
        <property type="term" value="F:single-stranded 3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902969">
        <property type="term" value="P:mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1640.10:FF:000009">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008049">
        <property type="entry name" value="MCM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01662">
        <property type="entry name" value="MCMPROTEIN6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="477"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="181"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8298203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="699" mass="76506" checksum="7C62E2134D51E077" modified="2020-04-22" version="1">MASVMMSDAPTPDFGNSSRAGTPKARRHRGSSASGRPRGPPSESAGAMSDDEGFADDAIPQNTNRPRKSDRPIPRVEDAIGQYVQLTFEEFLESYVEDPILSGATPSSAMTTDKYYIAQIHGLRNYQLSTLYVDYTHLSSYKGGALAEGIVEEYYRFLPFLTKALHNMIAKYEPRYFRDHRQPTASSNQTSSGASNAASASQSDFQGDKTTNQQTDKLFALAFYNLPLVTRVRHLRTANIGQLLSISGTVTRTSEVRPELSLATFICENCKNVVPNVEQTFRYTEPTQCPNLECNNRQAWRLDIRQSTFVDWQKVRVQENSSEIPTGSMPRTMDVILRGEIVDRAKAGEKCIFTGALIVVPDVSQLGLPGVRPMAIRDTQNRSGDASGVTGLKALGVRDLTYRLAFLSCMVTPDTSTQGAAANQQLNGQSNNILASLNQTAPVDPNEPGDHAQEAVLASMTHAEIEDLKEMVHSDHIYSRLVNSLAPMVYGHEIVKKGLLLQLMSGVSKVTPEGMQLRGDINICIVGDPSTSKSQFLKYICSFLPRAVYTSGKASSAAGLTAAVVKDEETGEFTIEAGALMLADNGICAIDEFDKMDISDQVAIHEAMEQQTISIAKAGIQATLNARTSILAAANPVGGRYNRKTTLRANINMSAPIMSRFDLFFVILDECNETVDRHLAEHIVGIHQLRDEAVQPEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6L3</accession>
    <name>A0A5N6K6L3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_001728</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the xlnR/xlr1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6L3"/>
    <dbReference type="OrthoDB" id="5365785at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000004">
        <property type="entry name" value="Xylanolytic transcriptional activator XlnR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051439">
        <property type="entry name" value="XlnR/Xlr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47663">
        <property type="entry name" value="XYLANOLYTIC TRANSCRIPTIONAL ACTIVATOR XLNR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47663:SF1">
        <property type="entry name" value="XYLANOLYTIC TRANSCRIPTIONAL ACTIVATOR XLNR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="10">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="59"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="142"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="508"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="687"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="508"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="522"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="698"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8297947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="909" mass="99571" checksum="0C22FE72FD54E705" modified="2020-04-22" version="1">MLSNPLHRFSGYNTMPSNNMISTGHLPSNHMHTTGLDTLAHGSQYAISQLHQQQVDLRQSSQAHRNGISKHRQHPYAMGMPGSNATSARGTGNSGPIRRRISRACDQCNQLRTKCDGQSPCAHCVEFGLGCEYIRERKKRGKASRKDLAQQAAAAAAANGQKSPTDQSPEERSPVESRNEPSSATSITNENVEFPRHTPSRSLSLNTAGIEKPSARELMKGRIRAGSLESLTEVPSQVHQPHVSRAEVDQTGSPGSLNLHGYSNMHGYRSTLNPHMMSGSGSHANFNTSQTGYSDLPYAIQGQSPPNYPGNTPGQFRLAESPLPGFPMGSDAPSPELQCTPTISRATALGASPWQYHPNTFSLQCTPALLASILWVVAQTSDSAFLTASPSSRGRICQKLLELTVGLLKPLIHGTTGGSDNPSNFPNTIINGVALGGLGVAMPGSVSTDALNETGAFGAVGTLDDVITYIHLATVVSASEYKGASLRWWNAAWSLARELKLGRELPQTSASMASEQPNEGANDVDADGEDDDELPRSPGPITEEEREERRRIWWLCYIVDRHLALCYNRPLFLLDIECEGLLQPMDDTLWQAGEFYTGDSSIHITSPSGTQRTRRRGPNFECTGHSIFGYFLPLMTILGEIVDLYHAKNHPRFGIGFRSAREWDDHANEIARQLDAYGQSLRNFETEQIPPLPDDQNDQNMEGDQSSVNKPLEHNDIGTPSVHSVHSVHTASSHVSEANIQTQIVVAYGTHVMHVLHILLTGKWDPISLLDDNDLWISSQSFIDATGHAVSAAEAINHILEYDPGLEFMPFFFGVYLLQGSFLLLLIADKLQVEASPSVVKACETIVRAHEACVATLNTEYQRNFRKVMRSALAQVRGRIPEDFNEQQLKRREVLSLYRWTGDGTGLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6L6</accession>
    <name>A0A5N6K6L6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_001913</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6L6"/>
    <dbReference type="OrthoDB" id="242910at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071561">
        <property type="term" value="C:nucleus-vacuole junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000652">
        <property type="entry name" value="Related to VPS15-ser/thr protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045162">
        <property type="entry name" value="Vps15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583:SF0">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Phosphatase 2A Regulatory Subunit A helical" evidence="10">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="537"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="840"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="323"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="870"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="323"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="347"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="378"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="875"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="904"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8298162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="971" mass="107033" checksum="96636B91B759158C" modified="2020-04-22" version="1">MFFGTADSNDIILSHLNTYLNDRNWMLKCAFFETIVGVATFLGGTSLEEFILPLMVQALTDPEDFVVRSVLHSFADMAQLGLFQRSKIWEMVDVVSRFTMHPNIWIREAAANFISSATIFLSSADKLCIILPLIRPYLKTGLNDYSELAVLDALKTPLSKAVLDMSINWAIKSDRGIFWKVVHQLRTFSLNSGSFVPTISSKESGHHALQRISKNEEDEQWLSKLRNIGMSQDDEAKLLALREYIWRLATSKARESPTHPSYLNNVINLRSFNITPQTVMFDEQITEQPPRKINNGLEGSGEQHSIAEALLDASMTIDDSIAKRKRSAMNSHKSKTGLPITTNGLEPNSPTSSPALLSPTDASTSTTRKGSLVRPGSADTTGQMSDDGTASLLDATSINSGDTVRGIRHKSSAMTLMSRKGSGKGPPETGTTSTNAFGKVEGPFTQFTSQSLPITLTRGRNGAAKDEIRFRAAHTYSGNDPNILKMLDAMYVDNYPNDITEFGPMIAPSSRRRAISRNNNQAADKPWRPEGTLVATFAEHVGPIHHIAVAPDHVFFLTGGDDGCVKVWDTGRLERNIAHRSRQTHKHANNTKITALCFVEHTHSFVSCGSDGSINVVKVDCIQSGGVGRYGKLRILREYQLPKNEFAIWAEHFKLDTNSTLLIATNLSRVLAIDLRAMTILYTLVNPVHHGTPTCFCIDKKRSWLLLGTSHGVLDLWDLRFKVRLKAWGVPGATSIYRIRIHPTRGRGRWVCVAGGSGQGEITVWDVEKTQCREVYRAGSSREASKNYEPWPVDEDRPEGMLGRFAGALEPTANVSNYGIRAMITGTDAHDDNRDVKYGFVITGGSDRKIRFWDLSRVESSMVVSGLDTDELKPSYTSSHPTPILTLNNERVPRQNLTAPNAGARDRGKDGGKSDGGSKGSGKAPRSTVISLQGQKLLRAHLDSILDVALLESPYGMMVSVDRGGVIFVFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6L9</accession>
    <name>A0A5N6K6L9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Cellulase</fullName>
            <ecNumber evidence="3 9">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_001953</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 45 (cellulase K) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3 9"/>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6L9"/>
    <dbReference type="OrthoDB" id="10035502at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052288">
        <property type="entry name" value="GH45_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000334">
        <property type="entry name" value="Glyco_hydro_45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39730">
        <property type="entry name" value="ENDOGLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39730:SF1">
        <property type="entry name" value="ENDOGLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02015">
        <property type="entry name" value="Glyco_hydro_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01140">
        <property type="entry name" value="GLYCOSYL_HYDROL_F45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024962779" description="Cellulase" evidence="11">
        <location>
            <begin position="17"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolases family 45 active site" evidence="12">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="224"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="234"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS01140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8298213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="312" mass="31499" checksum="008C8755F5D8A07E" modified="2020-04-22" version="1">MKTLVALLPFFLQVNAQASGSGTTTRYWDCCKPSCAWSDKAVLASGSSPVGTCDIKDSPLSDPAATAASGCNGGTSYMCSDQSPWAVSDDLAYGYAAVNIAGGSEASWCCACYELTFTSTALAGKKMIVQATNTGGDLGSNQFDLAIPGGGVGIFNGCTAEFGAPSSGWGAQYGGVSSSSSCSSFPTALQPGCNFRFGWFEGADNPTVDFKQVECPAALTKSTGCKRADDSSMPAPDVSGSASASPAPASTSSSSSSAPVAPTSTKANYVVPISSPVSTHTSTTKTHKHSTTAAPHPIISAAPEDDDSCDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6M0</accession>
    <name>A0A5N6K6M0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_001919</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6M0"/>
    <dbReference type="OrthoDB" id="4074350at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47965">
        <property type="entry name" value="ASPARTYL PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47965:SF101">
        <property type="entry name" value="HYPOTHETICAL ASPARTYL PROTEASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="1"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="642"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="429"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8298169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="709" mass="77521" checksum="30EEE1EEEC421F13" modified="2020-04-22" version="1">MIKNSLDLKNYPFTSSTCPMSRGSIFNASQSSTWRSLYYWDHTASWNLGTGNALGWPPSGDFGLDHLAFGPDGPTIPKATVAMINDTEYWVGSFGLGASSGNFTYVTPKPLYEQLQDEGEISGAGYGYTAGAVYRQKGETLSLTLGGYDENRFIPHNVSFNLVGSAQSIPRLFIESISVISTNGSNTSIELASSKDGMKNTLIDSSTPFLWLPEEVCERFADALGLSYNETLNLYTFDENPNQHNNLSDPTTSTTFTFRLKDEPTVKDSVDIALPYAAFDLQLTYPYIPNTEYGTDEASKFYFPLARAANASQYTIGRAFLQEAYIITNYETNTFSIHQAVHVSDTLSNMSIVAFQGATRQSSHLSKGQRIGISIGVSIFGTGIILAGLYCYYIKYYKPKKHAHATTNSTSESEAGIHLQHVDSPPSMSPHTSEATSNNNYPVEINSEMAQTTEVGAQVPHQHLELAAAIPGELSTGIPVQPPAELEGNSSYGDFTFGHSSTEQSSSTVSLFSASLSGSIPSAAALAISSAEPSFEQSSAPATPARASVLSDNVSPMSQARMTGRMSPPPTYDLTHPSNHVFVRAIPSGSQSTSSFDQLTGAQASQPSNYAYAGTMPSGIQPPNPFDQTTQTCIEQINEWRRRDQERQAQEEELYRQALAREEEIREERFQASRRAHREQLERMEIEGIDVFKYRTEDVGDLKISSVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6R8</accession>
    <name>A0A5N6K6R8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_001958</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6R8"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000001">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000101">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000191">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF85">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="102"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="283"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8298219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="756" mass="84803" checksum="2F8579F5A745CAF6" modified="2020-04-22" version="1">MAGTTLAKDRRELKQQEAQDKATEDGAKVDLSAQWNDPMVDPDQRKFASDLRSVKQQAPSEVVPDWKRVTQNKNEPLGRRTDMSIKDQRESLPVYRFRSELIKAVHENQLLIVVGDTGSGKTTQLTQYLAEAGFANNGIIGCTQPRRVAAMSVAKRVAEEVGCELGQEVGYTIRFEDCTSPATKIKYMTDGMLQREVLMDPDLKRYSVIMLDEAHERTISTDVLFALLKKTIKRRPDLKIIVTSATLDADKFSAYFNECPIFSIPGRTFPVEVMYSREPESDYLDAALVTVMQIHLTEPPGDILLFLTGSEEIDTSCEILFERMKALGPSVPELIILPVYASLPTELQSKIFDPAPPGARKVVIATNIAETSITIDHIYYVIDPGFVKQNAYDPKLGMDSLIVTPISQAQAKQRAGRAGRTGPGKCFRLYTEAAFQSEMLPTSIPEIQRQNLSTTILMLKAMGINDLLHFDFMDPPPTNTMLTALEELYALSALDDEGLLTRLGRKMADFPMEPSLSKVLIAAVDLGCSDELLSIVAMISIPTIFYRPKEKQAQADQKKAKFHDPHGDHLTLLNVYNSWKQNKFASPWCFENFIQARSMKRAKDVRDQLLKIMERYKHPIVSCGRNTDKVRQALCSGFFRNSARKDPQEGYKTLIEGTPVYLHPSSALFGKQAEWVIYHTLVMTTKEYMHCTTSIDPKWLVSAAPSFFKVADAGKLSKRKKAERIQPLYNKFAAEDDWRLSAQKRQGRGGGGGTWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K737</accession>
    <name>A0A5N6K737_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_002066</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K737"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8298339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="236" mass="26795" checksum="A3A437FF8E45F94E" modified="2020-04-22" version="1">MSADFNDAYNSVFLRGSCANHIWEWPEDTRATVSPDKITLSAHMADFDRVTHIISFIDGDRSYFVSLFAEIETILALHAPKNEPLWRTLVGIRNTDHELILKYPRNFEVLMVRVEEQDGEAQKLFQDAILPIVRGREFFITDKGFAGVATPMIGNGDTIAIITGMGRAAILRDTDPKKIGLERRVDAGGNIYQRITGFAYVGCHHIDEFENLVKENTSDHRKHICVNRDLKESYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8P3</accession>
    <name>A0A5N6K8P3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SigF-like NTF2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_001246</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8P3"/>
    <dbReference type="OrthoDB" id="2344312at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057514">
        <property type="entry name" value="NTF2_SigF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35393">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35393:SF1">
        <property type="entry name" value="SNOAL-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24840">
        <property type="entry name" value="NTF2_SigF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="SigF-like NTF2-like" evidence="3">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8299137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="241" mass="27218" checksum="A2CF35C06A52234E" modified="2020-04-22" version="1">MDHPRTQIASIIYALCSGSPSAQKATLETYFTPDASFSHPLCSVPSFSSVELPVLGEIDSRWVLWCVYRWYKVLSPRVRVGIDGIDYNSETQTLFVQLHQVFHLFFVPFFAPTVNLTTVLHLTPSQRSSSSSDTAGSSESRRRTRYLIKHQEDLYQSTEVVKFFWPGGTQIIGFGRLIATLLCIVGAIAFAPITWMEEWGWFGNGKDVKERANTNEDEVNGVNGSKREKKRMVNGVSKKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8Q1</accession>
    <name>A0A5N6K8Q1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_001275</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8Q1"/>
    <dbReference type="OrthoDB" id="417877at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000153">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="12"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8299172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="443" mass="48818" checksum="367418D4386672BA" modified="2020-04-22" version="1">MSTSIRPEKPFHVAICGGGIGGLCMAIGLLKQNIPFTVYEAAPAFAEIGAGISFGPNSVRAMELIDPAVKHGFDNCATSNGSPEEREIWFNFRVGMAEEGWKDFKNDPPVKEGEFLTEVVAKDCGQASLHRAHFLDELVKLVPNENARFGKRVEKVEEKGSRLQMTFHDGTTAEADVVIGCDGLKSRTKHMVLGDDHEATAPVFSGKYAYRGLIPMEKAVAAVGESLARNSQMYVGHKGHLLTFPIEKGAVMNVVAFRTKRDGKWDNEKWVIPVRKSDMLEDFEGWGKDVKHILSLLEKPDIWALFDSIPAPTFYKGRVVLLGDAAHASTPHQGAGAGQAIEDAFILSNLLGDCTELEDIDRALKAYDEVRRPRSQKVVTTSREAAALYEFENEEILEGENGVDIDDLKQRLRERCQWIWDEDLGAQLETARGIARGGGNAHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8Q2</accession>
    <name>A0A5N6K8Q2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_001004</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8Q2"/>
    <dbReference type="OrthoDB" id="10054429at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF13">
        <property type="entry name" value="THIAMINE TRANSPORTER THI9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="478"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="515"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8298841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="556" mass="60362" checksum="64A700FF5EBCD8A0" modified="2020-04-22" version="1">MAHEGEDVKNATIEARDDAQLETLGYKPVLHRTYTLIENFSTSFAALYFVGGVRVTYTTGIASGGPLAYWTSYIVTCVFTFITAAVIAEVCSASPSAGSIYLWAAEAGGPKYGRLLGFVVAWWSTTAWMTFCASNTQGAVNYMLSEIVVFNVDFPTDTSDIKFRAVQWICTEVLLALAAIVNFLPPRLFKYIFWLSSFLVMLDFVLNLIWLPIGAARTIGFRTAEEAFMTTYNGTGAPAGWNWCLSYLATAGILIGFDASGHVAEETKNASITAARGIFWSVIVSGIGGFATIILFLFCTPDPDTLFSYGSPQPFVPLYAVVLGQGGHVFMNIIAVVALWFNTAIAIVAASRLVFAVARDGVLPFSGWVSRVSAEGQPRNAVLVIWGCASLVTCTILPSAVAFTSLISAAGVPSAAAYGLISFGRFFLTPNTFPQPRWSLGKWSRPFQFISIFWNGWVVAILFSPYEFPVTGATLNYAPIIMAGVTILALISWWFTPVGSWLPRERISHFVESEGAPAEGLRQEDDDQVRTPELEGDASPATISENGELLDRATAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8Q3</accession>
    <name>A0A5N6K8Q3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8Q3"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="77" mass="8949" checksum="1FD211A9021CC245" modified="2020-04-22" version="1">MLLSQSKIPLETAALRILRNYLRPRDCMIDQYFVFSIPPIQGNFFNKLSHHPILTNIRFLSSARSFNISRSAHHNGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8Q5</accession>
    <name>A0A5N6K8Q5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8Q5"/>
    <dbReference type="OrthoDB" id="5428259at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="303" mass="33779" checksum="5913F9C358A1A224" modified="2020-04-22" version="1">MSKNHTNIPLHCSICPKNPQFSDVSHLLTHTSSKAHLSNYFKLKIRAASELTAKVQLDNFEDWYDTYDLERLLSERLASKDQKKAAKDKKIRNSKAMLPGRSKIKKEGNNTLDDESNLAPMFRAPVPRMHLWPTTTNTNIDNNTSTSNSDMGSEWDHNAMYSTPTSSRHIPGYTLQKTPSAVGTASVTTNLTTPMKEEGADAEIIEKLSDSAKLKGVLWPGMDLFDSATAEMKRMRNQRKDGSILELMMAASAEVQPTEVSYHPDGAFRTARNIFGPLSTETNERSHAKETQNSQDGVGRCQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8V3</accession>
    <name>A0A5N6K8V3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8V3"/>
    <dbReference type="OrthoDB" id="5213862at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="577"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="725" mass="79009" checksum="087CD5F14A01BD49" modified="2020-04-22" version="1">MVPLSEVSTHLESRQPEVEPAPLRIIKRSQTVTSRPSGYEFGSADEWGMFESTFENESEGSPPVAASRPLGPLTIHKTRRGRGSILDDSLSVDIVNIERKCSTPKVDDRDYRGPLEDDLFHTSVATHSSSQDTSTGKFLRTYSRLGNPGNEAKKHSIRSSDLQSNILGTPKTDGSPIIPKRKPSKSKYSLLRAFGGRRSEDSEPKHTLGRSGSSASTRSMKSHSTLLRKLSHRKSTASTIQSDASSVPSSLGAVELSHLFDSDGQDIINARINSGASSYYGGTVMMPSPSTPILTPMISSSRDDNCVLCPQISVTPESASVNAGVCTLWAAVEITGVLRSADGASPLNDASRTYSTQSLTPRCLDLRRYGSLHNIAVEFQPGPDCIIVDQPEDTFQSKTLRVSETHLMLVKIRLNEVKVSVSQEKDKSSDELIENINEILGDTTTQYLTVKLNYRHSAFLNLRQQAAGGDFRVLPQHTLLETKATATIKRHNPASAWSPRNSGALNSAVGKIGKFAADTLAYLDPTNNLLSHSFSMTAISNLNARGSPVSKRPSSPYDHPLDLVDGEMDPARKIWSQMRRTSRPARKHPRASISDGNYFSADQDTLFESTPRHRSSSRGTNLFLFEPPEASPPDTSLELTPKARQSRDSREKSPGTTTNDNRHHLMELALKNKRSVGQETLRSMVPSTYSGKGTGFGNRQGGVMGAVAGVGLAGRNWGQWLPWGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8V6</accession>
    <name>A0A5N6K8V6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8V6"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="121" mass="14108" checksum="FFBB4E2168466799" modified="2020-04-22" version="1">MLIGPLDYLLLSYTNKQLSTTFIWNSDDDFYLSKKKKEKKKKKKLSNNLPVLSSSHFLILINQQFTQILQPQKFIHYPSQSSILLLPATTYTSTQFVPQRNPHPTNYLFTPETDHSFKVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K909</accession>
    <name>A0A5N6K909_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_001362</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K909"/>
    <dbReference type="OrthoDB" id="2320933at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18026">
        <property type="entry name" value="DEXHc_POLQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.20:FF:000005">
        <property type="entry name" value="DNA-directed DNA polymerase theta, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000968">
        <property type="entry name" value="Helicase and polymerase-containing protein TEBICHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057220">
        <property type="entry name" value="DUF7898"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046931">
        <property type="entry name" value="HTH_61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048960">
        <property type="entry name" value="POLQ-like_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF6">
        <property type="entry name" value="DNA-DIRECTED DNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25453">
        <property type="entry name" value="DUF7898"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20470">
        <property type="entry name" value="HTH_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21099">
        <property type="entry name" value="POLQ_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="150"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="405"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8299282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="929" mass="103142" checksum="CC5A2576B33526CB" modified="2020-04-22" version="1">MRRLNTTRSGIYHKTTIDATRVASTTVSRVAVKRTFDELNDAENPQGASSPSDHGHLEVGASKKIDFSRPTLNDKSHGALKASEIDDITVHNYSEYSQRRQLALTPTPTLNPLLDLAHPAYQLPNQLIENFTALGIKSIYPWQSECLLRSGALAGERNLVYTAPTGGGKSLVADVLMLKKIIQNPEKKALLVLPYVALVQEKLRWLRKVVEGISKETPSRESKWPSMWRDRGDEDTIRVTGFYGGSKSKSTWADMDIAVCTIEKANSLVNAAIDECSIGNLGVVVMDEIHFINDESRGYILELMATKLLSLEQDVQIVGMSATLDNANLLAKWLNNAKFYISNYRAVPVEEHLVFENAIYPASSSTTFYKTASQLNLQTGNNSTDSLPDPHRRIQTSQHKELSNPLLNSVVALANETARSGYGVLVFCSSRLGCERDAIVISQVLPPPDAVNPTLMNRRYDLLNDLRNTSSGLDHVLERTVPMDAGLTTEERELVAAAYDEGILKVMVATCSLAAGINLPARRVILHGARMGSDLVGPSMLRQMRGRAGRKGKDEIGETYLCCQKSDLEAVAELLEAEIPSVESCLVPGKRGIKRALLEVIATKLATSRESIDDYVKKTLLYHTIDKGELTSMVAATLEDLLENKLIEQTQLYSYEATRLGQAVVASSLAPEDGLFVHKELRKSLEAFVLDGEMHVLYTFTPVQATQGNINWQVFRKEVDMLDESNLRVLGFVGLKPLLINKMAQGGSMKESTPEEIEITRVYKRFYTALQLRDLCNEMPVHAVARKYDLPRGTIQNLAQTCHGFAAGMIKFCEKMDWGALAAVLDHFSDRLKAGAKSDLLALAEITFIKSRTARIFWDNGYKTVGAIAGADSKELIPVLLMAQPRKLRLALDDEEKYHARLLAKATKIVESANRIWERQMQQEIYEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K910</accession>
    <name>A0A5N6K910_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA mismatch repair proteins mutS family domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_001359</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K910"/>
    <dbReference type="OrthoDB" id="2534523at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043504">
        <property type="term" value="P:mitochondrial DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000036">
        <property type="entry name" value="DNA mismatch repair protein Msh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.110:FF:000022">
        <property type="entry name" value="DNA mismatch repair protein Msh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.10:FF:000010">
        <property type="entry name" value="DNA mismatch repair protein Msh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF34">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="8">
        <location>
            <begin position="967"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="115"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8299279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1078" mass="121660" checksum="03ED1E9A863584E4" modified="2020-04-22" version="1">MSFLNARNFRNFRMHNNAFVSFHSLNTRQRIASSNCSSHIALRSAINLQPQLFHRGKKTKSSFNFNDLPHKLDLSPLEPLSLERSIVKDKSPDRVSLKFFEDVQDLLQEPEPAATELEELPNSTSSQDFEEVSKKAKPSRRARKTESLPQGLITLDSESSDVQESQDTSSPSAGGKKVKKTKSYDELELHQGLLPLEPLQIEHEPPPYPTVIMQARNNMLKFENCVVVTRVGGFYELYFEHADEFGPLLGLKVTHKKTNAGPVSMAGFPFHQLDRYLKILVQDLNRYVAISEEFPNDISDKVKSGGLMHDRRVSRIVTPGTLIDEGFMDPLSNNYVLAIHVQHDSQTDIIEHERNHNAIGLAWLDLSTGHFFTQKSSLSELPSFLARIAPREIVLDEEVHSLKDHEMFTILTDEHHIITYAKLPEVRPISEWTHMLESPVSSSSANAFTEEEISAGSCLLHYVETRLQSTNMKLQPPVRQLNVMGIDKNTMRALEIKKTIKEDNFSGSLLHTIRRTVTKGGARLLENWLASPSTSVEVINSRLDLVTYMLEDEFLRDRATTLLKRSHDSHRLLQKFAFGRGDGDDLLDLASTIYATRDLASILDVQKDTPESCIQALLARIHLKGPMKLAQAITDTIDEEGLDQQHRIEEGESGEMQALAEAIVASEGTTEETSTFRKNFRKKQPNSLRDYYNQENEAWIMKPDATPTLKRLHKKLSSLSDQKTALAASLCDRLGATTLTLRFTPGLGHICHIKGKDINLNMPEARTISSSRSTRSLHHPEWSFLGQEIDQCRIHIRAEEQRIFYKLRELAITNLVKLRRNAAVLDEIDIACSFAMLAYERGWTRPILNTSSAHKIIGGRHPTVETGLEEEGRSFISNDCLVGDVHRVYLISGPNMAGKSTFLRQNALITILAQVGSYVPAEYAELGIVDHIFSRVGSADNLYRDQSTFMVEMLESAAILKNATSRSFVIMDEIGRGTTPKDGIAVAFACLHHLYHVNKCRALFATHFHALVDLIEKKNMDAVGFYCTDVEEDGSADGVFRLVIFTSHFIFIPHAHALAYYHHVFFCILSDIRRIHIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K921</accession>
    <name>A0A5N6K921_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K921"/>
    <dbReference type="OrthoDB" id="1937934at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="74" mass="7689" checksum="C5B2C5CF07E1F330" modified="2020-04-22" version="1">MSASPPTAPTQSTKRPLEDPSSPSAPSDQPDAKRPALDKIVKGDDDDTEKEPAVAETSLPVHVVPNGDAKNATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K924</accession>
    <name>A0A5N6K924_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_001108</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K924"/>
    <dbReference type="OrthoDB" id="421009at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15844">
        <property type="entry name" value="SNARE_syntaxin5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF3">
        <property type="entry name" value="SYNTAXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="273"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="112"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="178"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8298961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="365" mass="40243" checksum="2FC64D7DB9AACCAD" modified="2020-04-22" version="1">MHTIPQYLLISSSYISLIHNKHTPASTFRKSNTTTIRAPVNQRNVTSNLEPRTSNLANKETHPQTSIIQSGSSEAITSLRFTKGRSKWRCKRTWTTQKIGICEKGRRDWERDNRHHGEVTKAGRIGQTQNPLRRPPGGNQRTHLHHQTRPLLPQPTNLGSPKPHASPAPQSRPGGANTTKTSSSCSKASSPTSPPTSKTCSKSAPRTSRPRAPAPKIFVSSVSSHVQPNISQSASPLYSTPARGSPGPGQDLLSLNPVGDQQLLMMEEAQPQNEYIHQRGEAIEAIERTISELGGIFGQLATMVSEQSEMIQRIDANTEDVVDNVEGAQRELLKYWSSVSGNRWLIAKMFGVLMIFFLLWVLIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K928</accession>
    <name>A0A5N6K928_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small-subunit processome Utp12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_001374</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K928"/>
    <dbReference type="OrthoDB" id="407922at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051570">
        <property type="entry name" value="TBC1_cilium_biogenesis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN 3 WDR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="4">
        <location>
            <begin position="51"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8299298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="186" mass="20871" checksum="52969692649F4441" modified="2020-04-22" version="1">MAGEKIVEALEIGTADLELMAEYEIAKASNPNTAPPARNLLFMALGNISAERHVLNTFQKIKAAALHDALLVLPFSTLPMLFTFLNIFATKEMNIPLTCRILFFMLKTHHKQIVASKTMRTMLDGIRESLRKSLKRQKDEMGFNLAALKIVGERVKDLGTKDYVDEETWEEGDGSSKKKRGFVQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K972</accession>
    <name>A0A5N6K972_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA cytosine-C(5)-methyltransferase NSUN2-like PUA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K972"/>
    <dbReference type="OrthoDB" id="6093671at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057286">
        <property type="entry name" value="PUA_NSUN2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25378">
        <property type="entry name" value="PUA_NSUN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA cytosine-C(5)-methyltransferase NSUN2-like PUA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8299342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="169" mass="17971" checksum="A4FD2B4E7F59079B" modified="2020-04-22" version="1">MGCCVLRIEPGEGEDAFTERMVLPLWRSLHSLNLMLAKEDRSAMLLRIFNDTTPLVNNSVGAQREAELKKEGAAKQEVAPGFKVENGEIKVDVDGGLEGASASVQDNQRDGDVQIKEGPYSTLVAGVDQVANNGTDVKAEIIEKDEETGGAEEQLDGMGGIEGQQGGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K974</accession>
    <name>A0A5N6K974_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K974"/>
    <dbReference type="OrthoDB" id="5428038at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="756" mass="86220" checksum="8BE29EA12DB09D0E" modified="2020-04-22" version="1">MESRRRLGRRRMAHVTEMTQAPMYDPGAMWCSSWGPEKVESQWKAPTPRITEQSNHFSILPSWLTNFSTMSGHPLADSTETTSTGNSIEKCHDVLQQERCIKDHFDDFEMAIRAHRQECNDMISHQETGEKKQRLRKRIYGSVKAMKLCLSFSERLEHSLTLGLVSSDLLSSTLQAITDVLIEFSSGCYSKTEDHTKKSIKMRGRSRGTRINVTTQLLVFYTRVWKGIVSCKVLKPADFESEAMGEYLSLLARLPSTKKTQLLVSKILPSLSVSQLLSNTDAILSLLNKWTLSWLKKPKRSIKREESLTKAEESVAATGRSINHLSMLVWSNRDNSTPEAIQHIRDILIRTSTELSAAKREVFAAENIIIPYSHSVHKLSTTLATLPGEVISTLVGAHSELISSSSFFDQKSVLGFQDYLAQSHRIRFNWLCALSKSEKIDDTMFMGVFKSLQLQDLGHFNHAIKQYTLTQRQTAEIILNRWTSQGVIRNGNTIIDTFKLKTIHSPWPYGWLLSTLERHGQLSDEKIRDLLDFLLDTREFRQIDAVLKQSKMFNMQVKTSILADLVNNMTSVNLRAAYNIYMQQCLGKVEPEACAPLIASMIYQRGSKRIWAALDAPIYAAMPRWKRKPPSRKVISQARIELVHEMAKAFAHSKVHNPRKALRNVTQCLHYLRAHDVQLTSEISTLITQVGITTDVKNNKWGRTERVRWVLKVIEVAEGPEVADVVRKAVVRWREKLTARLESRKARSQSLESLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAB9</accession>
    <name>A0A5N6KAB9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAB9"/>
    <dbReference type="OrthoDB" id="5428901at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021840">
        <property type="entry name" value="DUF3433"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37544:SF3">
        <property type="entry name" value="SPRAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37544">
        <property type="entry name" value="SPRAY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11915">
        <property type="entry name" value="DUF3433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="514"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="565"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="647"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="677" mass="73836" checksum="D42550FB6D23693B" modified="2020-04-22" version="1">MRPFRRIHLLPSKNKYYRPHATRTESLLILLIITLLIIGLLEYSCHVIPQHSGFGSTAEEFVNMTRSKLEARGGNEYRRAAAEPSLSSATTSTPLVPVLVPSDSTYSTPRTSPAGFTIDSTTVPLTAAGSSYLTPKETTTLPESTLFIATHLTPSSLQSVEVTDPTPETSTSVRATYLTPGSVAKTDGTYMTPDPTIPLPSTSAPGMVIPSSKTTTPSPIVLIPTVSITSDYTSTITVPSSSISNAGPPPVVVPVTSNYISTITAPPPSNPNNAPSPIVVPITSDYISTITIFNPTASNKRLSSNEPETKVNTPIFKSDQKVSDATSVKLITLTSSVIDSDGSFAELTTITSSSLVHLFPSTTNMPQNEPTTSNPTSALIETNPADSSMLVIVSTFRSVYESTIFPTSSDIIVDKPVATSANSSGTFIYHSNGNVTAPDQITYRQYLIASFLPLFLAIFYAIPWRIMENTVRYMEPFYQFRPFSHYTESQAIHLDYESSSTFIIPFKSISRKHFTMFASSLISIIILVIAPIASQVMIIFESNYCEGTGLTTCDSWGIYPSFARMLEGLLSAIVVLILFLIFAGLRRDTGVYSEPLSLIGLAVIYIKTPLSFQAADNNSGLREDRSRIAVQNYTSLLAHEAETTQATQSSTLLRSKRRERYEKDKSYQRYGTKSRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAG1</accession>
    <name>A0A5N6KAG1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor TFIID subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">TBP-associated factor 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_000341</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAG1"/>
    <dbReference type="OrthoDB" id="21060at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007900">
        <property type="entry name" value="TAF4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05236">
        <property type="entry name" value="TAF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID component TAF4 C-terminal" evidence="10">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8300111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="128" mass="13732" checksum="8CF48A8691B8E672" modified="2020-04-22" version="1">MKRKAEAKTSEAASHAAANVTTGQFLGGRNVFGKKKQYSWMTAGSGSGTSTPGKIMAQGLSASASSPAANPGPEKLTIDGVRRLGTWREDGVKGRKIQLRDWIMVLEDDGREKRALQKAYAVDDDHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCD3</accession>
    <name>A0A5N6KCD3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCD3"/>
    <dbReference type="OrthoDB" id="5970at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="26553" checksum="7897AA7C5F810DE0" modified="2020-04-22" version="1">MSRGGTTLYVTGFGAGIRARDLAYEFERYGRLVRCDIPAPRTAASRLRFAFVELNGPAHLPRRLGDSILVRTVQAVVMVAGTAAGNVVDAVLLVVVQTHPDVAVATTLRVRTTEIAGTATTTDETATELIAHVAPMIGTAILRMNVMMSENPVPMEMTGKLPWILLHQRMMNWTPPSKQVLLRIRLAHGRKKFIIRFPETFRLEPGPGLATPTKLKPPSRSAACDCGHSFSWVVSIKNSKLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCD4</accession>
    <name>A0A5N6KCD4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCD4"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="86" mass="9864" checksum="76128442CFEE881A" modified="2020-04-22" version="1">MRPVSGVSLNHKILNPPFFKEQNLTLPTLNSQRSRNPQNLSKYLRRLSMACDNQKNGDNKVKAFQSLRLFSRDLLLPACGRSSRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCD8</accession>
    <name>A0A5N6KCD8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCD8"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13969">
        <property type="entry name" value="ADCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045307">
        <property type="entry name" value="ADCK1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF19">
        <property type="entry name" value="AARF DOMAIN-CONTAINING PROTEIN KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="80"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8301099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="487" mass="55889" checksum="13755D44FBD9FA6A" modified="2020-04-22" version="1">MPMKRWRGQGECYRVTLNHNEKIGNEAEKDKMLKDCHQRCADRTLRVLEKNGSIFIKLGQHLSAMNYLLPLEWTTTFIPLQDKCPVSSIESIENMFRMDTGEQLSDYFSEFAPEPIGAASLAQVHLATVKETGQKVAVKVQHPNLAEWAALDLALTAFTFSTLKKFFPEYDLEWLSSEMEASLPIELDFTEEGKNALRAKDYFSRIPELPLVIPDVLWAKKRILVMENVAGHRLDDLDFLDSNGIDRDEVSATLARIFNEMIFGNGAPLHCDPHGGNLAIRKNDTRRGANFDVILYDHGLYRDIPLDLRRSYAKLWLAVIDANEPRMRKYSKEVAGVTDEQFPLFASAITGRDYTILTKDVSLKRSEEEKKNINDALGEGMLQQLVQMLGQVPRIILLILKTNDLTRSLDENLHTRQGPVRTFLILARYCSRTVFQEQIEEIRERGSLLWPTNGFRLLLAWLGYVRVELKLETFEVWLRVKRLMGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCE5</accession>
    <name>A0A5N6KCE5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCE5"/>
    <dbReference type="OrthoDB" id="204164at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF4">
        <property type="entry name" value="N-GLYCOSYL-TRANSFERASE (AFU_ORTHOLOGUE AFUA_4G06870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8301110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="125" mass="14005" checksum="5232839F4C9CA819" modified="2020-04-22" version="1">MASKLDKDTVIVEGKYQNPDNLRPDANDSSGYKEFDTGRTYMALMGNWRENKDEEVKLDGIGGVNIIVKADVHRSGINFPAYAFENQAETEGFAKMAKRAGYEVIGLPNYVVWHMDTEEKPGNNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCE6</accession>
    <name>A0A5N6KCE6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCE6"/>
    <dbReference type="OrthoDB" id="5970at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="6"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8301088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="242" mass="26397" checksum="29427C6510392407" modified="2020-04-22" version="1">MSRGGTTLYVTGFGAGIRARDLAYEFERYGRLVRCDIPAPRTAASRLFAFVELNGPAHLPRRLGDSILVRTVQAVVMVAGTAAGNVVDAVLLVVVQTHPDVAVATTLRVRTTEIAGTATTTDETATELIAHVAPMIGTAILRMNVMMSENPVPMEMTGKLPWILLHQRMMNWTPPSKQVLLRIRLAHGRKKFIIRFPETFRLEPGPGLATPTKLKPPSRSAACDCGHSFSWVVSIKNSKLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCK8</accession>
    <name>A0A5N6KCK8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Complex III subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_003013</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCRB/QCR7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCK8"/>
    <dbReference type="OrthoDB" id="425749at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1090.10:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1090.10">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003197">
        <property type="entry name" value="QCR7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036544">
        <property type="entry name" value="QCR7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02271">
        <property type="entry name" value="UCR_14kD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81524">
        <property type="entry name" value="14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8301105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="152" mass="17548" checksum="7AE0FE33236BB677" modified="2020-04-22" version="1">MSAPSLASWIVKKPGLLKIMQPLASWYTNAAGYRQLGLRADDLLPEESEEVLLALKRLPQKEAYDRVFRLRRAVQCSVQHQLLPKDQHTKPEEDYAYLSPIIAEIEAEAKERADLECWICIFGSGEWDLRVWGESTEKRCSVLYNVDHQFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KEH0</accession>
    <name>A0A5N6KEH0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1748-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005573</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KEH0"/>
    <dbReference type="OrthoDB" id="16824at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013726">
        <property type="entry name" value="Mitofissin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075:SF1">
        <property type="entry name" value="DUF1748-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08520">
        <property type="entry name" value="Mitofissin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8056" checksum="C98B1621437AEF4F" modified="2020-04-22" version="1">MLGKLTHYAFDAVLLSAFLAGMKRSTGLTLKKDLTENKELNGWIEKYLGVGEWVMDQSVAIAGSSSFFERKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KEH2</accession>
    <name>A0A5N6KEH2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_005626</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KEH2"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051965">
        <property type="entry name" value="ChromReg_NeuronalGeneExpr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040:SF3">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="118"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="118"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="62"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="342"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="506"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="366"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="461"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="510"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="521"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8302180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="569" mass="62670" checksum="E1DACF303C1EBDAD" modified="2020-04-22" version="1">MTALSEIFEELGIRHYLDNFIEQGFDSWDTILDIKESDFDALGVKLGHRRKLQRRIANTRGLSSDRALASPTGSTAGEINGEEQPKLGGVRDAKEGLSGPHGAKRKYRRHPKTDENAPERPPSAYVIFSNKMREDLKGRNLSFTEIAKLVGEHWQNLLPSEKEPYEQSAYAAKERYNNELAEYKKTQSFKDYSQYLTDFKQKQNQQLATEMDVAKRPKLEATANSATGSNVSSQTGGNPTGAEFPVGRMRVNSTASSSSQWHSSTPPSSVIMTPMQTLPALTNVPKVPVLQGRLNPASPVDMPKVLPGYRESILGPGGSPIDPAKVLPGYRESILVPGAQHWREDHRDEGGNLQQIPRPSIERRISQSGSPSSTQDHLNMNGSTHHRRNRQGNLNPPPSLTSESTVQSNGSAPSNSSMYFPPRTPLEPDLNRALPIPPLYPQKSGSYDSPLQFLAGPPSLSPQNPLPGTQQSPNVNSIKDFPTTMPPIRRYSEVAQTISNVMGSVIGRPDMTRSEKRTTDPSHPQSMANPHHQSTSNYIMAADELDLDPINALLRAGEIVNRTSREGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KF03</accession>
    <name>A0A5N6KF03_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_005699</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KF03"/>
    <dbReference type="OrthoDB" id="161814at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF115">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8302258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="149" mass="17131" checksum="996A5D0CA8AD6F2C" modified="2020-04-22" version="1">MDHSMHGMGMDMGGDRCNMNMLFTWDTTNLCIIFRWWHIRSTFSLLISLLGVIAITVGYEAIRSLTRRYETWVEKQQGSITRRNQEEVGQRAHVVKAALYAFQYFYAFMLMLLFMTYNGWVMIAVGVGAFVGFLLFGKDTSASKETACH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGL7</accession>
    <name>A0A5N6KGL7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGL7"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="68" mass="8103" checksum="9CCF811AA51BDD39" modified="2020-04-22" version="1">MCNLYLSENFLHIITGKPLRQRRPSQHYHHNFFDPDYSRYWPTRNTPKTISLPNSHNAIFNAGIHIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGL8</accession>
    <name>A0A5N6KGL8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGL8"/>
    <dbReference type="OrthoDB" id="63113at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="253" mass="27749" checksum="ED3133F69EB0421D" modified="2020-04-22" version="1">MPQWGRPSGAKGSRRRRQWEQEQGYWQQSRVEELDSEGDTDTQGAGLHLGEKRFASDPLHFTGIDISSNTRPRRGYSYDRAEQSSDSDSEYSDYQEGGDRQVALRGSNEEAVVQGALARIRRAQEKGRQDVKLTQEELDALERRRIRMQAAAAAKASKKGSSGSGAEKKRRSERKTVDIASLLDPKPASDPKKRKSKRKSGSSHSTAAGPGIIVDGPDGPSYTPIGGYYPSDRGSSRSRSSARHGGNSPPGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGM1</accession>
    <name>A0A5N6KGM1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGM1"/>
    <dbReference type="OrthoDB" id="942095at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="498" mass="54770" checksum="7C07BC23003A5FE7" modified="2020-04-22" version="1">MRSAGVDIDQVIENVLAQRCDALAGWWALLLEKEERKQVRKERKRREREAENRSSRRLSAASSRLEKMTPILTGVDEEGQPLKMSDPPRSRGRKERRSAHYPDLILTDLPGLPEHSQFSSPDVHTPPPPLEKDSIRSTSSSRHRRPIPPPKEGTLRSARSRGSTLQLVTSNHDFLHPSTNGIVKPPQRRKHQHPIINQLAHWKHWLLDSARRARSPGKKTKASRSTPDLREKAADGSSSPKEPSPRPVTSKSPTMTRAPVPHIGGQPPISRMYTTSSTKRHSLSPSPVTPRSTFQRRPSSGLRGRKSTSSSVSSVRSIMHQHTHSKASSTSSNGSGSKISLPTRSPHHSVKVLPATPTLSSFPSNIRVVRQTPLSSFNEGVSWGGNNSAFGAPLVFAKRKKNVFKGPSLNTASSAASGSGLGHTRTGSHSRSTSIAGRRSGEIIEEEDEEEIEEVDVFTPIIGPGETEEMVFTPNDMLRLDDTIEESDREKTPTNGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGS7</accession>
    <name>A0A5N6KGS7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Reactive mitochondrial oxygen species modulator 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_006287</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGS7"/>
    <dbReference type="OrthoDB" id="5409308at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018450">
        <property type="entry name" value="Romo1/Mgr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525:SF1">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10247">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01378">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8302976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12004" checksum="BE5E82525A874763" modified="2020-04-22" version="1">MPPVPQSQGHPGGQTVWNKLQMGAMMGGTVGAILGFMYGTLTIIKFGPGPNGVWRTLRTYMLTSGSTFGFFMAIGSTIRSDSIASPETLAAFGRASQRSLIMNRPYRPSRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KH44</accession>
    <name>A0A5N6KH44_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8303022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KH44"/>
    <dbReference type="OrthoDB" id="4760831at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="242" mass="28103" checksum="263D772439C4D2AB" modified="2020-04-22" version="1">MDSSHSIHNVPLTSHPILQSVFRPSTYHQHQDQHAPISAVSTDSNPKHSFTFTTAPQGPTSSHQSPPFFAAELPAFPHSLSLTRSDSLSHPPRYQHQHHHQHPQFDHPFDQLDHSFDHSLDHSFDQLDHSLDQLDHPFDQQDSRDRREGQLSSQASYLTQPLPSPSPSETETLLKNLILPELETLEKGERARREEEERSKREWEREFGILSEDYYIMRSTGRHDKKFEEIEEGITEQEQEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIP2</accession>
    <name>A0A5N6KIP2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIP2"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8303538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="184" mass="21188" checksum="58C6329BB8441767" modified="2020-04-22" version="1">METQKLKAKEEGDKEKERLGKGLLAKDREIRALQTGMGVKRQEIAKLERNGDSLRNNVERMEKERAALCKKVECEEKQNKELNDTMLSQEIEIQGLRRKLVSKTEIAKEMETKVKELKTKVGKWKAHTTTLLSCLREEEQRSWSKLPITGSLYHYLGSWYSSDKSVVTATEALKGFLRSEGIFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIR7</accession>
    <name>A0A5N6KIR7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIR7"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="322" mass="36040" checksum="B7948A2AC4E10F97" modified="2020-04-22" version="1">MHGRLAKNDETTHSFHVRNQIVMDTLTRVLQMNHDMSRMMLSLTSPESPLHRDVIAMQGDIQRQIETVRGMEDPNEPPFSNTRPYFSNLTLDNPPSPRQVPQDDTRRSSFLGVPPRQNFHRPPVPSNLSFSSRRGYGSIGGAGTAQPSPNSLRSQVPPPAPQPHPLANVSSPPTNLPRRHTSADIRNVVGWQATSSPFASGQSSSHYPSSPKRTATQMMSEDQRIRDSFSLYSLTGASQGHNMSRPTTPPYTNGNTAEHLNSWSWAGSRDRGPSSLFRDNSGPPTRRGSMAHILNPAETAEREEEHEEEMLREEDRKRKRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJ10</accession>
    <name>A0A5N6KJ10_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJ10"/>
    <dbReference type="OrthoDB" id="442677at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="107" mass="11490" checksum="5C8E8A95CC09DD1C" modified="2020-04-22" version="1">MGKRSRTESNNGENKPNPKEGSGKLFIAEDKAVDPTLALLFASSAGPVQAPPKSRYQEAPPPRRTNVESQDVGSSDGSDEDDAEDDEMGEGGDDLRRMRSQISKGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJ27</accession>
    <name>A0A5N6KJ27_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJ27"/>
    <dbReference type="OrthoDB" id="416093at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF589">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="280" mass="30314" checksum="215C8D6D8C96FF21" modified="2020-04-22" version="1">MEGEPIRKPISVEATLMYAFLKADLDFISAQARKPSSDDINTDSPLNADEILGEPARHYSPHRIGGPTRFMGGSTASIAMISTPTPTPFWHPASPSTLIVAHVGDTRIILCDTLTGVAKPVTTNHHPSSPIEGGRLRRYAATFVTDSFGEERMSGLANTRAFGDMRSKRIGVSAEPEIRRVEIAPAEYSFLVLVSDGVSGTLTDQEIVDVVKEAKTPEQGARDVVSFATEVSKEGDNATCLVVRLGGWERRIEGGVGSMGTKEVRDYKKGEAMDPRRART</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJ29</accession>
    <name>A0A5N6KJ29_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PLAC8-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJ29"/>
    <dbReference type="OrthoDB" id="1045822at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="15268" checksum="16E14C5845642C29" modified="2020-04-22" version="1">MPTAYKNSFWACCTPFDLCLKACCCPCFVSGRNHHRIEHGNDDDYSTCNGWCCGWYGLAAVGGFSFVLQMLDRQKMQKQHDLEGNACTGCMGSCCCACCELMQTSKELDYILLEKNTSTKGYQPEPGMVAGPQPVAYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJ37</accession>
    <name>A0A5N6KJ37_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 14">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="10 14">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">EYC80_004685</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10 14">
            <text>6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10 14">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10 14">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="10 14"/>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJ37"/>
    <dbReference type="OrthoDB" id="434986at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009051">
        <property type="term" value="P:pentose-phosphate shunt, oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000002">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.320:FF:000002">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000007">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.320">
        <property type="entry name" value="6-Phosphogluconate Dehydrogenase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006184">
        <property type="entry name" value="6PGdom_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006765">
        <property type="entry name" value="PRK09287.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00461">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="5 10 14" id="KW-0521">NADP</keyword>
    <keyword evidence="6 10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 10 14" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase C-terminal" evidence="15">
        <location>
            <begin position="181"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="35"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="77"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12">
        <location>
            <begin position="131"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12">
        <location>
            <begin position="188"/>
            <end position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAB8303239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="492" mass="54363" checksum="743F99EBC59BD8E4" modified="2020-04-22" version="1">MSQPTGDFGLIGLAVMGQNIILNAADHGFNVIAFNRTTSKVDRFLENEAKGKSIEGAHSIEEFCAKLKKPRRIMLLVMAGKPVDDFIETILPHIEEGDIIIDGGNSHFPDTNRRTKYLAAKGIRFVGSGVSGGEEGARYGPSLMPGGNEEAWPYIKDVFQSIAAKSDGEACCEWVGDEGAGHYVKMVHNGIEYGDMQLICEAYDIMKRGLGMQDKEIGDVFAEWNKGVLDSFLVEITRDIMYFNDDDGTPLLEKILDSAGQKGTGKWTAINALDLGMPVTLIAESVLSRCLSSLKAERTRASNVLSYVGRSNKFEGDKKQFLADLEQALYASKIISYAQGFMLMQEAAKEFKWKLNKPSIALMWRGGCIIRSVFLKDITAAYRADDNLENLLFSDFFNKAIHKAQPGWRDVVSKAALMGIPTPAFSTALSWFDGYRTKDLPANLLQAQRDYFGAHTFKIKPEHASEKYPEGKDIHVNWTGRGGNVSASTYQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKT3</accession>
    <name>A0A5N6KKT3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Muscle-derived protein (Neurite-outgrowth-promoting)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_003716</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the taxilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKT3"/>
    <dbReference type="OrthoDB" id="425555at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026183">
        <property type="entry name" value="Taxilin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127:SF13">
        <property type="entry name" value="GH01188P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127">
        <property type="entry name" value="TAXILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09728">
        <property type="entry name" value="Taxilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="386"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="249"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="386"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8304305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="445" mass="51652" checksum="DB2F0514F4C28517" modified="2020-04-22" version="1">MSTAANPTYAPGPANSRTTSMNANHTHADYPNGHHHHNDAGVKKGKQKKATDPSEASKLIAAKISQLELDAAGEKDQEAEIEREVKKANRELNNLTSKMDDLQKIETLQRRVTEHLADMKRLERDNQKNKKRGDVLQKEKDVARTDLGKSNSLREKLEKLCRELQKENNRLKGENKTLQDNEKKSREEWDQKFEEMLWQFQDYQDKKDHPQTVVVNPEIDELFKARFKSLIDQYELRELHFHSLLRTKELEVQYNIARFERERKAAEQEINRAKQLNQQVLTFSKTETELRNQLNIYVEKFKQEMEEMSKKTKRLEKENMALTRKHDVTTKNIFQMAEDQNKRTLEIDDLKKRNDKLRDIIDQMQRQGRGLAQGMAGTVEGEYVEGDLEATESEYEYEEGEDEGSEGEYDEDTEEDVHPEPPRPFGPVPPPPPAMNGMAAANGVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKT4</accession>
    <name>A0A5N6KKT4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_003810</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10265969at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000001">
        <property type="entry name" value="Paired amphipathic helix protein Sin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000002">
        <property type="entry name" value="Paired amphipathic helix protein SIN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000003">
        <property type="entry name" value="Paired amphipathic helix SIN3-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013194">
        <property type="entry name" value="HDAC_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08295">
        <property type="entry name" value="Sin3_corepress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00761">
        <property type="entry name" value="HDAC_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024807147" description="FAS1 domain-containing protein" evidence="9">
        <location>
            <begin position="24"/>
            <end position="1786"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="10">
        <location>
            <begin position="55"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="228"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="546"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="630"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="740"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1248"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="584"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="630"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="740"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="751"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="794"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1262"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1300"/>
            <end position="1309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8304406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1786" mass="198944" checksum="3000B90961939E79" modified="2020-04-22" version="1">MKMKYTFAIPFVLTALFASTISGKNIQRPLPDNNIGPAMPPKSEQSSDSIDGSDTIILSDVLGRDRSINIFAGFTRDVAQISQRFADSGQNTTILAPVNSAIMGLPRKPWEDPEDYDKLGANAYEGEDGEERAHKNLRRFVEAHIVPVSPWKEGEKVKTLVGDEVWWENKGGAKLLQPGNIEVSSMAGDVHNGQVWILKDHKALRVPTSNLIAYRSIDNQVLQPRSIVMNNQPHNGPPGFDRDRDMEEQHRQRTLQQQQEEMATQRERERDIERQERDRQHREQYQPAPPHQSNTGSIPLHQPVANRTTTAMHSPGGILATHGTPLGAPSGPGNAFGGPLHNDAARNLQHHAQNAAQQPQQQHMFNPEIFGPARGSGAPQSNVPLGVPGVPDVGFGRPQLLVPRETTQQDVAAAARLMPFGPATTGHTIPGPGLAQAGQQPILNDALSYLDQVKVQFADQPDVYNRFLDIMKDFKSQAIDTPGVINRVSELFAGHPNLIQGFNTFLPPGYRIECGADNNPNTIRVTTPMGTTVQSIPGAGRALGETVVSHGGGANGFYNPQRPGNWQQQPQPSIESPEAVFSPPHQSATVSYGHNQAPLGSYDAQAAAAAAAHQQQQRGVSQLTNAVSATLGQPPRNTQTPTPGGGSSNLNGSGAQAGMEKRGPVEFNHAISYVNKIKNRFQDKPEIYKQFLEILQTYQRESKPIQDVYSQVTTLFGTAPDLLEDFKQFLPESAAHAKAAAKAAEEATAMPDNSQDTQLGSRGPSGDPKLPIMGNFPIPTPATGKTEKKRKPLTQGTGSQMNNGGESSIRGAGQQQPNKRPKTHHNSKPLAADAAAVSPTLTPILPEPLPPASMSAASNEELAFFDRVKKYIGNKSTMNEFLKLCNLFSQDLIDRNVLVHKVSNFIGGSADLMNWFKAFVGYEGVDEVIDNRPKAPTGRVALSNCRGLGPSYRLLPKRERLKPCSGRDEMCQAVLNDDWASHPTWASEDSGFVAHRKNIFEEGLHRIEEERHDYDFNIECNSKVIQLLEPVAQQIVAMEPADRVNFRMPGAGPNGPSQAIYNRVMKKIYGTEKGPQVVADLFHDPCAVLPVVLARLKQKDEEWTFTRREWNPVWGAQGSVMYLKSLDHMGIHVKQADKKHFAAKHLVDSIKTKHEEQRRLRSSRGPTPKYQYSYQFADQEVIGQLLHIMIVYACNANQHSSSERRRISDFFEKFISTFFDLPYDFVARHTAGIDRGTPDDEYEDIAPAELSNGRGRRPPNGKKADLRRGVLDRGRNGTRGRGQKDDSATGSKESTPDVDSNGDEEVAEGNDDRAITEVTNERWAAVPGAVAVQGTKPLESDDLEMKADQPFQRDWYNLYCNQTVFVFFSIFQTLYQRLKDIKDAESSAKAEMERAKSGKPAKQIGLLSDRNDYFTSLEDGESCYSRVLDLVEDYIKGEVEDTKYQDYLRHYYLQTGWKIYTITDLLKSLCRLGSICSSPDNKEKTPDLIDQFIRNREAKETSYNIEINLRKQADKYIKDSELFLIRWYPKKNEATSQWVHRDETTFDLDIMQRKERWQYYTSSYVRIEPTEGVPRRLLRKSLLTRNLPSGDTDSEDGSNQRKPLVWDESLTLRICVNSYKIIYKEPGVEYFIYADKALGGGENGEARQRLKKVEESRNQRFHEKFGMNNRWMKEKSHEEVSRINQEFRKWVSEGVLPSTQATGVSTSVISGAASGAVPTATAAVDNEVDMAVLEGFSNDILFCFLLSFLFHWQLSKSLSSLNHLAVVDLFAKARMDIACCGEHLTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKU2</accession>
    <name>A0A5N6KKU2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_003818</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKU2"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0843">Virulence</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8304416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="32377" checksum="D335147450CBC7C4" modified="2020-04-22" version="1">MAIMGIVKRFPVLDNAIVKKLTEFLLPKDLKEKSRVHYQNSMKKATQRIERGDADRDDFFSHLLREKANGPKLTPEFVLAQSTTLIIAGSETTATSLSGMTYYLLKRPEALSHLQEEVRAAFTSNSEINSDSTASLSYLAAVIEEGLRLYPPVATGLPRESPGATADGFFVPKGAIVNVSGFSATHNEDYFTDAYEFHPERWLPPTHPLYNPRYANDNKDASKPFSLGPRACLGVNLAYMEMRVVLAKLVWAFDWKLVNTDLDWFRDAKNIALWNNPNLMVKFSAVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KL58</accession>
    <name>A0A5N6KL58_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_003825</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KL58"/>
    <dbReference type="OrthoDB" id="1738954at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14096">
        <property type="entry name" value="STKc_RCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000315">
        <property type="entry name" value="Calcium-dependent protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="95"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="456"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="563"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="481"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="173"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="223"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="8">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8304425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="583" mass="64883" checksum="47ACBFB36422D65F" modified="2020-04-22" version="1">MSSISQAIKNALHRGKGGAKANEDTNKKAQAAQHHIAKSDPNVVAHTANEMPQATAQNQMAGQPRRVDEDELARLLAEENESRNRLPKYPGLDRWELIEKMGDGAFSNVYKARDTEGRAGEVAIKVVRKFEMNSNQRANILKEVQIMRGLDHPNIIKLIEFSESRQYYYLVLELAPGGELFHQIVRLTYFSEDLSRHVITQVADALHYLHEVQGVVHRDIKPENILFERIDHIPTKHPKPRSAEDEDKVDEGEFIKGVGSGGIGRIKIADFGLSKVVWDTQTMTPCGTVGYTAPEIVKDERYSKSVDMWALGCVLYTLLCGFPPFYDESIAVLTEKVARGQYTFLSPWWDDISKPAQDLVSHLLTVDPKKRYTIEEFLNHPWIRGTDQPTYAALDAPPLATPAVERQRQLGGNLRAFNPDLLESPGAGRPMDFRSPGAVNLREVFDIGYSIHRQEEEAKRKKNFKQGYRGAAAMNPLNPINDEDLDESDEGDADENGVSSKVPKSGQSDVAQVGEALRNTQLNTKAAAPKGYGQHSPAVTAAARQQVRNRNGAFELSLDGATLLGRRHKKAAPSNLRESTVPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KL70</accession>
    <name>A0A5N6KL70_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LicD/FKTN/FKRP nucleotidyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_003820</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KL70"/>
    <dbReference type="OrthoDB" id="444255at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009100">
        <property type="term" value="P:glycoprotein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009644">
        <property type="entry name" value="FKTN/MNN4/W02B3.4-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007074">
        <property type="entry name" value="LicD/FKTN/FKRP_NTP_transf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15407">
        <property type="entry name" value="FUKUTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15407:SF32">
        <property type="entry name" value="PROTEIN (MNN4), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04991">
        <property type="entry name" value="LicD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025046920" description="LicD/FKTN/FKRP nucleotidyltransferase domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="LicD/FKTN/FKRP nucleotidyltransferase" evidence="7">
        <location>
            <begin position="93"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="LicD/FKTN/FKRP nucleotidyltransferase" evidence="7">
        <location>
            <begin position="188"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="276"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="347"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8304418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="365" mass="42436" checksum="AEC664C875179FCD" modified="2020-04-22" version="1">MRISWIITLPGLWSATSALAIQKRDADFYSVRTKSHKDMSGRRGDPSGKYFHESVFHPHYDGRFADKQLGYRERRQALSNLIQTYLATFSDIGVETWLMHGTLLGWWWNRKILPWDSDSDVQVSEDSMHFLASYYNMTVFHYKNSTYSRREQSDKLNVIDARWVDTTSGLFIDITTARYNYTHPAGEGMMSCKDGHEYRDTYIFPLRDTFFEGVPAKIPFAYKEILEAEYHEKSLTLTDFEGHHFDDDKMEWIPVKQEIQKPMEPQKEVQPPPKTEAQKAEETKQAAENANKVEEAKEKEKAKKLEEAQKATEEAKEKAKQKAAQEAQQNDTPPDEQKAADKRKKNENKMKEEAEKVENSVSPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KL73</accession>
    <name>A0A5N6KL73_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KL73"/>
    <dbReference type="OrthoDB" id="5569911at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="142" mass="16045" checksum="5A9B39F002D37C0B" modified="2020-04-22" version="1">MPSRGERDQLVSRKRKSMASQDLGYGEFDGQDDDYGNDRRAAKDRKENRESRDSDYGVKERRAAGRRYDVQAPDTSIVLEGYRADILNGFEEPQARYNPVSCIACIFLLCGWGSRKSLKTDVRRDGTGKCGASAKFDATQYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KL83</accession>
    <name>A0A5N6KL83_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003778</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KL83"/>
    <dbReference type="OrthoDB" id="287041at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8304371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="67" mass="7640" checksum="A6BEE709EE485DA9" modified="2020-04-22" version="1">MDRMGRADHWWTALNLTSANVAELDCGISVTRYARDYGTQNGIEYHDSNVMMHFSAAPKPDLYVYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMX3</accession>
    <name>A0A5N6KMX3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-chaperonin molecular chaperone ATPase</fullName>
            <ecNumber evidence="2">3.6.4.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_004352</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.10" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMX3"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000014">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000004">
        <property type="entry name" value="Heat shock protein SSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000005">
        <property type="entry name" value="Heat shock protein ssb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8305048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="600" mass="65358" checksum="99F7479A6D61B048" modified="2020-04-22" version="1">MADEVYEGAIGIDLGTTYSCVANYEGTNVEIIANEQGSFTTPSFVSFTDKERLIGESAKNNAAMNPKNTIFDIKRLIGRRFDDPHTTKDIQSWPFTVVDQDGSPFVQVEYLGEEKTFSPQEISSMVLTKMKEIAETKLGKKVSKAVITVPAYFNDNQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLGAGKSNKERNVLIYDLGGGTFDATAGDTHLGGQDFDTNLLEHFKKEFTRKTKKDLSNDPRALRRLRTACERAKRTLSNGASTTVEIDSLFDGEDFNAQITRARFEDLNSKAFNGTLEPVAQVLKDANLEKAKVDEIVLVGGSTRIPKIQKLLSEFFDGKKLEKSINPDEAVAYGAAVQAGILSGKATSADTADLLLLDVVPLSLGVAMEGNIFAPVVPRGNTVPTIKKRTFTTVADNQQTVQFPVFQGERVNCEDNTSLGEFTLAPIPPMKAGEAVLEVVFEVDVNGILKVTATEKTSGRSANITISNSVGKLSSSEIEKMVSDAAEFKSSDEAFSKKFESKQQLESYISRVEEIISDPLMSVKFKRGNKEKIESALSDAMAQLEIEDSSSDDLKKKELALKRAVTKAMSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMX8</accession>
    <name>A0A5N6KMX8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Endoplasmic oxidoreductin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">EYC80_004357</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">May function both as a monomer and a homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EROs family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMX8"/>
    <dbReference type="OrthoDB" id="269384at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007266">
        <property type="entry name" value="Ero1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037192">
        <property type="entry name" value="ERO1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613:SF0">
        <property type="entry name" value="ERO1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613">
        <property type="entry name" value="ERO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04137">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017205">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110019">
        <property type="entry name" value="ERO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 17" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 19" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024929324" description="Endoplasmic oxidoreductin-1" evidence="19">
        <location>
            <begin position="26"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="16">
        <location>
            <position position="423"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="18">
        <location>
            <begin position="101"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="18">
        <location>
            <begin position="423"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAB8305055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="22">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="565" mass="63697" checksum="69C8F957A4D63B4F" modified="2020-04-22" version="1">MKTAARAFYLGLFTLLSTCNSHVEAFESSKSKTVQSPDVCAISPKAIVSDACTTYATLDDLNREISPSLDDLTQTTDFFAYYRLNLFGKECPFWNDESGMCGNIACAVNTLDNEEDIPLVWRAEELGKLEGPKAGHPGKKLQQERPKKPLQGMLGEDVGESCVVEYDDECDERDYCVPDDEGAGSKGDYVSLVDNPERFTGYAGEGTKQVWDAIYRENCFSKSSFPHSASLGGSPFSLKEPATNELKSVLKQHGRQHILEEQREHSPNLPFVAETGLELEDECLEKRVFYRVISGMHTSISTHLCYEYLNQTTGQWGPNLQCYKERLHGFPDRVSNLYFNYALVLRAVTKLGPSLKDYTFCSGDPAQDQLTQFKVQTLMSKASKETRIFDESMMFVNGEGPSLKEDFRNRFRNVSRIMDCVGCDKCRLWGKVQTAGYGAALKVLFETDNNSKDVPILKRTELVALFNTLGRISHSLRAINGFRALIEAEENKHEEPVELTDRVNKPHNVIPEISRVDPIAEDFEDYDKQAKLKKETPTRFGYVLERITINVEYLQICYLGMGQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMY8</accession>
    <name>A0A5N6KMY8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">mitochondrial processing peptidase</fullName>
            <ecNumber evidence="5">3.4.24.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Beta-MPP</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">EYC80_003863</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. Preferentially, cleaves after an arginine at position P2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.</text>
            <dbReference type="EC" id="3.4.24.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.64" evidence="5"/>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMY8"/>
    <dbReference type="OrthoDB" id="10251424at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000002">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000001">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF149">
        <property type="entry name" value="GH01077P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="16">
        <location>
            <begin position="52"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="17">
        <location>
            <begin position="204"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAB8304469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="538" mass="59341" checksum="4FE7C7984A6F26A3" modified="2020-04-22" version="1">MASRRLALNLTQGLRTRAAPNVVSGLRRGFATPVTKNGVKTETTTLSNGLTIATEHSPWAQTSTVGVWIDAGSRAETDKTNGTAHFLEHLAFKGTSNRTQHQLELEIENMGGHLNAYTSRENTVYYAKAFNSDVPATVNILSDILQNSKLEPSAINRERDVILRESEEVDKQLEEVVFDHLHATAFQGQPLGRTILGPAQNIQSIQREDLTNYIKTNYTADRMVLVGAGGVPHQQLVELAEKHFAGLASQPHTSAALAVANAQKQKPEFIGSEVRVRDDTIPTANIAIAVEGVSWKDDDYFTALVTQAIVGNWDKAMGNAPHMGSKLSGFVHKNDLANSFMSFSTSYSDTGLWGIYLVTDKTTRIDDLVHFTLREWSRLSYNVTEAEVERAKAQLKASILLSLDGTTAVAEDIGRQIITTGRRMGPEEIERVIGAISEKDVMSFAQRKLWDQDIAISAVGSIEGLLDYQRVWGTSVYDAGLVCTHRSSIKFVHFVQSGPPGVNMPKNYTHESHNYENTGGFRIKWPSYPLRNAHIPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMZ5</accession>
    <name>A0A5N6KMZ5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CDC20/Fizzy WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_004304</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMZ5"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF8">
        <property type="entry name" value="FI02843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="9">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8304997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="295" mass="33008" checksum="9CB12DEC2D6910FB" modified="2020-04-22" version="1">MHGHDTRVGVMGWNKHTLSTGARSGLVFNHDVRIAQHKVAELVSHTSEVCGLEWRADGAQLATGGNDNLVSIWDARSLAVPKFTKTNHKAAVKALSWCPWQPNVLATGGGSYDRHIHFWNTTTGARVNSIDTGSQVTSLRWSPHYREIVSTSGFPDNSISIWSYPTLVRNVEIPAHETRVLHSCLSPDGQMLATAVLEGLREEDRPKCIRICRCFRKGRHGQADDYQIDRSRIALGATAWCLVDFDLHKSPWQKVLHLVQVDALTMNEWIPMVVVIYLWLAYSFSGGTFCISYIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMZ8</accession>
    <name>A0A5N6KMZ8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA(His) guanylyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMZ8"/>
    <dbReference type="OrthoDB" id="62560at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038469">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="66" mass="7731" checksum="DBC38D0399C0CEEE" modified="2020-04-22" version="1">MPEAIDEDSAKTANEKELSKTQAEKDRKRRAKARITVQHIDVIKDEFWEKRPWLLSNKPGKIPKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KN96</accession>
    <name>A0A5N6KN96_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein BIG1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_004445</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BIG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KN96"/>
    <dbReference type="OrthoDB" id="9985059at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006078">
        <property type="term" value="P:(1-&gt;6)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037654">
        <property type="entry name" value="Big1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046756">
        <property type="entry name" value="VAS1/VOA1_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28285">
        <property type="entry name" value="PROTEIN BIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28285:SF1">
        <property type="entry name" value="PROTEIN BIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20520">
        <property type="entry name" value="Ac45-VOA1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024872641" description="Protein BIG1" evidence="11">
        <location>
            <begin position="19"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="V-type proton ATPase subunit S1/VOA1 transmembrane" evidence="12">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8305152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="314" mass="34806" checksum="91D42282E0544D78" modified="2020-04-22" version="1">MRYSIAGSLLCCAAVVQAFKDTSPFLLFSSSELPSSMQIESQELDTASSVLQNTKSFLSTCPSDVYIIIQQAALAASDFTAYNSVPYMKAAITDSRVRATYTVTDVVYEGRNLAEELAEHIEKSCGKKVERRNNAGLESANGNGNGVTLSNFNALSTGKVARAEELNDQDIMLNSVFYEHLSSGPEYTVIYTTTPIGFVLEQDVPESAIYQAEFDATAHIDLKRDFRVRADNSTNAPDTRPLFEKYQYFTPGIFMGLVVGILLLSILYVGRWDHLRKRSSSNLIGDTMEERVDWNGLVWNGVNMKQSKCMILCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KN97</accession>
    <name>A0A5N6KN97_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AGC-kinase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KN97"/>
    <dbReference type="OrthoDB" id="5408302at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="651"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="825"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="880"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="895"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="930"/>
            <end position="939"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="977" mass="106321" checksum="97E318D2699264CE" modified="2020-04-22" version="1">MGTKKFFGPMTPDSDIKPASRRPTGAQMPSPPPEAPPPQSSKGRLKMLNPMALLARRRTSQAITQLTPESLITNFSSNDNFDPRIKGTVVHDFSAPRGPRRNMSHKDVNSADGARPFQRSPYTDSATSEKVGNHTPVFTENFEEEQYPAAGPHVRKTNDLSDLTPPKLPYARESPKTVDHGSTSKDKDELQAGDLKRLSAQKSPSNTMPTVPEKAESSIPAEAKHISIDPALTPPKSYPSSKKGARARNVSDVSAKDIPKHMKSTSSRFSFDMIGAAEQERLLEDRHRQKALEKKNDPDHGDQQIYDEDDDFNYDDMMDDDGLEERIPGVNADYDEEDIFEGFDGGYEEDTPGINTTSLEEIEETEEQQEIEPAAPAEDKPQPDMLNGNVAGFTFQPHVSSPMSAYTPGTTTTPRDSNGQIIGFAMTKYSPHLTPDLSHSVFTPTSPESDSALAESKTSEVQGIPDSNLQCLGIAPGTPDELRLEVVPQQESKSTSFHQIPGLDDDDDLYFDDGLIGLEGDEDFIGDAGNFDESIFDNNDTDQYGRPIKDQFMTTKIANAFEASAMGLSEELKEDTLSPLSPVGNRPTGGLAPQPSFTDNRGSATTEAQPVMQGLTQDTLAAYQASLAAAAFSAAASGKFRRDSTQSLFHLDSDREENQPGLVTDSGHTSSHYEQLSPSYDDDFDYDDALEDDEFIAAANAEALANDQDGFYGQEFGFYSQPAASSAEFVNGGYFGPRGMDGMIRSQSGRIAFREPNLTPITERSEYSNRNSFMSVSHLHAPPGSSPMVSPGLAQLMIAQDYERTPDMSLEALLKLRGRAWGGSQASVKSLGSNGNGNGSPKSVDGGGSPVAGGPLVQPPWGGHRRKGSAFSLVNEEVESEIDTRKLNANQASPELEHKNIETKDLSAGNEYEGEDEKPKRPSYAKQHKSTTSAESISYSKEDDPIKGERWVLERRRTADSGEVEVLGREVQNGGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KN99</accession>
    <name>A0A5N6KN99_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004398</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KN99"/>
    <dbReference type="OrthoDB" id="3366823at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8305101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="68" mass="7584" checksum="8D746A77E270CBB5" modified="2020-04-22" version="1">MLAACAIMAMEFDVRILADEEALGMDPKFYGLGGQRPVGKVPFKIRRRVTGFSGRNSQIRIRLTLWAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JLU7</accession>
    <name>A0A5N6JLU7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">xanthine dehydrogenase</fullName>
            <ecNumber evidence="4">1.17.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">EYC80_010214</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>hypoxanthine + NAD(+) + H2O = xanthine + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24670"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>xanthine + NAD(+) + H2O = urate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="20">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="20">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="20">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="20">Binds 2 [2Fe-2S] clusters.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the xanthine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.4" evidence="4"/>
    <dbReference type="EMBL" id="VIGI01000025">
        <property type="protein sequence ID" value="KAB8288210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8300278at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004854">
        <property type="term" value="F:xanthine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000015">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000003">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.50:FF:000001">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000002">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000004">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000004">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.120">
        <property type="entry name" value="[2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.50">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.365.10">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.50">
        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046867">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022407">
        <property type="entry name" value="OxRdtase_Mopterin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014307">
        <property type="entry name" value="Xanthine_DH_ssu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02963">
        <property type="entry name" value="xanthine_xdhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444:SF3">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="MoCoBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20256">
        <property type="entry name" value="MoCoBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000127">
        <property type="entry name" value="Xanthine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="CO dehydrogenase flavoprotein C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="CO dehydrogenase ISP C-domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="CO dehydrogenase molybdoprotein N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="Molybdenum cofactor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00559">
        <property type="entry name" value="MOLYBDOPTERIN_EUK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 20" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="9 19" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 20" id="KW-0408">Iron</keyword>
    <keyword evidence="12 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 20" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="13" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="22">
        <location>
            <begin position="33"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="23">
        <location>
            <begin position="262"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="18">
        <location>
            <position position="1294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="793"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="824"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="828"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="906"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="938"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="940"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="1036"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="1105"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAB8288210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1379" mass="150990" checksum="C7B08B4E0F09B3C3" modified="2020-04-22" version="1">MAPIAVSPDRSPEPAVPLASSQSLSSVTTTYDDTLRFYLNGTRVIIDNMDPEVTLLDYLRGIGLTGTKLGCAEGGCGACTVVVSQYNPTTKKIYHASVNACLAPLVSVDGKHVITVEGIGNTKRPHPTQERIAKGNGSQCGFCTPGIVMSLYALLRNDSNPSEHDVEEAFDGNLCRCTGYRPILDAAQTFSSGAGCGKSKANGGGGCCMEKSEGGGGCCKNELKDDQPIKRFTPPGFIEYNPNTELIFPPPLRRHEFKPLAFGNKRKKWYRPVTIEQLLEIKNVYPSAKIIGGSTETQIEIKFKAMQYTTSVFVGDIPELRQFSFEDDHLEIGGNVILTDLESIVQQAEKHYGPENGQVFKAIHKQLKYFAGRQIRNVGTPAGNLATASPISDLNPVFVASNATLIARSLEKVTEIPMSEFFKGYRLTALAPDAIIASIRIPVTQKGEYLRAYKQSKRKDDDIAIVNAALRVAIDDSQVVTSTSLVYGGMAPTTIAARKAGAYLLGKKFTDPSTLEGTMNALEEDFNLSFSVPGGMATYRKSLAFGFFYRFYHEILSKLEVKDLEVDAQVIPEIERIISFGKEDREATVAYQQNVLGKASPHVAALKQTCGEAQYTDDIPVQKNELYGCLVLSTKAHAKITSVNYAPALDLPGVVQYVDHTDMPSPEANCWGAPVCDETFFAVDEVFTTGQPIGIVLADSVARATAGARAVKVEYEDLPAIFTMEEAIEKESFFDHYRYIKKGEPEKAFEQADHVFSGVSRIGGQEHFYLETQACVAIPKIEDGEMEIWSGTQNPTETQTYVAQVCDVAANKVVSKVKRLGGGFGGKETRSIQLCGIVSLAAKKTGRPVRCMLNRDEDMITSGQRHPFLSRWKVAINKDGKIQALDLDMFCNGGWTQDLSGAVLDRSLSHSDNCYMIPNIHVRGRVCKTNTMSNTAFRGFGGPQGLFMAESYIEEVADRLGMPAEKLREINFYKPNEQTHFNQALKDWHVPLMYKQVQEESNYAARRDAITKFNAEHKWKKRGLSIIPTKFGISFTALFLNQAGALVHVYHDGSVLVAHGGTEMGQGLHTKMMMVAAEALGVPLSNVFISETATNTVANTSSTAASASSDLNGYAIFNACAQINERLAPYREKFGPGATMKELAHAAYFDRVNLSANGFYKTPDIGYTWGPNTGQMFFYFTQGVTASEVEIDTLTGDWTCLRSDIKMDVGRSINPSIDYGQIEGAFVQGMGLFTTEESLWFRAGPMAGQLATRGPGAYKIPGFRDIPQEFNVSLLKGVEWEELKTIQRSRGVGEPPLFMGSAVFFAIRDALKAARKEYGVTAEIGEDIKGGGLLRLESPATPERIRISCADPILKRAEVKPKEGEKSFFISPQIETGTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JLW1</accession>
    <name>A0A5N6JLW1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exocyst complex component Sec6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_010213</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000025">
        <property type="protein sequence ID" value="KAB8288209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JLW1"/>
    <dbReference type="OrthoDB" id="190098at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051601">
        <property type="term" value="P:exocyst localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010326">
        <property type="entry name" value="EXOC3/Sec6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21292:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21292">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06046">
        <property type="entry name" value="Sec6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8288209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="39197" checksum="78FD0EFEB0D5275A" modified="2020-04-22" version="1">MTMDVASIKLSDLLHHPDDLDKIPALKLEYTRKKSAVDSQLRSGLKEQLEVTQAGMHGITDGQRTVQLIKEEMMKIDKLCAEAQNMIKDFPNINLVSQTHRNFTAVETMRRNLVDFNERLTKVEGLLEEDDRDEDNMANLLAIHYELTQLRNIRDDAMEQILRADDAGLQGTLEDYFARLDDTIDWFDEHIGKVAMNLIEVVVQGNSSLVVRLAVVIEAEEKSDKRVMALQEALKDHKEMAARFKSITDGAKSTRGYKEKFLMAIKLKAEGDIEGTKQAFLEDPSKLEKSLRWFFNDLNAVKQGMVPLMPKKWKILKTYGKIYHQLMHDFLIGMIDDPDTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JM90</accession>
    <name>A0A5N6JM90_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_010111</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000033">
        <property type="protein sequence ID" value="KAB8287275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JM90"/>
    <dbReference type="OrthoDB" id="2341546at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF21">
        <property type="entry name" value="REGULATORY PROTEIN LEU3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="46"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8287275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="515" mass="57701" checksum="018AE4B387411E37" modified="2020-04-22" version="1">MASTIVINDGDHPHSGSDDTTSHKSIGKRSRDEMEKPSKIPASIKSCNECRQQKLGCNVVKEPFKACCRCTRLGIHCKLDSDFKRVAKRHKHSEMQKEIEELRELVAKQSAQLAAANSPDQSGKGKNPSSSTDSKPKDQKIDDILVSGISLGIIIYAQFLILDPTLVLNLSKAYMKFLWNSISDMPQRSASIKALALLCTWPVPLIRGFTKSRNDKASATMGLSELDPTWMLSGIMMQIALQTGMHRPRHAQDFLKQTRDVSEAELRDRKLIWAMCNIVSQSVSTANGQPTITIYDWGLGDGLEQNSEILPQGIKDRLKIEKFCQKVSKNLYGNSSEITGVLSDIDEQLSATNALERQYQQLESESLKFSSLNKLYLLAARLHLHTFAFYVPEFSRNHFSALSSAYSSATRFIQALLDYDLHSEAILPYCSYYILKNLICASCVLLKILNSTYAMQFDSTQGRSLFNAAILALRSTSLATNDFSDRIAEALARMWRSAGSGDLNRRRGNFFSYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JNY6</accession>
    <name>A0A5N6JNY6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_011096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000018">
        <property type="protein sequence ID" value="KAB8290227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JNY6"/>
    <dbReference type="OrthoDB" id="5370059at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="152"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8290227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="35064" checksum="048B29D836379BD9" modified="2020-04-22" version="1">MELWACGFNAWNQLQFEDDLSDEPKDLFTFKRVLTSKGSIRIVGTSFSACLAAVSDDPLGSPEKIKVAGSPDGFLQAQLEQINESRPSQNISTNATVAGNDKIASFTPKTLTQYPSLPTYLSKTTPDFALPLPNITQLVSNTTTFTALTHSGTVYTWGDERYPSRLGRETSSSTPAHNPSPLSSLTSLPTGPIHKLSSSGPLTAALTTGHDLYIWGTTTIPSIIPELSQFPPSDNYDPIPLDIHGADILDFGIGENHMLVLTTEGEVYVIGENGNGQLGLGEDEKGRCEEWRRVDLEFGEGAKKKCVGVWAGYKCSFVAVVDSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSC9</accession>
    <name>A0A5N6JSC9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Formate dehydrogenase</fullName>
            <shortName evidence="6">FDH</shortName>
            <ecNumber evidence="2 6">1.17.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">NAD-dependent formate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_006583</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>formate + NAD(+) = CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:15985"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.9" evidence="2 6"/>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSC9"/>
    <dbReference type="OrthoDB" id="418179at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042183">
        <property type="term" value="P:formate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05302">
        <property type="entry name" value="FDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000057">
        <property type="entry name" value="Formate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03210">
        <property type="entry name" value="Formate_dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033689">
        <property type="entry name" value="FDH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005750">
        <property type="entry name" value="PRK07574.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42938">
        <property type="entry name" value="FORMATE DEHYDROGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42938:SF9">
        <property type="entry name" value="FORMATE DEHYDROGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="8">
        <location>
            <begin position="33"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="9">
        <location>
            <begin position="130"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="175"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="231"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="312"/>
            <end position="315"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="6">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="6">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00071864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8291788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="374" mass="40991" checksum="B65841846EF377A3" modified="2020-04-22" version="1">MVKVLLVLYDGKKHAEEVPELLGTTENELGIRKWLEDQGHELVTTSDKEGENSEFDKHLVDAEIIITTPFHPGYLTAERLAKAKNLKIAITAGIGSDHVDLNAANKTNGGITVAEVTGSNVVSVAEHVVMTILVLVRNFVPAHEQIQAGEWDVAAAAKNEFDLEGKVVGTVAVGRIGERVLRRLKPFDCKELLYFDYQPLKPEIEKEIGCRRVTDLEEMLAQCDVVTINCPLHEKTRGLFNKELISKMKKGSWLVNTARGAIVVKEDVAEALASGHLRGYGGDVWFPQPAPKDHVLRYAKNPFGGGNAMVPHMSGTSLDAQKRYADGTKAILESYLSGKHDYRPEDLIVYNGDYATKSYGERAKNSGSAGANKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSE1</accession>
    <name>A0A5N6JSE1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0357 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSE1"/>
    <dbReference type="OrthoDB" id="447314at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018559">
        <property type="entry name" value="DUF2015"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28023">
        <property type="entry name" value="UPF0357 PROTEIN YCL012C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28023:SF1">
        <property type="entry name" value="UPF0357 PROTEIN YCL012C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09435">
        <property type="entry name" value="DUF2015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8291802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="176" mass="20314" checksum="79CD275CD21428F6" modified="2020-04-22" version="1">MYTPYHELPHSFENDIESGLSSSNFNLSQNLLDSDPRNGLSDNGKREIQKIMKKKKVNFDEARRIWMQETFKKENIGPDGRPRDPKFVSFSIIISMALSSIKKNSSDLRQGIDILIIESEERETKWGEQNRIGIWISEIYPGWRGRTRLAGLLVLKVITSKWAGRFEVFSPAAQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSE4</accession>
    <name>A0A5N6JSE4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 19</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 19</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED19</name>
        <name evidence="11" type="ORF">EYC80_006586</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSE4"/>
    <dbReference type="OrthoDB" id="2160599at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013942">
        <property type="entry name" value="Mediator_Med19_fun"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08633">
        <property type="entry name" value="Rox3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8291793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="100" mass="10714" checksum="959824096C1BBCD8" modified="2020-04-22" version="1">MGVPKQNRSAADIPRPRRTSVKKRSYGDASYEGYGEGYIDDDAEYSAGDGDDRSGGRKRPKKVGSVLYPSNVQANKGKTPSSHGFQGPMRQSYGPGMVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSE8</accession>
    <name>A0A5N6JSE8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Malate dehydrogenase</fullName>
            <ecNumber evidence="3 12">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">EYC80_006597</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 12"/>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSE8"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000001">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF16">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="13">
        <location>
            <begin position="4"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="149"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="9"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="119"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAB8291809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="332" mass="34427" checksum="96C9E4CCBA1A81E1" modified="2020-04-22" version="1">MGFKAVVAGASGGIGQPLSLLLKTSPLITELALYDVVNTPGVAADLSHISSPAKITGYLPKDDGAKLAFKNADIIVIPAGIPRKPGMTRDDLFNINAGIVKGLIEIIADVAPKAYILIISNPVNSTVPIAAEVLKAKGVFDAQRLFGVTTLDVVRAETFVAEIVGKANPQELTIPVIGGHSGETIVPLFSQAKPDVTIPADKLDALINRVQFGGDEVVKAKDGAGSATLSMAYAGFRFAEKVLKALNGEKGIVEPTFIYLPGVPGGEAIAKETGLDFFSVPVELGTNGADKAQNPLSNINDAEKKLLAAAVEGLKGNISKGVTFANAPPQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSE9</accession>
    <name>A0A5N6JSE9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">malate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_006597</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3"/>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSE9"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000001">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF16">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="8">
        <location>
            <begin position="74"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="9">
        <location>
            <begin position="218"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8291812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="401" mass="42026" checksum="D0F11C268528A884" modified="2020-04-22" version="1">MDAKVSIPIQLEGARLGFIILTQELTTKASYTESSQIPIYTHLHTSTHISKWVSKLVGLLNVKGGDWILTMGVIVVAGASGGIGQPLSLLLKTSPLITELALYDVVNTPGVAADLSHISSPAKITGYLPKDDGAKLAFKNADIIVIPAGIPRKPGMTRDDLFNINAGIVKGLIEIIADVAPKAYILIISNPVNSTVPIAAEVLKAKGVFDAQRLFGVTTLDVVRAETFVAEIVGKANPQELTIPVIGGHSGETIVPLFSQAKPDVTIPADKLDALINRVQFGGDEVVKAKDGAGSATLSMAYAGFRFAEKVLKALNGEKGIVEPTFIYLPGVPGGEAIAKETGLDFFSVPVELGTNGADKAQNPLSNINDAEKKLLAAAVEGLKGNISKGVTFANAPPQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUG1</accession>
    <name>A0A5N6JUG1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">V-type proton ATPase subunit e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_008184</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase e1/e2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUG1"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008389">
        <property type="entry name" value="ATPase_V0-cplx_e1/e2_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05493">
        <property type="entry name" value="ATP_synt_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8292465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="8759" checksum="F0D46044447FE24B" modified="2020-04-22" version="1">MANGWSIVIGLIIVVLASIAAWFLSPKGETQTIWRSSLILSFASCYIMWAITFLAQWHPLIVPRRGDLRPEYARHMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUG3</accession>
    <name>A0A5N6JUG3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006654</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC123 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUG3"/>
    <dbReference type="OrthoDB" id="360540at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009772">
        <property type="entry name" value="CDC123"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323:SF6">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 123 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323">
        <property type="entry name" value="D123 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07065">
        <property type="entry name" value="D123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8291876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="266" mass="30566" checksum="2124C4B88CD794CA" modified="2020-04-22" version="1">MECNTPNDIYLLLKSSDFITHDLEHAFDGCDEDPTLTKENTKFVLVLRKWFKVNPSCEFRCFVRDRRLIGICQRDLNYFDFLFPLIPTLREAIQLYFDKILKDTFPDRNFSFDVYIPEPFDKVRLVDINPWAPRTDPLLFSWLELLTLSVPPPLLGTADSPSVPPLPTHSSDEDDGPDAIEEIEWMPDFRLVKKDDPEAYSFASPQYSAHKMPQEVVEAGASGEGGMREFADNWQRMLNGELEMMRAGEDSDDDDDDNDPGGRVDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JUI3</accession>
    <name>A0A5N6JUI3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_010088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JUI3"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8291414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="140" mass="16020" checksum="2F5D2A1E8FF73E51" modified="2020-04-22" version="1">MSLVGNACTSANEGAEAGLQLEHNGIWYEFIYIPSRRVVCPLETLSLISVFPVTILFSKVKVQKTFPYAQIRIHRYHSDTYLKKVPARPQMIALIIPLPTSAQKDYKTPEKRQVIFIPTPNAVKRVVIFKGPLRHLHLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWJ3</accession>
    <name>A0A5N6JWJ3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phospholipid:diacylglycerol acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWJ3"/>
    <dbReference type="OrthoDB" id="190846at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003386">
        <property type="entry name" value="LACT/PDAT_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02450">
        <property type="entry name" value="LCAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="561"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="664" mass="74849" checksum="6E1069F4B789887A" modified="2020-04-22" version="1">MLEGITMDSLMDVLPAGFVKDARDLAKGEREALNYDSFSVGLRLKAQGIHAKHPVIMIPGVISTGLESWGTTNASLPYFRKRLWGSWSMMRALVADKEGWKRHIMLDKRTGLDPPGIKLRAAQGFDAADFFITGYWIWSKILENLATIGYDPTNSFTAAYDWRLSYANLEVRDQYFTRLKTHIEMAKNISNKKVVLVSHSMGGQVLFYFMHWVASPSGGNGGDDWVDKYVDSWINISGCMLGALKGLPAVLSGEMKDTAQLNAFAVYGLEKFLNKEERAEIFRAMPGISSMLPIGGDAVWGNATWAPDDAPGQEVSYGQFLNFKNQNTSTGYRNLTVSQSLNYLFNTTEDWYHKAVEGSYSHGVAHTTAEVEANEKDPRKWINPLETRLPLAPNLKIYCFYGIGKPTERSYFYRHSDNPLSSLNITIDTGLTQANIDHGVILGEGDGTVNLLSVGYMCNRGWKYHRYNPAGVKVKTYEMPHEPDRFSPRGGPNTGDHVDILGRQSLNDLVLRVAAGRGEEIEEMVVSRIGEYAGNVKIEEEEQYKVKEDDGNGEERRGRVRDKIEEKAQEVLEVLENIVENKNKNKDELTGSFGFGMRKGLEFYVRLCAIQHDVTRRHKGKSGRRAWLGWNKAFWQDKGKMNYTSCEGMGFDMVLLFMIQYVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWK1</accession>
    <name>A0A5N6JWK1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Hydroxymethylbilane hydrolyase [cyclizing]</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007643</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWK1"/>
    <dbReference type="OrthoDB" id="5595751at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12390">
        <property type="entry name" value="UROPORPHYRINOGEN III SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12390:SF0">
        <property type="entry name" value="UROPORPHYRINOGEN-III SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="HemD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8293318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="11248" checksum="4B7C472D1EA9D653" modified="2020-04-22" version="1">MIENLQRMGRIPVFLLKTKSVPNDGYEERLEEVRYNVVKFMDEGVKEVKKFLRDRDIGKEDGKKYGGLIFTSQRAVELFAKLVEEGRQDGNVMNGHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWK2</accession>
    <name>A0A5N6JWK2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007646</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWK2"/>
    <dbReference type="OrthoDB" id="1930760at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8293321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="179" mass="19479" checksum="D902348A4BE41935" modified="2020-04-22" version="1">MDWSTGPVGPIELAQEKPINVMADLDVGGGAYRLEFLQDYIGIPSADKDISFQVLASCMEVGAKILEVQRKDSIWNVQVIASINIEIPRFPNPTNKSQLCYASAVQPAIKDGGMVFVSSYFNKRRLSGTPGKVQPATTDGDKIFVSTCFNKRQLGVYKLIEGDNSGIEEITMGVESLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWK9</accession>
    <name>A0A5N6JWK9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_007664</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWK9"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000637">
        <property type="entry name" value="HMGI/Y_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF38">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00354">
        <property type="entry name" value="HMGI_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="272"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="166"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="224"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8293342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="802" mass="91211" checksum="236677345530184D" modified="2020-04-22" version="1">MYQSNKPFPQLSCSVIPVKIERNGISRFTFNRSVPLNRIFTLTPKLDHFHTSANTQWTVDMDMQLTPVSSEEAIFEWSDHSTSPDRDDVEEIIRQTQGGYRFTPRQPRVVRAPTRRRVQIDESCDHSSVNFQNYKFERFDMRAGSMDGSDGSNSSAITVITSATSSCGGDPWSAGGFVEEEEEGHEHNGSAGGSWDGEHTHEHSQDQDVDMLLEPKLEPLEEELNLESVAPRTPTTLLSPTQAKRPRGRPRKHPIQTTEPLNKVTKGRSKTGCITCRRRKKKCDEAKPRCQNCEKNAVVCEGYPEKQVWKSGKEKAEEGTTLWRYQLRPEKLIVTTARMRRVSIPSITLQPVIHGVETSGDKVFFEHYIYRLSHIFTVEGAENNAFKDQLLPMAVRHVGLMHSILALSSKHIDYDSDYGQRLLQQHPDVDRETLEERSQYHHAEAMKELHHDLDRQEKGDIDNTVVSARFGQMLCLVLQTLADPNPNGAHRIHLTAYQHLIQQSPPEEGPFLNFIQEFFQFHIILDEIISLPEGRARLGTVSDDWDIPSNIIQPDAVRLLGVNDGLFLFMSKITNIRNSIRNNMQKKIDPLVDYKALYRAAEIDAGIRDWKPAWPAGDSRDLAGLLYKQMMWVYLWRTIYPPKNTCWKPDPRITKAVDDGIALLAQVPPRDPAQTLVLAPAFIIGCAAFEKRQREPIRKAIGVVKAYMEYRNSDAALRVLEEVWNPQHGYGFLGYLKIDLLVVLISQYDQTYSSSPNRIKSVRHNVTTAISPIPVLQQSRIDMWCNGGIPIDMGLTSHLVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWQ9</accession>
    <name>A0A5N6JWQ9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWQ9"/>
    <dbReference type="OrthoDB" id="2193432at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="327" mass="36175" checksum="3A3E421F50D61DA8" modified="2020-04-22" version="1">MNNGSQSQAPQGQPGGSQPSSGIARMQLFKPEMMRSLPSGGFSDEDKIKWENGLRGLWTQIENNSAESPSHQEAKRKLIEFSKSLTLKMQNYRVQQQRQQVQQAQQNQQAQQNQPGQQPQQAPQTTAAPSNNSAQQNSAPQQHEQTTQSQVAQASGSNAGSSSQQQPRAPPTTAIPERLLNHVQTFPWTAPPELTPKSEQWNQWVAGVKSKYAKGLMSMDKLTAQLKSLEDYIKKKREDRTATEQDEADFQKRNTEWRAQHAAARKVVEDIRDNQKRLQQQQNPQHQGQPQHPQQSQAPGSGSSDSNLTGNPSGISSQGNQGAQASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWR9</accession>
    <name>A0A5N6JWR9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWR9"/>
    <dbReference type="OrthoDB" id="190846at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="111" mass="12640" checksum="438C2782F481C66C" modified="2020-04-22" version="1">MPHEPDRFSPRGGPNTGDHVDILGRQSLNDLVLRVAAGRGEEIEEMVVSRIGEYAGNVKIEEEEQYKVKEDDGNGEERRGRVRDKIEEKAQEVLEVLENIVENKNKNKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYJ7</accession>
    <name>A0A5N6JYJ7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_009675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYJ7"/>
    <dbReference type="OrthoDB" id="161814at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF73">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN CTR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0187">Copper transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8294243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="237" mass="27208" checksum="AED53F28BBA7B158" modified="2020-04-22" version="1">MDTNMDTVMASSNLSSSTAAPSMSNSSCKMFMLLNWHTLDTCYLTSTLHIRTPLHFTLICLFSFLLPIILEITRRYQRIYDRYLRAKQIHYLQNAHESSPLDEISEKLLGGPNFKRTNWDSSVVLEQGLRAGLHLVQFALSYCVMMMWMYGNGYLLICILLGAMTGFGMFTRDMLAVFVQESDTDEREQTIIVARFERALRDCRIAFPSAQVRWLPSERTNQKSSINPMIQSHIPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYP9</accession>
    <name>A0A5N6JYP9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYP9"/>
    <dbReference type="OrthoDB" id="2443965at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8294289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="100" mass="11597" checksum="995374AF65AFA957" modified="2020-04-22" version="1">MKHVIHFNISYLFHQILSRICQIYSQSSRYVHSSKIIIRTPELKHTTIAIAIATMEIDASNIPLPTSEDLSPTEQDLLDEYERLAENMKTVLRAYSRNHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYQ1</accession>
    <name>A0A5N6JYQ1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Threonine aspartase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_009716</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYQ1"/>
    <dbReference type="OrthoDB" id="77601at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04514">
        <property type="entry name" value="Taspase1_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.30:FF:000007">
        <property type="entry name" value="Similar to threonine aspartase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037464">
        <property type="entry name" value="Taspase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF8">
        <property type="entry name" value="THREONINE ASPARTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="202"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="2">
        <location>
            <begin position="403"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8294292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="586" mass="62286" checksum="14A8F8E03E1B1293" modified="2020-04-22" version="1">MSELTQRSTSQRQQSQIATMDGSADTRRPRVVQSQPYVSAIFVHAGAGYHSTTNEHIHLGACNDAARAAMRVLKAGGSAVDAVEAAIKVLEDKEITNAGYGSNLSIEGIVECDATVVDHLGRSGACGATAQIKNPVSLARLVLEASSRPLSLRRVPPNLLVGQGATDFAWEHGIPVVPHDMMCSKNARERYIRWREDLRRAEGGRMTPSSTNSSQVADDEVAAREYEERVRAQQRRDHTNALMTGTWNEGQPDSPSTSSPGRACAQECGNYSQRPGTPPSRGYFQMNTPGRGASRSPVGTTPAKRARLAALSDGSPGRVHSLLSPSVAAGGMFSEPNISLSTGSSAIERPSSTDGYASPVDQEKVIEMHSALLNLAQEGTIEGPNESTIESTPKKLDVDLITDTVGAIAIDMYGRIAAASSSGGIGMKHRGRVGPAALVGIGTAVIPCDERDEDQVSVAAVTSGTGEHMATTMASQKCADRLYHNTRRARGGQDMEANEDEAMESFVQADFMGHPGVCGSNSAGAIGVMAVKKTQYGYFLHFAHNTDSFALASYASNEKDAKCVMSRLGDHGNVVRGGRKIRTEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYR4</accession>
    <name>A0A5N6JYR4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYR4"/>
    <dbReference type="OrthoDB" id="3564184at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8294195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="121" mass="11968" checksum="F073CA02CFBDBB56" modified="2020-04-22" version="1">MAPKAFEAIKAKFKALLKGKKSKKAEADPAADATKTDAAPAPATATSEAAPATEATAPEGDAAEPSTATETPAAPTTADHAPAVVEPANTTEPAAPEASKDEEPVKTEPSAPIVAATAPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZ11</accession>
    <name>A0A5N6JZ11_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_009680</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZ11"/>
    <dbReference type="OrthoDB" id="346839at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051229">
        <property type="entry name" value="ALYREF_mRNA_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025715">
        <property type="entry name" value="FoP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965">
        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF35">
        <property type="entry name" value="RNA ANNEALING PROTEIN YRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01218">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="75"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="171"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="233"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="172"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8294250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="326" mass="34544" checksum="313ACDADBFB74404" modified="2020-04-22" version="1">MSSDKLGQSLDEILATQRATGTGRGGRGNGRRGGRASGGRNATAAPVGGVSKSKKPVKGSTKATPTGPSGGNVPSRIVVSNLPYDVTEQQIKEYFHEAKLHTKTVQLVYGPNGVSRGEANITFHRPGDAAAAVSRLNGVKVDNRALRVQLLVDAQAAAVFEEKVAKKLMDRISTTPKSQPKSAVPNKSNGKDQGAKRGGKRGSRGGSNTARPTKKTAEELDLEMADYWESGNAAGADAGGDNNQAASGAAQPATNGDANMDDEILEARSEIKNTCAHPIPPALHLCRLYYCYFLMLLFLRFLSWGFFSTVGWLGYGSGEMTTSYRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0A6</accession>
    <name>A0A5N6K0A6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_007143</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0A6"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000007">
        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="11">
        <location>
            <begin position="692"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="592"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="747"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="626"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="771"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="785"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="797"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="834"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="855"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8295226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="988" mass="105008" checksum="BB63E68E587B553A" modified="2020-04-22" version="1">MPGTAQYLERGGFLQTFRDSSEDWHTSEESQSNNTTSSGSIGTQHDFRFPRRPENQSINTNNKSTNETESPGASAKAQEDKLDRPAPSRARDDLLSESFFPTWKDGSAGEELDDTDDMQKKDPLAAQVWRLYSKTKKTLPNQERMENLTWRMMTINLRKQKQEEIARASKHNQTSTGPSGIAQLRKSNDQTAIDHSDAMNLDDFIFSDSISTPAGIVTSPSPELTKKEVDRSSNTVASAIPIKMRKESTQPQFSAPQSVPVPHHAPRSNEEFNYVQRHVRKTSIDERRARKRPADFSPQVNSIMIPNDPDHDDLQEYSLNQPHPPFSSHGVSSVPFQLDTFNMDNDPIITSAGPFQQNFNFSPSHSPLVTHGPFSSMYNNTSMTASSMNSNDYYSPPGTAYPSTVSTPQPIPEGQELYFQHGMSMRHQRPHTFSQGPSSLSNSMAPQYMYNGNGGSMFSAVTTSGPTNNSYASAGGFGMSQHIDPTQVFQRDHPVQSPGVHMGPENMFSFGGDSDNDDEESQAFADRTLMLQNDFARSPMDDQNMDMHGSGGLQWDASLSGQFNTQAARYPGGPPRKQVTIGGAEMVSSSLDWDGSAGSLGRHHGSTQSVSDNRSRSDRRQKIPRTASTPNAVLLGQNSMFDNSGQSGPNSPPDANNMSGFSSVAPSRPGSPGGSKHGSTTNLAAAGGQGDNGVPTTCTNCFTQTTPLWRRNPEGHPLCNACGLFLKLHGVVRPLSLKTDVIKKRNRGSGATLPIGASGGASTRASKKMGSLSSGPNTRKNSIVAATSMASAAPPTQVTTPTSSHGRNGNESASPPSIAGSLGNGGSTAGSTPTSYHGSAGSSSGTTGVSGGKGVVPIAAAPPKATPGPGAASTMPRSNAIPKRQRRHSKSVGASESMDIDSPEASTDSNEAAKSIGMGMMGTSNGAMANMGLANGFAMPGRSMMGQGGSVMQMGMGGPQHGLGMNGQTGPNGSGAGPQEWEWLTMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K0B0</accession>
    <name>A0A5N6K0B0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_007143</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K0B0"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000007">
        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="11">
        <location>
            <begin position="107"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="162"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="41"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="249"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8295225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="403" mass="40228" checksum="51A01C1DE01E4D8B" modified="2020-04-22" version="1">MVSSSLDWDGSAGSLGRHHGSTQSVSDNRSRSDRRQKIPRTASTPNAVLLGQNSMFDNSGQSGPNSPPDANNMSGFSSVAPSRPGSPGGSKHGSTTNLAAAGGQGDNGVPTTCTNCFTQTTPLWRRNPEGHPLCNACGLFLKLHGVVRPLSLKTDVIKKRNRGSGATLPIGASGGASTRASKKMGSLSSGPNTRKNSIVAATSMASAAPPTQVTTPTSSHGRNGNESASPPSIAGSLGNGGSTAGSTPTSYHGSAGSSSGTTGVSGGKGVVPIAAAPPKATPGPGAASTMPRSNAIPKRQRRHSKSVGASESMDIDSPEASTDSNEAAKSIGMGMMGTSNGAMANMGLANGFAMPGRSMMGQGGSVMQMGMGGPQHGLGMNGQTGPNGSGAGPQEWEWLTMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2E7</accession>
    <name>A0A5N6K2E7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_009075</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the SSK1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2E7"/>
    <dbReference type="OrthoDB" id="21225at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000146">
        <property type="entry name" value="Putative two-component response regulator SSK1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050956">
        <property type="entry name" value="2C_system_His_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719:SF28">
        <property type="entry name" value="PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="633"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="17"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="470"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="552"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="811"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="171"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="294"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="552"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="572"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="811"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="838"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00093463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8296305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="902" mass="99722" checksum="B91C48EEC0F326A4" modified="2020-04-22" version="1">MTIGDLKTRLRAKFYRRYSHTSSIGSAKDGEEKSLGFSESVEERSKSTTQSLRSKASFKLHRTPIYGGGGASTNGSSRNCSGSGSGSGSGSGNRNSIVESQSQSQSQSQSPKETSNFEEEKGEEGEGEEEIIPVHNNNDDGIAVQGRDEVEAELKLSFRNSTSSDLHQHLHLPSHSQSETETETESQSTSPITSTIPPKQVPFINSKLILEDENNKHDSISISTDFPTPNTDIPRVLEEEEEEEEEEEEEKEGQEQEKEKEKEEEEEEKEGVEKVEKDEIREESQSKSKEVKFDNSTQQSPISPKDTTGTHQPIPRKPELSRRQSLLPHQQTKLIKTLLETDLPAQTQVNLPTGVTVGIDYFSNHGPSTISATMVTRKIWVKRPGASATLVTIHEDDLVDDVRDMILKKYANSLGRNFDAPDVTLRIVPREQQRQERTLGPEEPMCRTLDAYFPGGQTVDEALVIDVPVKRTPKPSPRPNGHPVYYEEGRPTEAGSDYFPPMPIQVPSPGAPHNVPAQNNTQHTAPLLAHAMSPQKTSYHETKDRTNSYFLPNSYQYTHSQPPVINNEKSAAPPPPPLPTPPAPNQELAPQRVATPPPRVTSPRPTKRSKKKPGVDHPSLPAGMLNGAVPPINVLIVEDNIINLKLLEAFMKRLKVRWQTAMNGREAVNKWRGGGFHLVLMDIQLPIMSGLEATKEIRRLERLNSIGVFSSSASSTAPSEKELVDEEPAEGDKLPSTVLFKSPVIIVALTASSLQSDRHEALAAGCNDFLTKPVNFVWLERKVMEWGCMQALIDFDGWRKWKDFSSQQAAEKEAADSKKKDTQGLVKAKRKNRNSMGSVGGISGQGGSSTKLSQLGQLGDGVIGEGEAVMEEGRLRDLILERRVAWHSVYHDDELSICLDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K2F0</accession>
    <name>A0A5N6K2F0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K2F0"/>
    <dbReference type="OrthoDB" id="10329448at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="99" mass="11407" checksum="52200D9FE6AFCC46" modified="2020-04-22" version="1">MKDSLAYTRRLMIAGLFPLCSRIVHEISNSQNFRTSFLSITIYYSSLLSFTLHNSILLAILTCGMKWNGAGSKNETLIPIQCLIRRQAWCLSFDVYLYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4B1</accession>
    <name>A0A5N6K4B1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4B1"/>
    <dbReference type="OrthoDB" id="2107166at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045030">
        <property type="entry name" value="LYSM1-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932">
        <property type="entry name" value="LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932:SF31">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="32518" checksum="A76332E785287CBE" modified="2020-04-22" version="1">MNQEACCTCARLLGKITSTSSTVGSKPPPYSASTAESDSYTKSRGKSSDKRKNEGGIVSGKTATYTNEWEKNEEGGRQRLSSYDREPENWQFESEDSSREKEEGGWKAGGGRGRKENRREDRKLSCCGRIICGECIEGNERFGSHCPFCQVRSRDITSRDGPPSYESICPLSSPLTSLQTPPTIYAQNQTPLSPLNTPDTPETSDTIHHLAHPNDTPLSLSLRYKIPIEVLRKKNRITSDHLLLARKTILIPGEWYKGGESLSPRPVEGEEEERRKWVIRKFMVGCKVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4B6</accession>
    <name>A0A5N6K4B6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="1">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4B6"/>
    <dbReference type="OrthoDB" id="409122at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF19">
        <property type="entry name" value="SERINE PROTEASE AORO, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S53" evidence="2">
        <location>
            <begin position="1"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="285" mass="30675" checksum="9F63600ACB4CFBB4" modified="2020-04-22" version="1">MAKPEITHLLILFTQIHNLVDGTEHADLPIAYTKRQCNEFMKLGLQGHSILTASGDYGVGSFPGDGKVNGCLGPEGTIFNPQYPGNCPYITSVGGTMLYANQTVHDGESVMHVNLGGSASNFTSAGGFSNYFPIPSYQSSAVAKYFETAKLTYPYYSELEVNVNTTKGIYNRIGRGYPDISANGAEFRAHLDGSDYHWYGSSLASPLFASVFTLINEERLAIGKGPIGFVNPTLYKNAWALNDIVNGTNVGCGTEGFSAVEGWDPATGLGTPNYPKLKKLFLSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4B8</accession>
    <name>A0A5N6K4B8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pentacotripeptide-repeat region of PRORP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_002576</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4B8"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47941">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="457"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="593"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="48"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8297200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="661" mass="74101" checksum="A172E545661EC19F" modified="2020-04-22" version="1">MTLSLDVDYLNTAESMGTCHAEPGVHCRSSLVVDHHQSWHSKATFNSLIGTPQSSANEQHEQHHADSSRGFQGGETRNSQALPRRQPATRHATKDSVDALESMFEEALKQQSIGQPVHVAELSQQTSSSVKSYEYGEQFKKMLKEERPLGDCWSFFVEHFGPAAWRNGSIVRSTWPASLKSGVPSLLRLIRDKRKEQPFQVGLTTVKGQELLSELLMCWNIVCRRRSRRSQIEGYNKSSSDWSKLTRHTMHSIFLEKRNNGTQYAFSLLTPQFPPGQMYQLPTVALATLSLLLKLDSTGVGADTVQNAQPLISRFSSTIKACAMNLGDAAVFFRDMPESVVNLVRNDWSTIKEFNSKQKFPENFKATENERAHSLHKRVSDAFARRDVAQLDRLWSLAQKLPVYHPTAKDGSDSGYRPGHLTPAFYNYFILVFMSLKQQSRAIDVWNHMVKSNLTPDIGAWDALLNGCKMSRDPKALEQVWAMMIESGEAPDVNCWTTRISGLIHCYKADDGIRALDEMGRLWLAAIRKKYPNFKIENSKKSENSKKFKDVTDAVRPTIATINAAVSGLLKMQKIGAASRILAWADQWGIIPDVKTYNTLLGSIVRAGHIDKTPEILTVMEGQGVQADAATFVTVLEQTFADIDTLTPEEQIDAIYTSMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4B9</accession>
    <name>A0A5N6K4B9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4B9"/>
    <dbReference type="OrthoDB" id="5563016at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12751:SF18">
        <property type="entry name" value="PHOSPHATASE AND ACTIN REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12751">
        <property type="entry name" value="PHOSPHATASE AND ACTIN REGULATOR PHACTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="797"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="797"/>
            <end position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="912" mass="97369" checksum="63572E669013F891" modified="2020-04-22" version="1">MRHKSYTHVENCYKRKPKSNHERERERERKRLVNKNSRLSVFIEVLFIFYSIENYIDMAALVQTVPQQTTTVTMLQTRPSSASGPLQPSQNQAAFHQYPVNPQQRNNFHGLNNNNNNNNNNNNNNTAISNFRGHNAAAPIAPYTFTSTPGLSIGSQQTPNGAQSRPEQVRTSSAPIVPTIQGGPGNTSSRSRYPAAPSISTTSSSSSSELSQMPGTRDDSAITTARVATRAPRPNSTIITSHPQSLAPPMASPAKPAPDRYRRPAIRRAESSTSSQASGPSSSASTMPNVMQFYGASTQAVNAQALNLQASQPQNQPSATADDMQLNQRTTSEQAKRYRRRSIHTMDAPENSNAPNPGFLQQGSRQVSSASGRIDQQPEQHGQHPLRSSPVVTVRPATSHGRNDSTDSLKSTRSGHSRPNSSDKREATGVSMATSSPAHSSTSTVASSTTSNGKEQATSKNDQPRLVNIPVRASSTDAAKRLSSPSPLSKPATMGTESSVSKSKDSFASAVNAALQPTPSKPTSTQATASLNVPSPAAQHLAALNEKEGKKSKTSRLRRAFSFGSAAELRKVSAESHLVSRSGNDVLDRSKLRREKYQIEQDAEQDKIAQQQEAAGIGSNIYSGQGNFFTGSNDNLSISSTASSASVMIRKMGKGMKKSTRSLVGLFRPKSVIGVPAADAAVPEASRAQVSMVNVEAEREKVNINANAADAASGGTGFPRLERNSLDAAAVSSTASERLGSANTESSANRRSIVGGEKERAEVLAAVKKGILKRSGTGSGNSSPVILPVDGKAANFNLPQIPNVNDSPNSSAPSTPNDDQVHKQAVTLGGEDYFMSALKFRGDSKSVPGTPSGATKRNATFSPRIQFHDTWPSQEYDRRGDTATCNRLTPVLAQQIKEELNTFKMKVGNGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4E7</accession>
    <name>A0A5N6K4E7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_002606</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4E7"/>
    <dbReference type="OrthoDB" id="447251at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429:SF9">
        <property type="entry name" value="PAS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0157">Chromophore</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="491"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="86"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="797"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="184"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="214"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8297236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="835" mass="92123" checksum="8E9821A6EBC47C81" modified="2020-04-22" version="1">MSKKSVGTGDKPQPLHLQRQGRAYGSGIDARVYLGGNGNGNGTGIGSAAQLKSPPIFSLFPHPNQSTSTTSAEMNAQTLADRRAGMHPYGKIPTFTPPIKIDEAGPGEEGGAEVQDIPFYKPYRPGLGGSQVSGSQQGNRPRRLSLDRAFDPNSSRKASPAPETPAKVLQAQVEIPQRTSSLYNEEHRDPIEHQQENFEIPEREERVEIRDSKPSMLSSQQSMSSPSTGRSRSRAGSVSSYQTNATSLPPLQKTGVLEDGEILEPLNEDDVDPGSFDLVAATETGGRRFSLETRSEQLFSTEHLRIIFSDPSLLLRFTSFLGAQRPGSIPILIYYLDAVKALKAISYSNAIAEALEPIAGFDFTSTSASKTMSAELEEKAAKAFDVLVREDLPAYITWTYIQTVSISIQRRITGTLPAHLREASEGLAEVFCLTDPSRPDNPIVFASEEFHRTTQYGMSYVLGRNCRFLQGPKTNPFSVRRIREKIESGQEHCETFLNYRRDGSPFMNLLMCAPLCDSRGTIRYFIGAQVDISGLVKECSELESLQRLVTEYELAEEREAERAANPNAIPEALPALPPKDEFQELSEMLNMQELDTVRRWGGRMHKETEENHPDSNFQKGNWHKPRLHIGSISPDVMNPNPVAGRISGKLGGIYENYLLVRPYPSLRILFASPTLRVPGILQSLFMAKIGGSNRVREELTQALADGRGVTAKVRWVTKDDLEGRPRWIHCTPLIGSNGAIGVWMIVIVDDESLQQNNKKYRLAPAVDPRFGRSIPFTSKADSSAGSIRDFSLVNHGLSDNRAGAGHPPRTPRSPRSFEGDDGSLRSGSPYTLRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4E9</accession>
    <name>A0A5N6K4E9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">OBG-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_002585</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4E9"/>
    <dbReference type="OrthoDB" id="603at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903833">
        <property type="term" value="P:positive regulation of cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01896">
        <property type="entry name" value="DRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17230">
        <property type="entry name" value="TGS_DRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000003">
        <property type="entry name" value="Developmentally-regulated GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000740">
        <property type="entry name" value="Putative GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1070">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045001">
        <property type="entry name" value="DRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031662">
        <property type="entry name" value="GTP-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43127">
        <property type="entry name" value="DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16897">
        <property type="entry name" value="MMR_HSR1_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="64"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="290"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8297211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="40379" checksum="EA1F7729FCF90C66" modified="2020-04-22" version="1">MSTTADKIKQIEDEMAKTQKNKATSFHLGQLKAKLAKLKRELLTPSSSGGGAGVGFDVARTGVASVGFIGFPSVGKSTLMSKLTGQHSEAAAYEFTTLTTVPGQILYNGAKIQILDLPGIIQGAKDGKGRGRQVIAVAKTCHLIFIVLDVNKPLTDKKIIEDELEGFGIRINKSPPNIVFKKKDKGGINITNTVPMTHIDHDEIKAVMNEYKISSADIAIRCDATIDDLIDVLEAKSRSYIPVIYALNKIDAISIEELDLLYRIPNACPISSEHGWNVDELLEQMWEKLNLVRVYTKPKGKLPDYTAPVVLRSTRCTVEDFCNAIHKTIVDDFRVAIVYGKSVKHQPQRVGLSHELADEDIITIVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4J1</accession>
    <name>A0A5N6K4J1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4J1"/>
    <dbReference type="OrthoDB" id="21589at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039751">
        <property type="entry name" value="HERPUD1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12943:SF27">
        <property type="entry name" value="HOMOCYSTEINE-INDUCED ENDOPLASMIC RETICULUM PROTEIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12943">
        <property type="entry name" value="HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="508"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="541"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="666"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8297044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="767" mass="83561" checksum="E4E6FA374B1F9F03" modified="2020-04-22" version="1">MPVINILKRYWPTHFPISRTYFKLTGANTKVASPLTFPQLLATTTVEELKAKIRDVVESKPTDSAQRLIHRGRMLERGSQTMLEVFGQESLSTLDTQTLHLVLRPPPPEATPTTTVPLSQNAPLNTAPPRTLTPPPHLRGPQNLQQHRDFHHAAHTNHTPTERLLQLRRETERLQQEVEAGNRAYQSQVGRLMNLGNNVPAPPTVTRNPFVPPNSTPTSIQQLIAQHQQRRAAEGRHGVQDIGGQSNMFSALDEMYTGRSTAQYRTPDHSATYTRQGVGPNGERWQVTVNETTTTVPAFRSPVSQGHNSLQSPERASHGQYPTTAGATSGNPALDLQNLLRNVDRLRTPQTPAVPRPSSTPPSAQPATQNIPSSTPATTVTSAPSTPLPTVPPPAASVSVPYLTTTPSTSTRTTSSPSVEPVVYILTSPSGPRALLINNSETFYTPRASRTRQNVALGGRDLPGLPEYRNRNVQRARGAHGNRQRANEAAPVEFAPIHNRAQRPAVPIVLQLFNVLWLIVRLVGFVWFFTSGNSSWSRFFLMSGLAVVVFLINTGVLTGVFNGVAEQFWGPIRRHLENLIPLAGPDAALVPAANAEVVPQNGAAGAGAQPRLPNGQLDETQVAARLLELQRQRQAQPGWLITQIRRAEHAALLFVATREAEAAAQAERNRIEAENAETGVAANGGETASEANNGEHQPETAPGRGEASSENPRPNAEVQREVPPAQPLVFFGGFLSFFVFLKPEHGVQIERSSVQDSNDQMKPLIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K4J2</accession>
    <name>A0A5N6K4J2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K4J2"/>
    <dbReference type="OrthoDB" id="422106at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019416">
        <property type="entry name" value="NCBP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16291">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16291:SF0">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10309">
        <property type="entry name" value="NCBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="449" mass="50244" checksum="6304266CB47A4E80" modified="2020-04-22" version="1">MATDMDIDMDIDVGVIEELPIPDMVDIELIPDQPSGVQNGTSAPNDSSGPDAEKPTPEKVHIRGLDNLTTGDVKKFAQQYFPTGHIERVEWIDDSSLNLVYSNNEVAEEALRQFSTQELPEDISQLPILQSLNAKPFPDNEKISLQVRIAVVGDRKQRGARERSRFYLFNPEYDPAERRKREGGRRYRDRDDDGYRSRRYDEREQRNRQREDAEAGFDSSLYDDDEAALATRSGRIHRRSGSGSSGSDFKEQTDNRRGSGLRELFPDRGGSDGRLRDRSASPTRNDERASDYNRRRGNTAAAENRSKAQAIKARFRRETSTTKELFPSKLSTTHRSGVLDATDETADLFANRMPVPFMDGSSDVRPSNKRSLAERITSEQPQGFSIRGTAKPASTSGFSIKGLASENSATTMKELFPARAGGGNSGKELFSERLVGRGGRRQNAEDLFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6B2</accession>
    <name>A0A5N6K6B2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1753-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6B2"/>
    <dbReference type="OrthoDB" id="3338076at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070916">
        <property type="term" value="C:inositol phosphoceramide synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070917">
        <property type="term" value="F:inositol phosphoceramide synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006673">
        <property type="term" value="P:inositol phosphoceramide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013862">
        <property type="entry name" value="Kei1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28077">
        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE REGULATORY SUBUNIT KEI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28077:SF1">
        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE REGULATORY SUBUNIT KEI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08552">
        <property type="entry name" value="Kei1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8298125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="34542" checksum="2EB716FC19FFD301" modified="2020-04-22" version="1">MVFLPRWVRVPRPRTFLYVMTLRTGTEMISLSMIFNKVTGFYGLLAVLAGLKLSPLQLSMYIYSVAALALIAVLMPHIRKQTPFHCLALAWFYLFDTIINTAFTAAFAVTWLLAVSADQSNKGIPSAAPGSGTIDETAGFTSPKFNVSAVNVVASPGSGAGQDAVAYGTFAGATLEQSVGIEESVPSIIVVGILTLIRVYFILVVMAYARQVLRQNMYSASSTKLHLNIDGSTDARAENPFAATSPQGQGWMGKLGRLMVKVGEGYWLGGQVDEAWAKGLDGRFKTQRMFNGPPGTIERERRARSGTGPPVPVKGLGIGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6F0</accession>
    <name>A0A5N6K6F0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6F0"/>
    <dbReference type="OrthoDB" id="2163411at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="18846" checksum="44F5D0C2725E4F86" modified="2020-04-22" version="1">MQGGILRPPPNRRTGSLSSGSVLGLDDPQTPSMSSPHALASNQSEQLPFFKDYYSQDEIHPGDKVATLWAYQPRAGDEFTLERGDMLKVVGIWDDGWATGVMINERADEWDEKRKMQRDSGVSNTSGRREISPNVSGEIKAFPLVCVCLPDHWRRTIDGDGSTDSGGPPGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6F6</accession>
    <name>A0A5N6K6F6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001919</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6F6"/>
    <dbReference type="OrthoDB" id="4074350at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8298171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="98" mass="10485" checksum="0B23490CBF435ED0" modified="2020-04-22" version="1">MVSFVVKCALAQFPILLLVLGQFVGGVVAVKALSVAPSSAWFGNDGSWSAVSVRLGFPQQGVNLFPNTLSEEIWGVGPYGCEDDKKHLDNDTSFTSHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6G3</accession>
    <name>A0A5N6K6G3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6G3"/>
    <dbReference type="OrthoDB" id="2095648at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027040">
        <property type="entry name" value="PSMD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223:SF2">
        <property type="entry name" value="F-BOX AND WD DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11400)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="591"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="669"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="715"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="520"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="594"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="673"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8298175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="742" mass="80732" checksum="35038EB823966590" modified="2020-04-22" version="1">MTGSTLGVITAYSLGTGHSKAKVGSVMARWIPCPGVPIIAISVDDSYNNSRKASGRAWAVALNALGEVFYLTDIPTFINHPVDSSLDEDNLGRQAWISGRTVYWQVVEASRRVARDDPWQEAAVHGSYSPRSSCVSMNLSKQQVAAETREIEKFLRLRPLHFRTVCNGWDMRRRLEVDFSGDDGNGAGEGIFVISCGINPGEDAEIKRYTRCKVEKASLDGFTLPRTAPATPPMPSEPKLPSLFGDASKTKAEKIASLDSPIAPILPVARVEQTSANVEFGMDEEWRSSVLSLKSHPGVEITTSAIDLSTYALLTIDEDPLHTVNGKTNFTTFSGTPSGETSSTSIPGYRARYLAIGTKTGQVILWNMRGPQSENPQVVNELHPIRTIVTESPQISCLAISALFVVHGGNDGLVQAWDPLASSMQPVRTLHSRFSSRARRRLIQAEARIHGVGINLYAAGAIVLDPDPTILRGMVSLGTHLRYWHYSSSAADQFQTKKRRLRRGERGSNVATDRFSNTGRGALLSQIATEQEELAQEKKEKAKEAARLAGRFGVGFGGLSEEEALRYAEMVSAEALIEDEERRINEAGYFATDADNSPTKGQKSTGTVTSGASSQYTMPTSAAESEPNYDHDLEEAIRLSLMDGHAIGDNGYAPNHGDYDVNFTYKSKKTRRSASSSPSTSQASKNRFKSEASNSMAKHDELADDLEFALQLSLAEERSKQEAEAEELSGVGFTGKGKGRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6G8</accession>
    <name>A0A5N6K6G8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_001902</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6G8"/>
    <dbReference type="OrthoDB" id="5414787at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF131">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024965247" description="Xylanolytic transcriptional activator regulatory domain-containing protein" evidence="8">
        <location>
            <begin position="16"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="9">
        <location>
            <begin position="326"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="21"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="579"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="579"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="589"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8298146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="768" mass="86534" checksum="65B1E332BDFD7607" modified="2020-04-22" version="1">MILVLLMLLSRLVSSNCTECTYNHDPTKSIPKSRPSTTSPGARTPDLKNTPNLGNHVDIIQGNGGVGVVEELQSRVARLEELLQVSGRLSKIQRSPSQPPSTHRVSKRPNVATRLIPGLCTLIVKGSRSRYHGQNDRITLLNQFPEAKDFINKSASSNASIINLAKDVQYLQQKSQSHLMMRKETSNQESTAIISKLREFLPGKLVCDRLLKIYTENFEKSSRILHVPSFLRLYSHFWTSPDDKIFQSSAFLPQLTTILAICYKFLDGNSGFDDDQKTYLEMASLELVTAWIDTLSRKQAIDISTLQTETLLLLARQLQLLSPDKLWCATGALVRSAMVMGLHLRPTEFKKISPFHAELRRRIWVTIVQMDLQASIAASMPSIVPDIDFNQLAPANLNDSDFDESTDELPPSKPLYEWTDSLAQVTLAMSLAQQLKVVSLIRDVDPNMDLTEVVREGRKLEELLRCVPPPLKLDGTLQRSPSHLFDCVLLDIYLRRPFLNLYRLLLWEDRQDDPSFREMQQICLESSVAILSYQDYFDPSVADLDLLSTNLYWTMFQICCKNDVLAAVLSVCQYIKTSTSTSHSNESSPGFTQNRLPTTLPSPQMTNTQFSKARLTRIVESTLEGFTKRVGEFGSDLKDVLILSVVMQSVRANGTSDLKENLMHEGAKKALSACRQTLLQSFPNGEIQLPSNNPELNEESKNAIRATSTVDVSMPTVDQNIYTTQPPYIDTLATLTPDMNQFQGDIFDFADTGIFNVDNDWSYNEFWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6H3</accession>
    <name>A0A5N6K6H3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6H3"/>
    <dbReference type="OrthoDB" id="4152802at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="653" mass="72301" checksum="E1D425E6A1D17C96" modified="2020-04-22" version="1">MVPCIPSRPAVDASSSGRPLKRDSKRMRTGLKGNLQNPHSDISLPTVDSMRSSLSSNSIHQKSWRISALDSLAPRPTIRHSENPRYAPGVTGFGSDRSESQRRRIFDRIHIPEEVLKANKRIDELADDLDARELRELMERDQKRRERKKAAEKLKAERRVTRRQEKQKAEEAAAARYGTPPPDNMERGVLGREVVGLGIGTSAVTTSSKRRGSDTWDSGRGKRPAEAFLEDSPTHEASFVDENLTHSSERSEPFLGTAQVGTLGRANISPPASPRSHVRGPSSMSQVMNLDQSRTPSPAKKQRVETEPAKQPVEAKISQSWKSFFRRNKRLSRASTPSFSNTSRETVQTGPPPHLGHAPMVRQTSNIPKRTMSKFREDLPELPISPPDSRVQSPENDVVPPIRTDYLDKRASVRRSLEEQRRHDTPMSVMRLRDSTPTSAHRSTDVPSPEPPTILSQSLASIDSEGSWLSGKKTNSKRGSAQMTLAPLRDSASSLHQRYKELSESSEELGIAEDEYFSRITPGPEESMMKRQSTGLPMASSDEEDGGSIKQSPIYEEKTTWGAVARHPTVVHRERANSRSGLLDEAAEGSAGYRRSISYQAELVNEDSPGISRATSVDFGHVRKVSAGSARLLDMKPRASGEGTRMSVSHGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6H8</accession>
    <name>A0A5N6K6H8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome biogenesis protein NOP53</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_001880</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NOP53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6H8"/>
    <dbReference type="OrthoDB" id="5072at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011687">
        <property type="entry name" value="Nop53/GLTSCR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14211">
        <property type="entry name" value="GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14211:SF7">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NOP53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07767">
        <property type="entry name" value="Nop53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8298122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="81" mass="9739" checksum="C0A7ED847356FE69" modified="2020-04-22" version="1">MELRRRKLGKISLPERDLELVLPDELQESLRLLKPEGNLLKDRYRNMLVRGKVESRRPISFAKKAKRKATEKWTHKDFMLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6I1</accession>
    <name>A0A5N6K6I1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001909</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6I1"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8298156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="167" mass="18823" checksum="EFB18B9B83DA8B8D" modified="2020-04-22" version="1">MLSAGGPGSLNSLPKLNLPLSWLPVDIAATGVIDIALRKVCSSALVPPPAPHEAVVFHLVNDSTSVKWRHLLKWIGYDMKAKEFGEWLALAEEPEGLEDKHPARPLLGFWKAMDKRMKEDLTVKPSFSLLRTRQVSPTMNSFDGIDEQSAKKIWQWVQTLPKRWEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6J2</accession>
    <name>A0A5N6K6J2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytoplasmic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6J2"/>
    <dbReference type="OrthoDB" id="2589819at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025494">
        <property type="entry name" value="DUF4385"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14328">
        <property type="entry name" value="DUF4385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="27166" checksum="0475FC1D125F16E4" modified="2020-04-22" version="1">MPPRSSKFREDSIPCPGKFIRPAPTHYYTYRIQCGEQGVLTYEPYKSHLLPLWRFRTPSIAEKSSTALFDEFLRFYKEDDFVGMDMSRKFIQMGMTRSKRYANYKGGRKYDNGKNGEKVERDKSQGHEGQGDKLVASGIFKEMWQRCREHEGYKVLKERYQKELKNWIQVHESEEAKYIKQEEGEEELRDMPRRKPPGEAKEKVKIKEEDNTEEIPQKQRKKRKTNHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6M7</accession>
    <name>A0A5N6K6M7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MT-A70-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MT-A70-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6M7"/>
    <dbReference type="OrthoDB" id="61116at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007757">
        <property type="entry name" value="MT-A70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12829:SF4">
        <property type="entry name" value="N(6)-ADENINE-SPECIFIC METHYLTRANSFERASE METTL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12829">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05063">
        <property type="entry name" value="MT-A70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51143">
        <property type="entry name" value="MT_A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8298241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="52678" checksum="A6CC6D160E7918E2" modified="2020-04-22" version="1">MRRLIYKENYIINAPEKTIEELMLERYVQLALDEMKRAMKGQGTMCLDRVLGKNETQTRKRKSAELGKFQQTLMIESNNMLPKRVNIDESTATMPPKSKMIHGNIPEASFHVENRPDGFPRFHLIVMDPPWPNRSALRKDAYAIASGFLGIESLLKSLPCNHIESNGYMGIWITNKPAFRAMLLDPGGLFDQWGLELVEEWIWLKITTSGEPIYKIAGTWRKPWEILLVGRKKCFGKREFDFEKGPATEEEMGVEKQSGGDAASLAKQATINQEHGIRGSPTASPKPNKSSELSENTLVTIKRRIIFGVPDLHSRKPNLKYLFGQLLGLGDYMGLEIFARNLTAGWWGWGNEVMKFQMDRAWAEGEGEADAAEPVASAPVSNASPIRKPEEAVSSVDILDEGKIECRGEFLASECFEFLSTQGCYQVFFNISVLAKQSLLLYFFGLVCYLSKVEREEACAHTARYGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6N6</accession>
    <name>A0A5N6K6N6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6N6"/>
    <dbReference type="OrthoDB" id="66726at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22696">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22696:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="296" mass="32546" checksum="900305FB89336597" modified="2020-04-22" version="1">MAAPAMLDNSTRFDIASWTNWTAVNVTHYVPSARDLALAGPRMVMKLSSFFTVPETVDNILGIKMGGRIIPEATGAGMPDSMETITSAAVAGMRQLAEDRAETITEENLMANSKFSLESARSLGGLFTYATSKWALGCIVMAVVLNRTHIMASTRRPLEFTWKPRFLLRITPIILLLIQARWLLQSIQCQTSPDFGYLRWGNSSKSHNLMFTQNGGPLHTFSQAVLFGAKDSASCLAVSMIPNDYIVVNETDSEEAIPNTYDLSGSLSLLWPLFKTFSFSQFVETISCAVQGKLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8F1</accession>
    <name>A0A5N6K8F1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mannan polymerase complexes MNN9 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001129</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8F1"/>
    <dbReference type="OrthoDB" id="2405412at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF6">
        <property type="entry name" value="MANNAN POLYMERASE COMPLEXES SUBUNIT MNN9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8298993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="445" mass="50342" checksum="B7B7BDF09D3095E6" modified="2020-04-22" version="1">MFLLIKVNQSYYKISKYRDFEKGRRQDKRDCCPNLIFFTIRLRTRTGYIYITTSTKSNLSILRNSRIDKCALRTIPKPSIEDNISSSTTEPWAQSGLYGVRTRSLCFADSAASQLRRAGAASNPLSPPTSPFRKQNEATKSGKRIPPPVVHYHMNNVTSTADPLGNREAILILTPLARFYQGYWDNLLKLSYPHELITLAFIIPKNKEGNAATAALQEQVTKTQKSGPEKNRFASIIIERQDFDPPLASQTEAERHKFEHQKARRAAMSRARNSLLFTTLGPSVSWVLWLDSDVVETPPTLIQDLASHDKAIIVPNCFQRYYDAKDKRMAERPYDFNSWQDSDVARKLGESMGPDDILLEGYADMATYRTLMAYLTNDSGDVKTEVPLDGVGGTALMVKAERQKGLPEWQRDWVGTHLVSLITRSTTTTSERCPAHHFPTHLPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8F5</accession>
    <name>A0A5N6K8F5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_001140</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8F5"/>
    <dbReference type="OrthoDB" id="4151048at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052783">
        <property type="entry name" value="Metabolic/Drug-Res_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="170"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8299006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="456" mass="50598" checksum="EA631109D594E6C0" modified="2020-04-22" version="1">MTNSHDIKPPKVSKQGARKRKRESTSENSGLTSALESGKRNKRATRACERCRNKKIKCDIERDIACNACVDANVVCEAGNGKHTEDKKYPPGYTESLENTYQAMILVTDKLWRMVKNREEWTFAEPRMKDGGKGPVVIHDIAQALGCIRNAPGLPECFVEDAPALLNRLSSEEESKVKREAQTETTTSTEEASLESQSKLPQSSPRFQVASPTELPPPSYSSQFPQSPKVDQYIQTKPSIQLQCQSPDKFPPQAPMSKLASVDQSFDVSRPQHEPLTGSSNIHQSHKVNKLTSDFSGSMSWCNRINTTLDSRRTPGLTIQSQPYQYQEQQALSASSTVSPFSPTCHTNSPFQSTVSSFSPTYQANSPLSSETSYEGDSSLSSSPYLPNLQKDPYFPSVHHLDDAETQLFHDLNTPLGFCDSMFTFDVGFSDLSGSLFPVEDEPYSQDLLLKVTNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8J2</accession>
    <name>A0A5N6K8J2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Inositol monophosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_001173</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8J2"/>
    <dbReference type="OrthoDB" id="10254945at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854">
        <property type="entry name" value="INOSITOL MONOPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854:SF4">
        <property type="entry name" value="INOSITOL-1-MONOPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024869655" description="Inositol monophosphatase" evidence="5">
        <location>
            <begin position="22"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8299046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="10532" checksum="C1FE2D7530840CA1" modified="2020-04-22" version="1">MVHSLRCLGSAALNLAHVASGQQDVFWEGGCWAWDVAAGWCILVEAGGIMVGGNPGDWICEVDSRKYLAVRGAPSGQKDIVEELWRVIGDRKLVYES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8J4</accession>
    <name>A0A5N6K8J4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_001206</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8J4"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21608">
        <property type="entry name" value="RRM2_NsCP33_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000684">
        <property type="entry name" value="Putative glycine-rich RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048289">
        <property type="entry name" value="RRM2_NsCP33-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="33"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8299087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="200" mass="20769" checksum="116C51C5B0FC4C7D" modified="2020-04-22" version="1">MDSVPSRKKSQSFTFNSTYLTFSRSFREVIIMSKLFIGGLAWHTDENALREKFSEFGTVEEAVVVKDRDTGRSRGFGFVRYGQGNNPDSSPEADAEKAIQEMNSVEFDGRTIRVDKASERSGNDRAGGGGGFGGGRGGGGGYGGGRGGGGYGGGGGGYGGGRGYDNNSGGGYSGGGGYSGGKTCLDCHDSITIRTILMTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8K0</accession>
    <name>A0A5N6K8K0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF3328 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_001172</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8K0"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF6">
        <property type="entry name" value="OXIDASE USTYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8299043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="25903" checksum="1810AAF4B5E685D9" modified="2020-04-22" version="1">MSSYDDPEPPRWSKEDSEQSLLPNNEHLPSHPPSTPLRTKHYILLGISLLITSIISGLSVYILTSLTQLKSLQSADSHPDATLSTIDLTYQKLHTYTNFSSPDDSISAAAWNQYVINGFIALPHAWARDRGWPLGRDMPGDNSKGIYVVDGFHQLHCLMSLRAETLAILDGAPVQNLTHTKRHLDHCYDALRQAIICRADPTPLKGRKGGWILASEEESRQSWLGLLKDVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8K7</accession>
    <name>A0A5N6K8K7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycosyl hydrolase family 31 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8K7"/>
    <dbReference type="OrthoDB" id="1334205at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000057">
        <property type="entry name" value="Sugar hydrolase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051816">
        <property type="entry name" value="Glycosyl_Hydrolase_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43863">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03140)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43863:SF2">
        <property type="entry name" value="MALTASE-GLUCOAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="146" mass="16821" checksum="9AA96936FAFAEFF0" modified="2020-04-22" version="1">MCLEFPDDPTSWYLDRQFMFGDSLLVAPIFEESGDVEFYLPKGRWTNFFTHEVKNGPGWFTENHAFDTLPLYVRENTILVLGKSDQTKTVYDYSQDVEVRLYNTIKGAKARLVNSEGIDIGILEVDDEGKLKDQKILTGSWEVKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8L1</accession>
    <name>A0A5N6K8L1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycosyl hydrolase family 31 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8L1"/>
    <dbReference type="OrthoDB" id="1334205at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000057">
        <property type="entry name" value="Sugar hydrolase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051816">
        <property type="entry name" value="Glycosyl_Hydrolase_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43863">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03140)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43863:SF2">
        <property type="entry name" value="MALTASE-GLUCOAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="1">
        <location>
            <begin position="20"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="168" mass="19237" checksum="A4390EC35EB26076" modified="2020-04-22" version="1">MPYIFSQAQEAVELGIPLSLRAMCLEFPDDPTSWYLDRQFMFGDSLLVAPIFEESGDVEFYLPKGRWTNFFTHEVKNGPGWFTENHAFDTLPLYVRENTILVLGKSDQTKTVYDYSQDVEVRLYNTIKGAKARLVNSEGIDIGILEVDDEGKLKDQKILTGSWEVKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8M2</accession>
    <name>A0A5N6K8M2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001247</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8M2"/>
    <dbReference type="OrthoDB" id="2922289at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788:SF2">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="595" mass="69229" checksum="AD655890D9C2350A" modified="2020-04-22" version="1">MAVPAGNIQGFMENFWDTHGIPHPSSTPDLDVVRQEGRERSTEVLSHWNRLKNLLERHEEVIRKRWMKKSKVQKSKIILQAWPGLSATHRPEFKALIEEGSQARSEGTRFRDAYIWPYLNVEDLVRGKAFLLLINSRGRHPPHVFAHSDYKATYIGNVSGAVMPAFLDFHTMLLEGETAETYGRLVSWEEDEDVPMNTITGLAHRPRMGLKILEIQQRLLHFLVKCCEALLHDIYADLLISEASIKPEPPPLKDNSEWSTIASVAAEAPYRLPSQLDFNRLKDIVEARRMNAEDYIRDLREDPGYFGDVLGDVSEHRLVRLLDTFEIQSTLFDKPHFWEDIIENVVGDAYKALIVWDDIGQQLTRLASLQTKYASEMTPKKQLPPEYMQALLTLRYSLTQMQRKPLDDLKIAVYASPPFRSQFMREPEVSGSIKLRVQNKVEEDPMMWLLNTLWDDQQLMFLTLPNLVDEIENRIERDPSEKAKFSALVTRIFSDLGLMTRIYHELEIYLPWAAGYKSEFRKYKDEIEKDFPKRLSLLDSMDCNIEATGLVKFKSPDKGHFYYPSNQRRNKQNTESMRKAEHNLDVLWRKIDEVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8M8</accession>
    <name>A0A5N6K8M8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_001206</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8M8"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21608">
        <property type="entry name" value="RRM2_NsCP33_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000684">
        <property type="entry name" value="Putative glycine-rich RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048289">
        <property type="entry name" value="RRM2_NsCP33-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="132"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8299086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="299" mass="31758" checksum="B2F053295BB6D186" modified="2020-04-22" version="1">MGGAIINAVSFTSPALRLGKTSLPNNLTYQGILQPNKPPSLQLIPFLSILQPQPQSVPPTSTSTFIFKFQNVFRDFTFASLFKSPFLSNRTVLSVVRLIISFNHDRKKSQSFTFNSTYLTFSRSFREVIIMSKLFIGGLAWHTDENALREKFSEFGTVEEAVVVKDRDTGRSRGFGFVRYGQGNNPDSSPEADAEKAIQEMNSVEFDGRTIRVDKASERSGNDRAGGGGGFGGGRGGGGGYGGGRGGGGYGGGGGGYGGGRGYDNNSGGGYSGGGGYSGGKTCLDCHDSITIRTILMTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8N3</accession>
    <name>A0A5N6K8N3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8N3"/>
    <dbReference type="OrthoDB" id="4692089at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="73" mass="8542" checksum="530658BB7AD209EC" modified="2020-04-22" version="1">MSIWKRLRFRGTACAWYICELTVNSCLPNQLFMGNMPVQDSNNDFCLNLQINFCAIAVEFMRVHLCSFYEPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8Q9</accession>
    <name>A0A5N6K8Q9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8Q9"/>
    <dbReference type="OrthoDB" id="10259622at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="143" mass="16526" checksum="CA69575F482DE5E4" modified="2020-04-22" version="1">MQCLSLISKSFTGVRHFVEDLPVYCICNGHYNPDLLEYEHVCDNEACRTLYHSECLVEDTLTKRYYEEYPQDGTEPATNGKTKDKKKNIKSNRKLYSKKFKGEFISGNDEHTTPMIKITDLRSTPHTETMQRVACPKCSTLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K934</accession>
    <name>A0A5N6K934_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K934"/>
    <dbReference type="OrthoDB" id="3594623at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="144" mass="15738" checksum="B70D4DAAE073B7B5" modified="2020-04-22" version="1">MWERALIAKPKFEDTNEDSVDAEWGASEFSTNATSGAEPELLSPGHDNPVDEEEQATLEPGTLKWPENQPSPKCGNACSIRGTGKKLDAPDPAYAFRAVTLIWDTTPKSLTLALINTHNLDIQPRSLTTGNTARIIDNHHSTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAC7</accession>
    <name>A0A5N6KAC7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Spt20-like SEP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAC7"/>
    <dbReference type="OrthoDB" id="1932706at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046468">
        <property type="entry name" value="Spt20-like_SEP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12090">
        <property type="entry name" value="Spt20_SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spt20-like SEP" evidence="2">
        <location>
            <begin position="7"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="701" mass="77506" checksum="141994C5738CD1BF" modified="2020-04-22" version="1">MPAPGASNDSQRGKTAPPPAKSKVTMCVLFPTPLSTYIEIARNSTAPRTPDVDARQERSDGSISATVAQPTTPLGAVPPLPSLNMPPPAKRLKQAKFEFNCGNIYAAEAQIILATTAPLALEPANSAAECSRLLESLAHPMHSEKPPQPKSRKRTVAEMAADEALAADEQRYMLILDEQRSATVARGSGGTNVADGAGQAGGGFEARFETFNALANIKKEIAEKQIQKKIQDQENERKAKAEQEVQRSKELAENRQKEIERRQLVARQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEAQRRALAAQQQQQHPQAMQGIPPQSQGPHAHPSQPSGIVSNGMQAQRFHPQQNTQAQMSSPIVRNGTPHSQASPTVNNGIGHNSMQHSTSSMGGSPPRPGSVVQQNHPQMGAPTTHNMVPQRSQQSHAGTPRVHHATPNIQSTPLNRGLTPRMSQGSPLQGVMAQAPAMSQMGMNATQMHVQNISNLTPAQQQQYFMQLRPQHPQQQPMGTMPNGQPMTPQQIMQHQQMRQMQMQAHANNPNHQLAQGYQSQLAAMRQAGIPPNVNMNQQFMGNSMNMQNMQNLALQQQLQQQQLQQHQQQQQHPQHPQQQQPSAQQNHMIQQYMANNHAQTHQQMAQVFKQLVGREMATGAHPHGLPDALKKKLQVQAQSIVFQNIKTRMQAGIQPGMQMQNGMGMARQPGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KAC8</accession>
    <name>A0A5N6KAC8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KAC8"/>
    <dbReference type="OrthoDB" id="3800738at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="13"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="239" mass="27517" checksum="C99C74BDFA8D1984" modified="2020-04-22" version="1">MAETCAASRVFSIPELFNEILSYLPLSCLLVNVSLVCKSWAMALTSPGIERALYFRPAIHNGPTTWSSLLEEKFGVFFDFTYLSNGHVLCPGAFTALPWKRNHNAFKRADASWRDMLVFQPPCYSLEIERIKHERGGIQYKTTTIPCPDGLRMGMVWDIAQEWCLRRKHWLQMTGPEVEKTYQNPEVGYAERMIPKMILHWHITCPHRGSLASLGDDWASTGREEYDLFQLDHRLASHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCB3</accession>
    <name>A0A5N6KCB3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CST complex subunit Ten1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_002985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCB3"/>
    <dbReference type="OrthoDB" id="5275361at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990879">
        <property type="term" value="C:CST complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016233">
        <property type="term" value="P:telomere capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024222">
        <property type="entry name" value="Ten1_fungal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12658">
        <property type="entry name" value="Ten1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="14507" checksum="A1547E6D108B6EB7" modified="2020-04-22" version="1">MSKQYSGPVPSKLTLLADLQQFSPLDKVRFLGCVTGYDKKSSILTLEHNFPVDNGIKASVNVQLLLNILKSHETRIGEWVNIVGYIVDEDRQQGTKNRVPMTEISIQAIVLWSSGAIQLDAYERSLMAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCB8</accession>
    <name>A0A5N6KCB8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_002996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCB8"/>
    <dbReference type="OrthoDB" id="3643at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="84" mass="9737" checksum="8019DE46BFED2B70" modified="2020-04-22" version="1">MLVGRRWLCRLKWPKSLFFEGIETAALALAFTNQSLCIFQSSDLLYFEMQTVNNPPFLSGNKIPMLFYVLQPLIRQHFEPPSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCC2</accession>
    <name>A0A5N6KCC2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCC2"/>
    <dbReference type="OrthoDB" id="3555028at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="168" mass="18562" checksum="DF5594978E4880F7" modified="2020-04-22" version="1">MVGQETTMTEKLGKGKQRKGNRKRPAVKGSVEQPSTAVINTFQNTTAEDSLGVGLATVEIDQTPSTKPQKRSRKRAAVREESDESPVQQKRTNKSIATSLNAATSKPSPSERNKTNKYMGGSERLGDYLKQEDGHFENGMGWPQIEHYDLFGEQRDELDEFQLSGCGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCG0</accession>
    <name>A0A5N6KCG0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL15/eL18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_003004</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCG0"/>
    <dbReference type="OrthoDB" id="6353017at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000039">
        <property type="entry name" value="Ribosomal_eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021132">
        <property type="entry name" value="Ribosomal_eL18/eL18-A/B/_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17135">
        <property type="entry name" value="Ribosomal_L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01106">
        <property type="entry name" value="RIBOSOMAL_L18E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="4">
        <location>
            <begin position="2"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8301091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="262" mass="29263" checksum="09CE600AAAEED426" modified="2020-04-22" version="1">MGIDLDNHHVRNTHRKTPKSDNVYLKLLVKLYRFLARRTESSFNKVVLRRLFMSRINRPPVSISRIAAQTDKEEKRTVVVIGTVTDDNRLLTVPKVSVAALRFTATARARILAAGGEVLTLDQLALRAPTGSNTVLLRGPKNSREAVKHFGFGPHKHKVRNTVGNVVSRTNKSTTETICRVQGTQVREGSWTQKVQRFQGLNGLNWEVSLRTSGFTGLDTSRKGGETSIGYIRRAGSAVQSLAYEYYKKMMVSMQIGVVIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCG2</accession>
    <name>A0A5N6KCG2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCG2"/>
    <dbReference type="OrthoDB" id="3993201at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="296" mass="32744" checksum="BDA228CAD8DE5465" modified="2020-04-22" version="1">MSRVTPPVTKFTQIIRRSISTTSTVASPSAQLKTKGAKADLISKLSHERTITTTHRPLPPSIKTMPLMQGFRTSAPRPSPSASISTLDHLVLPRLPSASQAFTVRVPILPDNYSASQSIKESIDTAIPKQEIHIVSAQPEEAFAAVNVLTEVVGNEGEASMDLGEWVEGMRARGEEIRGKLVGRDSEQGVLAELWTSIQEDVFGSKGKDGLARFGRLELEFHTLMILRFHFLLFRLAVRGVCFYFLASLVWLAWLYGGGLYLLLLHLLVVPCEIFDSHFNTSYLVRTDLISNIILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KCG4</accession>
    <name>A0A5N6KCG4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_003001</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KCG4"/>
    <dbReference type="OrthoDB" id="5970at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12467">
        <property type="entry name" value="RRM_Srp1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000123">
        <property type="entry name" value="Pre-mRNA splicing factor (Srp1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034403">
        <property type="entry name" value="Srp1p_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050907">
        <property type="entry name" value="SRSF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23147">
        <property type="entry name" value="SERINE/ARGININE RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="6"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="89"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8301087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="245" mass="27969" checksum="84CCAEF1D276DF87" modified="2020-04-22" version="1">MSRGGTTLYVTGFGAGIRARDLAYEFERYGRLVRCDIPAPRTAASRLRFAFVEYESRRDADDAYHEMHNKRIGRDDLLKIEWARTPPSASWRFDTGEDRPGRRDGGRDSGRERGGRRSPRRRSNSPRRGRGDYSPPPMIGTAILRMNVMMSENPVPMEMTGKLPWILLHQRMMNWTPPSKQVLLRIRLAHGRKKFIIRFPETFRLEPGPGLATPTKLKPPSRSAACDCGHSFSWVVSIKNSKLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KED5</accession>
    <name>A0A5N6KED5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcium-binding protein NCS-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_003233</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the recoverin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KED5"/>
    <dbReference type="OrthoDB" id="202840at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000009">
        <property type="entry name" value="Visinin-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF178">
        <property type="entry name" value="NEUROCALCIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="144"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00071944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8301352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="190" mass="21914" checksum="8143CE36D90BCA0C" modified="2020-04-22" version="1">MGKSQSKLSAEQITELQKSTHFDKKELQQWYKGFLKDCPTGMLTKEEFQKIYRQFFPFGDPSSFADYVFNVFDSDKSGSIDFKEFICALSVTSRGKMEDKLDWAFQLYDIDGDGKISYEEMLAIVEAIYKMVGSMVKLPPDEDTPEKRVKKIFRMMDKDENGSLDMEEFKEGSKRDETIVSALSLYDGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KED6</accession>
    <name>A0A5N6KED6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_005509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KED6"/>
    <dbReference type="OrthoDB" id="5563754at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000203">
        <property type="entry name" value="PH domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058155">
        <property type="entry name" value="Skg3/CAF120-like_PH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25381">
        <property type="entry name" value="PH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="126"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="638"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="669"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="690"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="714" mass="79735" checksum="F4ADE43C393044CA" modified="2020-04-22" version="1">MGRNRVMSFMSQFRDRDSSSPTRTPLSSGRARSRTESYTKPVSQEKGKSQDTGKEPFPTSSFQMPSHQEYPSSETRDSSQPIRTRERASSKPTSMVTPQPPLMDVNQDTLPELQPIFTFLNSHSNKLYMEGYFLKLDDQNINGKANADRTWTECFAQLVGTILSLWDAAELDAAGQDGEVLPKFINLTDASIKMIESLPTRSPTEAPLQNVLSVSTAGKNRYLLHFNSHHSLVQWTAGIRLSMYEHVTLQEAYTGALIAGKGKLLNNIKPIMERSKLQTADWARVRFGAGTPWRRCWCVITPPDEKAFQRVQKQSQKKRSAYDRSRPPILKGDIKFYDSKKTRKVRPIATITDAYSAFAIYPQSKPLIDSSTLVKVEGSITIHSNPPLTSEGFVFVMPEVHPAVSGFEMMLRWLFPVYDTFGLYGRPGRLIAETNDTRSLMFAMPEHRRYGYLETLDVSSLISEQGSANWLESEWRRRMKDLTAKRMVTLKNNSQRNSQFGSRRSRNSMGNPRTRLQFDDASSVRSSPSIQFGRGAIAFQQPKSSGVAHHRSISETQPPSRQENQSPSVFDGAYDQAPAPFLHTLGDPISHDSSGLKHAQDVADSPERLSSEDEQAASAIPVRELQDLQTVTIPEPVAAPPAFKHAPGAKPPGKPLQSPDIRKANNRMSTATLSQLTGAAGAAASYQQGQERRGMNAQKHDRIEEDEDQGRGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KEG3</accession>
    <name>A0A5N6KEG3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003258</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KEG3"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140096">
        <property type="term" value="F:catalytic activity, acting on a protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990444">
        <property type="term" value="F:F-box domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062026">
        <property type="term" value="P:negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070372">
        <property type="term" value="P:regulation of ERK1 and ERK2 cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052449">
        <property type="entry name" value="STYX-Interacting_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588">
        <property type="entry name" value="SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588:SF1">
        <property type="entry name" value="SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="175"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8301382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="350" mass="39182" checksum="9152BC77DDBF8A1C" modified="2020-04-22" version="1">MPATMKSGTESGMGLRDFSTVEHGTTPTALYSWRPPSPPHIHIPPVLGTSAQIVLSEYRGLGDEQETREILSIITQGQNVSVERSDWKYEMRRHIQAILSFLYLGPSSGARDVETLKREGITMLLVIRDTMTAQARILSGAKVARQLGIEDGAVDVSGNMELIAAFPRAIQIINDHLIRVFRHRYPRGISSPSSAAMPKVLLFCESGNERSAAVAVAYLMATYELGLVQAIQYVQNQRFCVAFDDEMKHTLLNYHQLLEARRSVTQTLQADATVSLKSKRRLEADEDDVDMNHSQQDDLDRFGGRRMGVQHRSLTYFAWSFKFEILLYVTFVSAPHKGGSNNQNVRTPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGH2</accession>
    <name>A0A5N6KGH2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">UDP-glucose pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_006201</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a central role as a glucosyl donor in cellular metabolic pathways.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>alpha-D-glucose 1-phosphate + UTP + H(+) = UDP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3"/>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGH2"/>
    <dbReference type="OrthoDB" id="932129at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-alpha-D-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00897">
        <property type="entry name" value="UGPase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000001">
        <property type="entry name" value="UTP--glucose-1-phosphate uridylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000002">
        <property type="entry name" value="UTP--glucose-1-phosphate uridylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016267">
        <property type="entry name" value="UDPGP_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43511">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000806">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000806-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8302873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="440" mass="48947" checksum="18719B3BD2BBC61F" modified="2020-04-22" version="1">MIMILSNAKSSDWDRIAPPAQGQVVDYNELANSESVGFLNKLAVLKLNGGLGTSMGCVGPKSVIEVRDGMSFLDLSVRQIEYLNRTYNVNVPFVLMNSFNTDDDTSNIIKKYEGHNIDILTFNQSRYPRILKDSLLPAPKSFDSPISDWYPPGHGDVFESLYNSGILDTLIKRGVEIVFLSNVDNLGAVVDLRILQHMVETKAEYIMELTDKTKADVKGGTIIDYEGSVRLLEIAQVPKEHTNEFKSIKKFKYFNTNNIWLNLQAVKRIVENNELEMEIIPNNKSIPADKKGESDVSIVQLETAVGAAIRHFHNAHGVNVPRRRFLPVKTCSDLMLVKSDLYSLKHGQLQIDPSRFGPAPLIKLGNDFKKVSDFQKRIGSIPRILELDHLTITGAVNLGRGVTLKGTVIIVATEGQTIDIPPGSILENVVVQGSLRLLEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGH6</accession>
    <name>A0A5N6KGH6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGH6"/>
    <dbReference type="OrthoDB" id="73919at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47800">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47800:SF5">
        <property type="entry name" value="FER-1-LIKE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="496" mass="56187" checksum="417A1DBCB5F7A4A1" modified="2020-04-22" version="1">MQFLKMVHFDEGGRIFTYVLSLDGLLRFTETGKEFGIDLLSKHTMHSNVNIYIACSGEFFIRRLKHPHQSTDDPSQSSHPTEDLPGGPPHTTPPKDPSHYELVIDNDSGTYRPKGELLPLLKEFLNENFPGLHIVTKECTDDHLQKMKQGQRERKKKEGNEINMVQNSDDEISSSDEEDLNDLVGGSGRKGKSKRERLINGLEDPSQAIKDARKDFIPGRERVQREENEDIPETATLDALPLAMMAKLGVLLENAVGEYQGKLTSTPSSPFLSFPFLSFLLFCFVLFCFVLLLLFSLPPSLSLAFAFALFFSFMIPSTTIGLVYFSFYFYTNNYNWDLRGGIGLHGMVGRTDGRMDGWVDGCLKLEWGGNGLGDDSFSNYCIALKFGTNLCGVVYVDIFYFLTGSSACIFLKPVVEKCHSHACSATHRHFNNVFLSIAYQKILCYHWLAYANCNRLSQKYYRSTYYSFIKIPKPMMILVPTIAKSHYLRKNKEVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGH7</accession>
    <name>A0A5N6KGH7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGH7"/>
    <dbReference type="OrthoDB" id="10001928at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000142">
        <property type="entry name" value="Regulatory protein ral2, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503">
        <property type="entry name" value="MCG48959-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503:SF2">
        <property type="entry name" value="NEGATIVE REGULATOR OF SPORULATION MDS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="41961" checksum="F8816F5DD9621B03" modified="2020-04-22" version="1">MVELEAFGLYDNPRKAAPMSGFVSASSPFTNPLLNINSKAGWNTGGRTLSKAAEELGQSALALRELADMDILCVGGERIPVNSRIIARRWGPYFVQLLREGTATQDGNDAATLRQESVFRHNPSRNSSVTITPTLGGQSSSLSTSSTLNSSDSAALALPPDSGSLPPNSRPRTLYLPHTQLTLQALLHFLYTSSLPPKNSTLCTPQILCSLLQLARPYKIDGLLEAVVERLHGVLDSRNAAAVFNASAMAAGGGRSTSTASDIADPWSLNRLSNGAETLMQLGLDNEISAHGQQSLRINTSVGDLGTGQGGRGQDDEESMSATSSAASDVSSSDLGRSVSASDSGRVNSAGEIWRGDISAVIGLQKRGLRGLMEGRRLRERGASVSAASSQRVGLGIANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGI2</accession>
    <name>A0A5N6KGI2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sterol regulatory element-binding protein 1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGI2"/>
    <dbReference type="OrthoDB" id="2133190at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032933">
        <property type="term" value="P:SREBP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019006">
        <property type="entry name" value="Sre1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09427">
        <property type="entry name" value="DUF2014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sterol regulatory element-binding protein 1 C-terminal" evidence="1">
        <location>
            <begin position="71"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="522" mass="56852" checksum="8E050E5FB4FC5C69" modified="2020-04-22" version="1">MALPAQFLRTVSRGVHSALEVNFQGYHLAAHQTVHYLQCSLALGLLLYIFLPSLFRPKPNSKDSKSAHLAAAPSLASSIQVRRQAWLTAIQTVWVPRHNFFLEAAALCMKVGKYTCRNVVGPSLYSFLTGATEEQEVARIKAWSIALDAQLTGGDVEVSKSRLTLTLLASGTLPDTPARLMLKALHIRVLLWEPKSNGFSGSNIVRNFAQEMARWKWNEAKQMQQILSQSKEQHDELPEYLATLLEKNCDDVLVDAVVQRAYNLAWNLPTTNNTHVNCGMDRVVDDFAIRSPLDAVAAWWSSLTLHTALAKSLEAKDGDVESYKTVVDGIKMAIQTAPPGSGAQIRALAARAVLVKEQRGHSIAIALKAVGAGQQKMPAASNVNIKTSISNLPDIQSSVHCAMALAYLERFPMPAHPENAVRIIDSIVPSNLTLLGFTSLFKLLERMHEHTSISSACALSVEKFAGGLRIWIGGPKGAKSGLDTELKNEMVDKFKAIIAQAVGMENDAGYGTMSGDDDSEGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGI5</accession>
    <name>A0A5N6KGI5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ADP-ribosylation factor GTPase-activating protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_006131</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase-activating protein for the ADP ribosylation factor family.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGI5"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07608">
        <property type="entry name" value="BAR_ArfGAP_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000051">
        <property type="entry name" value="ARF GTPase activator (Csx2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000252">
        <property type="entry name" value="ARF GTPase activator (Csx2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000017">
        <property type="entry name" value="ARF GTPase activator (Csx2), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045258">
        <property type="entry name" value="ACAP1/2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180:SF160">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180">
        <property type="entry name" value="CENTAURIN/ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="7">
        <location>
            <begin position="649"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="domain" description="Arf-GAP" evidence="8">
        <location>
            <begin position="835"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="214"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="552"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="606"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="790"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1067"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="225"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="558"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="576"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1068"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1088"/>
            <end position="1097"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8302785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1116" mass="123691" checksum="A2CF4DF51589E94B" modified="2020-04-22" version="1">MGNVSSRPDDGSPLYLRDQSRLTISSLSITNQRRKTLLNVVPNGFPATRVSAIRDLGDSSVVEYIQDPDTLPGAAPNFLIKVNNDEELIFNFTFIIRQSQGFLPATSGAKDAVGMMDTVINGLTYVSASTARENANVQLVGDYSTGGSQSVSFEWSWKWRPPKPVEDRGGGWRNNCSFLEYDQRAHRLNTLASFSFWVSSKALTATLPSSADKALDPQPLSMPGSPSPPFHLVPPPKLRLPSSQSLDSRVSGQEQSYEDAPSSPNPLSLDLVVPQIHMADVPKVDVSCQRPGEDMSATEDGPLFRATMKALEQKTGNMRTRMKKVLRKAEAAQIAQINCNDAIGGFMEALREASNSNANAVQPALDHYFDKIAREILQYERQNALNLEKVIIEPLTKLYTLDIKQAESKKRDFEEESKDYYAYVSRYLGQRQDSLKQKKRAESDTKYQTKRRNFELKRFDYSSFMQDLHGGRKEQEVLSHLTKYADAQTRSYLAAAKKVEQMLPQLEALSAEVQDADKEFQYQRTEREEKRRNLEKSTVTYVEPETVPAVSVEAVVPGTSSSGNGTSTSDSELNRSDSTGYQLRPIPTNSTTATVTNGGMTEFTRSPGSLSSAAGGTVGSPVTNPRFRGIRDLEEKDHSQITASEKLGTQRKEGLLWALSRPGSHVDPRGLNKQAWHKFWIVLDAGKLSEYSNWKQRLDLHMEPIDLRMASVREARDAERRFCFEVITPQYKRVYQATSEEDMKNWISAINNALQSAVEGRGMKDYPTVAPQPEAHSIRRDIGSILTGKSSSMNHGHSSNHNNTSNTNNVFRRTTVGARPAYGRSTSSSFDENPDKLLQLLRETDQGNCWCADCGSGIKTEWVSINLAIILCIECSGIHRSLGTHISKVRSLTLDINSFTTDIVELLLLVGNRVSNMVWEARLDLATKPTPQATREQRLKFITAKYVDRAFVEPISSTLSRYATADETLLAAVKKNDVQQVIYALALKANPNVTDKSRGTHSVFLALAAADPASPAQVTPSTRVEPPAKIVPFPIAEMLVQHGAEIPTALPAFPLSRSATLYIEQKTQRGGSTSDTIGALPTTMTPQEKLKEREARLQKRVSAGGRLAKTPIQERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGJ6</accession>
    <name>A0A5N6KGJ6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Phosphomannomutase</fullName>
            <ecNumber evidence="5 12">5.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">EYC80_006063</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>alpha-D-mannose 1-phosphate = D-mannose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11140"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="EC" id="5.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the eukaryotic PMM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.8" evidence="5 12"/>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGJ6"/>
    <dbReference type="OrthoDB" id="2419400at2759"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00424"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02585">
        <property type="entry name" value="HAD_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1240.20:FF:000001">
        <property type="entry name" value="Phosphomannomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005002">
        <property type="entry name" value="PMM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043169">
        <property type="entry name" value="PMM_cap"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466">
        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466:SF0">
        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03332">
        <property type="entry name" value="PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="530"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="453"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAB8302701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="608" mass="69221" checksum="A16744FCFDC5749D" modified="2020-04-22" version="1">MELSLPARLSASAEMLSLLAALRQKCAIGYVGGSDMAKQQEQLGTAEIPVTSLFDFCFAENGLTAFKSGVPLQSNSFIKWIGEARYKELVRFILHYVADLDIPVKRGTFVEFRNGMINVSPIGRNASVVERNEYEVYDKEHHIREKFIEALKEKFSGLDLTYSIGGQISFDVFPTGWDKTYCLQHLENDAKRPGGIEYTTIHFFGDKTYKGGNDYEIYEDKRTIGHSVKNPDDTMRDIRQLIRGGNRERLISNKSQSILIVSDHQSSRKISLEVRYVCVNYWTIYLIKHRSIPLFFSFLFFSFLPFQVHPIKLNNLIIQKRNNHVLPPSNNTRSIIPLIPRTIQLKIHTPTPRNPTPIRTRPGIQRRKINVPRVCRRTGIAVPHKRKMIRHAPAEHQPVAYLVPSDRLRIALLTLRVPGDIDRYLDVVWWAVAGGLGGKSRIAAVDAAAVAGREVSEGKGREGKGREGKGREGKGRGTSELYQRKLVTSQVGITSHSGGGVMDWRGWRCAMQDTVFKRREKRRRKKRGRALVYMVRCGWMFGTQLIIAQFLYTMMLVSRSCVAHGERGVHVKYEDAVRYYVKSWMGERFHGQLLGGALRIDVADMQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGK2</accession>
    <name>A0A5N6KGK2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006169</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGK2"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="95" mass="10509" checksum="FCBC7BB13B1749F3" modified="2020-04-22" version="1">MELAMDLPRSHEARRVAVAACVVPYAYSVTKSSTCYGRALFHLEALVEESADFAADLFRAYTRAVRGALGAHTIVDPLTMRAYRITTGIETAWEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGK3</accession>
    <name>A0A5N6KGK3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CLIP1 zinc knuckle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGK3"/>
    <dbReference type="OrthoDB" id="2130750at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="50117" checksum="8D5399B3C7E642DA" modified="2020-04-22" version="1">MDSSVQSLMENTNENTSGHRHSRGSMEDKDASQLRATIREKNEKIAMLTAEFDQHRADFRSTIDTLEMAGVETERVYEERLSHLVMELKLMQENNHDVKHVAVQLKQLEELVQELEEGLEDARRGEAEARGEVEFLRGEVERTRSELRREREKTAEALNNAKPHASIDAGVHSQEIAQRDDEIRGLKAIIHSLSRDIITDESSSDHDKTPGTSRPGLNRSHTESASVSEEERRTRENLEREVSELRAVVESKANKEEQMERELEGLRRGSISNPATHRTSAVSSPTVTQDRNTSRDTKDAVGSWRDREGASDAHHDNLETMPENESFSSEDFCELCDTSGHDVLHCPMFGGDSRSSSKNESSPQQKTGKDVVMEGLKISPNSSPEKYKPAPLAPAKKASDASPIKTAFNPMEPGAAPGKESGVINMDKWCGVCERDGHDSIDCPFEDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGK5</accession>
    <name>A0A5N6KGK5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">POLO box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_006069</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGK5"/>
    <dbReference type="OrthoDB" id="408964at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13118">
        <property type="entry name" value="POLO_box_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1120.30:FF:000004">
        <property type="entry name" value="Serine/threonine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.30">
        <property type="entry name" value="POLO box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033701">
        <property type="entry name" value="POLO_box_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000959">
        <property type="entry name" value="POLO_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036947">
        <property type="entry name" value="POLO_box_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00659">
        <property type="entry name" value="POLO_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82615">
        <property type="entry name" value="Polo-box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLO box" evidence="3">
        <location>
            <begin position="475"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8302711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="655" mass="73908" checksum="065352BEF32618DE" modified="2020-04-22" version="1">MPQVEEMSADLLEDPPRPDQFPSVVIKPGRPNPYARSLKKLCIKCEVGPWTPKKQYTSLYKECALEEKAGLTPHVPLVEGVVYRPYAEWVREQEQQGAEEKAATELEASSTVVESLIADIAGSTLGPLAKKPISQRTISQRAVSQSFAAQQRVKDQSSNSATIRGVLPRRPTQRETKVRDPPSNTTTEIKPRGILKAKAIPSVPQISSEAEGRLAANLVDELQKADEERKSQELKKQQSTKNVVSLFGPQEKLEWLPGSKPDHILEALQRLQVELDRALNSRSIAATPKSRPATPAIVVKWVDYTNKYGLGYILSNGSVGCVFRETPAGSPESEDNVIAPSCIVIRDGERHLANRTNKSYVNRHQIVPISGPNVEFYESKGERGMLRGSVPAKTYRVAENEGRPGRLPLGVDSFDNRKREKICLWKKFGNYMFAYGRDAEYPYESWTAGQNPEATVNSTVITFYQRWGDVGCWGFSDGHFQFNFPDHTKVVLSADGFWCDFYHLSFECARELTEKGTLPTTALDERQHLSYPLQTLLNFMAKPSRAAKTTLRKRPEIDPMIQGLPQANDFRRKVEFIRCAVKEWVHNGGLGISDMEPKTRLRWMGYREVYDDKKLKHVWTTVGGRKGDERRVAWYDPRKPQEVIYDAEVNGVMVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KH05</accession>
    <name>A0A5N6KH05_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KH05"/>
    <dbReference type="OrthoDB" id="3853857at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF108">
        <property type="entry name" value="DAGKC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="465" mass="50294" checksum="B6E318B71BD7B1AB" modified="2020-04-22" version="1">MAYSTPSSNSDATYSSPDNDTEVTESSATPYAYLANDLTWSGALGRDGGASGGKIKGEDVICVIENEGRNHTPGYTIFSLSPIDGGVKKLAFELKITSATNLPQEGLESYLVKSLPTYLRSTETQIYVLISTLSGTGLAPDFYDTVLHRILDSIGLPETSYTLIKTDNADSVKEFASSIVLDGANKGIQQSILMLSGDGGMVDTINGLLESGEKSSSYVKPTLSQLPLGLRTLLHGTPLPLPIFSVRFSSGARTITNEGQTETPLTNNVVYGAVVASYGLHATLVADSDTVEYRKHGDKRFHLVAGDLLYPKDGALPHAYKASVTLTRSNGTEERISRKEHGYILSSLVSKLERTFTISPASQPLDGQLRVVHFGAATGKQTMRVMEEAYKDGNHIGMKWDEDGQKGEVGYESIEKLRIDFEEPGEGFKWRRCCVDGLIVGVEEGGWMEVERLKGEGTVDVVVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIL0</accession>
    <name>A0A5N6KIL0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome c oxidase copper chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_005010</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COX17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIL0"/>
    <dbReference type="OrthoDB" id="1915887at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016531">
        <property type="term" value="F:copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1130:FF:000004">
        <property type="entry name" value="Cytochrome c oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007745">
        <property type="entry name" value="Cyt_c_oxidase_Cu-chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05051">
        <property type="entry name" value="COX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 8" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR607745-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8303613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="15061" checksum="205451F2E0DA3AE5" modified="2020-04-22" version="1">MDAATIFWWWGAAAALQGQEKLNLELMVNKSDKLFYGRRVPIRNYVVILVKDDIRHMNMSSSAINMPASVTSANMAADLKPAGDASSKPKPCCVCKEEKAARDECMLFSTAKDPQVACASMVDRYKSCMAGFGFNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIN3</accession>
    <name>A0A5N6KIN3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004938</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIN3"/>
    <dbReference type="OrthoDB" id="10254945at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="519" mass="59462" checksum="68ED6210489AFA20" modified="2020-04-22" version="1">MATKKYGNATSMIFNVKRDKYGLTRVFKPTSAPTPTASGWSPTGHLPPGANLETIQEEKLIEEFQRHELYNFTVRELVDLDVISSRILEEGNLANPIHPIFSRNVWEQVGQRPYDWHIQTPELTARGDMCIMHNPIISEAMTPVLTLASAFLSRMHAVPFFDALLLGPRRPMEQNSSTTRLPAGLCTFWRRTPGQTNANDFAECKKQFSVALRRLHKTIRWGFAPGTRMPWDVVPLKGSGCLGITHEGKNSDNRDTIWVFIDQKLCDLLLRDDLTSAEKAGAQYLLAIVMCHELTHALWFCIQDHKLNKHYEPFFEDAPQCELGFEMENSVFGGLIEALIPTPAAPFAYAMGCTYPNYSSLDQRVPRTIVMDKAKAYYDQSFQYFIPIQTFEDIRKQTYWDTAIRQFGFTVIHTRSIKHGWKVDFAPDWKDVNEEGRPSYKASLFARINYLQGIPLTGNGEIRVLVSKYDGKQLPPKKKASFKFIEDLIVSARQEEEFYDFTQDQEDKLWQGQDSSRPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJ01</accession>
    <name>A0A5N6KJ01_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_005034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJ01"/>
    <dbReference type="OrthoDB" id="428260at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF17">
        <property type="entry name" value="(LOVD), PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8303638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="20280" checksum="2E0271366D5EF285" modified="2020-04-22" version="1">MSTREGGVNQHGTTTNPEGKAKYTSKVIFDPGTQDCHGGSGTFGSPIDYFKCLQSICANDGKLLKSETIDEMFRPQLSEASRRGLMETLSVPEVNDGMEAFPMGLEADWGLGGIMNLEDIGSRSKGSIAWGGYPNLHWWIDRKSGICGMWGSQLEPPGDPKINQLFHTFEEEIYRRASASREKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJ07</accession>
    <name>A0A5N6KJ07_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Myocyte-specific enhancer factor 2d</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_005061</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJ07"/>
    <dbReference type="OrthoDB" id="128867at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052254">
        <property type="entry name" value="CUL4-DDB1_E3_ligase_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472:SF1">
        <property type="entry name" value="DDB1 AND CUL4 ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8303667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="57101" checksum="F3998894C88F3ED5" modified="2020-04-22" version="1">MSQVPEIPGYYYDNEKRKYFKIQANAPSGSAYSSQDVKRRKIDDDNKKSQSLKVQRNIGRIRRARILEAPIAGGFLSVRFGQYTLHDVSTSVYAQNIIKTGDAGLTRCGGKHLFVVMPQKSRSPIRFSMAQGHKIGHFAVDWRAMAHGQQVENVFENNIRNLETSVPYFQAVEYDNLNHLNSQITSISVNETTEHIATTWSGAPADRGIAISRCPEMIAPHNHSSQLTNVFLGPGTTRGNVDILSSTPAPSHSQNMFAIGSSKGILVVDKNLDMSWIQRQSSNNAFGTSRTHPRDVFSLAYLPNHKDILLSGERSGMLNIIDLRLPQFGAAAEKIQYTSCVAHIKPLDEHRILVAGCASDLSQYDRRFIKRNTDRSIFSTVRTASERPYLTYPGYRNNGFIGIPLDVDMELGIIAAADEPSVITLFSLHGGQVLSGFNFRSNMECIKFVPDEWGKPKSLWATLTDNLVRLSFDKEETPSGLIDSHNSNQYRIHTNPNTVATRHFATGNQTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJ45</accession>
    <name>A0A5N6KJ45_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">coproporphyrinogen oxidase</fullName>
            <ecNumber evidence="4">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_005169</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="4"/>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJ45"/>
    <dbReference type="OrthoDB" id="15318at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="entry name" value="Coproporphyrinogen III oxidase, aerobic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755:SF0">
        <property type="entry name" value="OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="Coproporphyrinogen III oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8303794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="149" mass="17329" checksum="5077A5A4D45CBB49" modified="2020-04-22" version="1">MLFISTRRSRKHATTMIKTTILDSRNGATTISPTNIEGKLGDQENTFAFAQSCLKAFLPSYLPIINKRKDMPYTEKEKEWQQIRRGRYVEFNLVHDRGTAFGLNTPSARVESILMSLPLTASWRYMYEPEKGSREQRLVDVLREPKEWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJ47</accession>
    <name>A0A5N6KJ47_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA repair metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJ47"/>
    <dbReference type="OrthoDB" id="262529at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16273">
        <property type="entry name" value="SNM1A-1C-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000038">
        <property type="entry name" value="DNA cross-link repair protein pso2/snm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF6">
        <property type="entry name" value="DNA CROSS-LINK REPAIR 1A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="703"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="823" mass="91487" checksum="B39A23C20F67A8D7" modified="2020-04-22" version="1">MAPRNTNKPTTPQSASKSIASAFSKQPTKKIAISRTPVRANGNIMNFFKKVDNPFKDDDSLFVAQRSGTAVEPPPEIADDDLYGVNDEGYDEAERSIKKRKLSDKTNTEDLSIPTPPLAENQIPIAKGKSSRKAPRRSGPFLDDSDSDAESMEAILTAQAKTQIERKQPENSTIKGIAGLGTKQEHTVEKKSDMISTESILPLGSSVFKLKRRVPIKRAQAEWEAKQARNAKAMSSPDEKPEYRGGSRYFDNWESEKFETESEYDDEKTSNGYKNSDSKPKGKGKRKRKSNSHPETGTLKEENTSTDTWEEFEGMGEFPDEDVDGEEFMERKFMEENNLEADNEAQTEEDSFNGFDDDLGPSTNLEEERISTCPMCDANLSNITSKQVSMHVNACLDGNPIPLPTKTKAKPKVHTESSEAKLMPDDARSRYSKKAAIPRPGQANPIELGNDGGSAFSRIMSGNIEDAAWASAADKEKSSRGKPAYQRTCPFYKIMPGLFICVDAFRYGAVKDCKAYFLSHFHSDHYVGLTSTWSHGPIYCSKITGNLVIQQLKVDAKWVVCIDFDSKVQVPDTKGVSVTMIPANHCPGSSLFLFEKSIGRGSNPKIQRILHCGDFRACPAHIAHPLLMPNVVDSVNGKTKQQKIDICYLDTTYLNPKFAFPSQDDVVKACADMCVSLSKENAEEDDAWETVKRERAGAKMTKFIKSASKTETEDSNTTEAPSKDKKKARGRLLVVCGTYSIGKERIVLGIARALDCKIYAIPSKMRICAALEDPELTSRLTSDPLEAQIHMQMIMDLRPETLQDYLSVYKIHHGRLGATERKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKR4</accession>
    <name>A0A5N6KKR4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_003788</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKR4"/>
    <dbReference type="OrthoDB" id="5331848at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF146">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="62"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8304383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="385" mass="43177" checksum="2A750F7617E1C906" modified="2020-04-22" version="1">MAHQDHCEGSTGKYSLMMICLISFSYKFRPLSIELIPTYIFGSGDMPIGEAPQAFAFLIVMARFYARIMIKGLGKDDWVMLVTLGLFISYGALMTYEWKLGGFRHLYYLLPAQVMKVAKINYIIQVNIVFAFITGKVAVGFLVLRIMSGDSTTWRRWLVYGAMGLTALINSLDCIFTYVQCSPPRALWNPSIPHTCWDPNIQTRFAMFTAAENCLADIVLALVPASVIMNLNMEMKKRVSLTILLGLGLIAAICCIVKTTFLGSLNAHSDLTWKTYDLLVWSGSELFVIIVCGSIPPLKPYWDRYVSGQNPTSYGSGPANSYNSQLSSFRARRKSRMLYMKQSFGEANSSSDQVYPQILHGDKFIQRTTDIEIHSMRVPSGHSMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKS0</accession>
    <name>A0A5N6KKS0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_005167</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Vacuole membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ATG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKS0"/>
    <dbReference type="OrthoDB" id="6738456at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048646">
        <property type="term" value="P:anatomical structure formation involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16128">
        <property type="entry name" value="Ubl_ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000010">
        <property type="entry name" value="Autophagy-related protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="lipid moiety-binding region" description="Phosphatidylserine amidated glycine; alternate" evidence="9">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8303789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="123" mass="14322" checksum="861D0A602188E8B0" modified="2020-04-22" version="1">MRSKFKDEHPFEKRKAEAERIRQKYSDRIPVICEKVEKSDIATIDKKKYLVPSDLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTAALMSSIYEEHKDEDGFLYISYSGENTFGEALEEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKS7</accession>
    <name>A0A5N6KKS7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKS7"/>
    <dbReference type="OrthoDB" id="2283785at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039634">
        <property type="entry name" value="Bul1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904:SF1">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="414" mass="45309" checksum="C6FB10C367AEC1E7" modified="2020-04-22" version="1">MPIPETAYPQPRIAAAGKTYIFPFNFVIPEQLLPTACTHPSDADHVHTAHVQLPSSMGDRELSILDDLAPEMSKIQYSINAKVVKYTEFPKKSTSLVGGSKKLQIIPMVAEAPPMSISEDDKGDYLLSKTKSLRKGMFSGKLGKITVLADQTAAIVLPPPGSSSVATTMATVKLQFEPRDINSQPPRLGGLVTKIKALSFYATKPSKSLSSRSSIAKTFEPARQVYQASIPLSSRCVEQVSWVKHLPHPDLSRRASTISSSSSEYSDNSQMSLKTPDRLYYTAEILVPVSLPSSKIWIPTFHSCIVSRIYSLDLTLSIHTPGAGVPASSVKICLPLQIAARGNRTAPVSLTAEEAAAELADANEYLRPRVIEIPREDLVENSFLRSSFTVPRPELPPSYEHTEEPRRQVDPSRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKW2</accession>
    <name>A0A5N6KKW2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003833</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKW2"/>
    <dbReference type="OrthoDB" id="2587563at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8304436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="84" mass="8975" checksum="637A49F5B017056D" modified="2020-04-22" version="1">MGSSKNEETSVINNFSSISKPSNYIIYSVSNYTAPIKPQTMTAVVTATLSISPANTLRTTTGVMNSTAFSLFFSTRSHMGITTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKW6</accession>
    <name>A0A5N6KKW6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_003837</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Also a component of the nuclear pore complex.</text>
    </comment>
    <comment type="function">
        <text evidence="11">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
            <location evidence="1 11">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the dynein light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKW6"/>
    <dbReference type="OrthoDB" id="10033309at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030473">
        <property type="term" value="P:nuclear migration along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043935">
        <property type="term" value="P:sexual sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd21452">
        <property type="entry name" value="DLC-like_DYNLL1_DYNLL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.740.10:FF:000001">
        <property type="entry name" value="Dynein light chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019763">
        <property type="entry name" value="Dynein_light_1/2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF35">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01239">
        <property type="entry name" value="DYNEIN_LIGHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 11" id="KW-0243">Dynein</keyword>
    <keyword evidence="5 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8304440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="97" mass="11063" checksum="6CAF67C93A59845D" modified="2020-04-22" version="1">MAAPPQQVEEALVAQIKSVDMSDDMSDEAIEVCRQAMAKHSVEKDIAQYVKKAFDEKRGPTWHCIVGRNFGSFVTHETKHFIYFYLGHCAILLFKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKW8</accession>
    <name>A0A5N6KKW8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKW8"/>
    <dbReference type="OrthoDB" id="3436397at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="164" mass="18078" checksum="4DDA728366E5F9E5" modified="2020-04-22" version="1">MNYLLESQRQSSAILRATWLLVNLSEMSSQPSTIDNLKSTASSAYETVANSVSATSQNGKYDPDQDKNLVGKDSHGNKFRKGDYKDKLNQAAFGGPPEKEESLTEKGISTLQKSTLEQGPEDRIVKDNGLPPTRPEHDVPIEQFLRKQYHSRSGDGIPNPGESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KL21</accession>
    <name>A0A5N6KL21_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KL21"/>
    <dbReference type="OrthoDB" id="3364132at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="10"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="324" mass="35737" checksum="8678566B870E461F" modified="2020-04-22" version="1">MVVFSKLPHLGVSVQVDGVNVQEYDDDEEITVKPGPVGEYQAARTVSKFIEAVDGAEFGVKCSLSPQFKRDSPNIEVAVYVDGNYASGLVIRDTDFSALLEGRVIRTSDSSRNGDVMQKFRFSRLDISSEETRLSSLKQEKNEAEKIGAIEVRIWRASKSTPAYLTTSHQYSAASNKFHEKAFKGQAETHNVSYSTKTPIPAQNFVKTTKLDGKDYPIAIYKFKYRSKGTTKPTNFGVVANIDTDALKQLLIIERTPEPEYSPSPSPESDVDLGNLTDAQRERLKAFLRNEGIAAGGASNTPREKSSFKTTEIVDLTADSDEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KL37</accession>
    <name>A0A5N6KL37_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003894</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KL37"/>
    <dbReference type="OrthoDB" id="5387214at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="217" mass="23591" checksum="296EF5E866D677CD" modified="2020-04-22" version="1">MSSPVDEKSTLVNSNVLTINRPSPSRTQSNQSVLSTIEDVDSTHSLSPSQTRHEKSSLAQETSPFSPFYNPNPTRYSLEAQKSSSKQNIAVYDTDVEAYLTPQQTTKSGLLTKAKTGATQECTVWPGQQQMKRKKKAMKHDRISAGICGCMAGFDRKTRIWIKVLIALVVVALAVGVGVGISRAVGGVGRIDVCIGIRVVIKVSIGLQHILDQYICD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KL81</accession>
    <name>A0A5N6KL81_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Catalase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KL81"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.30">
        <property type="entry name" value="Catalase hpii, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF26">
        <property type="entry name" value="CATALASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="1">
        <location>
            <begin position="22"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="325" mass="36341" checksum="F3FB7B9D89908B6A" modified="2020-04-22" version="1">MAIKRSIILFVYLGSPETSVYTLTEGVPVADPTTSLRLNTFGLGGLMLFQDTQLIETLAHFARERIPERLDFGGLLESAEAEKLAGSNPDHHKLDLFNAIECGEFPSWTASVQVLELKDAESFRWNIFDMTKIWPHTDVPSRPFGKMTLNKNPTNFFADIEQAAFSPSNMVPGIAPSADPVLQARLSSYPDAARYRLGTNYQQLKSNEPHCSVYAPYQRDGLSSINGNYGSDPNYVRSSFGPLAPVTCKVQTVHDIQHELWSGKLTVFTSEVVDDDFENLVRNVAGDLANVKGERVRREAIEIFRRVDEDLAIRIERKIAELSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KL88</accession>
    <name>A0A5N6KL88_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005308</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KL88"/>
    <dbReference type="OrthoDB" id="5364416at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13563">
        <property type="entry name" value="2_5_RNA_ligase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="LigT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="163" mass="18836" checksum="9CE3145C20D92427" modified="2020-04-22" version="1">MTQPLILTLRLDGASEKLLTSLRTRYFPSSRNFLSAHITLFHALPPSNRPLYTSLLTTVTHRENRFTLGLKDPFPLGKKGVALNVSSFKLRKIHEELLAELRGKDVQLTEQDQRRLRPHVTVQNKVGEEEARRTLEEYGDEKHLIRLYSDFLKTASHLTQFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMT1</accession>
    <name>A0A5N6KMT1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Anaphase-promoting complex subunit 4 WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_004251</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMT1"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039328">
        <property type="entry name" value="WDR89"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="147"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8304931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="35863" checksum="55D03DCE984FE303" modified="2020-04-22" version="1">MYRFFASDTFEVKGAEPTYIYDIISVAAGLASISSDDCLRLLDPTALNGQPLNTIKKVNSDVTCLKTIGNGDSSIVVTAGRDGKVCLVDPRTCGKVGEVKSDQGAPILSLACSNTNGIAAGTELTNHQAAVSIWDARSLAAPIVQYVESHSDDVTELQFHPAQQSLLLSGSTDGLVNIYNITIADEEEALHQTINHGHSIHHANFLSDTDIFALSHDEKFSMYELVTNPEEGVEEPAPVVYGDMRESLGGEYVANVLCRPDGGAVLGIGSHSKNDFDLVQLKKGKPWVFSPETKVTLSGAHGSEIVRSFCFLDAHRAVLTAGEDGQIKSWRGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMT9</accession>
    <name>A0A5N6KMT9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMT9"/>
    <dbReference type="OrthoDB" id="309640at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00448">
        <property type="entry name" value="YjgF_YER057c_UK114_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.40:FF:000001">
        <property type="entry name" value="L-PSP family endoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803:SF58">
        <property type="entry name" value="PROTEIN HMF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="127" mass="13864" checksum="17E6CB4BE9D79AF1" modified="2020-04-22" version="1">MSDLTTVYTKDAAFPAGPYSQAIKTPSTIYCSGQIPCTPEGEILTLETSSISAMTELCIKNLSAVLKEAGSSIEKVVKVNVFLTTMDNFAEMNGVYEKLFKHKPARSESIYLFHKDGLRSGWASDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMU3</accession>
    <name>A0A5N6KMU3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">2-oxoglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="5">1.2.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">2-oxoglutarate dehydrogenase complex component E1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">EYC80_004259</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 2-oxoglutarate + H(+) = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:12188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:20092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="1.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="5"/>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMU3"/>
    <dbReference type="OrthoDB" id="413077at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1150:FF:000002">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11610:FF:000009">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12470:FF:000003">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000002">
        <property type="entry name" value="2-oxoglutarate dehydrogenase, E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006914">
        <property type="entry name" value="PRK09404.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008907">
        <property type="entry name" value="PRK12270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="18">
        <location>
            <begin position="562"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00042984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00051911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAB8304941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="973" mass="110178" checksum="72237985E9283975" modified="2020-04-22" version="1">MPMSQAFTPPPTLVPTPTGGVPSFLPGLGGEGSEVTNHLKVQLLCRAYQARGHHKADIDPLGIRREAEEFGYSKPKELQLEHYQFTEKDLDTEYSLGPGILPHFKKAGREKMTLREIIAACERIYCGSYGVEYIHIPDREQCDWLRARIEVDKPFKYSIDEKRRILDRLIWSSSFESFLATKYPNDKRFGLEGCETLVPGMKALIDRSVDFGVKDIVIGMPHRGRLNVLSNVVRKPNESIFSEFGGSAAAEDEGSGDVKYHLGMNFERPTPSGKRVQLSLVANPSHLEAEDPVVLGKTRAIQHYNNDEKDHKTAMSVLLHGDAAFAAQGIVYECLGFHSLPAYSTGGTIHLVVNNQIGFTTDPRFARSTAYCTDIAKSIDAPVFHVNADDVEAVNYVCQLAADWRAEFQRDVVIDLVCYRKHGHNETDQPSFTQPLMYKRIQKHTSQIDIYIDQLLKDGSFTKEDIDEHRKWVWGMLEESFAKSKDYQPTSKEWTTSAWNGFKSPKELATEVLPHNPTGVPAHTLEHIAETIGSYPEGFNVHRNLKRILTNRIKTVSEGQNIDWSTAEALAFGTLVGEGHHVRVSGQDVERGTFSQRHAVFHDQETEKTYTPLQHISKDQGKFVVSNSSLSEFGCLGFEYGYSLSSPDALVMWEAQFGDFANNAQCIIDQFVASGEVKWMQRSGLVMSLPHGYDGQGPEHSSGRMERYLQLCNEDPRIFPSPEKLERQHQDCNMQIAYMTSPSNLFHILRRQMNRQFRKPLIIFFSKSLLRHPIARSPIEEFTGESQFRWIIPDAEHGKSINEPENIERVILCTGQVYAALSKYRADNNIKDTAFTRIEQLNPFPWQQLKENLDMYPNAKTIVWAQEEPLNAGAWSFTQPRIETLLNNTEHHNRKHVMYAGRDPSASVATGLKSSHTKEEAKLLETAFTFGGHWVGCIRCKMYYCTEVMVLALVTLFDLHAFQIHFCSCGNLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMV2</accession>
    <name>A0A5N6KMV2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ZW10 C-terminal helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMV2"/>
    <dbReference type="OrthoDB" id="534815at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046362">
        <property type="entry name" value="Zw10/DSL1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055148">
        <property type="entry name" value="ZW10_C_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205">
        <property type="entry name" value="CENTROMERE/KINETOCHORE PROTEIN ZW10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205:SF0">
        <property type="entry name" value="CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22766">
        <property type="entry name" value="ZW10_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZW10 C-terminal helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8305170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="268" mass="30328" checksum="07C895B2B48B3186" modified="2020-04-22" version="1">MQPDHQSIPVSPAAGGLSNIPTLILAMFRAVSPCYYADNPKGNMFSYNDAMWLVDRLKTFSTEWHSRKDLTPRALNLVKVDSEIGPLESFGKRAYKNEMDTQRTILHDLLGGMLSENAIQSVISHINQQSASWKEILPYSTWASAVGTLVNTVATKIINDVFELTDLGVDEAERIASLIQQVNRLDSLFKTNEIGTYADKWLKMQFLSEVLQSNLKDIRFLWFESHLSLYFSKDEVRDLIELSFENNPNSRSLIKDIKEKPLPDVGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KN54</accession>
    <name>A0A5N6KN54_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_004430</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KN54"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000001">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="83"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8305135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="337" mass="36619" checksum="47B32FC9301CFB95" modified="2020-04-22" version="1">MHGPLIPTFHSGARTCHPALSSLLGDTTVPKVIFQKVNLQLTTKMLTLQRLVVSALLILTITFLFFAQTAEAAKGPKITHKVYFDISHGDKPLGRVVLGLYGKTVPKTAENFRALATGEKGFGYQDSTFHRVIKGFMIQGGDFTKGDGTGGKSIYGAKFPDENFKLKHSKKGLLSMANAGKDTNGSQFFITTSTPAHLDGRHVVFGEVLEGYEIVEKIEDVKKGGSDRPVEAVKITESGELPVPEEDVYGTAEFQPGMEEVEVPLIPADPSKPAAPTADIPVVGTAKTETETEEFGYADEASYTLLQKGLFLAVILGCVAFYVRMNRRSKKYEKSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JLS5</accession>
    <name>A0A5N6JLS5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Stress-response A/B barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_010188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000025">
        <property type="protein sequence ID" value="KAB8288183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JLS5"/>
    <dbReference type="OrthoDB" id="1601230at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013097">
        <property type="entry name" value="Dabb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044662">
        <property type="entry name" value="HS1/DABB1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178:SF10">
        <property type="entry name" value="STRESS-RESPONSE A_B BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07876">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00886">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stress-response A/B barrel" evidence="2">
        <location>
            <begin position="3"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8288183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="110" mass="12431" checksum="E681820BF0FEF6FE" modified="2020-04-22" version="1">MTLVHIVLFEFKPTTHKDEIDDLCKQMLSLSTLCLHPESKKPYIQASSGGRDNSPEGQQGGFSHAFVSHFANSADRDYYVKEDPAHLEFVEKAGRILQNVRVVDYDMGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JRY1</accession>
    <name>A0A5N6JRY1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_011130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000018">
        <property type="protein sequence ID" value="KAB8290264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JRY1"/>
    <dbReference type="OrthoDB" id="629492at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8290264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="484" mass="54617" checksum="56F7A37669E47DED" modified="2020-04-22" version="1">MPPAYDEEEGMGPLEKGRHRYQKKNYQGALLAFTEAIKLSTDNLLLTALDHRAATFEKLDLLQSALRDAKEMLELKPELSKGYLRCGKVLQLKGEHKLALKIYERGLGKVKVGTDKDRVGLFECQKKLSQKALRAYLKRSNYTVGEARIRNGSIDSAKFQYLIRTCTKLQRLEVFGGDPVGESLTSALPLAKSLQYLKISWECVISFPSALESLRHVQATIVEATFGDIHYYVPSNSWTWPKLENLQTLRIDSRHRDGILLKNLIDSIPKIKTLSLKRFDLEGVVPLDLRELQGLEDLELIDCGLRRLPLLPSTLKRLVLRDNLRLFDQQEDTVSLSLLETFNCDSTGLSDETVVSVIKNAPNLKHLHMGSRLVGDYIATHQSFPLCENIEELCVSYLPYEEKDFINLTSKCPNLKRLDISGTKITGVAVKHFVGQGITWIDLQVCDKVSPDAVEYARGKGAEVIFSFGRRSRPSWREQVGGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JRZ1</accession>
    <name>A0A5N6JRZ1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JRZ1"/>
    <dbReference type="OrthoDB" id="674948at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40129">
        <property type="entry name" value="KETOPANTOATE REDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40129:SF2">
        <property type="entry name" value="KETOPANTOATE REDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8291061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="312" mass="35135" checksum="BA51825A772BD9CD" modified="2020-04-22" version="1">MCNFHNVITLLTSQSEVREINDNFLQHDHYHLHETSKMSNDSTSTAEILILGAGWTSTFLIPLLQQKGIKYASTTTSGRDGTYKFRFDPEGGDENLKQIHGLPTAKNILVTFPLKGKGQSRLLIEQYSDTHSIDSLKDSRNTSSFQFIQLGSTGIFTIPGQSTWVTRHSSYDVSNDRAMAEDELLQLGGCVLNLSGLWGGERNPKHWIERVAGTKEMLSGKKSLHMIHGLDVSRGVVGVIGNWEKARGQRFMLTDLMVYDWWSLILGYAGELDEENGNEKMEGRQDLENIITRAGHNKKLPRRIDKEPITQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JSA2</accession>
    <name>A0A5N6JSA2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_010085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JSA2"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8291409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="83" mass="9482" checksum="3965BBCB1CB1482F" modified="2020-04-22" version="1">MKIKRVKGQRFKTPDINRACSCHRNKLIAIGANHTSFLNFPPLNCAYLPREFQAAVDRQNVFCAVDCLIPMYVQVLIPGHRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWB2</accession>
    <name>A0A5N6JWB2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Matrin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_007569</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWB2"/>
    <dbReference type="OrthoDB" id="24683at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000299">
        <property type="entry name" value="Zinc finger protein 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051879">
        <property type="entry name" value="C2H2-ZF_Maturation_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="11">
        <location>
            <begin position="50"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8293232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="126" mass="14187" checksum="6776D71ECFD039F7" modified="2020-04-22" version="1">MGIPQKSTKTKTRRRLRDLDQISADLRSPKHLAQHKSSKAAEDLPGLGKWYCIQCAKWYESENSMVSHLRGKPHKRRVKALKEGPYTQRDAEAAIGQGPADNGARNKALNVEVEMENSAFLDDQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWB6</accession>
    <name>A0A5N6JWB6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWB6"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="188" mass="21727" checksum="4196D3850723F80D" modified="2020-04-22" version="1">MDDLFWFGLVYVYVYVYVYVYVYVSHTFLCINQLSSAQLISSRFGSVQFGSVGREGGQESRKKISFFFSLVDDGWMDGWMDMLGRIVESWNRELIFMYVYTKKKDRFRAASFLGLELELELSLELELVFVFDMRGVGACMGEVREAREVRRLFAGLGWAYSVCVCVCVCDFLEGTWGLGLGWVVKVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWC2</accession>
    <name>A0A5N6JWC2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenosine 5'-monophosphoramidase HNT1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Histidine triad nucleotide-binding protein HNT1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_007573</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine 5'-phosphoramidate + H2O = NH4(+) + AMP</text>
            <dbReference type="Rhea" id="RHEA:67916"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57890"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:67917"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HINT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWC2"/>
    <dbReference type="OrthoDB" id="672793at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01277">
        <property type="entry name" value="HINT_subgroup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.428.10:FF:000013">
        <property type="entry name" value="Hit family protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039384">
        <property type="entry name" value="HINT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648:SF1">
        <property type="entry name" value="ADENOSINE 5'-MONOPHOSPHORAMIDASE HNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648">
        <property type="entry name" value="HIT FAMILY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="12">
        <location>
            <begin position="8"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="10 11">
        <location>
            <begin position="96"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="9">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00052319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00074222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00076050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8293239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="165" mass="18677" checksum="620AA3C7894FCD13" modified="2020-04-22" version="1">MASQAACIFCKIIKGDIPSFKLYESEKILAFLDINPLSRGHALVIPKFHGEKLVDIPDDQLQEILPVVKKLVVASGAENYNVLQNNGRIAHQEVDHVHFHMIPKPSTEEGLGIGWPQQKTDMEKLKALFAEIKAKMQHKINTRIAVTSKKSQRIRGRYYHQMPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWC9</accession>
    <name>A0A5N6JWC9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA ligase ATP-dependent C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_007576</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWC9"/>
    <dbReference type="OrthoDB" id="206088at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050191">
        <property type="entry name" value="ATP-dep_DNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674">
        <property type="entry name" value="DNA LIGASE 1/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674:SF9">
        <property type="entry name" value="DNA LIGASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA ligase ATP-dependent C-terminal" evidence="4">
        <location>
            <begin position="44"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8293244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="138" mass="15800" checksum="D7A1A262D4086AE3" modified="2020-04-22" version="1">MVRDARQNSGHQFSSHDTFYKANKEFYSESGEHVLGSKPNYVDYRGGNPDVWFEPQEVWEMAYADVTISPVYRAAIGLVSDEKGLSLRFPRFVKKREDKSIEEASTGEFLAGLFRKQEKRVDDGKGELEAVDPEEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWF8</accession>
    <name>A0A5N6JWF8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histone H1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_007612</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Could act as an H1-type linker histone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the histone H1/H5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWF8"/>
    <dbReference type="OrthoDB" id="1110759at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000383">
        <property type="entry name" value="Histone H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="8">
        <location>
            <begin position="33"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="97"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00055135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8293282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="248" mass="25192" checksum="0CFADA36B8F00BA2" modified="2020-04-22" version="1">MPPKAASTATAAAAATAPAAAAAAPKVKATPSDHASYQDMITDAIVNLKERNGSSRIQLKKYVKANNTINASDSMFDSLFNRALKAGVTKEVFIMPKGSSGTVKLAPKAKKTPAEKAPKKPAAEKKTGEKKAAKKAAPKKAAATKEKKPTDAAAKPKAAPKEKKVAAKPKAAAVPKEKKAAAAKPKKAAAPKSATPAVAEKPAVLKKTASGRVTKAKTETKKAAAPKKAAAPKKAATKKAAAPKPVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWG7</accession>
    <name>A0A5N6JWG7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1577640at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1452"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1471"/>
            <end position="1485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1486"/>
            <end position="1523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1570" mass="175388" checksum="7D8A51B1CC0277EC" modified="2020-04-22" version="1">MSLYAGTKFIGPEELAIIGLMEAIFQLADSGTIFINRLNKLRSRTSIPGVFSGLNALVPVKEKVSWLVGIIKKHVEKETIKHANAESRQSVSSIIKICTFQLNYLSNRIFVATGSPISQKTALISLFGKKKDILERVNFIDIQAKDLTRLLDYLNNVRPTPRPGPSISNPPTSLVPRVPCNDFVGRDKMLEVLQRKMNTTGQVALDGPPGIGKSEICLQYARKLQDKALMKWIFWIDGKDPTGSFATIARYLGLDLSNQESPASLVLQWITKSNDESLIIVDDVDDVDSTEHSYYTSERLIEALNESPGEASKRNDSMPKVKSLPSLPFRSTRSLGKIEAANQNRRGNLLISSKALIAQNKTMEKKNLAVERVPSLNTLEATKLLKELIPKSLLSSERHCNDIIRLVGSLPGPLKHAAKYIEDTGITTAQYLSAYEKHQIIEEKSYHTPTSSDDEVQIAAMRISKTFSTNEMFKSLLEILYSANVGNDRIIKSIETQLLEYSSDLERIWFKRAVQGDELENKLPAFIREHHKRLSCLLVLRDPVEQTDCFSFAPRRLSPINSPKTGVSRRSSFSLRGISDRMSRQNSITEEQKQMLASRIILTKTVRDETMDESKELEQFYFDEKAFSRFLINILHHLNTLNQLERHSPLFYQAEHILKLAPLATTVWISSYKTTTVTYNVEWELPQVLDRDFSLDQPLSTVVAISGKADLAEAITCGEFISKFWKHGVHLLDALSGPKCQWGRNEMTSANDGIKLQILETKSQHGAEIDDGIEVNTHKTKSPVNRSHTLKVIVEGSEEVQSHIAQTIAWLAAAVRYSNFTKLHESRASMDFYILNGALNCTIKSLPLTPLVEFCIDSSCWHSLFTNTVLAIDYPPSKPRGSGQGLSIPVELLMSLARTTIITELYKGFVIQGYQYALVPVGNITTERDEAACSNSIIQWHLIDTRSLDVSSASLPNRADRGIRSVAKSIDILNSFIEPGSHAFLGWCSKVNIHVGTDTTNVQNGAVHLEIQATNRPSNYALRYRDPRLRFLQSSARDAGRAIAITTINANAAGGGHGATGGMGASLTVGESREAAVVGRYGSLREALQSRSRENIVLYDTATRRAWMLPFLNVVLYLVHLRELATTPHDATSTITMPWAVRQHAGRSDGPAWDAIRPYLDLLDTENFNKNRLNRLNNHFTGRELRLKLALRLADHLEYLITMIDATSKQNVAWRSKEMSVFHHSKIYGFEMEELSYAASLGYKEQKLHNTSGGWAKMRRNREQVLFCSGIGDLITPLLTPESDDRLCLSSTWHGLPGSSGHFSNPCPHYETDESDGHQKTIRLSKSPQPSNLEDFSTYMDGAVIFGRRARYGPLRSCGAAIKKWMTGFTSRRTRNTQPSVLIDAHSPVERPTIDEPFAEIPLENELSAPGLIVLPFEDSEADTSTSEESYPQTSTSDSDIFAQDLFQEQEPVPPSIPAVPAQPGSEHMASNPNRLRPNNLTLSTVSESSYEPTQATTLSPSMANNNDGSRGTTPETSSPVDTFNDSSEIKMFFQLIIPRYFQIELSHDFLYVQQESVAIEAVFFIYLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWI9</accession>
    <name>A0A5N6JWI9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_007635</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWI9"/>
    <dbReference type="OrthoDB" id="10020333at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14019">
        <property type="entry name" value="STKc_Cdc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000478">
        <property type="entry name" value="Cell cycle protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF23">
        <property type="entry name" value="CDC7 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="84"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="457"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8293306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="481" mass="55281" checksum="EAB4D755EAFB4F5C" modified="2020-04-22" version="1">MSTTRQRQGNSKNSFQIHNDEVKQEESMEEESNEIAESRAEDDDAVQDEAYSEDSDESDDAVDPATAEDIAKFEATFKGIKDRFRLINRIGEGEQNTLDLLYEHYDNDWDLEEKEQSAWTSPPVKKRKTGGVREVMNEYNQQRRGKKYVAIKKIYVTSSPTRILNELDLLNDLRGCDSVCPLITAFRHTDQVVAVLPYFRHTDFREYFRKMKVSDMQVYFRSLFTALKAVHAQGILHRDIKPTNFLYEPEKQRGVLVDFGLAEREEEDTKSCLCTKDHDVRKRKLENSVAIQNLPSAGYPKHDNRPSRRANRAGTRGFRAPEVLFKCQEQTTKIDIWSAGVILLTILSKRFPFFNSADDDVEAMIEIATIFGVKRMKNCAYLHGTVFETNIPTIGQAGFALEKIILWSTCRNEAGPDGAEQPLTKEEKLAVEFLERCLELNPHKRISAEDALNHPFLLEQTEDEDIKNEDYEEDELSMIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYF4</accession>
    <name>A0A5N6JYF4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYF4"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8294176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="187" mass="21795" checksum="658260432EADB061" modified="2020-04-22" version="1">MSSCLNRRQGRQDRQVQFKEKDIVSIFGSPQQKKKTPKKIKPKRTYPNTLHQSHNSANQKEEKKKKRESERARERARKKERKKGRKETDRTTTRTYYIRSPLLRLLVPHQKREDFNSSSSSSSSSSSPSASSYSYYHFTHSLTHSLTHYLSLTSLPILSTYYYCTGTRIISARITRTDLDNTSIGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYF8</accession>
    <name>A0A5N6JYF8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYF8"/>
    <dbReference type="OrthoDB" id="3564184at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8294194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="124" mass="12248" checksum="787B166E6FE1A01D" modified="2020-04-22" version="1">MPGVPPKAFEAIKAKFKALLKGKKSKKAEADPAADATKTDAAPAPATATSEAAPATEATAPEGDAAEPSTATETPAAPTTADHAPAVVEPANTTEPAAPEASKDEEPVKTEPSAPIVAATAPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYG2</accession>
    <name>A0A5N6JYG2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_009636</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the REI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYG2"/>
    <dbReference type="OrthoDB" id="19329at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040025">
        <property type="entry name" value="Znf622/Rei1/Reh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182:SF8">
        <property type="entry name" value="CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182">
        <property type="entry name" value="ZINC FINGER PROTEIN 622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="142"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="298"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="150"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="332"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8294202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="434" mass="48133" checksum="8814296B45850B27" modified="2020-04-22" version="1">MSSITPSRSAASGASGQADINASHPYTCNTCQVAFRNSDLQRGHMRSDWHRYNLKRRVTSLPPISSEIFTEKVLQAQASSTAAASKAAYEKACTICTKTYFSENAYQNHLSSQKHKARVAMVGDGHADDASSVMSSTFSLGEPIKTNGAADEDTDAQVEEVSEGIKKTNLEDAEASAATPNEDDAMEDDEDALVEVSTSRCLFCNEDSADTSANATHMERIHGMYIPEKEYLVDLEGLIAFLHEKIYEDHECLGCGKLKQSIFGLQTHMRDKRHCRIRYATEDEQIEIGEYYDFRSTYSDEEDESDSEDALPGKQKSGGVKLGAKRPTTIDAEGDEDMENGDGWETDSSESSLDSADLTAVPLDERTHQTGGTHMLISITMLPSTLITNFTYLLVVPRDIDHYKNITVKIWSIIHHQRRGNDVQLRLLRIPILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYG4</accession>
    <name>A0A5N6JYG4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_009624</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYG4"/>
    <dbReference type="OrthoDB" id="2015534at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="295"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="128"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="467"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="531"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="191"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="467"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="576"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="603"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8294186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="631" mass="68295" checksum="1BC5E2BB4A6DBFF8" modified="2020-04-22" version="1">MSNQKLDTLFRDLEQVDGDPLFEDVEGNEKALLDSNRTIGLGLAMVARVVRNMDGQLRLKSEVGKGSRFVIQLPFVLPYDDSGNSGNQEKAAFLKTPSISPSIASPPPAGTPGEVTLVEKSSFIRPNAEPSISRKRSREEIASLHSFKSTTSSKVSGRSDMDRLIDAISGPIGSAPGEPLQRADSKDRHSLNSMPMNSTNSERPADLKRSSSYTSPDYLRLEYSRAARADIITDTRTPVKAVRIPDEFLGNMNDTIPPSVAAKVKFNTQSSSSSQSGNEDEPIPNSKTHNTEHLKVLVAEDDPVNSRIINKRLEKGGHEVFHTINGEECASAYGDNVTNSSTTTNTSSSPTTQFDVVLMDMQMPIVDGLTSTKMIRSFEKTHLNLSPRAKLNGRVPIFAVSASLVERERQTYIDAGFDGWVLKPIDFKRLNVLLEGIVDSKVRESCLYRPGEWEHGGWFHKMQPSAFQSSTAPSNETPVQNPPQIGPEAPQPDKDSLDSDTGSSTPRDDKKRPLIYDERLNAANEALNATAAVDVGPNNDLPTADERPVIDVSNEEVTPTPKQSIPDGADKGIEDTTATAKVNDSTDSGPTADSYFGADVSNVVDQSANSTTADGLSAESTNDAETTDSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYK8</accession>
    <name>A0A5N6JYK8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_009675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYK8"/>
    <dbReference type="OrthoDB" id="161814at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF73">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN CTR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0187">Copper transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8294244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="218" mass="24773" checksum="C4E5876054B5CAAF" modified="2020-04-22" version="1">MSAQQSAQSLLNALLKSSISQLQESNMDTNMDTVMASSNLSSSTAAPSMSNSSCKMFMLLNWHTLDTCYLTSTLHIRTPLHFTLICLFSFLLPIILEITRRYQRIYDRYLRAKQIHYLQNAHESSPLDEISEKLLGGPNFKRTNWDSSVVLEQGLRAGLHLVQFALSYCVMMMWMYGNGYLLICILLGAMTGFGMFTRDMLAVFVQESDTDEREQTCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYK9</accession>
    <name>A0A5N6JYK9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYK9"/>
    <dbReference type="OrthoDB" id="346839at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8294253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="167" mass="19473" checksum="DD0A72901AC38616" modified="2020-04-22" version="1">MIPLEPAYQSHSMDVLNRNLAHFGADYLSEWRFEIGREHPWNSMAIRSKHSPLPCLMLSVKFRRGTCLPFRLNSASFPTPFKTIKEQTNTFDIIHQHIETSTLHLYSIIKFSINKVFKRANFFSTASSSNLDHRKYLCQYNNTFRRVFSQSLIPHRTHHSASKSTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYL2</accession>
    <name>A0A5N6JYL2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYL2"/>
    <dbReference type="OrthoDB" id="346839at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8294252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="129" mass="14931" checksum="4F2F9DEDB4ABDF46" modified="2020-04-22" version="1">MESNDSPAHSQTTVLGLYLIYVKFRRGTCLPFRLNSASFPTPFKTIKEQTNTFDIIHQHIETSTLHLYSIIKFSINKVFKRANFFSTASSSNLDHRKYLCQYNNTFRRVFSQSLIPHRTHHSASKSTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYL8</accession>
    <name>A0A5N6JYL8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LAGLIDADG endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYL8"/>
    <dbReference type="OrthoDB" id="2043at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024986294" description="LAGLIDADG endonuclease" evidence="1">
        <location>
            <begin position="20"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8294110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11558" checksum="D22D2AD7AE0FDF64" modified="2020-04-22" version="1">MAFWTWGRCTLCCISGVSYELLRGGDYTMKLLLGGIHCSFTAKAIERVFCGIGSMSFENEQNMCKTRFSGQYLYLEYRIIIQSRDVPSIDPYTFLITPDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYM6</accession>
    <name>A0A5N6JYM6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_009598</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYM6"/>
    <dbReference type="OrthoDB" id="7295497at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF19">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="274"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="221"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8294155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="316" mass="35887" checksum="95F493F23F335C16" modified="2020-04-22" version="1">MRQEQKVKDAWAIQEQYERANSEQVTPKTISPKDVDLVYHEEDDANIQSFPPLPMSYRSQSIIPHEPSESEDMSLSQQSYGSMATTRRESSSAYSTSSQSTSRQSQMAFNTSQTPTVPQHYPFVPSTQRQTSNMSNVSNMSDMSHDFPATMTSMESGNSEYSPGQEIQRPSKTSANSGTYTCTYHGCTLRFDTPTKLQQHKKEGHRNSTSLINNMGGESRGGMTSMAQKLNSQSGPHQCTQMNPSTNKPCNIVFSRPYDLTRHEHTIHSMKDKLRCEYCTEDKTFSRNDALNRHMRVIHPDIKVPEKERKKKKDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYM8</accession>
    <name>A0A5N6JYM8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_009696</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYM8"/>
    <dbReference type="OrthoDB" id="5054775at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031930">
        <property type="term" value="P:mitochondria-nucleus signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021711">
        <property type="entry name" value="DUF3295"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053043">
        <property type="entry name" value="Ras-cAMP_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28014">
        <property type="entry name" value="NEGATIVE REGULATOR OF RAS-CAMP PATHWAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28014:SF1">
        <property type="entry name" value="NEGATIVE REGULATOR OF RAS-CAMP PATHWAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11702">
        <property type="entry name" value="DUF3295"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitrogen regulatory protein areA GATA-like" evidence="2">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3295" evidence="3">
        <location>
            <begin position="89"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3295" evidence="3">
        <location>
            <begin position="274"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8294269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="640" mass="70903" checksum="50693453F1B3E9CF" modified="2020-04-22" version="1">MPSRLNAPVLTVDAGLIHKVDTRNVENLYSMWTVFSRCAGSLEEGRRLENLSWRLWNRETFCCEPTSEANATTPAISISSRSSEGQYSNDLPELSGSLDSLVDEEAIEFEESSDASPLDISHPQIQRQDSCNSRSRGRERHITPDDLEKMVITIKEKKDLAPLTITTPYLAPLAERIPEFIQPKYQSSAPAMVANDSLSTNSSAHSVAPEFVTGTPEKSATSVVKGFLSLPCAYIAAADTSKALAPKKKQMFALGGSSGEDSLSEQAVSIDNTPLTLPKKKPAKFSFGGSSNEDESSLPNRMQPRSALTDKLQKPLPKKQTSFQEEVATRTIQEEAFDDDVFETDDEDDVDESAIDDDDDDSSDWEDSNEESGNASIDDKTFFQRVDSRPQLTSRRSLITTMLHQNDRAQALATEASRSTPALRRSRNSSPNGPSLAASPESDEAPLMMKGLKPIAEIPRGAQPIVKSATNSTAHHQALSPRTTRRNMLATELTVSLRQNLLWERKQKSSVNEAAAALKRRHTAHDVANLKQYPERVYMDKDDQALNSSWNQYFSQGLGEYHSKGCDIGRMGQKLAHKSYQGVYNFVSSGIGSYFGMGFVQYPIIWEERDWYGVNLRGIFGSIRFYATLQGLRVELSLCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K022</accession>
    <name>A0A5N6K022_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K022"/>
    <dbReference type="OrthoDB" id="3870679at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="248" mass="28337" checksum="B53AA0BF17472A87" modified="2020-04-22" version="1">MMTALHHQTEIGTIIPDTGLLKRKFSLSGRRKNNSTQTSKPEANPSTHYPSVLDQPADDSRLHPFWRPANFWDDLEDIENDSDEDEEDYFPEYHSPGNRRIIAKRSISRKLKRTFAILPVSYANDDYVLSPLDRKTIRRSPSGNALRVVKQRSNNTLRRETDQRVLREARPGEFGHGFKEGNGGRIHTIPGLGLRIEYVGLRGLGKKLSERRKEQRNAKLRATISAPKDVRNGVEILESRSADSWNVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K031</accession>
    <name>A0A5N6K031_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K031"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.330:FF:000074">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8295130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="36447" checksum="5FF2BBFBA4B2F7A0" modified="2020-04-22" version="1">MTENKDSVAQTLEEVYEIPLRPVKFPLILPAHAPHLSDQGWSTLTFAPTDPIHISSHRLLQASKSFFELPHTYKSQFHTGKGTEEGWNRVEGEKEFITLREINSTPPELLDAAKEFWEVTGNALNRILGEIAGSLGMRKDLLTRYSEPCSKLHEKRTATMIRLFRYEGDGVYGKVVSEPHRDLGLLSLSISDVPGLEVLNKHTRTSFPIERSYGGKDAGTVLVGRELEFLSNGRYHAGGHLVRMYPEVMMRNEPDEEENGNKQHLAAVKHYRYSIVFVLRGYEDLAIDTDELRTPITGQWKKPMRGLKMKDLYRAEKETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K060</accession>
    <name>A0A5N6K060_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_007037</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K060"/>
    <dbReference type="OrthoDB" id="333239at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="1"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="226"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="262"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8295099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="432" mass="48302" checksum="F52007092397DEB8" modified="2020-04-22" version="1">MDLTASLRDLYKQMSETQEGFPPLMFLNALRQAFPQFNEKAKNGHGHAQQDAEEAWTQILQVLRSKLKIKNEGGILGGSSSAEVSFVDKYMAGAFKSVTECDEQGAKDAGEQPVSGEDVFLKLDCHISGATNHLRDGIVAGLEEKIEKRSEVLGRDAIYTKKSKISRLPKYLTVHFVRFFWKREAQKKAKIMRKVTFPDELDIVEFCTDELKQMLIPVRDKVREVRKEEEDVERARKRQKRIHDKEEADKKAGLVDEAPSSSKKDEKKEAKPKDGDTAMEDVAYKTDAEIDAEKAAAILEAKKELHALINPDLAKDDGANKSGLYELRGIVTHQGSSADSGHYTSYVKKQGPLDPKTGVRGEEDGKWWWFNDDKVSEVEAEKIATLAGGGESHSALILLYKAIPLPTAEGISHEQFGMHYAVIANEIFGSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K068</accession>
    <name>A0A5N6K068_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_006989</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K068"/>
    <dbReference type="OrthoDB" id="18472at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000319">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF417">
        <property type="entry name" value="CELL CYCLE PROTEIN KINASE DBF2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="198"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8295047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="296" mass="34032" checksum="F5BDECB5132E5F30" modified="2020-04-22" version="1">MFCCVDALHQLGYIHRDLKPENFLIDSTGHVKLTDFGLAAGFLAPGKIESMRVKLEKVGETYVPFGKPIEERTVAERREGYRSLRNKDVNYAKSIVGSPDYMAPEVLKGDEYDYSVDYWSLGCMHFESLTGFPPFAGSTVDETWKNLKHWREVLKRPVWEDPNYFISNRTWNFITSCITSKIKRFSNISEVYGHQYFAEVDWNTLRSQRAPFVPELDSETDAGYFDDFSNEADMAKYKEVHDKQTALENMADREDAMSKSLFVGFTFRHRKPNTDDDGKVSPRKAIPTDGTFGTML</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K076</accession>
    <name>A0A5N6K076_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_007118</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K076"/>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050668">
        <property type="entry name" value="Cytochrome_b5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359:SF14">
        <property type="entry name" value="CYTOCHROME B5 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="7">
        <location>
            <begin position="207"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="59"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="174"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8295196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="289" mass="32180" checksum="9041272E02656409" modified="2020-04-22" version="1">MENEVHLYMVLMVWKTSYTYLIVADENERMKTTHPPVIQPIAASTIPLTPYLILLPRPNPTINPSHHDTKHPKSGENPLKCPLPSPSPTSAPQTSQPSSPHLPSTSTSLPSTNISKKPSCKTKKPESANAYNRNRNAGEQSITGTKDASAQQTRSSEDNRHRGEHIGDHSYNPNPNPNPNPNPTQPQPLRRDPDDQPLYRPTKSKMTKTFSPSEVATHKDAENGMYIIIDENVYDVTNFLEEHPGGSKILKRVAGKDASKQFWKYHGESVLKKYGEKLKIGLVGEKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K077</accession>
    <name>A0A5N6K077_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K077"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8295181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="119" mass="13239" checksum="8079BD8192896723" modified="2020-04-22" version="1">MTMLHNRITLVLSQPKFGSCWNGISLLLHMIILHAEQGVISIYGYVRGNKVLGRDRQLLISLENLGDNQGSITFRSKAACPGIISKAPDVCVEHLALRNHKLIDDHPSCRILRVSVVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K079</accession>
    <name>A0A5N6K079_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_007052</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K079"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="445"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="230"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="405"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8295119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="56698" checksum="2DB5F75EF85DC899" modified="2020-04-22" version="1">MKEERGARELVRAVSPTLEDEDITSMGYKATSIMDKQLRLRIIFWRFSTSSDKIFQIVAVLAVIGAGTTRPLMAMVFGSLVHDFNRSAIITLFSGFFTIPHFETPAEGRTSLIYSDAAALLEEVFSSIQTVMTMGAEPKLLERYNSYLEKLKTSKLKRSLISGVKLALSYFALLSAYALAFCGNVVIVILCVNMSTHALRQLLPSWTMLAKATSSARNSGKFPDEISGRIELREVRFAYPSKPSIETLSDVSIVLERGKTTAITGFSGSGKSTIIGPLERNYDVSSGEILLDGENVKDLNIGWLRNQIGLVQQEPILFNDSIFQNVANGLHNHRASTLTQLSYRINWQQFRKLMTCDEKAPMNTARTEISALPPIESGATSQQRTLIRCLGLIMRDLKHYRPLFIIGTLTCIISGGIYPSQSIVFANSVTVFEFHGGLLKHNGTFWALMWFILALGVCLDFGTMGTIFSAIAAIVGQHYRNSYFAAILAQDASFFATNDHSPGSLTAQLTSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K084</accession>
    <name>A0A5N6K084_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_007104</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K084"/>
    <dbReference type="OrthoDB" id="16547at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025052931" description="CFEM domain-containing protein" evidence="10">
        <location>
            <begin position="19"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="11">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8295178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="175" mass="16542" checksum="233F6E5C1BD43238" modified="2020-04-22" version="1">MQFTYTAIFTLFASVAYSQSIASEVAQLPSCALSCLATAATSAGCGLADYACQCGDAKDAITKSGTPCIVAGCSASDVLAVSKIATQICVLQDSAGSPSSSPSSTSSASSSAASNISSATGSYVASVTSSASSVASSLKSSATSAAVATASAAAGNRVAAAGAAVGAGFLAAFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K091</accession>
    <name>A0A5N6K091_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_007112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K091"/>
    <dbReference type="OrthoDB" id="413460at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029256">
        <property type="entry name" value="Heliccase-ass-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057931">
        <property type="entry name" value="RHH_ERCC6L2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25806">
        <property type="entry name" value="RHH_ERCC6L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14773">
        <property type="entry name" value="VIGSSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated putative binding" evidence="2">
        <location>
            <begin position="29"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="ERCC6L2-like ribbon-helix-helix" evidence="3">
        <location>
            <begin position="121"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8295190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="210" mass="23898" checksum="F4004ECAF02FAFF7" modified="2020-04-22" version="1">MASFDVQAALDDDDNPLRVDDDDPNSAMSQLAALITEREKDIKRKQKSTPKSDPIAAILASAGVEYTHENSEVVGSSKVEERLSRRAEETGGEIGYGEEVLFASHRQGGNGNENIQYVFHPPEDVMQRQFCTMAKTFGFASATEFAFVVEGWTQKQRTDFLERFYLKRRERLAELEREELEKETAKRLEKMRNDTHVDLEGETESDDNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K097</accession>
    <name>A0A5N6K097_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K097"/>
    <dbReference type="OrthoDB" id="1872003at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8295201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="11563" checksum="5072ED9BB6AA8287" modified="2020-04-22" version="1">MPNLENGPNTGADVLISAYGSESGWVRCGTDKVVSPCSIKQLGKRDMDSLATNIHGLMIPSSQWINIPAETDVATAKDMYRSLAHAANAILAVMDDLELIGVLHIGDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K099</accession>
    <name>A0A5N6K099_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_007135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K099"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="1">
        <location>
            <begin position="30"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="151"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8295215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="359" mass="40150" checksum="72E8C963D7B609A7" modified="2020-04-22" version="1">MSARSSTKSTSGIADEDLSNRKFPDILPEILRTILSERLKISESEIGPSARFTGISVDSLMALETPSMIRSRACKNIDPNFFCDYPSFGGVLKLESTQANGVERSESTLVLKETYYGPKKSPQAISVILQQSPTIYELISPFVKSPADFKGTMAWIASLYVGEICKKQKSGPYILGGWSIGGIYAYEAARQLIIQGEKVSRLILIDAPCPTKLPPMMLETIDRLEELGIFDGFAGSQYRLPSLVRQHFQSSILALKQYRLEVIPDGKRPHCLAISAKNGVLDSTGTNQEILHNKDGISDATSRWVMQARNELEDDGWEEMFSEFERRFVEANHFTMMQRPVNKAVAELISEFIGRYEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1U4</accession>
    <name>A0A5N6K1U4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ketoreductase (KR) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_008818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1U4"/>
    <dbReference type="OrthoDB" id="3558135at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8296004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="24953" checksum="2AEAFA9D76A989C1" modified="2020-04-22" version="1">MIKLGNVSCGVSIVENFANEIKTEIVAQKLDPLLAIICNAFTWSISSGLQFTVDGYLLVKPGPDREGEETGRGFQRYGISKVVAIMGMYQLNARLQKSPSPHLRKITALALDPGGLPDSRCMSSGSDVPAMWTFLMKGILNPLFLGLLRPVFKHTVPKLSLRSTSEAAVDLVEMAVGEGFRGERGHFVMGERDESSPETRDEGKQRAVWGKSLEWAGIGKGDTGLGEGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1U6</accession>
    <name>A0A5N6K1U6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008892</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1U6"/>
    <dbReference type="OrthoDB" id="10253115at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF30">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="73"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="529"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="614" mass="66196" checksum="81923BEF3113A57F" modified="2020-04-22" version="1">MAFRNCFAEVGILMGAGVGVRVRGRMGAGNRLLRLRGAMKGARIQGRGLLTESYSVGSAEPPLLPHTIPEHFHRIVEQHGSNLALVSHAQNAKLTYRELDERSNVLAHGLRALGVGKGDRVAVSLGNGWEFGALTYAIWKLGAVLVPLNPAFNTKQVESALNHLGTSHLVIGRETHLPFKNPRDNTPLLEDLIGDLAQANWRSETVPSLRNVVLVHSAEGDGSAGFASTTPFRDLIQGYESQREKEVIPNEKLHRDDVINIQFTSGTTSSPKAACLTHHSILNNGHSIGSRMGLTPSDIVCCPPPLFHCFGSILGYMATATHGSTILFPSPAFHPAATLQSIQSHGATALYGVTTMFLAELELLASGAIPQTGFSTLRTGIAAGSSVPKSLMQKLHHELNLTGLTICYGMTETSPVSCMTTPTDPMDKRLDSVGRVLPHVSAKIVSPSHPHEILPLGHQGELLVSGYLVMKGYYADEERTREVLVRDADGRVWMRTGDEARMDAQGYVEVTGRIKDLIIRGGENIHPVEIENAILGVEGVADVSVVGVADRSGGGGVKTYQGEDSTACVRRHLSGHLVPRYVFWTEGYPKTASGKIQKFKLRERAEWIVGGGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1V0</accession>
    <name>A0A5N6K1V0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008892</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1V0"/>
    <dbReference type="OrthoDB" id="10253115at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF30">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="48"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="504"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="589" mass="63547" checksum="03C550759F59260A" modified="2020-04-22" version="1">MGAGNRLLRLRGAMKGARIQGRGLLTESYSVGSAEPPLLPHTIPEHFHRIVEQHGSNLALVSHAQNAKLTYRELDERSNVLAHGLRALGVGKGDRVAVSLGNGWEFGALTYAIWKLGAVLVPLNPAFNTKQVESALNHLGTSHLVIGRETHLPFKNPRDNTPLLEDLIGDLAQANWRSETVPSLRNVVLVHSAEGDGSAGFASTTPFRDLIQGYESQREKEVIPNEKLHRDDVINIQFTSGTTSSPKAACLTHHSILNNGHSIGSRMGLTPSDIVCCPPPLFHCFGSILGYMATATHGSTILFPSPAFHPAATLQSIQSHGATALYGVTTMFLAELELLASGAIPQTGFSTLRTGIAAGSSVPKSLMQKLHHELNLTGLTICYGMTETSPVSCMTTPTDPMDKRLDSVGRVLPHVSAKIVSPSHPHEILPLGHQGELLVSGYLVMKGYYADEERTREVLVRDADGRVWMRTGDEARMDAQGYVEVTGRIKDLIIRGGENIHPVEIENAILGVEGVADVSVVGVADRSGGGGVKTYQGEDSTACVRRHLSGHLVPRYVFWTEGYPKTASGKIQKFKLRERAEWIVGGGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1V1</accession>
    <name>A0A5N6K1V1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1V1"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="139" mass="14835" checksum="3C913BA2143488EA" modified="2020-04-22" version="1" fragment="single">MPFSLLTRRSKPKPSTEDNETDKCHVPIEKQSGNTEKPLPATASAPVPPVSSSLNPDLPFIVPLQSPSDPEKISEQSSNSPSLNSPYPKVRAVVSNTDDPTLPCNTVRAWCIGLTLTTVGAGINCLFNLRSPSIAITIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1Y8</accession>
    <name>A0A5N6K1Y8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1Y8"/>
    <dbReference type="OrthoDB" id="415358at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF99">
        <property type="entry name" value="BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="139"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="339" mass="38266" checksum="E13E59B5E8AAAEFD" modified="2020-04-22" version="1">MDPPPSDPIAELLTTYNELNSPIITVLDEAPSALEFMRFVSLNRPFIVRGFASDWEATTTWSLSHLKSTLSSNQVNVAVTPHGNADSPTPNEEGNVVFVKPWEESQSFPEFVDFVSQQELRGRKEGEDILYAQTQNDNLRNEYSSLFSSVEKDIPFARIALQQDPDAINLWIGNSYSLTSLHKDPYQNIYVQVLGQKHFTLLPPLFHPCINEPDTPPTELPIATWDPDNPSVNPTKYSHLAQPMHVTLKPGDMLYLPALWYHKVGQSCSEEGICVAVNYWYDMDFGGSFWPLCNFVRNVPKTNPRLRFYPISTCVSYSPNSYVRCVCNATPSISQIAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1Z7</accession>
    <name>A0A5N6K1Z7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxyisobutyryl-CoA hydrolase</fullName>
            <ecNumber evidence="3">3.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">3-hydroxyisobutyryl-coenzyme A hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_008971</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20888"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57340"/>
            <dbReference type="EC" id="3.1.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.4" evidence="3"/>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1Z7"/>
    <dbReference type="OrthoDB" id="1737613at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000026">
        <property type="entry name" value="3-hydroxyisobutyryl-CoA hydrolase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004127">
        <property type="entry name" value="PRK05617.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176:SF3">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="7">
        <location>
            <begin position="56"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8296187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="514" mass="57317" checksum="72C8573B67D51DEB" modified="2020-04-22" version="1">MPLKAKVINPAFAGRAQMATASNVPPKGISYAQTENIKELESDEKEDVLFNTLYGVRTIELNRPAKLHSLNGSMIRKIVPRLQEWSKSDMANVIIIKGSGAKAFCAGGDVVALAEDNTKGPEGQARSTDYFGLEYKLDHLIATYQKPYIAFMDGITMGGGVGLSIHAPFRIATERTVFAMPETTIGFFPDVGASFFLPRMAGSVGTYLALTSERLKGVNAFYAGIATHYIHSTSLPALEKRLAELRFKDFENLEQRAQLINSTIEEYCTGLPHDEPIFISGELRKAIDRNFSKASISEIIAGLEGDIAVLKAKAAEVGLDDVEIQIGEWLEKTLTTLHQRSPTAVHVALRQMRIGKDWSITETFQREYQIAAKFMRHPDFTEGVHSLLIRGKNSKEASPPQWQPKSLEDIKPEDKIADPFFQVEGSQRIKLLSDRDYNEYPFKFGVPREKEVEKFVRQGGKSKFQVINHFFQATEGKQGVKEVVSEIIERKTTKSEAGHLLWEQEQVASPTSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K276</accession>
    <name>A0A5N6K276_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_009025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K276"/>
    <dbReference type="OrthoDB" id="5398391at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3330.10">
        <property type="entry name" value="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018020">
        <property type="entry name" value="OHCU_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036778">
        <property type="entry name" value="OHCU_decarboxylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37987">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37987:SF1">
        <property type="entry name" value="OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09349">
        <property type="entry name" value="OHCU_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158694">
        <property type="entry name" value="UraD-Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase" evidence="2">
        <location>
            <begin position="78"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="129" mass="14141" checksum="6B03FEC420144F52" modified="2020-04-22" version="1">MSGTINPIPSIAGVPSLSTIERASILDALFEPCTALHTLSLDLLHTTAFESYNDLIASVGVQLIELSESALPSDKECVFVNGRSRPVIFEDMQRRISRGDINFERREAIQAMCDIAADRASKLQTYKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K277</accession>
    <name>A0A5N6K277_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_008926</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K277"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8296134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="202" mass="23390" checksum="9A85B3BAAFFF3344" modified="2020-04-22" version="1" fragment="single">MTQAQFFLQDLKLGNYLKIPPRTMFFAQCVAAFWSSIVQIAVMNWELSHIPEICTPSQPNSYTCPDPSMFFTTTIIWGVIGPSRIFSSPESYYQPLLYYFLLRAILPVVSYVLARAYPRSSLKYLIVPVMFGGLQILPPATGYDFLCWGLVGFIFQYWIRRRWRGWWERYNYVTSAALDTGLSLCTLLVFFTLELTNARPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3Y7</accession>
    <name>A0A5N6K3Y7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3Y7"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF19">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="469"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="500"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="534"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="546"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8297066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="591" mass="64485" checksum="178CDBDBC9795793" modified="2020-04-22" version="1">MLHISLLTLSFTSNTRFCLGDCRLSRFDFVYYHPRSAILLVLKSSHSGKGTARSSRNIIASQLFSASPIFAIFVASRYPIHSCNTSRVITSCYLLLRGLSARLQLNGIMTESADTYFDPDDVVPRDSPMFKPMHIIYEPEPSPEAHPPPPISPESSPGGRKGGRRSSNRTYQADAVLVSYMGGGKRPDIARNAGNEALPSCEDEDDESPVRGTAVEIPGHEFSPGRTNLDITRKMAADAVDLLRAHEDQAFKNFRDNSQGSIGEAPTVSKSLATTNTSLHAQSATDIPKFSPHSLEPYQKAAPEANIQVETQSSLPPGELPPMRHSPQSGLSNGNGNQPITLPSITPLLGDLNKHAEAAPTPNETSFSQSPGRPTTRFAPGPGATSPARSPNNFRREMISPGRPSFYFVSGNPRRPSQSDGPHYIAAGDYSSSSNTETPSTDQLGSTPATMGIDRMSIDGITNPQVGGFQCTNPGCTAPPFQTQYLLNSHANVHSSNRPHYCTVKGCPRGEGGKGFKRKNEMIRHGLVHDSPGYVCPFCPEREHRYPRPDNLQRHVRVHHTDRDKDDPQLREVLAQRPEGPSRGRRRRGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3Z1</accession>
    <name>A0A5N6K3Z1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LAGLIDADG endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3Z1"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024995912" description="LAGLIDADG endonuclease" evidence="2">
        <location>
            <begin position="16"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="9243" checksum="27C78D1C4571E4A3" modified="2020-04-22" version="1">MKLATLLLMVIYAKGEHTSTYGGELDHYNAVQQSLITTWSYCSDWSRRLNFNLLLPIWCLFSKVSVIVAIVFGFFCFKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3Z4</accession>
    <name>A0A5N6K3Z4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphatidylserine decarboxylase proenzyme 1, mitochondrial</fullName>
            <ecNumber evidence="12">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 1 beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 1 alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="12" type="primary">PSD1</name>
        <name evidence="14" type="ORF">EYC80_002443</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="12">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Phosphatidylserine decarboxylase 1 alpha chain</molecule>
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Intermembrane side</orientation>
        </subcellularLocation>
        <text evidence="12">Anchored to the mitochondrial inner membrane through its interaction with the integral membrane beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Phosphatidylserine decarboxylase 1 beta chain</molecule>
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Single-pass membrane protein</topology>
            <orientation evidence="12">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="12">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="12"/>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3Z4"/>
    <dbReference type="OrthoDB" id="4330at2759"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016540">
        <property type="term" value="P:protein autoprocessing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03208">
        <property type="entry name" value="PS_decarb_PSD_B_type1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033661">
        <property type="entry name" value="PSD_type1_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF6">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11 12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5029078816" description="Phosphatidylserine decarboxylase 1 beta chain" evidence="12">
        <location>
            <begin position="1"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5029078818" description="Phosphatidylserine decarboxylase 1 alpha chain" evidence="12">
        <location>
            <begin position="382"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="topological domain" description="Mitochondrial matrix" evidence="12">
        <location>
            <begin position="1"/>
            <end position="8"/>
        </location>
    </feature>
    <feature type="topological domain" description="Mitochondrial intermembrane" evidence="12">
        <location>
            <begin position="8"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="130"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="185"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="12">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="12">
        <location>
            <begin position="381"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="12">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8297047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="433" mass="47989" checksum="D35E1167408183D2" modified="2020-04-22" version="1">MMEIKKDPKRGKGQVQVMSTLPLKAMSRIWGKFNELEIPYYLRVPGFKLYSFIFGVNLSEVSEPDLHVYPNLASFFYRTLKPGARPLHPNPNALLSPADGRVLQFGAIESGEVEQVKGMTYSLDALLGTSKPATTPNPADPSNIFTPSQDTTPKQSKARYSDGDEEVIKQDEKFATVNGISYTLPNLLSGPPQKQPGKKTSDASTTPKAASEAEVRADLALGEKPWYSRVTTENKTALYYVVVYLAPGDYHRFHSPTAWVAEKRRHFAGELYSVSPYLQRTLPGLFTLNERVVLLGRWRWGFFSFIPVGATNVGSIKINFDRELRTNSLTTDTAADRAADEAAKRGESYSGFAEATYEAASPILHGHALRRGEEMGGFQLGSTVVLVFEAPKGQRPSLDEGWMGQKRKGGWNWAIEKGQKVKMGEQLGWVDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6B5</accession>
    <name>A0A5N6K6B5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_001822</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6B5"/>
    <dbReference type="OrthoDB" id="166134at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15761">
        <property type="entry name" value="FYVE1_Vac1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15737">
        <property type="entry name" value="FYVE2_Vac1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.20">
        <property type="entry name" value="Rabenosyn, Rab binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021565">
        <property type="entry name" value="Rbsn_Rab-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036531">
        <property type="entry name" value="Rbsn_Rab-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11464">
        <property type="entry name" value="Rbsn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140125">
        <property type="entry name" value="Rabenosyn-5 Rab-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="9">
        <location>
            <begin position="186"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="9">
        <location>
            <begin position="324"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="561"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8298052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="646" mass="72651" checksum="CF4D50C1353EC13B" modified="2020-04-22" version="1">MSSRKLGGGRILGSGKSLAPPTPHTHQRNSSFITTSESTLSLGSSHSTSPITTSTLPNDIQDLSSRVSLENGRSTSATAASSKLLCPICSEEMMTLLQLNRHLDDNHQELPEVEQDEVKNWFDKQKLKGLDVFESNDVPISSNPIPNVLSGNRISTPELSRPDPDEVITRTHWQKSGFNDICTEPICGKRLGAVNGSVNCRKCGRLFCEDHTMYQIKLSRSAQHEPVRGLWCRVCETCFKSREGYNDHNGYTRDHTNDFMAMRRKHVDRAYLEISRLEKRLTKLTQLLANPPEDLAGNGSLLSLAGQKNSRKVLEQSVVTWEEDAKVPKCPFCQQEFGSWSFRRHHCRLCGRVVCSDPRTGCSVEIGLNVAAITDVQSEKHSENVSLDIRMCRDCKTTVFSKKDFQAELMEKTPSQRAYENLLQFEKGIRLLLPNFQRLLVALQDPEKPPSHAQLAEAAKVRKRLIDSFGKYDQAGRRIRDLPTTSATQQKIQKAIYQQSSSFLHLHMLPLKSLPKVLKHATPSSSHSSLLPQNGRSALSNIKYNDTTTETSSQVSDFSQISQMEQEEKELREKLIVLEEQKFFVQEMVADAGKRRKFDEVEALRTNLSDMQREIDSVNGMIQQLDFEGVYKREMDGGGGALGLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6D1</accession>
    <name>A0A5N6K6D1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001837</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6D1"/>
    <dbReference type="OrthoDB" id="329272at2759"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="180"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8298072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="308" mass="34831" checksum="6CBC1CA5CA7158E7" modified="2020-04-22" version="1">MTTSNLILTASSPTTSTPTPRITPPHKLSIQLPPHPHVHTWNRHLPSYNQAHCSEIPIFKDACYVREQVFVHEQQVVPLVHHLDPDDARSVHIVIYAPENSEPEDIISGDSRESFQSKYVPVGTIRILPYPDHARPLPNSSIVAPPPTTNEELLHSSIFFNLPPPAYESTVSSALHDGIEPYIRLGRLALLPSYRGRGYADLLIQAALKWASENPRFSYEMLREEEKKRVPEWRGLVCLHAREKAVETWGRNGFLVDEGMGTWWEYENTQTPIRCMALAHTINGIIQKTQLLPGSPSVNNIPPTIFRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6E2</accession>
    <name>A0A5N6K6E2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_001876</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6E2"/>
    <dbReference type="OrthoDB" id="5376590at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051169">
        <property type="entry name" value="NADH-Q_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42913:SF3">
        <property type="entry name" value="64 KDA MITOCHONDRIAL NADH DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42913">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8298116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="29539" checksum="959C981D4CE81316" modified="2020-04-22" version="1">MLLRRPASSLVRIGVNQSSLLRRSASSSFNQSTLPFSSQLCRSFSTNPKRSLTAITNQTKCTKFPRTQNIRFVSGKPLPQPRSKALNFLYRSATLLGGSLIILGVGVIGFFVYDATTYREDLSYSDISISKLALSPRRGGPKNLPIAEVQIDDDDSDEMQKQKDKPKLVILGGGWGSVALLKTLNPDDYHITLVSPTNYFLFTPMLPSATVGTLEFRSLVEPIRRIITRVKGHFIRATAEEIEFSEKLVELAGKSPDGKEGWKTVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6E5</accession>
    <name>A0A5N6K6E5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_001669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic/archaeal RNase P protein component 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6E5"/>
    <dbReference type="OrthoDB" id="24745at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3250">
        <property type="entry name" value="Ribonuclease P, Pop5 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002759">
        <property type="entry name" value="Pop5/Rpp14/Rnp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038085">
        <property type="entry name" value="Rnp2-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01900">
        <property type="entry name" value="RNase_P_Rpp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160350">
        <property type="entry name" value="Rnp2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8297877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="99" mass="11157" checksum="198015701132B171" modified="2020-04-22" version="1">MVRIKNRYLLVNILYPELEKNSSSKDKLPDVVLFNQPTVDALNARALLRGIQMEVANLFGDYGSGAIADSIAGLFFLLLHTFHDEEQFLWMGANKIGMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6E6</accession>
    <name>A0A5N6K6E6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">V-type proton ATPase subunit D</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">V-type proton ATPase subunit d</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10 11">Vacuolar proton pump subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_001907</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Vacuole membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6E6"/>
    <dbReference type="OrthoDB" id="7676488at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016471">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3240:FF:000002">
        <property type="entry name" value="Vacuolar atp synthase subunit d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="V-TYPE ATP SYNTHASE SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="266"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="268"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8298154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="317" mass="35451" checksum="347BB8341E0AFB08" modified="2020-04-22" version="1">MRSAKLTPSRAWTLALGSNNIELKWAESLINNQQSTSYQPPLSTPTLYTLERKAAKMSGAGNREAVFPTRQSLGLMKSKLKGAQTGHDLLKRKSEALTKRFREITRRIDEAKRKMGRVMQIAAFSLAEVTYAVGGDIGYQVQESAKSARFRVRTKQENVSGVFLPAFESYTTEGNNDFGLTGLGKGGQQVQRCRETYARAVETLVELASLQTAFVILDEVIKVVNRRVNAIEHVIIPRTENTIKYINSELDELDREEFFRLKKVQNKKQRDTAAQDAEMKAKKEAAAEKDKANGSDKENSTHTGDILGDEEDADVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8B8</accession>
    <name>A0A5N6K8B8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001169</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8B8"/>
    <dbReference type="OrthoDB" id="3548922at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="160" mass="16867" checksum="139D93EC7C77C57E" modified="2020-04-22" version="1">MIEDGTVGELTPESFPKRLAQTQYRDNTTIFHTQATETLLRNPSPHFPAAIPNNGAVSIPNPDGTSDTAELWKKGNAPVEIPNGDGSTDTAELWKKGNAAVSIPNGDGTSDTAELWKKGNGAVEIPNTDGTSDVAELWKKGNGAVGIPNGDGSEDIAELW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8C1</accession>
    <name>A0A5N6K8C1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8C1"/>
    <dbReference type="OrthoDB" id="421009at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="90" mass="10073" checksum="FC8C06075AC4E8A5" modified="2020-04-22" version="1">MHTIPQYLLISSSYISLIHNKHTPASTFLSSNHNPISHDPPPSPTLSNTTTIRAPVNQRNVTSNLEPRTSNLANKETHPRLLIHQDNQFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8C4</accession>
    <name>A0A5N6K8C4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8C4"/>
    <dbReference type="OrthoDB" id="2555434at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38646:SF1">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38646">
        <property type="entry name" value="YALI0F00814P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11176" checksum="937F6A047B6E7161" modified="2020-04-22" version="1">MSSHGLGRFVGMFEPHPEDRLHLRLHRARSVILTAQELVEIRAAQRTFEGAYIRTALGQFSFALVVLKIFTAEFYSIGALFATYGAGVLMVSLYRRLET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8C8</accession>
    <name>A0A5N6K8C8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8C8"/>
    <dbReference type="OrthoDB" id="4150019at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="302" mass="32649" checksum="85637E576E47D7FF" modified="2020-04-22" version="1">MQPNLPYHLNMPVIQNLGGVQTKKETTEGFSPDNKVTSSQNFDYSGGPPAWMASEVSPGTKTPADMTGNYWPTSSQESPMTPGFSPYVAPNMHMGNAQNWQSRGHHGQSEASSREPEWPLPQRSVSYSNLEGMQTSSQHSAYVAPQPTDPYASVRTRAHNGAMYPHNTTTTHPHSAAEISSASTIGTAYTNSVTPMPTGSYTGWNQPYSNGYAKVSSGIDTYNSWNGGQGGQRIVEEEENAVGYSGYANPGGGKEHIMDHGQIFGLLAHENWLLSRHTLTNAATGVTFEQGKIDKGFLSAQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8G6</accession>
    <name>A0A5N6K8G6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_001208</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8G6"/>
    <dbReference type="OrthoDB" id="186625at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048306">
        <property type="term" value="F:calcium-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16180">
        <property type="entry name" value="EFh_PEF_Group_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051426">
        <property type="entry name" value="Peflin/Sorcin_CaBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212:SF3">
        <property type="entry name" value="GH27120P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212">
        <property type="entry name" value="PEFLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13405">
        <property type="entry name" value="EF-hand_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="190"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="226"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8299089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="292" mass="33290" checksum="601EB0332EF0EF84" modified="2020-04-22" version="1">MAYNKAFNPDSLPAFAEPERKNTQSPSIQTSIQSPVHSQAQQAMYNAQYENRPSPVQTAHPIDRRPDGRRLSPQMHPPANYGVSPPNRGYASPPPGQFQAGRVAPQTRPAQYSRPTHSPAPPGADPQLWPLFQAVDKDRTGALTEKELRAALVNGDWSAFDPYTVKMMIRMFDTDRSNTINFEEFCGLWGFLASWRSLFDRFDKDRSGNISLDEYSEALVAFGYRLSESFVATLFNAYDKRREGAISFDLFVQSCISLKRMTDVFKRYDDDRDGYITLSFEDFLLEIIRQKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8H2</accession>
    <name>A0A5N6K8H2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Altered inheritance of mitochondria protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AIM11</name>
        <name evidence="7" type="ORF">EYC80_001191</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AIM11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8H2"/>
    <dbReference type="OrthoDB" id="10025998at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038814">
        <property type="entry name" value="AIM11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043729">
        <property type="entry name" value="DUF5672"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39136">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39136:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18922">
        <property type="entry name" value="DUF5672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5672" evidence="6">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="127"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="383"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="399"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8299067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="412" mass="46534" checksum="3D92C314BAC4635B" modified="2020-04-22" version="1">MAVTGGNGGLSLRHIPPILKVTEKESRKPGDPWEDRWICDRLLELDPKKMPGPEIEATFSVESQWYERPFGYHLIGSGKNLVSGIWENKERRKHILEYCPEIKIVLDMDLIRETEKLTKELEALKNPKAAAEKGKETEKDKGNEKGNEKGNEKEKEMEKEKGKENAIIFQNPEHEKIPNTSKTFQLQNSRVSNFESRYLLTPTFEVLRKTRPRTPKDQLMKFVQIPPTMAESRPTSSTTPPTASPALAPPDSSLFSQRSRRQFGLFMGGAGFVALSAFITRRALVRKYKAMLPKFYTPSNRVHEVDGSMEALEALSVATINVASISLMLTGGSLWALDISTVDDMRQRYRAKMGLLAQETNPEDEKQMEEWVATMMARLNIDPKEYTAEKGEKALEGNEGQTDDGQGQTKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8H5</accession>
    <name>A0A5N6K8H5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8H5"/>
    <dbReference type="OrthoDB" id="1747771at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="83" mass="9627" checksum="97BB9AA1C49E5E91" modified="2020-04-22" version="1">MEAAPFQPAWYEGPTNEFSPLGTLDSIIWVLHRSIIIVYHIKSIFYTCAKRSGLSNSPKNSLLNWYITYLFPIPVFKRHPNTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8H7</accession>
    <name>A0A5N6K8H7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8H7"/>
    <dbReference type="OrthoDB" id="5428259at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="290" mass="32366" checksum="20EFAC0052564F28" modified="2020-04-22" version="1">MSKNHTNIPLHCSICPKNPQFSDVSHLLTHTSSKAHLSNYFKLKIRAASELTAKVQLDNFEDWYDTYDLERLLSERLASKDQKKAAKDKKIRNSKAMLPGRSKIKKEGNNTLDDESNLAPMFRAPVPRMHLWPTTTNTNIDNNTSTSNSDMGSEWDHNAMYSTPTSSRHIPGYTLQKTPSAVGTASVTTNLTTPMKEEGADAEIIEKLSDSAKLKGVLWPGMDLFDSATAEMKRMRNQRKDGSILELMMAASAEVQPTEVSYHPDGAFRTARNIFGPLSTETSPVRFSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8H8</accession>
    <name>A0A5N6K8H8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8H8"/>
    <dbReference type="OrthoDB" id="18042at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="348" mass="36439" checksum="45B61A7C07404C29" modified="2020-04-22" version="1">MAQEGEKAGMETNDPSTDNQAVGFSPSNKFKSLGQGEQSTKESSSPKLKARTNSHSLSSATGSGILASLNRKGKYAEPLIHTELNSERASISMPPPSTRPLLKSRTSSSYSQRSPAALEVLEEGINLGGIGTSHQDFAVEDSESLKSNPIMADDKGLKPNPTMADDNKNVPVPVPLPEPTLRPRASFTEMDGKRMSVSSMYSLTSARAGGVISSAASATGSDNGGSTRTTTASASSGKGPGLPQAETSNISVTTSSGGPNAPNGHQLTARESPAQAAELVKRNSVARGEAQPRPQPPQRSRSRAKRRFSGSTGASSHSPSSERGLHLKKDDEHKPAPWGWRIGQSVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8I0</accession>
    <name>A0A5N6K8I0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">Geranylgeranyl transferase type-2 subunit beta</fullName>
            <ecNumber evidence="3 11">2.5.1.60</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_001216</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="3 11"/>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8I0"/>
    <dbReference type="OrthoDB" id="5428259at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02894">
        <property type="entry name" value="GGTase-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000012">
        <property type="entry name" value="Geranylgeranyl transferase type-2 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026873">
        <property type="entry name" value="Ptb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF11">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="12">
        <location>
            <begin position="22"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8299099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="292" mass="32153" checksum="6B1E7B986E96A5BD" modified="2020-04-22" version="1">MALVSGPGRAGSTALPEELQLAIEPHVKYIQSLDSRKDELEYWHTEHLRLNGLYWGLTALHLLGRPDALPRRETIDFVLNCQHENGGFGAAPGHDAHLLYTVSAVQILVMVDAVEDLEKNLDGKGKDLVGKYLADLQNKDTGTFAGDEWGEEDTRFLYAALNALSLLHFLHLVDVDKAVNYIVSCANFDGGYGVSPGAESHSGQIFACLGALSIAKRIDVVNIDKLGRWLSERQVECGGLNGRPEKVEDVCYSWWVATSLAMIGRLHWIDGEKLTNFILKCQDTEEGGFADC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8I2</accession>
    <name>A0A5N6K8I2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8I2"/>
    <dbReference type="OrthoDB" id="5406427at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="467"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="579" mass="63483" checksum="C8D927955C0FE908" modified="2020-04-22" version="1">MDKEHGTNVSNSSPPSPKFDIVDVHHMSTIEPSSSRRSSISRKSGKKQKKVKSWAGSILSRKSRSRGQKKKGGRRSATPPTRPYTAMSDSAALDIDIQPLPVHAEASPATEQQDFASWKPRQTSPPDDDAMSPIIDLDAALGPFNTPSSYGAEWQSSQKTSSKRRMHSAAGMGGFIGPGMHYHRRAESAPEMVPFENRFGIHHLGSSSTMADVFEEDEEDDEWEDTKASSDKDSVARTEDDEPNALGIDIKVVEVEASNSEKTMDWTVDESQGIKQKSSGASESEPKSVSVSLKSDHSITSLQDEPIMEEESVSPIQIADDSIPPRPDSGAQSSESTATPPFRPRPAKDLAPVEISPFSLQPAYLSPNSPHSTVYSSFPSPRSPFSYDTQRISTAPSSIGDENAFQSLLLGEPGPELRMSVDDVPSLTSSNSTMTRESGANPGFRFRDGQRSVSVSAASGPTRKRSSMASLSRLISSSHGERSKLSIESRAPSNPEMERKDKGNRGSKRISPSLVYTLAEHFALLSEISAFFRFQQARYRRITLTTLLHMHLDFPPRFGKTLAFRTRFARGSFRNVLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8I3</accession>
    <name>A0A5N6K8I3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_001197</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8I3"/>
    <dbReference type="OrthoDB" id="5382468at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12418">
        <property type="entry name" value="RRM_Aly_REF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051229">
        <property type="entry name" value="ALYREF_mRNA_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025715">
        <property type="entry name" value="FoP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965">
        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF82">
        <property type="entry name" value="THO COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13865">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01218">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="84"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="144"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="29"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="236"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8299075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="316" mass="36042" checksum="89DD2E5532F96657" modified="2020-04-22" version="1">MDRSLDEISGERQQQRGGGNRGRNGRRNNRNDYPRDGVRKPNRGDDSRNIDSEWVHDKYDDRNARSSNRPERREYEDERPSNSAKVLVENVHYDLTEEELEGLFERIGRVSFLKLVYDRAGRSEGIAYVTYEDPRDAQRAIAEFDGANANGQPIRLRSVPDGPSRGRGGRNQFQSSGRLADRMTLPRSRSYSPPIRHSDVSKPPPENVDRYVPGDRGDRGDRGDRRRRSRSPLPRRGRDGRRPGARRERGERNAPRGGEKPARDGRPKKTQEELDAEMDDYFGNGSKQEENVNGTTSEAPVSAQEPVQTDDIDMIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KA53</accession>
    <name>A0A5N6KA53_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KA53"/>
    <dbReference type="OrthoDB" id="4227028at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011431">
        <property type="entry name" value="Trafficking_Pga2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28199">
        <property type="entry name" value="PROCESSING OF GAS1 AND ALP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28199:SF1">
        <property type="entry name" value="PROCESSING OF GAS1 AND ALP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07543">
        <property type="entry name" value="PGA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="201" mass="22774" checksum="BA2EA66B47049069" modified="2020-04-22" version="1">MNRINTYFLFSSLLFCSVLFISFHGSSTSDISQVHLISLLSVALLTSFYDWCRVQLFTAINAINAINLLNSTNHPSSKYHSPHPPPLQTQSSINTVPKTRSKANSNNMAEFIVNLLEMGVTNFYRNATGAFQEMKTMELQKWIRIIAVVGAYLLIRPYFIKLGAKKQEAEYAKARAEHAQKKEKEKHIGANSFRDSLIRVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBW2</accession>
    <name>A0A5N6KBW2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_000472</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBW2"/>
    <dbReference type="OrthoDB" id="10259639at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012445">
        <property type="entry name" value="ATG101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292:SF0">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07855">
        <property type="entry name" value="ATG101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8300269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="186" mass="21327" checksum="1DD6EDAA6DE9DE98" modified="2020-04-22" version="1">MDPRRAPEYIIEVFADPTSVREVIRGILHTIFFHRFFPSIIPKTRDVLEMTLPYVENVEIETLIDQRTAALVREIDTSSDLGARNTGVRGQMAVQFFEKKRRKAWFTKGEEEVCWEQWTLDVTLATPRTESERAKVRSAMEAMLLKAAMKIVTTVSMEKDHIPPITTSEANPDMPDTWVQALNSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBW6</accession>
    <name>A0A5N6KBW6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8300916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBW6"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="567" mass="60693" checksum="0B248C4354E65FC1" modified="2020-04-22" version="1">MGNDPRLRNSDMSQIVTNPSDGTILNLTDSNFSSSPLDNFSVLSGEWSKAARPPLALRQGKSGQNIDKRRVHRKSTTRNLDFALGDGVDKRISGIGHGARESISSFDALNVQGNRGSIGHGQHPSLARNSRTWKTVNTIDSDGDKHCSANSVYSTASTDLLKFGQATVSPSGGKEMLSIKTVPKSPLAPAPIWEQETGGNSRMSYSSIYTRPVSRRGGVSPFFSGGGMASVRRKARGSYAGSPTVPEEVHIGNELKAAGTGINNDSLGITYPNGYSSAKEGTRQLRSYIQATFSKSRLKGSDSMMSMDSRFDSVSPSMQELQISQGSTQSQGNISQSQNRRTQLLEIDRREQERGVGQENIDTGSDILLSEFSAGSWESMGESTDVDSQPNFIRHGTDTTIPQIPRLFATEGQSNRGRSSTLAIPSFSPFLSNPYSLDPEASGGTQTSSQHLNLRRSTETDLEQNQNERESREAREESPTMGNLIVGPNARMMMGAGRRPISVDARENKRISSTKAKIGRHGEGSSVTLGSLFGSVGSPPPSRGGGGGGKGKGNGNLGNEGDFSAYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KC78</accession>
    <name>A0A5N6KC78_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_002963</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KC78"/>
    <dbReference type="OrthoDB" id="3543352at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="130" mass="14021" checksum="31A287D90A3B0152" modified="2020-04-22" version="1">MQSEQSLAPVLSTILVTNPVTGEVSEVTGILQQTRGPVATQMPSAYLEQSPGSVTGFTAFPPRPTMFGKSFSNSDSEDVLKATAPVFTPCHQRNVSSTARSALSPVYHRQNAQQEAIQARLNKSLAEQRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KC80</accession>
    <name>A0A5N6KC80_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_000569</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KC80"/>
    <dbReference type="OrthoDB" id="269151at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1580.10:FF:000009">
        <property type="entry name" value="Mitochondrial GTPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782:SF4">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="4">
        <location>
            <begin position="69"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8300389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="280" mass="30538" checksum="A749E1ED68CF8BCE" modified="2020-04-22" version="1">MLSSIDLIIECRDYRVPLTSRNPLFEQSLAGRERVIVYTKRDLGSHGLAVDKKRETQHGLAHDSLTGSRILIVGMPNVGKSSLLNALRMAGVNRGKAAFTGAQPGITRKIASGVKIVDPDPETGTEGVYLVDTPGVFVPFVPDTESMLKLALVGSVKDTIIAPTTLADYLLFHMNLKVGGRVYGEYCGATNDVVEFLEGVCRKTGRLGKGGVPDLEAAALWVVQRWRQGNLGRFVLDEVEVDGLERKVAEEVRMSVSQARKQAKDVQRMRAKTKKSDSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KC94</accession>
    <name>A0A5N6KC94_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_002983</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KC94"/>
    <dbReference type="OrthoDB" id="5402974at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060962">
        <property type="term" value="P:regulation of ribosomal protein gene transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045178">
        <property type="entry name" value="Fhl1/FHA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21712">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN FHL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21712:SF29">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN FHL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="365"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Fork-head" evidence="6">
        <location>
            <begin position="713"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="3">
        <location>
            <begin position="713"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="78"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="476"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="549"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="792"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="897"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1095"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="481"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="587"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="642"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="840"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="898"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="949"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="980"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1106"/>
            <end position="1138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8301063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1138" mass="127281" checksum="CF7C5FDD815FDC52" modified="2020-04-22" version="1">MTSSKTAETVTQPVAPVATMSTTTFINDNNPLGTHLTDPQDNAKYFFAEQDEAVTAAMDPTLPSNSTRQLEPLLENRNSSAAEGFDSAKGTEKSELSNHSDNKISSHPEEPLDSVMEHYDPKIEQDPNGKEAIDHNPEINTHSNIEPTAQLIQKHSQSPANRPLDTLPLCDISSALPGNDQMLSSNYEDTCQRDTGNIDPDDMFRGMCGVDESMGPDFKGRSWLPEHMNLANSGVQLDGFAKLLFDDSTFYMTTHEVIIGRDTVAQNNLLRYEKEQALIERAWNESGLGPDGSSQTAIDSNMPRQTIININPRAGILESWMSLHHEKRSRKGKKLKNQTSQIGTGARLPAASGNMPLQNPDPHSCPVVRVHPPFDKGLAGFKAISREHVRIFYDDHQDIFKVEFLGRNGGFVDGLFYEPKQVATLKSGSKLQMGFIYVTFALPDLVIDDTSFQYHDEAQEEAATGTIYSEGGKEMSLSFDDVPRAGDQRSTDNSECSSDYRNGYNVAELSDNEEERIEGGSILDFAGNSDNGLQDLEDEDNSLLDDLEHEEEKSIQEEPLVNQPIDTSPQPAKKRGPGRPPKNGVMSKREQQIAKKEALERERIQEEERAQEEQKAEDQAQGTASKTVPGKNKVGRPRKHPRPEVTEEGPPRQKRKYTKRQSGPKSPASPDEDKFDDDGNCIQAKSGSTRKVAYTLKEVSRNKADYTAERLEKPHRNYLQLVYELLEEAARPLCLPQIYNEMEVKFPYFLFQDSKGWQSSVRHNLGQHECFERTKRAGKGWAWTLKPGSSYMKEKKKKERSPPVAGGNQPIYQAGHPIPGYGVNQMQPPPGYMFNPQLYQSQMNPHQQQEHQQYQQGQPYMGHPNHHYAPYPMHQGYVPPPGIPAPFMPPMAPQLGGTAPASYSSPYAPKPPAATTQSQGHQQQPQGTQQPQGSQQPQGTQQPPPQQLQPPQHQYPQQQYSQQYPQQPQQPHYQPQGLPSHSNVSQAQVPQHQPRPSAGNSIQPPPQAIPQTAAAHTHQKRVIPPNLIAVVQGYRNHVVNLMRQKAPQSDAEALVDKAINRVYDGTEEDRSLDSTEHEMKLINGVLNVLKLPLVPRAPSASPGHTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KC95</accession>
    <name>A0A5N6KC95_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SART-1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_002981</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNU66/SART1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KC95"/>
    <dbReference type="OrthoDB" id="5583at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000481">
        <property type="term" value="P:maturation of 5S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045347">
        <property type="entry name" value="HIND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005011">
        <property type="entry name" value="SNU66/SART1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152">
        <property type="entry name" value="SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152:SF5">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19252">
        <property type="entry name" value="HIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03343">
        <property type="entry name" value="SART-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="203"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="320"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="391"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="442"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="553"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="640"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="220"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="320"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="400"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="553"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="649"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8301059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="697" mass="77984" checksum="66CDD8F7C771BBE3" modified="2020-04-22" version="1">MNGALLKHIWNLTSSVHSSTESAEATQNTLNITMVDAISIEETNRIRASLGMKPLAVPGAAGPVFKEAPSAPVEDVGSTLESRQAEGYDNYRKLQEAEENKRKREAKAEAIKKARDTAKRFAKLEGKGLGEADDDGDLDAKAWLMKQKKRQKEIEKARKKEQERAEAEAAAAAEYTAKDLAGVRVGHELDTFAEGEDQVLTLKDTTIDENEAEGDELENLELREREKLSDRLELKKKKPTYNPNDDDESGERKILAHYDEEIDGKQGKRFTLDGMGSTTEAALVNAASTKKAKAKTFSLDILKDDEPKSDYLDISDIKVRKPKKKKAKSTRQKAVDEDDVFPESEPAVSNGDGADAMDIDQGAKPIKKRTFEDMSFVDDDDLQALLATQRRNALKKRQKVRPEDLAQRLREEASATPAAENEEGNDSGLVIDETSEFVANLHKPVAPEPKQRSGSRPTDGVTSMDADSDDDGDVKMNESYANIEDDEDRLARIKREEANESIENNGLEKEATLDNVGLGSMLNILRGRGILKTSESGDAATIFREKQMFLAEKQRREAEAERRAKSQRERDRTTGRLDRMSAREKEEHARQQNTMRDQQESRQLADHFNKEYKPNVELKYIDEHGRHMNQKEAFKHLSHQFHGKGSGKQKTEKLLKKIEDEKRREAQSALDGSQIGGMTGAAAQQLKKNRQAGVRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KEC1</accession>
    <name>A0A5N6KEC1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_005470</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KEC1"/>
    <dbReference type="OrthoDB" id="5342292at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF124">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="92"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="203"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="266"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8302018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="304" mass="33511" checksum="DA42C98CB0FBB2C7" modified="2020-04-22" version="1">MASQIAAIPAPEGYVVNFDDPARYGELAGNFAVEDACLIVAWLCGVTVQAILVSMWLEKIVGVHAWEISIEKYNMYSKAYPNFLSYSFTIGYHHFAIIFALIFPCHPVAMNWDVTITDGKCVNRAATYTATAAMNIATDLALLTLPIPMIADLRMPRVQKVGLIIIFVVGSFTVEANLVIICGSFPLIRQFFKHIAPRWIGENSSSKVNSSAHPYDLETIGQKSSKKNRPSRRAYGIESLDDIDNDLELDGRFTEHKVEIAAGNRADSGCRGRVSDSDGERGDAGSETHIVQTNVTNVSFSRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGA0</accession>
    <name>A0A5N6KGA0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGA0"/>
    <dbReference type="OrthoDB" id="5429770at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF1">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="353" mass="40665" checksum="3FD55912660C5091" modified="2020-04-22" version="1">MANEVLKTPGTATRDTTLMASLLLDFLEKIINSEPRSSKSWTIHTEGALTMVKLRGLDEFIDRSQICMLMRLSTHYTVSCIASGSPLLETLITLHNFLGNQLGTQDTGFQLADLIMFGYASLCSKTREDTLSFDEIIEWSIALDRKLKRFYFRLPTRWQHSVFYSDCKTDRAFDPYYDLYPDANTCQELNMHRIIRILLNNFFMDHCPTSLAINQYMALMDSIRTSVHEICASVPQYLDCKNAARQRLPVSDFDQSSTHRHHTPDHDLDCCTLIFPLYVVGQSNIISGARSWVIEQLSYMSDHFRIKKAKTIADILEREPTLDPRLRRCSLFLAATPLYLKRVLFSVVTRMFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGD0</accession>
    <name>A0A5N6KGD0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MDM20/NAA25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGD0"/>
    <dbReference type="OrthoDB" id="1874341at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019183">
        <property type="entry name" value="NAA25_NatB_aux_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF3">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09797">
        <property type="entry name" value="NatB_MDM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="654"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="654"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="682" mass="76975" checksum="2CFC27764D089ECF" modified="2020-04-22" version="1">MSSDKSTVSPWDKETSQKFESKRPGEYFDPCQEAATRSLKCLARNGGDRDMCTDYFQAYRDCKKQWIEQRKEEKKKAGDRQDVPIWSAIEAGNFKQALKLVDKRLAKKRTSHLEAFKIYIRSRSSVQSEKDAVLAHLEDLVIKKAIITDQEDIDLYDDALVNAIPEAGSIWARTIGELRWQSVKAYPKQEDSGLKSFKACLSERDWEHAQQIASSLEKTFPNKHQYVFWNISSLFLRSMSSDLPIEKRTLWGRLAFGQISKLATATIQADKSKSLPTRAIHTPQELLLLQRITAAHGKLEDQLNYLNEPSLGPESIVAKGDWELWRNKLQLMEASEHWQQLFEITGDLLKRARMKDERGEIVEARMADWAVWQAYLRSALALRTPSTLDSVSNEIAAHLNPASGIDKTWRRNASLAWLEFTFKNSSTPFATETSGSDLEKHPRVAAIIKYLQDFGDATTAYSDLRLYVELLQTDERSRLLEVLRSGLQFGKTAKINDLEPELKALSISKNEFENANDMTRCVNLHKLTYLIMSSLPEHERRSSPLRKAGELSFTCTHCSSPCEVYCGVCLEQVSQNSIAAYTSAIDDNGKISKSLLPTDRHPADDFCTLAAMCLMKLSISGSSDADGSLKSKHVAYALQAAVFLEYGWSQSKSNSDFSLLLSSGPSQEPEKDVQRLPLPSCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGD2</accession>
    <name>A0A5N6KGD2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGD2"/>
    <dbReference type="OrthoDB" id="10001928at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000142">
        <property type="entry name" value="Regulatory protein ral2, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503">
        <property type="entry name" value="MCG48959-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503:SF2">
        <property type="entry name" value="NEGATIVE REGULATOR OF SPORULATION MDS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="449"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="529" mass="56621" checksum="64504000C2E69E70" modified="2020-04-22" version="1">MLIYSNYNFLDVKLELQVRASDGTLAEKPMHGSFSPPGLRFPNGGVIDTNFVVSGTYLTSSKQEYALWALDLRSLTWSRIDAGGSVFSQGSWNRGVLWNRRNTFVILGNRKRSLVEDYNHRRINFTNVCMVELEAFGLYDNPRKAAPMSGFVSASSPFTNPLLNINSKAGWNTGGRTLSKAAEELGQSALALRELADMDILCVGGERIPVNSRIIARRWGPYFVQLLREGTATQDGNDAATLRQESVFRHNPSRNSSVTITPTLGGQSSSLSTSSTLNSSDSAALALPPDSGSLPPNSRPRTLYLPHTQLTLQALLHFLYTSSLPPKNSTLCTPQILCSLLQLARPYKIDGLLEAVVERLHGVLDSRNAAAVFNASAMAAGGGRSTSTASDIADPWSLNRLSNGAETLMQLGLDNEISAHGQQSLRINTSVGDLGTGQGGRGQDDEESMSATSSAASDVSSSDLGRSVSASDSGRVNSAGEIWRGDISAVIGLQKRGLRGLMEGRRLRERGASVSAASSQRVGLGIANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGD3</accession>
    <name>A0A5N6KGD3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CHCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_006174</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the assembly of cytochrome c oxidase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGD3"/>
    <dbReference type="OrthoDB" id="1874341at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033108">
        <property type="term" value="P:mitochondrial respiratory chain complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051040">
        <property type="entry name" value="COX23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46811">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46811:SF1">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8302833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9556" checksum="98922F7BA7B48BF1" modified="2020-04-22" version="1">MSSDKSTVSPWDKETSQKFESKRPGEYFDPCQEAATRSLKCLARNGGDRDMCTDYFQAYRDCKKQWIEQRKEEKKKAGWFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGE7</accession>
    <name>A0A5N6KGE7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF2415 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006189</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGE7"/>
    <dbReference type="OrthoDB" id="20669at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991:SF12">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_8G05640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_8G05640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="546"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="731" mass="81547" checksum="8BB7CCBDD02511C3" modified="2020-04-22" version="1">MNSGAVERTNSADHIENDSSNGRALIGQPNPSYTNQPFALATPTTPSMIFSDPNEVHTSGNRSISGDLMEESDQDMSDGGAPLSLGIEESNSEMETVDDEIMGLENMVGLHYDSHSQPATNPFYTYGFSDGPHPPLEPGAISHLPEIHTPMLESINTTDLPAVMSEVSQQLQDIQDGQEHGGFELAPDEHHDLFINHNESTTPFDSLNFPDNFLTQPSISQGISFGPASTVAELEMWTTTTPIEAESIEWAISPARRSPNQPRARAPLQSATTSHCVASNLEPLRRCDLQGEECDIQRINWKDLGVTRLQARQRRQITYKNYTNLIYPNRPQLHPRQLHGIRLPNEDNYFRFRRMDFQHEVLIRHFQLRNLITCPSQSCVIYAGRTQIMHYNPTIGSAPSVLMPLGNSRLQSFHSGQNEYRISTLTSGHDIVVAGAFEGQYALINTRAQKGTKCIEGTITEHPNDITNHAQVHLSRSSSPLVTFASNDSGIRTLDVTTNKFISEHMYDYAMNCTAVSPDRRLRVLVGDTRKVMICNSDTGELLQELDGHLDYGFACDWSDDGWTVATGNQDMQVKIWDARYWNRPVTSIAADMAGVRKLRFSPLGSGRPILVAAEPADYVNIINAETFDSKQTLSFFGEIGGFDFTNDGQELMVANCDSSRGGIFEFERCDFATEGLCGKDEQIRYMLAGKKRDYRLSSMGEDLMEESPDLRGTTKRRERRTALLTDLGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGG5</accession>
    <name>A0A5N6KGG5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetylglucosamine-induced protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGG5"/>
    <dbReference type="OrthoDB" id="10053431at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022036">
        <property type="entry name" value="DUF3605"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020:SF4">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12239">
        <property type="entry name" value="DUF3605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="15759" checksum="5AD3577C2FFCD0B6" modified="2020-04-22" version="1">MRYILDVKLQWKEEEIAAGAKKVSFADENNLKVLLNDWPYGIDEKIVHLVVWTKFALEDDPETGDTREDVKREIDGWVDEVFGKRCGSENVIWFRNWRSLKSVHAVEHFHIMLYNPDPEFVKKVTKGDVPNQGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGG8</accession>
    <name>A0A5N6KGG8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006198</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGG8"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="67" mass="6944" checksum="3357EFB62D189D8C" modified="2020-04-22" version="1">MDLGFAMGDGFEQAMGITFGVGDIGNYFGEDIFGQFMGGSVPGFDGGLHWAKQSKAELSCNSGPSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KID0</accession>
    <name>A0A5N6KID0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Maintenance of telomere capping protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_004869</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in telomere capping.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MTC6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KID0"/>
    <dbReference type="OrthoDB" id="5573651at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051008">
        <property type="entry name" value="Telomere_Capping_Maintenance"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057530">
        <property type="entry name" value="TIM-barrel_MTC6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35518:SF2">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35518">
        <property type="entry name" value="MAINTENANCE OF TELOMOERE CAPPING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25506">
        <property type="entry name" value="TIM-barrel_MTC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="MTC6 partial TIM-barrel" evidence="12">
        <location>
            <begin position="35"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8303445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="569" mass="62583" checksum="0A56747A2D725EEE" modified="2020-04-22" version="1">MTVADSMTTSLESTVPTTSPIPSPPNNPLYRIGPYACTATINLEMLTSVLLDYIQKTQNTIDAHLLIVTLNIHAVKSEANIDGLTPRPLILPNALESLGSIFASNLSAYIYTPNDLMSNRANLNTSWYSVIERHRPVLDYYTTTTQEFGVISTEDGWPTEAYIEFSQGKRMLLQFGSVEPQMNKYNFDGDADTIFSQGYLDGHRGNDISASSDGTVTSGCLFVNTTEQVSQANSSWATAGNIPNFEYPTNATSNITSLLNLTSSLTSCGISPTLNTTLLNNTARTNDLPYKNYTQSSIWSWAPNEPRNFSPSTDNSDSLFRCATLHPTTTHWYATDCSTKLYAACRAPSQPYNWTLTTYTISYSYASQACPTPYTFAAPRTALENAHLTQTIRDLSPARNLDTTTTTVTTDNDPKIWLDFNSLDTKNCWTTGGPNATCPYTGREAIMDDITKKEILVPTVAALIVLILTGFVSHLVTDTRSHPKSLSRIGNFLNTPPIKTSQAISQGKFTPIPTLPHIPLISTPRLYPQVISAPGFPVPAEPFGCKSSPRTSFMYDLSNCSIRRFNSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KID3</accession>
    <name>A0A5N6KID3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KID3"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="91" mass="10571" checksum="2EB8918591541B45" modified="2020-04-22" version="1">MGKFCIIEARVERLLAGVVINVEGKLASYIQYNDTNRNRIYLADCICINMFVNANTMVGKNKQGENCLWPRWPFNFAQTFCQHNKHFQPIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KID5</accession>
    <name>A0A5N6KID5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KID5"/>
    <dbReference type="OrthoDB" id="3564711at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="432" mass="48657" checksum="BA51894444D70185" modified="2020-04-22" version="1">MCADETRSHLSKETVPYTPPQSEPTSPADAILALPTGLLQTISDLETHHSHHQSPVTNASVQIPPTTRGFHKSFLNGVFGPINCTLNNVPPSHIPNSVKWTEFFTIHLDTQPYIFPLPNPLQTYGQIVHFTSQSTTETPRATQGTTFPTILRLSPDVDQYYYLGHFVVSNVITTTSFDQVLKSLPENDENTKHTKHKLLKERDRALGSAATITRNMPVDFYTLQYVFFGEEQYKILVRAQERFEALKSANNTINSLLEPHFNHFEGASLTLAHQTRLTEPTTMTRKLPSVPVFESHTDINNHNTTGQSVQPSNKVFNEPSSMRGKLPYRTEYEKMSKSKEYSTMSPSFPRANESLPHGPAPVSRVQSSDATNKSLSDTNCHHVNTPSIPAPLSNKCRDESPTTKRKLTFGDDPRWKKKRGLDSMDVNRIREF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KID7</accession>
    <name>A0A5N6KID7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KID7"/>
    <dbReference type="OrthoDB" id="27652at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="138" mass="14999" checksum="2373E171FA6CEB4F" modified="2020-04-22" version="1">MRKAIALSKQTETEEVKRRQSEASNQRENNGTGSEKSESKGFGSLSLNRTHKGSKSMSRKSLGFLSGKNGEKEKEKEKEKNGENANIPESSSSANVNTAVEGMAGPQTPEKHEKIKKERFSFGGLGRKKSNLWSPGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIE1</accession>
    <name>A0A5N6KIE1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_004950</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIE1"/>
    <dbReference type="OrthoDB" id="20524at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033316">
        <property type="term" value="P:meiotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034501">
        <property type="term" value="P:protein localization to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974:SF21">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974">
        <property type="entry name" value="MIXED LINEAGE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8303543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="216" mass="24832" checksum="42FEA03552B967CE" modified="2020-04-22" version="1">MTYGRAPFGHIQNQLQRCQAIINFNYDIEYPAYGVGGILVPSSLIRTLKNCLNRDQHQRPSADELLGDNDTFLNPLEIDMDKHFPMSEELLGRILQNVIQKCEALGRVPSEAELLTAWPKGYFTSLRKAEQRVSWTDRLDGRCWAFSTIGNTLLKDSKIDNITEEEIKWKRMAFWIFLSFSSFLFSRYDFGVCRVYHASFSLISFDIVLGGGWATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIE9</accession>
    <name>A0A5N6KIE9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Heat shock protein 70</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_004885</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIE9"/>
    <dbReference type="OrthoDB" id="434160at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24094">
        <property type="entry name" value="ASKHA_NBD_HSP70_ScSse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000171">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000004">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000011">
        <property type="entry name" value="Heat shock protein hsp88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF4">
        <property type="entry name" value="HSC70CB, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="506"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="508"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8303465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="600" mass="66623" checksum="09289512C46FEFEF" modified="2020-04-22" version="1">MSVVGVDFGTLNTVIAVARNRGVDVITNEVSNRATPSLVGFGPKARYLGEPAKTQEISNLKNTVGSLKRLAGRSLKDPDVALEQDYVSAPLVDLNGQVGAEVTYLGKKEKYTATQLVAMYLSKIKQTASVELKLPVSDMVMSVPAWFTDVQRRSLMDAAEIAGLKLLRLMNDTTAAALGYGITKLDLPGPEEKPRRVAFIDIGHSNYTASIVEFRKGELTVKSTAYDRHFGGRDFDKALVEHFAAEFKEKYKIDIKSNPKAMVRVAAAAEKLKKILSANAMAPISIESLMNDIDVSAMLKREELEELVEPLLARAHVPLEQALADAGLQVEDIDIIELVGGCTRVPALKERIQKFFGKSLSFTLNQDEAIARGCAFSCAILSPVFRVRDFAIHDIVNYPIEFTWEKSPDIPDEDTSLTVFNRGGIMPSTKILTFYRKEPFNLEAKYAKPELLPGTMNPWIGRFTVKNVKADSKDDFMVCKLKARLNLHGILNVEQGYYVEDMEVEEPIPEKDGEKDDALDTDDKPKTRKVKKQVRKGDLPIVSGTASLDSATIATASEQENTMNMEDKLVADTEEKKNELETYIYEMRNKIDDQYAEFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIH7</accession>
    <name>A0A5N6KIH7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">40S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_004980</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIH7"/>
    <dbReference type="OrthoDB" id="10258210at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.860.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_uS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005713">
        <property type="entry name" value="Ribosomal_uS19_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003121">
        <property type="entry name" value="PRK04038.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01025">
        <property type="entry name" value="uS19_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8303580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="17571" checksum="F6A5EEB019C8BDF7" modified="2020-04-22" version="1">MADEEYDAQKAAEIKAKRAFRKFSYRGIDLDQLLDLSSDQLRDVVHARARRRFNRGLKRKPMGLIKKLRKAKQEAQPNEKPDLVKTHLRDMIVVPEMIGSVIGIYSGKEFNQVEIKPEMVGHYLAEFSISYRPVKHGRPGIGATHSSRFIPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KII0</accession>
    <name>A0A5N6KII0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KII0"/>
    <dbReference type="OrthoDB" id="3552792at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="133" mass="14654" checksum="CC3F604C508C3557" modified="2020-04-22" version="1">MPAGFPAYPHTRFPDEKPPTLLHPASPKSPKAKPVSYSTSKSYTATSSSPKDSMDTSSTSTPANDTSSLYSTTSTISLLKHPLNNLKAKLSHKDHQKREETKSKSTTSSTPKHWSEKTPRQSLAETYMIMAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KII3</accession>
    <name>A0A5N6KII3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KII3"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="108" mass="12824" checksum="00D55C3C80AAD796" modified="2020-04-22" version="1">MYTRPGRILLATKDEKIPKTDATYDVKPMQRKTLFIWKHSKIYHEYKVEIYPDIQSKIILDSPRLMTCFTCFTYSIYIRRITNILHKKANWFGGQELDLGQEGVLYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KII4</accession>
    <name>A0A5N6KII4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cleavage/polyadenylation specificity factor A subunit N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KII4"/>
    <dbReference type="OrthoDB" id="20774at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="658" mass="74153" checksum="AA59EA5C1B88DE4E" modified="2020-04-22" version="1">MYMHPQYHSELVIAGQRKDGEISLVLIMENEFHLDVPLVYAEGCSYDLRALSSIILKPSSSSDNFTLICGTLTGLVLSLDIVKSEEHFYIRESRSDRFGGSVATLTNGDQLDQSNFLFVNCDEKIFKMDLNVSSTQGKSCKEKAVRMKMKADQIWLLDALDTTLQQPNINSILPLRSESLADIDLLLVSYNRLLLARMGAKRKTVPRRIHIRGTPYRIIYSETRKAFVVGASVEGRSTIYFVDPKTGENLSDPRDGKRGAQTDFVAGLGRFDDKILCIYEWLYSHNAHTWNFLVVCTSDGRVLIICTKNDGSSVTPSGRAKISFWTVTQFKNFTSVYAVTGDSEGLYYCAQSGTEVKLYYSTLNKDVKKFNKNPAEVKLLSPAISLSYDSGKIYALTRHHSLQILEVIKTNGQIQLHHTHTDQLQRESLHHLQGKPNTSGSLGNSQIDLVSDRSRSVTGLCVSSGMKVDTLDTIFEAQLPASVLRLRSANCRPVWDCSWMVHKNGTQVSGDLPARLGVIHNDEINSETLGMGIDGSLYHFTMLDIPAWRFLKFLANLARSSSLVGGCPWEGWTDLEPEQTPRNMQVDGDILKIVVENGKLEELFRIGEHQTDENKREFKRFCDLLNMIHDKELKNDDDPMFYIELAYDDLEVFLRPVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIJ9</accession>
    <name>A0A5N6KIJ9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA repair metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIJ9"/>
    <dbReference type="OrthoDB" id="262529at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16273">
        <property type="entry name" value="SNM1A-1C-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000038">
        <property type="entry name" value="DNA cross-link repair protein pso2/snm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF6">
        <property type="entry name" value="DNA CROSS-LINK REPAIR 1A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="742"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="862" mass="95818" checksum="3199A16F3A259D11" modified="2020-04-22" version="1">MFRNPRENSIRSTDSQLQPSKGRPPTPPSALSIPRKSITMAPRNTNKPTTPQSASKSIASAFSKQPTKKIAISRTPVRANGNIMNFFKKVDNPFKDDDSLFVAQRSGTAVEPPPEIADDDLYGVNDEGYDEAERSIKKRKLSDKTNTEDLSIPTPPLAENQIPIAKGKSSRKAPRRSGPFLDDSDSDAESMEAILTAQAKTQIERKQPENSTIKGIAGLGTKQEHTVEKKSDMISTESILPLGSSVFKLKRRVPIKRAQAEWEAKQARNAKAMSSPDEKPEYRGGSRYFDNWESEKFETESEYDDEKTSNGYKNSDSKPKGKGKRKRKSNSHPETGTLKEENTSTDTWEEFEGMGEFPDEDVDGEEFMERKFMEENNLEADNEAQTEEDSFNGFDDDLGPSTNLEEERISTCPMCDANLSNITSKQVSMHVNACLDGNPIPLPTKTKAKPKVHTESSEAKLMPDDARSRYSKKAAIPRPGQANPIELGNDGGSAFSRIMSGNIEDAAWASAADKEKSSRGKPAYQRTCPFYKIMPGLFICVDAFRYGAVKDCKAYFLSHFHSDHYVGLTSTWSHGPIYCSKITGNLVIQQLKVDAKWVVCIDFDSKVQVPDTKGVSVTMIPANHCPGSSLFLFEKSIGRGSNPKIQRILHCGDFRACPAHIAHPLLMPNVVDSVNGKTKQQKIDICYLDTTYLNPKFAFPSQDDVVKACADMCVSLSKENAEEDDAWETVKRERAGAKMTKFIKSASKTETEDSNTTEAPSKDKKKARGRLLVVCGTYSIGKERIVLGIARALDCKIYAIPSKMRICAALEDPELTSRLTSDPLEAQIHMQMIMDLRPETLQDYLSVYKIHHGRLGATERKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKH3</accession>
    <name>A0A5N6KKH3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8304091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKH3"/>
    <dbReference type="OrthoDB" id="4966at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="84" mass="9605" checksum="A59C429D6621F3EE" modified="2020-04-22" version="1">MVFNTTMGRRSFFGLNATSCYYFLGLYWIIGYSRFVTLNPKKCKLKGQLNWHAFCLYVLSDEDSYQISQISSSASADSLPHLCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKM1</accession>
    <name>A0A5N6KKM1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_005131</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKM1"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000473">
        <property type="entry name" value="Vacuolar sorting-associated 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF220">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="8">
        <location>
            <begin position="31"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="7">
        <location>
            <begin position="609"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="536"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00073589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8303749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="696" mass="76913" checksum="1355AE97E264A6D8" modified="2020-04-22" version="1">MAAQGGISDPGLITLVNKLQDVFTTVGVQNPIDLPQIVVVGSQSSGKSSVLENIVGRDFLPRGTGIVTRRPLVLQLINRPPAAKTNGVKDTEELISGGDKEANADEWGEFLHIPGQKFHDFNKIRDEIVKETEAKTGRNAGISPAPINLRIYSPNVLTLTLVDLPGLTKVPVGDQPRDIERQIKDMVLKQISKPNAIILAVTGANTDLANSDGLKLAREVDPEGQRTIGVLTKVDLMDDGTDVVDILAGRIIPLRLGYVPVVNRGQRDIDNKKAITAALENEKNFFENHRAYKNKSTYCGTPYLARKLNLILMMHIKQTLPDIKARIQASLQKYTTELAGLGDSILGNSANIVLNIITEFTNEWRTVLEGNNQELSSVELSGGARISFVFHELYSNGVKAVDPFDQVKDVDIRTILYNSSGSSPALFVGTTAFELIVKQQIKRLEEPSLKCASLVYDELVRILTQLLAKPLFRRYPQLKEKFHAVVIAFFKKAMDPANKLVKDLVAMEACYINTGHPDFLNGHRAMAIVNEKHNASRPVQVDPKSGRPIPSTPARTASPTLEGVSDGQNGGFFGSFFASKNKKKMAAMEAPPPILKASGTLSEREGTEVEIIKLLINSYYGIVKRTMIDMVPKAIMLNLVQYTKDEMQRELLENMYRTDTLDDLLKESDYTVRRRKECQQMVESLSKASEIVSQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KL04</accession>
    <name>A0A5N6KL04_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KL04"/>
    <dbReference type="OrthoDB" id="2283785at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039634">
        <property type="entry name" value="Bul1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904:SF1">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="1">
        <location>
            <begin position="29"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="291" mass="31540" checksum="89BF5966D94D15B0" modified="2020-04-22" version="1">MSASSVHSGSGTIANYAKKINPTKRPDVEIHIDDHHEGKTYTTFDALSGRALITAPHDAPFDEIQITLEGVTRTYVENISHSSATSKTTAVHRFLKLIMPIPETAYPQPRIAAAGKTYIFPFNFVIPEQLLPTACTHPSDADHVHTAHVQLPSSMGDRELSILDDLAPEMSKIQYSINAKVVKYTEFPKKSTSLVGGSKKLQIIPMVAEAPPMSISEDDKGDYLLSKTKSLRKGMFSGKLGKITVLADQTAAIVLPPPGSSSVATTMATVKLQFEPRDINSQPPRLGGLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KL08</accession>
    <name>A0A5N6KL08_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pirin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_003781</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KL08"/>
    <dbReference type="OrthoDB" id="198735at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024788624" description="Pirin" evidence="3">
        <location>
            <begin position="21"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin N-terminal" evidence="4">
        <location>
            <begin position="77"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="5">
        <location>
            <begin position="220"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8304375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="38438" checksum="D01B14C52FEE3C8D" modified="2020-04-22" version="1">MKLLLLLFSITIAIFSIIFQDSIIQQIEIITNLFTNDTSTIPLLKPFPKFHPTAYFGTSKAVNMTTPRGIQKAFFGTNFSPFLMLDHFTIKPGAGFPDHPHRGQETITYLLEGAVDHEDFAGNAGTIEAGDLQFMTAGKGIMHAEMPRQNPDGSANVGMQLWVDLPEKLKKCEPRYRDLRAKEIPQIDVDDGKVHVKIISGQSHGVDSVQELAYTPVWIFDIEIKPGGKIEQSLPAGWNAFAYTLSGETVFGSGEEKTKIAQFHNAVFRQEGDLVNAEVEESAKENGHFILVAGQPLDQKVVQYGPFVLNTEEEVYQAMMDFQTQSNGFERAKGWRSEIGKTMVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMP1</accession>
    <name>A0A5N6KMP1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMP1"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF4">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="51"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="225" mass="24598" checksum="6FE566A71E1E3962" modified="2020-04-22" version="1">MGVTTSTSTISTISAATFKPKQTKLSISDTSVESFPFLEEPLLRLPETIGILIEVRTSPKGGLGVFALCPIPPNTLLLSEQPLVILTDTGTRIDPLDALVSALSPSRKNAFLSLHAYRANPRETRNRSILYSNGFGVGKVESLSTGVFETASRFNHACVPNAGYRWEEEVEENGENGELGGRMKYFSRRDIGLGEEITVDYGHGLKGLKKFYGFECDCGKCRLET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMP9</accession>
    <name>A0A5N6KMP9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMP9"/>
    <dbReference type="OrthoDB" id="3546685at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="573" mass="62897" checksum="1B942D25B6D5EF6B" modified="2020-04-22" version="1">MQQQQGLERDFGTAYGFSGHSPSPPNSPSRGKQRRARSPRNSVNQSSIPIPVSGGYSSEAEAGTGSASLKDSVRFSDVQWSSVGSGGSATGTTVTMESGGNGDSLRGKGTGAGAGAGKHKAAPGQRRLRRKQNFEERDQSPAATPASSRSQTVSKEDEILRREEKGKELRKESREEATTMEQLEMMRVAMWNGKLEKVVPPSKSVPKHSDILQPSTPASTSGRNSRNKGKGRVMEGRASPIQKLKGYMGYGVEVVDDFFEKKTNLKTGGKLPSPFEYLLYPSYEGKGKGKGKEEKGIVESRVKAKSKGKGKGDKGKDSDDELWGCVGEQNNESGILATPPTKENRAMVKEANFQKTKKESSTQWENRCKLCRGHASSGPRGLCRTCEDNFLNTKAWEDTVENFSDNSDIPPTPPLKDRHITSMREVLATTPPNYHAESSSCPPAQAKDSIHVLRVENSRPQLVNPSPVRQESQKLIYGGMGDSPRDIEIGFPEWQAHLLEVEGTKTEQMFKRWSDNYRVDDSTGGVDGDGEKDQEKEQSPRHSTFYDFWGEILMEDGRSETPKSEDRKPQTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMQ3</accession>
    <name>A0A5N6KMQ3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_004392</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMQ3"/>
    <dbReference type="OrthoDB" id="3045089at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06503">
        <property type="entry name" value="ATP-synt_Fo_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054464">
        <property type="entry name" value="ULD_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF66">
        <property type="entry name" value="CARD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22893">
        <property type="entry name" value="ULD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="622"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="603"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="706"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="342"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="710"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8305093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="822" mass="88559" checksum="F2B5F3CD888CECB2" modified="2020-04-22" version="1">MPLRTRGPTTRITIDSPNTQSPYTTPSHSTSNSRSNSFSEGSSGHLRSDDSHEFSDNSQDSWNGLDYSEDIEPSESGSRPRAATRYIGREQISSREQSTSRPPPVERAHVSYERPVRRHTPAAERNHRPPISRVHRHTAPAPLSTVEQSDDFSGYSRGYAAQPTAPYGGGRTAPPPSYAPSAYSAGSNGTPYPPPFGNPGIAPPPGPGPGALTHYGGGYAQQYNQGSNPFAPQNPNSFAPQPSPSPGGASYFNSHSRHDPMARHDPMARHDPMARHDPMARHDPIQWLDTIQWLGIIRLADILVMAIKNLCITRLLNTVTQEINLMVEIKATQDTKGICLLMKNAKIESDRAKEQAEAAQRASEAAQKALADKEARELKEKLDAEEAAAAAQKLADERAEWARKASEAQAAIEKRAAEKQAELEKRAADMEADLKKKAADAEADLKKRMEEAQTLLAAKLALEAKAEKEAADAAAQAALKAEWEKKAAEAQADLLKRAATMEADLKKAAADNEADLKKKMEEAQSALATKLAKEAKDAADAAEAAQAAAIKAEWEAKIEAEKELALKKGAADALKAKEEEARAKAAEEEEAKKKADEIAAAVAAATAAATPAPPPPPPPEEKKKPIKFKDAVGRKFSFPFELCATWPGMEELIKQAFLHVNVIGPHVQNGHYDLIGPNGDIILPQIWDTVIEPDWAITMHMWPIPEPKKPAPPAGPPGPPPMNPNGPPNGARPPPPPGVLPPPPGVGPPPPPPPPGFAGPPPPPPFMSQGPGPRIVTAKNPRHHQKAGQKSELYNNLHFMWTPQYITNLSTYTCHDVAMSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMQ6</accession>
    <name>A0A5N6KMQ6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3'-5' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_004291</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMQ6"/>
    <dbReference type="OrthoDB" id="1920326at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06141">
        <property type="entry name" value="WRN_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000100">
        <property type="entry name" value="3'-5' exonuclease/helicase (Wrn), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF104">
        <property type="entry name" value="EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="4">
        <location>
            <begin position="185"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="380"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="464"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="392"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="471"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8304978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="613" mass="68194" checksum="5F10527C7A7016F9" modified="2020-04-22" version="1">MKNISSFIGKSHFAAIEGMGSAIAGMSGKRASPSLTRSISSNSPKTWQPSYGIVFKDVSAPGSSRVLSTTAVADNEQNFAFHSYAEESYVLTNSHVESSKTQMATTVAPEDISKSEEAADVQEIVGEMQQDQEKNEPPVSDSTYQMSGELFRKAKEALPETPGSFWSHTLYRGPEENGIPKKVKVHYCRTLQTTERTLQQYFVGHKVLGFDIEWKADARTTDPAKKNVSLIQLATEERVGLFHIALYPTNDVSRLVAPTMKQIMEDPEVTKVGVAISADCTRLRKYLEIDSVSIFELSHLHRLVKYTLSQEHDQINKKLVSLAKQVEEHLHLPLYKGGNVRSSDWSRELSIRQISYAASDSYAGYHLYDILETKRQALDPMPPRPCHADENQPISKPTSSVPTSNPTKRKYTRRKPTVDALRLDSGFSIGDPQPTLEVPLDALNETETETETKVIALTPNIETPTKTERVPTTCSTSDPGSSSSLETPIKKERVRVRGTSSTSDPESSSILIAADILVAFHFNANPDSQIKRSGLKAYFIWYHNPHLSLSQIATLLSEKKTAFEAAKIILNAIDTGDLPYDRKRLRALTEILPEYVAWSNYRGLLEAIDTPNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMQ9</accession>
    <name>A0A5N6KMQ9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMQ9"/>
    <dbReference type="OrthoDB" id="1594986at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031106">
        <property type="term" value="P:septin ring organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000176">
        <property type="entry name" value="Rho guanyl nucleotide exchange factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053026">
        <property type="entry name" value="CDC42_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339:SF1">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PB1" evidence="2">
        <location>
            <begin position="379"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="477" mass="51786" checksum="93820CE63DA95F55" modified="2020-04-22" version="1">MKKWYEGVDRQKKEHANTGAQASTSPDTVARDFEWTREQTASMPNPYAQQDEEEEEEDYSGTTAYGSPPNSGMPPNFGLPPNASMARNSSSTSLRSRSATAESNQSLAGIARAPPPRFPVGMSMTPPLSVQTQMSVPLPSPSQRLGDSYFSPIGESPASSARTSTASSGMYQFPRQPTPQGSWEDSNRYTAPAIGRVPSRDSQNSVNGASYQMNGRTPQRPSLPAMASQSQAAAAQQRSRSYSTPDINAQQGVRRLPNGALSTPQGQVPAVPGIPAHLHPAYDAGVPRSQNNSPNGLPVRTNTQSPGVQRERLQQQQQQSQYPNGSQNLGVSQPNYPRSNTTQMPTTALDSRLPPSLMTGNAGMSLSPEGDMSLPTQLKVKVNCDGNYVTLVVAFNITYQSLTDRIDAKVGRFSTNAIARGTMRLRYRDEDGDFVTIESDDDIQIAFQEWSEAQKSQYHSGQLGEIELFCLSIDGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMR9</accession>
    <name>A0A5N6KMR9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Anaphase-promoting complex subunit 4 WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_004304</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMR9"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF8">
        <property type="entry name" value="FI02843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8304995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="37139" checksum="6ED7DDDF57125487" modified="2020-04-22" version="1">MATAVSTPIKSHAGLFSTRTAGGRMPLTPSPRTRTQTLSINNSSPFTPPERKVSEENVRLSSKSTYGGNLTSHFAKSSRKSHRDSPKSNIAKGVQTPRHALELGVSDFALTGTGCKTPVSGRTRKGPIRSKSTKTTVSYSGDRFIPDRAASSAITTAGCGKADFAEKQRPKSINESSAVLASGATDALAALESLNLDDEEEPASYSRPSPNTIAYQDSLASACGISQGQRILAFKPAAPESSKPVDLRSQYNRPLKNHNATAAQFRRRIATAPERVLDAPGLVDDYYLNLLDWSSNNQVAIGLERNVYVWSAESGTVSSLLETSPDTYVSSVKWSGDGAYVSKHART</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMS2</accession>
    <name>A0A5N6KMS2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Protein transport protein Sec61 subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_004244</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC61-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMS2"/>
    <dbReference type="OrthoDB" id="5401193at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005784">
        <property type="term" value="C:Sec61 translocon complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030671">
        <property type="entry name" value="Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016482">
        <property type="entry name" value="SecG/Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13509">
        <property type="entry name" value="SEC61 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03911">
        <property type="entry name" value="Sec61_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="108"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8304921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="25282" checksum="98DDD83F64639A3B" modified="2020-04-22" version="1">MEINNVLSANLSFDNLDWWTSSSKANFTSSLRLLLISVLSIQFETYFKDFLLNLFVFEDRKKERKKEGIRNNYEPRSLHSLHSSHRTTFQSFHAVHTIPSNHQIHLHRTNSVTNPPSCLKQSSPRSASPANSPSAAASGRPSSPTPPGGPKTAIRRRAAADQKDKVANARPSSTRAAGAGGSSSTMLRLYTDESPGLKVDPVVVLVLSLVFIFSVVALHIIAKVTRKFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KN13</accession>
    <name>A0A5N6KN13_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004392</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KN13"/>
    <dbReference type="OrthoDB" id="3045089at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06503">
        <property type="entry name" value="ATP-synt_Fo_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054464">
        <property type="entry name" value="ULD_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF66">
        <property type="entry name" value="CARD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22893">
        <property type="entry name" value="ULD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="676"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="760"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="764"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8305095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="876" mass="94465" checksum="2E48ABBD4E6BB200" modified="2020-04-22" version="1">MPLRTRGPTTRITIDSPNTQSPYTTPSHSTSNSRSNSFSEGSSGHLRSDDSHEFSDNSQDSWNGLDYSEDIEPSESGSRPRAATRYIGREQISSREQSTSRPPPVERAHVSYERPVRRHTPAAERNHRPPISRVHRHTAPAPLSTVEQSDDFSGYSRGYAAQPTAPYGGGRTAPPPSYAPSAYSAGSNGTPYPPPFGNPGIAPPPGPGPGALTHYGGGYAQQYNQGSNPFAPQNPNSFAPQPSPSPGGASYFNSHSRHDPMARHDPMARHDPMARHDPMARHDPIQWLDTIQWLGIIRLADILVMAIKNLCITRLLNTVTQEINLMVEIKATQDTKGICLLHGHHGQQSMAMTPPGMQYFPSQFSPPAPEPAPAPTPVPVVDIELEKKMVLMEEQMKNAKIESDRAKEQAEAAQRASEAAQKALADKEARELKEKLDAEEAAAAAQKLADERAEWARKASEAQAAIEKRAAEKQAELEKRAADMEADLKKKAADAEADLKKRMEEAQTLLAAKLALEAKAEKEAADAAAQAALKAEWEKKAAEAQADLLKRAATMEADLKKAAADNEADLKKKMEEAQSALATKLAKEAKDAADAAEAAQAAAIKAEWEAKIEAEKELALKKGAADALKAKEEEARAKAAEEEEAKKKADEIAAAVAAATAAATPAPPPPPPPEEKKKPIKFKDAVGRKFSFPFELCATWPGMEELIKQAFLHVNVIGPHVQNGHYDLIGPNGDIILPQIWDTVIEPDWAITMHMWPIPEPKKPAPPAGPPGPPPMNPNGPPNGARPPPPPGVLPPPPGVGPPPPPPPPGFAGPPPPPPFMSQGPGPRIVTAKNPRHHQKAGQKSELYNNLHFMWTPQYITNLSTYTCHDVAMSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KN14</accession>
    <name>A0A5N6KN14_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KN14"/>
    <dbReference type="OrthoDB" id="310217at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053235">
        <property type="entry name" value="Ser_Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361">
        <property type="entry name" value="MITOGEN-ACTIVATED KINASE KINASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361:SF824">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="450" mass="52992" checksum="5363637159783DB5" modified="2020-04-22" version="1">MGSDHSPTLTLSSEAQIMEEEEMLRKSLYAKRTNEMKTSIRYIREGHPNVCNMEGFGEFDILGNHYFMYVLELCDLGTIMDMVHQFRDMAEYIPEGFMVSFIKFSILYSLFCVDMANLKSQWHAFEQLLDGLTFLHGEHPDYQDNERSRGKDCAVILRDIKPNNVFLQSSHEKDTYPTVKLADFGEAIHLPIGGTRNFVFGNTVCDPPDNKMSAKYDVWSVGAEIYYMALNGAYPDKGCEMSNLKWPLYGDASPAMKKKMTDLRNNPERFKKIDNHLTLELYQTLRWVMNLDRHERPRAREAWRRVKEKNAQRKKLMYRPLPDWVKMIVDKDFAPLELVQLDFKIQQAEAEGFIFEYAGNIPRTRKKSERQYILESLEKEKGNSQAMKDEKLRNFHLRAGERRRAWILEGRKRETEVEEIGKIEEERERLRGWLEPTIKKRRMGLRKLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KN43</accession>
    <name>A0A5N6KN43_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Something about silencing protein 4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KN43"/>
    <dbReference type="OrthoDB" id="1938992at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033255">
        <property type="term" value="C:SAS acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038988">
        <property type="entry name" value="Sas4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029184">
        <property type="entry name" value="Sas4_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38422">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38422:SF1">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15460">
        <property type="entry name" value="SAS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Something about silencing protein 4" evidence="2">
        <location>
            <begin position="269"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8305041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="516" mass="58438" checksum="C07B74059A8175E9" modified="2020-04-22" version="1">MSSNTRSLRKSEALTTSSGNPVAMSPPNVNHNFGAHTQSNMNGRKRTRESADSDDHLLPKKKTKLAIEIPPPKLKSLPPRKRSGVIKSNANPDNTSATSVQQLQRATPADVRTTHSPSHHHHHHHHQQQQQQQQQQQKPKRHHHKVANGLQHELEGLHDRLQVKSDLKDERRKLRSQEGTKFKSELSAYFPEYDEIIGNVPKEEQVIDADTPIVMIDSSKVSSENSRTPKQEQDCEYAVKDYPSSLFTNLHGTSRVDFSAFTPVACDGDPLSEEHFKTLHKRPERQEKAVRNADKSRAQHERDSVIRLMEGLQGPDWLKTLGVSGITEGRKKEFDSARQYFIKGCESILEKFRIWKDDEKQRKLKKERALAEAQARAEAESEDDEDLESDLESNGDPPDLSISDIDASAARQLHDEAIASSTPRRGARTNSVVTTAPPAPPVDSEFKSFFAKPYLRDAALGKHRRSGRSVAAWGHPVPDLPLEGEVDFDLPEEYRDVETLRAHARRKRRDRRLIRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JPT2</accession>
    <name>A0A5N6JPT2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_010106</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IFI6/IFI27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000031">
        <property type="protein sequence ID" value="KAB8287402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JPT2"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009311">
        <property type="entry name" value="IFI6/IFI27-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038213">
        <property type="entry name" value="IFI6/IFI27-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16932">
        <property type="entry name" value="INTERFERON ALPHA-INDUCIBLE PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16932:SF18">
        <property type="entry name" value="INTERFERON, ALPHA-INDUCIBLE PROTEIN 27-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06140">
        <property type="entry name" value="Ifi-6-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8287402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="123" mass="12450" checksum="5F7A9094C0AA76A5" modified="2020-04-22" version="1">MLSFRKKALGGPVTIASIAVVPILGAVGFSAVGPVARSAAAAWQSSIGLVEAGSFFALCQSIAMGGAAIGGIVGAGLGGAGILAVATSLNELDGVDFDTFELKKRFQEAWKREIRGDQRTQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JQ94</accession>
    <name>A0A5N6JQ94_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_010528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000021">
        <property type="protein sequence ID" value="KAB8289613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JQ94"/>
    <dbReference type="OrthoDB" id="5418203at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8289613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="138" mass="15662" checksum="78741A076833D714" modified="2020-04-22" version="1">MTTDPDEITTTLQTLSINPSSTSKSKPTSTSTSPHPQNPSPPNPHPPSPTPGKTKQAPPQRPKPQPQTLPQTSPKTDAVARRLIAGALGIRAPKKSDEQREYERVQREKESRRRQEEREESERRRQEEERVKRGVWED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JRV9</accession>
    <name>A0A5N6JRV9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="24">Dicer-like protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">EYC80_011111</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the helicase family. Dicer subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000018">
        <property type="protein sequence ID" value="KAB8290244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="416741at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050688">
        <property type="term" value="P:regulation of defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd18802">
        <property type="entry name" value="SF2_C_dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1520.10:FF:000015">
        <property type="entry name" value="Dicer-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1520.10:FF:000032">
        <property type="entry name" value="Dicer-like protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF37">
        <property type="entry name" value="ENDORIBONUCLEASE DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51327">
        <property type="entry name" value="DICER_DSRBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="3" id="KW-0930">Antiviral protein</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="11 15" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="19">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="20">
        <location>
            <begin position="323"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Dicer dsRNA-binding fold" evidence="21">
        <location>
            <begin position="517"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="18">
        <location>
            <begin position="871"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="18">
        <location>
            <begin position="1053"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="17">
        <location>
            <begin position="1300"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1338"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1338"/>
            <end position="1348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAB8290244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="24">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1361" mass="153876" checksum="E3F3EA51CC89B88A" modified="2020-04-22" version="1">MKSIVRAVLRILVELERMEPDKVIWFLAPTVALCIQQSDYFQLNFPSILTKLLVGANGVDRWAEQRQWDAILKDVKIVVSSYQVLLDALTHGFVRIERLSLMIFDEAHNCLNKAPGAKIMTSFYHPNRSKTSLPHILGLSASPVMRSDEKSLNKIEETLDAICRTPKVHQADLRLQVKLPILSIIDYIPEAECIATRSIASLGMVIQGLNIFEDPCVLNLKRSGSEKSQRELEKILRNHKTYSQVQLRSIYDTSHGIILPELGSWAADYYITAVVTKYLKAIMITDDSAVLDTADAEKFYIAKALKKVETSPSLSITGRVSNKVAKLIEIIGQQDRPFSAIIFVKERATVSILAHLLSQHPHTKERFKIGTMVGTSSHGNRTQSIKDIVDSSEQKDTLSDFKRGEIDILIATSVLEEGIDVQACNLVICFSKPANLKSFIQRRGRARQHDSKLILLDALGDKVIDWHELERNMRKIYEDDMRDLQHIFEIEAADEKLEDGRFLLIESTGARLDLDNAVPHLHHFCAVLTVKEFVDSRPDFVYSSDLGSKYVQARVFLPLSVPETLRVHKSRGSWLSEKGAAKDAAFEAYVALYKGGLVNDNLLPLMVHNEVIDELTSKPVDTRASLLQVKERLDPWLEITRAWEEAENNPNIVRTSIMSFDDLEIELCLPIELPVIPPLKLYWDFKTEFSVDFTNDTKTGTSKALISQALNDTYLLLSGAFSRKFPIWSRRMVVQFIVHRASSSLNLDCFPVRLDGTFQNTGFIRKSENLAQPYILEKWLLRKPPINEVRHPDLDYLHTPIDAPHLALTLVSRRTDFLHKVKNEISSTSSKQFSYVLPASACVQDAMPSQLLQLGMMIPSITHHIEIQLVVDRLSRTILKTLEISDPRVVQTAITASTYSGILNYQSLEFLGDSILKLCTSVQLMAEYPLWPEGYLSAMKDRIVSNSRLSRAAVELGLDEYIITRSFTGRKWRPIYVDNYPETTEQKTREMSSKTLADVVEALIGACMVDGGIPKALKSLQLFLPEIHWLPLETRRSSLHRRAPDDLGSPITLQPVEKILAYTFTKKSLLIEAMTHPSYSIGTQSLERLEFLGDAILDNIVVTAMWSHELELTHFQMHLLRSALVNADFLAFLCMEMSIEQDIANLIEGPDHKIHEVHTSRRVPLVNFLRHSSIPVSLYQKQALSRHLELREQILAVIDTGDKFPWALLSRLDARKFISDMIESLLGAIWIDSGSMEVCTRVMERMGVLKYMRRILKDGVRIMHPKEELGIVAGNDKVKYVLRNKKIGDGDEHKQEGGLEYMCKVFVGGKEIVDVGGGVRKEEIQATAAEKAMEILKARDRDTAKDEQTEVAGGTDKMDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JS82</accession>
    <name>A0A5N6JS82_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1941 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006534</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JS82"/>
    <dbReference type="OrthoDB" id="8962942at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008709">
        <property type="entry name" value="Neurochondrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109:SF7">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05536">
        <property type="entry name" value="Neurochondrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8291739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="536" mass="59428" checksum="6AC0A8F581129AAA" modified="2020-04-22" version="1">MVKALVQSSPETTQLILQTLLTIVSQVEGSLELLKIQDLSPLTEIAPQCPLVLDILNYTWANGSTVNTEVQTVQGSINEVIPNLLLVFKGTDAVTFLSFIASFIPKLTLEALPRSPKWLRSTIILLRALVNRRPTLAGRVAYTQAAAALLQAYPATCPSLLFNDESLNTSDKSERNSKPFSYLFVNLLLIDLRSSFPSLLAKLNNSDYSNISQRLAAAFDVISSFIGHLVRSLDDEDFNAFTISPDLMLKLRKDIAETMSLSIEYLRDRWDASIAGASGLHPSARAGTTATSEGTRLTLTWDSMKDSVTADPLVLASIRGLAIWIREDENENLRKETAGMMDMFIELYKISFKEEPDFRYPILLALEGIMTTEDGVEAFLNQDGWQIVSEDLASILTKANDTLNIQNHSLLISEATRGLQIVRILLAVIDEESTSHIKHEWLTTVSFTSSMRFLTSRLPSAVVELHIAMLQLSTALLSKSGEGIQKRHSDDQKALTKLVGQLEAKVKDMEDKQEANEFLELLADVVLDLENLGRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JTZ7</accession>
    <name>A0A5N6JTZ7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_008252</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JTZ7"/>
    <dbReference type="OrthoDB" id="2162761at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="212"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="136"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="160"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8292542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="841" mass="95918" checksum="DAA904FCFA259B7A" modified="2020-04-22" version="1">MRKPSAYLTALELIGGGGLSSESPCLRRQATTCALDDINEYRLSQYNVKKHSSAVLQAFAISIFHQSNNRFVYGATVRSSVEPQGAARPIVIIILDQQPVFSISFLTIFHSPLIFLSRASFHFEIGAIQNTRNDTSLTFTMSGPPNLRTLLPNKTDTTLRDSSTSTSNNKKITPDTTSSAPSTSSVPTDKRSEKSSHIIKKRRVPSSITTNACGNCKKARSKCDGKQPCGRCVSKGFRREVCIYEPHTKNAKRTLVRDLKESHRIKHSAERIFECLASNTENEHEILERIRNKESIKSIAEWLDSIDSNGESQLSIYAGSDHEIIRDQLKDVSWTTVTHDQDIIHHLMTLYFTWVHPFHPLFNEGHFVESMRTGSKTFCSHSLFNAICAMGCYLHTSIENENENENENENESGDADYKQMGIQFCDLVRSVIDSEDRNLTTIQAFAVMFLIRCAQGQGLNGSIYLAVASRSMESLRPSNNDDVNYRQIWRETVKGINSLNVEWAQMTFKMAPAFIPELQPTQYSEEVTRWEEQVDRLRWKQYRFPLDLKGEPTFSCLTATTNREKSKLIEIIHDITILLYDKTGSRIYAEDMLAIYRRLLVWRENLPENIANKGKKDAQMLPHVLSLHILYATTAVQLLRPMMDLGEPSIEKLVWSHAQDGLNLIDDRYRFQYTCRYQPVSQIFALLHLTEVMIRYFPGIDKEIGKDGVASIKLATDILRESHSSFPVAGISMTMLQETARKLLVPLPNQLEDLFRRRRRKSRFLLDDAINACANPTYLQPVETIRKRFSPDLPSKWMIHGSFGYPRIPHALSISRQPPQLSEEERGARDLLRILNLRNTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWA0</accession>
    <name>A0A5N6JWA0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_007548</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2420415at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000122">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025305">
        <property type="entry name" value="UCH_repeat_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13446">
        <property type="entry name" value="RPT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="621"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="727"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1096"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="727"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="767"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8293208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1345" mass="152841" checksum="9AAED989962F07FD" modified="2020-04-22" version="1">MFDYQKNPGPGKSAPRLLNDLLDYDLRTSAKTGRHILIDPAPIFNGTYVDQGSYCRHHLCIKDSQTSNLRPHEEPDRTTIYKTAAYCSQCRYHFLITVDFRDWEDGQTLCNFKDPENPLHHFRVLDSKLSKDSKDAYKLVVHQFACTSVTCPVKVEIKVQSPRLSTSMVSLLINRQDILVRGQKEIESDPTRFEGHRPLYPIQVLSNLRTYLQDAGGETRKQIARRNKKFRLAFGNDCDSLLSYLGFELKLGQSSQSEEEFAQYWTLPAVDDKNREFIDDVKFELYQLMLERPDEEKKLPGVPRLSYIAVAMPEIRQYLACKDYPKRDRDAVQVVDAVEHPHYASLGAMERFTDDLLAWSYDRQCQCDPKNKPYYLDCLREIGNGRRSSDLQMKATMILSTGEASLKDIEKAYSFFALRRSDTKDEADDYIIGVYKSRVDSAPRQKEEARDCLLVIAKDRQSIAIEAVANDRTMSFEEALEFLNVSSDTASDSIEAAAVAMSFEGDKNKVAKALRAIANQRGDDYTLQRAATSMESGTEASNLDVGEAYNRLQINDRTAPDDTVLAYYESLRTGAPTGSSDSYTEAFRVIAHDRQSSYLLRKLDDPNADIQAAKSTVDQPVGLDNIGNTCYLNSLLQYYYTVKSVREVVMNFEQNRMPLDEEGINKKRVGGRAVSKAEIIKAQKFATELHDLFENLKTAPTRSIKPTRELAELTIFSSAAEANFRRASISSPSAPPNIASLMSPVFGPEDPPTVNSPPLSTDDDIEMVDRPEDKDPSQRDDSSEGTLVDAPDIDGLPPYSDVLRKTSDAAEKVWDTKTEETSSTFDDAIMVNGDSVFPASDIIPAAPDQPPPVPPRNKGGLSIQTKDHKEVITDDDLWKFGSQQDVTEVIGNVMFRLQCAIKPTSIDPVSGEQIDNIRDTFYGANASYLRKSQKLEKKVEPWANLIIFPDENKSRDIYEALDVVFDEQQVHIDGTVQPQYASITKLPPILQVQIQRTRYDNIKHTAYKNRNAVVFPETIYLDRYMDSEDPDSPLMRRRQEAWKWKTRINTLEERQKSLGQEKAAEEVSVCDALSAAHSLTKGLQEMDDIEVDAELVALLDERLVELNQEIERNNEEIQLLKQKRNEQFTNMTKYEYKLQTVFIHRGEAGGGHYWIYIYDFENDTWREYNDEYVTEVRDRRRIFEHEAAGVSGTPYYLGYVRSADVTDLVGAVHRELRDVEMPSLPPVTGTNSWAKTLEDGVEVHHNEDVEMEMGEVKRAEHVNQRHIMPKTDGDRTGVISQLINWNGGEGHVMESSYSEHDIRCERAQLVLLIFGFKHCVHMDHGNTCVFITSGWEQGRERCLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWD1</accession>
    <name>A0A5N6JWD1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_007563</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWD1"/>
    <dbReference type="OrthoDB" id="10262653at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1740.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.20">
        <property type="entry name" value="Ribosomal protein S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_eS26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047864">
        <property type="entry name" value="Ribosomal_eS26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_eS26_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00733">
        <property type="entry name" value="RIBOSOMAL_S26E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8293225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="91" mass="10396" checksum="73FFF5B533C0D69C" modified="2020-04-22" version="1">MVKKRASNGRNKKGRGHVKPIRCSNCSRCTPKDKAIKRFTIRNMVESAAIRDISEASVFSEYTVPKMYLKLQYCVSCAIHGKIVRYVNAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWD2</accession>
    <name>A0A5N6JWD2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWD2"/>
    <dbReference type="OrthoDB" id="43460at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="251" mass="27807" checksum="255E4BB30F8FA3DB" modified="2020-04-22" version="1">MKTSISLQVTAGFLHKYTQHSISIPTVLLLSRRNHNGGDLIGSLGRIDSFALLRRNYSKIHLDFFRVKGLNNTNKCTSLLPPNYALRRSSATTTTTTTTTTTTTTHTCNRILSSLSPNHPKKRNTARETSLPTPVQSSLGNWATVLLLTFISSAFLYTSTKGQPKTQGPESQQAEQVDFEQEYYEYYKMTGEALPGRPGTLTAHEEEKLREFWVATLQVFGVLDPQADANGTNGDSEVSNEKEVLCSAQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JWD8</accession>
    <name>A0A5N6JWD8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Endo-polygalacturonase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">EYC80_007588</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in maceration and soft-rotting of plant tissue. Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JWD8"/>
    <dbReference type="OrthoDB" id="1546079at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050434">
        <property type="entry name" value="Glycosyl_hydrlase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884:SF9">
        <property type="entry name" value="ENDOPOLYGALACTURONASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024965567" description="Endo-polygalacturonase" evidence="13">
        <location>
            <begin position="21"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAB8293257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="26940" checksum="393177C2933272B3" modified="2020-04-22" version="1">MHKTSQISGLLALTLAGVCASQTPCIATKYSEIAPCVGSSTDIILKDVYAPSNSAIDLRKLKAGTTVTFAGKTTFGFTNDSSFEPILIGGSGITITGEPDAIIDGNGQVYWDGLGSNGGVPKPNHFIAASKLTGGSVIKNLFIQNWPVHLFTIRDADGLILENLTLNNTEGDAPNAASGKLAAAHNSDGIDLINSNNTIVRNISVWNQDDCVAITSGNNVTVDGLYCFGGHGLSIGSVGGKAYNNVTNIVVCFIHSIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYC2</accession>
    <name>A0A5N6JYC2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xrn1 helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_009602</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYC2"/>
    <dbReference type="OrthoDB" id="28245at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1050:FF:000002">
        <property type="entry name" value="5'-3' exoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF41">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xrn1 helical" evidence="7">
        <location>
            <begin position="3"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="271"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="297"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="321"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="381"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8294162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="405" mass="45156" checksum="0A8A9F7371D1B7BB" modified="2020-04-22" version="1">MTAKFNRDPKDIEFRHQVGRAYVEGLAWVLLYYFQGCPSWDWYYPYHYAPFAADFANLKDMKISFQKGRIFRPFEQLMGVLPAASRQAIPEQFHHLMTNEDSEIIDFYPEDFIVDLNGKKFAWQGVALLPFIDSERLLDAMAKIYPSLPADVSARNGLGRDVLLVSEAHHALYDEITSKFYSKKQDSPHMKLNPKVSEGLTGRIEKNEDYLPYSSLAFPLDSGAMPSLDEDRSIRVHYEMPKSNHIHKSMLLVGVDFGQPALNQSDIEMTKSRAARSGRNYGGVPLQGDGRGRNQFNYGSGNNNRGNGNRYNGPGTTAPRYNNQSYGSQNNYNNYSKPPPPPGWQPPPPGVGAFARGPPPPPSGSYGGYPPPPPPPPPPGYGSGQGSNNGYGGNYNNYNNYGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYC5</accession>
    <name>A0A5N6JYC5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYC5"/>
    <dbReference type="OrthoDB" id="73788at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8294097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="72" mass="7968" checksum="348EEC1684CF92D0" modified="2020-04-22" version="1">MDLAYDHIQEEALQPDQNKEKTAQPAPTLNADFQEAYKAISSSPWGAKLGGFFGSVVKQVRDGKACQIHEFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYD3</accession>
    <name>A0A5N6JYD3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_009481</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYD3"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF238">
        <property type="entry name" value="MYB-LIKE TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="73"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="73"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8294020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="18873" checksum="9B33054B82A6CAC1" modified="2020-04-22" version="1">MSALLTTFKRSQVPENSEIPSPASARNKRRATGPATASNTSAFNMQSSSSMAGPSSSGLDDPNMPSSMAPPAKKSRTNTPWTPAEEQRLKNMRDAGNSWADIAKTFPARTEGSVKKHWYKDMHYAEFAEDESQALLAAIKDYEVNKWKAIGQKVGKPAKACEQYAKDNFGGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYH2</accession>
    <name>A0A5N6JYH2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Autophagy-related protein 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_009646</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Interacts with ATG1 to form the ATG1-ATG13 kinase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ATG13 family. Fungi subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYH2"/>
    <dbReference type="OrthoDB" id="70161at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034497">
        <property type="term" value="P:protein localization to phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.900.10:FF:000010">
        <property type="entry name" value="Autophagy-related protein 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040182">
        <property type="entry name" value="ATG13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018731">
        <property type="entry name" value="Atg13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13430:SF4">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10033">
        <property type="entry name" value="ATG13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Autophagy-related protein 13 N-terminal" evidence="12">
        <location>
            <begin position="76"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="351"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="444"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="491"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="534"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="601"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="795"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="371"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="508"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="550"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="636"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="795"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="818"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="917"/>
            <end position="932"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8294212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="954" mass="101931" checksum="86A53AF8070384B1" modified="2020-04-22" version="1">MHQYPRSSPITASPASSPRTNPTRTNNPREESRTGYSRTTPDMPHYQEVDDASGDSGVMATAGPSPEAIRKLDQIIQNFHVKAAIIVLGSRVGLPIIFTKEGPKKTNKWFQIETDDTDAYREDLYTWRTCGGFQNRPPPLIIETYLDTSHLTSSQRLVIVDDLGKRWDALDALSDSSGSSDGGSEVILERWKIELRDIPGEQTHDFGSILPNIYKKCIVFFRALYSTAKLVPAWKFKKNLGKNGSPTNALIINCRITTGDTQPRRIDGLKQPIFDHNGPVTSTYLLGKTDTPAGPIFAEVTYRNDCNFRVDDSESLLSSRFMGADEHFFTPSLAARGDLAARGDLSRRRSLKQTELGSLPAQKQLADDSGPVQTYGSLSTFHGNAPPRGSSPISALRAQRPMGSDTSSPPVGSLPPSRPSIGSKGSLKSLEGIAMARRPSLSFQPFKAGSLSSSPSRATYAGETLPASPGSLPRVSGISALAQARNRSSLTAGMPATLRGGPVASDNAIPTSVSSSPKPAPIVKYSSSFVHRRGRSSYGGASKLVDDDQGSSGKQSLSSSVQPGSGILAEAGTGGSSGSLQTDDDNISEFLKLLDSKKTLQSFEPSGEASRKRATAQLSKFQSMRESHNALTDSMASSTMLQRSSASSSRQLSGVSPMVAATSFSVSSSPGKPISPHTPHTPAIPSRLSANSIAEYDQPRRISRRSKTTEARLEDVQDNNDQSNDAGTTAIDIPTSPRPYYPHNRRSSSVAQQHRPMAIEDDLGDLPFGVHRSISLGADDREPPSLSALLNIGQASDDATSPNSQSPSLHQTAPRISEGSTAMSRQGSSSLEAHDSEAPQLSRFSGPGSANSPYRPRLGKSGGRGVTPPQTGSFSSLLVDRGSASGSERAGGGRYSFSRGMGPYEPDDEPLLFDMSEIGRDLSRRSIDEPRGGCEANRGGDSGSSSRRGSRWGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYI7</accession>
    <name>A0A5N6JYI7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_009598</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYI7"/>
    <dbReference type="OrthoDB" id="7295497at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF19">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="441"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="535"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="17"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="216"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="326"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="482"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="352"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="411"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="486"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8294157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="577" mass="64250" checksum="A000D3284EA4A57A" modified="2020-04-22" version="1">MLSGQFNGNFIANVQATTPSRPYHQRESSLSTLGSPGAPASPFAPSTSNPLVVGDSYHEFPEYPHTYQKSLTPTHTPLQTNPRWPGTPTYTQNQNNLTSTMSNINETQRLMCGNNELMAAPEFHSPRSNRPSLTTVASNDSPATPTSHEDERQQFAQGSLSRQMPKLTRTTTDAYDDELYLGYPTVSTPSPAHASTRTSSAPANDIFAQRLQAANQQHLTSNKEKSSALSPREQSPFQHGSPLAPSTASFNPQSTFGSATRMRQEQKVKDAWAIQEQYERANSEQVTPKTISPKDVDLVYHEEDDANIQSFPPLPMSYRSQSIIPHEPSESEDMSLSQQSYGSMATTRRESSSAYSTSSQSTSRQSQMAFNTSQTPTVPQHYPFVPSTQRQTSNMSNVSNMSDMSHDFPATMTSMESGNSEYSPGQEIQRPSKTSANSGTYTCTYHGCTLRFDTPTKLQQHKKEGHRNSTSLINNMGGESRGGMTSMAQKLNSQSGPHQCTQMNPSTNKPCNIVFSRPYDLTRHEHTIHSMKDKLRCEYCTEDKTFSRNDALNRHMRVIHPDIKVPEKERKKKKDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYI8</accession>
    <name>A0A5N6JYI8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYI8"/>
    <dbReference type="OrthoDB" id="5401902at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="537"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="605"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="800"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="800"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8294115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="863" mass="93739" checksum="F718A93DA940A2F4" modified="2020-04-22" version="1">MHPSGQLFTMMPHQGQAQQTSMTPVLPLQLPSTEQTLQQHRDHLMMLEAHISRHSLQSVPYWATQRQILMGEIARMTGLLQSERNSSSSSQAEQGQSHTSVDFGGSLDALPSRNEACSPVVASSNASTIVRSREPPISHVNPVPHTTRSADSPTVKQAATTKVGAGSRLPATAAMAPPFQPRGSRLDLSAAEWEEFARVTDPRPGGRTSPPATPENTTQRLARLMGNCQTRWEDSAVGSSMISMPRSQTMPVPQFQSHATSLPSLRRSDTYPNSVTQMSSMTYGPIVNSSNIGTQSYGRVHTQSHETERFLAQKEYFGNSANSFSNHASSTRQAQRYDTGRQNTMPTLPVRGNYNNQNAFTTNEYLAKCQSMFLPISNQTGVTKYASPWPSPVRNSVNHNTLDFRARSNRPAPPFSLTTQSVINEPVTGAQEDSSDNNVENPRVISTDAQGLDLLANVFAETPQKYLNSDEQPGVLQGHQSDHNSSIQQVTNSRPLTRNDLGAIFASGDRDKPAQSANPPIVRQHTSEDLAVVFASEEPHALTPRQVTKSASGGELTPKDLGDIFASNETGISASSYKIEQPPTPLNNRPHTSEDLGIIFASNEPRRSASKRITKPASAPSLTPEDLGNIFASEKLQASPNYQTKQNLSVRPHTSAHLGGIFASNSPIKRNQGTVTPTYMNGDDVDDNKSIGSWTRRVEHRTSASAQSGNEKENLIFPPKTQDGSPKSKSSFIERLRITSSAVQKNQILKNLLNLQPATHSAVAAPAHVSSANAQGIVPLQNRGSAAASLAPAMVSMTSTSKHSTVTSPRGFASPSTPENRSLSRLSQSFHRSPEHLGNEDYLNCLKEIARHTSLKRSQAENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K004</accession>
    <name>A0A5N6K004_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F5/8 type C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_007057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K004"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF68">
        <property type="entry name" value="GALACTOSE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="F5/8 type C" evidence="2">
        <location>
            <begin position="58"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8295126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="690" mass="73191" checksum="31B9D690CB252AFE" modified="2020-04-22" version="1">METSSLYIQIRPFASIVFHSYLSNIERLDVIYLPELSDILGSFSLKSYTHLLSANMLKLLPFLLLPVTQTVQAAMSIAVSTNQATNPASYAIDGNSSTFWHSEYSPVLVPLPHVIYLDTGSSQLLDGFTYLPRQDGNPNGNIGSYSLAVSADNKTWTTVAASTFKDDASLKSVGFNNTQARYFRLNATSEAGNRGNWTSAAEFGFSLAPSAAGELGDWGPVISMPLVPVAGFVEYSTGNIWTFAAYSPISFQAGLHGYTISAVYNPTTGSVSSANISNTHHDMFCPGISLLFDGRAIVTGGDTADKTSIYTSSANTWVTGPAMQIPRGYQSTATTSTGKVFNIGGSWSGGHGGKNGEIYDPASNTWSLLPGCPVAPMLTADAQGAFRTDNHAWLFSWKNGSVFQAGPSKAMNWYGTTGTGSQVAAGLRNSDTDSMCGNAVMYDAVNGKIFTAGGSTSYQNSEATNNVHLITIGTPHVAPTVQTLTSMTYKRAFANGVVLPDGKVIVTGGQPYAVPFTDTNAVLTPELWDPATQTFTILPPHTIPRTYHSMALLMLDGRVFTGGGGLCGSCATNHADAQIYSPAYLFNTNGTLANRPVISSATSTVAVGGTVTIQTDSEVTTFSMTRYGSATHTVNTDQRRIPLKPVTTNGNTYTFTIPADPGIALPGYWMFWAINSAGVPSVASTIKITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K007</accession>
    <name>A0A5N6K007_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_007056</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K007"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF105">
        <property type="entry name" value="COPPER RADICAL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024937115" description="WSC domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="40"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="144"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="355"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="467"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8295124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1086" mass="115863" checksum="84A1ADED0E2F8173" modified="2020-04-22" version="1">MNLFRSAAVTLLVTFLASFSAAFDHAIYDSLAVPRALLDAWNFQGCYVDVGRTLFEAEYIDHVNMTDETCISYCTSKDLNYAGTEYSSECYCGNALATGAKPAPASDCSMKCSGDASEWCGGPNRLNLYWNGENAPQTNPGSGLWNFLGCYTEGQGGRLLIYQTVSTGRASGMTVDVCTAACQSGGYSLAGVEYADECWCGNQLSNGGTLAPEGDCATLCTGNSSEFCGGTNRFDIYDFNNTAIVTAPFITTTAVAAPSSTSSPSIQQTSHAKQAALGMNILEQNMDENVSYCGNVFSAGSISVPNSDCSFPCAGNSSEFCGASGMLTVYQLNVTLSSTVPPSNASSIVTDLPSGWIYSGCWIDGAEGRVLLNQQPDNQNLTVESCVVTCSGLSYNVAGMEYSSECFCGNYIENMGALALSPADCDMACSGNGNETCGAGNRLSVYSFGSVKIAPPASVQKRDLPGDWNYHGCLEDNIGGSRTFPYQIISANNTATNCLSQCQTFGYNAAGLEYGSQCFCGDLENIKTTGASLISESNCQVVCSGNSTAICGGDSLLYYYSWDGPALYNWSFPSGTDAGEYSLLIGGVCIPLMISQMITGKVTFVEKFGTGEPNSTGAYELDLSAINNFTLAWRPMHVKTDVFCSAGLILPDITGRQINIGGWSAESTYGIRFYWPDGSPGIWGTNDWQENVNEVRLLVARWYPTAMIMANGSILVVGGEIGSNSPASPSLELLPPTGAPVLNLEFLAQTDPNNLYPFLAVIPSGIFIVYYNEARILDETTFKTIKILPNIPGAVNDPNGGRNYPLEGAMVLLPQVYPFTDLLGVLICGGSTPGGGFAIDNCVSMQPEAENATWVIERMPSRRVMPCLASLPDGTTLILNGAHHGVAGFGLGSDPNFNAVLYDPRLPINSRMSIMANTSVARLYHSEAILLLDGRVMVSGSDPQENVHPEEYRVEVFTPPYLLSGLPRPSFFLNNTDWAYSQEIPFAITSNYTSTMNVVVSILGSVVSTHGNSMGQRILFPQMTCGFNSTCTITVPPNAHICPPGWYMVFVLDGPTPSIGQWVRIGGDPGKLGNWPKAPDFNIPGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K015</accession>
    <name>A0A5N6K015_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_006989</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K015"/>
    <dbReference type="OrthoDB" id="18472at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000319">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF417">
        <property type="entry name" value="CELL CYCLE PROTEIN KINASE DBF2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="148"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8295049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="246" mass="28560" checksum="0E66C9FCA9573126" modified="2020-04-22" version="1">MRVKLEKVGETYVPFGKPIEERTVAERREGYRSLRNKDVNYAKSIVGSPDYMAPEVLKGDEYDYSVDYWSLGCMHFESLTGFPPFAGSTVDETWKNLKHWREVLKRPVWEDPNYFISNRTWNFITSCITSKIKRFSNISEVYGHQYFAEVDWNTLRSQRAPFVPELDSETDAGYFDDFSNEADMAKYKEVHDKQTALENMADREDAMSKSLFVGFTFRHRKPNTDDDGKVSPRKAIPTDGTFGTML</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K052</accession>
    <name>A0A5N6K052_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007102</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K052"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8295176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="124" mass="14735" checksum="030C3FFA7F4ACCD4" modified="2020-04-22" version="1">MEDPRYLGTDLQPLSQPESYNLGYLHHKSCAKSLYQPPSRHRWLRSHHVIYKIRLYIDSTCEISTPLKPNGVKLSSFFISFPQEHRMTSPTIFKRLAKNRCNIRRAHKQMREQQLKILTIEEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K056</accession>
    <name>A0A5N6K056_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007102</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K056"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8295174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="99" mass="11181" checksum="BFE3790A9AC84134" modified="2020-04-22" version="1">MDGRNHSGGIINATMDNIFRFFFTRCNVVSLVGRGSKRHGGGIWLRFNATIGINHPNLTPSNPNQPNHWNTLNTSSFKYFQYFTPQTSPQPPNKCQPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1R9</accession>
    <name>A0A5N6K1R9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_008896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1R9"/>
    <dbReference type="OrthoDB" id="244495at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8296098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="103" mass="11479" checksum="F2F5D1045CCB0917" modified="2020-04-22" version="1">MFAQSGGSGWEDNVLMYGANRLYQGGDHDEYKMELDLRFKGLSSLSMLDGSTGTGMSRVGGYGYSMGNLMRRMGWRPGMHCVVLSGSSWGLHDAVRMWLCLWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1S0</accession>
    <name>A0A5N6K1S0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_008904</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1S0"/>
    <dbReference type="OrthoDB" id="2146436at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF1">
        <property type="entry name" value="COPPER ACQUISITION FACTOR BIM1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024822993" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="8">
        <location>
            <begin position="21"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="9">
        <location>
            <begin position="19"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8296107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="227" mass="22895" checksum="B0701C6C2414F712" modified="2020-04-22" version="1">MMARLTALLSLATVVTQCSAHFILNWPVTYGFDDDAEGTAPCGGFSVAYDHNVTEFHVDGDSIAMTSTHPTTTWLFRAIVGNNTAANNWTELIPTVQQTGLGDFCEPTVTVPSTFAGSKGIVNVVADGPDGLLYQCAAVSFVTGAATATPTACKNATGVSASYAADAALSSLPASATATTSETSGTAAASSSSAAGALTVGPIEYGAMGTLMWVGSVGVASFAAFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1S7</accession>
    <name>A0A5N6K1S7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1S7"/>
    <dbReference type="OrthoDB" id="428974at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14502">
        <property type="entry name" value="RNA_5'-triphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000090">
        <property type="entry name" value="Dual specificity phosphatase catalytic domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF25">
        <property type="entry name" value="DUAL SPECIFICITY PHOSPHATASE CATALYTIC DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="281"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="374" mass="41741" checksum="B05B7D2E9D1D1C36" modified="2020-04-22" version="1">MASGSLPVYENHIAKGGLPGENIWKGLDMPVFLVAGEADNITKPGEIEKIAQFLGRPGPVPVEPNDENEPIVNATALTDIPTEIKSTSIRNNLMTEKHILENNSISFTDSSEEPSTPDDFDGAQSIPPQPLRPRKVFKTTLIPAPASHALLYMPSTVRTLAGLISDFLCTQVSPRLSLGWQLQFLSTSGKWDVKNLAKWQAVSPVSEPIAGVFRAMKTLREVDETHCPEVFVKDWGQQIKDIVDISHESPVYDPRGLENGGVRYHKFPTVSKIPPTSDEVATFINLIDRLRDEQAARKEKEGVDDEWFVGVHCHYGFNRTGYFIVCYLVERCGYEVQGAIDEFAKRRPKGIKHAHFMDQLFVRYCVGLKRAPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1S9</accession>
    <name>A0A5N6K1S9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Heme oxygenase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_008911</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1S9"/>
    <dbReference type="OrthoDB" id="652091at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004392">
        <property type="term" value="F:heme oxygenase (decyclizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006788">
        <property type="term" value="P:heme oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19165">
        <property type="entry name" value="HemeO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002051">
        <property type="entry name" value="Haem_Oase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016053">
        <property type="entry name" value="Haem_Oase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10720">
        <property type="entry name" value="HEME OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10720:SF0">
        <property type="entry name" value="HEME OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01126">
        <property type="entry name" value="Heme_oxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="226"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8296117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="472" mass="52038" checksum="2A5DCE09984EF3DF" modified="2020-04-22" version="1">MAEPNIITTHSNSPLPSPPPDQHSLSEQINIATRAVHAQLNRLILLRLPLALPPYTTNPSIYASGILHIAPIYITFESLWQTIIDAPSLPISLEDEQTKSSSPGDRSDSLDSQSSKVCSRTQSLLSHLLLPGLLRSGRLQADIRTLTGTPDHKIEEQLKTVSENGRLAEFIAHTKQSVQTNPHVLLAYAWVLYMALFSGGRYLRAALKMAGGFEDFWDRDASPVRPYEATQAPKPTQSSSKGSSEEEIRQSARRQARSECSQTVKKHGLQFFDFVGDEDGEDIKCEFKRRIAEAEGLLTDGEKADIIKEAQAIFSFMVMMVTELDAICGTMEEALETVKSAPPTKLHRNHKPLNMARGSIALTQERLSKTREEKSSEEEADPMERKPSLYASLVESPMTKLVRFKDGVPGHSSTPRSLPRKYSWISPFAQSGNPSEEINVTASGINPFVGLLTVGGPLVALTAALTTWYYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1T5</accession>
    <name>A0A5N6K1T5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8295994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1T5"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8295994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="120" mass="13389" checksum="1A306FB254EC7AA1" modified="2020-04-22" version="1">MNSNSPIDTIQDGTNEAAPEWSHQNGDTIIPIEKKLDNSTDFLTRPLIGKRKAKRKDDSPLDIICRFVVDHQTGSIPLPDSVSRFLPLTMNSRTICQPFNASFFNAHLLSKSSQAHSQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1T6</accession>
    <name>A0A5N6K1T6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1T6"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="177" mass="20441" checksum="07EEEF9E69508920" modified="2020-04-22" version="1">MPGSTNTIFESAESPCCTAEEDRKDISLSYHNGSLMDKRKWLQGKAQAKAKVKAKVKQGNLGVAHYRMDILPHANKNHSKKQQQQQQQQQQQQQQQQQQRQRQRQQQQQLLLLPLLLLLLLLLPLPPSSPLLQPLLSLQHKDPKEKQKQKIKSTPAQRKNIPVHIHLRGLICWLPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1W5</accession>
    <name>A0A5N6K1W5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-strand DNA deaminase toxin A-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008907</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1W5"/>
    <dbReference type="OrthoDB" id="3497490at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057517">
        <property type="entry name" value="SsdA-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24120">
        <property type="entry name" value="SsdA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Single-strand DNA deaminase toxin A-like C-terminal" evidence="2">
        <location>
            <begin position="96"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="451"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="490"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="620"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="654" mass="73916" checksum="C67D8E91EEEF349E" modified="2020-04-22" version="1">MPEPAHGLTYALRQRSDSIEHISALKKTCKSMARYFQENSVTSFSRPTPINSDEAFFINMGGRVMFIEPIATYKSQVKGKTYGFIRFEGGEVKFKAESGWGPRTRHDDSLRDNEFLSSQVLQFCNYLGYRLPGHCWDKTEIGQYAACHVEKKLILMLICDIIYDVETGDIAMFRLDELWERKLRAQIYLDKDPCNGCRKFALELGNATGIHFRFITAKNVVEAELAKKNGKKQLQPKRTAQTVHSQLFDYSTPRTRPSKPVDYSIPKISTSQKSASRGKRKRTLDDYDGDDDDDETFVPKELQSKAKRLYQEPRKVEKIGITKDKPINYRLGRPTATYEALKNPFTNTPHSWLSQQKNTKADMKSAKTVSPLSFTKNTKASASRSGIMGQDSAAISSGKLPNGQAVPSERSRAIAEFQKAQMSSLARPVKPNLSIFHCVQSLSSISRKETCTTLSDTDSTSSSRSRTVSPEGYPATPTSRTVKIIPTLGTTPSRRYTESSYSERFSAEESMTPSKSFRNSCKRAPTKSLEGLFSEQFPTQEPITPPRSVQKTYKRIRTNYKPAKDVYSETFSAHPTAHSRSVENTYKQTPMRHAVAGSRHSKQNNSRSIDLTTPEPSPFSKIQQFQYTPPSKSNKRREEKKALPVPFQLSYKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1W8</accession>
    <name>A0A5N6K1W8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Microtubule associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1W8"/>
    <dbReference type="OrthoDB" id="642895at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990023">
        <property type="term" value="C:mitotic spindle midzone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051256">
        <property type="term" value="P:mitotic spindle midzone assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007145">
        <property type="entry name" value="MAP65_Ase1_PRC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19321:SF41">
        <property type="entry name" value="FASCETTO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19321">
        <property type="entry name" value="PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03999">
        <property type="entry name" value="MAP65_ASE1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="589"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="617"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="701" mass="79649" checksum="C5D42AE8CB5DBE0B" modified="2020-04-22" version="1">MDTSYLSSQVSTIIDELHGLFDEIGVPSRERESRESELFAALSETLHNQVRLVATEKDDLTEEAHRIITTIKQMEASLEDDKAHLEYESDDDLKVTYPLMQCLQGLKEKHKHISKLHKERFEQVKKLVQALESYSSHLEPSYIQIELPPTSPDASVPPTFDLSNNYVSDLDDEFTRVYEEYNRRVALVKGTAENIIQLWAELGTPQAQTDSAIVKYYRDAPEQLGLHEDDISRLRMKQSELLDEKKGREKRLRDLRTTVEAFNRGCGMRQINEFEDELSRLNELKRQNLHLFVEDARYKLQELWDGLYFSEEEMLEFTPAFSDVYSDALLEAHEQEIERLEALKEQRAPTLALIDEHQSLVKDRDDLQASSQDASRLMMRGQKGEKRDPTRLLREEKMRKRIAKDLPKIAAKLRKVLEDWEEEYGRPFMVHGEPYLDKVEVSEAKPAPGPRRSNSAPRPTPPNRSDSRTPTAGGTLKRHQSSASVSAASESRQATSTIRGKMGPPPSRAPPPKMRDLFEPPPPAPSTQTYYHRNESFASSGSSVRPISPEDVFEAPPKSKERPQSYQDLRSSTRSNFSQSLTYGSAPPASSRQHSMASSSANTASGSENWETYGDVSETEPEEDPNEDYFARLRAARANRFTPDDEAPQFRGSATVNSSMMKKQKGYPLYKGPAGHVLSNDRLCTRIVSGSEANWTDEDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1X0</accession>
    <name>A0A5N6K1X0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8295999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1X0"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8295999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="290" mass="30904" checksum="C146BFFC48BEE073" modified="2020-04-22" version="1">MRIGSNNNKLLTYLSEDSGTQSLGSGTYVDADPNTTLQPGDESSADLKITDLMYNHNSARKRVKLNSQNSYINDDDSTETSPIGPNVSDPFPPFNGLHRALKPKPQHHPEISQGEPSTPPPRSNRQSPITTPSPQLDSRIKTPTSFRLRNPLRSSSIGSNISFEPRGSKSGPGSIGGSGISLGVGRVVGGVVSGLGEGIRGKEDVYTSDVTKSRDDTSASASDTKKENGKGGGSMKTFGGVLRRKSDKKEVNRVTGLSSTGSLIVNIGLIKIFVAFVYRMEGKSAKKLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1X4</accession>
    <name>A0A5N6K1X4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1X4"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024833096" evidence="1">
        <location>
            <begin position="16"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="95" mass="10485" checksum="5737FB454590808B" modified="2020-04-22" version="1">MPFFDLLFAFCLSQGHVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVDVNVDDGQDRINRGKAYRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K220</accession>
    <name>A0A5N6K220_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_008848</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>fluoride(in) = fluoride(out)</text>
            <dbReference type="Rhea" id="RHEA:76159"/>
            <dbReference type="ChEBI" id="CHEBI:17051"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:76160"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K220"/>
    <dbReference type="OrthoDB" id="409792at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="FluC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="FLUORIDE EXPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259:SF1">
        <property type="entry name" value="FLUORIDE EXPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="120"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8296039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="354" mass="39742" checksum="1C31B8ED9B1A6876" modified="2020-04-22" version="1">MVSHDTKVTADYPKSFGDPPHVGRAGDAQQGKYNTQEDHSQINEVATPESMQNMEENPLRQSQSLGRASSREQKARRRASRASKPDSEYDVPDDYAHLNELATPSPVENPREAPIYQHGSLEEAKSAEQDYEQDRRRQERSRRDSIARGEKPLEEEIKDADTKKVSKLATQLYTISYLILFSFFGTLARLGLQAITFYPGAPIIFSELWANVGGSLFMGFLSEDRMLFKEEWGIATYHQKIQKWKAKVKDEENGPGSSPAEQIPDLQAAKKAHAAAKKTIPLYIGLATGFCGSFTSFSSFIRDTFLALSNNLPSPLNHSQDYSPVTASTTSASHIYRVYHFISLASIWIHLRCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K224</accession>
    <name>A0A5N6K224_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal protein L34Ae</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_008880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K224"/>
    <dbReference type="OrthoDB" id="277449at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.370.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008195">
        <property type="entry name" value="Ribosomal_eL34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038562">
        <property type="entry name" value="Ribosomal_eL34_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018065">
        <property type="entry name" value="Ribosomal_eL34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10759">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01199">
        <property type="entry name" value="Ribosomal_L34e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01250">
        <property type="entry name" value="RIBOSOMALL34"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01145">
        <property type="entry name" value="RIBOSOMAL_L34E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8296074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="13097" checksum="1CB27C0F130FDDD5" modified="2020-04-22" version="1">MSSNRLTYRRRNPYNTRSNKVRVVKTPGGELRYLHIKKAGTAPKCGDCGIKLPGIPALRPREYSQISRPKKTVQRAYGGSRCANCVRDRIVRAFLIEEQKIVKKVLKESQQKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K232</accession>
    <name>A0A5N6K232_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008993</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K232"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052578">
        <property type="entry name" value="PI_Transfer_CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824:SF29">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="198" mass="21957" checksum="8315F3CB4AB79BF1" modified="2020-04-22" version="1">MLERCIDLMIPGQFTLALLINFKSSKSKSNTAPGIGQAREVLNILQTHYPERLGRALIINIPWMVNGFFKLITPFIDPLTKEKLKFNDDMKQHVPPQQLWAEFNGELAFEYDHATYWPALLKMCEQRQKDVLERWVQAGKHIGESEIYLKGGGSPSIDGATSEKLSSNGRAVEPKTPGALSEVSGGEVSGKAAQSDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K234</accession>
    <name>A0A5N6K234_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor RfeG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K234"/>
    <dbReference type="OrthoDB" id="4146887at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39609:SF1">
        <property type="entry name" value="RFEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39609">
        <property type="entry name" value="RFEG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="348" mass="38347" checksum="72DEAADE51E3546A" modified="2020-04-22" version="1">MSRRDDRDRASRSQPQASYSSAGRTGQFVIDAEGIDREVITADICRYLGNDALVKPGDVEDPRTKQLKPVYVITAYRNLTNAMIHDLKQASADWRAERLARSSAQYPTNVVDYRSSNALDQSIARMDATQQPRPAAQQGMYNSPSAAVPSSQSYQPSGQGYSAGYSQPTSYQNDGYTQPPSQQYAPSAQGYPTQDTRSYVHGSNYAVEPAGRGGSVPQSVPRTQAVPYPPTTSYQAPAPQYYSQSGPPPSTSAYAAHAPTDPYYSRAAPSGNYETTPEIYDTRAYPETSDYQMQDAGYTEPGSYQETVSYSQPMPSGRSGTATSSSSQRTRDRDSRDDRDRHHQRRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K242</accession>
    <name>A0A5N6K242_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K242"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8296228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="111" mass="11485" checksum="F16CAF31190B2ED2" modified="2020-04-22" version="1">MSTGTSQTGWSERTSCPSRFERDTVMDDTTVQSTIVIHIRIHIHIFITTATATAAAAATATATATATATATATATATATATATSTLPFPFPVTLIIRLRSVGVSSIPYPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K244</accession>
    <name>A0A5N6K244_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_009011</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K244"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF13">
        <property type="entry name" value="RESPIRATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="116"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="955"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="965"/>
            <end position="978"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8296233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1226" mass="134253" checksum="3136E9E960F946AF" modified="2020-04-22" version="1">MREVSIIDQQQSLNMPASTSSNSPESNGGESGGEILGDNVEENESTTSEAASAAVQPADSFPSKTDKPKPHGCVSCGRHFARLEHLKRHERIHTKEKPFACSECGRAFSRRDLQIRHQQKLHSETTPPAKPRDRRTSVASSAGGAGGPHRVQKNSSARSGSMRPRANTLSHVEGAFMQLTMDQMASESLAAESQNRSLHLNHVHSRHPSLAELPMNRDYEFGGVSGIGGMSAAMDHRGMHHGLPKIDTSTSSRTGYLGGLRTAPVPGGFQPADFEFDHNFRNFGFPPGNGSTINPSALHLDDSPLSMAIDSEAFNSHFPDPSAIPMLDDNFAWDPTFNQMNFDAANENAIDGSSPSAISTASYSGISDGIMLDGSNNTAPNTASMWHQPMMGNPLMTPNFVDHGNQHLANFASGNQMSPHILPHNHANSPYFPTPSSLGPSVMPGLNDGLNHTQAFHPPMTLGPETPNSIPGGVHGILPLSTITDSTRSALVTALAQDTSFGGRKFSIPSVNSPSPLSPRFPVRANSVGEITKFLPSTFDLQRYIGAYIKYFHPHLPFLHIPTLSFDLRTYANDGRGAATSIDGPGCLALSMAAIGALYEREHPQAKALFESAKKMLQLYIEERRKADVRRADHRKTSVDHSSRAPQAPVHTPVWLAQAMLLNIIYGFNCGDKVAGDNSLIHCATLVSLAKAADLMRPPPSHNGLPQHEVQMTTGDHVMNGNIKSEIPDDQQEWLNWKVAEERKRTLYAIFILSSMLVSAYNHAPALTNSEIESDLPCDEEFWAAENANSFYAIGGSASADRKKTTFKAALSELLQASNRPQYQQGPNKSFGNGHNAQDLAQNLLEPSAFGCLILINALHNYIWETRQRHTNKAWTNEDTEKMHHHIEPALKAWQSAWQRNPKHCVNRPNPNGVGPLSADSVPLLDLAYIRLFVNMSKSKEKFWQRDFDGMASELSRGNGIVPNEEQSPSSSADSMEFSSGSAASSVAFPYSSPPMSSAALLKRERRLRRAANYAADSLTMSDQFGITFADFTSRELPLQSAMCAFDCAQVIAEWVTSLQERVGCHLGILGKNDIDISQVPDIMLVEVEDMRLLHKIQDILDSAERKMNGLRGLPPIDNCGYGTKILRVTAYMLNRAAVWPVTRIMAHALETQAVHMQTRTESSVIFFFFFERKASPGYLKDKKGLGYACTTKAISLILPSSSFCKKKKKKKKKKPAARPCHILLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K250</accession>
    <name>A0A5N6K250_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K250"/>
    <dbReference type="OrthoDB" id="3535797at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="74"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="346" mass="39386" checksum="10ADA2BD3FB0937D" modified="2020-04-22" version="1">MDDEQDYNSVKPTMETTNPFHWEMHLLAQEFNEREAHQVTDNDNYLADQETLREHNRNVEQLVDRKLAHMAILSKEQELEIDRINKEYSQKLQDVETEYTNKRDIIENELYKKSGKSYKKLQKLHTKNLSQSQEFEDKAKDIFWRMANSLKENNSICVSNSVHETSTTTAVSAAAVETPPVSPASGSTETKNQARMAIRNQYLEASPDEVQPLLDSRPSLEARDTLPYAMTMSQFGFSAPAPQTTHFAYRPSPETFSTKRQKTNYLANTSARGISACSKNGAINTQGDLSIHMPIPPSSMALEETFDPHARPCFSPMKTSGQDLSSRMPAAEKDLYRSRTHYCTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K285</accession>
    <name>A0A5N6K285_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K285"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="93" mass="10874" checksum="E62ADC3023B9768F" modified="2020-04-22" version="1">MIAGDDDDDDDDDDDDDDDDDDDNVIINVKEKQFVLKTHSLHIPLFKELQASSFKKEWKLWKLFKLTNQSIKGNHDELAVPHSYYSRFCKKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K292</accession>
    <name>A0A5N6K292_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K292"/>
    <dbReference type="OrthoDB" id="3693942at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8296278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="67" mass="8139" checksum="034BB844D9A0D81C" modified="2020-04-22" version="1">MFEITQEMVEINRKKSSSTNINVAISYNEYEAQFNMDDWEYASDKIEEWKKKKMEEYVEDDTIEVPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K294</accession>
    <name>A0A5N6K294_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sorting nexin MVP1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Sorting nexin mvp1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_009018</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for vacuolar protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K294"/>
    <dbReference type="OrthoDB" id="10064318at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07597">
        <property type="entry name" value="BAR_SNX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06866">
        <property type="entry name" value="PX_SNX8_Mvp1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000037">
        <property type="entry name" value="Sorting nexin mvp-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000072">
        <property type="entry name" value="Sorting nexin MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028662">
        <property type="entry name" value="SNX8/Mvp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035704">
        <property type="entry name" value="SNX8/Mvp1_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045734">
        <property type="entry name" value="Snx8_BAR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47554">
        <property type="entry name" value="SORTING NEXIN MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47554:SF1">
        <property type="entry name" value="SORTING NEXIN MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19566">
        <property type="entry name" value="Snx8_BAR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="12">
        <location>
            <begin position="349"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="170"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="246"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="298"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00072009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8296241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="722" mass="80420" checksum="17867ACABD5BDB30" modified="2020-04-22" version="1">MSLFGEIDEPVAATNPTKSRLSLFDDEPSSTPGSKSSLFADDDDISGGSPWNTSAPKKLAREDLLKTLLPTSDVPESYIDIFDDMIKDGKVSNGKLSADDVESLLFAARLSSDKISWILTIIIPSGAEPRDLERNEVNVLLALIGLAQEEEDIQYVTLDGVDERRRNLPVPHFITSDPTTASPSNFRPSISDEVPAKPPQRPITPPSVPNSLSPQQNRMLRKDSLEFPESDPWGSPALHKGHNHASLRSNGAPTNGTREPVRTTSNFTTSSAGGSNGSRHQQSIIAPAEPATGGWGSYDTNPNFDNSATPPVGESGGFGGDGGEGERSEEPAPQARTFGGGRVTGNGVEENIVVTLLAEKEGMFLFQHHNYQVTSVRRGSKVVRRYSDFVWLLDCLQKRFPFRQIPLLPPKRVAAAESSFMEKRRRGLARFSNALVRHPVLSQEQLVIMFLTVPTELAVWRKQATISVQEEFVGRPLPPGLEDSLPPTLNDLFTQTRNGIRRSADAYVNMCNLMDRLAKRNEGLAADHLRMALCLQSLTDASQDTYAIDTDDVPLLNEGLHSTAKHLSNCQSLLEDEAKAWDQGVLEDLKRQRDSLVSMRDMFDRRDRYDKDNIPYLERRIQNNENKLVTIRAKPEHLVKPGEIERVTEAIIKDKESIVAQHARGIFIKECIKDELVYFQSTQYNISRLSQDWAQERVKYSELQADNWKQLQEELESMPLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3U7</accession>
    <name>A0A5N6K3U7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_002452</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3U7"/>
    <dbReference type="OrthoDB" id="6407410at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8297058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="98" mass="11286" checksum="6F08B9E47FAF8CE9" modified="2020-04-22" version="1">MAPKFIRWLISMVLDEGGGVSDGKITKREVDIRGWTLGKFLHHDPQYERGGMIWIEDRRRRNGAARVSRDWFHFVGANVFLDDLLDIAPASKTKFEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3V4</accession>
    <name>A0A5N6K3V4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3V4"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="376" mass="42265" checksum="D04DFCEA117B0F15" modified="2020-04-22" version="1">MARLNQPAPYKAPVAPMASSQRSLLEVRKGSKMTAGKSVKKGARGAGPAGPGHGWGVVEEKKEKEREEREEREEREEREEREEREEREEREEREEREEREEREEERQEAREEAREEEREEEREEKKVNEGGNDDSGKDEGGDAVIGGVKPSEAHASVEEEGDGEGETEVSIRKKLQPQEKAIFNPALSRIHTYSKRHAIKSKKLELQSSQQGRREKSAHLETSPKEKQSSSVNKEQSSSLVNKEKSIYDISIQDTPRKGGRSRKLIGGIARSAGQKEIAESSKEPPKPDGEPKDSAKETVPVAEDIEDENGDIQGEAEEVEDKDEEAVAENEVAEDKDESIVNRDQEVNGKGKEGEFEGEVTEDKDEDVEDENEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3V7</accession>
    <name>A0A5N6K3V7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3V7"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="112" mass="12663" checksum="77F6B648C0FEB80A" modified="2020-04-22" version="1">MVRSIGWWRKWCSGFYACKLVSLKLQMLNIYLPSLEDSYDRFVLATDTTIAAATMSTYKVPVPYVSTKTPRQCFRIYHSSSGSFSNPDKKTPAQEYPIATVPGHDSLTSIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3V9</accession>
    <name>A0A5N6K3V9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_002461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3V9"/>
    <dbReference type="OrthoDB" id="1414216at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8297072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="106" mass="12082" checksum="F67F6B2329D44D4F" modified="2020-04-22" version="1">MSFSNSLKEASKVAKTRNDLDVVTQRDAVISIGRRKFIKIHFLNRCINTKFSIAPFTYSVVELAGSFTSDSTSYTYICIVTATRHFFFEENSLINHNFDTFMAGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3X1</accession>
    <name>A0A5N6K3X1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3X1"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF19">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="392"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="426"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8297065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="529" mass="57702" checksum="49C9DAB85C853B08" modified="2020-04-22" version="1">MTESADTYFDPDDVVPRDSPMFKPMHIIYEPEPSPEAHPPPPISPESSPGGRKGGRRSSNRTYQADAVLVSYMGGGKRPDIARNAGNEALPSCEDEDDESPVRGTAVEIPGHEFSPGRTNLDITRKMAADAVDLLRAHEDQAFKNFRDNSQGSIGEAPTVSKSLATTNTSLHAQSATDIPKFSPHSLEPYQKAAPEANIQVETQSSLPPGELPPMRHSPQSGLSNGNGNQPITLPSITPLLGDLNKHAEAAPTPNETSFSQSPGRPTTRFAPGPGATSPARSPNNFRREMISPGRPSFYFVSGNPRRPSQSDGPHYIAAGDYSSSSNTETPSTDQLGSTPATMGIDRMSIDGITNPQVGGFQCTNPGCTAPPFQTQYLLNSHANVHSSNRPHYCTVKGCPRGEGGKGFKRKNEMIRHGLVHDSPGYVCPFCPEREHRYPRPDNLQRHVRVHHTDRDKDDPQLREVLAQRPEGPSRGRRRRGGLDILCHGNLQSISLGWCFDDLRRLDYDFMGGVWSLLIPENGQTCVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K464</accession>
    <name>A0A5N6K464_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K464"/>
    <dbReference type="OrthoDB" id="546632at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="174" mass="18326" checksum="66DBE1CB91BFAF1F" modified="2020-04-22" version="1">MQLQAPRDCSTIQPSLATDVVVVDPPTPKESSQPQRSSEATTEGSNSGSAGEWSAGATTNNKSPFSPSTQATSFASEDSNHDRAVTPTGASPLINSTSHSSVGYDRSSHSTNEGSSMPEGGSDHKVLAETGRNLKKKPSRFRMNGLQFWKRKTGNPPAMPTGTSDKRESDGTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K476</accession>
    <name>A0A5N6K476_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K476"/>
    <dbReference type="OrthoDB" id="4114825at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="237" mass="26457" checksum="01E4C8684915ABDF" modified="2020-04-22" version="1">MIAKANTGGALPVMPELQHPSPRRNTHHEILIEGYGSGFENHYTNHSMRTHTKEGFSMRGFTREGYSMRETIREEQTPHRKPSPSLSMTSSNDVPSQWSDSSHDTDGTSFESSDADSPRTSGSFTTHNRRGSISSTYSDTDSLDQPFGFERLKLLRPTSTTYSVSIYDEDMKAEKPLPSPLFSPTRLPGNRYLGPPPRSILKPSAHRVSVLSQNAHRHASFGSVMVMNEELAAYLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K478</accession>
    <name>A0A5N6K478_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_002547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K478"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8297166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="79" mass="9214" checksum="39CF05DA0965C0B0" modified="2020-04-22" version="1">MPMGSFKLYPRGTIYQFRHTHSIKYHHRHIERNMSLHSTAFRGLNTCLNTSEFNAPSPIIPQILINGVRRDLELLRKGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K482</accession>
    <name>A0A5N6K482_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K482"/>
    <dbReference type="OrthoDB" id="3565171at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="329" mass="38436" checksum="D8702A5D71E5C269" modified="2020-04-22" version="1">MARQERDLKSAKTQAGSLRAEIEVLNQKHKLEMQKQVCQLNETHQKEMDAIKLDLEETEAALQKASTNLQNVRDKNTLVRTERRELDVKLVAVSKDVARLTEDISQLELQKNHALDSAKSLLKSLKESTQHLKTREFKLSLEERNSAVLQREVTSLRDENRRVRKQQSGFTSTSTRLQQLEYRRERDQYEDDAEYYREKRDTVRIELESIEKKLSNTTTKYTNFLRKSERVRLNCKELKKAHDLREPLVKIGVDIRLRFLDQARETIPDVSRDKTDMVLRTNGNFAAHRGNAAADAALFKGTLIPEEYKEEAEEIFKSLYQCPSNRYPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K484</accession>
    <name>A0A5N6K484_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWR1-complex protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_002523</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SWC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K484"/>
    <dbReference type="OrthoDB" id="445677at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011421">
        <property type="entry name" value="BCNT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027124">
        <property type="entry name" value="Swc5/CFDP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407:SF1">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07572">
        <property type="entry name" value="BCNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51279">
        <property type="entry name" value="BCNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BCNT-C" evidence="4">
        <location>
            <begin position="275"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="141"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="143"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8297141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="354" mass="38374" checksum="5A699C855F3705C8" modified="2020-04-22" version="1">MPPELIPSDDEYASSEDEDFAPDAAPAQEESSESEAEDEDSTVVIDKPKKKTTKRKRGDDEEAEDAGFENSGDEAIIERGLKRRKKKGKKGGKDEEGDEGGEGGLIKTRSMRAQEKVEKKPLADTKAATVDVDALWAAMISGKPTPSTTSEPRPSSNSPSKPASPSKSGGKSPELQRDSKERSTFNEGPDSMIKIKRTYHFAGKVITEQKLVPKDSAEAKLFLASQESATAKGGDVGKEAELFVKPKRELKKARRSIFEPVTENLAQQRTDLYFGTAAAARLANGAGAGKEAKKLNTVEKSAMDWAGFVDKEGIKDELDAAGKKKGAYGERQAFLARVEAKKIEDERRARGLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5Y0</accession>
    <name>A0A5N6K5Y0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_001695</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5Y0"/>
    <dbReference type="OrthoDB" id="10263751at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000245">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="17"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8297912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="144" mass="15679" checksum="46868222CFDE04C0" modified="2020-04-22" version="1">MAISIIYGVDKRKSPKPPINQSHPSHHITSIYKSFVKMGVHNIANAAEFKAALESHEIVVLDAYATWCGPCKAISPKVSAFSEQYTKAYFIKVDVDEVPDVSQELGIRAMPTFIIFKNGEKLSQVVGASPHTVEQAIINAVGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5Y5</accession>
    <name>A0A5N6K5Y5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5Y5"/>
    <dbReference type="OrthoDB" id="9930022at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8297950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="99" mass="11498" checksum="E8A71DA6DC4AD4A0" modified="2020-04-22" version="1">MLLASSPWLTRRCLLWMRLRRLINICGTRNILASWPSKSIKTRMSACPVKMSCQDVMSECQVACEDFISPIICTSIPIPYRQEQTLTDTYIKYIHTIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5Y6</accession>
    <name>A0A5N6K5Y6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCA tRNA nucleotidyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5Y6"/>
    <dbReference type="OrthoDB" id="445712at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CC tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734:SF5">
        <property type="entry name" value="CCA TRNA NUCLEOTIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734">
        <property type="entry name" value="TRNA-NUCLEOTIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81891">
        <property type="entry name" value="Poly A polymerase C-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="24764" checksum="184C14BB5B881BB6" modified="2020-04-22" version="1">MKSNETPGSIYKSLVRSDDAKYLAWILAALTPWTAIPPAQATKPGGKIPQPYGFLVAREGLKAEIKLCNIAAGAFKQYAEITELKASIQRNDPHIHQRDVVGMMIRKWDSQGGQWKLQALFALLVEALKLKSAEGYELLFSEWQRFIDHLKELDVMDAPAIRGIVDGKILSKALGVKPGKWMGPALDVCMEWQLRNPDSTDAEVAIEEVRKRQKELDIPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5Z0</accession>
    <name>A0A5N6K5Z0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5Z0"/>
    <dbReference type="OrthoDB" id="125347at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="427" mass="46438" checksum="A123853E663A69E2" modified="2020-04-22" version="1">MSIPGQVLPVLPKVQRNSASRLQFLMGILPKLMTITKETTPVEIRDCLMREFGAEVHLQQCRRAKTEILKKGGSGDEGSGGGGQGGGQGGGLGSDGPVPGNGSGNGSGNVNGGGSNNSSSKQQQHNNNNNNNNNNNNNNNNNSNNSNSGMPGTNLPPNQVLFPDMNAHTNRPPSTVNVPMNSAPPSQPPPRVEPPSTNRTGTSGSSPQFTLHAAQAIGNPAIPERTDATLMQANTMSGHGVVTEQPIRCPYCINQRWMRSIKDAVEHMNIHPHRAKVNKNLIITTCYSTTTTIIFSSFLSFSSPFPPLLAIFSSDQSVLKSHRKRKITSQMVTVRISTLHFQSQMKHPWYVLPAPLPSMNHPPNMQPNEQPKISGLPLSRKQKKKSITKGGIKNKKRHNKNAECLPIFSSFANRKFSQGKKRVWYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6A2</accession>
    <name>A0A5N6K6A2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_001873</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6A2"/>
    <dbReference type="OrthoDB" id="3564358at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33734">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING GPI-ANCHORED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33734:SF22">
        <property type="entry name" value="MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025070804" description="LysM domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="568"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="637"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="699"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="349"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8298111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="743" mass="76421" checksum="9D7F61597DDEF494" modified="2020-04-22" version="1">MWYNRILPIAAVGYVSMTVAFASPLPTAEGVQMVAPQDECLLPDIINPGCIVPDCSLPKVPHPDCGHDGSYHHHHSQEPTSTSYSSAPSSSSSAQSEEPGYAPYPTVPFVPSVPSSTSSTKSRGPAYAPYAPYSTPSTVLSSTSSTESVSSTKSSSSTESEEPGYAPYPTVPFVPSVPSSASSTEDLSSTESLPSTSSEVPSYAPYPTVAISSSVPSSSSSTQNPSSISPTIASSTGYDFLPSTLSTVSISSSNSPSSSIAAASSTNGYGNPFAPYPPYIPSFSSGLSSTGESISTPISSIHPPYPTANNASTTASHPTETNSISTFPLSIFTPPVPAAPTGNNTSTATISTEGSSPTSSTSYCSTLTITLTINPSTEASSEQASPTDEPGFPYAPYPNYHNATTLTTSSSQASSEPSATGGYGYPYAPYPTYHNASTTAGPTSTEGLPSTLTKASSQQSSATGESGYSYAPYPTYHNASTTAGPTGTVGLPSTSSYPLYPTFNNASTTAGPTGTVGLPSTSLVSSSQGSSTSEYCSSATSYCQTLTVTVTAAVTPTSSSSPYKYTPHKYTVKQNDVFYDVAQAHGLTVTQLEDLNPQVANDDIIQPGDVLTVKPNSYDAAPNTPDRIALFASPSPSGYTVKQGDQLIDIAHKHGLTLAAIQASNPQMSANYNMIQPGQVLSLEPSNDTPSSVSKAMSHKVTVKQGDTLSSIAKANGVPLEDLIAANPNIANPNSIVPAQVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K6A4</accession>
    <name>A0A5N6K6A4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CTLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_001875</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K6A4"/>
    <dbReference type="OrthoDB" id="2415936at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTLH" evidence="3">
        <location>
            <begin position="74"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8298115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="262" mass="29245" checksum="C97F12FD200BB0DE" modified="2020-04-22" version="1">MASSTAVTPTPSRLNTFERPPSRTEFERRVTNVKPVKSDINALILDYLTTEGYPSAAAKFSKEANLKPQQEEEHIKARQSIQHSIHLGSIQDAIEALNELEPQVLENNPALHFSLLRLQLVELIRNCNATPDFDITPALNFATTQLAPRAPANAEFLEDLERTMALLVFPPDKLEPQLEALLHPDLRRSVADKVNKAILQSQNQRRDAAIRDLVRLRAWAETTARDAKKDIPDLIELGLDGDNGDDNIHGNGSHAHEAMMMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8A3</accession>
    <name>A0A5N6K8A3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_001120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8A3"/>
    <dbReference type="OrthoDB" id="67317at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056552">
        <property type="entry name" value="Ribonucl_Kappa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026770">
        <property type="entry name" value="RNase_K"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31733">
        <property type="entry name" value="RIBONUCLEASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23489">
        <property type="entry name" value="V-ATPase_su_f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8298980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="150" mass="16416" checksum="3C0A840E07484715" modified="2020-04-22" version="1">MKFHDYPCLSDSPTFNDSFNSIIIQPSTTYTNHTPHNPIKSSAELTSTYSHLTIREAKLYNKMKPVVGVMQAWSCIVISVFAIIILSVIGSLFKSNNHALLGGKEDPEDGAAVAATVFSAVVVYAVFIIGCGFQAYLHFRDNRRGAISLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8A5</accession>
    <name>A0A5N6K8A5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8A5"/>
    <dbReference type="OrthoDB" id="5151921at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="292" mass="32520" checksum="0A6CC258D735F3F7" modified="2020-04-22" version="1">MYSDLPPESQEFLPDPVATPTQRLKKPGQERGRTRSFNTHSTSVSPVHNNYPNYEDILARSPAREQLGQQRPFLLILPHGSTANSQSSRSSTPPIPPPKDEPVISIDSTIVPLSSDEFLQLNENIDIDRFPLPPSPPQHSLEWYRNRNLSVATDDGLQRSGTGRSLVSAVSQISDSPSQAQTDNLAQNILHVDGENNMKRDSGNLYDTSPELPREHMKLVGRYTRRQGETEMSNRGSYDAGAEDGGDINQEVKNECVEKETDRPKEERLQMSATSYPGMEWNPYAAGYAGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8E3</accession>
    <name>A0A5N6K8E3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8E3"/>
    <dbReference type="OrthoDB" id="5393606at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="66" mass="7423" checksum="79ECAAA8BAAFA589" modified="2020-04-22" version="1">MRSLSSQGSSRLTGRRKPQDGSTKLEDRPNLSEEQIGIDRLGEHYSMQDVRRNGILKSDSYSVTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K8E4</accession>
    <name>A0A5N6K8E4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Basic proline-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K8E4"/>
    <dbReference type="OrthoDB" id="5400063at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="53037" checksum="27DC74E0F456E22B" modified="2020-04-22" version="1">MQATRKVPSCCFDTLILWYFKDGGGSYLRCRRDTIGCYKRCVHRAWGGNQQLERERQRGTETETERERHTRAHTNTHIFKKLNKQNLIISPLHITANKKSRPNYYLNFFIVHSPKIPIPCRYWALAKVAVIMEPVPELHSLEEFRASPVPRLRLQESALYDSQTPIKNRDQSGRPPTLRRTTEPIPQSPRSPVWSSPVTPSIPFRPRNTSPYARGHFRSRSNGSALAPPISRAQSLPGVNGAGHLLMSPQRPASPLASPARVRIPRKPADEVFPGFPNRTLIDISEGGQALIEEDASKVSDRSASPILGIPSTGSYTRVRRPGSPLRHLAPASPTTSGTTPTTPSPSTSSPSPYTAKFSESYLTSNSSTSSLYYPGSYASSSVPSTPTSTRSRSPSISSLETIPDTPDAEEAALEAERIAQLKAAADAADGVESEDAKSRGLDGSGGRGRVLGGFGSRDKRKRWSVCGAERRGDLNLDTIWED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KA02</accession>
    <name>A0A5N6KA02_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000256</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KA02"/>
    <dbReference type="OrthoDB" id="992776at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46100">
        <property type="entry name" value="IMP2'P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46100:SF4">
        <property type="entry name" value="USPA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="573"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="695" mass="75273" checksum="D33D1299A663C7E7" modified="2020-04-22" version="1">MTSKNISQESAAEQERQEVLALLDSTGSRSRGSVSSTGSGHRIAGGRTITRHASISGSNSGITAPQIRSMLDVYTPLPAAPAVRSMLDISTPVSTAPISRSAQTSPTTTTTTTTTTNHKAHSDNGRHSRSSSDVAARSTVEFGPRAITRVDPNEYQFSGYLPSNPGGPSVPKRNTQAGKRITNSMAEVVRAGVDLGGFGGRDRKRHNSITGTGINATKSKPPHNRFSPHSASPAPVDPSKYAVLDNGRVIDVNSAYQRLSDANLARSNGELSSLSQKSRQKSPNNEYFDLNGPRLKKDYVPMEGEEGVIDSTDESDDEGPRGRKKKARSVDGDESEMENKTLEMGRAKGQDVAAKEALNEKYKVKSLLDPQINLTGPAGHKLNKPVVHPHTSFDPDGSADPSPHDSDIDADRGDVKKAQSLSLTMTAIKSTPVTSRCVRTIQRGDFKKVQQEARDNQRRTRKYLVATDLSDEAAHALEWTIGTVLRDGDTMLAIYCVDEELGMMTPDNSGDDAQIKQQISAIAAAQRSARASRANTPMLTPSLGPSALNHSFRLESGSRAASPMGRDSRSKAEQDRFRAVEDITDRVSELLRKTKLQVQVNIEVLHCKNPKHLITEVIDYINPTLVILGSRGRSALKGVILGSFSNYLVTKSSVPVMVARKRLRKHSKQKRTPNIRLANNLTNPVVKSLASAKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KA26</accession>
    <name>A0A5N6KA26_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8299994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KA26"/>
    <dbReference type="OrthoDB" id="5367052at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8299994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="506" mass="57799" checksum="EF47118681B89FA5" modified="2020-04-22" version="1">MGMPKELREALQFAEGDQSSGSPLENTFGGPSNPANLGPNEYPPEKVGFREPSQVSPVFQPVIPPTLVPRTPFTPNPEHLDVSRLVTLPPPYPRHHPAVNNNHPDLTDIRTTVRTLSNLAEVTATKERFLRDSAQMQEHQTTAASKRRASLRLRIQRDIEAGTISYADAAAYEADSVTSELLKSKEAAKSIFELFQSQVVLPVNELLMTRIQSATDIFEQLRSKLFNDSRDQNPTSTQEEGDEQPELIEKLTLLKWIFEAREQLHREVYELLSDRNDRYKEMIVTPYRLSNNVERVRGAESFFAEDAQKRKQAFESEILKRTEEFMDIIEENVVRGVEVQLGAFWDIAPSLSRLIEQIPKDRDLEGFMIQIPKDEYEENPSYYDFPMQYLYTLLVHTGKSTYQFIESQTNLLCLLHEVKVGVTAANCRLMGTQRVAQGEGKEEVERELEDVKREEEGRLTDDLKEKVKVVEELWRSGLGTELEGVQGRILRWLKRVGGELPPDDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KA27</accession>
    <name>A0A5N6KA27_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Signal recognition particle SRP19 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_000276</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KA27"/>
    <dbReference type="OrthoDB" id="2190947at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006617">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.30:FF:000003">
        <property type="entry name" value="Signal recognition particle SEC65 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.30">
        <property type="entry name" value="Signal recognition particle, SRP19-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002778">
        <property type="entry name" value="Signal_recog_particle_SRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036521">
        <property type="entry name" value="SRP19-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453:SF0">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01922">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69695">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="188"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="255"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="202"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="255"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8300037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="30767" checksum="1B40B68428E4DDBF" modified="2020-04-22" version="1">MSHARIEEVEDSDNEYGASDPSEGDISDVASDFSDRDIIKKRTPAPSSTKHAPPPNAKSSQMNPANIPFSGSQITTGADGTQFRSTEDSSKYKDFQCIYPIYFDATRSRAEGRRVGIELAVKNPVAREIVAACSRLRIETLFEPVKTHPKDWANPGRVKVNIRGGGNPAIKNKHHLYILITKHLKDNPTTDKTAMQPQLAGIPPPDPSKPLPRPAVPKGWKMGEILPYYSAALSGGGVSENFFKDMMAEMGGQMPGMAGMMDGPSSSASSEPKKKDKKKKIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBR4</accession>
    <name>A0A5N6KBR4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cyclin-dependent kinase</fullName>
            <ecNumber evidence="1">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_000436</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="1"/>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBR4"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF107">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 11A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="126"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8300219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="311" mass="34966" checksum="C3C71BBC40980879" modified="2020-04-22" version="1">MTQLVVTLWYRSPELLLGEERYGKSVDMWSVGCNEVDQLSKIFELLGLPTEATWPSFKRLPNARSLRLPKNPNPATQGSVLRSKFPFLTSAGSSLLSSLLSLNPAKRPSAQEVLEHEYFKEDPKMKSRDMFPTFPSKAGLEKKRRRGTPDAPQRGEAPKGLGGVLDFSGVLSERIKMANLAVGMGQCIIWMYILRGTRGYTNLSVYFEKAISHDFISLDLLCTYSRTWNQHEDLLSSITWQLALNHSLNSSRLLPAIYACIQSAKSIKCTYTPKPPNTITPTQIFLFQNLAQRNVRCMPSNISSCFDPILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBS2</accession>
    <name>A0A5N6KBS2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8300893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBS2"/>
    <dbReference type="OrthoDB" id="446168at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="157" mass="17134" checksum="E9FDEFD4EBF04C49" modified="2020-04-22" version="1">MYGSPLTLILPRKKTSDEFLPTALQLQSIEYHKRGPITLPVLSTRTYAILTFGGAITVLSGKVLIVSGVNLLLTRKLTASLIQQYGRKLTKAIKKYHAILGPDGGDKMVATRARGVITLNEAAPVTILEDLIAPRVTRYVGINHGVDDLRVVCKDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBS4</accession>
    <name>A0A5N6KBS4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rap-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_000445</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBS4"/>
    <dbReference type="OrthoDB" id="19311at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033596">
        <property type="term" value="C:TSC1-TSC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032007">
        <property type="term" value="P:negative regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051056">
        <property type="term" value="P:regulation of small GTPase mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11210">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035974">
        <property type="entry name" value="Rap/Ran-GAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000331">
        <property type="entry name" value="Rap/Ran_GAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027107">
        <property type="entry name" value="Tuberin/Ral-act_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063">
        <property type="entry name" value="TUBERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063:SF0">
        <property type="entry name" value="TUBERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02145">
        <property type="entry name" value="Rap_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111347">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50085">
        <property type="entry name" value="RAPGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rap-GAP" evidence="3">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8300229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="228" mass="25666" checksum="5D2E924C91A99959" modified="2020-04-22" version="1">MPTNLEHDPQCAHKKKHIGNDFVNIIFNNSGLPFKYDTFPSDFNYVNIVIAPESRLSFTAARDPRQGQLRKDPYYKVQVMSKPGFPEISPAADMKIISLRKLPEFIRLLAMNASVFSSVWANREGGEHVSPWRNRLREINRLRAKHAPKRSNSNQVSPPGTSNGGVSDAKNRESMTSIRRASVANFSFLSSSLDASSQRSSVMSTAEPERDTNGNEQMVYSLDFSRWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBU6</accession>
    <name>A0A5N6KBU6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBU6"/>
    <dbReference type="OrthoDB" id="5405745at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024338">
        <property type="entry name" value="MID1/Yam8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39142:SF1">
        <property type="entry name" value="AEL197CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39142">
        <property type="entry name" value="MID1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12929">
        <property type="entry name" value="Mid1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="442" mass="47827" checksum="1ACD432033FD4861" modified="2020-04-22" version="1">MPLPKLSPLQSRLAASLMGSIMLLILYLAFSSSHFAYAADVNSIRPEDHNHERLIDLTMLEPDDEDEDVGPRLDGYEAEFVGFDRSIIGRVASANDPTPLINNRVVTTNIEQGHTIPFSFLNSSLWGALSPQASSLPSPFRFRKRNSESAGNMGGEGFKNSDSEFLEVEDGEQVLTQDGETNSTLWPRQSSSTSTRTLYITVNTCTQPEAKQANLAAPSQLELYISQSEKNKNPRPGQDDSLQQIYKLDGGAAMITLNATGDVYIGLSGSNLTENYTGTWNAQIAASIDAPYHYYNSDESNLVLVDSDKGSALLVTNDLTTDNGSLYDEWVNLIPPFTMFASKTANSSIAGLQYSYCGLEKKAEIAGTINGGQSTGKIQVSMTTRGEDNYPKQQLYLDGLTPGTSYYGVLAMTGNTTALGREGVGAGGQVWKAMSFSTISGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBU9</accession>
    <name>A0A5N6KBU9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD40 repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_002823</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8300896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBU9"/>
    <dbReference type="OrthoDB" id="5321461at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055525">
        <property type="entry name" value="DUF7099"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055526">
        <property type="entry name" value="DUF7100"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055527">
        <property type="entry name" value="DUF7101"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23388">
        <property type="entry name" value="DUF7099"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23391">
        <property type="entry name" value="DUF7100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23392">
        <property type="entry name" value="DUF7101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7100" evidence="3">
        <location>
            <begin position="8"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7101" evidence="4">
        <location>
            <begin position="372"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7099" evidence="2">
        <location>
            <begin position="676"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="631"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="561"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8300896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1108" mass="122787" checksum="C3CB06EB372E0E0D" modified="2020-04-22" version="1">MPTPASATSPQFTRLANTWKLLSLRSDIDNIILELVGQFSLEKVYSDGDKETYQHLVITLFAQLNAIFYIQRLSIPSAKFQKDGWYLGFLASWEVTLRTIEFALQIVIEGRESLWESRQLRDKYLAEFLLSALRVLQLLPHAESNSQSQSKGDLQRRDRRDRFARIHRSLEHMYDSYPGVKGFLLLVCKEVTESLRGPEPNPLALPPKLRDELPNLTGELYPLNDCFSTKYVSTLIPPYNASEGGGGGGGGEKGGGWLAQFLALRDITQFVVAASIQYTINGETRDAYLPAASQRTRNAVLRAIENMRIPPRFSKDDLVGTFTDQYRIILPDTPDLRRQSMQIHIDDRELDAIDALCLRLSDRQMISRVSDREMMHTISEITKRILALDDPGRHAKPSRPRIYTLNCSKCHLAGASQMRYLENLKFPLDNPETNEVRLPSKTKCVQCEEPVTLMREMTLARQVWDLLEPFESHADSVNLERHVPTCFQLPPPKTDGGLPFHPAYNNSSASNLKMRTYDTEPPSPFHNKTTFTSAAAQDRSRSLPQTMPPQVSPTVGAFGQRLDTPSTLPSSSSDMTSLDGSRSGEGSKMPELRKTSTATDEMPFSSDYMSNQGSSSLNDQAPSGIICEPGNSFGNRPAVGHSHSDRKKSKGGSKWTSVFTGARKESGAGQTVETTSLSSSALEAQRLDEINLESLVRVPRKTSTKSKTAKAINISLSQNSTNGLCWTQSLIQIWDIGASPPAMTRVFPTESSCYKAAVTKMYLAYIIGTRDPKLTLRIVNLQTAAPIVEYPLPPNLWASSIAISPNETTVAVGFTNATVCFFKTTRSAEPREDRLHSRIHKECDDCPEVDTLSYSDDGIHLLASTRSAKSGAIQIYFWITPMQAAQELVSCRYHVPLHESEDRGLSSAIFRSRTGIEEVLVCVTTWTQSGLPVLVHPKTGQKTEIKTEANRAGKLGSRIQCASFSPSGKELAMVNEKGHLYLISALNSSPLDIRKVAVSRELTIKSDSFAMGFMSLPDEEAAIVMAWIDPSKAERGMVRKIPLTTGDSSMTTTPVLHKSKPSDGLGSGAYMSGALNELPGDSRPIEMVADEEPVTKYRMMGFVKYPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBY3</accession>
    <name>A0A5N6KBY3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBY3"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057334">
        <property type="entry name" value="PH_2nd_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25353">
        <property type="entry name" value="PH_2nd_LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="139"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="397" mass="44391" checksum="132E86533C9F9584" modified="2020-04-22" version="1">MAPKESRRKSLSLLSRASFSNLAHINTDVNNASTGEKEQKEKKKTGKRASLFNNLAAPTIHTNLENGSNHPVKSDAHSPKLRPRTLQKGRPTSIFGSLGRKSMTDVDEEREVTGTTPESPEEEYHYLAAGIINASSAVSILHHGEVQTTSSMFRKKKEYLVLTDTHLTRFKSMARAIEAFPHIQPAHLRQSHRQSSTASIGSLQEVQSQASHTSAEGENRIPLGQIVTVYKMEDGRPFFTTEVVFLDEDYHGVGSIQLMLHDPKEADLWSTSIRAAAQKARLMMPEPYPERVVRYLVQNLEGVDDYDSNHFQVFRVVKRAPLAKSARSSSDDLQKLGSSVFYMVIGINRLHLIPLPDFNLPSGTAFHSKSSRNTYGLVSLVAMNVQYSDDRFELAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBY4</accession>
    <name>A0A5N6KBY4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_002874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8300949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBY4"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8300949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="88" mass="10319" checksum="D38DFBDF7B0FE003" modified="2020-04-22" version="1">MAPPTFPFSTYNSITIDVNPANGSPEYPVIAFRTSIFEIPDNAQEEYQQWLRVLGNFRYWISQWFCFAHVYQGIDILFSRIKRVPLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBZ4</accession>
    <name>A0A5N6KBZ4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="10">2.7.8.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_000495</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>a CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60110"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the CDP-alcohol phosphatidyltransferase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.5" evidence="10"/>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBZ4"/>
    <dbReference type="OrthoDB" id="10250191at2759"/>
    <dbReference type="UniPathway" id="UPA00084">
        <property type="reaction ID" value="UER00503"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09135">
        <property type="entry name" value="PLDc_PGS1_euk_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09137">
        <property type="entry name" value="PLDc_PGS1_euk_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016270">
        <property type="entry name" value="PGS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586:SF1">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000850">
        <property type="entry name" value="Phospholipase_D_PSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="12">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8300299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="515" mass="56579" checksum="16F14F2E502EBDE8" modified="2020-04-22" version="1">MKQRAHSTSASSTAATPTAPSSASILGAFTNDCDKITPKFEVHGSQIQILRTPSEFYETLKSKILAAETRIFLSTLYIGKTEHELISTLQQALRANPHLKLSILTDALRGTRESPSASCASLLAPLVSEFGADRVEIRMYHTPNLNGLRKKYIPKRINEGWGLQHMKLYGVDDEIIISGANLSNDYFTNRQDRYHVFSSKEVTQYFYNIQKAVSSLSFLVSPDPQLPAGYTLEWPSSNSCPSPLTDPPKYISHASSVLTPLIQAPATSTSRSISGNPQANTTIYPISQFTPLFPSTSDKSTELPLLTRLLTLLNSPNTPTSWTFTAGYFNPSPTLTSLLLHTTSKNNTVLTASPHANGFYNSPGISGMLPPAYTLLLRKFLTAAQKIQGPSPSITLREWKRGIVNEPGGWTYHAKGLWVSFPSPSSSPSSETPKPAITVLGSSNYTKRSYTLDLETGVMIVTRDPELQERLRQERDGLGEWANEVGMKEFQSSERRVGLHVRIAMWIVGVVGGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KC33</accession>
    <name>A0A5N6KC33_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">EYC80_002923</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cell cortex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dynactin 150 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KC33"/>
    <dbReference type="OrthoDB" id="2130750at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000743">
        <property type="term" value="P:nuclear migration involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022157">
        <property type="entry name" value="Dynactin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF6">
        <property type="entry name" value="DYNACTIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12455">
        <property type="entry name" value="Dynactin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="10 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0243">Dynein</keyword>
    <keyword evidence="7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="15">
        <location>
            <begin position="29"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="73"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1047"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="204"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAB8301000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1277" mass="142635" checksum="A46D47ACC15FFE01" modified="2020-04-22" version="1">MAEFEIGQTVELGNGAIGTILYIGTDPIFAAGDWIGVELEEGGGKNDGSVLGKRYFQCEMGRGMFVRPSTITVIDRPAPPPKAPAPAKKPGRPTSVIAPVARRTSSVPENGVIKRKSMNAPSPSPMARGPSGLRSPTKQLYSAGASAASTPRTGTPAHSRAPSAGISKPRPSSVTNRSSMGPPPPPSGRGKPLAGGSGVGNRIGGAATRTTGSRSTSLAPKRSLRPGTDRVPSGSSQVSAGHLSDGTHETVDEDILLSPSLRGDTDQLSPQALSPVLSRGGREASPAGSPAAQRGATSTAASREIEDLKTKLRVMEKKRMEDREKLKALENVQAEKEKFEGIIQKLQAKYQPQQQELTDLRKQLKEFAARFEEVEGMQAEHESILEMATLDREMAEETAEVLRTELDALKLKTEELELEVEVLREENTELGGEMSAEEKTSQSYLQMERKNERLTEALLRLRDLTQQAEAELKDEIKSLQEDVRDLGSVKENYDMVKGKLAQSESVIEDLRQQLDNALGAEDMIEELTDRNMSMSEQIEELKVTIEDLESLKELNDELEINHVETEKEMQEEIDFKESIINEQARRAAQQDETLDDMEYTLSRFRELVTNLQSDLEDMRASHAVTETESEQLNSRSRAMQDLNLKLQVSAAKTQVKTIELELRRLDAQEASEHLSIVQLFLPDGFSAERDSILALLRFRRVAFKANLLHGFVKERVNGHPPIGHEDDIFAGCDVLDKLVWVGAMCDRFVNAISHCSIEEFGKYEGALYELEPVERALNGWIDGLRRDELKEKQCASELQRTVALMSHLAEVHISAGLASYADEIHMRTLIMQSQLENAAAAIASTRTMVQAIIPSQEEDDELFQHFSKKTEAVITQTRSAKVIVGKAVREIEDLRARSLSLMPNTVESFEQCEIATQQLADYTRHVGNDLFTLLHEEGRAEPYTYVEVQSTIYQTTSNTLSADESDLFSTYSNKLKLLNNQLIDLSTLTSDLEMTQEFERATAPWILRSQELKSSKTVTIDTQEELRRLKEENHERLRLIALRDQTLEESSVKIELLESRMRDATKKNERINELERRIDIAKKREAELAEAIEVQNKELSTMEADREKWKKIADESKALGEVVSGSKAGQERAVATAREMDVLKTEIAGLQAAVRYLREDNRRVKLSGRENMSWLEEPLIKPKPIEEQRKALVIAEGQDVLSELLTLATGDNSRIYDLGAMQKDRGKWRPAKSTPGYWVAKQREGYEDWRAWKEEVLRKGRVLGEREGKCWEGRGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDV7</accession>
    <name>A0A5N6KDV7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003393</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDV7"/>
    <dbReference type="OrthoDB" id="17927at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="187" mass="21707" checksum="5FF6ABFA92855844" modified="2020-04-22" version="1">MNLRLHPYAPEKLATTPPHTPFSYPHGLHFSAAESPSGILEQAWIMKMASEISRRQHDKTSREGFWSTSRTIPFKLSNVYNISNFSFVYHFTGVQWACLISTGQGRCWTSWEVWLNLDGLGWLGIIRVVGSRSYHDTLGEGEDEGGCCFGFYLYWDFTIPSLTDRFQRRFLELTNFFCLCHFRSERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KE78</accession>
    <name>A0A5N6KE78_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003506</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KE78"/>
    <dbReference type="OrthoDB" id="5290671at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="181" mass="20474" checksum="4BCBDF72D622D3B2" modified="2020-04-22" version="1">MKDYFISTNISNNQINPSQVESNQVKSSQVKSRYSDIMNTSDNPSVELHGNGQRVTLPHEDVGAHTLWKQNSTTRPPIWHVRVTVLKDGDIRGDCPNRIFSFKTLEDATRAINQVEAAFGETFELKKCGIDSPDAMGGRVNDGRSENITIQFDSNVAKEPWNEFLVRLRELEDNWLHAADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGA3</accession>
    <name>A0A5N6KGA3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGA3"/>
    <dbReference type="OrthoDB" id="537467at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="269" mass="30615" checksum="84472699F9055A34" modified="2020-04-22" version="1">MRIFRLVRVLSQIKTCTKKASKKPNNEVKYCSDRCRNRKPGKLDKNIEQVIVALLDQEKESGLEKTGAKDRFVKGDKRVIITCDEIEEIVFGSRFDPENIYGRRKNRKSRAIGGLNADTEWKTVDMESEDSATDDAPLELMDTKSSPMIRPPQSASDVNFSVGGERGRAERTKESASDLKKKVDGQKQAEEREMVRRAARRAVVFGFLTQQSPETASSQVFKGSKHKKSVIWEENIVEEPTRRKCEALMQGSVVEPSFAKGNWSIRWRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGB6</accession>
    <name>A0A5N6KGB6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGB6"/>
    <dbReference type="OrthoDB" id="10264306at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008265">
        <property type="term" value="F:molybdenum cofactor sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043545">
        <property type="term" value="P:molybdopterin cofactor metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF80">
        <property type="entry name" value="MOLYBDENUM COFACTOR SULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="27"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="174" mass="19653" checksum="B902FAB83AE84112" modified="2020-04-22" version="1">MNEHNMEYNKVVEGFRKNEYPMLKDAVYLDHAGTTLYSKSLMERYMMDMMSNLYGNPHSASTSSQLSTSRVENARLSVLRFFNADPADFDVVFVANATAGIKLVMDAFRGQPNGFLYGYHQDSHTSLVGAREDAVSNRCLDDVAVEHQSVRIPSTIELRWSKVTIIMARKGTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGC3</accession>
    <name>A0A5N6KGC3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGC3"/>
    <dbReference type="OrthoDB" id="5294180at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF12">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="501" mass="56382" checksum="B0D93B5111037153" modified="2020-04-22" version="1">MHSSHTQYTNMYPEYSPYEIDVKTERQMFVNDVPTRRESTISTFSTFHPPPPPEAMLPSYPIDHEWDTVYNERHEILAEEALNMNLFDFSHGPPSAFRQVAIELDEGDQRLLDHFISDVLPSVFPILETNQHGSARSDYILPALQSNKCYLHCCLSISAQHFKSIMNIQGEQIDNDIMRHRYATISELCDALNRDTDHVSILEATLGMIFFQCSVGRFDDNLPDIPWHQHFQAAISLVQKLELPRLVTESHDSMSFNMTLTAWIDILGSTVQGRAPTFAHTYREKHLSQTNSSLGLRELMGCEDRVLYLISEIACLEALKNDGMDDIQLCQHVHALGDQIGLTEIGETGPRIPYNSHGVLSPKQLSRNMTAAFRLAARIYLCSLVPGFSPSQESCVGLVAKLTQVLEFIPAGPVGFDRSLVWVYLIGGSVSTTNSPFRQYFAERAAALGDLADHGSFGRVSTLLKEVWGHVDGRFSPGGGEAHYVSWRDVMQMKGWDFLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGC5</accession>
    <name>A0A5N6KGC5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGC5"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="121" mass="13289" checksum="067B6662467BB090" modified="2020-04-22" version="1">MDEGLFAFEEDDDYQTSNDEYGDETENQQWERCNMMQANQDEPASSDIPADQFLNSTYPVDPPSRSSSAPTTAPSNKALTYPKTFYAPTPPSSIAPSTAPSRKPPPKKCTSQKPPSPHSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGC6</accession>
    <name>A0A5N6KGC6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006102</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGC6"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="162" mass="18803" checksum="A15F5AD1D55C830B" modified="2020-04-22" version="1">MKDMVDFNRPRLDRLTKVLHHIIARRLGFALTIPKDTDGLDHIFNQCIQKGIDGFLKVVLSPSHFLKFEEILDKRFANYNDTRSFARSSQHIQLIRDILPGAIEEIIRRRLDSKEASHCASPILLERLFYLAFNSASAQEQYLLTYLPPYLPPYLLPPTSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KGC7</accession>
    <name>A0A5N6KGC7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_006177</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KGC7"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16568">
        <property type="entry name" value="RING-HC_ScPSH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="96"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="308"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="363"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="411"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="507"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="541"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8302840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="615" mass="68739" checksum="EF1B24630BBB138E" modified="2020-04-22" version="1">MNSSSPSLVSTRMSNHGSRISENTARNHDARHSAIKSEPGTRGDIGMKDETDIKIETAIKVERGIKVEKNEPVEGDAQLAKRFRDDLLGMRRSLTCSICDQLLYEPWTLQCGHTYCYSCLCQWFVPNRRKKTCPECRTAVKQMPAPAFLVKHMVEIFMNRGQIMPNDETVEQHKQRHAEETQAVESDKNSPEGLFKGTFPLRHGELWHDEADGVMRCPSCGHEHEGGPTCESCGAEFDDVYGFSDMSDDDDISDLDVGYDDDLQEELEAEMQMGGGGMNGFEYHPGGPFMGGPHHQFLRHYHTHNHGFNLDDATDDSENTSYQGNSEDEDAGSLEDFIAPEDDDSEPVAAPRRANQRVVTIISDDEDDENEYEEGEEEEDEDEDEDDDDDESEEDEGGAVTNRRRPRPGWTRTSNTPSISALNTEDDNGSSTNGSEFGDDDSHETRMRLRASGGWSPLDEGEDDDDEGLVHDHYTGYATTEDERATDESDSETIGNPNSDAEDDDERGGYSESRHYETGNFQQTLDDYPSSMEGDSTPVDYSRERYGESVDFNSEHGDSYDYDTDGGQSTNMDRDGDTEMSSPGLPRSSRSTPLYAPLHVGSRDKTPTFNSTTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIA6</accession>
    <name>A0A5N6KIA6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_006282</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIA6"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001471">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="479"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="595"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="706"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="26"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="484"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="801"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1052"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1090"/>
            <end position="1111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8302969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1111" mass="123103" checksum="FDC05E91BE4650DA" modified="2020-04-22" version="1">MDQVDRGGITKRKEESITPQSCVGDIEVNDVTFAYPSNRQQNALTKTTFFFPAGETTFIVGKSGSGKSTLGNLLLKFYEPQEGNILIDGQQIQDLGTDWLRHKITLVLQQSVIFNETVRKNVEFGKEGETNEADITNACSAASLEQVIADLPNGLDTMIGSKERQLSGGQKQRVALARARLRDAPILILDEGTSALDLTNRLKVMDNIREWRKGKTTIIVTHDISQILDDDYVYVMEQSRVVQEGYRRKLSAKANGTFATFSPLPEAPVGQPMDLSDMRRNSDPGTPLTGSFEEFVQELKPRFSTMSTIYSPNMASRHSLDMSNRRFSLGYASISYANDLKSNEIWTSRIYSPRSRFDDFRRPNSRFQNSHVSDNKSSIYYNSSPRYQEAKFQPISEHLMEDQNLRIQSSIPKPISFSSTNMDRDSRVVLMDSLLEYSDDSIENTEESKPEDEAKHIKPKSLTKILKTVWPMLDERERIILSSGFFAAFIVAAATPAFSVIFARLLDTFYQTDNRSSNAIKWSLALLGVAIIDGTASFCSHYALEHAGQAWVSALRVEALKRILSQPKPWFEESTNSPGRLNEILDRNSEEMRNLVGRFVGIVFTAFFMLLISLIWAFVNTWKLTLVSMACGPVIYAFTKLFNRVSGKWENKCNYASEMTTSIFSETFSNIKVVRAFTLEAYFQEKHTKATQELYKVGRTRANYSGMLWGLTDAMTFFTTATIFYYATVLITKNEISVSTALQTVNLLLFGISNSTNLLAMVPQINSSRVTATHMLGLANLDPSSSHENKGTERLPSIFPINFNHLSFTYPARPETRTLSSISLSIAPNSTTALVGPSGSGKSTIAALLIGLYPPDTSVPPPLTFNQVSITNCHIPSLRASISLVPQTPILFPATILHNIIYGLSESSSFANISSAITAAKDAGIHDFITSLPQSYNTTVGDGGQELSGGQAQRIVIARALVRKPKLLILDEATSGLDGGSAEVVRETVQRLKKREGMATLVVSHTVGMMKIAERVVVMEEGKIVDSGGFEELKNRVAGKFAALIGEGLGNNKTMEEQNDIGEGSSKAVSTANRGSGLGISIPGYEDEMDNVRDTPIRDGRRRETWLRPDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIB2</accession>
    <name>A0A5N6KIB2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_004916</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIB2"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF461">
        <property type="entry name" value="AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="34"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8303504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="300" mass="33189" checksum="9B77FA1239F461D8" modified="2020-04-22" version="1">MGVAAHSAPNYDAVFQSFGIAKAPITHTVWIPSGSTFDSQLSSAMQIVYAYGGAMLYCEFMAEMKRPLDFIKAQFVAEIFIFLCYLIFGLVVYSQQGQFTYNPANQGLSPYAWQTVTNALSLVSGLIAAVLYGNIGIKVIYQNIVEDLFGGPELTTKKGKIIWIAIVPLYWAFAFVLGSAVPQFTNISSLVAAVCIMQFTYTFPTLLYFGMIIKEDAMHPDETFDPATGEVHRIDTWRDMSRWKRGLAPRWWLKVFCFLFFLASAATAVLGMYTSIKSIIADFALGHATSFGCTSPVGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIB6</accession>
    <name>A0A5N6KIB6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIB6"/>
    <dbReference type="OrthoDB" id="2342176at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF2">
        <property type="entry name" value="LYTIC POLYSACCHARIDE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="40546" checksum="295B588EAA0CDE80" modified="2020-04-22" version="1">MIMTNPVPYGVDTLNSSPLLADGSDFPCKQRANTYDVTTENAMDLGGSYDLAFKGSAVHGGGSCQVSITYDEKPNAQSTFKVIHSIVGGCPMRNMVGNAPENANAVDPDTYNFTIPTNIPSGKATLAWTWFNKIGNREMYMNCAPVTFSGGSTKRSDLVERDQAAFDALPDMFVANIGNGCGTADSLDLVFPNPGDSVEFDGGATSTATSTPTGSCAAAKGGAKATGGASSVATSAANSVATSAAPAGTAPASYLPGGVFATVSAGASTPAATSATSVAVSAPSVTKSATSVPAVATSPVSVPTQPASAVAPAGTNSTSSSSSSSSSSSSSSSGGLTGTCASEGMFNCVGGSSFQQCASGTWSVVQSMASGTTCKTGQTMNLAVSKRGDKRVIRHFARRGLYTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIG2</accession>
    <name>A0A5N6KIG2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIG2"/>
    <dbReference type="OrthoDB" id="3548170at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="457" mass="51208" checksum="D544894346DAF202" modified="2020-04-22" version="1">MVYEAHTEVAQFETEPLGPNTGSHLNMQVETQVQENSVGAVDSQCFQQIPSVLRQPQTVASPSVLPTTQVPSLSRAPPSPYSSDSKTVPPPAIPKTGQRKKSSIDRIIEEHDRKSAERLAARKAHALRLGYKGIQKNAGDRNLHRSSRGQDEYVSNPQNRSTSRHHGVPEPMVARQAYHANLQDQLRAQELSESNTFLQMDQMQQSPAALDPFQQMSQNRMTPHQQNYRNTREASQQPPVGTASRPSRYNHQNSQSNMNSFQQTSQQVIDPPMERVFTPNMNSQASGYGNHVPVSHSQSFNSRQLMEPRLQNHSSQRMGQARHGSGPSALNYNAVYEEPHVPLFPERNSWEPPISNIIRGEANNRRQISVSQMQQFEAQQQANTGIPPQAFNHNPAAANEFQMSNNWSTTPIDPFPSMNSEQTPQSLMNNPFPPPPPVQISFTHTPKDRDGFDIPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIG6</accession>
    <name>A0A5N6KIG6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome c oxidase assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_004970</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Required for assembly of cytochrome c oxidase (complex IV).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the COA3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIG6"/>
    <dbReference type="OrthoDB" id="10018333at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041752">
        <property type="entry name" value="Coa3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018628">
        <property type="entry name" value="Coa3_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15642:SF3">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15642">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09813">
        <property type="entry name" value="Coa3_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c oxidase assembly factor 3 mitochondrial coiled-coil" evidence="10">
        <location>
            <begin position="20"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF09813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8303566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="72" mass="7926" checksum="9CEECEABBC4D37DC" modified="2020-04-22" version="1">MPLVPKSSYYDKNYKQSAALIRARRPYLVKNALTGAGIFAFALGVFAFTIRAVSQDEFEDVKVPAAPSKQDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKD6</accession>
    <name>A0A5N6KKD6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_003566</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKD6"/>
    <dbReference type="OrthoDB" id="2119662at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052031">
        <property type="entry name" value="Membrane_Transporter-Flippase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43549:SF2">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN NORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43549">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN YPNP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="453"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8304147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="491" mass="54072" checksum="9ABA9B97AAE37646" modified="2020-04-22" version="1">MVPTKDDDVIAAAIEGVGGEPEEVPHEERQVFSIDKRSLTYPLSHIEVLNEGLPRAVWVIIADESNRSVHSRLTLTYTLVSFQVLLGALLMIIFLSSAEHLAAAFVPEVVREASLTYVRISSVQALSSAMSTAVANSTRALDHPDVPLLISSVQFAINILLDLLIISKFHVGSHTPTVNTQALIRMACDLASAGCGLAYFLYLAFQIPRPTAPQLSTSSHGTDSPLSLTPSLLEADSSPEIEPEPKITFSALKTLFRPGKWTFLESALRNAIYLWLIHGIVSMGLDYATAWGVFNNIRWGIVMVPVNALEASTSAFVGHAWGAWRKDAGIETRKPKAKRSDILKIVHYALISCCIALLIEGTFCIFLSLWGIKKFSFYLSESSAVAAITEHMWRTIDWCYIFYALTTQLAAILLATVPKWYFVQSLGSNLLWMLPWAVAVGRIHMTAENAWTFHGIIFGGALVFDFVNVGVVLGWWVWALRRGKLVVGVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKE1</accession>
    <name>A0A5N6KKE1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKE1"/>
    <dbReference type="OrthoDB" id="2283785at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039634">
        <property type="entry name" value="Bul1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904:SF1">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="1">
        <location>
            <begin position="29"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="263" mass="28507" checksum="DA9F9095DFA49583" modified="2020-04-22" version="1">MSASSVHSGSGTIANYAKKINPTKRPDVEIHIDDHHEGKTYTTFDALSGRALITAPHDAPFDEIQITLEGVTRTYVENISHSSATSKTTAVHRFLKLIMPIPETAYPQPRIAAAGKTYIFPFNFVIPEQLLPTACTHPSDADHVHTAHVQLPSSMGDRELSILDDLAPEMSKIQYSINAKVVKYTEFPKKSTSLVGGSKKLQIIPMVAEAPPMSISEDDKGDYLLSKTKSLRKGMFSGKLGKITVLADQTAAIVLPPPGSSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKF5</accession>
    <name>A0A5N6KKF5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_003610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKF5"/>
    <dbReference type="OrthoDB" id="9984693at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033308">
        <property type="entry name" value="PGAP5/Cdc1/Ted1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315">
        <property type="entry name" value="METALLO PHOSPHOESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315:SF1">
        <property type="entry name" value="PROTEIN TED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="247"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8304192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="278" mass="30998" checksum="1EAC4752D1D5AC72" modified="2020-04-22" version="1">MNLDTPVSDKVLQDESYRFLNDIISTSHAVERSALFTLVLTHIPLYKDEGICVDGPFFDFFDGEFENGVKEQNHLSRDASKGMLEGVFGMSGSSEVAGKGMGRLGVVLTGHDHEGCDIYHHINQSSPEEEREWKCNRYSEAKHLVNQSGIPGIREITVRSMMGDFAGNAGLLSLWFDRESWEWKFEFVNCGLGTQHIWWFVHILDFITVIVGIIHGVWSTVLKARLIWGVGGNVRKGGKKGKKVTFETIASESENSREKSVNGNGNREPKGLASGSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKG0</accession>
    <name>A0A5N6KKG0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKG0"/>
    <dbReference type="OrthoDB" id="2420608at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15992">
        <property type="entry name" value="HOLLIDAY JUNCTION RECOGNITION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15992:SF5">
        <property type="entry name" value="HOLLIDAY JUNCTION RECOGNITION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="419" mass="46244" checksum="D927A49C7111D187" modified="2020-04-22" version="1">MKFERHQNRILDQGLNVISWSDAVATIKSLDPRLHKDLAKDASVFDLTDVRPVDVDEDALNLRSSDLEVSGESSDEPELPAHIGSRVQRIAPITVNPAYEFSDEEAEPDVLRSKLREEKSSQLKTPRPSKKARISSSGKSKGGSSGKPRSCKGQLQKKLISEEVDELSFGLEGEAVLFVSSQPRKDKQREPQTSIKREDGQVAVTKMSVIPDLSSKERMSALSNFDDDEFDELSVEWLQSFPSVDQKKPIVESEDVLVAGPPDTAKEANIDLFDINQLPETSPRSALDARKKSRLNKRFSSSAVIPSTSSQTESSPIAAADSRVQWRSQRITDSVDHASIPPTSSYPESSPTPRPKRKYADLDENENSSLTPSRQAKGKAKIPVPSNEDIPLQNEVDGDTTPTRQSPNRKRGGIFNTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMH1</accession>
    <name>A0A5N6KMH1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_004166</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMH1"/>
    <dbReference type="OrthoDB" id="3269380at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000676">
        <property type="entry name" value="C2H2 transcription factor (Sfp1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000322">
        <property type="entry name" value="GDNF-inducible zinc finger protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="261"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="55"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8304827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="393" mass="42707" checksum="752805529254DEA6" modified="2020-04-22" version="1">MPQAGASVGGIQLMRQQQRSQPATPIQKTNQGANDEMDGVEDMEMDDAIGPMDSTPDTPVQNSHNHQPVQAAQQSMFGQQPRPTINLNSTMQHSGLRTSQPPTPAASSFGFQNNPTVSSVNTPTLTAQPMQQSQTFSPETSAPGTPSEMDADFTSMPMNMNMGNRNMNMNNMNFPFNFGGNDLGLDLCIDEPAKRLYSPNGGGFNNQRALQQQFAQFGLGQGQFANNADLMRAYQQQQLMASMNGMGDPTGLMMGEEHKPFRCPVIGCEKAYKNQNGLKYHKTHGHQTQQLHENGDGTFSIVNPETSIPYSGNEGMEREKPYKCDFCGKRYKNLNGLKYHKQHSTPCDPELKLNSHLAAAGLGGLGVPMGGLPGIGEEGMILAGFEILCLELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMH3</accession>
    <name>A0A5N6KMH3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_004162</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMH3"/>
    <dbReference type="OrthoDB" id="370932at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1050.10">
        <property type="entry name" value="At2g23090-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039713">
        <property type="entry name" value="At2g23090-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039438">
        <property type="entry name" value="At2g23090-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026939">
        <property type="entry name" value="ZNF706/At2g23090_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788">
        <property type="entry name" value="OS07G0114300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788:SF1">
        <property type="entry name" value="ZINC-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12907">
        <property type="entry name" value="zf-met2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118359">
        <property type="entry name" value="Expressed protein At2g23090/F21P24.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small EDRK-rich factor-like N-terminal" evidence="2">
        <location>
            <begin position="3"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="At2g23090-like zinc-binding" evidence="3">
        <location>
            <begin position="39"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8304821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="86" mass="9126" checksum="95B1922CAF216B2B" modified="2020-04-22" version="1">MGGGNGAKAASKRARNQKDAEKGAAKSQLKVNESAKDIQCDVCKTTFLKTTRLPALTEHAMNKHSKGPELCFPAFVAQQAVAPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMH9</accession>
    <name>A0A5N6KMH9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_004273</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-A beta-lactamase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMH9"/>
    <dbReference type="OrthoDB" id="428260at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF17">
        <property type="entry name" value="(LOVD), PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="14"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8304956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="369" mass="40814" checksum="33EB9AE82101F6FF" modified="2020-04-22" version="1">MQSFENKIQSAILAGKIPGAVTVARHGSGSYSYSKAHGLHSLRLGASEPLETDGVFWIASCTKLLTAICALQCVERLQFTLDEDVARLLPELKDLEILQGFDPESGAPRLSKATGYITLRQLLTHTSGLAYDKFTPELMKWRVSRGETASLTAGTIEYRYKIPLMFEPGQGFIYSTGLDWAGKMIERANKMTLEQYMQRYIMAPLNLKDLTFHIEKSPSLLSRYVDMAAREGGETPFGTPMNPNGAVVYSEDKVWTQDQTDDCGGIGAYITIPSYQKIVHSITVSDGKLLSSKMNDELFKGQLSDTQLAIVHAALQIDDMRPIIATGLSKDIKLDHALGGMIVEEDIIGRRRKGTMHWGGFPNLFLVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMJ9</accession>
    <name>A0A5N6KMJ9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMJ9"/>
    <dbReference type="OrthoDB" id="3546685at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="227" mass="25759" checksum="92C4AF58C1BAFE49" modified="2020-04-22" version="1">MVKEANFQKTKKESSTQWENRCKLCRGHASSGPRGLCRTCEDNFLNTKAWEDTVENFSDNSDIPPTPPLKDRHITSMREVLATTPPNYHAESSSCPPAQAKDSIHVLRVENSRPQLVNPSPVRQESQKLIYGGMGDSPRDIEIGFPEWQAHLLEVEGTKTEQMFKRWSDNYRVDDSTGGVDGDGEKDQEKEQSPRHSTFYDFWGEILMEDGRSETPKSEDRKPQTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMK3</accession>
    <name>A0A5N6KMK3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">60S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_004187</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMK3"/>
    <dbReference type="OrthoDB" id="407959at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8304851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="15857" checksum="50A3219402039342" modified="2020-04-22" version="1">MAKISRGAPGGKLKMTLGLPVGAVMNCCDNSGARNLYIISVKGIGARLNRLPAGGVGDMVMATVKKGKPELRKKVMPAVIVRQSKPWKRTDGVFLYFEDNAGVSERKLLNYGHVLPVTLVLSCKDAVFFSGFSTSNGGKSWMNGRALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMN2</accession>
    <name>A0A5N6KMN2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMN2"/>
    <dbReference type="OrthoDB" id="2120024at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8305104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="90" mass="10193" checksum="E3A0F3C1B7FEF8B2" modified="2020-04-22" version="1">MRGASISQRRLTSSETPSPTRSFYKTFTRPIAKTLLTATFIYQLTYWGWVKLEKDELKADKLREIKGLEVELEKVSGGAIKGEDVKVKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMN4</accession>
    <name>A0A5N6KMN4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Het-C-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMN4"/>
    <dbReference type="OrthoDB" id="2506204at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010816">
        <property type="entry name" value="Het-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052577">
        <property type="entry name" value="VWA7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905">
        <property type="entry name" value="NG37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905:SF11">
        <property type="entry name" value="TINC (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07217">
        <property type="entry name" value="Het-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024997989" description="Het-C-domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="899"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="741"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="789"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="839"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="862"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="917"/>
            <end position="928"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="928" mass="103485" checksum="7F55087CA514E202" modified="2020-04-22" version="1">MPSFSSSTLLLAFAILVLLAHPAHAFGAGNIASVSKVSGINWRHGDIEDTLLSLIMSRACGGKKFDKMMVARVYFGNWLRDYSQAIDVGTVKYVSAEAIRILLWVLGFMTFGYGTREFEVTAQRLGCYRPEDHIDNPKDYADNLDASQYDHRLRGPVDEEVELAIDPQTGMKNYIANEHAGIMTSALHVRKLFRESIRLGRSYGRSRNKDELYEALRLLGTGLHCLEDYSAHSNYTELALIEMGEHDVFPHVGRNTQIDLPGARYPVYPIITGTFGGVDFLHSVMGEFDDKATQSEIQTLEGTMQEGSEGNSSILKDLLNSVPSGLFGGKDQAGKADELQANASAAQESQEHVSPKDPEAFTQQMQQVAKEIYPIIQWHDEVMQQIREAIEKIPILPNLIENIEEQINIFVFSLLAPFVLPIIGQIKTELNTGSSEVIQSSKDKQLIVFHDDDSTDPTHSMLSKDHFSNILNEAAGKIASAVLKWVVPQLISCWDDERIDPDRTIDRIIHGVFHHPALRHYGDDGASDGRQIMFGVVEEWWHQKDSDEQDEFRRKLSREGVENGENHLEGVHDTGHGCGAPLKMSKQNPGASSNPLANELMGGFTAAMGGNSGSSGFSDHASSGIGKFAGEAVGGGALGGIVSALAGGVGGSLLAGVLGKKGKEEAYSHEGYNSQGNYEQSYTEIGHAGNRYAQAEYTQEQLPDGGRRTEYQQYGQSGDHGVGFEQISEQRPSYGGGYEETNERIYERPDGRIETETWREGETADGRHYHEARHHREERSGSDSEDSGRRRHHRRHHSRRGSGSSRGSDRPQEYIPEREERRERFEEPPRQEYGGYGQQREEYGERERYHEPPRQEYGGYGGERERYEEPQREQGGYGGYGGGEFGEVVGGLAERFGGFGFGGGQREREEEPEDEYRDERREERGWGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMN7</accession>
    <name>A0A5N6KMN7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_004251</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMN7"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024893220" evidence="4">
        <location>
            <begin position="27"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="773"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="801"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="807"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8304932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="873" mass="96427" checksum="B1C5FE7F32536A6A" modified="2020-04-22" version="1">MKSPSQRLILPLVILFWQFIFPISYAQVHEELETSLTAEGSPKPSIQAQPSTAQESHRAPPTKNTAEHELVEKAINSLQRYERSHPRSTSKPPGIVKTLTQYAVASLPRIVQGPPTDGKTPGHQQAPGPVAEAVQLLEQAADVDNSDAIYLLAQMNFYGNYSYPKDYSEAFRRYYQLASLDGNSSAQHMIGFMYATGIGGAVEQDQAKSLLYHTFAAEGGSTRSAMTLAYRHHAGIGMSRNCDLGIKYYKKVADKAIEWHRSGPPGGMAYVQDSYQLAEDDGGVYGEGASFSSAGHNAKSGGPNSDAHAALDDVLEYLDLMSRKGDFKATFSLGRIHYDGQKGLPRNLKSAKWYFTKVAKLYWTRNGKIIDSDKPQLDKIAAKSAGYLGRMYLRGESVDQSYDKAQTWFERGIKNGDSGSQYGMGLMYLHGLGVPKNSVLAQQYFKASADQDFAPAQVNLGAMHLDQGTENDIKVANRYFELAARYGNIEAYYYLAELIDQGVGRDRSCPLATAYYKNVAEKAEPLLTSFAEANSAYEQGDNELALIGYMHAAEQGYEKGQSNVAYILDEQKSKLTVPSWLTLVSTPRPQSLQNAALALLYWTRAAKQANTDALVKMGDYYLYGIGTQADMEKAAACYTAASEFPQSAQALYNLGWMHENGVGLDQDFHLAKRYYDHALETNEEAYLPVTLSLLKLRIRSAWNSFTHGKVNSIIDEPTPRKQWSLAEWISNFLQDDHPYYADYDADDAYGSAHDPMPGGDADGLYDDIIDDGLFESLIIIGLAAALVFLIVYRQQRQEAHRRGEGAAGNAQQNAQPANGEAPNRGLFPQPGDANFNDWVAGGAYSVHVRISDTNSNVKYQYENESWNNVGVEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KN00</accession>
    <name>A0A5N6KN00_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Cyclin-dependent kinases regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_004355</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CKS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KN00"/>
    <dbReference type="OrthoDB" id="440676at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.170.10:FF:000002">
        <property type="entry name" value="Cyclin-dependent kinases regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.170.10">
        <property type="entry name" value="Cyclin-dependent kinase, regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000789">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036858">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01111">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00296">
        <property type="entry name" value="CYCLINKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01084">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55637">
        <property type="entry name" value="Cell cycle regulatory proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00944">
        <property type="entry name" value="CKS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00945">
        <property type="entry name" value="CKS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00068939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU311113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8305052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="116" mass="14044" checksum="AB1E9F54B5AB88C3" modified="2020-04-22" version="1">MAEIDYTRRNKYARPLSEAEKERLDEFIDAIHYSARYSDDQYEYRHVQLPKAMLKVIPKEYHDPQTGTLKLLWEEEWRALGITQSLGWEHYEVHEPEPHILLFKRSINYQPPTQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KN01</accession>
    <name>A0A5N6KN01_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Stress-associated endoplasmic reticulum protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_004386</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Interacts with target proteins during translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation and facilitate correct glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the RAMP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KN01"/>
    <dbReference type="OrthoDB" id="16679at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010580">
        <property type="entry name" value="ER_stress-assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06624">
        <property type="entry name" value="RAMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8305085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="180" mass="20187" checksum="A7FE88BEDE3E969C" modified="2020-04-22" version="1">MVEQRLFSQIGTTEGLYEQHVAFSKALREGGGEVKKSEDAVNKAAKFVEGTKYGDREEKGDVIYCTFALTDNFLTDIHIINSLSSYIRVIRVRKKTHIDNSLFAIVKMVQTPAQRKANLKFAATNESKQGKSEAQLHKKELKKQKSPISKGWLYLLAFILIGGLVVDVLFRIISYFGGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KN09</accession>
    <name>A0A5N6KN09_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Clathrin/coatomer adaptor adaptin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_004388</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KN09"/>
    <dbReference type="OrthoDB" id="10264595at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030123">
        <property type="term" value="C:AP-3 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017105">
        <property type="entry name" value="AP3_complex_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22781:SF12">
        <property type="entry name" value="AP-3 COMPLEX SUBUNIT DELTA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22781">
        <property type="entry name" value="DELTA ADAPTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="8">
        <location>
            <begin position="2"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="385"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="596"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="638"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="404"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="510"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="666"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8305088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="675" mass="74342" checksum="82DF348868C59D1B" modified="2020-04-22" version="1">MDCIDSADISIRLRALDLVVGMVSSDNLMSIVGRLMRQLRSSPLAPTNNSNSRYVGHIEPEADSDDEAPEVAIKSDRGSSQDLLLPDDYKVDVITRILEMCSMNNYANLVDFDWYIDILIQLVRSAPVTNPSNHESDEYSENDISEKIGDELRNVAVKVKAVRSQAARAAESILVLAFNDTTSQVSSGNSALRPISWIIGEYASYLESPENTMAALLHIAKVSTSAEGLIVYLQALPKVFSVIADDEHSHWTAERKTMMSLLMARIINALEPLAMHPDLEVQERAVEFSELLKLAAEATTGQEPSSESVQQDAPLLLTQALPSLFRGQELNSVAASAQKNVPVPSNLDLDQPINPNLHNLLRNVDTISFDEPENDEFEVYYHQKPEPTSISSNEPAISRLGGSPDQSAQSYQQGGEESYLDPDIVARRKAERLERNRDDPFYIAPNDGGTSGTSTPLHTILQSNNGPDLDIDAIPIMQLDLGKTSLSIGNNKKPSKKPRHRIQVAADETLNLSGNSTPANDSENSADGPIKSRITKGKQSLLQVDSSHIGQFSLEGDDTSGIDFERQQREEAEMVKAMKEVERLRLEMQRANERIQAAQDVPPEGTVVKRKTKKKAKPVEGEEAKTIVKKQKKVKKAVVDEGEGDPSVAPTTTDIVKPKKKKKKPKVEEKIMEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JLL8</accession>
    <name>A0A5N6JLL8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_010106</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IFI6/IFI27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000031">
        <property type="protein sequence ID" value="KAB8287400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JLL8"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009311">
        <property type="entry name" value="IFI6/IFI27-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038213">
        <property type="entry name" value="IFI6/IFI27-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16932">
        <property type="entry name" value="INTERFERON ALPHA-INDUCIBLE PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16932:SF18">
        <property type="entry name" value="INTERFERON, ALPHA-INDUCIBLE PROTEIN 27-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06140">
        <property type="entry name" value="Ifi-6-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8287400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="121" mass="12266" checksum="7281FE7760FD7BAF" modified="2020-04-22" version="1">MLSFRKKGGPVTIASIAVVPILGAVGFSAVGPVARSAAAAWQSSIGLVEAGSFFALCQSIAMGGAAIGGIVGAGLGGAGILAVATSLNELDGVDFDTFELKKRFQEAWKREIRGDQRTQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JNK4</accession>
    <name>A0A5N6JNK4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome c oxidase assembly protein CtaG/Cox11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_010219</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000025">
        <property type="protein sequence ID" value="KAB8288217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JNK4"/>
    <dbReference type="OrthoDB" id="1704689at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.370.10:FF:000001">
        <property type="entry name" value="COX11 cytochrome c oxidase assembly homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.370.10">
        <property type="entry name" value="Ctag/Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00155">
        <property type="entry name" value="CtaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023471">
        <property type="entry name" value="CtaG/Cox11_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007533">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_CtaG"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003465">
        <property type="entry name" value="PRK05089.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21320:SF3">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21320">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04442">
        <property type="entry name" value="CtaG_Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110111">
        <property type="entry name" value="Ctag/Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="205"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="207"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8288217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="26460" checksum="165F2094E6D7A9EE" modified="2020-04-22" version="1">MEQLRAPFSQKNSSTMYYTLSIILGTVAFSYGSVPMYKMICQTTGWGGQPIKAPGHGGGAAGEDPSERLRPVTSAKRIRVTFNGSVSDVLPWKFTPQQREVRVLPGETALAFYTATNKSDEDIIGVATYSVTPGQVAPYFSKIQCFCFEEQRLNAGETVDMPVFFYIDPDFVNDPNMKGIEQVTLSYTFFKARYDKNGHLKPMPAGISSSSSSSISSGFGSGSPSSSSSSSSSIVRSPVSQSVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JPM3</accession>
    <name>A0A5N6JPM3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_010946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000017">
        <property type="protein sequence ID" value="KAB8290518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JPM3"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8290518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="70" mass="8592" checksum="DA32552FCC7CD9E8" modified="2020-04-22" version="1">MMKLGGWFKEKERKKERKNERTKGRKDERTKGRKEERHKSKDQSIPTYKRKLSFCPEYLVNLKRLVLIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JPN9</accession>
    <name>A0A5N6JPN9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_010947</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000017">
        <property type="protein sequence ID" value="KAB8290522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JPN9"/>
    <dbReference type="OrthoDB" id="437889at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.555.10:FF:000041">
        <property type="entry name" value="Rho GTPase activator (Rgd1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF136">
        <property type="entry name" value="RHO GTPASE ACTIVATOR (RGD1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="461"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="298"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="367"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="398"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8290522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="654" mass="71469" checksum="A56ECCE61E0307AB" modified="2020-04-22" version="1">MSLGGDTALDTASSPNAIGNGNGNGNNIDTAGRPATPEDVTTKAVRDVTSSEIGISTLLNRLKQRIRIFSQETYSQTRASAWFVSAVFGVSLHQMHDDLMEMASNMEKSRKHWKTTGLTAEQRAADTEAAMRKSKVKYDALADEYDRARTGDRQSGKIFGLKGPKSAAQHEEDLLRKVQAADADYASKVQAAQTQRTELWSRARPEAVKALEDLIQECDSALTLQMQKFASFNEKLLLSNGLNISPIRAKEQGTSNRSLREAVHAIDNVKDLSNYISSFAGKVPSRVTEIKYERNTVLQPSQNIGQRQSDPNALNSRQGSGIPPQPSHQVHMSMSQSFQSTIPQTHQHERSFSHGPSLSHHIAAPVTSPTNQISNSPDFNNWPPRADGPPQISTLPFQPQPQSEPIPQQIPPNPIAHAPAPSGPPSGSPLGPPPGAAFSPGPVPNSGNNTHLAPLKPVFGLSLEELFERDGSAVPMIVYQCIQAVDLFGLEVEGIYRLSGTASHIMKIKAMFDNDASKVDFRNPESFFHDVNSVAGLLKQFFRELPDPLLTVEQYPAFIEAAKHDDEIVRRDSLHAIINGLPDPNYATLRALTLHLNRVQESSASNRMNASNLAIVFGPTLMGANTGPNIQDAGWQVRVIHTILDNTYQIFDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JQ04</accession>
    <name>A0A5N6JQ04_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000016">
        <property type="protein sequence ID" value="KAB8290720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JQ04"/>
    <dbReference type="OrthoDB" id="3365616at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22952">
        <property type="entry name" value="ART10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8290720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="24502" checksum="D3AD3DA199635777" modified="2020-04-22" version="1">MPLRILLRKTNTSPEHVFLVSLQVNLIGTTEVKASDVIRCETSTWVVMSLTGLSIPIGSPNDPIGTETAIDSKLWDAIPLPNTVAPSFVTCNLARGYELEARIGLGYGYPGEIQAQTINIPLRFKIDIFSGIEPPAALLDAMTAQPPIPARPPVSMAPPPFDPAFPPQVGAPGAPDLDDAPPSYEDALAEDITQANGASRPAYSGVTNENAPGIDEKGGLSTGHPKGEASRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JRS0</accession>
    <name>A0A5N6JRS0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LisH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_008346</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000016">
        <property type="protein sequence ID" value="KAB8290707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JRS0"/>
    <dbReference type="OrthoDB" id="5600002at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12610:SF12">
        <property type="entry name" value="SEQUENCE-SPECIFIC SINGLE-STRANDED DNA-BINDING PROTEIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12610">
        <property type="entry name" value="SINGLE STRANDED DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="75"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="180"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="376"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="482"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="707"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="500"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="560"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="587"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="610"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="631"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8290707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="731" mass="77621" checksum="87193BDF9B8B8701" modified="2020-04-22" version="1">MNNVTMSGMPNMGGPVGGGIPMMNNGVAGGAARHSTSNDNNRSQLNTYIYEYFLKSGMFDCARTLLNHEQINVVKDSPGRNDAEDGEDSKDDIDSKRPSDLPLPNLPKECPESCFLYEWFCLFWDMFNAQRGKGDARNVLSYVSHTQQSRQKAEQHQAQLRNINPMHAGAAYGRMGPGGMMGPNDLARKAMMNGRGGGPSAQQLQQMQQMQMQKQQAMQREPSDGNHPQRAQSPGSAENAPSPSKRPRLDGPAFNGQQGGMAPNGRGQSTGIPAQQYPGFQGQNPTQKNLQAYQANLSQHQQKQMPNAAAGGPPNQGSPMMTQGADSNAIAAYGYGGEMGQNGARAGPGGQQAGPGNHALQDYQMQLMLLEQQNKKRLMQARQEQDAIRPDGQGGAGGPGMGPNFQQGTSPQSGPRSVNSPNPSEQMKRGTPHMNNPGIPSPLPEGQNRGSPSTMNFNMGQGGQMDAGMAPQFYKMEGMNNNMMANGMRPPSSHPTFNPQGMSQQQMMMARQQAGNWQNGPNGGAPMVANPSQGPPQAMGTPQQRNMPPPAAPANANANGRTQPPSPQGSTAAPPTPQQSNKANPKKKNETKETKTKKGSAANLAAGATPSADPSQDAATPAPATPITPVHTKTFNNGSNPNGAVQPVNGQPMASAPNAGVSSSQADPMSFPMNDPQFDMLEFQNPMGGNTDVLTDFDFDSFLNDSNTGADDNYNFDPSGFLGDNEISETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JS35</accession>
    <name>A0A5N6JS35_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Plasma membrane channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_010881</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000017">
        <property type="protein sequence ID" value="KAB8290450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JS35"/>
    <dbReference type="OrthoDB" id="296386at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049456">
        <property type="entry name" value="Anoctamin_N_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20877">
        <property type="entry name" value="Anoctamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="611"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin alpha-beta plait" evidence="8">
        <location>
            <begin position="23"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="7">
        <location>
            <begin position="181"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="672"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="683"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8290450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="740" mass="84065" checksum="CEBC4667D6417C7A" modified="2020-04-22" version="1">MASLQSISEPNPTLGNALNTNYEVDYVIDYRFATTNKVQAEEQFVKLIEALNDVGLMTEVRHGDNCALLIFIKTASSRHLRSEVYRSRVQDWLYGVRTAAPEKNMQEALSAEPMTEAERLRLVYLLITKPRNEGGAGITPKKGEWKGVESIFPLHDHAFNKAWIKEITSKYLLTTKDLEDIKDRFGEKIGFYFAFLQSYFMFLIFPAAFGFCAWVLFGQYSPIYAVVNGLWSIVYTEYWKKQETDLAVQWGVRGVSKIQHKRPDFKHEREIKDPVTGEQIKFYSPVKRLSRQLLQVPFALCATVILGSLIATCFAIEIFISEVYHGPFKAYLTFLPTVILTVFMPTLTVLLTGFASKLTDLENYETVDSHDAAMVQKIFVLNFITSYMPIFLTAFVYVPFAQVIVPHLDIFQMAVRPFAENDEQMTVPKAGFQINPDRLKSQVIYFTVTAQIVNFALEVIVPYVKRSLFRKYKEVQADRAAKRGGSSTPDNDHPEEVAFLTRVRNEAELGIYDVTTDFREMIVQFGYLSLFSVVWPLTGLSFLVNNWIELRGDAVKIALETQRPVPWRADSIGPWLDALGFLSWLGSLSTAALVYLFSGDGFGPDGTPSKMTGWGLLLTMFFSEHIYLALRRAIRLALSKIDSPGLQRERRERFAVRKQYLQETLSQEAAEKAAQGGITQGEKISRSTLEEEARDSTLRGHGTAEERFWARQRGQGETIAMGRSFINKAAPEQVESKKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JS40</accession>
    <name>A0A5N6JS40_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JS40"/>
    <dbReference type="OrthoDB" id="3439480at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8291693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="346" mass="41173" checksum="EF537AD1F46689F2" modified="2020-04-22" version="1">MCVTHIYTDCYPKRTVEFHQTILCPNAKDGVSCPAHIANKHLPRTLDSNDDRSSKDYIDQGLKVPATSKSSPHKSTTTTTYRYSQGDKKDKPPGREPRLRLVRKKSALASAPTPRRKHPKEHILIVDAPDSPQESKSLPQYSPDSPAIEVFHSKTLLMADRPHRQESPSPRRNSNRGLNPARAVVVEQQHRDKREHSKERERTLHNLPIILAPEPPSRSPSRERELADMRIRREEEERERGRQREYEREREKSFDMANEAKWEQEREMEEMRKAAEELERERIRRENSEDEKRREAEYKKFWEEREREREAEKEVERQRAREREDTLLRERERGETKKRRRTQNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JU63</accession>
    <name>A0A5N6JU63_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CBM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_008102</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JU63"/>
    <dbReference type="OrthoDB" id="3564179at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="CBM1" evidence="3">
        <location>
            <begin position="154"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="54"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8292365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="193" mass="19463" checksum="67D9AD5B25021D43" modified="2020-04-22" version="1">MATNIYRPGGHFHVRAYNGSEPSFPSGTGPSSGFARPTGKPHHVTSKKPCKTKASSAAASSQAAATSVPASDTVVVTVTPSATSAPSATTSPVVPTTLKSSDVDTSSVAPATSSKAPASSLPPYPTTFATSASSTVASTGFASGTGGAAYPSSTTVAAYYQCGGINWTGPTTCVEGTHCQYQNPFYYQCIYQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JU79</accession>
    <name>A0A5N6JU79_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleotidyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009998</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JU79"/>
    <dbReference type="OrthoDB" id="4708870at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8291314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="49079" checksum="1043DD2EAEE996E5" modified="2020-04-22" version="1">MTQEVYDKALEQNQAILRKFYSRVASAIEGPGKTTYGDVDILVALPLKDAFPPQERVPDTLQKALHASACVQYKGNPTINFAVPWPENSTTSATNMLGEDGEDVAESTDVSSAEWYVQVDIYICRDEHEFDWELFHYAHGDLCNIIGTIVKRFGLTINNRALFIRIPEIELADKKKSMVFLTDNPAKILDFLGLDQEKWWKRFDTQQEMFEYAATCRMFWVRNVVGGEAERDVIGIKVEGCQEGGEEGKKRLKYNDRQRATRPIYKAWVDEFIPQCREQASYSDIKITREEIRDEAFKKFGIKEEYETKRHDWNLAKHLVELVNDGIKGNIPLDGVDGQMRSAATKVLKGIIMEGEPYEGGLPEAAIKDANGFYNLELVKHFVRENWGNAGSIGMARQQTRAREAMRAKAEKRAKAEMAKCEQDSGLQKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JU86</accession>
    <name>A0A5N6JU86_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_006589</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JU86"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8291796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="198" mass="22440" checksum="135BF1327E990A47" modified="2020-04-22" version="1">MFVKAHDISRAESQTVLRLLHYFKVNRELENKDWVRAGPHVDWSFLTLLFQNLGQAGLEICPGREVSGDFGWGDEWTKIHPGEGEVVCNIGDCLMWWSGDRFRSTFHRVVTPRARTNGTDGDGDEDDGDGDGDGYGDEAWGDRYSLAFFNNPCEDVVIRGKEGEMTGREFTERAMGRNFSGVRENLRQKEREMGKVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JU90</accession>
    <name>A0A5N6JU90_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NTF2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_010098</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JU90"/>
    <dbReference type="OrthoDB" id="6507044at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045875">
        <property type="entry name" value="NTF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12612">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="2">
        <location>
            <begin position="7"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="NTF2" evidence="2">
        <location>
            <begin position="62"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU369002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8291425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="99" mass="11283" checksum="1D168AA4DAC48A27" modified="2020-04-22" version="1">MANFQDVAKQFTEFYYNQFDADRNQLATLYRENSMLTFESASVLGAGAIVQKLGSLPFEKPLLVDEEQRPMNYSQAFQLMPDGAGSYFIFNDVFKLVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JU96</accession>
    <name>A0A5N6JU96_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal eL28/Mak16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000014">
        <property type="protein sequence ID" value="KAB8291806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JU96"/>
    <dbReference type="OrthoDB" id="338850at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="1">
        <location>
            <begin position="53"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8291806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="111" mass="13092" checksum="B075B6950A8882FB" modified="2020-04-22" version="1">MRSPIFKSFSNNHNTRYLTTYRYNDNDNDNDTNKNPFNSNHFTMSQYVSADFIWEVTRSQNAFLVKRTTGGGSTFSRDPLNLTNKHSTPERMGANWTIVCWFRQRQGTRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JVU3</accession>
    <name>A0A5N6JVU3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8292933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JVU3"/>
    <dbReference type="OrthoDB" id="3937708at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025017291" evidence="1">
        <location>
            <begin position="25"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8292933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="406" mass="42930" checksum="409711BC3AA9EF6D" modified="2020-04-22" version="1">MLSPISHVLYTFAILASIFTYAEADCASYGIDFQNGASYFINNLDTSSFTAVTQFVGCSGTADVILVGPDENSWLCSDISTRPDNANQLSICPLLKSEMYSGSWTIVILGNNGNSSSFAAQRTFDLLVGPQSTVTFTPTVNVTSIVTPSTTLPTTITETDPTTLSALTITAPSATASNIVTITPEKVTTTVTTTSTRTVTSRKYTFPIITVTKTASCSVPTKAATRDPYPNQHYLALAQSVTSDSSVKRTAIPAPAAAQITPAPRANINNRDVNVDIANVLGRRAVGRLLEKKLKKRAPDVPTLTITDTTTSDWKTSTVTTTTTTTTFYSTATATQFTTITPAPVTVRTGVTTSTITAPTPTTTKTTQTQTTRTITTTITYNITVTKTTTPASVIATCTSKGGVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW76</accession>
    <name>A0A5N6JW76_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_007530</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW76"/>
    <dbReference type="OrthoDB" id="1049195at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000145">
        <property type="entry name" value="Putative RNP domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000232">
        <property type="entry name" value="RNA-binding domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000280">
        <property type="entry name" value="RNA-binding domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF3">
        <property type="entry name" value="FI21236P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="100"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="226"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="391"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8293187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="529" mass="56409" checksum="154FA4C85D38BD2A" modified="2020-04-22" version="1">MADDSYRPQRERSRSPRRQRSRSPGRTQRRRSYSPRSRSRSRDEHRRNDRRSRSPMSGAAGVGGSGGSAYGGQPHRTYEERAAAREQMMSSLRESSQQDRRVYVGNLSYDVKWHHLKDFMRSAGEVLFADVLLLPNGMSKVGAYTIVEYATREQAQQAVNTLSNQNLMGRLVYVREDREAEPRFTGTPAGGRGGYEGNGPPGGRGGFGGGFGGGMGPGGGAGGGGRQIYVSNLPYTVGWQDLKDLFRGAARNGAVVRADVHVGPDGRPKGSGIVAFESPDDARNAIQQFNGYDWQGRPLEVREDRFAGAQGFGGPRGGFGGGRGGFGGGFGGRGGFGGGRGGFGGGFGGGRGGFGGGYAGGAGGFDGGAGAPAAAPNPFTDYATAGTERSEIIFVRNLPWSTSNEDLVELFTTIGKVEQAEIQYEPNGRSRGTGVVRFDSVENADTAIEKFSGYQYGGRPLGLSFSLTSHKIKLCETESVRTNGTKLLRQISNMLQHTLFFLLSSISLCVLKTSNPPKSSDVEDSTLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXZ8</accession>
    <name>A0A5N6JXZ8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_009481</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXZ8"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="239"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="239"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8294021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="37598" checksum="9D17702DFA980384" modified="2020-04-22" version="1">MDSLRRIPWPYYLMHSQGLKMHNASSDHTYNNKNSPHQSSHQILARRTILDEWTTDYIIQPLHFPRRLIGCPRIRSGAKRFQRCSASYAEKGMSALLTTFKRSQVPENPAALPDTSLAQQSSKNVSNLPDLEDFSAFFTFPAHSPPTYHPMSKRVDRQEIDPNASFSLSHNHPSTTDTPTLKSEIPSPASARNKRRATGPATASNTSAFNMQSSSSMAGPSSSGLDDPNMPSSMAPPAKKSRTNTPWTPAEEQRLKNMRDAGNSWADIAKTFPARTEGSVKKHWYKDMHYAEFAEDEALLAAIKDYEVNKWKAIGQKVGKPAKACEQYAKDNFGGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYA1</accession>
    <name>A0A5N6JYA1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYA1"/>
    <dbReference type="OrthoDB" id="3497519at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8294143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="151" mass="17244" checksum="3F6D5F1EB2AD731E" modified="2020-04-22" version="1">MRLFLANLDLEAETKDTDTEYLKYWINIFWKMEIRKGKHNDLLIYHKMPYGFTWDRDGDALFDACLHYSDHFVDAPFGQGIARRAQAVGPGKLHERQKSMHDALTIGNPIRVGPENILGDRFPRRTGVERTPSPPSPPLPSRPIIGGVESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYA4</accession>
    <name>A0A5N6JYA4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYA4"/>
    <dbReference type="OrthoDB" id="3497519at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8294142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="104" mass="11403" checksum="3EC25DE89E514145" modified="2020-04-22" version="1">MPYGFTWDRDGDALFDACLHYSDHFVDAPFGQGIARRAQAVGPGKLHERQKSMHDALTIGNPIRVGPENILGDRFPRRTGVERTPSPPSPPLPSRPIIGGVESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYA5</accession>
    <name>A0A5N6JYA5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_009577</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYA5"/>
    <dbReference type="OrthoDB" id="6910977at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002724">
        <property type="entry name" value="Similar to transcription factor Zn, C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="399"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="431"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="462"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="358"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8294131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="516" mass="57811" checksum="DCAFE1AE81E885F1" modified="2020-04-22" version="1">MVLTPPVTSVMLPTKTAAILVTSYSIFDLLLLDITHTTSDSFRFIFATVQVLVLQLSPQFLYEISHHIPGSYYTSPSRDLPVPSTISHYSSHTSSPQPVHWLFVLPSYLYFSLTFFSNLINNMELTPQSTRSPTPPLSFSGNSQPLFEYPSPAQSESRYISADSIRGLGLYSCSMSGSPPAMEHQDAGSESGGPSYVAINTWADSRDTPRSSMSTPNILSAEYDPFASYNTAVSAPFTTDIYTTSQTAEIPILPASPLPSSNTSHRSSLSSVPPSEVFTQAGSMPSYTPRIKMEDHSEYAPSGDSFTLGSPHNNHTSFVSGANTYPGTLETSYYDQSLWAQKVEYASTDLPPFSALQIPTYDRRSESQDRSLSQDLRRPSVVARTRGPRKLTTKEDANFQCRVKGCGKLFGRSYNYKAHMETHDADREYPFPCTVDKCTKKFVRKTDLQRHNQSVHMKQRNHKCDYCSRFFARKDTLRRHMEDGCSKRFDIETVDFRPQNYAIDNNPLHQLKGSIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JYA7</accession>
    <name>A0A5N6JYA7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_009574</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JYA7"/>
    <dbReference type="OrthoDB" id="1716816at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02979">
        <property type="entry name" value="PHOX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF7">
        <property type="entry name" value="P-HYDROXYBENZOATE-M-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="6">
        <location>
            <begin position="99"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8294126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="35087" checksum="4F8F9A3212D7B4FF" modified="2020-04-22" version="1">MNTAFLDAQNLAWKIHHVESGFAHRSLLHSYEAERKKVAENLLDFDAKYAALFSQKAPAAKDVEAATQRGAENTKVAEEGNEFIKTFKESCEFTSGYGVAYNPNSLNWSSSHPAQSSVINPKGNKLRTGRILTNSNVTRVTDANVVHLEQEIPVNGSFRVYVFAGKPATTKQALDDFAQNLTKKGSFFSTYLRSDIDQVSYHERHNPHSHFFTFCTIFAEKRQNIEIARDVPKTLARYADHVYADDIWDRIVPDSKASSHSKMGLDEEKGGVVVVRPDGYVGIVVGLEKGSATVDALNEYFGAFCSKKLGESKALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K011</accession>
    <name>A0A5N6K011_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8294972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K011"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8294972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="73" mass="8632" checksum="EDC00EAFD305A788" modified="2020-04-22" version="1">MFITTSNWVKVHFISWLLNYWHQYLDFSDKACFKIPEPNHTQNNAQCSDVERIGLEVFLKSICSLRRNPSTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K012</accession>
    <name>A0A5N6K012_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arf-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_007048</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K012"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000081">
        <property type="entry name" value="GTPase activating protein for Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051718">
        <property type="entry name" value="ARF_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705:SF7">
        <property type="entry name" value="ACTIVATING PROTEIN FOR ARF, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G09120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="4">
        <location>
            <begin position="10"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="88"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="214"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="418"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="501"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="597"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="666"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="460"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="219"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="267"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="597"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8295113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="686" mass="76773" checksum="B38DEE6792CCE44B" modified="2020-04-22" version="1">MFAPTVKHEIQLGIFLCMRCAALHRKLGTHITKVKSLSMDSWSKDQVDHMKKVGNVASNRIYNPQNTRPPIPIDADEADSAMERFIRQKYSNKAPTQKRNNTGSSDERPPPPPKNGVKFGFRSASSIFPLSSKARKDNDDARAEFHDYNQASSPPRRNKHSRIFGTSLDATDDLESKMAKLRELGFMDDKRNTAVLKGLSGNLEKSIETLVRLGEGGSSARTGSSINSSGPRTPASPPGLSFERPQATSPAATSISTNPFDRLDNPSFPQVQSSHSTGSMAQTQNQMGGNPYQSAPSTNPFGLMPSQSQLNLNQAFQNMSVSSPQPLFPHHTGGVPGPQPQPVQQLYQQSMTPPVPSIPQHHYPQVIYENPGQQSQLQQVDRSTNPFMQQAPPAVNTNLQSNPFMQQSVMNQTLFSSPVAQTPQQQYSTGSYNMGAQNPSPQQMNPFFNQVNMQQPQQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQQQQPQQYGYQQQPQNQYQPQTQIQQPQYQQPQAQTQQLQYQHPQTQTQQPQYQQPQAQAQQPQYDQYLQQTQPTMPQQAGRLVDKRSILDLYNYPQLAPTQIQQQQQQPDSIQHQAPPQAVEMPPTNGHMPGGSNNPFMSNVAAIPNGGTNAANGSGRQISRESMMIEAGGWQNGRHSPDAWGQISGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1I0</accession>
    <name>A0A5N6K1I0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1I0"/>
    <dbReference type="OrthoDB" id="432234at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="212" mass="23195" checksum="56FE6A65A4A88BD8" modified="2020-04-22" version="1">MPFGRAAFPAPSSFTRGYLAQRWRAHPHFIFRNANAPTQELRYSSIANAMLGRAIKAKATEPQAPTPKDDAKKKAITHNNMTRNGNIQDSLKPKPKSSQAIGGFIQPLRPASANGKTPPKESQSIVALSTTSSHLSSLLSRDDSFKDTPNSSFDLVQFDSDDLSDDDNIDFDISYALPTYPLSTNASMPAPPKPIRPTIPLSPFTERKAERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1I5</accession>
    <name>A0A5N6K1I5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_008826</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1I5"/>
    <dbReference type="OrthoDB" id="8093034at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12614">
        <property type="entry name" value="RRM1_PUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12619">
        <property type="entry name" value="RRM2_PUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12622">
        <property type="entry name" value="RRM3_PUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000117">
        <property type="entry name" value="Nuclear and cytoplasmic polyadenylated RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000224">
        <property type="entry name" value="Nuclear and cytoplasmic polyadenylated RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000134">
        <property type="entry name" value="Nuclear and cytoplasmic polyadenylated rna-binding pub1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038:SF1">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="263"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="353"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="479"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="181"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="550"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="561"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="636"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="654"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8296013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="675" mass="74001" checksum="7298987A4D7BAD9A" modified="2020-04-22" version="1">MNVAPHATLFIRPSLFNLLQQFARTSNLPYFLTPPHFLPSSAIFSLSVQKILQRRRRLFFSLFLNLLSNNRRLDFRVVFVSSLFLSTFFVYSIIHSHNKGYTLTCCYLSFSGPFRKLSIEFSSLLRFLSFKLHKNINQRIFATQLFFVPCVINLFTIIPAQFFYFDPTSIYFIRADNGPTPASAQLPPPPQTSAGAPGYENGHNSQGNPSHMPPPPLPPVIIPQNTNPIPTAITSPMGENGGVMSPDSAGGFVRRAAPEPNKRALYVGGLDPRVTEDVLRQIFETTGHVQNVKIIPDKNSKGFNYGFVEYDDPGAAERAMQTLNGRRVHQAEIRVNWAYQSNTSNKEDTSNHFHIFVGDLSNEVNDEVLLQAFSAFGSVSEARVMWDMKTGRSRGYGFAAFRERQDAEKALSSMDGEWLGSRAIRCNWANQKGQPSISQQQAMSAMGMTPTTPFGHHHFPTHGVQSYDMIVQQTPQWQTTCYVGNLTPYTTQNDLVPLFQNFGYVVETRFQADRGFAFVKMDSHENAALAICQLSGYNVNGRPLKCSWGKDKAPTSAGFDGSQQSYSPQAGPTPGGFPGTPNAYFPQYGGMPPQAGPQSAGPMANQQSPGQFAGQQGGYGGPPAQSPAQYGNQPMGYGGPASAGGYGRGAQPTPAAQWSAPATQSYGNGFGGYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1M3</accession>
    <name>A0A5N6K1M3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_008864</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1M3"/>
    <dbReference type="OrthoDB" id="5363290at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8296057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="130" mass="15083" checksum="F7ED6916D9119506" modified="2020-04-22" version="1">MPSGLILLMRFCGRVARREWCCFGVGRRGLGGRGERRVGVEVREFRRKGRESRGDEIGSGVHYRLRYCHLVDLIPGIQTDVSNRLTNEIYHHSRNPISKAEIRYLRNGQKLLIWEDGRDYDHGDKTVMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1M8</accession>
    <name>A0A5N6K1M8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1M8"/>
    <dbReference type="OrthoDB" id="5361354at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="251" mass="27835" checksum="3631815FE5EAEE93" modified="2020-04-22" version="1">MNLLPLQTSQSHPYLLHTKSHTNPPPSSTSQAQILNVALINPPTNSNHSPKNYSTPVIESSISRTNDSIRLSQKSSQVQNHRLSKDRDLIYYDPTSRPSARTRSGSVQGRAVDFDRPRESPFSNSNAILGGSSGESFSSASSVSTGGSRDSSREGRGRGRSESVGEMEANDGDRNHRRGRSIVGETIVEVLTPMTSRGERFDASHMLMDMSRGNCIYYVYTMMVVWDIKGSAYTYERRRDPEILELGLYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1P8</accession>
    <name>A0A5N6K1P8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1P8"/>
    <dbReference type="OrthoDB" id="4146887at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39609:SF1">
        <property type="entry name" value="RFEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39609">
        <property type="entry name" value="RFEG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="92" mass="10263" checksum="DCDEDFAC50521A79" modified="2020-04-22" version="1">MSRRDDRDRASRSQPQASYSSAGRTGQFVIDAEGIDREVITADICRYLGNDALVKPGDVEVSHFESLQALCRWETNGSISRTQERNNLSLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1T3</accession>
    <name>A0A5N6K1T3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor RfeG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1T3"/>
    <dbReference type="OrthoDB" id="4146887at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39609:SF1">
        <property type="entry name" value="RFEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39609">
        <property type="entry name" value="RFEG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="38021" checksum="8E6203FD4C798F0F" modified="2020-04-22" version="1">MSRRDDRDRASRSQPQASYSSAGRTGQFVIDAEGIDREVITADICRYLGNDALVKPGDVEDPRTKQLKPVYVITAYRNLTNAMIHDLKQASADWRAERLARSSAQYPTNVVDYRSSNALDQSIARMDATQQPRPAAQQGMYNSPSAAVPSSQSYQPSGQGYSAGYSQPTSYQNDGYTQPPSQQYAPSAQGYPTQDTRSYVHGSNYAVEPAGRGGSVPQSVPRTQAVPYPPTTSYQAPAPQYYSQSGPPPSTSAYAAHAPTDPYYSRGNYETTPEIYDTRAYPETSDYQMQDAGYTEPGSYQETVSYSQPMPSGRSGTATSSSSQRTRDRDSRDDRDRHHQRRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K208</accession>
    <name>A0A5N6K208_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TFIIS N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_008940</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IWS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K208"/>
    <dbReference type="OrthoDB" id="21124at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.930.10:FF:000003">
        <property type="entry name" value="Putative Transcription factor IWS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051037">
        <property type="entry name" value="RNAPII_TF_IWS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46010">
        <property type="entry name" value="PROTEIN IWS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46010:SF1">
        <property type="entry name" value="PROTEIN IWS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="8">
        <location>
            <begin position="50"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="191"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8296152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="236" mass="26484" checksum="635FA7A04D03BDDA" modified="2020-04-22" version="1">MEEACQADNAARDANLPATRKLEMLPEVVALLNRNTIQHSIVDPDTNFLQSVKFFLEPLNDGSLPAYNIQRDLFQALARLPIEKEALLSSGIGKVVLYYTKSKRPEIGIKRIAERLLGEWSRPILKRSDDYKKRKVATKEFDHQAAQLAIRPSGSQSSQLPSQRTGLTARELERQRLLAPKIISNRARMETSNTSYSIAPRSNFDPSRGLDPNSRPIGAGGVEAFRKMTTKQGKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K215</accession>
    <name>A0A5N6K215_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_008947</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K215"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052392">
        <property type="entry name" value="Kelch-BTB_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46375:SF3">
        <property type="entry name" value="KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46375">
        <property type="entry name" value="KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8296161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="349" mass="37446" checksum="990686F5E48E53C4" modified="2020-04-22" version="1">MGGEFFLVMNRFSESIFGHRILNRLQFPIQPANLAQVPGNPSPHPLYPRQEHSTVYIYPYIYILGGVIPSSTNSTTDPFPTTSLVQRFSLLTQTWSFAAPLPLPLNHLNAGVINGRIYILGGLTPSSGIWVASRATFVYDPPSDTWSRLNDIPAGLEVGAAAVAVRGNTMYLAGGLTSVDISQSSQPTVALFTAWNAGRQIFTSLPVMPAPRDHAGVGFLLDPGALYVLGGRAFGHNNVVDTTFVFEFRTGEWKEVANLPTARGGVASAMINNSIFVIGGEGNPAPNSNGVFSQNEGYDTATDTWKEYAPMDVPRHGTSAVAIGNRIYIPGGGVAEGVAPTSYFSYFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K253</accession>
    <name>A0A5N6K253_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Histone-binding protein RBBP4 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_009023</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K253"/>
    <dbReference type="OrthoDB" id="2161379at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051972">
        <property type="entry name" value="Glutamate-rich_WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45903">
        <property type="entry name" value="GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45903:SF1">
        <property type="entry name" value="GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="45"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8296247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="15260" checksum="E8D01E7C4B653B81" modified="2020-04-22" version="1">MSWSHQTSHLLASGADDGVWAVWDLRNWKPTNNNSPSKPTPVASFNFHKEQITSVEWHPTDDSIVAVAAGDDTLTLWDLAVELDDEESKDTGGVNDVPPQLLFVHYMAKVKEAHWHPQIPGALVGTGENFNVFKTISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3R1</accession>
    <name>A0A5N6K3R1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_002388</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3R1"/>
    <dbReference type="OrthoDB" id="432010at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF30">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="20"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8296986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="280" mass="31518" checksum="C1721FC2BF76B23C" modified="2020-04-22" version="1">MDDGNISLQILSHGPMNHASPELCQQINDELTAAISQNPSRLRGFATLPMGSPSAAAQELERCIKKLGFVGALIDNHLDGKFYDDEKFWDVFEKASALDVPIYIHPNFTSEKDMHKYKGNYSDDIAMGLANWGLGWHFDTGLHFLRLYSAGLFDRFPKLKIVLGHMGELLPFNLERIFKIARRWGRKRGLESVWEENLWVTTSGMFSLAPLACLVQTKGKDKILFSVDYPFSGNDTGREFVERVGESGIFGGLESREMRGFAYENAERLLKVKIVDGSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3R9</accession>
    <name>A0A5N6K3R9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the flavin-dependent halogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3R9"/>
    <dbReference type="OrthoDB" id="5278911at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050816">
        <property type="entry name" value="Flavin-dep_Halogenase_NPB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43747:SF5">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43747">
        <property type="entry name" value="FAD-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="370" mass="42409" checksum="DF129AC8049ACBAB" modified="2020-04-22" version="1">MEEFNTNAYWAYFECPGDEADFPLRHYESVNTNHICLPEGWAWVIRLPSWEGSSIPNLTAMINHLLDLNTAKIPADSYPSVRELVNRFQVKFRWVVSIGFALRSDVVYPENISSYGSNEAEQKFNWIISRYQKVSELMEKHKLIQDLYGPGTTWFVRKGLAFRTPRVTGRDWLAIGDATGFTNPLYSPGINANMSTSIYAAEMTKDYLSTKNTSSKKDLLQKYEQFCKDRILNLQRMNVLNYVCMRSPELGPLGPIWQYLCGTGNEKFQNAKNLNLQNVHELLTTWDWGSNQKEFIAFSKLAMQMLDGPPDAKLSPITIDAVKCLSADHLKLAMSSGKYTGRWAGLLRWKCVYCGWKHTIEESTKVLYQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3S8</accession>
    <name>A0A5N6K3S8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_002440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3S8"/>
    <dbReference type="OrthoDB" id="5325112at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF27">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8297042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="811" mass="91131" checksum="B7ED077240203ADE" modified="2020-04-22" version="1">MFVNLEGDVTRSTLDFAKYPEEIVVDGRGVDVDPVPSTMEEEEEGYVLASMAFEDGDVLRHGIEIQRWDLDPGEDAVQKFWLEAPLSSKASADEGESKIGLRTVIQPGDVYFDDVVDKLRLKRFQPCSLKSLNPSTLSMRSVESPTAMSLQRVSGERELFEESLSPGWETRRNDEEQQFAQRLGKSKSRVVTWSGNNVWWAVRNPLVVRLDAELGMDTGNEEVPSLDRKKAIELMNSLRGREAKTETEFVSLGYIRQKIGLLIFISLLTAPAGQATDTEYGAAEEALSEGSLDPRIILAIVPVLRNEIIEGKTGIWIHGGVKDAAENFMTMTSGIWDTQNPKTHGIMSEQVLRFLRRFLLSWRRRKGFGSISNETEVFKSVDAALLIVLLQLDTASPRGPARAKSIRAELNNLVDHGVDCFERAISLLQSYNRLYVLSRLYQSRKMTEEVLITWKRIIEGEEDEGGELLDGENEVRKYLINVRNPALVREYGVWLASRNPKLGVQVFADGQSRVKFEPIQALKILREGAPGAVKDFLEYLVFSKHHSEYINELIAYYLDIVTAKLEESPEARATLIQTYESYRALRPPKPTYRQFITENTLDEEWWHSRLRLLQLLGGSQGSASQYDVAAILARIAPYTQELVPEVIILDGRQSHHEEALRLLTHGLGDYDTAINYCLLGGSSIYHPISGTLSPATLPTRIEQAALFHSLLTEFLKIDDVSNRVEQTSSLLERFGGWFDVGDVLGMIPDTWSVELVSGFLVSALRRIVRERSETMVVKALSGADNLKASVAFVDRVRETGPKIEMEAEGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3T6</accession>
    <name>A0A5N6K3T6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">26S proteasome regulatory subunit 4 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_002409</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3T6"/>
    <dbReference type="OrthoDB" id="10255768at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000030">
        <property type="entry name" value="26S protease regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000007">
        <property type="entry name" value="26S proteasome regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000039">
        <property type="entry name" value="26S proteasome regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="244"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="114"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00068880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8297010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="502" mass="55548" checksum="41817C12415F3A4B" modified="2020-04-22" version="1">MGQQPSGLGGNPPGGDGKDDKSKKKDKPKYEPPPRPTTRIGRKKRKAAGPNASAKLPAVYPTSRCKLRYLRMQRIHDHLLLEEEYVENQERLRKAKAVKEGIVAPATAGGDADAADRNADERGRVDDMRGSPMGVGTLEEMIDDDHAIVSSTTGPEYYVSIMSFVDKDLLEPGASVLLHHKSVSIVGVLTDDTDPLVSVMKLDKAPTESYADIGGLESQIQEVRESVELPLLHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLVRQLFQVAAENAPSIVFIDEIDAIGTKRYESTSGGEREIQRTMLELLNQLDGFDDRGDVKVIMATNKIDTLDPALIRPGRIDRKILFENPDQHTKRKIFTLHTSKMSLNEDVDLEEFINQKDDLSGADIKAICSEAGLMALRERRMRVQMADFRAARERVLKTKSEGEPEGLYLAPASIRSSCILDIPWLMHLMVGRVFIPWFPSHLLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K440</accession>
    <name>A0A5N6K440_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUS-like FMN-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_002518</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K440"/>
    <dbReference type="OrthoDB" id="272303at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF5">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="4">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="233"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="314"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="314"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="356"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8297135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="378" mass="42130" checksum="6887277B9DCA3BA7" modified="2020-04-22" version="1">MVLSAGASILTVHGRTREMKGHKTGLADWGVLRFLRENLPKEVVLFANGNILAREDIDECLKATGADGIMSAEGNLYDPTIFSDAPAIGEEGREYWRSLDGTIGGWRMDAVFRRYMDIIYKHVLQRSPPERKPLFITSDPQEETKEEEEEEGPPKKKQKGEKKERTTSPSLVAMQPHCFKLLRPLVSNHHDIRDALAKCRAGDIQAFEHVLQMTEKVVKEGIMEYERTNGESYREEVERAEKEREEKMKGGGKGANGRGGADGDGEGKGGEELKFEESSLETVRRCKRPWWVVQPYVRPLPMEALAKGSITLSRKERGGKAKGEGEGEGDVEKDEGKLVNGVEPEEQGKVEVQVVGDKEVDNPEKETVEVPKDGLVCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K447</accession>
    <name>A0A5N6K447_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K447"/>
    <dbReference type="OrthoDB" id="428734at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000447">
        <property type="entry name" value="Glucose-repressible alcohol dehydrogenase transcriptional effector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF100">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="385"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8297097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="654" mass="73689" checksum="D3FC26B5E4B3C418" modified="2020-04-22" version="1">MADGYRFSQQSAGNYYYPQNTHHPRHLIRTGTPPNNVRSAFNTNTPSPTRTPDPQSPAHGLYSMFNHQQGQHGRVNGAGRGAMADHTRMIPYPHLMHQSQHTQHHANIQQDHNAHNSNGVGHHANFPSVGMQNSTSNFTPNLQNGHTTSTHGGQPPVINEHWQKQLELYQESKKAKLQGPHHFARSKSAQNTVDTKPVATTSNEEEPESATRNRPSNTDISIKRQDWHNMDMSGLGLRALSVEVFQYTFLRELYVAYNALTSLPSVIGQLRHLSHLDASGNALQTLPPELGMCVYLKNLLLFDNQLTSLPQSFGSLYQLEMLGIEGNKQMDPAIKSEIMEKGTKALIHTLKEEAPIPPPPAPREMIDLLNGTTVPPEVERFTVFSYNILCDNYVGPGQYGYVPSKALDWDHRRHEILREIEDRDADFVCLQEVDAENFREFFSVKLAYKDYKGVWWPKSRAKTMSESAAKAVDGCATFYKNNKYILLDKQLIDFANIAINRPDMKNQHDIFNRVMPRDHIAVLAFFENRLTGSRVIVANAHIFWDPAYADVKLIQIAILMESISKFADKYQRFPACKDKKAYTITDDSNPEAPVEVAPEPAPSMEYTNKTQIPLIVCGDLNSTADSSISETISMETSREMELSILSPFDPPTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5V0</accession>
    <name>A0A5N6K5V0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_001738</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5V0"/>
    <dbReference type="OrthoDB" id="5245063at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048379">
        <property type="entry name" value="Rad26-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022093">
        <property type="entry name" value="Rad26-like_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048380">
        <property type="entry name" value="Rad26-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21046">
        <property type="entry name" value="Rad26-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12331">
        <property type="entry name" value="Rad26-like_helical_rpts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21048">
        <property type="entry name" value="Rad26-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad26-like N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Rad26-like helical repeats" evidence="1">
        <location>
            <begin position="103"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Rad26-like C-terminal" evidence="2">
        <location>
            <begin position="310"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8297961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="380" mass="42781" checksum="85B7F2BF682ECF4A" modified="2020-04-22" version="1">MLDHRPNRDHLRTLEALGKHALPSSPNESFSSLILGEMPRIGAKKPISEVPSEFCLFLIHLWSKCMDERHYAPIYLFVDILKFALELKTLSIVPHIIDQLIPLVQKTADLVAIPRFKNELPDPYDKDINVSACLALTHLTALGCVPEQEHITRFWKLMRWDFVLLMLSQNQPVSDFEWMLRILSTGVLKGSFGSNPDDNPKFRASTNAGHIIERLTYPLFEVLPTSLGKVEADVVLKLRIQIILLMTGMTRSPYAGKALVSHPNAIGRVVSLISDELDNLYDHKAGHEDSARLISLATRLLFHLVTQYEFDMQKKLSVIRGGSQKYLLSLARLNFSEDDLVFESGIDPDIPGCALEMLEMVVTPEEGEAIQEALSFQIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5V4</accession>
    <name>A0A5N6K5V4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5V4"/>
    <dbReference type="OrthoDB" id="3825435at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="219" mass="24579" checksum="9CE73D83ECD55755" modified="2020-04-22" version="1">MDKQHAELVKSGMKDGDPVKAEAAAEKSIEEAAEEQSKIADQFAILAWAKLNGVTSEQIFDHMSESGKEFNSDDFSSLINKGARENRDHEKIESAKTAASTMGWSLTEWCQRLHGVNTPEEYLEKLGKIKEPEYMLTENAAQSKRLFREKLLCDAYGPGETSKGEFHSWDDVVLSMPFTEDWDALVGSGKNVEPTEYTLVPRMLQVNQFDGKELWVGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5V6</accession>
    <name>A0A5N6K5V6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_001751</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5V6"/>
    <dbReference type="OrthoDB" id="417037at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8297975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="419" mass="47447" checksum="1BC12371F48F71B6" modified="2020-04-22" version="1">MNGYSNGKGKEKDRYLPAKRRGGESGKWLDVVAFGAFSAASALILKYAISGQYWNLNFFLLALQSGCAITVIWLLKRGGYLREMAGLDLPKAKTWLPLSILLLVSNYISYKALQCLSLPTYILLSTTTIFTVPYVDSILFGTTIPPFAFRSYLLIFSGIIISVITENAHAEASYGDRRLEQTLEPQDPVMILFLGYVFMVVHLLLYSTYEAWKAKIVPNLKFGQWDIFLYNHALMFIITSILSFIIEDFSDENINDCFPSEVRQSTIIAIMYSCVGIFPILFFSTSIVRKSSHNVHSVVEASSKMVIALLGMYIYSHPINFFSVSAIIIGCFGGILGAWLQGKHQQDVKGKRVLPYNSTILHIAYKPHKNHWKRRILPSYLHNLRIGMRNDVDSTCLSKDRLKYSYPSKLSDTRDEITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K626</accession>
    <name>A0A5N6K626_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K626"/>
    <dbReference type="OrthoDB" id="125347at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="402" mass="43676" checksum="C2D6BA1EC1379CEE" modified="2020-04-22" version="1">MGILPKLMTITKETTPVEIRDCLMREFGAEVHLQQCRRAKTEILKKGGSGDEGSGGGGQGGGQGGGLGSDGPVPGNGSGNGSGNVNGGGSNNSSSKQQQHNNNNNNNNNNNNNNNNNSNNSNSGMPGTNLPPNQVLFPDMNAHTNRPPSTVNVPMNSAPPSQPPPRVEPPSTNRTGTSGSSPQFTLHAAQAIGNPAIPERTDATLMQANTMSGHGVVTEQPIRCPYCINQRWMRSIKDAVEHMNIHPHRAKVNKNLIITTCYSTTTTIIFSSFLSFSSPFPPLLAIFSSDQSVLKSHRKRKITSQMVTVRISTLHFQSQMKHPWYVLPAPLPSMNHPPNMQPNEQPKISGLPLSRKQKKKSITKGGIKNKKRHNKNAECLPIFSSFANRKFSQGKKRVWYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K661</accession>
    <name>A0A5N6K661_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K661"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF1">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05752)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="166" mass="18409" checksum="F3EC3181CE7E4B36" modified="2020-04-22" version="1">MKVLTILSSSKTTPKLFIDDVIQGKGKGLVAVLHGPPGTGKTLTAEGISELLKCPLYMVSAGELGTDPRTLEAELQKILDIAHAWGAVLLLDEADVFLEKRTIQDIHRNALVSIFLRLLEYFQGILFLTTNRVETFDDAFQSRIHIALRYGDLSTKAKKSVFKIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K662</accession>
    <name>A0A5N6K662_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_001832</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K662"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF9">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="569"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8298064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="653" mass="73832" checksum="99468F2E1ADFE5FB" modified="2020-04-22" version="1">MSERPAKRIRQACEPCRRKKTRCPGEKPICSHCSRLRQNCYYDDGSHNMAGRISIERTPMPTPSRAQETHSTSSSDGTLEDRLRSVEAQLAEVLANQVSMGTSASRQISDSPALSHLEQAMRTPNIPRLSSSCRHMKLSQVLQKHEGVLRDNKTELINGYSEAARSFISDRIFGGRVELSTLQSLCLLILVDFSNGNTRQASVCSSLAMSLAYNAGLTTESHAPSSDSICEERRRCFWSLFLLKKLHGAEFSVMDFTGEENFPWYPETTGKPLNPGHSTSGEIPDISSPEFAISNTQDKGVVAYAIQLSEVWFKITRYAKRRGSPSTLPPWSPQSDYALIMAQQMDFETRTSQIHRFKSAKFSQRSTEDLHANRDYWGPWLFIQFLYHTNLCLLNNPLLLSLRLKNIKSAIPEIFLQHISDLISSHASWVIRYIDMLEVRSFKVSDPFLAHCVAIIATIYLQEYFAEDPIVRQEKRDNFDKCLRFIRDFKEWPHVARMAEKLQRLRDTVSSTYKNPDAPPQTPNRSLLIDLGQFWEILEYSSSSEIPTSARRLFGPSLYSASIPTTHEISHASSLPEPTRVDRQDFEGSGPSSVKTSVVNMGEGGMTGQEQEAVHPPFHYSDDELAVLAESFFHQRGEGLGNLEDWWNAGNMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K663</accession>
    <name>A0A5N6K663_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001837</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K663"/>
    <dbReference type="OrthoDB" id="329272at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8298071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="88" mass="10176" checksum="D8B7A85DDFA6730F" modified="2020-04-22" version="1">MLREEEKKRVPEWRGLVCLHAREKAVETWGRNGFLVDEGMGTWWEYENTQTPIRCMALAHTINGIIQKTQLLPGSPSVNNIPPTIFRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K669</accession>
    <name>A0A5N6K669_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ZFAND1-like ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K669"/>
    <dbReference type="OrthoDB" id="431929at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057358">
        <property type="entry name" value="UBL_ZFAND1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25327">
        <property type="entry name" value="UBL_ZFAND1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZFAND1-like ubiquitin-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="71" mass="7679" checksum="4001CF47F56F2798" modified="2020-04-22" version="1">MGRVLDAAAKGLQVENVNNQGTDEKEKLRIFHVEAGRLLEFNEKVGDALVNGNRIVLLRGVGPAVPDLIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K673</accession>
    <name>A0A5N6K673_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K673"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="123" mass="14221" checksum="97174D22A68A645D" modified="2020-04-22" version="1">MGFWRDMAGSFFFSKHLIGVSDSNSLGKWKGRLRIQGGGIDNHWYWQCLILYSFIIFLWRIRWVVFGGMACAEYKVGWMDEQMIHMGSEAGIYGTLTASEILCATLFIYLPNPLLYSLVLNEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7V5</accession>
    <name>A0A5N6K7V5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Galactose oxidase-like Early set domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_000974</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7V5"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF21">
        <property type="entry name" value="LOW QUALITY PROTEIN: ALDEHYDE OXIDASE GLOX-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glyoxal oxidase N-terminal" evidence="2">
        <location>
            <begin position="29"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose oxidase-like Early set" evidence="3">
        <location>
            <begin position="400"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8298803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="57306" checksum="AE105451682C1913" modified="2020-04-22" version="1">MHAALMPNGRVMFLDKLENYTQLRLPNGNYAMSSEYDPVSNGVSVPLAYKTNAFCSGGTFLADGRVVSLGGNAPLEWLDPTIGDGFDAIRYLERSSTDASLTGKDWSEPGNKLASARWYATAQTMPDGTIFVASGSLNGLDPTVKANNNPTYEILSATAVSQGKNIDLEILEKNQPYYMYPFVHLLNDGNLFIFASKSSQVFNVGTNTVVKELPELAGDYRTYPNTGGSVLLPLSSANKWNPDIVICGGGAYQDITSPTDPSCGRIQPLSANPQWELDSMPEGRGMVEGTLLPDGTVIWLNGGNLGAQGFGLAKNPTLEALLYNPTKAKGQRFTTLAASTIPRLYHSVSLLLLDGTLMVTGSNPVEMPKLQPDAADPYVTEFRVENYVPPYLRGDNANKRPTNVKLSSGSFKADGSTLTVTFNCPAGAKAVTVTLYHGGFVTHSVHMGHRMLYLDSTGFVAGATQQKLTVTRPPNSNVAPPGPYVVYILVDGIPAMGHFCCIAWFGKGIIRRGADIQNCTQGQVRPGLKIKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7Z3</accession>
    <name>A0A5N6K7Z3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7Z3"/>
    <dbReference type="OrthoDB" id="196717at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="102" mass="11218" checksum="F96D99CAB7FDE99C" modified="2020-04-22" version="1">MITAHLVKLPFPYTNVLNLPLAYGVFDSAGPFLKETFGLGWPSALGGGVYQVAYLFCMLGVAVGVYGSFVVDVIVTICDYLDIWCLTIKHPWNEEEEAKKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7Z9</accession>
    <name>A0A5N6K7Z9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">EYC80_001030</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7Z9"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000702">
        <property type="entry name" value="ABC transporter (Adp1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="679"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="714"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="756"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="792"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="822"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="908"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="216"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="513"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="534"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAB8298870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="934" mass="103294" checksum="1EFE2A0C855E4A9A" modified="2020-04-22" version="1">MCDVTNRKIVDILDGKKPQVTFTCNAEVETCDFQFWVDEKESFYCSLDTCTSGAENDYDRNSTSAKCENIACKCVPDRMLCGENGSVDISDFLDQEIRGPATFNCEQKSGSNECTFKEPQMDLLIQQMFGDSSIFINCQAGECLYETEIPGYERPIKKINTPLIAGVIAAASLFVVGVILLVWYLSRRQFKYGPIHLDDSDDESIKLMTDHKPASLYFENVSYNLNGKQILTGIQGVAHPGEIMAIMGASGAGKTTFLDILARKNKRGVVQGNYYVNGEKVTDNEYRSVIGFVDQEDAMLPTLTVHETIMTSALLRLPRDMGRSAKEQRVFEVERQLGISHIKDSLIGSEDGKGRGISGGEKRRVGIACELVTSPSILFLDEPTSGLDAYNAFNVIECLVNLAKTYKRTVIFTIHQPRSNIVALFDRLLLLAKGRTVYSGEFSLCQEYFDHIGYSCPPGFNIADYLVDLTMHVGTPRTPIDDASSEFRHGIAPSVGASSTRAVKSIASISGGSIEEPVVGSPSESLLRPKGKRRDSVKARQERELFTRKKSGIDTPTSQPDEAPVDPDANQHWLRMSRQHSSIAEDPDNLPPDAPGSGTDLDVLVSAYAHSPISRDFQDDLKNAVSAAQSANGSINGHVQENNATSTNTMGRGYARVGYLRQFVILSQRTWRNLYRNPMLMLTHYAIAILLAVLSGFLFYGLTDDIPGFQNRLGLFFFILALFGFSTLSSLNVFATERMVFVRERANGYYSPITYFLAKVVFDIVPLRIIPPLIMGSILYPMTGLVAEAPNFFKFLLILVLFNLAAAAICLFLGIVFKDNGVASLIGSLVMLFSLLFAGLLLNHDAIPKSALWLQSLSIFHYGFESLIVNEVTYLTLVDQKYKLDITVPGAVILSSFGFDTQAFWPDAINLAIFAGAFIFLAYVAMHFLLVERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K865</accession>
    <name>A0A5N6K865_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K865"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="95" mass="11567" checksum="215F86D51FF50BEC" modified="2020-04-22" version="1">MNEQQEEYPRGGRGRGRVEEEEEEEEEEEEEEEEEEEEEEEEEEEKRKRKRKGMTKLKNTKNTIDEREGLRRKRRASQERINEQSAINNQQAASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K874</accession>
    <name>A0A5N6K874_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K874"/>
    <dbReference type="OrthoDB" id="27298at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8298988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="143" mass="15651" checksum="14BD0A3CE877FF5C" modified="2020-04-22" version="1">MITQNLPLLPALLQTSVLALLSASIPLSMAMTSVLLALRNTETGTVITENPTPFECQDAASVHVLAFTSHGELLVSESEGSFDMDEWDEIYEHAKGLCCKGHGSIEDDIMHEDGLENETNSSLMMFVKSTVQEKVNTDLHWKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K875</accession>
    <name>A0A5N6K875_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K875"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="49116" checksum="4A94F74339A6DE87" modified="2020-04-22" version="1">MLIIEQIAHGNSSTTLSDNMVFGERYGSLTVSSQTSWEESPPEQGEGGSIFQNHENLTEPASKVMQKFGLTWENDVEDILTIKDTFQEFAKGQRPQSYRHRVAFKVKGYNPGQVRAAVERSLLKRPILRTILVGDPGATAVHAVLRPSHVVYDILIKQESFSHESEVQETLVDDFGERFEARMFKAIVADIGGKDTALIITLNHSVFDALFAYSWYSDLDMFIQKPDFVPAPTMPFKLFADIHQQYKNSSLALSDINFHIRRLRGISRFTEALWPLKRAPGWMIGNDEGSKDFIVRRKWPFLPGWIADRLPSAMSINGPTLTWTMNMIQIKPAETCGELLTRMGRDQEELSSRAHAPWYQVLNGLGDDEGPIAKEASMRQVFNWDVSLKHLDSSVNDYKTLSPMGRMDWPDCGFFWNCGYVEHGTLLLCRVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K876</accession>
    <name>A0A5N6K876_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_001137</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K876"/>
    <dbReference type="OrthoDB" id="5348404at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005178">
        <property type="entry name" value="Ostalpha/TMEM184C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23423">
        <property type="entry name" value="ORGANIC SOLUTE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03619">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01417">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="426"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="522"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="437"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="522"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8299002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="580" mass="65442" checksum="6671761D713C0561" modified="2020-04-22" version="1">MFINTTCNATLDDMRIGRSEAILVADLTFHQLGIVLSAATALIAILLSLYLMWMHALHYTKPYEQRHIIRILFMVPIYSVASFLSFWQYWHEIYYSVISECYEAFAIASFFALLCHYIAPDLHSQKVYFRTAIPTPWVWPVTWMRKCCGGDKGPWRTPRSGLTWFNIVWAGVYQYCFIRVTMTVLAVVTQYFGKYCDSSDSPVFAHIWILVIEGAAVTVAMFCLIQFYVQLRTDLAPHKPFLKVVAIKAVIFLSFWQSFAISILMSSTIGMVKPTKYLAYPDLKIGIPNLLLCIEMAIFSVLHLFAFPWRPYASNATPVKYPSSPDGGLQPIGPKQGGPLGLMAFADAMNPWDLVKAFARSMRWLHRTTLTMTCRSNLQTRKGKHLSKHGDDGLPIANAYRSNTFGSNKGAMEGYTSAAQRYTPEGRDITTNGMQHNNNNNNNNNNNSNNSNNNNNNNNNNNNNPDRLVAHNPTPGSMRRQEKPIGVAVSGGPESYLSQVARPISPYGVRQLSEPELFLEQKRAKRAAEKAARDRADQEERERSARPSEQWANSRVPVQPHEPPSHVHNALWGSQAQPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBN0</accession>
    <name>A0A5N6KBN0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_000713</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBN0"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF92">
        <property type="entry name" value="AGL026WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="63"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8300554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="418" mass="45802" checksum="1A02EAB07E3561A0" modified="2020-04-22" version="1">MATAGIPTTDIDTKIQSNDVELLEDALSTPDKSSRIPEYVRNLTPEDRKRTESSLKRKVDTRLLPMVVLIYIMNYLDRNNIAAAKLAGLERDLKMTGEQFQTSVSILFVGYLLMQVPSNLLLNKLGKPSLYLPGCMVVWGIVSGATAACQTYGGLLACRFILGFVEAAYFPGCLYYLSAWYTRKELVKRTAILYSGSLLSGAFSGLISAGITNGLDGAKGLSAWRWLFIVEGAITVLIAFLAFFILPDLPRTTNWLSKDEKELAAWRLEEDIGQDDWVDSKQQTFFYGAKLALKDPKAWLLLATIYGFTSAGTVTTLFPSVVKGLGKNNITTLLLTTPPYLIAVIAILCNAWHADATGERFLHIALPPVLAFISFAIAAGTTKFAPRYLAMCLMVGANYSGYVVALSWISNGALSQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBN4</accession>
    <name>A0A5N6KBN4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mannosyltransferase</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_000415</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 22 family. PIGZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBN4"/>
    <dbReference type="OrthoDB" id="10066429at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF3">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024806845" description="Mannosyltransferase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8300189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="497" mass="56584" checksum="5E6F196E8529B70D" modified="2020-04-22" version="1">MPFFRRAYLLVLLLRLWFAISPSYLHPDENFQGPEVIAGQIFSYPVKLTWEFTSDNPIRSFFFALRLLMLTLSFVLEDWAIYELVESPKHRKVAVMLVASSYVTWTYQTHTFSNSIETLAVAWSLVLIQRIVAAKKHSSVLPCGILAFVVVFGIFNRITFPAFLFIPGLRLLPHFKRKPLSLISMILFGGLATFIAICLDTNFYANGPVTWSHLFTHPTITPFNNLNYNLATENLALHGLHPWYQHSLINLPQLLGPATLLLFLQPLASLRLYSAISGIVVLSFFKHQEARFLLPTIPLILSSVKLPKNRIALRIWGALWIVFNLLLGLLMGVYHQGGVVPTQVFLSKQLDATHAIWWKTYSPPIWLLNGKNEVLATHDLMGMQAERMLEEVIKMATCLPKSGEEFTEATYLIAPTSATFLDKYTANQTNLYFEEMWRYRNHFNLDDMDFGDDGFWNTITRIIGRRGIAAWRVTVDCPGGEKDMDKLGGISENETSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDN0</accession>
    <name>A0A5N6KDN0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thiamine thiazole synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Thiazole biosynthetic enzyme</fullName>
            <ecNumber evidence="6">2.4.2.60</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_003334</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[ADP-thiazole synthase]-L-cysteine + glycine + NAD(+) = [ADP-thiazole synthase]-dehydroalanine + ADP-5-ethyl-4-methylthiazole-2-carboxylate + nicotinamide + 3 H2O + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:55708"/>
            <dbReference type="Rhea" id="RHEA-COMP:14264"/>
            <dbReference type="Rhea" id="RHEA-COMP:14265"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:90873"/>
            <dbReference type="ChEBI" id="CHEBI:139151"/>
            <dbReference type="EC" id="2.4.2.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homooctamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">During the catalytic reaction, a sulfide is transferred from Cys-217 to a reaction intermediate, generating a dehydroalanine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the THI4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.60" evidence="6"/>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDN0"/>
    <dbReference type="OrthoDB" id="410463at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160205">
        <property type="term" value="F:cysteine-dependent adenosine diphosphate thiazole synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052837">
        <property type="term" value="P:thiazole biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03158">
        <property type="entry name" value="THI4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027495">
        <property type="entry name" value="Sti35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002922">
        <property type="entry name" value="Thi4_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00292">
        <property type="entry name" value="sulfide-dependent adenosine diphosphate thiazole synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43422">
        <property type="entry name" value="THIAMINE THIAZOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43422:SF3">
        <property type="entry name" value="THIAMINE THIAZOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01946">
        <property type="entry name" value="Thi4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="110"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="296"/>
            <end position="298"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="2,3-didehydroalanine (Cys)" evidence="6">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8301475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="328" mass="35111" checksum="D42AD5A714111840" modified="2020-04-22" version="1">MAPPSAMFPEATSPIDGVQLKTGFDVKVAPAQAATQGKTLADLAEKWDQGFTFAPIRESQVSRAMTRRYFNDLDTYAESDIVIVGAGSCGLSTAYMLGKARPDLKIAVIEASVSPGGGAWLGGQLFSAMVMRKPADAFLTDLGVPFEDEGDFVVVKHAALFTSTLLSKVLTFPNIKLFNATSVEDLITRQDDDGNIRIAGVVTNWTLVTMHHDDQSCMDPNTINAPIVISTTGHDGPFGAFCVKRLVSMNQIKELGGMRGLDMNVAEDAIVKRTREIVPGLIVGGMELSEVDGANRMGPTFGAMALSGVKAAEEALKIFDERKAENAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDN2</accession>
    <name>A0A5N6KDN2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyruvate dehydrogenase E1 component subunit alpha</fullName>
            <ecNumber evidence="5">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_003423</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="5"/>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDN2"/>
    <dbReference type="OrthoDB" id="10256198at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02000">
        <property type="entry name" value="TPP_E1_PDC_ADC_BCADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000013">
        <property type="entry name" value="Pyruvate dehydrogenase E1 component subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050642">
        <property type="entry name" value="PDH_E1_Alpha_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017597">
        <property type="entry name" value="Pyrv_DH_E1_asu_subgrp-y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03182">
        <property type="entry name" value="PDH_E1_alph_y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF60">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Dehydrogenase E1 component" evidence="6">
        <location>
            <begin position="85"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8301579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="409" mass="45370" checksum="C8195A6FC6D58152" modified="2020-04-22" version="1">MFSRALKARSAAPLRSNAISRVALAKRTVTTDAASAHADKDAVPQEDDKTFTIQLSDESFETYELDPPSYTLDTTKKELKQMYIDMVSMRRMEMAADRLYKEKKIRGFCHLSTGQEAVAVGIEHSLTKEDDIITAYRCHGFALMRGASVKSIIGELLGRREGIAYGKGGSMHMFTKGFYGGNGIVGAQVPVGAGLAFAHKYNGNKNVSVSLYGDGASNQGQVFEAFNMAKLWDLPVLFGCENNKYGMGTAANRSSALTDYYKRGQYIPGLKVNGMDALAVKAAVKHAKDYANAGNGPLVLEYVTYRYGGHSMSDPGTTYRTREEIQRMRSTQDPIAGLKQKLIEWNVTTEDELKAIDKEARAKVDAEVKEAEEMPFPDATPQILYEDIYVRGSEPQYMRGRTNDENYYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDN5</accession>
    <name>A0A5N6KDN5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_003313</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDN5"/>
    <dbReference type="OrthoDB" id="5329176at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="328"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8301448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="433" mass="49047" checksum="50F960F6C859B17F" modified="2020-04-22" version="1">MILLAMVPTTAFFVLSLLADLKFMWTRHQYDIPLSHVEFGLKMVLIIEVMFAAACTFTKLSMLMLVRRMLTSASMFWRRVTLAAICIVGLQGGLFCIVLVFQCRPPQDYWRLTLDPQPNCIDQSSTLLLAGVVNTLTDFLVVILPIRTVYSTNLPRRQQFLVSLLFILGLLSCFAGIVRTYYMYVVTQVWDQVWASYPVWISAAVELYIGIICTSIPATKAFFVTYIPKLFSSHTSRTTRTDTDHHPNYNPYFNSKGDPIPYPGFGITSTSKSHPRTLTRESSMTPLNAENSLHDNTVGTSILELASITNTIRGNSNEKHDEEMEIGMVVGTPPSPSFDGRINSHDNSSKPRNSSIPRRIIGSVRRDRGRTRDRDGYGETTASEESSGHTRSMEKEREREKEGGWDIHIGVVKTIEVEEEHIEEEIRDYDTHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDN9</accession>
    <name>A0A5N6KDN9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_003341</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDN9"/>
    <dbReference type="OrthoDB" id="7457040at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042171">
        <property type="term" value="F:lysophosphatidic acid acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035965">
        <property type="term" value="P:cardiolipin acyl-chain remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886:SF29">
        <property type="entry name" value="PUMMELIG, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886">
        <property type="entry name" value="RE40534P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="84"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="202"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="215"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8301485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="477" mass="53074" checksum="FC7ACCBAB6A893A8" modified="2020-04-22" version="1">MSFVPYLQKPPTHTQTGSAPVSAGTSTLSVNDGPNALSIPVRTNSINDPHGPRQWHSNLVKLSGKNRALNEFSVERTGEKVEDTLVMLHGYGAGLGFFYKNFEGLSRVPGWKIYALDMLGMGRSTRPSFKISAKDQAGKIAETEGWFIDALEEWRVLKKIDKFTLLGHSMGGYMAVAYALKYPGHLNKLILASPVGIPEDPYATSAAMPEPDESTLASEFTQDQEADIVSTSGSRTNEGDNNNFGNMRNKRENNKSKQETAKRPLPFWLTYLWDANVSPFSLVRWAGPLGPRLVSGWTSRRFSHLPSNENDALHMYAYSLFRQRGSGEYALPYILAPGAFARSPLIRRIHGVGRQPIPPSPQSPPNFGQKEHGYPILLMYGENDWMDIAGGYAAEQACKEEREMVLAKASKEEKELENGSAKVVIIQKAGHHLYLDGWEEFNEFMRGEMKQTTIDGQKMKKTLEKLGVEVEDRSQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDS0</accession>
    <name>A0A5N6KDS0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDS0"/>
    <dbReference type="OrthoDB" id="2958217at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="24797" checksum="36AB9849FDDC5DFE" modified="2020-04-22" version="1">MVYIVIGTKYLAGFVKTDPWASLLWCRDESQIKQRAGLRYKEYVAPTWSWASIDAPVLFYEAKSRHWRKPQLGPSPMDPKLNRAEVQPVSSFDTGEVKSGIVEILTYAVVVLTASVEPFLFNTRQGAHTYGRRNCVDPLTGKALGLIVFDVALEAEDDLLLCCVLLQTTDMSLWEKNGTAGLGLALRVEEATSKHLKCTRVGYVQFTSEFAALSEKRCIELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDU2</accession>
    <name>A0A5N6KDU2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDU2"/>
    <dbReference type="OrthoDB" id="3553547at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="564"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="395"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="479"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="564"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8301555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="589" mass="67977" checksum="0BBB4402F8CB9EE9" modified="2020-04-22" version="1">MRAEVEDSSRVFLQPYGIRQEEKSTQNKVEVKEIKQKNRRSEDLDSMVPVAPDFERTGQDARKPSKPKPRRKKKKNNNNLYITTKPEIQKHSCSDSEQDKNSMVFHEVEPRLAMEQEYHRGSIFHSSLIPCVLNSTAPRKLHHLDPLEEVAPTSQSSKGINSAYTPSHGISESKLKDLSLPHIIHNVKSTEESQPIRHIREKVPHQSPDVDINIYTRSQSDPTIPSSRSQVYFNENGRRHSEPNHVYWKAPSFASNLPTVSEQIIQKSTWGHSINLCESIKTLNRGVFMEDFSTADSPNMQGHFESSDRHVEDASSKFEPSMLCDRWQGISQTRSHISALRETLRVMRFRLRSLRDDKSLADDAYFKEVKMRELNMAFPRSWWPSKTLEELVCDSQKARDEYGPLEDEYNNLENNLSSQEYQLSQQEEHFYSELRDPSRFISAPIDSGKVRCLSEEPEHLKPHESHPLVEAYMYKLGDLDILRERYDDILDEKLNLEEQLALRKPFGMILMPENQQWLDSSQAQLDNLASKIQVTEIEENKLRQQCFSMGLVDENGEPIETLRLNQPGSTSSTCLDRFDSPPGGPRDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDV1</accession>
    <name>A0A5N6KDV1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_003384</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDV1"/>
    <dbReference type="OrthoDB" id="21018at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072354">
        <property type="term" value="F:histone H3T3 kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024604">
        <property type="entry name" value="GSG2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419">
        <property type="entry name" value="INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419:SF18">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HASPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12330">
        <property type="entry name" value="Haspin_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01331">
        <property type="entry name" value="DUF3635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine/threonine-protein kinase haspin C-terminal" evidence="10">
        <location>
            <begin position="184"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="115"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8301538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="353" mass="39587" checksum="AAFAB94BD45CD1B6" modified="2020-04-22" version="1">MRLMNALTEIPGFVKFKDAHIVEGKPPAAFVEAYEGHLNAGGESYFPHPNKISKHAVFLAIELGDAGHVLEKYPIQNIDQLWDIFLGVVFALARAEIEYEFEHRDLHENNICILEHSPPSTQKSKSNPKARDHSPHSPHKFGNSGLEITILDYGLSRATIYPTPTPSNPSPAPETVSYNLESDPAVFSSFEPGTIAGIQFDTYRRMRAYLFSSGTSNTNANTPSKPIREAIKNKSHSWAEYMPYTNVLWLYFLIEYLTEVAPKGGRGRGKQGKQTWVKETAELRWLLHPDWVPGDAENNQRNQDPDNQPTQEDEELGLGCAGDVLQYAFDMGWIREGDLDAVDSSRLSLRDCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KE34</accession>
    <name>A0A5N6KE34_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SMC hinge domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_003445</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMC family. SMC3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KE34"/>
    <dbReference type="OrthoDB" id="431497at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03272">
        <property type="entry name" value="ABC_SMC3_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000424">
        <property type="entry name" value="Structural maintenance of chromosomes 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041741">
        <property type="entry name" value="SMC3_ABC_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43977">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="8">
        <location>
            <begin position="522"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="187"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="267"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="413"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8301604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="693" mass="78723" checksum="9A54B725EC0361FB" modified="2020-04-22" version="1">MVYIKQINIQGFKSYKDQTLIDEFSPATNVIVGRNGSGKSNFFAAIRFVLSDAYTQMGREERQALLHEGSGSAVMSAYVEIIFDNSDGRFPTGKNELYLRRTIGLKKDEYSLDKKTATKTDVLNLLETAGFSRSNPYYIVPQGRVTALTNMKDGERLNLLKEVAGTQVYEQRRTESLKIMTDTNNKRAKIDELLDYIKERLAELEEEKEELRGYQEKDKDRRCLQYAFFHQEQEAIAEKLEEIDEFRQGGGDGDENRDAFLDGEKAIAQLDSQIKQLTRQMELLRVDRRQLEEDRRDTAKARAKIELDVKTLTANQSSTEQARVRHQQELSSVKKEIALKEAELAQLLPDFTSKKANEAEVKRNLDEAEAGRNRLYAKQARSNQYKTKAERDRFLKKEIEELNSTIGSQKANRIDGDEEVKNVQSEIRNLETEISGLQERLNGWSGNRIALAEEVSTAKDALEKLQDERKLLRREDEKLHSVIEDARKEVSMAESELSRTMDSATSRGLATVRRLKQQHNIQGAYGTLAELLEVEELYRVAVEQTAGSSLFNYVVDNEETATQLINALNADKGGRITFVPLSQLRSKPANLPNASDAIPMLSKIRYDKKYQPAFEQVFGKTIVCPNLTIAAQYARSHGCNAITPDGDTTNRKGALTGGYLNPKESRIQAVRALNKWRDDNKRLIKRCANSMMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KE59</accession>
    <name>A0A5N6KE59_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_003489</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KE59"/>
    <dbReference type="OrthoDB" id="5424793at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09083">
        <property type="entry name" value="EEP-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000101">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="7">
        <location>
            <begin position="72"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="406"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="408"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="420"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8301651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="969" mass="108906" checksum="5E01C158F840D422" modified="2020-04-22" version="1">MTREKTLSNFEDERIFISTSSKNNNSTSIPVRVITHNIRYATESPFKGEELWSIRCPRLCSELVFNSTKPETFICLQEVLHSQLIDIHNALNQGPGSEWSHLGVGRDDGKESGEYSPIFYRPAVWDLVLYRTFWLSETPDKPSFGWDAGCIRLVTLGIFRHWSTNEVVVIMSTHLDNAGPISRQKSAELILEKVGHYKSIYAPAALLLAGDFNSPPDDEAYKTMTSPISSMTDVRDLIPEKNRYGNELTFTSFGYVDNTPTRIDFIFSAKATSVRYGTYAVLSNRYDDGVYLSDHRAVVADIEFERLAMSARLVIYSSHVLGLHVLRLLPIKLFSIPLTILELFHTAQSFFFFLIFMKVKHKTIVEIRLHPRFSMLHRFGSVYPRPDDNAICQRCHQTKGQCIVREKARPRRSRGARRAGRLEPPKVEDSPLSSNTSISTENPLKDGEFSLDLPTAVYHDPKKDAEFLQDHHKRIFKDDNSRSPTPSKEILHLPPKYISSRKLTLSQATHLLNSYIPKLPFFPFVTLPGSPTIPTLSQQSPFLLLAILTVAAIPHPYLHHQLDQEFRRVLSLKLIVESQKSLDYLLGLLVYIAWYPVHTKPKLNPCSTYMNLANSLALDLGLDQERPQIGPFREFDLKGLVDSNGNWTVEAKRAYMGCYVLGSQSFNKPQIVSYDNLLPSNGDSFIPSIRNTPATAIVILERISDRINDTWTAKTYPQMDTLSTELYIQVFAAELETWKRNVPESITTSPLLALYHKFTHLSLYSHSLRLLRRPAAIESSASEKFDTSSNKGRRKQLDKYFIMHGMLSTVKKTWEKRVEAIAPKASTISRGKCPVFDPGMASLLESASLDFDFGDMEAWDDNLDEAMMEWNNNIEEVGTSSTFSASNSKTPGDGEVGLQVVSGENVTIGGGEVSGVSQHGSGGTIYNDLWATMTCSWAEQPPAWSILDLEGVNIGGNGGGVFGYQVNEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KE62</accession>
    <name>A0A5N6KE62_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KE62"/>
    <dbReference type="OrthoDB" id="5580488at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="168" mass="19149" checksum="888410B50EC62AFA" modified="2020-04-22" version="1">MVGMASHQDESFVLRHNVEMDLERSRKKNTDISNENNNPNLCLSTKQQLTHESLENLQNLDPIIVESREPLSMEDHCRADHDHSDPTITISSTSKLAGQTVAPFLAKHIPEQYAPLGPPQSISTSRKDPNTKYCYRHRPDSKCRRTADEPTMENLQRVRRTISPSYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KE63</accession>
    <name>A0A5N6KE63_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycoside hydrolase family 3 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_005441</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8301987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KE63"/>
    <dbReference type="OrthoDB" id="4215304at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000008">
        <property type="entry name" value="Beta-N-acetylglucosaminidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000013">
        <property type="entry name" value="Glycoside hydrolase family 3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050226">
        <property type="entry name" value="NagZ_Beta-hexosaminidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30480">
        <property type="entry name" value="BETA-HEXOSAMINIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30480:SF8">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 3 N-terminal" evidence="6">
        <location>
            <begin position="19"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="815"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8301987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="923" mass="100125" checksum="8D6FE8D2F61C8CD4" modified="2020-04-22" version="1">MDVTEEELDPVWKDLDWAMGQCFMVGFEGTEVTPQIRTLIEDHHLGAILLSTKNLKTARQTANLVQELQTIAHEAGHPVPLIIALDQENGGVNSLFDEDYICQFPSAMGVAATGSLELAYEVANATAKELSAVGVNMIMGPCLDVLTNARYQPLGVRATGDDPQEVSQYGIAAMNGYKDAGIATCGKHFPSYGNLDFLGSSLDMPIITETLEQLSLGALVPFRNAIREGMDSIMVGGCAIANAGMNVMHACLSDQVVDDLLRNDLGFNGVVVSECLEMEALSHDIGVRGGTVMAVEAGCDLVLLCRSYAVQREAIAGLKLGLENDMISRDRINLSLKRALKVKSQCTSWAKALNPLGINHLASLHPSHLALSTKAYDHSITVMRDKGHLLPLSNSYSEDDDDLLLLTPLVKPLPASAATASLNSENTKFINTEAEKSHKSSIMSGEGVFRELGRALARQRHGRLLHTSYTANGVRPVHENLINRAGTIIIITADATRNLYQNGFTKHVAMMCSILSSAGKKKSLIVVSVSSPYDFAMDKSIGTYVCTFDFTETAMKALVRALFGDFVPQGTLPGTLRKSRKVQKPRQHWLVESYNKDRDTRGLQELIKSIEKTTPPNQQPALGGAIADSFELPPPVNYTPLEESHYVVLNSSTQALFGFCSTTYSPNTHTGTISSTLPAIYLGIPMSDLTEGARLKRWFATNGWDVVSPRLLYTLIIRNVAFWTPPEGLFATIQRVSLQFDLIHGPSYSATQVLDFVQTHSSSAEILSIYNLAIADPKSCGIVRAKSPIDGSLVGTVIISRSDTLLSRWMPVLSSSSSSYSHSQNTNASNSKGKEKEDGNRNGLGGIIAPVIPANNAQRETILQGLVMLSIRQNKNKGDGKGVVLNWVVGGDRDVLLGMGFDVLEAWEEVVCGVERWSKMNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KE69</accession>
    <name>A0A5N6KE69_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KE69"/>
    <dbReference type="OrthoDB" id="3473155at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="227" mass="27061" checksum="FAAF8EE02078F249" modified="2020-04-22" version="1">MPDHRLEEEGKFHTEMYVGVKAYDVEGGQEKEKALARRYSEFKINRFSSFHAVYQNFNGLRINGEVDLKWFVPMPCYMGEDWYAITTFILKHTILNWPPFDCTENKVEDWLNQPEYTFYYGIWQTYRKWMLRDWVEKQPEAIEYKKLHGLGEGNEKTKSLRHGLQMLRLVNVRTEKQKLMINEVVEAMMKNFRGRVDEIEALQDVMDINARMQVLEIDDEGLDGRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFR1</accession>
    <name>A0A5N6KFR1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFR1"/>
    <dbReference type="OrthoDB" id="1732691at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="68" mass="8000" checksum="E800D88E8BA921E4" modified="2020-04-22" version="1">MKVRQSYIINGIHLKSLVRLKYKVSPPDLHFTPLSMIRPQSTINQGYWWSVLKKDCKIYANVKLSIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFR7</accession>
    <name>A0A5N6KFR7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_005977</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NFYB/HAP3 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFR7"/>
    <dbReference type="OrthoDB" id="386949at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22907">
        <property type="entry name" value="HFD_NFYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000039">
        <property type="entry name" value="Nuclear transcription Y subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027113">
        <property type="entry name" value="Transc_fact_NFYB/HAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003956">
        <property type="entry name" value="Transcrpt_fac_NFYB/HAP3_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064">
        <property type="entry name" value="CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064:SF9">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00615">
        <property type="entry name" value="CCAATSUBUNTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00685">
        <property type="entry name" value="NFYB_HAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="6">
        <location>
            <begin position="45"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="133"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8302604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="270" mass="29426" checksum="58677671ACAC6A01" modified="2020-04-22" version="1">MSNSPPKETDVEQGVSPDDTDAQMNEHTDPHAPGGYEFEVKEQDRWLPIANVARIMKTALPENAKIAKEAKECMQECVSEFISFITSEASEKCHQEKRKTVNGEDILFAMTSLGFENYAEALKIYLSKYREQQSTRGDNQNRPGSSGFGPTPGATSANATSATFSGGAEGANNVLTGQQVEAEHDSGAYVYGAAHNGASGGEGPSRDELNSLEIIFREGIKYRQRCWEGGLRQVLNGPLLRYPDRIPYFLALESERPITSAGIGLGTAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFS0</accession>
    <name>A0A5N6KFS0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane protein 14C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_005982</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFS0"/>
    <dbReference type="OrthoDB" id="5620at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="entry name" value="Transmembrane protein 14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 14, 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668:SF15">
        <property type="entry name" value="UPF0136 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03720)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8302610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="18435" checksum="3CCA2066B272489A" modified="2020-04-22" version="1">MGIELPAYILGALTAGGGTMGYVRTGSIPSVAAGLTVGSLYLLGGYRIQNRQSYGVEFALLASIVLAGSSIPRAIRSQKPLPAGLSLLALYGLFTFGNAFRAQNLRNVLHVKMKKFPSFHCKFIIMAELSCCVNAIQSIFNDIQTPRPRILTPLLDKPIRPSPGGVFVNPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFS2</accession>
    <name>A0A5N6KFS2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trimethylguanosine synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cap-specific guanine-N(2) methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_005985</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78479"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="Rhea" id="RHEA-COMP:19089"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:78480"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="Rhea" id="RHEA-COMP:19090"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:78508"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78471"/>
            <dbReference type="Rhea" id="RHEA-COMP:19085"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:78472"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78475"/>
            <dbReference type="Rhea" id="RHEA-COMP:19086"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78476"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFS2"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071164">
        <property type="term" value="F:RNA cap trimethylguanosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000270">
        <property type="entry name" value="RNA methylase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019012">
        <property type="entry name" value="RNA_cap_Gua-N2-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741:SF32">
        <property type="entry name" value="TRIMETHYLGUANOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09445">
        <property type="entry name" value="Methyltransf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00018517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8302614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="300" mass="34237" checksum="56948AC3E716169A" modified="2020-04-22" version="1">MVVNGSNSHGHVPAVEYEEYQDNGDPAQFKLDDKCTHYTSLKEVPWDLHKYWQQRYSMFSLYDYGIYMTDDAWFGVTPEPVANKIAEDYASSMSPKKTTIIDLFAGAGGNSIAFALSNRWNHVIAIEKDPSVIACAENNAYIYGITNITWVNGDCFEYLKTHASSIDPSETVVFASPPWGGPGYTTENIFDLSTMQPYSVQYIHEACKTMDTALYLPRTSDLRQITKLLPEGKKVELVQYCMEGAKMLFGSFVADQHRLLGLFMREKNLLHELKNLHREMRYYGESMLEQCKIYIMLNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFS4</accession>
    <name>A0A5N6KFS4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptide hydrolase</fullName>
            <ecNumber evidence="3">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_005606</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="3"/>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFS4"/>
    <dbReference type="OrthoDB" id="3907302at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016603">
        <property type="term" value="F:glutaminyl-peptide cyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040234">
        <property type="entry name" value="QC/QCL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12283">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12283:SF6">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025091174" description="Peptide hydrolase" evidence="3">
        <location>
            <begin position="24"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="4">
        <location>
            <begin position="124"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8302159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="331" mass="37014" checksum="411FABC8CB36D5BE" modified="2020-04-22" version="1">MVSQFFTKLVLLIGIILSINVTAYSPLSDETLRNLPSGGADFDIHNGAILSPILIPRVPGTPGIQAVQRHFVDFFTKYLPEWTIEFQNSTSKTPVTGDKQVPFVNALTNKWAAMKKAGDVGLEEEKGVQILFLDGEEAFLSWTNDDSLYGARALAETWESTPHAALSTYRNPLDSIDLFLLLDLLGHDKPNIPSYFQATHWAYKGLATLEDRLRKLGVAQSKVNQNFLPDSGRTAFSGGGGVQDDHIPFMARGVEVLHMIPTPFPMDVWHHIEDDGEHLDMPTVEDWAKMVTAFVGEWMDLEGHFPSQPRAEAQKEKRTIISERKTELNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFV4</accession>
    <name>A0A5N6KFV4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFV4"/>
    <dbReference type="OrthoDB" id="48317at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="144" mass="16148" checksum="2245BCF6F55E718E" modified="2020-04-22" version="1">MSNPCSREGQSDVKQRSSGQTKLHPASKCHLQSAMVKPKDLISPLNELKAFFFGCDDYQSCFAECRHLVYQSLLTPLLKSFSSKQKSPIVVQKPGEAIAAEASIPKLRDDYILVNTKAVALNPTDWKHIEWLTSNGARCSYKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFV7</accession>
    <name>A0A5N6KFV7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF8035 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_005635</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFV7"/>
    <dbReference type="OrthoDB" id="5428245at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058348">
        <property type="entry name" value="DUF8035"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26118">
        <property type="entry name" value="DUF8035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8035" evidence="3">
        <location>
            <begin position="289"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="431"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="527"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="431"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="467"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="482"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8302189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="622" mass="72219" checksum="6E78EC3BD4792A69" modified="2020-04-22" version="1">MSRMGDPYRNSSETLSNYGAGRGGGGNRWDTERFASERDRVRFATEREERDSRFLRATAGHARERSYDDVYERRGPRGYEEEREHYEERDYYDQPRFQREREAELGRQRPTTITMERERERERDDSPPPRRAGGRPAFLRRQSSLDTFDRKPLVKYERERERERERDEYGPPARRPDVRPPPLTPVPLPRARGLPPPRRYAERDYEEIKVAEPDFYGDEDFRAYPERIREREIVRRRRRSHDRRGSHERRSHRSHSKESRSTATRSVRSESVSSSDSGTTISVRSEFPKKGKTRMPARLVSKKAIIDLDYPFEEEGDTIIIQKALGRENIDEVIKLSEDYKAAEKLEMSGGRSEAGTVVEERTEVFTIPPPPPSVHATPPPPPVVHHVPPPPPSVYYAPPPPPESVHYAPQPPPTPAQWAPPPASVVYAQPPQPIIYAPPPPPQQNVEMHESTRIVERSPSPARSTYSHHSHHSHHTHHHHDPVILEGRPRSRDEESVFYEKREIIERTEPIGAMTVSRSHSHRKDERSIRAEIKALEAEKEALKADRRANREMRRADRLRREGARHSDSQLVLYEDEIHDGRDVTIVRRERIVEPEGGVRIEKDRKAPPPKLVRAMLATLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFW1</accession>
    <name>A0A5N6KFW1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_005941</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFW1"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000104">
        <property type="entry name" value="ATP-binding cassette sub-family F member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF117">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="195"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8302555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="415" mass="46116" checksum="6DA7C4C11A5B6A20" modified="2020-04-22" version="1">MESDKAESRAATILAGLGFSPERQQFATKTFSGGWRMRLALARALFCEPDLLLLDEPSNMLDVPSITFLANYLQGYPSTVLVVSHDRAFLNEVATDIIHQHSERLDYYKGANFESFYATKEERRKTAQREYENQMVQRAHLQAFIDKFRYNAAKSSEAQSRIKKLEKMPILEAPESVYTVHFKFPEVEKLSPPIVQMTDVSFGYTPDKPLLRNVDLDVQLDSRIGIVGPNGAGKTTVLKLLIGKLSPTGGLISQNPRLRIGFFAQHHVDALDLTTSAVGFMTKAYPGKTDEEYRRHLGAFGITGMTGLQKMELLSGGQKSRVAFACLSLQNPHILVLDEPSNHLDIEAMDALSQALNAFQGGVLMVSHDVTMLQTVCTSLWVCDNGTVEKFPGDVQAYKKRITEQADANGVVQAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFY5</accession>
    <name>A0A5N6KFY5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4-hydroxy-2-oxoglutarate aldolase, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFY5"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF52">
        <property type="entry name" value="4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="37889" checksum="F6D57B2452309717" modified="2020-04-22" version="1">MPFHPPISSALRASSDANSIYSINESSYSSSDSSMSIEDKYPIARPLIPGVYVPTVCFFDPDTQELDTEIISSHAIRLARAGVTGLATQGSNGEAVHLNHAERQTVTATTRAALTSAGFSHLPIIVGCGAQSVRETVQYCVEAFAAGGDYALILPPSYYAPLFLPSSASVIEFFTAVADQSPIPLLIYNYPGAVSGMDLSSDVIIQLSAHPNIVGVKLTCGNTGKLNRIVAATKSPKPHPPASAPHFLVLGGSADFTLQSLIGGGHGILAGLANIAPKACIEMTRLFHEGKIGEAQKVQEIVAQGDWAAIKGGVVSTKAGMQSWLGYGGFGRAPLPHPTSDEMAKWKEGFRELVALEKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFY6</accession>
    <name>A0A5N6KFY6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">40S ribosomal protein S28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_006037</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFY6"/>
    <dbReference type="OrthoDB" id="10607484at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000025">
        <property type="entry name" value="40S ribosomal protein S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_eS28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028626">
        <property type="entry name" value="Ribosomal_eS28_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00961">
        <property type="entry name" value="RIBOSOMAL_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8302673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="12744" checksum="A0224A75911876ED" modified="2020-04-22" version="1">MVWVNWQKCEASRPQSDKSGSRRYVQFNNHIPKSKRINYIAKMDASKVPVKLVKVTRVLGRTGSRGGVTQVRVEFMDDTTRSIIRNVKGPVREDDILCLLESEREARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFY9</accession>
    <name>A0A5N6KFY9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFY9"/>
    <dbReference type="OrthoDB" id="63989at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024905683" evidence="1">
        <location>
            <begin position="31"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="182" mass="20494" checksum="5510ABC11F5209AE" modified="2020-04-22" version="1">MVRPQACGEGVNNLFIFAAFLFVLPWLLDAQQQQRSAPTQYESLPEAVSSEAIRTPLEATKIKTIETPLNVLRRKNTLSLNRGSHDKIDASADSAPLAPSHLAKSSILESNDLQSTGWGSSQPSARDIQDWEVEDFVLLATVDGSVWARDRNTGKQKWRMRKITRNFDDLHQTSQKKQICRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KG41</accession>
    <name>A0A5N6KG41_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AMP-binding enzyme C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KG41"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF28">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="103"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="22271" checksum="CEE1B5EAA99D624B" modified="2020-04-22" version="1">MTEVGMALSCGLSPTDRVDGSVGWPLPTVQVRLVDTETHEVILPGAELDAAGKERDGEIQLRGPTIFKEYWRNPEATQKEHVDDPDGGGRWFKTGDVAVSALEVEREMLSLPQISECAVCAVPSGNWGQKVGAVVVLNEEHLAGKKFGPLDLRRALKERLVAYKIPQVMRVVDHIPRNAMGKINKKELVKRVFVDDMSGDEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KG47</accession>
    <name>A0A5N6KG47_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_006095</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LovG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KG47"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF3">
        <property type="entry name" value="ESTERASE DBAE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="4">
        <location>
            <begin position="19"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8302743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="132" mass="14667" checksum="E77BEFCA3AA78C5F" modified="2020-04-22" version="1">MREDNAKGATGGGRQIREEGGRDLEGQDWKFAVLMAGRAPLISLEKEQDRWGPVDENDVLTLPTLHVHGMKDPGLDYHKELLNVWCDKGSAQLIEWNGNHRIPIKSADVEAVVTPMLALAKKLGVLTVDLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KG49</accession>
    <name>A0A5N6KG49_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KG49"/>
    <dbReference type="OrthoDB" id="7785529at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="110" mass="11963" checksum="DAFDCBF3ED4D18EA" modified="2020-04-22" version="1">MRISTPLMSPPLGPSAPSLSDLTPHPPNVTDDKQELERQRLLAEASAPLEFPEVEEEGESSQQGAASAPDDHEPSAPIFHEEDEYGRGYAHEDFAGLRAGPESLPPSYER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KG80</accession>
    <name>A0A5N6KG80_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KG80"/>
    <dbReference type="OrthoDB" id="5396252at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42068">
        <property type="entry name" value="YALI0B18964P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42068:SF1">
        <property type="entry name" value="YALI0B18964P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="495" mass="53068" checksum="77816A0D5FC12883" modified="2020-04-22" version="1">MTPAQFERYKQDQERLRSVGGRPKDEEAEEEDEETYEDDEDEAEKNKNAAKQRRKQEAHMSVYRQQMMKVTGESTPSPGPPRPSMFNSMSTPNLVLDGATEDGEEEDEEVPLAILAAHGFPNKNKPPTSRLTSVGSNPNLRGAAQAVPGVGGPLPVFARNLPQDPYVGAGLVYPANRESLTFGNGGPGSVNGTPARGAPPGGLVGVIATEERSRAMRRGSPSPGYGQMPPGGFTGMTPPPMMGQMPMGAGALGMGAGALGMGQVGLGAMPQQMLTPGDQAQIRMTEQMQSFMQMQMQFMQMMATNQGGQSTPPASGAPQLGPLGQLGPIGHMSQPNFGELQRPSSQQLPTSNSGPNLRPETAQRTMSMLEPSGMPWMQQHGQGYAPSIHAQGNGYAPSIAPSERSNVGLPGRYRPVSQIPVTDVKARTSTMSGALGGWESKQALTTIKTVQRVDNDDEDDEEGWAEMKKKREQKRSIWKSKKDTSGLSEMLGYTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KG83</accession>
    <name>A0A5N6KG83_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome maturation protein SDO1/SBDS N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KG83"/>
    <dbReference type="OrthoDB" id="2567806at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1250.10">
        <property type="entry name" value="Ribosome maturation protein SBDS, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036786">
        <property type="entry name" value="Ribosome_mat_SBDS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019783">
        <property type="entry name" value="SDO1/SBDS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01172">
        <property type="entry name" value="SBDS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89895">
        <property type="entry name" value="FYSH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosome maturation protein SDO1/SBDS N-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="119" mass="13784" checksum="BD9C909E291FF91E" modified="2020-04-22" version="1">MKASGNQTKIHYKGTKTDEDFIVFVDSEEDLKKWKGDKSIPLAQVVGLFKVFVTHKHGAQGTYDEASVRRGSTWFYAREVRIQERQHGYIECSLEEYLVFTWELTARLGMDGTGWDMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KG90</accession>
    <name>A0A5N6KG90_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KG90"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="126" mass="14413" checksum="3D27D57D5E59EEBF" modified="2020-04-22" version="1">MNITYHWNNLLGYLSGKRNQLQVNRQVQLSKIPESAFKSFVRPFPLFNPIVPEFPVTSSHDVFANLHIMIPTNNHQDSLLCPRHLCDFVCDCSGSGLMCFIRLGFQCLRCVRELADSQGWVNERGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KG91</accession>
    <name>A0A5N6KG91_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KG91"/>
    <dbReference type="OrthoDB" id="422827at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="116"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="282" mass="31187" checksum="47289262DDB97470" modified="2020-04-22" version="1">MSNPLQRSLSRISNRRPSLLPRVDEYQATQTTQPSPPAQVQNIPRESAHTFPETTATASKDPRQPLTLETSIRAYSTTDPWAQFSAPLPAHTSTSTPLPPLPSSTSSASSSPGKDAPSYAGWMKKRRTKMLRHEWHEHHFTLRGTTLAMHKDARALDVLECIDVDDYAIACSSLASSSKLNAAFKRVNIAMGRGGSGDRDKKVDVFSFQLIPQAIEKGVKLKKRDSLMPGGMSGTAGHNNKTHYFAVKSRDERIDWMRELMLAKALKQKSEGYEVNVNGNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHV3</accession>
    <name>A0A5N6KHV3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHV3"/>
    <dbReference type="OrthoDB" id="434986at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="79" mass="9061" checksum="73559A622295A2EA" modified="2020-04-22" version="1">MRPEIPVSNKRLPLSLPKCVLKESQIPNPSFITYSTQPTTSSLNYNLPSLPIFFRTTNQFFNLPIKQSLKTIRINLINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHZ4</accession>
    <name>A0A5N6KHZ4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_004828</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHZ4"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF4">
        <property type="entry name" value="HYPOTHETICAL CONSERVED PROTEIN (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="37"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="963"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="991"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1010"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1044"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1080"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1101"/>
            <end position="1113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8303400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1113" mass="123804" checksum="66A519A5099FC675" modified="2020-04-22" version="1">MFLVLSPPPQEKRDSDVREQVSVPLRKRRGLPKVHSGCTTCKARRIKCDEGKPECYRCKIFFKGTSQKCGYLTRELAKPKSKEAALVTRRNILPKNVEQSEVLLRESIRSFSDIKFESARHFHYFQFFRSDVTTQVFRGFFPELWNRAVLQACHQEPCFLQAVCAIGALSRVMVARKQGRIMTINEDYRFAVQEYGKALDGMKKLIPIRMTLIATLLIFSFENFHGNHMSAVAHIQSAANLLQEWMKDREKRQIMGRYMSPAPDVIEDAVLATFHTTLIRREQEPIENDAADSAIWSKRMLDWSPAMDEFKEILTKLDQWKIAFEPLAKRVAKEDADFVTVCTMRTHWLTTRSSFLSAFIPHTPADDYQSSFEEVVKLCKTVAAHPSFEKGFVFYAGIVPSLTAASRFGAIATRREAIKVLLEIVPRREGSWDAAVSARHAIAVMKMEYEKPKQAARGNTAVVHKASTSSQPHKLYFHNFHTILLHTPSKPTSSIAKMPNWKSYEATVRLLSAIIAAHPGLKLDYAETSKYYGDESSYHQIWKRMAGIKKNSEQLRKAVEAGINPSTVTLEGGVNVMKAISVRFGGDCTVSALENRFKRLKSDAKLINAAVGNGEDPISINVADTNGQNACKSKGAISELMGSETPVGHISSQHRETWKPLSERLIAMRDAGEDCKDVDLTGLGSRRYKAEIAIKMGSDTTAGGIKTQFTRSYKVLAARQDALYAVGKDPKDASLEHLGAHKQPGDISAEVTKYMRSDVTVTGVKMQCIRHIRPLSRHQIALVATGKDPKNVLESPKSETARIMGSDTTPSSLINHFRRTVKILGNRQVSMLAAGEDSKDVSLEMLGLGQSKEIVAIMGSDVTTEAIKQQISKRIKVLGSRQTQMREAGQDPKDVDLEDLMPSKKGKGCQKFYLQHVFFKRHIQLDKLKGDSTAGGIRFQFDTRYKVIAQRQKSMLAVGKNPSTVDIETSGKGKTATAEKYGEGTTGASAKKPRAPRTPSKKSKKAASSSEEKETLNKVKGGRVEKKIVTPGRQAKTGVKNYVDSDDEGEDEDGILIKDEDINSMDFGRAVDGDDDMLGSGFGGRGHGNGRRNGGTIGEAHDEDEDRFYDDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI76</accession>
    <name>A0A5N6KI76_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_004897</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI76"/>
    <dbReference type="OrthoDB" id="206700at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000060">
        <property type="entry name" value="TBC domain protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1310:FF:000001">
        <property type="entry name" value="TBC1 domain family, member 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045913">
        <property type="entry name" value="TBC20/Gyp8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913:SF7">
        <property type="entry name" value="RE60063P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 20/GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="100"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8303480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="430" mass="49045" checksum="5DDF3C2F0BDDCB7C" modified="2020-04-22" version="1">MASNSLTMKSIPHTFIPSILLLHQQMKFDSLTFHTMESDGKSIKREESPAGSRASSRSPSYPTRMKEPREPTKKEVEILEACQWKDLEKIRNLAISQGGLISDDLRRQAWPLLLGCGSDHDDTEGKATSWEDLPKHRDEYQVALDVDRSFIYYPNDQTSKEIEHRKEELSDLIIEVLRRNPYLCYFQGYHDICQVLLLVLPPTTRVPSVARLSVLRIRDFMLPLISPCFAQLNLIPSIISTVSPALCIHLSQTKPFFALSGTLTMYAHDIQEYSDIARLFDVLLAREAVFSVYMFAQIVLSRSEELFQTPTDEPDMLHSILSKLPKPLDLESLIADTVELFQAHPPETLPRWRSISSASVLKTARSPDQITRQSLSDGRRYFAQQVNELQWAAKRSKLLEVMWKYRRPAKAIAIAALVGIISYICLPRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI84</accession>
    <name>A0A5N6KI84_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Eukaryotic translation initiation factor 5A</fullName>
            <shortName evidence="8">eIF-5A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_004899</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the eIF-5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI84"/>
    <dbReference type="OrthoDB" id="9975114at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045901">
        <property type="term" value="P:positive regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006452">
        <property type="term" value="P:translational frameshifting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04468">
        <property type="entry name" value="S1_eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000007">
        <property type="entry name" value="Eukaryotic translation initiation factor 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000034">
        <property type="entry name" value="Eukaryotic translation initiation factor 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048670">
        <property type="entry name" value="IF5A-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020189">
        <property type="entry name" value="IF5A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019769">
        <property type="entry name" value="Trans_elong_IF5A_hypusine_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00037">
        <property type="entry name" value="eIF_5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01287">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21485">
        <property type="entry name" value="IF5A-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003025">
        <property type="entry name" value="eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01376">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00302">
        <property type="entry name" value="IF5A_HYPUSINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7 8" id="KW-0385">Hypusine</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Translation initiation factor 5A C-terminal" evidence="10">
        <location>
            <begin position="92"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8303483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="166" mass="18103" checksum="9B9669F5624D1058" modified="2020-04-22" version="1">MSGEAPVDDSQHEHTFDSADAGASTTYPMQCSALRKNGFVVIKNRPCKIVDMSTSKTGKHGHAKVHLVAIDIFTQKKLEELCPSTHNMDVPNVSRIEYQLLDITDDDFLSLMSEGGDLKDDVKLPDGEVGQKIRALFDSEKETNVIVLTAMGEQLAIDGKEAPKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI85</accession>
    <name>A0A5N6KI85_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">EYC80_004900</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RRN7/TAF1B family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI85"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070860">
        <property type="term" value="C:RNA polymerase I core factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001164">
        <property type="term" value="F:RNA polymerase I core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042790">
        <property type="term" value="P:nucleolar large rRNA transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000469">
        <property type="entry name" value="Polyubiquitin-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048538">
        <property type="entry name" value="Rrn7_cyclin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048540">
        <property type="entry name" value="Rrn7_cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033599">
        <property type="entry name" value="TAF1B/Rrn7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31576">
        <property type="entry name" value="TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31576:SF2">
        <property type="entry name" value="TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20645">
        <property type="entry name" value="Rrn7_cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20644">
        <property type="entry name" value="Rrn7_cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="14" id="KW-0804">Transcription</keyword>
    <keyword evidence="12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="Rrn7/TAF1B N-terminal cyclin" evidence="18">
        <location>
            <begin position="123"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Rrn7/TAF1B C-terminal cyclin" evidence="19">
        <location>
            <begin position="276"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="561"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="561"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF20644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF20645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAB8303486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="718" mass="82723" checksum="1C6541BD3D8FB825" modified="2020-04-22" version="1">MLSDICILVVFALGDLIYKTLVTLIILLGRRRQAGMRDVTTTYSKKKSRTFFNQIIEFLCETFEYGKKFCQRGHEQAGFTQTQQDEDDWNQQGKKSRKRREEKEQVEKVFGGRDATQLYLQCYQLILWKQTHWLVTVKGFPKELETVVRDLWELRLRVLQGSGEERSEYGTEFGSTTEGDDTDTDGTGYRSTASTILSRKRASRAKRNLPKLIETLGFCYLGILLLRLPTSLGEIYQWATRDEIIYTRAIKEIPKDMRTRLPGHYFRALEIHGILNGHRLHQTVLDMIYFYKFNFEMVFPPVNHKLLLYKHIRDLGLPVDIYTAVNHLAGLLQYDFSYPAHNKRLHGTAGYPEYQLISLIIIATKLSQPFDDILRHPESDSDPTAARINWAKWKTIMTEEPSEGLKRGDEIKITDTDVFKMTGAQMDDWMNWYHKTWIDDRDHKVPEQILELFPLPDITSEATVGIVEPDPIDRAKEVHKTLTLQKPVAHTDVNEPRDIVRPGEMYRRYRTIAELPESAQAFYEIAARNIGTSLQKLVYGVFTTEIQLEKWMLDERRKGLSEKEELEGEAEHDQSEEGKYKEDEVEDKHDERDEDSPMKETSATMQIFVKTLTGKTITLEVESSDTIDNVKLQHPKGIHPSLGSPSPWCVTLVSLPVLPTAERRSADTPTNSAQRRSSSKCFALMAFGFTGRLWNGGLVRGCIDGFFAWPALYLRTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KIC3</accession>
    <name>A0A5N6KIC3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KIC3"/>
    <dbReference type="OrthoDB" id="3507418at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="80"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8303452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="151" mass="17777" checksum="AA76B366EE860893" modified="2020-04-22" version="1">MTRKQGLQAFLRKEVIKAKLRIPTEDRTTKFKTKNLTRGAPPDSCEDPERNMFRDIFGDSEEDYTDPLERLRRSKSLFTVNNETKQKTEIRIRIEELRKQLLAVIDTSFKAPRERAIIASERDRLLRSIERLEAQEQRAKDNALRGMWSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKC4</accession>
    <name>A0A5N6KKC4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKC4"/>
    <dbReference type="OrthoDB" id="428260at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF17">
        <property type="entry name" value="(LOVD), PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="228" mass="25352" checksum="591B7CFF204BC28F" modified="2020-04-22" version="1">MVERVNNNISLEEYLRKNVWGPLGIESITFHLVQHPELLSKLTAMSTREGGVNQHGTTTNPEGKAKYTSKVIFDPGTQDCHGGSGTFGSPIDYFKCLQSICANDGKLLKSETIDEMFRPQLSEASRRGLMETLSVPEVNDGMEAFPMGLEADWGLGGIMNLEDIGSRSKGSIAWGGYPNLHWWIDRKSGICGMWGSQLEPPGDPKINQLFHTFEEEIYRRASASREKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KKG4</accession>
    <name>A0A5N6KKG4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_005077</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KKG4"/>
    <dbReference type="OrthoDB" id="10266980at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016814">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052349">
        <property type="entry name" value="Metallo-hydrolase_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32027">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32027:SF0">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="487"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="512"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="536"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="571"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="653"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="8">
        <location>
            <begin position="440"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="692"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8303689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="734" mass="83612" checksum="BFED41F25879BB58" modified="2020-04-22" version="1">MRLTSEAKSRFEHDDLMDRGRALIEESIKFGVTHMRAFVEVDFGVEMKCLDAGLELKAEFRDKCYIQICVFAQDPIFSHDHGSRSMTDLLENAIQKHEVEVLGSTPYVEKSLELQEENIKWTIETAKLYQLHLDFHLDYHLNEHQKPMVYSAIERLHRINWTTNYEHKEFRTVVFGHCTRLTLLDGNEWHKLRQEIRDLPVSFVGLPTSDLFMMGRPDEATGGSIRVRGTLQVIEMIKKYDFNVALGINNVGNAFTPQGTCDPMSLTSLGVGIYQAGTKADAQILLSLRNVYLQELGRRLAFMLNITSTLISTLEVLRVLSFSAQKGHVTLELESQSRSWCMMQDLSERLSLKISSLVSSQYSLYSTTHSEMHDPFPIPPSQWLSQAVQPFADYFHLTTLPLHIHEVLGSFLAYTFINKVVAPQVSIRLFPEKYSKFSAERKLNWDVHVVSLCQSSLINVLALWVMFVDEERKNMTAQERVHGYTGAAGMIQGLATGYFLWDLMITLQNLRVFGIGMLAHATSALLVFSFGFRPFVNFYGCTFILYELSSPFLNFHWFFDKLDMTGSKPQLYNGIALLFTFFCCRLVWGTYQSLRVYQDVWRSMHNQPSSSASINIDALANGTASALDAAAGHSATPIHNDIMRFANDEFIPLWLGFTYLGSNLVLNTLNFYWFGKMIEAVRKRFQPTKEGRQKDKAIAIKSTGANGKTRISVEESEVRRRKALDDNEPIAAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMC8</accession>
    <name>A0A5N6KMC8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Actin-like ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMC8"/>
    <dbReference type="OrthoDB" id="337660at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="48583" checksum="082A74097FF0207B" modified="2020-04-22" version="1">MVCRYLLIDSRPRKVTLALPSTLPSPLLSTILDTIFTNFQAPNISLHSAPALTTVAAGLRAAVTVDIGWNETIVTGIYEFREVLSRRSIRATKLLGQEMRKLLANSFDPKILQQDSPDGQTNVALEEFISFEECEEIVNRLAWCKPSANSTFKTRPESGLAPLQEEDELRANMRSLNISADTSSDAVATIPLRSTLPPRTLTLPFSKLAQPCEEALLATHLPTSELDDEELPIHLLLYQTLLRLPVDLRSVCMSRIVFVGGGSNILGLKARILDELNTLIDERGWDPVQGKAVSQYRNNPKLTRPRRSSSSPTEIPSSPSDTLSSPVSPTTPRPPAHIPAGHRSPEPDSIASTINAKSGKNDTQEERGTVRAVTSLGVWSGASLLSQLKIPAVSSVDREVWMQHGMAGANRNAEVSVVAGAGGRSSMGPGAFKSGIGERGSWTLGLWGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMC9</accession>
    <name>A0A5N6KMC9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zinc/iron permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_004185</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMC9"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF60">
        <property type="entry name" value="FAMILY ZINC TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04010)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="42"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8304848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="36301" checksum="53E68669FEEBE630" modified="2020-04-22" version="1">MSLTDPCLPDFFSQRYHPLTGLVAMFSALVVVGLEMFLTTRGAGHSHSHSHGGKWDAVPSGEDGRVERNGSSNKKGKQPNGRLGKIGLNRRPQSIALEDMGESEGLVAGVSPLPVSTPQPGLTESSERQKYQDGNISDEDSDLELAFDELADPQTKAPIHLPDDAEDITSPISAEDVQKRQILQCLLLEAGILFHSIFVGMAVSVATGPPFVVFLIAIAFHQSFEGLALGSRIAAINFPSSSPRPWLMVLAYGTTTPIGQAIGLIVHRLYDPHSAAGLLMVGFMNAISSGLLLFAGLVQLLAEDFLSDKSYGILKGRRRWEAFAAVLAGGSLMALVGAWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMD5</accession>
    <name>A0A5N6KMD5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_004311</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8305004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMD5"/>
    <dbReference type="OrthoDB" id="2105077at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd13437">
        <property type="entry name" value="SPFH_alloslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000004">
        <property type="entry name" value="Putative membrane protease family, stomatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264:SF19">
        <property type="entry name" value="AT06885P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="BAND 7 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="3">
        <location>
            <begin position="104"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="333"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8305004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="357" mass="38646" checksum="AAD8B2C4C5184E7B" modified="2020-04-22" version="1">MSTSFDGKQTMSDDIHKPFSPPPAGSSSGQQNGYNPSRSTPGRTDNPLVNVQPPRREDLQPSYAQILQGDDDTNTSGWYGSMINALGACIGTLGAIPCCVICPNPYKPVSQGNVGLVTKFGRFYRAVDPGLVKINPLSERLIQVDVKIQIVEVPQQVCMTKDNVTLHLTSVIYYHITSPHKAAFGISNVRQALVERTQTTLRHVVGARVLQDVIERREEIAQSIEEIIEDVASGWGVQVESMLIKDIIFSNELQDSLSMAAQSKRIGESKVIAARAEVESAKLMRQAADILSSAPAMQIRYLEAMQAMAKSANSKVIFLPSASTIGSQMANALGEGSEHHGVSSSRNDTGDFGAWST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KME9</accession>
    <name>A0A5N6KME9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KME9"/>
    <dbReference type="OrthoDB" id="3552010at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="688"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="527"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="713"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="760"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="889" mass="96696" checksum="5F11E0E3B0F41B0A" modified="2020-04-22" version="1">MVGSLTQTPSINTAGFLPPVIPSFMGATQNTLLSVPGGYNMSFVPQGAGVMMNNPFSSVPGATIPTLQTSSSPAEPVAKRHQTGPPGIYGHNPSNLMRSETGRMTLRSSSSINVPDRSMVQLTRSATPNQSASNTTNESLSTEANIIVGLPTRSRSLTPALFATGASSTSGASAAQNPLHPASFLRDTLRASDGPLIVVSPSPLHPLSFHQPTPRAQWPTSHRPIPPSPAYSGSIPGYFQPGQDYNSHGNMGMNMNINTNMNMNMHMNTNMHNMRFPAPSQIGQQYQHNTNTGGQQNRRMPYPYPLVQPNSNEYMMAQAAFDLHSNRSFNGPTTFAPLGIRMNHNLLSQHVDRLEQQQPLTLEASEDQHRLRIAQRIQASLREYNLNAPMPFDGIPPPPLSDDLRMVPRIRKKISNELESERSALAINLLTIGERFECDFCSGPPMPHGIGLYNHEFLPIWGSVGHDWCRECVRTGKDRIPIADADNLDDDSSRPNKDKKGKGKGKGKRAAKEQAGSGPPPKKPIHSSSGSSPMNASGSSAYYRYHPMSDASNEFGDPQEKYSTIDNILINPFMHNLMCRGSQHRQIDMQKVKICERCKVLKLQIIAHRCHTEFSHIIALNDDGQWQMDLHSSNRQAPGSVQFGGSDDMNGGLNSNDLIIDVAADLANGYMTLDAIKAIVAAGMNEGGMSSGNASSSTNDGTNSSMSSNMDVTMSGTSSSGMNTSMSSATSPSMSSNMDFTMSGGISSSMQSASNPASQRKPTNVDSFSTPQTNQPSSSRQFQTAAEASNPHYHNVHMNGKPHGPISKFCMVCPSPSVFLCDGCPLTLCESCRYKLTNTCQGWFNNLVYTNGVNHNRNDAFLLRSDNGGYHEYGRFWPLPARMNFSGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMF9</accession>
    <name>A0A5N6KMF9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Maf-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_004209</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMF9"/>
    <dbReference type="OrthoDB" id="10267058at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213:SF5">
        <property type="entry name" value="BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8304878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="27656" checksum="8BAEC2B48A421E96" modified="2020-04-22" version="1">MCISITITITITITITTTNTINHHHHHHHHHHPSPPTKPKTNPPQIGLTNLEIIPSPLPENLSKEHLGPFDYVLQTAIQKCLSVYTHCLDNSLASIPDPSLVIAADTVIVTNSGVILEKPRSQADHIRMLQRLRDEKSHKVFTAIAALAPRDDARYPGYNCENEVVETKVVFDAEVGDELIEAYVRTREGVDKAGGYAIQGMGAMLVERIEGSWDNVVGLPIRNAVALMEKAVFDQEDLDPEEEGEGEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMG7</accession>
    <name>A0A5N6KMG7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1776-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMG7"/>
    <dbReference type="OrthoDB" id="5308060at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013952">
        <property type="entry name" value="DUF1776_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313:SF1">
        <property type="entry name" value="3BETA-HYDROXYSTEROID DEHYDROGENASE DHS-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08643">
        <property type="entry name" value="DUF1776"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="52949" checksum="384E46E07CF89DA3" modified="2020-04-22" version="1">MSADDQVFLDILSSVPNDVKKYSNDVAEYVERHIEKVAASIRVSLASAEWIPSSARPRPPPPARTLSAPVYTRIEQWVSKNKLLTGAIIIVLGGVTYYITKKRSNYRKKRRAKRAATGARQEVVVIAGSPSEPITRSISLDLERRGFIVYVVCNTIEDEVLVQNEARQDIKPLMIDIVDPSSASSAIDRFTAHLRAPHSPFQGGKTHHLTFRSLILIPSLTYPSSPIATLSASALSDLLNTRLLNPILTLQNFLPLLTQLPFQGPSSSLDAPKPSVLVLTPNIIPSLSPAFHAPESSTTSFLKTFTQTLTSELSSLSIPVINLQLGTFDFSFFGPKNQLQSYRSRSPTTNSDWDPTSRHVYSRNYTAVNSGNVGAAMGCGSIGGGHGKGSSLRELNNAVFDAMERQSGGVVRVGMGSSVYGFIGAWVPRGLVGWMMGVREFKEESAEGFHTSIPESASTSSFEGRELTPESSGLAGSDYISVMDLEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMK9</accession>
    <name>A0A5N6KMK9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMK9"/>
    <dbReference type="OrthoDB" id="271448at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578:SF1">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024922660" description="Apple domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="37089" checksum="5902EB63892A5946" modified="2020-04-22" version="1">MKPVVALSAFLAVATATPFLKPRSLDISAYKAVTTAPVRGAPAGNTATASLKYNPTSVANAAIAAATSSAAIVNRRNKRSTCPSTCAVLSAGNGPSVNNPDTAAAFEADKNLANAALKAVTPADYVLVDGFQNIDSAAQSATYLTYVSDSVTSYDPAICANACNAIQGCIAFNIFFERDPTLVPDTEDCPNPPSQTLIKCSLFGGLLDALLATNCGQWQADFQVVIAGSNAYNAVTPPSIPGYRGVQSFGSATIDAPANTTTYMGVEAFSQTQPYDPTVCAAACSSKSNPGCAFFVSYILYENDQNGVFTCTYFTVPYGSDRAIETGQYDNQGNHYTIGHSFGFTVDGYKPSRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JRH9</accession>
    <name>A0A5N6JRH9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_010052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JRH9"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845:SF6">
        <property type="entry name" value="BETA-ALANINE-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845">
        <property type="entry name" value="CARRIER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="3">
        <location>
            <begin position="47"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8291372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="523" mass="57414" checksum="E8A5C6D4C1651C5D" modified="2020-04-22" version="1">MKPTVIVPTKLIPTTPNGKTDRVAVDKIPVPGPSNLNTTKKPTRALDCWENSIKEIWEEILSSRMAHTFERSQSRIDHNSDFFQVGGSSILMIKLKYLLEMQLGVKISMPELFHTSSLSSMAKLVADAKAAVNGTASLPTMPSFLGPKNIAQVIDRDLEIATIVDKLSQPRAIPSLSIESSLSCSEKLVVVLTGATGFIGKHLLSCLVQSPKVGQVHCVAIRPDASGKPRRVAVNSDKIVEYTGDLSDSNLGLSAAQFTFLAEHSHIIIHNGADVSLLKTYQSLRRANVISTRTLCSMAILRRLPVHYVSTASVAKVIQQKPLLEVPASPADADLLNSVDGYAASKWASEALLAKIAVESGIPVYIHRLAHVMGEDASELDAVGMMTKYSFLLHALPRIKEEAIEGQWDFVFVESVVDELVRSAMKSAIDYGHPSTSQSKREENRPAVFINHCNDVTIPHCKLKGYLEATSGEPLGEIELKEWLQLARETGMHPLIYEFFLAFEQGRGKMTLPMMSKTQRVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JRI5</accession>
    <name>A0A5N6JRI5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">acyl-CoA oxidase</fullName>
            <ecNumber evidence="6">1.3.3.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">EYC80_008328</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2</text>
            <dbReference type="Rhea" id="RHEA:38959"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.3.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; peroxisomal fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the acyl-CoA oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.6" evidence="6"/>
    <dbReference type="EMBL" id="VIGI01000016">
        <property type="protein sequence ID" value="KAB8290687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JRI5"/>
    <dbReference type="OrthoDB" id="538336at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003997">
        <property type="term" value="F:acyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033540">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA oxidase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000015">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000003">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055060">
        <property type="entry name" value="ACOX_C_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029320">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF250">
        <property type="entry name" value="PEROXISOMAL ACYL-COENZYME A OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22924">
        <property type="entry name" value="ACOX_C_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14749">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-coenzyme A oxidase N-terminal" evidence="15">
        <location>
            <begin position="31"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="14">
        <location>
            <begin position="147"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-alpha1" evidence="16">
        <location>
            <begin position="288"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF22924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAB8290687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="446" mass="49514" checksum="0D16882F85B5CE0C" modified="2020-04-22" version="1">MSPPQWVKDLKPSGPQGTELIEAERKKSNINVEKLSNFLFTKEVLERQEYILKILQADKIFDKSNNYFDGRVDRFKTSLARAKRLRQLQVKHNWSEEEYHVANDLISEPTPYGLHSTMYLTTLRGQGTPEQHKLFLEPAENYKAIGCYAQTELGHGSNVRGLETTATWNPEDKTFILHSPHLTASKWWIGSLGRTANHAVVMAQLIIAGKPYGPHPFVLQIRDMKTHEPLEGVYVGDIGPKFGYNTMDNGFLLLNHVKIPHINMLAKFSRVDPETNKYVKPSSPSLIYGTLTWVRSTIVLQSGGVLARGVTIATRYAAVRRQFQDRDSGPDAAGENQVINYTMVQYRLLPLLAATFALHFTGKAMMGLYQDNQARMQQNSANVSDSNRGAGPEELNSGSDLLADLHATSCGLKALGSTTAAEGLEVCRRACGGHGYSSFSGIGTCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JTL7</accession>
    <name>A0A5N6JTL7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JTL7"/>
    <dbReference type="OrthoDB" id="5216128at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025363">
        <property type="entry name" value="DUF4267"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14087">
        <property type="entry name" value="DUF4267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8292422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="146" mass="16272" checksum="4DE7A31F97FC96EF" modified="2020-04-22" version="1">MNVLTDPYVYIGNQTFISRTLKSSSNLNSITFSRILRFLPNIFGTIFIGFGINVLLRPSHALTFYRPFSLPTAAFDKALVAAFMTIYGARDIFMGLAMHAASYYRNYRTLGWILISGSGVAFVDGWVCYKAGGASRSLGFWIARAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JTN8</accession>
    <name>A0A5N6JTN8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_008164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JTN8"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8292442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="75" mass="8946" checksum="B2E9BB9F44989E6E" modified="2020-04-22" version="1">MDCIGPPLLVFTGIRMAFLRYGWMEGVIAEDYWLEGKKFYTREFWWRISWSQYLGRELGNVVESKVYNRIGDGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JTR6</accession>
    <name>A0A5N6JTR6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">V-type proton ATPase subunit e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_008184</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase e1/e2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JTR6"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008389">
        <property type="entry name" value="ATPase_V0-cplx_e1/e2_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05493">
        <property type="entry name" value="ATP_synt_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8292468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="13467" checksum="44AD11A95E728338" modified="2020-04-22" version="1">MYWFQQLDWFNSHMITRVARTTALSNSQSRNPDLPITAINMANGWSIVIGLIIVVLASIAAWFLSPKGETQTIWRSSLILSFASCYIMWAITFLAQWHPLIVPRRGDLRPEYARHMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JTS1</accession>
    <name>A0A5N6JTS1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_008188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JTS1"/>
    <dbReference type="OrthoDB" id="3930719at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8292472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="142" mass="16322" checksum="39A8C8D2A6E1D5FE" modified="2020-04-22" version="1">MKTYQCFDKTSDWWFCGTCGVRPFAMGLDFRNGEIRKVNLRETGVTEANGKEVSEGETEVWMCPKEGKGVDGKTVEWEEGKTGYLSVNATALEAGQEGCDLREWHEKGWINYLDSSLINWSKNHRMQETFHLIFQIYSLAHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JTT2</accession>
    <name>A0A5N6JTT2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JTT2"/>
    <dbReference type="OrthoDB" id="2391627at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019182">
        <property type="entry name" value="Cytochrome_b-c1_su10_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254:SF1">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09796">
        <property type="entry name" value="QCR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8292483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="150" mass="16699" checksum="57D391A47E50DCA2" modified="2020-04-22" version="1">MIKIHGDYIIKPEAITIIPTNPDKHSQSRIYPQTSRLPLIHHQHTLLFKMGSNGDFHASTGVTPPKGPVSYSTYKSPYGPKYKIQPHIAGWTPKAASKVGLTLAGFGASAGFFALFFFSDIPRVRNDIMVKIPIIGDRWRREIPASDNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JVV0</accession>
    <name>A0A5N6JVV0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Exportin-5 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8292990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JVV0"/>
    <dbReference type="OrthoDB" id="2215036at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042565">
        <property type="term" value="C:RNA nuclear export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045478">
        <property type="entry name" value="Exportin-5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF3">
        <property type="entry name" value="EXPORTIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19273">
        <property type="entry name" value="Exportin-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exportin-5 C-terminal" evidence="1">
        <location>
            <begin position="311"/>
            <end position="1126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8292990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1175" mass="132081" checksum="7621646E63F84523" modified="2020-04-22" version="1">MNGSTNGHSTTTNEVPAAQTNGNTALLSQIHEALELVHSPYSSNQSRQQASNFLDSIKAEDEAPYHGFTLASDKSQQPVVRHYALSLLEHAIKHKWAAYSEAQASALRLWIIQLSEDLVQEDPLYLRNKTAQLWVEVAKRSWGSEWTDMDELLVRLWELPGPVVHKEFVLFVLETLSDEVFNGEDAVTVLREGALSKACVEIFTPTVVLSEAFPNRQLGTVLRHGGEGWLVRIGALLGQCLQLDISSPQYQSCAVKILAVYKSVVPWTLPKAISSAQCVQYMCKCLAASSTPVQLMMSNLGVFIESKISALPESCDLSNLLNLFLAIAQSQSLVVSIPIILTWTKLLRSPIIGSSPTITPLIAPLLELCSSRLIRYENMPDNCEDPEYLFLKEDIDTQPERHAFLGNYRRYCSQIIELVVRQKQSEALYHILGQVDSSLQHLYDGCPAFSIENYSKTSIPILRVDKNFTVVEASLKGYMKWRGSHGSEPQRDEQERTSIENNLETWGERLLELKFEDPIITKRIIQLAVAFSTTALDKKVGFMLKVLEHILMTQPMEYPNTPTYTEAVKELQAESAYELQRLAGKMPNQLLDVYDQLQAKVNEIISTRNLDKKRQTSYQTFLFTIIHRTSKIEPEMSWQDSEMNSAIQGFSGFCNLLGLNRVRDFLVTRRVHEIQDWSAYQLDSEAQSIQKDMEERLKALPLRTTKSFLGCSTEKMRKDDPAYQVSCDLWRDKLPIILPNLLKYLSHAHAFHNPANWNELPPEMAPIVSRILTDRFWQAGISVGSKDDFYARVSGTKSTMEGLASSIRGSIRTVRESCYSILFSMSSLDVDFYGFSELPGPLAHALFADAHCLSSHQLIALLNIVRLLVDECPVEVRSHFVPPILASCFTQMDAKCSSEWEKLSHKNVVPADEDTLTEEMKEESILRQLTHTSVMMVAGFLDPARPNIGSAPSPRSAKEASTFIQTQANAYPSMRKFCLTSSTILEPLLLFLTHAIRMRDTRCCGVVLRVFRSIVPDFASSDDSPLSSSIREFISIEVLKAAISSLNEPYFVELQKDLAHLISSILIYYAPLTGTPKQILLSLPGIQEKAIDKCIDSLQKQGIQQRQQRALVLYLLKDLKGISISEQGRISKSASVARKERSKMQEAFMKGPVEDDKKIKSEIDDLEGVAGLFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JVX6</accession>
    <name>A0A5N6JVX6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_007405</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JVX6"/>
    <dbReference type="OrthoDB" id="47494at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF1">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="20"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8293043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="395" mass="44044" checksum="38D5CBE23B5F4FCB" modified="2020-04-22" version="1">MTFSEVITKEGEGEAKAPNLKVLIVGAGIVGLTLAQGCRENGIEFEIVERDETGKRAQGWAITLHWCLRSLERTIGKRLSELIYTATIDPTLNDVDGNFLFLNARKAEPRYKIPPSKQRRRLDRQKFRNLLATDLNVREGKKLSSLTPLSESDPLIAYFSDGTQSSATLVVGADGNNRIVRHFTEEQIEPVRAIDPLLFQSLDPETGTFMWFSLQGITENPDASKSYKGLVIVSWLIEDDIKDAMPKTDKERVAYVKRRVEGYAEPLRSIVQDIPDDVATTPLRLGDWPCQEWDNWGGRITLVGDAAHAMTMYRGEGANHGILDAALLIDQLKRVKAGKITQKEAIYAYEAEMRPRTHEAVLKSRQAALDAHDWDALSESSPAIGGRIAPKTAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW25</accession>
    <name>A0A5N6JW25_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">EYC80_007481</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW25"/>
    <dbReference type="OrthoDB" id="10254238at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000014">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12 13" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="15">
        <location>
            <begin position="38"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="7"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAB8293125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="139" mass="14882" checksum="DB7F478230D47ED4" modified="2020-04-22" version="1">MPPKGVASKAPAATKAPASASKVPAKQDAGKKTTTGEGKPRKKKGRKETYSSYIYKVLKQVHPDTGISNRAMSILNSFVNDIFERVATEASKLAAYNKKSTISSREIQTSVRLILPGELAKHAVSEGTKAVTKYSSSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW29</accession>
    <name>A0A5N6JW29_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_007488</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW29"/>
    <dbReference type="OrthoDB" id="1924260at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF29">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="9">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="18"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8293136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="403" mass="45791" checksum="24741D6DDE79E852" modified="2020-04-22" version="1">MMLPPLLFSQRRLSLRNKTCSKSPSGVTTEPSENDTVTHEVPGEQSAMGNTARRSRHSEKKIQKPESEIIEEVMKPLTDDERKAWKGWCELESDPTTHNSCATIALLNIIMNVPDLDLGENISSFKEVTQLLKPAYRGQKLSENEYIRNLHNSFARRMDILNADLALSNEVSAWKKRRKMKKKPGRNKAKSDEEPGFHFIAFVPIEGVVWRLDGLQRQPISLGEFSDDWISVARTNIHQHISKYGDGLQFNLLSLCRSPLRTIPLKLAQNIHAINLVEVMLSQQTPDWNKFSQEDVSEPIRGPSDALGVTDKLLHETVLPASTGKILEQASTDASILLLLRQQWVAEQRELRITYMDELSSINEENEQAARRKKDHTPLVYRTLKSLADKGLLKQIMEEVQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW30</accession>
    <name>A0A5N6JW30_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoporin POM152 Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW30"/>
    <dbReference type="OrthoDB" id="5529162at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070762">
        <property type="term" value="C:nuclear pore transmembrane ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056541">
        <property type="entry name" value="Ig-like_POM152"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037701">
        <property type="entry name" value="Pom152"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28206">
        <property type="entry name" value="NUCLEOPORIN POM152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28206:SF1">
        <property type="entry name" value="NUCLEOPORIN POM152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24312">
        <property type="entry name" value="Ig-like_POM152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoporin POM152 Ig-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="103" mass="11697" checksum="5157CC5A4158CB10" modified="2020-04-22" version="1">MPSVKISKGRQVEVDIHEGGQAELLFEFWGVPPFEFTYTRSTNAKKGQKSHVLETRHEISYEHSKIIQSSQEGTYEVVAIKDQFCSFSTLKADGKSGQKLLQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW31</accession>
    <name>A0A5N6JW31_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 18">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="5 18">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16 18">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">EYC80_007495</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 18">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="17 18">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18 19">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="5 18"/>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW31"/>
    <dbReference type="OrthoDB" id="448573at2759"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006659">
        <property type="term" value="P:phosphatidylserine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1760:FF:000022">
        <property type="entry name" value="CDP-diacylglycerol--serine O-phosphatidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016271">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF61">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000852">
        <property type="entry name" value="Phosphatidylserine_synth_fun"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 18" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 18" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 18" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 18 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="14 18" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15 18" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 18 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00060701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR000852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAB8293144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="241" mass="26257" checksum="2C21DDC6FC79E5D8" modified="2020-04-22" version="1">MSKRNSNNAANGATKDSTVGGPAEDKQKRLLEKDTGHFSMIKMLHLADLITELNGFCGVMSVFSSMRYCLGPHDAYGNLWAALAFMPFGLFFDFMDGKVARWRKKSSLMGQELDSLADLVSFGISPAAAAFAIGLRTPVDHFFLAFFVLCGLTRLARFNITVANVPKDATGKSKYFEGTPIPTSLSIAALMAYWVSKGWVLDNIPLGTVGAGTVFEFHPVVGLFVLWGCMMTSKTIHIPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW73</accession>
    <name>A0A5N6JW73_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW73"/>
    <dbReference type="OrthoDB" id="1049195at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="131" mass="14906" checksum="085CD066481BC4FD" modified="2020-04-22" version="1">MAMGMGMGMDMGMDMGVGIRTTHGTPSFFSRTTSKEKSDPCESHLVGQRKAPESRREIKQRFLLLVIGPKQQEEKKKKKKQTLCNCALVIALLPYGSQEPYQIFFTKLHWFTLFTDFDQLNVTFNSPLLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW82</accession>
    <name>A0A5N6JW82_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW82"/>
    <dbReference type="OrthoDB" id="1049195at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8293186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="70" mass="7903" checksum="33579D30C23E8A22" modified="2020-04-22" version="1">MLWIPKSLTSHKIKLCETESVRTNGTKLLRQISNMLQHTLFFLLSSISLCVLKTSNPPKSSDVEDSTLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW92</accession>
    <name>A0A5N6JW92_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C-CAP/cofactor C-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_007544</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TBCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW92"/>
    <dbReference type="OrthoDB" id="194775at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.70:FF:000017">
        <property type="entry name" value="Similar to tubulin-specific chaperone c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027684">
        <property type="entry name" value="TBCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139">
        <property type="entry name" value="TUBULIN FOLDING COFACTOR C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="4">
        <location>
            <begin position="165"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8293203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="362" mass="39214" checksum="4E7BB5714D7015A3" modified="2020-04-22" version="1">MEKTIPAVIRAPFNQSAGSSQDVKERFYRHFQEEVTDLQERIGQLTNLSLVGGERQDATDHCLATLSENLQEAKSKAAPRTKFRFTSASKNSSVVSINDAAQLAQQSLGATNLKSSLLSSTESSMATTPANVMTPPGEDSARDTVGDLPSFPKNYNTEMANAPGPIRKPSFSEASTINITGHNGLHIILPSSASRATSSGAITKLNRCIVDMSIPTANGAPFAGLALKNIKHSLVIAGHVAGAAHITGIEDSIIVVASRQVRMHECKNVDIYLHCASRPIIEDCSNVRFAPIPESQNVTDGSVKNQWDQVDDFKWLKVEHSPNWSILPEEERLKEEIWKNVVPGEPGVGLDDILKRIGLTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW99</accession>
    <name>A0A5N6JW99_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW99"/>
    <dbReference type="OrthoDB" id="5397087at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="348" mass="39169" checksum="4F89AAE774AA4C70" modified="2020-04-22" version="1">MEEPTDPKMTMEMSLYIQTTQSLPSQQQLAEQLSHEQICTKDLARQLLTQQYHYQQLEYRFQQLQRQLTEQSHRQSASGGFNAPLMSQVPTAGPGQKMAEDVKKLQKAHQQSASTSAELCEVTPPPQNMPTPSMSRNSSFEQDMSSPVLKQMPSHGPYMTPMSREESNQSQKSNRTRLVPSPPSSTDQNQDASPSFCQPQSSPRLQQNRHQHQQGLYPNVPEHSISQMPQAETQTIGNYEQLPLRRFLQERATYPATFNISLAQNVDDGFGQFSNGNFETGKNLEDVVFNDWFDFGNNGMPCLAGDSGVHTDTAKMGTWPDRIFGKIYPSTTALELMIAWTGWDISGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXU2</accession>
    <name>A0A5N6JXU2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_009440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXU2"/>
    <dbReference type="OrthoDB" id="10027144at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02394">
        <property type="entry name" value="KH-I_Vigilin_rpt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="2">
        <location>
            <begin position="37"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8293973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="117" mass="12487" checksum="D72C3E78BDE04BCD" modified="2020-04-22" version="1">MKKTHLMMLRNGSSSTSLILERPSLLAQAIEQASKNNFVGHLTLVDPSLYGSIVGKNGSKVNSIRQATGCNVTVPRGQGTDPIEVVGSEEGIQRAKELILQAVAEGKNKPARGGDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXU4</accession>
    <name>A0A5N6JXU4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_009437</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXU4"/>
    <dbReference type="OrthoDB" id="5325318at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050085">
        <property type="term" value="F:mannitol 2-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019594">
        <property type="term" value="P:mannitol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000090">
        <property type="entry name" value="NADP-dependent mannitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF103">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8293966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="354" mass="37290" checksum="625BD9F780B7B8C2" modified="2020-04-22" version="1">MSAVRSSIVRAAIKAGRRTTPSIARQAVRAFTTTPQANDYEAIHEKEIPATKFQPGSGPERVTIPVEEVAAAAAKETVDVVTPLTQSAYKGMTPTMQKMSLMGKVVVVTGGARGLGNHMARACVEAGAKALVIFDANQELGDASAAELYELTGNKIPISFFKVDVRDADAIESAVNSVVAEHGAPDVLINSAGIADSNIPAETYDHNMFRRLIDINLTGSFLMSQAVGKAMMAAGKPGSIVLVASMSGSVVNYPQEQSCYNASKAGVVQLGKSLGAEWAKYNVRVNMISPGYMDTALNNVPALDAQKVIWKSLTPQNRLGAVDDLNGLAVFLASDASAFMTGSNVIIDGGYTLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXV9</accession>
    <name>A0A5N6JXV9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinase</fullName>
            <ecNumber evidence="4">2.7.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_009455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="4"/>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXV9"/>
    <dbReference type="OrthoDB" id="2573163at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000824">
        <property type="term" value="F:inositol-1,4,5,6-tetrakisphosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008440">
        <property type="term" value="F:inositol-1,4,5-trisphosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.160">
        <property type="entry name" value="Inositol polyphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005522">
        <property type="entry name" value="IPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038286">
        <property type="entry name" value="IPK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400:SF21">
        <property type="entry name" value="KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03770">
        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="104"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="507"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="583"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="656"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="321"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="598"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="663"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="687"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8293989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1133" mass="125592" checksum="A8420914B7898B3B" modified="2020-04-22" version="1">MREPKERGTSLERTAKEKRVQDLPKGSFSTNPGDTGIITRPSTPLQEPVGSLSNTPPVDGIRASYRSWRDARTSPPVEKAWSICEQGDDDQGGQVEKAIAEALSGVEHNNRSRKASHSLRFFREGLPEDKTKKRENKNRAQPKDAGSSARIGSIPEGGKLETGTHSAVGLEGESLSPFADLKMASKSPTHNTDLNPTSSSNEGLSAEPDYFDPSRGTEALASDKVRRMPSQLLADIRKHHNLTPGNAKGSSFSGSIPAPESEKSKADSGEENLGGGSQLDREGNEDGADLEMTKSRDDGNESGEEKISSALFVPHKTAHGTSERRGEGPRDRLDLVAGAGDNDQLQSEDSDPQQWLEEHRVPSCEIENPYDSQEDTHDHSQDSFDEGESTTYEESLTDDPEATPTSSRYRRPSFKVPPTPKINVIEDPEEARKSRGSVELIPYKHQVGGHTTMWRFSNRAVCKELNNGENKFYEICERKHPQLMKFLPRYIGVLNVTLEKKHLKPKVVPKDEKDALAESNVTDGHPPKDETTSADTNGHTTSEKPPEPTRMISQSLRTSSIPIATVNFADNRHIIPKSFLQPHPHLIDPIEAPSTKDSTQTTQRGQSQSQPPPSGDFTFRPTLSNKHAVSWGATTVNKELRNKVFGEAFLQQPIPIYRHKKPGSQSRTLRSGSSLRSASSEVGLKTHKSEPPKDSIRTRAMKTAAEQRTGLSPMTPITPAPPVSTNDGDVNGNAHCENGDVEDEFDNMAGTSAPEAEIVGPQDSPKRPKRRYSSGGLRRKPAEVADGRGNLKYFEEADDAGYKGDEEDVFTMDPESTGEQKTLPLSIKKETTPKLEAVKESSELKSADSDAIVKRPVMPKILPSALVIPPRPVNPKEAQTQGQRIQYFLLLEDLTAGMKKPCIMDLKMGTRQYGIDALEKKQISQRTKCEATTSHDLGVRVCGLQVWDVKTQKYVFHDKYFGRDLKAGPDFQKALTRFLYDGVDDGSILRHIPTLIKKISTLEVLIRSLPGYRFYAASLLLFYDGEMVEEEESDSNAFEPLSRRREIDLKMADFANCAIKEDCLAPGRHCPPRHPDQPDLGFLRGLKSLRKYFLAIQKDVRENLGIKARDWGDDQRKIDLEDEYDEDEANLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXZ9</accession>
    <name>A0A5N6JXZ9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Crh-like protein</fullName>
            <ecNumber evidence="15">3.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">EYC80_009478</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Dual chitinase/transglycosylase that plays a role in cell wall architecture. Chitinase and transglycosylase activities are coupled. Required for the polysaccharide cross-linking at the septa and the cell wall. More specifically, transfers chitin to 1,6-beta-glucan in the cell wall.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the glycosyl hydrolase 16 family. CRH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.-.-" evidence="15"/>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXZ9"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06923">
        <property type="entry name" value="ChtBD1_GH16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000159">
        <property type="entry name" value="Glycosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017168">
        <property type="entry name" value="CHR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF22">
        <property type="entry name" value="GLYCOSIDASE CRH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037299">
        <property type="entry name" value="Glycosidase_CRH1_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8 15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 19" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024854409" description="Crh-like protein" evidence="19">
        <location>
            <begin position="17"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="20">
        <location>
            <begin position="58"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="356"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="376"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="16">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="16">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00093308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR037299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR037299-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAB8294016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="486" mass="51006" checksum="6E53C4F3C760E187" modified="2020-04-22" version="1">MVGTSTFLASLASASAAFSATCSLDSHCPEDAPCCSQYGQCGTGAYCLGGCDPRMSFSLQSCVPEPVCQSASYTFENLDGITSNTKYLGDASKTNWVYSGNPVIYNDNVLLTMARDSVGTVMASSTYMWYGNVKARFKTSRGQGVVTAFILFSDVKDEIDFEFVGSKLGTAESNYYFQGITNYDNEQDITLSDTYANYHDYEINWTPDEITWLIDGQVGRTKKRADTWNATANQWNFPQTPARVQLSLWPAGLATNGEGTIEWAGGVIDWDSEDIKNNGYYYASFESVEISCYDGKSAPGTNSGKSYYYNNVSGTNNTVVDSNNATILSSLLGTGTNLTAGASAAASGSTAVPTAATVPGLTGSNGGGVGDDHSGDSSSDSSSGTATGSSSSASSTGSSGFSQGDDSSSSSSSKSSADSLGANQERVLKGSIFAGVVAVVAMMALGFGAFAFSEDSLGIGMGIYLHYNGLKTFYSFCFILSPSRYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JY68</accession>
    <name>A0A5N6JY68_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JY68"/>
    <dbReference type="OrthoDB" id="5426978at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8294078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="146" mass="15791" checksum="5405886F355E4C35" modified="2020-04-22" version="1">MRSPLIHYFKTFAALALPNLLQFEETKKDAEATLKTFLEGRLAASTWDNSIREYLITNLETQRRLSISQSQAQAQVITQQPTGTGANAKADDNQNMITAANQGLQRLADLATASTEDRSEGPTSSADSGARNDKDASFPAAALGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZY5</accession>
    <name>A0A5N6JZY5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein EFR3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_007042</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EFR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZY5"/>
    <dbReference type="OrthoDB" id="19232at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039786">
        <property type="entry name" value="EFR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049150">
        <property type="entry name" value="EFR3_HEAT-like_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47766">
        <property type="entry name" value="PROTEIN EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47766:SF1">
        <property type="entry name" value="PROTEIN EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21072">
        <property type="entry name" value="EFR3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="604"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="805"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="886"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="604"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="817"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="905"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="933"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="972"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1013"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1046"/>
            <end position="1062"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8295106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1110" mass="121325" checksum="F826977DA6710F20" modified="2020-04-22" version="1">MHAIRQKCRPKHQVLILKCYPKTTKGAVDVKPNSSELSYLLFYATTRRSKVQKVGEFLEKKTASDVWRARIGNVQVTLQILAALIEKAPRDLPLYAPYVLKILNIVLRAQDVTMVESSIPTFQAFCENHDMATLSAEQEYLHQYEEIVQIYASFASTRTQTATKAQSAPVSIRWRSLGLQAVKSVASSQALSTVAGRQLDVIVPILLENIWTDNEDFLEILQQRAESEENAGTEKSFLKRRASNATVQTVDTAGENPTALSGTTADADKLAEENIGVLAMQCLKQIFVVNNRSQIHGATTAVLKFISDRVNLQESVIKNGPNENCKGWGPQIFEMIARWTPVQDRYVILVTAMDSLVQTDQIEATLMQQLVLATMVDSLLKSDINLIGLSVMDVLLGLIQHILIALQLGNVGGPHLQPDNGVDEKNDFDTLDAPITSETALVPTDTRKDLLARLQNCIGDLATHVYYADQISDMVSAILLRLKPSPSSPVPSTVAAIEDPNSATEALLSGTNMTEDPNTDGFFSFDTAKIKALESIKLILLVASQRTMTAGNLGRNRVPIKTWEGTQWLLRDMDGRVRKAYADALLTWLEMEVTRDDQRVFDEKPKGLMKSARDESSTNLAKRVASNASKPEKPSRSSRSTFLQLLHLAIYENAMQFVDYENDIVLLHLLLANLIKNLGVNAVRSGLPMVFRLQEDIVSFELPVHKIRIGSLCHAYFWTLCEKFEIETSPAGKTVQDEIHQRQKAMFWVDNIRFPPVQLHNIGTPGRTSSQQRQSTNYAGADALSPFDDRFQMVKLISLSYAASINSPPSSPPTSPGRSFTHPTLSVDISTSTRDAVVPEKIKEEMMSEWNKESVIAIAQESSRTASISGSRAGTTTTRHRNFLAINGLGNGSNSGTASPIGGYNSRSGPNSTFGTTSGIGAMHKLRKGGGNSSAPTSESSRGSVTRVDHLKRVLSGQSTALPGTRAGAPQSDASSESMQNASGVERSASMRSAGRSRSKSRDRVPSYMERPLTSSPSDVAQDGTTVPPVPPLPSSLVGEQVSIHDQAHNHSPESYRPDRGTKRSTKSRAGGYPSMPWGEENGKVVDLQDLLSGIDVGGGEKGNVGMPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JZZ6</accession>
    <name>A0A5N6JZZ6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_007037</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000010">
        <property type="protein sequence ID" value="KAB8295101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JZZ6"/>
    <dbReference type="OrthoDB" id="333239at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16104">
        <property type="entry name" value="Ubl_USP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="4"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="108"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="259"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8295101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="288" mass="31454" checksum="87A9B1A0954DA0AB" modified="2020-04-22" version="1">MATIPVIIKHQGKKYDVDLDPTSNGETLKYQLYSLTGVEPERQKILVKGGQLKDDTDLSKIGAKPGQTFMMMGTPAEGGTFSRPKEAIKFVEDMTEAEAAQQIGATPAGLQNLGNTCYLNSSLQTLRVIPELQEALQKYRPDGSNDSNLLGGFGLGPMDLTASLRDLYKQMSETQEGFPPLMFLNALRQAFPQFNEKAKNGHGHAQQDAEEAWTQILQVLRSKLKIKNEGGILGGSSSAEVSFVDKYMAGAFKSVTECDEQGAKDAGEQPWRNQSSSRWNCGRIGGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1K0</accession>
    <name>A0A5N6K1K0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">60S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_008840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8296030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1K0"/>
    <dbReference type="OrthoDB" id="268693at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00513">
        <property type="entry name" value="Ribosomal_L32_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001515">
        <property type="entry name" value="Ribosomal_eL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036351">
        <property type="entry name" value="Ribosomal_eL32_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01655">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01393">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52042">
        <property type="entry name" value="Ribosomal protein L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8296030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="131" mass="14964" checksum="9F34255FBA837321" modified="2020-04-22" version="1">MVSAKKHVPIVKKRTKRFHRHQSDTYKCVDASWRKPKGIDNRVRRRFKGQMVMPSIGFGSNKKTRHMMPSGHKAFLVNNTSDVELLLMHNKTFAAEISHAVSSRKRVEIVARAKELGVKVTNAKARITTEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1L8</accession>
    <name>A0A5N6K1L8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminotransferase class I/classII domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_008730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8295909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1L8"/>
    <dbReference type="OrthoDB" id="65434at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017059">
        <property type="term" value="C:serine palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF3">
        <property type="entry name" value="LD36009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8295909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="12779" checksum="8CFF28F9E159EAB5" modified="2020-04-22" version="1">MPAFSHEMLRRKISVVIVGYPATPLISSRARFCVSAAHNKDDMDRILAACDEVGDVLQLKFSTGVAGGAEHLPDGVTPEMEKEWQKANGLQGVVKPPRWSLREVIANGVADVKEPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3I0</accession>
    <name>A0A5N6K3I0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription regulator Rua1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3I0"/>
    <dbReference type="OrthoDB" id="5595379at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028012">
        <property type="entry name" value="Rua1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125:SF3">
        <property type="entry name" value="TRANSCRIPTION REGULATOR RUA1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14616">
        <property type="entry name" value="Rua1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription regulator Rua1 C-terminal" evidence="2">
        <location>
            <begin position="467"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8296863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="637" mass="71487" checksum="E250333022AA3D64" modified="2020-04-22" version="1">MDPSLAQSRHSFQTQPSFTFNPNNKFRRDCPPRSFPSASTMNPSEMSMKQEPIGLGMWSTTTPPNSITRPRPATIHETGFSYCMPEQNNYSLPAWDSSTMPMQPVHDGLPQSYAVHQDFYSPESVGEREPHQNHVMPLSGKAFSDFDFTDHWNTKICDDGMEMQSIDTEMHMGQAYTTDEAVPILDLRCGSGMDSERPSMDQPWGSRRMSGSSFTLSTTGALSEMQSYEDFSATLSEAPSFSSDYPPASNRNSVMSSTQLSPVASPRMTPQSRPELVRTQSRGRASPSPRPSMRSAPYSMDSNRNKRWSTGSYGTAPSRRPSPFVYHQSHESFPPPHPPHMSSRHSSPTITNPHLPLNMTNLQTQQYPFMMASNTAYNQNSMLLTSHAFHEPHQFDTPPPLLSHGLFRMLQSNADPHSLHTHYSDLSDPPDLYASLHEEQLAPPPEDMNPSDPDLIPHEQELRFDGDLYTPRWVRGHGNKREGWCGICKPGRWLVLKNSAFWYDKSFTHGISAATGQPFQEPQETRRMDGNPDVWEGLCGSCNEWVALVSSKKKGTTWFRHAYKCHTHPKIKDAPKRRRESSHSRALGASNMAKSKAHDSITSNPHQFSPMTPSVTPTPLYQRKALGSPIDGLGTMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3P9</accession>
    <name>A0A5N6K3P9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amine oxidase</fullName>
            <ecNumber evidence="4">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_002375</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="4"/>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3P9"/>
    <dbReference type="OrthoDB" id="5046242at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001613">
        <property type="entry name" value="Flavin_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF410">
        <property type="entry name" value="LYSINE-SPECIFIC HISTONE DEMETHYLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00757">
        <property type="entry name" value="AMINEOXDASEF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="5">
        <location>
            <begin position="98"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601613-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8296970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="555" mass="62107" checksum="74AB301634DC8EE0" modified="2020-04-22" version="1">MDLILVYLQVQSWNEGILDTIIPLLIELVVVTKLRETGPLPQLSQPLKTSNFAILYLITAPLPIQNSKPLIWTTGLESPDNYGNGVKKAHVIIVGAGISGLRTASVLQRHGVGVTILEGRPDRIGGRIQTSRHPKNGKARDIGAAWMHETSQNKLVQLIKKLDIEYYYDDGTPLYFTKEGRAGSQFKAKKVADEFADYCEHYFETHPHAPDRSVKEFMNEFVENHPLITNSERKWAPQAIREVELWIGTSIEEASSKYLSYFVTERNLYMKGGYDKIVNWAAKPLLKDPETIKMGEVVKNIQWGEGDNSVVVETLKGDKTSTFKADAVVVTVPLGCLRKKMINFEPALPEDIQEGIDAFSYGALGKVFVEFDEVFWPKDNDQFIYYPSPLPEGTPVDESSILSYATVTSNCFIMSGSKELCIQIAEPLTQRIEAMTSTQEIYNFFEPLFKLMRTEPYKDLPDFLNLETTHWTQDALAGFGSYSVEKTGDESELLIEALENHNRSRLQFAGEHCTVVGNGCVHGAFETGEVAARNLLEALGVQYDGNDTTARSVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K402</accession>
    <name>A0A5N6K402_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_002417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K402"/>
    <dbReference type="OrthoDB" id="5325022at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8297019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="76" mass="8153" checksum="54C6FEB2FF1DEE9B" modified="2020-04-22" version="1">MFATAALGGVEFILFVITLVILSIRLHCHRKAGGHCVPGGGAPKHNDIETKPQRNTATTAEQAQPEVYHPPVSHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K409</accession>
    <name>A0A5N6K409_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8297080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K409"/>
    <dbReference type="OrthoDB" id="5417887at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="115" mass="13531" checksum="641617AB4EA86762" modified="2020-04-22" version="1">MQRVDVDRMHLTQDENGKIVCRRRDEEQGFEYEDSRAMVARRLEEEEMSLTRDQKETVMSSEYHAGGLEEIPEYHTSGRLEEIPEYNANGSLQEIPEYHTIGDKENIPMTRFHAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5M5</accession>
    <name>A0A5N6K5M5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Sulfatase-modifying factor enzyme domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_001682</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; ergothioneine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5M5"/>
    <dbReference type="OrthoDB" id="659at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="entry name" value="paralog of FGE (formylglycine-generating enzyme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051128">
        <property type="entry name" value="EgtD_Methyltrsf_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017805">
        <property type="entry name" value="SAM_MeTrfase_EasF-type_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03439">
        <property type="entry name" value="methyl_EasF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397:SF1">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine-specific methyltransferase SAM-dependent" evidence="8">
        <location>
            <begin position="52"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="DinB-like" evidence="9">
        <location>
            <begin position="411"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase-modifying factor enzyme-like" evidence="7">
        <location>
            <begin position="588"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="578"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="642"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8297895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="879" mass="98388" checksum="BA5617C60A7B3190" modified="2020-04-22" version="1">MATPHISNGAVEDILRAPSHVTKITGVKSKSRQNSTHHIIDIRHDGAEIELKDEILASLRPQSGLKSLPTLLLYDERGLQIYEEITYLPEYYLTNAEIDVLERSAENIAASIPSNSMVVELGSGNLRKVSILLRALDAAGKNVDYYALDLSLRELERTLEQVPEFKHVKCHGLHGTYDDGLAWLKLLENSSRPKCVLSMGSSIGLSSEPMLPAINLPCAGNFQRHDASSFLKSFAEVLSPSDMFLIAIDATSNPEKIYHAYNDEKGVTHRFILNGLVQANRILGENVFDVKDWTVIGEYVYGTEGGRHQAFYSPNRDIVVRDVLIKAGERVKIEVSLKYSPEETANLLKAAGMREAQKWSASSDEYNIHLLTKSTMAFDTNPKVYASSTAPTLEDWKGLWSVWDTVTRKMIPDEELVEKPINLRNACIFYLGHIPTFLDLQLNKVTKEALCEPSSYLAIFERGIDPDVDNPEQCHAHSEIPEEWPPLEEILSYQEKVREKVQRLYASQNIPRSLGRALWVGFEHEAMHLETLLYMLLQSDKTIPPTTASPNFKEEARLAKLSRVPNEWFTIPEQEITIGLDDPEDNSGPDSHFGWDNEKPSRKVVVQSFQAKGRPITNEEYARYLEQTHEAKIPASWAQHQKANGYTNGNSNGHSNGITNGLDSAPLTKGYLEDKAVRTVYGLVPLEYALDWPVFASYDELSSCATWMGGRIPTVEEVRSIYSHADGLNVKKAERHLGKTVPAVNGHLINEGVEETPPSQTFQNGAGSQELFTDLEGANVAFKNWHPISVTARGNRLAGQADMGGVWEWTSSPLSAHEGFEPMALYPAYTADFFDGKHNIVLGGSWATHPRIAGRKTFVNWYQRNYPYTWAGARLVRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5M8</accession>
    <name>A0A5N6K5M8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HTH APSES-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_001673</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5M8"/>
    <dbReference type="OrthoDB" id="5346159at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990862">
        <property type="term" value="C:nuclear membrane complex Bqt3-Bqt4"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048315">
        <property type="term" value="P:conidium formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070197">
        <property type="term" value="P:meiotic attachment of telomere to nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044820">
        <property type="term" value="P:mitotic telomere tethering at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.260.10:FF:000002">
        <property type="entry name" value="APSES transcription factor, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037548">
        <property type="entry name" value="Bqt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006970">
        <property type="entry name" value="PT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38044">
        <property type="entry name" value="BOUQUET FORMATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38044:SF1">
        <property type="entry name" value="BOUQUET FORMATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04886">
        <property type="entry name" value="PT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0183">Conidiation</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0749">Sporulation</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="HTH APSES-type" evidence="7">
        <location>
            <begin position="61"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="195"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="269"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="408"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="283"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="330"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="419"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8297884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="474" mass="52197" checksum="326415E2AF230D00" modified="2020-04-22" version="1">MPTSRHLPAKVNPLMTEEIPPYETLVARRRLGQTDLAVKTGQLNTSSSTRAKNLGTFDYAHLRAPLPKGIHSGIFKPSPPSYFLMRRSNDGFISATGMFKATFPYSETAEEEMERRYIKSLSTTSVDETAGNVWIPPHHALELAEEYQILPWIKALLDNAPIEVNPTKDQTPKSILPPPKFDFKDFAPIPAPKLQLDEAPQIPPPETVPATSARVGRPRRSASPSKYATSSPRKIARARKTSARLASLEPVAAATNNVLEKVQENGVLETEKKVESTESTESDPTKEPVKEPTEELTKEPSEEPIKEPAEEPTKEPTEEPTKEPAKEPVEEPIEEESSEDASEPAVKVKVDTNVEVNGDVETTHTHVQVEMPAGFPDLPLPEDTEAMIAKAKEMVEAAVKQDAAIPTRPKQVKRKAEEFEADLEEEEEESLEAPAKKVKVAADLKKERVKTRALIGLSATLAIGAMIPYVFGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5N0</accession>
    <name>A0A5N6K5N0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_001670</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5N0"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF3">
        <property type="entry name" value="GPN-LOOP GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="186"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="186"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8297879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="226" mass="25973" checksum="D7F2053DAA8BAB63" modified="2020-04-22" version="1">MLTFAQLVVLHLSDSYCLTLPSLYISNLILSLRAMLQMDLPHLNVLTKMDKLASYPPLPFNLDFYTEVQDLSHLLPSLREESSVMQGSKFEGLNKAITQLVEDFGLVAFETLAVEDKRSMMHLLQVIDRAGGYAFGGAEGANDTVWQVAMREGTTTMDIKDIQERWIDRKEEYDEEYRRMDRMQFEELSKMQEEEENSRAAEEDDDLEEMARAPFDSGVKVVRTNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5S4</accession>
    <name>A0A5N6K5S4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001673</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5S4"/>
    <dbReference type="OrthoDB" id="5346159at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8297886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="75" mass="8754" checksum="C0C7D56A855A48D6" modified="2020-04-22" version="1">MCHQGSHNTDTKASSYTYSHSPLLPSIHAQYLHQEGPRWVLIVLSVLYNYRLYDILTECSSFLDLFNLNFYLITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5S5</accession>
    <name>A0A5N6K5S5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_001658</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the histone H4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5S5"/>
    <dbReference type="OrthoDB" id="3919494at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000012">
        <property type="entry name" value="Histone H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02969">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="12">
        <location>
            <begin position="50"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8297862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="123" mass="13536" checksum="086CE912A0475887" modified="2020-04-22" version="1">MAGKTVVSSSYAGGGGKGKGPGARGIGGGPRLRRHRKVLKDNINGITKGDIRRLARRGGVKRISALIYHDVREAIKARLYEVLRDCCTIVEHGKRKTVTVNDVIWALRRQGRPIYGFDNINDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5T0</accession>
    <name>A0A5N6K5T0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_001728</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the xlnR/xlr1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5T0"/>
    <dbReference type="OrthoDB" id="5365785at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000004">
        <property type="entry name" value="Xylanolytic transcriptional activator XlnR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051439">
        <property type="entry name" value="XlnR/Xlr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47663">
        <property type="entry name" value="XYLANOLYTIC TRANSCRIPTIONAL ACTIVATOR XLNR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47663:SF1">
        <property type="entry name" value="XYLANOLYTIC TRANSCRIPTIONAL ACTIVATOR XLNR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="10">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="59"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="142"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="486"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="665"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="486"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="500"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="676"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8297948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="887" mass="97331" checksum="F620A95199B2629D" modified="2020-04-22" version="1">MLSNPLHRFSGYNTMPSNNMISTGHLPSNHMHTTGLDTLAHGSQYAISQLHQQQVDLRQSSQAHRNGISKHRQHPYAMGMPGSNATSARGTGNSGPIRRRISRACDQCNQLRTKCDGQSPCAHCVEFGLGCEYIRERKKRGKASRKDLAQQAAAAAAANGQKSPTDQSPEERSPVESRNEPSSATSITNENVEFPRHTPSRSLSLNTAGIEKPSARELMKGRIRAGSLESLTEVPSQVHQPHVSRAEVDQTGSPGSLNLHGYSNMHGYRSTLNPHMMSGSGSHANFNTSQTGYSDLPYAIQGQSPPNYPGNTPELQCTPTISRATALGASPWQYHPNTFSLQCTPALLASILWVVAQTSDSAFLTASPSSRGRICQKLLELTVGLLKPLIHGTTGGSDNPSNFPNTIINGVALGGLGVAMPGSVSTDALNETGAFGAVGTLDDVITYIHLATVVSASEYKGASLRWWNAAWSLARELKLGRELPQTSASMASEQPNEGANDVDADGEDDDELPRSPGPITEEEREERRRIWWLCYIVDRHLALCYNRPLFLLDIECEGLLQPMDDTLWQAGEFYTGDSSIHITSPSGTQRTRRRGPNFECTGHSIFGYFLPLMTILGEIVDLYHAKNHPRFGIGFRSAREWDDHANEIARQLDAYGQSLRNFETEQIPPLPDDQNDQNMEGDQSSVNKPLEHNDIGTPSVHSVHSVHTASSHVSEANIQTQIVVAYGTHVMHVLHILLTGKWDPISLLDDNDLWISSQSFIDATGHAVSAAEAINHILEYDPGLEFMPFFFGVYLLQGSFLLLLIADKLQVEASPSVVKACETIVRAHEACVATLNTEYQRNFRKVMRSALAQVRGRIPEDFNEQQLKRREVLSLYRWTGDGTGLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5T2</accession>
    <name>A0A5N6K5T2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5T2"/>
    <dbReference type="OrthoDB" id="5397682at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="103" mass="11157" checksum="AE89759E05F885C0" modified="2020-04-22" version="1">MIGWDGEEAINNAELQLKAREYSRAFRNEIGGCVVGVAEKERVLMLAGDLFCSGHEPLELLEPPVSSPPKATSVLESKETTKKDKKVDGVVNTVEKPVAESST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5T5</accession>
    <name>A0A5N6K5T5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">V-ATPase proteolipid subunit C-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_001666</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10 11">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5T5"/>
    <dbReference type="OrthoDB" id="10264021at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18177">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18178">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000002">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="47"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="131"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8297872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="221" mass="23237" checksum="4A3DA03DED0A49D4" modified="2020-04-22" version="1">MSLTYGIGGATTALAVVGAYMLFTGDGEAFNVGQFLEEISPYAWADMGIGMCIGLSVVGAAWGILITGSSILGGGVKAPRIRTKNLISIIFCEVVAIYGVIMSIVFSSKLGLMESENLYSASNYYTGYALFWSGITVGMCNLICGVSVGINGSGAALADAADPSLFVKILVIEIFSSVLGLFGLIIGLLVSSKAPDFDDCCVLCISSKWKPMERRSGRNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K630</accession>
    <name>A0A5N6K630_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_001819</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K630"/>
    <dbReference type="OrthoDB" id="18431at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046455">
        <property type="entry name" value="Sec7/BIG1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20252">
        <property type="entry name" value="BIG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mon2/Sec7/BIG1-like HDS" evidence="2">
        <location>
            <begin position="44"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Sec7/BIG1-like C-terminal" evidence="3">
        <location>
            <begin position="473"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="662"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="663"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8298048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="692" mass="78879" checksum="2046A15B0FC0C176" modified="2020-04-22" version="1">MTRVRFEWANIWAVLGEHFNRVGCHNNTAVVFFALDSLRQLSMRFMEIEELPGFKFQKDFLKPFEHVMSNSNVVSVKDMALRCLIQMIQARGENIRSGWRTMFGVFTVAAREPYESIVNLAFENVNQVYKTRFGVVISQGAFADLIVCLTEFSKNMKFQKKGLQAMEALKSIIPKMLKTPECPLSHKSNANSDGSVKTPDTATTPVSRTTQEEAFWFPVLFAFHDVLMTGEDLEVRSNALNYLFESLIRYGGDFPSDFWDILWRQLLYPIFMVLKSKSEMSNVVNHEELSVWLSTTMIQALRNMITLFTHYFESLEYMLDRFLDLLALCICQENDTIARIGSNCLQQLILQNVTKFKPQHWSKIVGAFVELFERTTAYQLFSAATSSAAGGTMDSSVSPPLEDLGDDQSLKINGANGAATSDAESIAEQESQAPAARTPDLEDYKPQSGLQQQPVVVTAARRRFFNKIITRCVLQLLMIETVNELFSNDTVYAQIPSPELLRLMALLKKSFLFAKKFNENKELRMRLWREGFMKQPPNLLKQESGSAATYVSILLRMYHDEGEERKRNRADTEQALVPLCADIIRGFTQLEEESQQRNIIAWRPVVVDVLEGYMNFPREGFEKYIEVFYPLAVDLLSRDMGVEIRLALQGLLRRVGEVKLGLPPSARPATPTSPTSYQFGGGRRMSRRDSKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K637</accession>
    <name>A0A5N6K637_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">EYC80_001749</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K637"/>
    <dbReference type="OrthoDB" id="2414104at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="BIOTIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976:SF2">
        <property type="entry name" value="BIOTIN SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAB8297972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="228" mass="25250" checksum="5879B9C6D3319CF4" modified="2020-04-22" version="1">MISVESVLSAARIAKDNGSTRFCMGAAWRDMRGRKTNLKNVKTMVSEIRAMGMEVCVTLGMIDAEQAQELKEAGLTAYNHNVDTSRDFYPKVITTRSYDERLNTIKNVRDAGINVCTGGILGLGENKSDHIGLLETVATLPSHPESFPVNMLVAIKGTPLEGNKKVEFENMLRMVATARIVMPKTIVRLAAGRGELSEEQQVFVFHGWCQCCFYRRENVNYACCGMGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K643</accession>
    <name>A0A5N6K643_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_001822</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K643"/>
    <dbReference type="OrthoDB" id="166134at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15761">
        <property type="entry name" value="FYVE1_Vac1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15737">
        <property type="entry name" value="FYVE2_Vac1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.20">
        <property type="entry name" value="Rabenosyn, Rab binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021565">
        <property type="entry name" value="Rbsn_Rab-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036531">
        <property type="entry name" value="Rbsn_Rab-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11464">
        <property type="entry name" value="Rbsn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140125">
        <property type="entry name" value="Rabenosyn-5 Rab-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="175"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="313"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="550"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8298051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="635" mass="71178" checksum="F21BEF1E3F5D4503" modified="2020-04-22" version="1">MSSRKLGGGRILGSGKSLAPPTPHTHQRNSSFITTSESTLSLGSSHSTSPITTSTLPNDIQDLSSRVSLENGRSTSATAASSKLLCPICSEEMMTLLQLNRYAKKFQPLAVINQKLKGLDVFESNDVPISSNPIPNVLSGNRISTPELSRPDPDEVITRTHWQKSGFNDICTEPICGKRLGAVNGSVNCRKCGRLFCEDHTMYQIKLSRSAQHEPVRGLWCRVCETCFKSREGYNDHNGYTRDHTNDFMAMRRKHVDRAYLEISRLEKRLTKLTQLLANPPEDLAGNGSLLSLAGQKNSRKVLEQSVVTWEEDAKVPKCPFCQQEFGSWSFRRHHCRLCGRVVCSDPRTGCSVEIGLNVAAITDVQSEKHSENVSLDIRMCRDCKTTVFSKKDFQAELMEKTPSQRAYENLLQFEKGIRLLLPNFQRLLVALQDPEKPPSHAQLAEAAKVRKRLIDSFGKYDQAGRRIRDLPTTSATQQKIQKAIYQQSSSFLHLHMLPLKSLPKVLKHATPSSSHSSLLPQNGRSALSNIKYNDTTTETSSQVSDFSQISQMEQEEKELREKLIVLEEQKFFVQEMVADAGKRRKFDEVEALRTNLSDMQREIDSVNGMIQQLDFEGVYKREMDGGGGALGLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K644</accession>
    <name>A0A5N6K644_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_001577</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K644"/>
    <dbReference type="OrthoDB" id="3257095at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF1">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8297777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="203" mass="22554" checksum="80D31BCC351BA31E" modified="2020-04-22" version="1">MPWGAFRLRKLGVPITIIAMIYTVIALFFSSWSAFSTVDAANMNWSCLIFGGAIIFSMIFWLLHGRKVYKDRSTSTLPCNRHNSPVDLGSSNIAVIACLQVSIEPHLWRDSIRDASRDSTDLLEHSEATSSSFGSSGGDIEIERKYRSRCSGVPVEEVLRRVAKLSVTTIDSENEALALLEIERLALAETWGTMTQEFGIGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K655</accession>
    <name>A0A5N6K655_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_001832</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K655"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF9">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8298065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="45700" checksum="7ABB12E4AEF0DDA0" modified="2020-04-22" version="1">MDFTGEENFPWYPETTGKPLNPGHSTSGEIPDISSPEFAISNTQDKGVVAYAIQLSEVWFKITRYAKRRGSPSTLPPWSPQSDYALIMAQQMDFETRTSQIHRFKSAKFSQRSTEDLHANRDYWGPWLFIQFLYHTNLCLLNNPLLLSLRLKNIKSAIPEIFLQHISDLISSHASWVIRYIDMLEVRSFKVSDPFLAHCVAIIATIYLQEYFAEDPIVRQEKRDNFDKCLRFIRDFKEWPHVARMAEKLQRLRDTVSSTYKNPDAPPQTPNRSLLIDLGQFWEILEYSSSSEIPTSARRLFGPSLYSASIPTTHEISHASSLPEPTRVDRQDFEGSGPSSVKTSVVNMGEGGMTGQEQEAVHPPFHYSDDELAVLAESFFHQRGEGLGNLEDWWNAGNMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7Q0</accession>
    <name>A0A5N6K7Q0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Clathrin/coatomer adaptor adaptin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7Q0"/>
    <dbReference type="OrthoDB" id="1074925at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000046">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017106">
        <property type="entry name" value="Coatomer_gsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10261">
        <property type="entry name" value="COATOMER SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10261:SF0">
        <property type="entry name" value="COATOMER SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="1">
        <location>
            <begin position="21"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="304" mass="33709" checksum="3DA030EE9394D41E" modified="2020-04-22" version="1">MSYSKKDEDGDTAIMRVDRTSVFQEARLFNSSPIQPRRCRVLLTKIALLLYTGEKFPTNEATTLFFGISKLFQNKDASLRQVVHLIIKELAHSAEDIIMVTSTIMKDTGGGTDAIYRPNAIRALCRIIDASTVQSIERVMKTAIVDKNPSVSSAALISSYHLLPIARDVVRRWQSETQEAATATKSSGGFSLGFSTSSSQTPVNNSTMTQYHAIGLLYQMRMHDRMALVKMVQQFGAAGAVKSPAATVMLVRLAAQLAEEDQQLRRPMMQLLDGWLRHKSEMVNFEAAKAICDMRDVTDAEGCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7Q4</accession>
    <name>A0A5N6K7Q4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7Q4"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="134" mass="16233" checksum="78ED7037DA219349" modified="2020-04-22" version="1">MTEFHRGFTQKLKQQFHAIARMKKIQTICFKRVYSKSVKRGSIFRSMGLIGTRQRREKNRGREVGRERERERRRVRLRMDGGMLGKDFEGESNKVGRQRRKDNKNEIRQEMLVYNYNRKSKSKNPHHSFLYLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7V2</accession>
    <name>A0A5N6K7V2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7V2"/>
    <dbReference type="OrthoDB" id="3540796at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="717" mass="79386" checksum="0DF5E6ACA110EB30" modified="2020-04-22" version="1">MGTNQSQAPSDVGNKSSGNVKNRNQPSNSAHLGYSQQVRPAATGIRHRNFMKNEKGSTVPKGSSVTNPKRLEDPREPQASQAHVYNHIQPSNPPAQPNQYLNLESQALRIDNQNQNNPSSPASYQSQDPWWNSLAANYNIKKISQPRSRFVSHSDTNTQNERLMSSEPTVSEVTTSSPGQAGNQEVLPGIRRMASQASESSRPTSSQAVNPKAYLQTPETQHTDKRPVQSPNTQGKRARGYSSDRYSAQLSPIQPSYITSQSTPPPSVVRISSQHDQISNQTSNQPSNGTAPSPRTGFYQPPSQLSNVSSTSKGQYINDTSGQPPDTQSLNFHHRYYSHPRIQLNAIQNSQSQNQSTNKPTQISPILALSPQNQHNDPHAIQQGSLAQVPHNPEYNELGDQAASQYQHMKGARPPTDAEKPTQLTQQYNGQQTLDRTHYQLHDPRSQISMNSYNSYPRQLPTTINQALNTSPLQSSSIQPHITRSSPAPTLSTILNHSLPPTPPTPVDIPTPRLESILQNQPGAHPIAGSTTRQQGSAIDATPKPDTISQYPPMAHPLAGSPTHPHMPAVTHTPKLNAIYPYSPITHPLATPQPTPTTPQAVGPKLDFYLQRSTSTIDTTISFSYQYMEALSLSNLFSFFSQRSGVSLEKLDELTFRCMFGEYQQFVIGKNMGDGEWKRARKRIWRNWDREIRAVKQNGGDDDEEFWEVNILIGRCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7V4</accession>
    <name>A0A5N6K7V4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_000967</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7V4"/>
    <dbReference type="OrthoDB" id="2537459at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861:SF9">
        <property type="entry name" value="CELL WALL INTEGRITY AND STRESS RESPONSE COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861">
        <property type="entry name" value="GLYCOPROTEIN 38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="27"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8298794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="362" mass="38466" checksum="2E0EA088FCE50E44" modified="2020-04-22" version="1">MFHALRDYYRLGVATTCVFALVEHVNGVSMEYCSSLNTASGSANSSIYQSDGLCHDTCVDDYAFAIVQGQDCWCSDYVPGITTSTSDCNNPCPGYPDDTCGGDDTYGYIALTKSPSGTKGATSASSTQTSTSTSSSSAKKTTSTSSSVAPTTSSTTQTTVAAQRSTTSSSTSSTWTPTPIVSLETITGQVRTVTVTPTAPPSEPNKSSVSKSSGGLTTGGAVGLTIGLVALIAIIAGIIFFCIRKRRQEKAEEYNAVNSRRESLAGVGGPIPSRTMSENSRYVLGTDGRRVVETWEPEIHTPGSRKSQLMPVDPRLDPFASVYQRGDNKSRESINTIRDDHDYSRRVHQQGPILRAVNPDPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7W5</accession>
    <name>A0A5N6K7W5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mucin-7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7W5"/>
    <dbReference type="OrthoDB" id="3600083at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="354"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="506"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="625"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="660"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="682"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="747" mass="77967" checksum="4765D4E9C62610E1" modified="2020-04-22" version="1">MFEQNNKETSVSPPERGRSPGDNILFSPGSSTTPPRPLSKVRTSFVTVERGAQQAGQAIQLGLKRQDSNSEPNMAASSSMAKRRTSFSLDEQSHPKETAERKESISHEFEARKASIMVDELIPESALAETPAFEVSKQLGDPEPIKGPIPERGRELAKPAEIKENPKKSEDESKTPDASSPTVGTSKSPTSKANSSARASPTNSAPKVTTTAKNSDKAARTKSATRPAPISTTKLASAPKPSPRTTSPTKSSRPAPKTPTTPTGSLGDGKSLKSKTPERKPAIPARTPEKKPAKKTSNNSLAPSSGVRASSKPRSASRPAAKTRNPPSPPQSGSIKPKPRSPTRPVQLPASLLAPTASSGSKGATSTPPTRQTHSRASGAIKSEGAPRSQSRAGTSNTSKPNPPKTSHPPVSRSAAPLKKGTTRPSLGPASTLQKKSSTGNLPPASASLADDGFLSRMMRPTASSASKTSEKSPPPRRSLSTKRPSSSLGHSKVHDTKTASHAVQKATRPTATKAAASKSAPSAAKAGAKTVPKKKSEELPKQATKEQPKEQPKEVKEAPKEEATAAKVEVIPAVGDATTEHTEVTPEVEEAKSVDVSVEKEIEAPAVQTESPVVEEPSKETEVPEAVVPEVSAVETAPTSPAKEVDVPEVAASVEAAPVEAAPAEEAPVAPVAPVTEEPEVEKAPTSEEPKAEENVIRGVPSSEEPSKVDAAPSPVVEEDEDPEDAAARAEIARINAEMMAALKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K820</accession>
    <name>A0A5N6K820_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">EYC80_001093</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K820"/>
    <dbReference type="OrthoDB" id="29221at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012916">
        <property type="entry name" value="RED_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13948:SF3">
        <property type="entry name" value="FI21118P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13948">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07808">
        <property type="entry name" value="RED_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="110"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="14">
        <location>
            <begin position="209"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="273"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="537"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="G-patch" evidence="13">
        <location>
            <begin position="642"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="440"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="504"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="582"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="459"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="510"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="582"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAB8298942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="724" mass="80682" checksum="032DE05A8F920D4B" modified="2020-04-22" version="1">MMINNIRAKYQNRGAPGYDSYYSRKDNSRSPQRGPASGRPYDSEYSERPHRDERNQYDSRYDCGYDQVRSRSPRRENRSRYTDRDREGYRSPVRGRSPSPSRHHGEPPNRTIIFEGLPLEMTQEDISNELQNSLKVEGVEEIRLIKDKKTGISRGFAFAQFYTLPQAKRFLEECYPSVPFYGPSQASEPTKVRIAYSREKTDPERTSKHEDDWKCDVCYALNYSYRMMCFKCNGPRTRSTSHGVVVTQGNVSSYSGFATTGDSDASPDETASQFLLFRGLEPGVTEELLAKGVSKLYKTKANTTGDAHTAKKTKISSTSGDASLGAREGSLRRVLLIRDRKTNDSWRYGFAEFGSVEDAQNALAKYNAMEKFTISSKPVMVSYIHAGVFVPVLDVLDEESARFTFSPLSNSAICLMYWDAAAYANEFSIVLPEVSTKKPDSERDRLATAAANEGLVSGKDGESRSKKRKIEKDSTASTKKVVAPHLQFWTNRHNEIHGLPAKEFEDNESDSTAPITASKSEPITDDIPTQSYADLDRKCCLLCSRQFKTVAEVNKHEKISQLHRGNTKNEELVSKALAKLKKVENDKSSSDASAYRDRAKERRQAFNQPKQPAAQHNKLKATGSMASPSSQKEEENEPAVPAQSKGAALLGKMGWNAGEGLGAQGTGRTEAIATELYTQGVGLGAEGGKLGDAMKEAERQTKGDYKAFVGRTKEKAKERYETLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K822</accession>
    <name>A0A5N6K822_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_001031</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K822"/>
    <dbReference type="OrthoDB" id="7042322at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43510">
        <property type="entry name" value="AMINOTRANSFERASE FUNCTION, HYPOTHETICAL (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43510:SF1">
        <property type="entry name" value="AMINOTRANSFERASE FUNCTION, HYPOTHETICAL (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="3">
        <location>
            <begin position="53"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8298873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="388" mass="42843" checksum="59D732DC83F4C428" modified="2020-04-22" version="1">MVKIEPFAVEQWMDKYENTPGVLNIAETCAASLSIDDLVKLSEDPNLPHPISTSTKLTYGHIRGSPALRERLASLYSARTASALSRESIILTRGAIDANFLLLYTLIGPGDHVVCVHPTYQQLYSVPQSLGAEVSLWKLRKGKKYIPDLEELKGLVKDNTKMIIINNPNNPTGVTIPRSVLQGLVEFAKENNIIILSDEVYRPLFHGISVADPEFPPSMLSMPYEKIIVTGSLSKAYSLAGIRVGWLACKDKSIIEAIAEARDYTTISVSQLDDQVASYALNQSVIHALLARNIKLAKTNVALLEAFVNEHDDNLSWVKPNGGTMAFIRVQKKGEPVDDVQFCVDVIEKAKVMFLPGSKCFGRAAEVRIIYQGISELTSEYVNKNIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K838</accession>
    <name>A0A5N6K838_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SWI-SNF chromatin-remodeling complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5151921at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="903"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1070"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1176"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1361"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1414"/>
            <end position="1469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1508"/>
            <end position="1595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1623"/>
            <end position="1719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1756"/>
            <end position="1895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="609"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="709"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="756"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="770"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="903"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="987"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1631"/>
            <end position="1649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1671"/>
            <end position="1687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1841"/>
            <end position="1856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1866"/>
            <end position="1883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1884"/>
            <end position="1895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1895" mass="204560" checksum="1350B3A4C24E3A15" modified="2020-04-22" version="1">MARPYIPPSDQNGSLMSPMSSGSNTPISYRANVNRQKTKKWAEAKKIDYGGDDWGDDDDYDPYDAYGNEPKLAPASVSKPTGLRQQAQGLTGARGISQDRVQKSYGNLPSASAGSALNRRNSFEADDESRHFSNSTIRQESVAPAASPPQSADPPMSPPTRFSQMGVGGIRHTRDPSGPPTLHISTQQVSPPGLRKPSMSANPAPPEAPYTHDSMSLPTRTDTNDSSILSAGSVNTLSDYETSKDFSPSAVPAPLIMRAPPAPQSATNEVPATKFPARKSSLSTVGIEAQRIHQRSQETLAKPLPTNSGHSPSPGSAARPTVTPDQETSTPPAEDKATSPQLPDFHRISGFGADFFSRSKPDDGAAPPTETLTEQPEPAIPGDFQPPGDTSLRSQPSFGFRSVVNQAFETTSDNSVPPTPASKTGSEVKRSDSESTGTTGISPIMSRGPSTATVADNRNREMSTPAIMELVEPSSPASQNVEQENADEMLPPTFIPGHRRDISTPSPGNSPARTPDLNDASKRVSMGEHAWISSASPADAAEYESDHADEESARPPLTREASFRPQLPGGWQSYTTTAATSTAQLESVRSSSPQPSDGPVQDMAAVDLTPTTAEHSLPSSSLEAARVTLGVKPDSIPTPDPDGNVHSAMTPHPELIPNPGNASPEIQSRPDVAVESIPTESPPHLPTNDGSASNDEAIPENPPHPTVDLPHHTGDSTSSDEHLLPPSQPEGIPTSSTDTGPLDEENEKLRREIVRSLSPLPLESGLSNDNLRERRDSNDADQPRESAYLTDVYDDYWNDTADDEHSPPMAPMEQTIPADMPEIRPLSSHRISKQQARPPLPERFSWERSMESIDQTDIATPELPASHVEAPVENVENVENADVSHGELQQLDPEPYVEKEVWKEPVQGDEHLERDAALGTGSAVLEGATAATTSQTSHHESPPTFNVSLAQEKDQPQSALSPITPAHDNEQPAYGSTLDLSIDPLGSNPHSPASNPSPFPAREVSPLRRGSANSLRTSNLGKILTFKEIVAMKDVHERVHAFDETRERFAAMDSGLHEWISALKAEQPEHHDVTGSYGGFRSSAPTGSTRRNTKSGLGGLQLPYHQQYLNASATSQSSAPASSGIQQGFSPAHAKITTQQVQAKGKEFLHSAGMFGGKAGKAGFQAGKGLLAKGKNRLRAAGSSDKTSPPPKPRNPNRSSWSLALNLSKATGRTDPSRHAEQNIPFESANRSRMSIPSGVLTSAGMVDVPTSHREAQAAHVEDVNVLSREDAGEILASDGTEEQHLVKSPEHTNGHFANAEQTNQYLIDTESAINQPSVLAGQARSTRSNSADAAFYDAPEEQPGPKESVPASLVTQAEIMQPSISLESPTRPPISMMNRPRGASLDQVAPPGQPSQSAIRSIQAPLSIQSTNQRNVGLEEQGRQPPLKTLPPIRRTSKFGFEFGSRRPQTRFPISDDEDEDGSNGSRQDVIISNNQASSSEDSASQQNLHTEVPIADIARDLKLNAQSGPQPRFSVFPRISDPFGHNNQAQDPWRSKPAVKHTRHDSWNGVSDKSRSRRGSTSDQYFPTRRDSNAAPPLIPSLPFESPPSSAQRYPELFGGAAVDIRDDHKMSGRYYQARQGPSDAFIPRQQTDEPQGASPPQDSQEPTGHRRRRSSDLVNRGMNFVRSISRERRGSVSRERKGSISREQSGSVSRDEPISPIDTFATPPSRDDRRNVRGSGFWGNFDITGQQPFNSPIGRESMVAHYSGSQSDFMASPYDSPRTPGSVLNPNPTLEAPRSKILGRSTTTMGKGLQKDDKKSRLGGLSGIFSRSPKGDGSVLFKPKRATTDLSSFGPRSGTLSSPQYQPQVQQEVNIDHKRRPSQPLNFFSKFNPSTSLQKNENPRQDKKDRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K882</accession>
    <name>A0A5N6K882_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K882"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8298924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="369" mass="42179" checksum="6279DE67E79E0406" modified="2020-04-22" version="1">MQKFGLTWENDVEDILTIKDTFQEFAKGQRPQSYRHRVAFKVKGYNPGQVRAAVERSLLKRPILRTILVGDPGATAVHAVLRPSHVVYDILIKQESFSHESEVQETLVDDFGERFEARMFKAIVADIGGKDTALIITLNHSVFDALFAYSWYSDLDMFIQKPDFVPAPTMPFKLFADIHQQYKNSSLALSDINFHIRRLRGISRFTEALWPLKRAPGWMIGNDEGSKDFIVRRKWPFLPGWIADRLPSAMSINGPTLTWTMNMIQIKPAETCGELLTRMGRDQEELSSRAHAPWYQVLNGLGDDEGPIAKEASMRQVFNWDVSLKHLDSSVNDYKTLSPMGRMDWPDCGFFWNCGYVEHGTLLLCRVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K884</accession>
    <name>A0A5N6K884_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_001108</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K884"/>
    <dbReference type="OrthoDB" id="421009at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15844">
        <property type="entry name" value="SNARE_syntaxin5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021538">
        <property type="entry name" value="Syntaxin-5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF3">
        <property type="entry name" value="SYNTAXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11416">
        <property type="entry name" value="Syntaxin-5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="215"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="122"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8298960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="307" mass="34481" checksum="0FF1FF4DB3798093" modified="2020-04-22" version="1">MAVASIQDRTNEFRSVLTQVQKRQASSKVGAQRQSLLSDSQKAAANGDANAHGRPRRSEFARKAAEIGRGITGTMEKLQKLAELAKRKTLFDDRPVEINELTFIIKQDLSSLNQQISGLQSLTRAQHPKADQEGRTQQKRRLHAPRQAHRRLLQLQRRARSPHQEHPGLALPHRKFSPLYSTPARGSPGPGQDLLSLNPVGDQQLLMMEEAQPQNEYIHQRGEAIEAIERTISELGGIFGQLATMVSEQSEMIQRIDANTEDVVDNVEGAQRELLKYWSSVSGNRWLIAKMFGVLMIFFLLWVLIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K888</accession>
    <name>A0A5N6K888_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_001141</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8299009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K888"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173">
        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173:SF74">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="91"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="195"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="262"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8299009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="323" mass="35156" checksum="78822071B8B84CF1" modified="2020-04-22" version="1">MVKFLIGRGELDENMKQGEDALIRAAIDGNFEIVKLLYEEGHVDLNARDANGATALCYVAKLKGMDNNAELGIEMAQFLLERGADPSLCGKDEGPLHGAAIYNHPEMLQLLLKYGADITRVVNGWSLLELAIKYNSPLAVTFILGYTVNPKDLDKHQGMLNAALLYAAGKGDRNAILELLKAGADIDTRQTKEAGGNTPLLVAIGNEEMQSARLLVRQGAKLDIVDEKGRMPLEMAIRKGYELLTRDIVEKGGDTNVKLGENGDTVLSLAVREGHLKVVEVLLKRSMDVVGENKFGETALDIAEENGDKRIIALLDGGEFEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K892</accession>
    <name>A0A5N6K892_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001086</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K892"/>
    <dbReference type="OrthoDB" id="2851338at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8298934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="124" mass="14509" checksum="41558A763188DC20" modified="2020-04-22" version="1">MRNHFKFSMRNTFIITNIRIPSTVPTTYYQLNMAPIPGLLYVTMQPQESLPDSQWHDWYNNEHGPLRLRLPFITNGFRYRATDISSSNPASPSHPEWMALYDVTDMAAMNTETYLRLRGPEEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K893</accession>
    <name>A0A5N6K893_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_001113</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K893"/>
    <dbReference type="OrthoDB" id="3594623at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="415"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="415"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="334"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="563"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="218"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="264"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8298970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="675" mass="74624" checksum="6431E95B5D4BF832" modified="2020-04-22" version="1">MELSNFTAKALEKVEKYSLILYATGYFTQEEWVKHDALLHKGKYVFTKGPQASLPIVMGPTIGLWKSNARPATREESRPKPQNETEESLINSDEDSGEKVEAALASINPIDVSTTNNTGENGQEGGSEATASLIKENIRSEDETTAPANLDEPVTVNQEQESAGSDGPVEYLPKDTLGNENSTKSPASASPAKPKLPLKVKVKKESTESLATPKARTSKTELSRAEEERRIKLFTKAFGRPPSAKSDYHQPTNPEFKPRWLGESSTDSTPSTRSTTNAHSKKPDASRNAMKKSGGFSMNDYERKCTAEWENDSEENGPSFRLDHSRFAVLADMHHQSSSRGTESDSTVSSQKNGQNRSVIRWQSSIDTMVDSKELQITEGHLNKSKNSPLHLKSTGPKLTTRERLRNKPLEIVVPKTEVCYFWAVGDRCRYPEALCRDLHEDREYTLQTNVRDGKPNPGPLCEVIDPIPAPPSDGSHAPAQDLASTVGKRFTCFFWHQGGCWKSERECYFLHTYVGSEGILHRKVQTQAHINTKRALIAKPKFEDTNEDSVDAEWGASEFSTNATSGAEPELLSPGHDNPVDEEEQATLEPGTLKWPENQPSPKCGNACSIRGTGKKLDAPDPAYAFRAVTLIWDTTPKSLTLALINTHNLDIQPRSLTTGNTARIIDNHHSTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K9Z6</accession>
    <name>A0A5N6K9Z6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_000226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8299985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K9Z6"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8299985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="75" mass="8829" checksum="248FA757E96D4784" modified="2020-04-22" version="1">MDEKGRCCASFSVEDVDKNFLGTRSERSYRDDFPLGVDDDDDADDADVLIKLSQVDTEMWMKMEMEMEMEMEMWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBF9</accession>
    <name>A0A5N6KBF9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8035 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBF9"/>
    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058348">
        <property type="entry name" value="DUF8035"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42081:SF2">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42081">
        <property type="entry name" value="ZINC FINGER PROTEIN DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26118">
        <property type="entry name" value="DUF8035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8035" evidence="2">
        <location>
            <begin position="431"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="515"/>
            <end position="533"/>
        </location>
    </feature>
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        <location>
            <begin position="536"/>
            <end position="590"/>
        </location>
    </feature>
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        <location>
            <begin position="605"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="641"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="709"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="722"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8300484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="772" mass="87841" checksum="0A7DF33CE2601133" modified="2020-04-22" version="1">MSFGASPSDVIIAVTFCRELYRKCRSAGGEYDEISREVRGLHNVLKHLKSEVEDEDSLLNRDQSIWGRQLAPIIGDCDITLKQLDDLLLKHERLFNENGGRNGSSEALWDKMRFGSNEMDQLGGIRVKLISHKTSLTLFLDTIQLHENENEGIAKNLNVQGEQLDIILDKVDHIAAKISQRARTPITNYEDDDKEVWKQFRRELISEGFSNDVLQQHKDVLRAYIRQMELDGLLGEEPSRSQMPSPVSSHTKRCVGSTHSESSRGKSPFFDVVDTGDDFNKAKEIIQQEDNMKFPPSMKNFTERKWEKDTSGSESSDTSSKHRRISSSNSSIIQTSELLPFSATPQLLPPSSPSSHHSYPDESIRPVALRPKQSSDQGSSPRTSGVRFDLPVRQTSSKISSPATGTSPRPDATMPLKRLAPDLYGNEISPDAKWTKVKRSLISPEVLNQDGRRYEARPEFVAILGILTKEEIQNYASRSHILREERWRRHHQASIGPEQISRRERTSRTRRRRNSSASESLSCGSDTTSGSDSDSNEVRRPNKRRDPDEMDRRRHDREYRRRYQGERGDRKEESERRERTERKERDREPSDTFSSNPVPYPPQPQLFSSSPQSGSSNIPRPWNIPGSNQLPQGYPSPPYPQQQGYTQQPPYPMQGQQYPQGPPYPATQQYLSPQPYLPHTNPNTHSPSSPTYFPPSSSPCNRPYSHDYHPHRRRHHHSHHSRDRDRDRDLAYPDSHKSRDGGSRWRDHLTAAGLGGAAVGLLNVLSEAADGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBG3</accession>
    <name>A0A5N6KBG3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBG3"/>
    <dbReference type="OrthoDB" id="2247093at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14705">
        <property type="entry name" value="bZIP_Zip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="579"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="620" mass="67106" checksum="E24633CAF2ED0FF2" modified="2020-04-22" version="1">MPAANKQPQLDASRGEKDPLHYDPGNKSMSSGGCWCGEGYSQCLTREWCANLQNLHLSEKSADPSPLAGKPHWQAGAIDIRSGCSSYQQSWEGEGKRQCPGPRDQEGLGDQDSMSQRLSASRPASRSPPESQKITLPPVQVRDDPRHGERQADRQLEQDNRGLQQPHHTLPSPSSRTPLSASTGEDWKSSGPSRDLGVHSILNPTEPESASNSNRRLSVGTTDSPLSTKAGPTSHFGASPSMTTTHPYSNRPPVSTSPSLESFNPNFPRGQPRRMLTPRSPRPASIGRAPVHGTINAQDSPFLPSRRPELGQTPVSENPPTPTPPGQIQQAQHYGFPSTGTTPVDRRTESSQMQASGRVQHSASPSISASSQTPSQTSPASGYPYHQSGQNQQTSGSYFPGSSFGSSVQQGGGLQLQAPPAASEGASARFRQRRKEKEKEASSNIEKLQSQTRELERRLRDAEGERDFYRGERDRFRDMLLRNPGTRDMALHGPPSPRSMRPMSYPGPPPPPSGPPMAFQGPDNGERASRRRRTDAQGDFMNVPYSHSPASTLPPVQSGFPPAHSQGLPNLPPLRIDNPSTASTTAVSTPPISAGPPPFDSYSRGPYDRAWPKQEGGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBL9</accession>
    <name>A0A5N6KBL9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_000717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBL9"/>
    <dbReference type="OrthoDB" id="3471506at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8300558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="107" mass="12516" checksum="76D63EABB5DA89B7" modified="2020-04-22" version="1">MVVGNFTPHIAKFARFSLGRFTNRWANEEELNKPAILKENKMPKDVPAQWNVLRWQYQSELLMEIKNRDMERARQQQVQGGMTLGMVEKAEKMSGFMGDNHLWMCAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDJ2</accession>
    <name>A0A5N6KDJ2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_003370</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="952271at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02674">
        <property type="entry name" value="Peptidase_C19R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF24">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00695">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DUSP" evidence="10">
        <location>
            <begin position="311"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="679"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="107"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="178"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="522"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="618"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="959"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1170"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1320"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1521"/>
            <end position="1672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="620"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="964"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1172"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1192"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1280"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1323"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1591"/>
            <end position="1604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1621"/>
            <end position="1632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1654"/>
            <end position="1669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8301520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1727" mass="191535" checksum="48EACEAB8EEDD402" modified="2020-04-22" version="1">MRSGSYGDSRHCDDDEDDEEFTPKSPLSNETKALELIAKKNDSKEQSGRSGRSGRPDKKRNNNININIYIYININIDNYSNNNNNNNNNKRTTLLILYIVPGIETDRGPDIPISSVEGRESQSPTDLPLFNTSLQESHRAESLPPNTIPSHLQTSSTLPTGDYISSAASSPSAAYAGLSIDSDKGGEFPSNKNRRQFPSEQPFELEQQGKSPRHRSIMGGAEDMPQRSSSPLKRPASELEPDLPLSSQKEDVDMVMVPNAQEDPESTIAAPTAIRAASVNMMRDEVAGDDSAESAPAAENGPVPDPSTDIPSIDFQVSTVTTLCRTEGEKQLKEGNSTYLVSKKWLERVTSRTSEAKAKSKETLSDQDIGPIDNSNIIQRIIPQPGREDFVQLKHGIGEDFFELFPVDAWNMVFDWYGLKENEKPILRFAHNTNPDKTPDAIPNVTYEYHPPVFQIHRVWSELGNKVDASTKSANPDAPIIVASRSMRMHDFLKIIKEAAGVPLKQKIRLWRVPRTLPAAEPALSTTVGNATPPSSRPGTPPTANTDVTSSEVQDSWKKLLLDVTEFTKVERDSGRIKVEFEDSTVNDNYNGRSDLDFCGLGDDQALVIDELVEGKDGYVSNTKPSQNGKLNGTGRKGNSSFIVSSQNNSGRNSPAPSSGYNLRSSNRRSKNGRPPGTVGLSNLGNTCYMNSALQCVRSVEELTKYFLSDSYDPELNRDNPLGHGGAVAESYANLLKEIYKEPAPVSVQPRYFKNIVGRYATQFSGYGQQDSQEFIGFLLDGLQEDLSRVKKKPYIEKPDSTDEMIGNPDAIREMATKVWDITKQRDDSVIADLFTGMYKSTLVCPECDKVSITFDPFNNMTLQLPIANLWNHSATFFPLNDKPIIVMIEMDKHASIRTLKTQISQKVGVPLERLFACEVWSKKFFRWHFDQETASDVIQPNDLLHVYELEAVPTNLPSPAKSKGNTFGGNNSDEPEHVHWDSSAAEKLLVPVFYRRRTREKWSSKKGSWELTTVPHFVVLTPQEARSEEAIKRKILEKVVTFTTSSIITDEDDPSSASESIDPDLVVTTGSDADSSGDSKFVAQSLDGEDEIVDVAMKDSNTVRKSVENRPTAPLKIFNTSRPKWVDPAEFLSGELQNLFEISYFTDKQGRLPLHWDDKLGDPTFKKISERNPQVQQMNSDDTSCGFDLVDGSAGSVSSKSSRDSSDDINSFELPPTRMNEESSDDDLNPTSPPKALPVRPAAPKSGGKALGKNKRRSRHQATYTKKGKAAPLKRQEIEADDEQEAPDDGPLVRPGEGLVVDWNEDAWDNLFGGSIDKNNGHGCSTYQNPPTLRDPDLLSTRKTRDSKKHTGIPLDDCLDEFGKEEILSEMDTWYCPRCKEHRRASKKFEIWRTPDILIMHLKRFSSTGYRRDKVDALVKFPIEGLDLSSRVVEKQDGKEEIYDLIAIDDHWGGLGGGHYTAFAKNFVDGRWWSYNDASVDLVKNPSSMITASAYLLFYRRRSSEPLGGTVMQEIVRTFDNTLSSDEEESGEGRRLGGNSSQPGSPSALTGVGAAHRQPDHPGSEDGVVTMTANQPDLESAPPYSDHNQDMSMSGNDALNATQPIWGWDGLNQNPGTFPSGTGSEAGEAGSVADFSDGDSNGVLHGSEPSRASMERRKEEFESSRVDDEFQEEYIPDAVHDAPDAIQVMEYNRQRNYDLVSHVQQDEIEEPAAEIHLEEGEEVKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDJ7</accession>
    <name>A0A5N6KDJ7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDJ7"/>
    <dbReference type="OrthoDB" id="635774at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF706">
        <property type="entry name" value="PROTO-ONCOGENE SERINE_THREONINE-PROTEIN KINASE MOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="115"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8301467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="567" mass="63899" checksum="3F87B2614DD1861A" modified="2020-04-22" version="1">MHFRDKSKREKFFVTYAETPTRWRRVTISLDYRNAPSNSLEEELQKTRFQRDKSARIYEAIRESLPDIQFYDTVTNLKLETQDERLHVHVVEDLSEVIHYPPVKSLNHLPCRRVLEAELEFDSHLSGFVYKVIVAGQVFIKKEIPGPDQVDEFLYEINALHQLSGAHSVIQFGGVVLDNEAKHVKGLLISFAEQGALIDVIYDGDGGIPWARRERWAKQIVHGLSEIHEAGFVQGDFTLSNIVIDGDDNAKIIDINRRGCPVGWEPPEVAALIESNQRISMYIGVKSDLYQLGMVLYALATQQDEPETQRPLKLTAIPPQVPDYFLEICSRCLSDNPRYRSQAAALLNLFPEVNEDCGSYEDESPTPIVIDVRPADEGELLVTVHDNHMGRGSLSEAHDDIPERGRSRSKPHSPLFMASRSPEKTITNLRTNGIRPSQIPLPRSVSSSDYSKDQIDQQQSHNQNTSTIENSTLETRQQDSEFPSYSEKDATDIQSNSTTEHARNTVAAPNISMAYAEDFAHIGTGVDSAHRGSFPFAPVDIDDDDLTIDNEASNVLYWKAEEKISLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDK1</accession>
    <name>A0A5N6KDK1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_003378</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5186at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103:SF2">
        <property type="entry name" value="MIDASIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103">
        <property type="entry name" value="MIDASIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024900757" description="VWFA domain-containing protein" evidence="5">
        <location>
            <begin position="18"/>
            <end position="2021"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="6">
        <location>
            <begin position="1805"/>
            <end position="2009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1161"/>
            <end position="1677"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1164"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1196"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1214"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1271"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1313"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1341"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1352"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1406"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1435"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1446"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1494"/>
            <end position="1509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1555"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1581"/>
            <end position="1595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1638"/>
            <end position="1664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8301530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="2021" mass="225513" checksum="FA95DB6BA10DBB78" modified="2020-04-22" version="1">MQYSALAWVHFAVGCIALYVPDRAFDPDKRQRLERQRHEEVIQELQEKLDALQKFERLFSGQESNIRCQLLDAEIVEIGELPEASQQVYRPESSELHKLQGEFKNLLKVVLPSPSITSKIHQYLINDDQVVLNEIKLIQNNLLQIIRRLSERFREYSDLATPVINILRCLQIGLYMATLSSNDPSNNSKAALALSRATPFLGGTLKSIDNEIVSGQPLEYLKLMATTTSVEPIDSIDTQTRELLFTSIHSCYEQWTKKLESDRLEGETKAGLYRFRGSAEDEDEIDEEQFNELFPSYDEENPIAQSAAPQQQNVRDIAVTLARVHGDIFLGGELPSKSIMTLIKHISTHMGKLQGGEAGLGDQNTIKALLPGSLLLLSDKIDDLSSSATVPESYNFYTDANLPETRKLVSLIHQVQTRFRELQAVDEIAHMQPLEDVMVSCKELLKFRHTEPLAKIITKVEKVHGFMHEWQFGGWASRANSALPLYDNLTATIVNWRRLELSTWAKLFDMENKQCDDDARSWWFVAYQVIIAGPLSICESIEELRGYAQKLLQDLQAYFSTAIMGQYVQRLKLLKQLEKHVDLLVLDYPNLTIIASAVANFIALYSRYEKPVEESLKRGRVSLEKAMRDVLLLASWKDTNIVALRDSAKRSHHKLFKIVRKYRALLGQPMDSVIKQGLPDEVAASEAGTSYLAPAQFPTVDQSALALCASTVPSWTQKPKRFINVSNTVSMMIDKSQLTTSTLEGSSYLESFLENIVTSTSELQKATPSILTEDNKDTVKHLKSQKRKLFADTLKDLRQMGIKYNLGVNALAKQDSLSIVLANTDYIPSSGPQDLEYYFYKTVELAPRAREASRQHSDDLSGAEVARSTGFLEGLLQVLLVQRNILSNTMTSRNTFQDVIKMAKGLWAPEIYAIKNTTTISNHENILQWLPNILSVGLELVNTHAKLGRVDSKPVVESLSSWKDILIDLRVRWTSSSILPSGIISTQREELEMAVNDATEQLAVDLCTLIKQRPDLSFILDQILPWTTINSSSAAAVSVQASLEALDQKLSTVCNTILAAMEKYHKSINDLPTSTEDQGWLIKSDTVLASSIKALHCENVAEQIKQSFEILRHLNLVNDNISRGAGAIFAVALPIIQQYYNTLEESIARYATLHRSTCFCTPSEKQDAQDGKTEKLEGGTGLGDGEGAEDISKDIGEDEDLDELAQEPNKEERGEIEDEQDAVDMADGEMEGEMGEAEEKEDDEGSGDEDKDGEEMDEEAGDVDDLDPNAVDEKMWDGDNEQAEKDQEGDDSKGKASKDEQVAAQETNKEAGEGDEGEEGEEEEEEMAGAEQSEEVQQQDDVEKNDPHADEGEALDLPDDMQLDGEEKEGSDGSDDGMEDGMDDLPDMEDETKETDEVANDGKEEPDADNADGQEDQDIGDEMDIVDLDEEKDQEGEKTEEAGEKAEEEPEEEQQPEDQDGLLRDRDDEATADAENAVPSDVQGVGEDQDDNEADKNADSNSKAQRDDGGQGGDSSENKQSAAEDGEKGRQAAGDAPQDAQDDTQDCSSAQPFKKLGDALEKWHRQHSQIREPTEEKDQTQDQNIDMGTESNEFQHLQDEDAEADTQALGTATEEQAHALDESMAVDQESKDMPETFQPDEVEKDSADEDNVMDLEDDAPEPEEPSNAYEGRAGASVHQAKNDMDEEVDDNTHAQANEDMDSDVEEVDTQLDNTHLDPTMTVSVRSATEARAQWTHYESLTRPLSLSLTEQLRLILAPTLATKMRGDFRTGKRLNIKRIIPYIASSFKRDKIWMRRSIPSKRSYQIMLAVDDSKSMGESGSGSLAMETLVMISRSLAMLEVGEICVVGFGESVKVAHEFDVPFSSEAGPVIFENFGFEQSRTDITRLIRESITLFRTARQKASSSPADLWQISLIISDGVCSSSEHDNIRRLLREAEEERILMVFVIVDDVRTKKKGESVLDLKEAKFVKNEMTGRSEVKIERYLDTFPFRYYVVVGDVGELPGVLAGVLRQWFGEVVGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDK5</accession>
    <name>A0A5N6KDK5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CTP synthase (glutamine hydrolyzing)</fullName>
            <ecNumber evidence="3">6.3.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_003350</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>UTP + L-glutamine + ATP + H2O = CTP + L-glutamate + ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="3"/>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDK5"/>
    <dbReference type="OrthoDB" id="1739076at2759"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097268">
        <property type="term" value="C:cytoophidium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019856">
        <property type="term" value="P:pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="CTP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550:SF0">
        <property type="entry name" value="CTP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="10">
        <location>
            <begin position="24"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8301496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="254" mass="28232" checksum="3B41995088D00E59" modified="2020-04-22" version="1">MRCGKKLNLIWVEAEHLEDDAKPTEFHKAWHDVCTADGILVPGGFGDRGTEGMIAAAKWARTNKTPYLGICLGMQIAVIEFARNVCGITSANSVELDANASDKVIIYMPEIDKVNLGGTMRLGLRPTEFQPGSEWSRLRKLYGEKTEVHERHRHRYEVNPEYVDRLHSGGLEFVGKDDKGERMEIVEIKDHPWYVGVQFHPEYLSRVLAPSKSYLGFVAAAAGCLDKITEDCLNAELTNSVDGDLANGVNSVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDP1</accession>
    <name>A0A5N6KDP1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GPI-anchored cell wall organization protein Ecm33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_003017</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDP1"/>
    <dbReference type="OrthoDB" id="536881at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.20.20">
        <property type="entry name" value="Receptor L-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051648">
        <property type="entry name" value="CWI-Assembly_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036941">
        <property type="entry name" value="Rcpt_L-dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31018:SF3">
        <property type="entry name" value="RECEPTOR PROTEIN-TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31018">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12454">
        <property type="entry name" value="Ecm33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024796468" description="GPI-anchored cell wall organization protein Ecm33" evidence="6">
        <location>
            <begin position="19"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8301112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="40640" checksum="64DF99C05CC66845" modified="2020-04-22" version="1">MFSKVLLPALAVVGTAAAATNAVCSQATATINSAADATALADCKTIKGDVVVSTTAPGIISLDGPEEINGDLLIENNGAITSFSSSSLTTITGTFGLSNLTLLSTLQFAVLDKIGTINWAALPALPSLTFTNAVSSASSVTITNTFLSTLDGINLNTVDTLNINNNNRLKTFSTQVGNVTTLLNIDSNGKNLDVSFPNLIWAANMTFRNVSSVSIPSLAVVNGSLGFYENYFTSLNAPNLTAVGNTANGQGGLAFVANPSLANITIPNLEAVGGAFQIANNSALGGISFPKLTQVGGAIDFSGNFTTPELPKLNDVKGGFNMQSTTSIDCSGFKSEHDSGNIQGTYTCKTTANAQSGTSSSSSSSSSSSATASKGAAVSYGVNEAVMGVSVVGSFLSMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDQ2</accession>
    <name>A0A5N6KDQ2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CCAAT-binding factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDQ2"/>
    <dbReference type="OrthoDB" id="10263597at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016903">
        <property type="entry name" value="Nucleolar_cplx-assoc_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428:SF5">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8301527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="91" mass="10035" checksum="39A1ABE8675C4909" modified="2020-04-22" version="1">MTCSLQLPEKSATAMIALLGKVTKIHETKVKSLWNTEERKGDGMFDGCSTEVEGSNPMASTIWEGELLRLHYCPAVREGLKVVEKNVIGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDQ3</accession>
    <name>A0A5N6KDQ3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDQ3"/>
    <dbReference type="OrthoDB" id="635774at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="31916" checksum="6AEB5D8C5E4275E0" modified="2020-04-22" version="1">MYIGVKSDLYQLGMVLYALATQQDEPETQRPLKLTAIPPQVPDYFLEICSRCLSDNPRYRSQAAALLNLFPEVNEDCGSYEDESPTPIVIDVRPADEGELLVTVHDNHMGRGSLSEAHDDIPERGRSRSKPHSPLFMASRSPEKTITNLRTNGIRPSQIPLPRSVSSSDYSKDQIDQQQSHNQNTSTIENSTLETRQQDSEFPSYSEKDATDIQSNSTTEHARNTVAAPNISMAYAEDFAHIGTGVDSAHRGSFPFAPVDIDDDDLTIDNEASNVLYWKAEEKISLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDQ6</accession>
    <name>A0A5N6KDQ6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PKS/mFAS DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_003356</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDQ6"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050444">
        <property type="entry name" value="Polyketide_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45681:SF6">
        <property type="entry name" value="POLYKETIDE SYNTHASE 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45681">
        <property type="entry name" value="POLYKETIDE SYNTHASE 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS/mFAS DH" evidence="3">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="2">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8301505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="844" mass="93100" checksum="298B624FDDB5026A" modified="2020-04-22" version="1">MSKIGITYGPMFLGLQDISAHPVDHLAVAKVENLVNPKDSPYQLHPTTTDCALQLFGPAASRGQPHSFVKLLLPQYFGEIYTKRPRPNLKLELSSSVSVTGWGAIHGDAFAIAGSEVVLKLLYVHLVPAADNSAADIDPVQAIESSKRLVGAPSSTMAHLEKYRKWLAGHVQQANTAGYEAVDDASHIFTLSSAARLQLIEETAKQMENYNSAPVGRAIIRTFENSVDIFTGKADALDLLMQDEILRKIGDLVAKFWDFGDFLGILSHTKPDLKILEIGAGTRASTSLILDSLVSPSGERAFHSYTYTNISAGFFVQAKERFKNVPRMKYSTLDVSKDPAKQGFELGVCDLVIATNVLHATPYIGETLVNVRKLLQPEGRLMLQEICSSEPTQQRGDGESMLTFLGTKWFNFIVELTQAGFNGLDAVVYDEKVPYYTNATMIASPHNIPKANNKRIPVLSTAPTCSAAARLSNSIAKHGFEIEFCSLTDTPKPNQDVISILDLEGKAFLENVPETEFNLLKAFIASLKSSGMLWMTKSAQVEALEDGGTFERALEAFEKFQARCKDLEVEPDFEYAISRGVIHVPRFQWVSISDELFSRKEFDALKTLEIGKRGALKTLQRVERPESKLTGDEIYIEMRAAGVNFKSVLITMGIVDNYIGDGNGLGRIFNSRNSSFLPEIMREANGYGLDVVLNSLSGDLLHASWKCLAEFGKMLENGKRDFIGQGQLPMDPFEANRTFYGVDLTLYVDRRPLVINSLLERAMEWCSQGAIQPIKPVKYFEAHQAEDVLRGMQSGQHIGKLVVRFPTDHTQVSASRGTNRMFLGPDVSYFLVGGLGGLGRSILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KE17</accession>
    <name>A0A5N6KE17_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_003466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KE17"/>
    <dbReference type="OrthoDB" id="10254945at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8301625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="423" mass="45955" checksum="86B632A694052190" modified="2020-04-22" version="1">MAPQEDLLLGDEGESGSLMDDDDGDDGMGRGSMNRENSMAENSNNGNRPPTHTQYSDSSPSATHPPITTTTYKSITSTDIAITSAFSTSNMSGISATLSMSTFIYPSAPKTTSQMTTTESSSLSLKTSTSTPFPDTGASTQPISVISIPQRKSTHHSLTNASIAGLTIGILFIFSLILAVLWYFLQQQKKNKNLRKSIGGFDAVKWNGAGISENEKQQVPPFKGSVKTGMSIQRVLSWSTMRGLTHSRTRSSISETSSISSQETLGNPAADQKSSVSRLRNGSTGTARDGTGKDEKREGGHEYFVDFGDPTEWIRNKKRRDREGNGLALGGPGQGLVDWRYSVRVNGGYKYLYLCWYNPRCYSLCDLWNGELYNSPRGASTPNAVRRIIRTATQKSHGPFPDTVSISKVDTVHILAPPSLTHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFN1</accession>
    <name>A0A5N6KFN1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_005965</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFN1"/>
    <dbReference type="OrthoDB" id="20582at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019163">
        <property type="entry name" value="THO_Thoc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375">
        <property type="entry name" value="FMS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375:SF3">
        <property type="entry name" value="THO COMPLEX SUBUNIT 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09766">
        <property type="entry name" value="FmiP_Thoc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8302586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="145" mass="16401" checksum="11A7650C6601B6A9" modified="2020-04-22" version="1">MSIDEIITDPSLKLALETSNQTREQAIALLDFVSTASTTSPPSNEVLLQISKQQKLLLTYLAQLRGLHRDSHAGARETKALTAEARQEVDRLHLQLQNLYYEQRHLQGEIAACESYELVSWQFSLFEVWYPANATFSVTNTSSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFN2</accession>
    <name>A0A5N6KFN2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">CCT-beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_005895</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFN2"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000002">
        <property type="entry name" value="T-complex protein 1 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012716">
        <property type="entry name" value="Chap_CCT_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02341">
        <property type="entry name" value="chap_CCT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025052376" description="CCT-beta" evidence="8">
        <location>
            <begin position="21"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8302497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="442" mass="47541" checksum="D9E8214F135E00C9" modified="2020-04-22" version="1">MTKLATGLHLLQIASQAALAALEKSAVDHSSNAEAFRKDLLAIARTTLSSKVLSQDRVQFAELAVDAVLRMKGSSDLSHIQIIKKAGGKLSDSYLDEGFILDKKIGVNQPKRLEKAKILVANTAMDTDKIKIFGARVKVGSTGKLAELEKAEKDKMKAKVDKIKAHGINCFINRQLIYNWPEQLFSDAGIMSIEHADFDGIERLALVTGGEITSTFDHPDQVKLGHCDLIEEVIIGEDTLIKFSGVAAGQACTIVLRGATEQLLDEAERSLHDALAVLSQTVKEPRTTLGGGCAEMLMAKAVEGAAVKVDGKKQIAVGSFAVALRQLPTILADNAGYDSSDLVARLRSAIYDGMSTYGLDLLTPGGGIADMRELGVIESYKLKKAVVSSASEAAEVTSPQSGQYHSQCPTETRKMSVMKEEKNDDCIMKMQTCSRGFVATIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFT0</accession>
    <name>A0A5N6KFT0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_005916</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFT0"/>
    <dbReference type="OrthoDB" id="5344169at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11392">
        <property type="entry name" value="bHLH_ScPHO4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="316"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="345"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="394"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="352"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="371"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8302525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="421" mass="44607" checksum="8B3843937BFDB1ED" modified="2020-04-22" version="1">MNCDSHSAPASSNLPSRKPTRKSVAPKPRVNNRAVRQSPIVKPNRNRKSTSMNAQALGEIIDFQTSKSKGTGPTNSAASTDHSENGSISPEHLSDMAPPPLPSSAGRSPYVVAQNDNVKNKLLPLDSPATPASLMRIIKSPTATESTLNQEMELDDPALDGFSLPEAATTIRPVLPRIDTQSDGQTTPTLHTIGSQTPGFQPLPSPVIAHPGASSSINQSPQIDAMNGINGAARKTPQTLARGSKKRTSKSVLASPALLPKISPSIKPLLPGGSPLHNDAAASLLLASKSNYQKILEGTHLPGVSYPSELSTNLTLKRTSHKLAEQGRRNRINLAITTLHDMIPSEYYPRGKSKDAVEDKGGSGDAGENEPASSKGGQSSNSKAATVEVAIEYISHLEKVLAEANKRAEEAEQKLVEKEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFT1</accession>
    <name>A0A5N6KFT1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFT1"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="111" mass="12993" checksum="C5561F9B5C5B459C" modified="2020-04-22" version="1">MYERVVRLAVYSILILCCTVSIYLHYTPYKLYNTYHNYYTILLIQTLSKMHDLFSFTSLQEFKAPQPPPSIHPFPHSSIPSFKFLSPPFKNPTHFFIYLSSIPSTKTQHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFU2</accession>
    <name>A0A5N6KFU2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFU2"/>
    <dbReference type="OrthoDB" id="5144514at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006771">
        <property type="entry name" value="CetA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36195">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01990)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36195:SF6">
        <property type="entry name" value="SECRETED THAUMATIN-LIKE PROTEIN CALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04681">
        <property type="entry name" value="Bys1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="158" mass="16718" checksum="93EBAC8F5C180480" modified="2020-04-22" version="1">MFISTTPNASPWHIKAGKGASSTLTLPWDTDGHGTSIKIAKTSNWKTTPSILQFEYAWTTGQYAALYWDLSDLDGSGSGLVGTPFMKDNVKVSPTGTGSGSGTCVKLKCPAGALCKDAYNTPDQEATRSCPLSTGTIWLDLCEPAGGFNSKREIGFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFU5</accession>
    <name>A0A5N6KFU5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFU5"/>
    <dbReference type="OrthoDB" id="10027013at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF10">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="54"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="315" mass="35221" checksum="5A3B98417D8913E6" modified="2020-04-22" version="1">MSVFNSTNSDPTFRNYTTEQAKRYAAHRLSYPSKLYETVTSHHEKTGGQFNLVLDLACGPGNATRHIAAYFEDAIGCDAGLAMIETAREIGGETKSGRDIRWVVGSGEEFVKLDEVEEGSVDLITVAMAVHWFDMDKFWAQAAKALKPGGTVAVWTRASYYPHPSTPNRDELLRIFLHFEREVLGPYELLPNRLSRDMYDHLPLPWNIPHPIPSSILPESQFLKLDYDRDGILSDPSSNNFFGGGREVTLMQAEKGLSTASMVTRWRETHPKKAGNEKDILKLHIEEVRKVMGGGESMITGNSTTIIFVKKAVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFU7</accession>
    <name>A0A5N6KFU7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFU7"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052370">
        <property type="entry name" value="Meta-cleavage_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43139:SF65">
        <property type="entry name" value="HYDROLASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43139">
        <property type="entry name" value="SI:DKEY-122A22.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="129"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="421" mass="46390" checksum="F30F2AA86572D432" modified="2020-04-22" version="1">MLSPVTIPESLNSIHKVFTNIVPNHSLGIPLSLFAGLATTSLFFLTFRDVYFTGDVTKIASWEKKSDLEPKSKSKIVPSPLTTQIPTLSRGEIFALPYPPDIFPGARDIPSPYGSTRAYEFGPLTGPKVLLIHGISTPCISLHSLATTLASSHGCRVLLFDLFGRGYSDGVADLPHDERLYTAQILLVLTSSSLSWVGDGFNILGFSMGGGVAVDFAVGFPEMVQSVVLLAPGGLIREEQFDWKGKMEDDDQGQVDSELTTAIPSSSLARRTDTRISFDETPISPSLPHITVGEVMCWQTQRHRGYANAFASSIMYASISGCEETWRRLWGSRDCRTSQEDSKSRIREKILVVVGEWDDVIVPEELKEDLERMADSIDTGDDRRWNFDERVVWEVVKGAGHEFPITKGEEVAGLVGKFLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KG00</accession>
    <name>A0A5N6KG00_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_006066</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KG00"/>
    <dbReference type="OrthoDB" id="2110422at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8302706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="101" mass="11380" checksum="BB7A1EF9DF00B028" modified="2020-04-22" version="1">MWDDDDDDDDDDGYGGAGNDMIGMGMSFQIQDFYLSLKSSSTSIWQLAIRLLIDGEGASRDSQSGYCLRIYIRTYVYLQVLISNTSTLQSFFSLLFVNTVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KG09</accession>
    <name>A0A5N6KG09_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KG09"/>
    <dbReference type="OrthoDB" id="5294180at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF12">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="248" mass="27238" checksum="5AFBFE596F5900FE" modified="2020-04-22" version="1">MSFNMTLTAWIDILGSTVQGRAPTFAHTYREKHLSQTNSSLGLRELMGCEDRVLYLISEIACLEALKNDGMDDIQLCQHVHALGDQIGLTEIGETGPRIPYNSHGVLSPKQLSRNMTAAFRLAARIYLCSLVPGFSPSQESCVGLVAKLTQVLEFIPAGPVGFDRSLVWVYLIGGSVSTTNSPFRQYFAERAAALGDLADHGSFGRVSTLLKEVWGHVDGRFSPGGGEAHYVSWRDVMQMKGWDFLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KG58</accession>
    <name>A0A5N6KG58_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_006012</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KG58"/>
    <dbReference type="OrthoDB" id="47494at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8302645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="211" mass="23779" checksum="E2362E791FB557C1" modified="2020-04-22" version="1">MRLASFTASDTTVTVKFEDGTSTSGTHLVGADGAKSLLRTSLLGDTAALTPMPYTMYNFKASFTAEQARYLKETSSFHPIMNFGTNKELKIFSMISILDVVDRKKPETWIFQLLWSVFEEDPKHREKVATMSNEEKLRFLQSNADLWADPWKSALKWVPEGTEIPADVCMLWKDPVLWDNHQGRVTLAGDAAHAMPPRKYPIPPLSIDALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHS3</accession>
    <name>A0A5N6KHS3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_004592</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHS3"/>
    <dbReference type="OrthoDB" id="1706066at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050218">
        <property type="term" value="F:propionate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43347">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43347:SF3">
        <property type="entry name" value="ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="4">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="79"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="3">
        <location>
            <begin position="557"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8303141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="690" mass="75986" checksum="AF1CE098DD53BEB1" modified="2020-04-22" version="1">MYTDKMPFYPQDEVQSQSLSDPQSFWAKQASYLHWHKPPTQILTEKTKTLKSGTEHKHWEWFGDGEISTCYNCVDRHVLAGNGEKTAIIWDSPVTSCKEKISYRELLREVEVFAGVLREEWVNRGDVVLVYMPMIPAAIIGILAISRLGAIHAVVFGGFASTSLAQRIEASKPVAILTASCGIDGAKPPLSYQPFVTEAISLSSHKPRKTIIWQREQLRWENPNKEKGERNWQRLVKSAASRGVEADCVPVKSTDGLYIIYTSGTTGLPKGVLREAGGHAVGLNLSISYVFGIHGPGDVMFCASDIGWVVGHSYILYAPLLAGATTVLFEGKPVGMPNAGTFWRIIDEYKVNTLFTAPTALRAIRRDDSENKLFKEIGERGGLKSLRALFLAGERSEPSIITMYQELLARYAAKGSNVIDNWWSSESGSPMTGIALSPRTALSRTSHKTGPIIPIKPGSAGKPLPGFDVRIVDDSGNEVPCGTMGNIVLGIPLAPTGFRTLWGDEERFYKGYMKRFGGRWIDTGDAGMVDEGGWISVMSRSDDIINVASHRFSTGTIEQAISTHPLVTECCVVGIPDSLKGHMPFAFITLSTPTHPVSAIPDIELEKEIQGLVRRQIGAIAHLGGIIQGRNMIPKTRSENEYYGDGGKRVNVPATIEDEGVVEVAREKVREYFESKGREMEEKMERKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHS6</accession>
    <name>A0A5N6KHS6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_004691</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHS6"/>
    <dbReference type="OrthoDB" id="18894at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="436"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="466"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="494"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="10">
        <location>
            <begin position="311"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="25"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="525"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="95"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="525"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="540"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8303247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="598" mass="66152" checksum="D303D9F37136A863" modified="2020-04-22" version="1">MALEETAFKISAQHHSQLEEEEITTAFTPTPTVTSPHTDTPHTHTHTHTTTTTTTTTTIPISDQTSIPDTSFESSHSHSHPQSNPHPHPHPHPHPYYNSISISNQPSQSHFPIKTLSRTSTSEASTRSEEELLEPDAATALADLRPTDPNMNPQPSGHRRRRSSMMNNLDTSSRAPRAKRSPRSATFGGDSKLGDRVSDDDSRSTSDDMELNNFSEEGDLQDDEETGLTAKSKAKRKKKKIRNQSMDHRIVGDNIVTKDEKKEADWNVVRKSLMNGVLISLWYIFSLSISIYNKWMFDPNHLNFHFPLFTTSMCKSSALAFVLLFAFVFRLETPSWRLVGIIFTMTIGVVMMVFGEVDFSTKGFVLVIFAAFFSGFRWGLTQILLLRNPATSNPFSSIFYLAPIMFASLLIIATPVEGFPALWEGLQVLVEVKGPIFGPLLLLFPGCIAFCMTASEFALLQRTSVVTLSIAGIFKEVVTISAAGIVFHDPLTPINISGLFVTIGAIAAYNWIKIRKMREDAQNEARRIHEATERARESGSDADGEDGESDWDGQEGNYVTSDGGVLPNPDRFQAKKGESSRAESAPLVGGSSKKDLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHS7</accession>
    <name>A0A5N6KHS7_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004762</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHS7"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="138" mass="15277" checksum="86E77D2BD494D365" modified="2020-04-22" version="1">MATFLICTAVSRIKSTTHQFGKGLRITFVFSDIGGSYCSLLLPTHNFEVEAVKLQSHRCALRLFVSEVITSVGSDYSHQNISWNCIHGATQLGLGRYIVGQIRANTVASKIQSIYTLPSYVIYFITLVPVKILNAHVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHX1</accession>
    <name>A0A5N6KHX1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHX1"/>
    <dbReference type="OrthoDB" id="10259622at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="226" mass="25476" checksum="3370F05EFA9AB002" modified="2020-04-22" version="1">MPSIAQEDWDIAPSMDLHTSPNVNLLKRRRDVANVMDREELLEEVQMKMNSSRLTHLHSHSHPHNLYPHIHHEPERRHLVPRSKMSMNKRARVECVTAETGSRVEQVREKEKVAGSGTGIGAGGMDLRPCHICRRKPTVKKELDSFANCEGCGKRSCWVCIRECLGAWGNQMGMEGEDKGSEEEGKESWAENGTQHRGMVCSRCCVERGTEGEVLCLGCLRMEETG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHY3</accession>
    <name>A0A5N6KHY3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCAAT-binding factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_004750</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHY3"/>
    <dbReference type="OrthoDB" id="10263185at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030692">
        <property type="term" value="C:Noc4p-Nop14p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027193">
        <property type="entry name" value="Noc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455:SF0">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="3">
        <location>
            <begin position="317"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8303312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="387" mass="44099" checksum="1DA81FD5308774E9" modified="2020-04-22" version="1">MPGKILDTKRASKRKRDVSEKGPSKRARSESSEEDSQAQILLLESEIFESKKNYNNIARLIGIARDDSEGADASILAAISLCRVFTKLIVVGGFQKTKDTSVKDATVIQWLKERYSEYKIVLLDMLSQEDAASTALTLCMRMLKIEGQHMRNGQDYCFPIGLLTDMIQVLIRPGSDSSVRKEFSEKFVEEYDDVRFYTLEAIQKLVTTPKDQHLECDSFDAVYEVLTSISSVPESKDELEDFYIPAPKKKAHALYSLTEHKKRAQGAWLAVMNMEMVKERRKLILSKITESIAPWFTKPELLMDFLTDSYNSGGSTSLLSLSGVFYLIQEKNLDYPSFYRKLYSLLDTGILHSKHRSSTCRKLYQETIPTHVTLPSFWCRCGRAVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI37</accession>
    <name>A0A5N6KI37_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI37"/>
    <dbReference type="OrthoDB" id="442460at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="57996" checksum="BE46176ADFB91339" modified="2020-04-22" version="1">MVAEIKAKKQISITPPKTLGMTAKTQAKDDHTGLYTGTGLPLQGNYCDCGVYLLSYMEEFFERPDGFIEDIVENKYKVESNRNNTPEFRVKIRDILFRLQAEQAVEPEVAKKARKAKKSKAAPLMAGNKVERPNPQTESLSISSRGQKQSASAPSTLNLGCNNGNLTGAAARTSPDSLPISKRKEVINIEDSQNSLREQLEEEFASNRVNDSNYRAIEDKPKSRGCGRETREAARTTVESGPSERSAHFGIRDSFEEQESTQESANHRSMTQQQQSKRKSSILDLDRDESHIDDDLPRQISRGTRTLVGNALGYCKAAFQATTKDSVGPAASKDEGDQRNPTSKSRKQDALQSSLESPSRSGSNSPRQLENNARLRQGAQDLRSPSPEQIDSKYSRSRRMDSNGSNHIDLVNSLEIRQGDVNQVDLTEDDPDEMLLDQRSLHFPDVPTFPHSPLAAASRKRHRSNNQVPAEALLDRKAAELRRGDEDGAPRLFRHADLEGFANKQLTGRDPAEAKMIAQSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI38</accession>
    <name>A0A5N6KI38_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Altered inheritance of mitochondria protein 41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AIM41</name>
        <name evidence="2" type="ORF">EYC80_004859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI38"/>
    <dbReference type="OrthoDB" id="538640at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="entry name" value="Uncharacterised protein YqeY/AIM41 PF09424, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 41, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 41, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="GatB/YqeY motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="145" mass="15918" checksum="B053C4E05EC4948A" modified="2020-04-22" version="1">MKTAMKNKDTNRLSVLRSLLSQTLNASKTSSPINTDMQMLALLRKSANASRAASEEFKAAGREDLVEKEESQLKVLEEYAGSVETVGEEEIRSTVKELVNSMKANGAKMQMGDVLKRVFTPEVLGEKNVEKGEVAKIVKEVLAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI40</accession>
    <name>A0A5N6KI40_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Carbon catabolite repression protein B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Deubiquitinating enzyme creB</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin thioesterase creB</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ubiquitin-hydrolyzing enzyme creB</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Ubiquitin-specific-processing protease creB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">EYC80_004802</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Ubiquitin thioesterase component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Deubiquitinates the creA catabolic repressor and the quinate permease qutD. Also plays a role in response to carbon starvation and the control of extracellular proteases activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Interacts with creA, creC and qutD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI40"/>
    <dbReference type="OrthoDB" id="27652at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF733">
        <property type="entry name" value="RE52890P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="USP" evidence="15">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="213"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="230"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="318"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="365"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="405"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAB8303372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="434" mass="48248" checksum="A395B6B072A6518E" modified="2020-04-22" version="1">MLCEKNKFHCDTCGGLQEAEKRMKIKTLPKVLVLHLKRFKWTDDLTRLQKLFYTVNYPYHLRMFNTTDDAEDPDRLYELYAVVVHIGTNAFHGHYVAVIKTEDRGWLLFDDEMVEPVDKSFVRQFFGDKPGQACAYVLFYRETTVEAMRRDQEAEGLDLNAAAPEVADLAPGNPQQNGTHPRQILATPLTPIDTETNGFGSLDHAATAPLVASPISGNPIPSRIPTSPLDTHKLKTKEEKGRERKAEKEAEKAEKEAEKSRKAAEKAAEKAAAKERKEAEKASKEAEKASKAQEAEMRKAIALSKQTETEEVKRRQSEASNQRENNGTGSEKSESKGFGSLSLNRTHKGSKSMSRKSLGFLSGKNGEKEKEKEKEKNGENANIPESSSSANVNTAVEGMAGPQTPEKHEKIKKERFSFGGLGRKKSNLWSPGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI44</accession>
    <name>A0A5N6KI44_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI44"/>
    <dbReference type="OrthoDB" id="5573651at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="100" mass="11094" checksum="C767484ED2AC46BE" modified="2020-04-22" version="1">MLNSHLVTDTRSHPKSLSRIGNFLNTPPIKTSQAISQGKFTPIPTLPHIPLISTPRLYPQVISAPGFPVPAEPFGCKSSPRTSFMYDLSNCSIRRFNSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI46</accession>
    <name>A0A5N6KI46_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_006232</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI46"/>
    <dbReference type="OrthoDB" id="441771at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030692">
        <property type="term" value="C:Noc4p-Nop14p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007276">
        <property type="entry name" value="Nop14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23183">
        <property type="entry name" value="NOP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23183:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04147">
        <property type="entry name" value="Nop14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="116"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8302909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="196" mass="22096" checksum="05FFDD0A271F78B7" modified="2020-04-22" version="1">MPPSQLKRLKASLREQGIVGPQQSKKQKKQNAQNGVNKEKKIKRSVALNGIRDQFNPFEIKQSKAPKFEVTSNKTLSGRISKGIKKPGVARGLAEENRRKTLLLEMQRRNRVGGIIDKRFGENDPSMAPEDKMLERFTQEKQRGHKNSSAFDLEDDDTPGELTHMGQSLSLDGPTIRDDYDGEDLELSDADDHERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI99</accession>
    <name>A0A5N6KI99_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004764</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI99"/>
    <dbReference type="OrthoDB" id="3647690at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070823">
        <property type="term" value="C:HDA1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038609">
        <property type="entry name" value="HDA1_su2/3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021006">
        <property type="entry name" value="Hda2/3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11496">
        <property type="entry name" value="HDA2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="427"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="276"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="433"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="458"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8303331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="493" mass="55299" checksum="CBF8EF55323B2A9F" modified="2020-04-22" version="1">MIMPGNPGEPEKDLMQVTLLPTWIDVRDCIVAPASVVVAFDSSFSESQGGDEYYQIMPFDPRNPDKRAPLLWLVTANSVEHVELCIPTTLESSERKDRLVQYVTQTRKVVGLLDTNTYPDPQQAARRAAEYVMDDSLEAEWPINPMPDIEIASFDNRANNRLTNSMAQSLFSPIEPTGQSGYKRPSDFDAEYEDTAIKRQRMTPTKQGRQPDINIMDGNMVELQNTITTLYARCEDYEKSIKRIQPKFQRALDERARFEHENAQAVKHQSEYEKKLGAQDEVAAKLREENAVLKNELSVARNSLLASANPSIAEYHKTKEDIRTAQAEIERLKKAQASAEKRADYAASLYQESSQQAQEMRNELTTLKSQCKELQRQASAARIEINKTNHDGIIQQQVDVIDDLRRELAERERHLGVVSGQLDACMNGRRTTRGTSVPRSPRMSNMSPRPRVLGSMAPGSNTASRGNSPAPGVFGGDLFQGGDAGRRFGAHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJW0</accession>
    <name>A0A5N6KJW0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">alpha-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">EYC80_005329</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="4"/>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJW0"/>
    <dbReference type="OrthoDB" id="3237269at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017177">
        <property type="term" value="C:glucosidase II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06603">
        <property type="entry name" value="GH31_GANC_GANAB_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000023">
        <property type="entry name" value="neutral alpha-glucosidase AB isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033403">
        <property type="entry name" value="DUF5110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF54">
        <property type="entry name" value="BCDNA.GH04962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17137">
        <property type="entry name" value="DUF5110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="10">
        <location>
            <begin position="76"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="12">
        <location>
            <begin position="410"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5110" evidence="11">
        <location>
            <begin position="521"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAB8303975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="648" mass="73592" checksum="01895591945E940F" modified="2020-04-22" version="1">MQAHKASSTVGVFWLNAAETWIDITKEKESINPLSGKTKTKTHWFSESGLLDVFVFLGPTPKDVTKAYGELTGYTQLPQEFSIGYHQCRWNYVTDEDVKDVDRKMDKFQIPYDVIWLDIEYTDGKKYFTWDPHTFGNHVDMLSHLDKSERKLVAIIDPHIKNEANYHIVDELKSKDLAAKNKDGVIYEGWCWPGSSHWVDAFNPAAIKWWKELFTKDAWKTSNLFIWNDMNEPSVFNGPETTMPKDNLHHGNWEHRDVHNINGLTFHNATYEAMVERKKGELRRPFVLTRSFYAGSQRLGAMWTGDNQANWDHLAAAFPMILNNGIAGFPFAGADVGGFFGNTEKDLLARWYQAGAFYPFFRGHAHIDTRRREPYLIGEPYTGIITQALRLRYALLPAWYTAFHEASTDGTPIIRPHYFEYPEDESGFAIDDQFFVGSTGLLAKPVVTEGAESVEIYLPNNEVYYDYFDYSIHTGAGKTTIAAPLEKIPLLMQGGHIIPRKDRPRRSSGLMRWDPYTLVLALDKNGKAQGELYVDDGESFDYQSGAYIHRSFSFEDGKLSSKDIGTKGKLTDKYLKSMKKIGVEKIIIVGAPKAWSELKTVKVGSGTAEITYHAEEGNKAAWALVRAPKVAIGEDFEVEFAEDGKTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2024-05-29" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJW8</accession>
    <name>A0A5N6KJW8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005337</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJW8"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="72" mass="8511" checksum="0464B171C98DEA29" modified="2020-04-22" version="1">MPFLPIQVYKAPPHLVGSCQYQYQYQYQSSFLILFTGSGCFRIIFSHPYPYLLDGDDDVTFFEHYTRIVIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJW9</accession>
    <name>A0A5N6KJW9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJW9"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="152" mass="17455" checksum="EB13331A4CC2F10F" modified="2020-04-22" version="1">MEIREMEGIVLYCSAIWIFDAQGDRIEGENIRARYVPPAPRTTHQPKITNNATPFPITKGGRVEKSKTPTKPHMYITHQPTTRPISETSQRSFGDGKVKAKTSVVNINSQPKTQRKKERKKERKKERKKEHPSSQATRRASPYKAWSMRIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KK82</accession>
    <name>A0A5N6KK82_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_005351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8304001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KK82"/>
    <dbReference type="OrthoDB" id="5393537at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="72"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="165" mass="19329" checksum="AAB5F2587A0DA266" modified="2020-04-22" version="1">MENMRIEVSSQIQTIHVSVDGHSTRTSSGSRGILSRLMPGSENTNPFEEDTEDWKKKNLKSKEDYRILETEKVQDTKTIQDLRSQLKRVEEDHRETRMQLENMGIKNRQLQEQTQIFRGMIINRGSSNDDVVDDNTIIKDFVALRDQIQRIVNRYYKCEARPPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KK84</accession>
    <name>A0A5N6KK84_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_003532</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KK84"/>
    <dbReference type="OrthoDB" id="417877at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8304112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="29015" checksum="70E7A3A8F0E87478" modified="2020-04-22" version="1">MEDEQQVMDSKLNVAIIGGGLGGLALTIGLLPYRDHLNVSIYEAAPCFAEIGAGVASGPNAVHALGLISPDILERYRKCATFNETRDRDNVWLSFRYGMDSKNEDGKKLDLIYHSGEKGKSLGDISEMLTREEIRRRSCVHRARFLDEMAALVPDGIAKFEKNLVDVKELGGDKEALELIFEDGEIAFADVVIGCDGIKSATRKYVMENQSIEPHFADTYAYRAMVPRNIARNAMGDDLTLNARRFDQHGCIKEDEGHWMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KLZ4</accession>
    <name>A0A5N6KLZ4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_004125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KLZ4"/>
    <dbReference type="OrthoDB" id="4179406at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8304776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="277" mass="31470" checksum="CFDA46B5ABDEBAE3" modified="2020-04-22" version="1">MRGGRPTLQLGESWVVEGHDEHEEYLPLNEVDYDHRARTSTPRRSIRGNNRSPDPEFVMPSLDAETLEASWSQGESTSRSPRRFQESRRRNSRHDLDHENLTKRPRTQQAHDRSPLVPSTTNSNTPHHPNSDMKDVITVFFDHVMAAFTWILEILGGALRLLRTPLSYLLAISILYGFALVARSLFTTSIYASLSPICRLPGLSLLSLPFCSVYNGDSSNGARFPVEFEQVMIVQSQFEDILKESAGGVSLPLDMKRGESFLRDLRQLVRYSQLKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMA0</accession>
    <name>A0A5N6KMA0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMA0"/>
    <dbReference type="OrthoDB" id="1708534at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8304757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="90" mass="10595" checksum="D4CDD1363D604394" modified="2020-04-22" version="1">MPKMKVDPENYRVEADGVHIICEAADWLPLGQNAGLGSLRMRCKERIRNLYECYFFHNTNTTTKRTFENANLSHLREMSTRCMMSCEKQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMB2</accession>
    <name>A0A5N6KMB2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMB2"/>
    <dbReference type="OrthoDB" id="1232at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8304761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="75" mass="8471" checksum="1D67197810441911" modified="2020-04-22" version="1">MTKTLMEKRQKWIKNIGAVFDDERNLGKVPRARDEGSSIFKPEFCSYSVKERGPGTAAGFLRIMICLQIHPPDCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMB5</accession>
    <name>A0A5N6KMB5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Catalase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_004292</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMB5"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF62">
        <property type="entry name" value="CATALASE T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="7">
        <location>
            <begin position="1"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8304980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="490" mass="55591" checksum="9FF26FDB14212647" modified="2020-04-22" version="1">MFKEGKECPITVRFSTVGGESGSHDCARDPRGFSVKFKTDEGNWDLVANNTPVFFLRDPAKFPHFIHTQKRDPSTHLTHADDSTMFWDYLSQNPESVHQVMILMGDRGIPDGWRHMHGYFGHTIKLVNKAGEWVYCQFHMISQQGTKFFTQEESAEKSPDYAQKDLYEAIERGDFPKWSLEVQTMTAKEAEDLWEKEKINVFDLTHLTLNENATNYFAEIEQVAFNPAHLVPGLEPSADPVLQSRLFSYPDAHRHRVGVNYQQLPVNAPRTSYRMGNFQRDGSMAFYNQGSRPNYISSIEPIHFQERTVNTDKVHGHFTGTAVTFLSEIRPEDFKAPRALWENVFDAPAKDRFIKNISGHMANCTQDEPIKRQIAIFREVSEDLASRLEKATGITGYPGIADLSFSGTHNGMARERAHRTANGMKGVALRHSESNGAPKRGSHATVGNVGICNSLHLFPCSRMKVIWYAQFMYIATPSKHNIGICNELSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KMB6</accession>
    <name>A0A5N6KMB6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_004294</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000001">
        <property type="protein sequence ID" value="KAB8304984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KMB6"/>
    <dbReference type="OrthoDB" id="19711at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050995">
        <property type="entry name" value="WD-F-box_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604:SF4">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604">
        <property type="entry name" value="WD40 REPEAT PF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="128"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="169"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="285"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="325"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="499"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="588"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="603"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8304984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="674" mass="74142" checksum="13685B266C1C0288" modified="2020-04-22" version="1">MTSSVDGKNDDEDLTVVKQPSMFGSTSGWEMKQSPLAEDSIMMDAPVCPTAGNRDRTTETAAFQGTGKGKGKSASQSRKSFTLAILDRSDGQEKLNWHFLYTQRRRLEANWDAGKSTNFQLPHPHYPEEGHTECIYTIQHVDNALVSGSRDKTIRIWNLETRRLALPPLREHEGSVLCLQFDPDPEEDLIVSGSSDATIILWRFSTGKLIQRLKAAHRESVLNVKFDKRVLVTCSKDKTIKVFNRHPLSGNKIANTASFQISSLGLADPTAGACILKPYTHLRTLQGHGAAVNAVQILGDEVVSASGDRTVKVWDWRKGTCIRTLLGHNKGIACVQYDGRRIVSGSSDNEVKVFDKESGLEVASLRGHTNLVRTVQAGFGDLPFSAEEEREDARRIDREYFQALDGGLFKQSHQPGRPRNAGSSRPEHITAFGAKLPPGGGGCKYSRIVSGSYDESIFIWRRDKEGVWKTQHVLRQEQASRAAIRAAVSIPRKPNKNSAWLLPDPSSVTPSANPETPLKDVSSLGPEAQIDNAIAAGAIGLRQALIDYPNLLDSEYLRIAINRLTDHTKHYLNVVLIAALQAKGYDVSDFPSSDDESTTTEAPAPPNSSALPPPVGNVPVTAHGQHPMHARVFKLQFDARRIICCSQTPIIVGWDFANGDEDIIEASRFFAPME</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JRK3</accession>
    <name>A0A5N6JRK3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_010078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000015">
        <property type="protein sequence ID" value="KAB8291402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JRK3"/>
    <dbReference type="OrthoDB" id="409121at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8291402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="76" mass="8859" checksum="DB9EFD60B2649A45" modified="2020-04-22" version="1">MVLGWWLGIRKGVFFSLSFVLLCCCVQLLKGRRKEKKKERKGKERKGKERKGKERKGKERKGKGKEKQANHTSSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JTN5</accession>
    <name>A0A5N6JTN5_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RecA family profile 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_008162</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JTN5"/>
    <dbReference type="OrthoDB" id="5957327at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033063">
        <property type="term" value="C:Rad51B-Rad51C-Rad51D-XRCC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033065">
        <property type="term" value="C:Rad51C-XRCC3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000707">
        <property type="term" value="P:meiotic DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052093">
        <property type="entry name" value="HR_Repair_Mediator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="284"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="284"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="361"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="377"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8292439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="442" mass="49189" checksum="73D343BE9DBF322F" modified="2020-04-22" version="1">MDYQTIHGLGRSNFSSSSPHRMPTVSAAQALQELESSLTRWISTGLKNLDLALQNEDSLQLSTSVDENYGGISRGRITEVYGPPGVGKTALGMHLAAKVLYQNEDVVWMHHIQYQVLDSVKSYKHFHLQNLPIIVKSSKDSFSTLIDSAFPRKLDSTPTPRKPGAPNPSSRKFPLLQYLINALQKLATTRNIAIIILNQCVTKMRPGLGAALIPSISVTAWEQGLGCRVALFRDWGWDDNEGNKVNGVRFAQVVKAEGVALSEGRGRFAAFVIGELGLSSATLPPPPTFASPNRGPPSFPKLQPTIALPPQKRKRAEFEIPDSDDEDDEDYGWAEEDEELPPMPPQWQGSEDILVPPPGELEAEEEVEEAEEEEEKEKEKEKVKEKVKEKEKEEDIVNGNEKGREANVDGENHREESPREKYSAGVYERDRELPDSEDELAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JU12</accession>
    <name>A0A5N6JU12_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_008266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JU12"/>
    <dbReference type="OrthoDB" id="10265891at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF31">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8292558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="188" mass="20748" checksum="CC102B9D57D9B04E" modified="2020-04-22" version="1">MLGASAVWVGTRFILTDEAGASKAHQEAVRTAGHDDNIRTIIFTGRPLRIKELTSKGVIPVEHDFETLGDDIDDETMDNARPFLMGKAAAVVNEKKSAKAVVDELVSDAVACIHKGEKLTAKLIDSEIVKLIVHEQLVSSHQALACKERHSSFKMLTRILNRTGYGSFDIFSSYTINDNDNINIITFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JVS2</accession>
    <name>A0A5N6JVS2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_008272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JVS2"/>
    <dbReference type="OrthoDB" id="9981546at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="23"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8292564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="338" mass="38433" checksum="472B5EBCB65A6794" modified="2020-04-22" version="1">MSVFLYTPYSLIISKLNNMVDSFTGIASLPNELLINSLSLLSTRELLPIASTCKRFHNSIIRIIHHRLLAASSLKDFKLVLECYHPSTRLDTPHLFCDYIGTDGLSDDFGREEDLYKEVEDTGRLGKMFSLYSHFRPVQPEKRMVWKKSPAGGARPDLLSKSQEELVSQDIDLESYEYFSQLCTNTRLAKVEQKGGSFKSCGNLGEGVLRVFRGWLSDRAEANERHVDTPEERENRLLWAGAEKNVGLRLKVLKQEEAPEPIMLGRDEEPPVFYKLQYEELVIRTTQLLLSIEDSLTREVQNSGMTCSRDGVNQTSALSSKIKAMETNYSKMWTHGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JVS4</accession>
    <name>A0A5N6JVS4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">EYC80_008280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000013">
        <property type="protein sequence ID" value="KAB8292574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JVS4"/>
    <dbReference type="OrthoDB" id="5329176at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF108">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="37"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8292574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="367" mass="40965" checksum="931E1AAC3CA8797D" modified="2020-04-22" version="1">MDMGAVNVADLPHDSRQAQAFTITFVFPVIATVALALRMYSRSLTRSFGADDWVICFAMVVYWAETYTSYKVIIYNCIGIHVWDIPPDWNRVIGAKYAYATELIYNPILALVKTSILLFLLRLTGQKTNVRRTIIGLLIFNGLMMVTTFLVTTFHCIPIAANWYPDLYPNAVCMNFSDFVTGTASIQRKQKFMLIGILSLGFVTVIVGIIRIILLDDFDRHPPPDVSYSLVFCITTVEVGMAFVCACAPALKPIFVRIIPKIFGESSRSRSAKKSTEGYGRTGRRPEGYEMSRRVAQHTTDIGAGDEDYDRMSDLTDVQGGHGKDDGHKDRMEIAVRTETEVKWHNNVSVGKGKAARKSGSSTENLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW34</accession>
    <name>A0A5N6JW34_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_007495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW34"/>
    <dbReference type="OrthoDB" id="448573at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8293147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="70" mass="7974" checksum="0803222E32DE3B9E" modified="2020-04-22" version="1">MGKVAVEGSKGNKHTRHGGRMEMMYSAREPCLAITFGWVHDFTLEQVPHGEICITCCPTFHNFPIVHRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW47</accession>
    <name>A0A5N6JW47_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="5">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">EYC80_007495</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="17">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="5"/>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW47"/>
    <dbReference type="OrthoDB" id="448573at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006659">
        <property type="term" value="P:phosphatidylserine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1760:FF:000022">
        <property type="entry name" value="CDP-diacylglycerol--serine O-phosphatidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF61">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00060701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAB8293145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="308" mass="33965" checksum="01C0066665EE73F8" modified="2020-04-22" version="1">MAMGTEEKKKKKKKEGIPMERDIFDVNEYSIPPRKPLPAKSQKPTISRYLTTFSVHFKSAVRVCISQMSKRNSNNAANGATKDSTVGGPAEDKQKRLLEKDTGHFSMIKMLHLADLITELNGFCGVMSVFSSMRYCLGPHDAYGNLWAALAFMPFGLFFDFMDGKVARWRKKSSLMGQELDSLADLVSFGISPAAAAFAIGLRTPVDHFFLAFFVLCGLTRLARFNITVANVPKDATGKSKYFEGTPIPTSLSIAALMAYWVSKGWVLDNIPLGTVGAGTVFEFHPVVGLFVLWGCMMTSKTIHIPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW53</accession>
    <name>A0A5N6JW53_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Centrosomin N-terminal motif 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_007516</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW53"/>
    <dbReference type="OrthoDB" id="10255000at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012943">
        <property type="entry name" value="Cnn_1N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07989">
        <property type="entry name" value="Cnn_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomin N-terminal motif 1" evidence="5">
        <location>
            <begin position="130"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="76"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="670"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="181"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8293169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="691" mass="79575" checksum="1A7AD3FE6AFB22D4" modified="2020-04-22" version="1">MQNGRRGVNIRTPRSRTTLGDRRNLPAGLGGGEFTPLLKNATMNSARRNNKENVQATPAFLRAGGMDKIQEGFSPLPAGSAYGDDSTRTGSYTAGTPMPHIDSSTASTPAALLPRRNEGPGVLQDGNQLSLREQENVIDRIEKENFGLKLKIHFLEEALRKAGPGFSEAALKENTELKVDKVTMQRELQKFRKTLTAAEKDRKHVNAGQQEELDNLRQVLEEKEDELNRVRSQEDKYADMENKIDDLEADLREKDRLINDREDDIDNLKDDVEKHVGAISDLEAALKKSQRRAIELEEKAQGRSNDELRGAESTIKELEREVERLRIEAEEAKEDHQEAIRDKERAEANLEELQDELANKSITTKGLSRQIEEKANRLQDELEDLRERHQNLEQEYADKTREAKKAQERLEDLKRDTEVKEQKLHDKLEQVENDLDQTIRERKALATRLESLQGLQRDFQQRNEEKSLLQSRHDALTAESAGLQADLAKAKTLIEELEDKLEHEKTLALGNERDVRNQYTEEIDRLSNEVEDLKAEIREKERLYDDDIENWETEKRNLETQRVRAEEQAAGLQKTIDRLQQTEGSLSGRESKLREAIRTEKERHESQEALLTRQINELNEDVQTRRKALEESRSELANVREELRLSQREQRSMAEKIEGLEDEVEILQTSLDEESDQANQDCKSRTRSIPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW55</accession>
    <name>A0A5N6JW55_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase C14 caspase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_007518</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW55"/>
    <dbReference type="OrthoDB" id="3223806at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="6">
        <location>
            <begin position="125"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8293172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="419" mass="46002" checksum="8423F9E38F36DC93" modified="2020-04-22" version="1">MSGYPGYNNGGYGPPPQQYPPQPYYPPQQPYGAPPPQGGYGYHQPPPPQQPYGYSQPPPQQYGGYNGVPQNAPPQYGRQGMPSVNSNAYTNGNQNAPPPPPQGMHSFGQGAPQGYAFQYSNCTGKRKALLIGINYFGQRGQLRGCINDVKNMSSYLHENFGYQRDDMVILTDDQQNPMSQPTKQNILRAMHWLVKDARPNDSLFFHYSGHGGQTKDLDGDEEDGYDEVIYPVDFRQVGHIVDDEMHRIMVQPLQPGVRLTAIFDSCHSGTALDLPYVYSTQGVLKEPNLAKEAGQGLLGVISSYSQGDMSGVASNLMGFFKKATTGDDAYNKTLATKTSPADVIMWSGSKDDQTSADATIAAQATGAMSWAFITAMKKNPQQSYVQLLNSIRDELATKYTQKPQLSCSHPLNTNLLFVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW57</accession>
    <name>A0A5N6JW57_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase C14 caspase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_007518</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW57"/>
    <dbReference type="OrthoDB" id="3223806at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="6">
        <location>
            <begin position="117"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8293171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="411" mass="44996" checksum="9DBF0A21E49497F7" modified="2020-04-22" version="1">MSGYPGYNNGGYGPPPQQPQQPYGAPPPQGGYGYHQPPPPQQPYGYSQPPPQQYGGYNGVPQNAPPQYGRQGMPSVNSNAYTNGNQNAPPPPPQGMHSFGQGAPQGYAFQYSNCTGKRKALLIGINYFGQRGQLRGCINDVKNMSSYLHENFGYQRDDMVILTDDQQNPMSQPTKQNILRAMHWLVKDARPNDSLFFHYSGHGGQTKDLDGDEEDGYDEVIYPVDFRQVGHIVDDEMHRIMVQPLQPGVRLTAIFDSCHSGTALDLPYVYSTQGVLKEPNLAKEAGQGLLGVISSYSQGDMSGVASNLMGFFKKATTGDDAYNKTLATKTSPADVIMWSGSKDDQTSADATIAAQATGAMSWAFITAMKKNPQQSYVQLLNSIRDELATKYTQKPQLSCSHPLNTNLLFVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JW59</accession>
    <name>A0A5N6JW59_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nrap protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_007525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000012">
        <property type="protein sequence ID" value="KAB8293180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JW59"/>
    <dbReference type="OrthoDB" id="10251401at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035371">
        <property type="entry name" value="Nrap_D6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17407">
        <property type="entry name" value="Nrap_D6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nrap protein" evidence="1">
        <location>
            <begin position="2"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="89" mass="9889" checksum="7E186AC41F5D1F05" modified="2020-04-22" version="1">MFNEELECLFNGSIVFFRSATDISRIGGLWNPQTAISRTFKVNLSYAAKPVNEKGEDSEEAKNVEINKSAILAEIARLGGDMVSRIEIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXV6</accession>
    <name>A0A5N6JXV6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009437</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXV6"/>
    <dbReference type="OrthoDB" id="5325318at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8293968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="180" mass="21326" checksum="EDA6215632696FCB" modified="2020-04-22" version="1">MAITTTTATDRKKRVFRFKKPLTLPKLLSLFYLSYPLLFHLEDQDSRHSHPNSISTALFYRFRSVFIHDISIDQYLKGKPRAGFPGYTTFKNSTNLHHTHLLYSLNIEDCLFLKVLFQFSNLNLNKRSNFQLFPYSSCSIYNNFINFNFPTSHLKDETNHIHSLFNRTLSYQDQFRLLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXV8</accession>
    <name>A0A5N6JXV8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXV8"/>
    <dbReference type="OrthoDB" id="10291784at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="219" mass="25184" checksum="09AE3F8545294C46" modified="2020-04-22" version="1">MRMFQEQEGSRPISPPRSRSSSLAGCREPPQDANNDPVCLPELYDTRHVEGAAGFKYCTKDESFVSLEWLERVDQISKIEGGKIFLEWIPHGTDMDKRRTFETRFTVLEELPCDFLMGRKNEDRDFNRKTPFSSSPPPPSIFNHYHSHSDSPSRLCQRQNAKLILQSHLRPRLQLEETEPSILLQDKPQPPRRTSHSESSSSQRSRGANGMIGYRAIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXW2</accession>
    <name>A0A5N6JXW2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_009458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8293993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXW2"/>
    <dbReference type="OrthoDB" id="5419922at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8293993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="515" mass="56413" checksum="E07092133E8FFC52" modified="2020-04-22" version="1">MSFKSEKIEEITVLQVKHESDIDTQIQADREALDIIEDAEEVSGVAQGKTEEEVQEAMRAEPETDDVPNSALSSGHTSTSSSPARTNNLTIHNLTSIQKARNVDRISRSSLLNQFTPLMPSEGDIISPASTQDLTEQSLKAAASDENTAIPSGDTASSKGSNSESQSKEPTVSQNNCPQSPWAPGEALPLVAHRKLAATEMIEPHSDVESPHPGWQKEERPVTPDNDFIRPFRDLMTPSPPPEALDTLGIEQRPSHTQLLIEAATQNPWVNGPKKKSTKRKRVSFGVLDDEDPVQSQPSSRRKRRSPSPQSLYRTGACGSKVAAFDDDVTDINSFQNHFSAIRKNSKGDGVAKRNSVERPLSSPKFKTILLGAADPIVSSPAIDAMAEAFIAADRESSRERDRRFTTSPLRNRMPKNQEHTTFRDEDEDNPGIQPFSSHSSAMAALNETSSNAKVGDHAAGDFLDEVEGFLGGDWSVEGELKKANSTEFDMFTSKGERNAQSRRSLLTLEENVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JXX5</accession>
    <name>A0A5N6JXX5_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JXX5"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8294001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="68" mass="8021" checksum="B5169085503FD021" modified="2020-04-22" version="1">MKGLQMQKLPTKPPFRYRSRKLRSFGAWDARNTPRLRSDIAASKIVEKKNYKIVAKETQFKEIIGKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JY90</accession>
    <name>A0A5N6JY90_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009513</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JY90"/>
    <dbReference type="OrthoDB" id="3539582at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8294057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="260" mass="30714" checksum="FD8219337F391D71" modified="2020-04-22" version="1">MAKAVWFRWCVISRQAYLDIRPPHLYNEDGPELRKYMDLLSKIMDQMEYEIFHRVRQITSSIVLANVKSEEFKRRCRSEIGMISLAIFFFKVVTDEQLYYIYEPIWSSVDFSFIPGSDEKPPHNCSMVRKVKWDLRMFTKLGFGVLASHYFSNCLQRTAGRQDGLREIPRAEMRIVSVPRELSMDLRKTEEQSEFTERANDNNAENEDLFADGEALNHEENLFGEYPEVEVGDRDPYVSRDDEAREKERHAIGMEKMLHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JY92</accession>
    <name>A0A5N6JY92_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_009575</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JY92"/>
    <dbReference type="OrthoDB" id="1939479at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016929">
        <property type="term" value="F:deSUMOylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606:SF141">
        <property type="entry name" value="GH15225P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606">
        <property type="entry name" value="SENTRIN/SUMO-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="7">
        <location>
            <begin position="321"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="92"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="248"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8294129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="538" mass="61139" checksum="065EC78B554A5704" modified="2020-04-22" version="1">MGIYMRQFRSYEYDNGMKGMKGTEVSLLLHFKRKASQELSRNSIEVIESIQGEEMFETIKDWFWGTLEWFRRRGDLSYTDMSYSNIDAADEHTQRAEARENGSSAIKRQRNQLKNSAHRRTPSQPQKSTSTSMDQTESLSEEELRARADAQWIPPAFGAPAKFVEKEVIVISDDEDEDGQGKQKSIADCLRSPRSPKTPPIRLQPMKLERRISTIQDGSSLPERLANLLTIDDDNADETKRSPFTLSKRAQEKIKRNAEARKLKEKEEKIRIAKERRLTRRDPSNRLVHPLEVKWEDIITEALDRAQKNGNLPITESQGGTPLHYKDFGTLLGRSSWLNDEIINTYIEWVVEAANEFAKAEAKAVGEPVGKVPKFIAHNSFFYENLDKKGPSSTQRLMNRKKAPGASLLQVDTVFVPICRGSHWTVGVVRPMARTIEYFDSLQGSSHGFIKLMRGWLKFQLGPDYREDEWKTPNTGCTIQMNGFDCGVFVCTNALCVALGVNTDCYSGSDMAMMRRNIAALLINKGFQGDFAWGLGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JY94</accession>
    <name>A0A5N6JY94_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS19m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_009560</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JY94"/>
    <dbReference type="OrthoDB" id="2043at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.860.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_uS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF8">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8294108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="93" mass="10509" checksum="D7CC5157724FA977" modified="2020-04-22" version="1">MFPSRALLARSVWKGPNIVPLPIYKPVPGARPQPIRTQARSATILPNFVGLTFEIHNGKVYNEVTITEDMVGHKLGEFSATRKRFTYKQSKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6JY96</accession>
    <name>A0A5N6JY96_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_009569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000011">
        <property type="protein sequence ID" value="KAB8294121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6JY96"/>
    <dbReference type="OrthoDB" id="2922289at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788:SF2">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8294121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="566" mass="65265" checksum="AF8AE2D3626FC48E" modified="2020-04-22" version="1">MNDSKPEESSYLDIHEEYLHLKAVSDKKLQDFARKPDDKKKLIDVSVEAKERAGAVLRKIHSAVVLSKLDVLDSNFRMLLSDSESYGRIVVRNDDPDNREGYKEDGKVFFGGAYNISEGLGIMEAQQGLLEFLICYCREALSSMTRSAHSDITTPEFNPQVHLVEPSWPEIGMDRTFSNFYGAPQMQMPTDFSKLRSMFNVRHTLAMDHVWLLRINPGYFEKNIEGVLHQNDPQSRDVVRVIFKAFLALQKWECLRNLAAEAERLQKEYEKTPRDYLQAVVGPPKHYFVAVLKLFKVLTDFEDEAFDILKCGEDESEMTRQFCKCLGDTLKSDKVEINGIKHMGIMRALNNIMRKNRPMHVFDFMDDLEEVSIYESSDGKRISVKGRIFSAFLAHFLSDLGLLGIATYEVWKDWAAQIFAATKDQKDMNFEKSWQMEETAVAIDSILFMFKDRLRELGSLADNKFNYPIDAKRSEESTESLRKAEQALDEFWQYVDKIMLNNGFSEFLKVSSMNMAFWRTPKWQAPKITTHESRVTMPARVVSANNLSATPPEIFANDTQYVILHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K1F9</accession>
    <name>A0A5N6K1F9_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_008812</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000009">
        <property type="protein sequence ID" value="KAB8295996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K1F9"/>
    <dbReference type="OrthoDB" id="196650at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF31">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025008723" description="Major facilitator superfamily (MFS) profile domain-containing protein" evidence="7">
        <location>
            <begin position="20"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8295996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="31857" checksum="DB4E450D74A1A022" modified="2020-04-22" version="1">MALVGICFSISFTFGPALGAWLSTISTVQANPFATAAGFSLFLIVAETLYLYFCLPETLPSKVAQAKLNGEPAATNGVTKATGSSAKKTQAKIVSSSTDGLKKQGRTNSHFLLNLTHLSFILFFSGMEFSLPFMTYDLFGYTSALNGRLLGYMGLVASILQGGVTRRLPPLLSVRIGVVSCLGALFLLARINTVSGLYLATTLLAITTATVVTGLNALSSFEAGEDERGGKLGNLRSWGQLGRGLGPLLFTSVYWWAGREVAYSIGGLGLMGVSLLVTFGLKTPGGKQGKKIGDVKTEVEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3J8</accession>
    <name>A0A5N6K3J8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_002360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAP domain-containing ribonucleoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3J8"/>
    <dbReference type="OrthoDB" id="445357at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052240">
        <property type="entry name" value="SAP_domain_ribonucleoprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040746">
        <property type="entry name" value="THO1_MOS11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46551">
        <property type="entry name" value="SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46551:SF1">
        <property type="entry name" value="SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18592">
        <property type="entry name" value="Tho1_MOS11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="4">
        <location>
            <begin position="4"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="32"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="231"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00046328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8296952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="252" mass="27123" checksum="A478A13942979D0B" modified="2020-04-22" version="1">MTDYSQLKVPELKKLLQEKSLPISGNKADLIARLQESERKPAAEATASTGEDEIDWDEDDEKKDEKKATAPVDTAIAAAGGKEEIPNPTKITGGEGAPTAEDGAVAASGPTKTEVAPVPEAPKQDFSAGIEKSDAQKEAEKRAARAKRFNIPENEEAAKLAERAKKFGLDNSKIVEGLDSALPEGRQKRAREDNRQGGRNAKRQTPDNRRPQSGQKNTQKPGPRKPAGGRVTDDPVEKAKAEARAKRFAPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3L3</accession>
    <name>A0A5N6K3L3_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3L3"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="89" mass="10218" checksum="23E138BAA521BF05" modified="2020-04-22" version="1">MPYRSCKSTYAFLSCLINNTGLGNSRRYKWEKKVQGPVIPVRHFTLSLAFPKYIFLAPSLVFIIASTHQSIFDYPQRSGRSRVVVFTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K3L4</accession>
    <name>A0A5N6K3L4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_002362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000008">
        <property type="protein sequence ID" value="KAB8296955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K3L4"/>
    <dbReference type="OrthoDB" id="3902588at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8296955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="509" mass="56721" checksum="19084F5DDFF5A88C" modified="2020-04-22" version="1">MFDVSWTDPTRETVGQRKHRKDQTCTRGSSPSIRSSKSSDSSKSIKHSIFGFFGTNKKISVPVAATSPTSPKSPPLRTEQSSKGSRRMSSYTSTSETSTQEVRETTTTTITRIPVNGFFSTVPPYQESDRSPSDESIFSGYTGRSAGTQSSWSSMADGRNKNRFIQPLSPNSFVTQSTEITVAPSEDFSASEQLATVVHITSGTIPIQIQDSTMRESTLSSPSSTYEFPLPPTNNPETPKVPSSPKIPSSPKVLSSRSDIGARTTEWSITARNRRSDSWRPPETWACPAEETASSVASLKSSGSRRRRKIRGRNRSSSNSDQTHLQMNIRKMEAASNKIILERLKEEWMQVADASVYRELELEKQLWMLTALRAINRVARARDASQAINGAPEFGKMLSLYENHVNLEKQFRCLNPTRLFPLWLADAGLWAEGSCTSSLKFLACVGVVNGEEQVEWQLKSVMGRMLWKEMWGSYVEGDKWWWDDAAIVEECERMGTCWAGSIIEAVKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5P1</accession>
    <name>A0A5N6K5P1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5P1"/>
    <dbReference type="OrthoDB" id="3543450at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="682" mass="76381" checksum="B20A234CB5317003" modified="2020-04-22" version="1">MEQRDMPASNLREPAPSPVPTGMDTAQLEQVLDRTPQMTRFNLSSRRLHSLRTPDCRALKGGVTNGISCGRDKVATTPNSSPTAQSPHSSIGEDLKDGLRETTVVVEFDGFQGDLMSIDTIREPSDEEISRPKQSAGTLPTRFLKTIAKRKKLRREKREQCTSHPSKGTSSTCTLGGKADEPATPFPLGCGDQSEIGTPVTRPNISSDETSDDSEESASLEQLIRTARRTSNSQASNDSRAREISFSFGPLHPVRKAGIKSNDEDSDKGGKSCNINIAILGLTDKNDSSQPTNESEEASVKNNIQRDHQTSQGNKKKKKRPRRLPVNELYMVSERVDEMTQEEEYEDVQPSAELADDPISQYTSDALQVIETAGQTKCERRKPQTCNYGAFGKIDNRVYRFPALHNTFLQEVDSRHEVTPSYSDGFEGSEAKPTGRFMLVPKQKRVSVSMWGLKTRVRQLELVSRKYDELIDQPNCQAKIEVPARKFMRPLNKKAVSSAIVLVEAASQAIETDQAQQIDRDNQNPREHQKDKNPADVKRIPLSPQNMIVPRTVTFDERVKIDRPLSISLNSREFKEYPKGKERHTSSDFQVHREVATVRLKRYHHEFDSEEEETSVNESQQSVVSILSDDDESEQSDETCDDSDEEMHTGTEDEDKNGKDCDVPAALQRPADDQADETETNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5P2</accession>
    <name>A0A5N6K5P2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5P2"/>
    <dbReference type="OrthoDB" id="4152802at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8297908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="366" mass="40488" checksum="FB60DB051C7DDF37" modified="2020-04-22" version="1">MNLDQSRTPSPAKKQRVETEPAKQPVEAKISQSWKSFFRRNKRLSRASTPSFSNTSRETVQTGPPPHLGHAPMVRQTSNIPKRTMSKFREDLPELPISPPDSRVQSPENDVVPPIRTDYLDKRASVRRSLEEQRRHDTPMSVMRLRDSTPTSAHRSTDVPSPEPPTILSQSLASIDSEGSWLSGKKTNSKRGSAQMTLAPLRDSASSLHQRYKELSESSEELGIAEDEYFSRITPGPEESMMKRQSTGLPMASSDEEDGGSIKQSPIYEEKTTWGAVARHPTVVHRERANSRSGLLDEAAEGSAGYRRSISYQAELVNEDSPGISRATSVDFGHVRKVSAGSARLLDMKPRASGEGTRMSVSHGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K5P4</accession>
    <name>A0A5N6K5P4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_001629</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8297832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K5P4"/>
    <dbReference type="OrthoDB" id="15433at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="366"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="185"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="611"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="611"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8297832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="640" mass="72371" checksum="254F8704629CFA50" modified="2020-04-22" version="1">MERREFIQGKIEKQQRWRAKSIEALIGLVEPKETPLLNKTTANHEPVGSLIWSPYTTQEDPKRLTKEEEESILLHLKQKVQGVARFAAKEAAKKAFSKRRLGFHDITIDNPSLDNLKSRAPITLIKSTKGQEDQIVPMSISHDGDYATAVCISCEDFTPPPMPDLQEIEPVLGRLLDEMTLKRLSRNASQTPLRDSTKEDFPPELPPERLSTPLQAVPVKMMTPLTGRLSEILNATPGGGSSTSAMGIKSSLNASEASEPVQPTPINDSTIESNLDVARAPDAVHPEVSPSSPNSPNIKYHLSASSAVRSINVDLLNKSFNRNSPGFQPRGYSFDDSQAKGNPPTDFQVKYYPIAGAPSSDVPVLQPGDWVCQSEGCGFQNHSEQRRCVNCDTKRFEGWANYIDPDSTYNKQLAEYANYTGLPFEIDPEKEKEKKARIEVRQERLKTRTQSIYGLPTYIDPKVVKKNVENCLAVDNLPPGTTNEELIEAFKGRCTAIKGYVKVSRVGQIRAWVILSRKTEANKLRHLAKKPHLLPVIRGHHLKMTETDDWIRNLLREYANGCRRWDWRADFWTTNVFHAYNREECEQHAQRQAKEREAIIAEEERLRIAAEERKTAKEKKREVKKKKKMAMKELSSSSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K611</accession>
    <name>A0A5N6K611_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_001775</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000007">
        <property type="protein sequence ID" value="KAB8298003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K611"/>
    <dbReference type="OrthoDB" id="2094445at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021278">
        <property type="entry name" value="ATP19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28074">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT K, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28074:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT K, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11022">
        <property type="entry name" value="ATP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8298003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="124" mass="13886" checksum="08D7421CDB90B914" modified="2020-04-22" version="1">MAALIQLNCINTITNLHLVTANLFEQLSIYLHRRTRQNGFLLSNRWKASWLPLRRWPFETSKSPLVQILRFLLQSNCTTHALAIAVLGSLAGVVTLSTRGGSTAKNQSTPPINAKSPDEEKYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7S7</accession>
    <name>A0A5N6K7S7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PRISE-like Rossmann-fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000986</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7S7"/>
    <dbReference type="OrthoDB" id="1731983at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08948">
        <property type="entry name" value="5beta-POR_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055222">
        <property type="entry name" value="PRISE-like_Rossmann-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487">
        <property type="entry name" value="3-OXO-DELTA(4,5)-STEROID 5-BETA-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487:SF0">
        <property type="entry name" value="3-OXO-DELTA(4,5)-STEROID 5-BETA-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22917">
        <property type="entry name" value="PRISE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRISE-like Rossmann-fold" evidence="2">
        <location>
            <begin position="38"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8298817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="408" mass="46142" checksum="D56AA1A3E82AD4FD" modified="2020-04-22" version="1">MPLTIPIQKQQPASKTQRKLRQNSANPAMASSGDPKVALVSGANGITGSAILKQLSKNPIWTRIIAISRSPPKNLPSDPRIEFHSLDLTVSVDEIAGALTSKGVTNVTHFFHYAYIHTDYDHPRHLEKMTEDNVPMFTKTLTAVDLTSRDTLHRVVLQTGGKNYGLMLVPPASVPMTEDAHRVTDPCSLPNFYYHQEDFLWSLSKERTWNWNITIPFWISGYVGKSGNSWTTSAAVYFSLLKALGRPAVFPGGEDEYYGKWEKGQHFSTNWVIADFTEWLALNEDPAVQNQKFNIVDDTVTTFRDVFEGIGKYFGVETKVERKYDLMSEAKELEKQWPEIVQKYGGKEDALGLCTWDAFVYAMSAGEWGSVVNMDKARKAGWTKRVDTLKEMEKIFEDMKRDGWIPDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7T2</accession>
    <name>A0A5N6K7T2_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_001002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7T2"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8298838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="76" mass="8688" checksum="468C4A853F182477" modified="2020-04-22" version="1">MSKDLTPVQEAKKIKDMEFRQREIEDSKALTAQAEQRCAEIMADFIEATVEERHAYEQGKMEGQIASYTSNFLGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7T6</accession>
    <name>A0A5N6K7T6_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000993</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7T6"/>
    <dbReference type="OrthoDB" id="428895at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035426">
        <property type="entry name" value="Gemin2/Brr1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04938">
        <property type="entry name" value="SIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024928654" evidence="2">
        <location>
            <begin position="20"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8298827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="310" mass="33600" checksum="E6B6481F7537F0AD" modified="2020-04-22" version="1">MNKDTVLKLLKLLMGGTLLQSGSDINVKVSRWAWALLARLPVRGELSSDEIGVVRELGKKAALLGVGLKAGGGLKSGLNEVEKVFEADNDVEIVDDEKVPSSGDENLVDGSGNSRELEDQAQPENKDAPQVFNLVENSMLSVTTETLTAPEEVLGVTPDSHELDAIKARLLANITPDRPAVDATATEGPQASQAEKPTPSKTETPVYTPAQTIDWNTRATIDMILTIAGEIYGQRDLLEFREVWVGLKNPGAQSLRYLLALAQGACLIPPICCRPRHRNQQTPQIYAINIDNPEPLIPIVQFPLPITCNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K7T7</accession>
    <name>A0A5N6K7T7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">REJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_000957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K7T7"/>
    <dbReference type="OrthoDB" id="10632470at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5024962012" description="REJ domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8298783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="463" mass="48993" checksum="A3449D809AC9BBA4" modified="2020-04-22" version="1">MDVTSFMLLFFLVPASIFSVFAQVELPPNSSSIQGRAIPVITLTTNTILIVKVTAVFTETDVIIASPVVVVAFTKLSTSIDAAIASHIALVSSQSTESLPSSIAPSAPVDRTGTAHLTLITSDRAQTSSSSSSDPSILSDTTYTIDTTSITPGHDESYPSSSRIHLSTAHGSSQLNIFSYTQGSSSRFSTNLPTTTPIIVETTSISSSSTQILPTTSLSYDLDSTTVKWITKSASLSPSTTTTTITYPQDGFGFYPSEIAENWNGNMAAHAIQSSTSGHTLQTSEISIIRTILEISTATVPTATVYVIASSSQNTSSTSNSKSLLDTARLSSSGFSSESSTIVTAKLIPASTFANNSVVPPSLTMSAQPLLSSSRLEISNSSATTTTSKLPYLNTTYLLSHFEQSLPASSLIRSSNNSSFLISHTTPIPPLLETKTSTDQTDTSILFDSGDQHYADILLFFHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K836</accession>
    <name>A0A5N6K836_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">EYC80_001108</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K836"/>
    <dbReference type="OrthoDB" id="421009at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15844">
        <property type="entry name" value="SNARE_syntaxin5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF3">
        <property type="entry name" value="SYNTAXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="246"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="85"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="151"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAB8298962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="338" mass="37281" checksum="92DE23F275CA7FDA" modified="2020-04-22" version="1">MHTIPQYLLISSSYISLIHNKHTPASTFRLTQQQSEPPSIKETGSSEAITSLRFTKGRSKWRCKRTWTTQKIGICEKGRRDWERDNRHHGEVTKAGRIGQTQNPLRRPPGGNQRTHLHHQTRPLLPQPTNLGSPKPHASPAPQSRPGGANTTKTSSSCSKASSPTSPPTSKTCSKSAPRTSRPRAPAPKIFVSSVSSHVQPNISQSASPLYSTPARGSPGPGQDLLSLNPVGDQQLLMMEEAQPQNEYIHQRGEAIEAIERTISELGGIFGQLATMVSEQSEMIQRIDANTEDVVDNVEGAQRELLKYWSSVSGNRWLIAKMFGVLMIFFLLWVLIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6K856</accession>
    <name>A0A5N6K856_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_001097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000006">
        <property type="protein sequence ID" value="KAB8298947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6K856"/>
    <dbReference type="OrthoDB" id="10251048at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8298947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="184" mass="21149" checksum="4A439C304DD9C1EF" modified="2020-04-22" version="1">MQEALQYYPHGFPSDMNGRYTRLSVEVQKEMGLLADEETPEQARARKQKEKDEWFYGGQKRWNMTTEDHIKEIEVHTNPFGNIGPPRKVLPSDSRPLPGITISEMKKKTMPEVIAPMLDGTFGNMFAIEAQQKDSNPVSPFNRYTKSPEWHIDSSEKGNDSFFGEDWGVPTHVPTTQSARIQRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBH1</accession>
    <name>A0A5N6KBH1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_000672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBH1"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8300508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="110" mass="12156" checksum="9540CB8FF873244A" modified="2020-04-22" version="1">MNHKKLLPEEAGTSGSISRQRNRLSGYIDGPDNHVTLSSLSGRDLFIKFAFVSGLSQAHSPIKIFALELIAQKSLNAYIHYSGCVMTFCIHKSRLCDRNAANRPSIHNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBH8</accession>
    <name>A0A5N6KBH8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_000649</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBH8"/>
    <dbReference type="OrthoDB" id="5330858at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8300481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="342" mass="37363" checksum="A9C54DBF505EF6D6" modified="2020-04-22" version="1">MTIINIESALRQAIRTSQSGPIRAGELVNAIVKLDREMELLLQLVSSNLLGAAELLHAIRKLMETMDLFEVGESPNSKQALLTNGEYVNLENGNVEEEVQRLEAEAEDDLQLAEFQLGEGSGVRGEALNVALSKLYTCPDNSITDALQTTFTSQETVSLIYILRVELAKGGWTGRYLDIMELDDDEVEAPDNSIILISSLLNNCIDALAAGGWLTGNARLINGDQSESEAFIGTLKMEISAALEGIETAVYLKGLTSEMVRYGNSVLKGIRHEDTGRMANSIMSLPSGEKDISILPIGLKAERQISLLRVGAGGEVQKRSKRDIGRLLSRQVAKYTRERIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBI0</accession>
    <name>A0A5N6KBI0_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">EYC80_000642</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBI0"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF201">
        <property type="entry name" value="MFS AFLATOXIN EFFLUX PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="56"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="541"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="603"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="541"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="605"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="615"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="630"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAB8300472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="647" mass="70396" checksum="9409AC066418400D" modified="2020-04-22" version="1">MVGPAVELDSAQTTTTSSFGAPLSTSSNRDGRITRWDTRDNGVEGRYPSWKKLSVVMLSLYLCILIVSLDRTILGTAIPTITNEFHSLEDVGWYASAYLISSSATQLLFGKTYKFYNYKWVLMIAIAIFEVGSAICGSAPNSKVFIFGRAIVNGVILIMTDNVPLHRRPLFMGLFGGIFAISNVCGPLIGGVFTTKVNWRWCFYINLPVGGAVALILFFIVKGSPSKNKDTLHQKVQKMDPLGTIVFIPGIICILLALQWGGHTYSWRNARIIVLFILGGILLIMFVIIQFKSGESATVPIRVIKQRSIASAVWLSFFSSGSMFVLIYYLPIWFQASRGLNAINSGLHTLPLVLALVLGSLFAGIFTKATGYYVPMVIASPIILTIGAGLLTTLRKDSGPREWMSWQVIFGWGLGLGIQQPNLTVQACLPDDDISTGIALMFFAQGLGGTIFVTVGQIIFSYELVKGISALNIHSLPASLILHTGATEIRNIVPQFYIEKVLIVYNDVLTKTFRVAIFTSALTILASLTLEWKNINKANRNPQATNLSTSHTGSGTNEESSGVVRTAEGLDTAQGGLGQLTDHKNADSEPAQAKLTILQQQQLETIREEREKSSSAETSPNATTTSDGTEVDKVVVSEKDGEIKIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KBI2</accession>
    <name>A0A5N6KBI2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cyclophilin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Cyclosporin A-binding protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Rotamase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_000680</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000005">
        <property type="protein sequence ID" value="KAB8300518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KBI2"/>
    <dbReference type="OrthoDB" id="410198at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000013">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="11">
        <location>
            <begin position="6"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="10">
        <location>
            <begin position="327"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00081826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8300518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="517" mass="58019" checksum="7D4456E74ECD0731" modified="2020-04-22" version="1">MTLQLSEIKDVTEFAELVKVEHRAYATPANSLWEVLKGSSIKECTERQWAWHTGTPNSHWLQVKEGDKVISGAEWIIHETNPFSEPQPTVKGTWWPEGPLKTISDHILELFFEGRPSVMNRPHLLINYFFVDPEHRRRGAGNLMMEWGCKIADKMGLETFVESTDDGRELYKAHGFVIVRHFFLYVPSAPKVDEEEFAKLKEVIAPEPYRVWLMWRPNGGKFEEGKTIKISSPTMFSANSAFQWIHTDAKPKYMAPPFHAPFQKYAYPSPAASLEVNNSSLYNILAPSFFSITSSFPFFQSSTSTPASASTTEATIKSSDNSSKNCFFDITVDSAPAGRITFKLHDDITPRTARNFRELCTGQHGFGYAGSPFHRIIPQFMLQGGDFTRGNGTGGKSIYGNKFQDENFVLKHTKPGLLSMANAGRNTNGSQFFITTIATPWLDGKHVVFGEVVEGMDLVKKIEGLGTRSGTPRARVAIAKSGVVDWIAWKCGVCNLVTIFIFRLRLNNSMEYSTTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDL2</accession>
    <name>A0A5N6KDL2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thiazole biosynthetic enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_003334</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDL2"/>
    <dbReference type="OrthoDB" id="410463at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43422">
        <property type="entry name" value="THIAMINE THIAZOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43422:SF3">
        <property type="entry name" value="THIAMINE THIAZOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01946">
        <property type="entry name" value="Thi4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8301474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="18563" checksum="D1BCAE78CFA836B5" modified="2020-04-22" version="1">MAPPSAMFPEATSPIDGVQLKTGFDVKVAPAQAATQGKTLADLAEKWDQGFTFAPIRESQVSRAMTRRYFNDLDTYAESDIVIVGAGSCGLSTAYMLGKARPDLKIAVIEASVSPGGGAWLGGQLFSAMVMRKPADAFLTDLGVPFEDEGDFVVVKHAVCLIPIHCPTDFYNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDL6</accession>
    <name>A0A5N6KDL6_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein uL15/eL18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_003004</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDL6"/>
    <dbReference type="OrthoDB" id="6353017at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000039">
        <property type="entry name" value="Ribosomal_eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021132">
        <property type="entry name" value="Ribosomal_eL18/eL18-A/B/_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17135">
        <property type="entry name" value="Ribosomal_L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01106">
        <property type="entry name" value="RIBOSOMAL_L18E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="5">
        <location>
            <begin position="76"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="226"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="234"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8301092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="257" mass="29372" checksum="B84634C4D6F8725A" modified="2020-04-22" version="1">MLNWLLYHFRKVIALPLPLLLGTWGGSIRYPPKILSELTHLLHILNFFQNCFSSRWNLSTTSRHLDDKPPKSPTMGIDLDNHHVRNTHRKTPKSDNVYLKLLVKLYRFLARRTESSFNKVVLRRLFMSRINRPPVSISRIAAQTDKEEKRTVVVIGTVTDDNRLLTVPKVSVAALRFTATARARILAAGGEVLTLDQLALRAPTGSNTVLLRGPKNSREAVKHFGFGPHKHKKPYVESKGRKFEKARGRRRSRGFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDM0</accession>
    <name>A0A5N6KDM0_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDM0"/>
    <dbReference type="OrthoDB" id="635774at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="179" mass="19781" checksum="D757412A13864A16" modified="2020-04-22" version="1">MGRGSLSEAHDDIPERGRSRSKPHSPLFMASRSPEKTITNLRTNGIRPSQIPLPRSVSSSDYSKDQIDQQQSHNQNTSTIENSTLETRQQDSEFPSYSEKDATDIQSNSTTEHARNTVAAPNISMAYAEDFAHIGTGVDSAHRGSFPFAPVDIDDDDLTIDNEASNVLYWKAEEKISLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDM3</accession>
    <name>A0A5N6KDM3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="19">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">EYC80_003367</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">NADH-dependent reductase for DPH3 and cytochrome b5. Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1. By reducing DPH3, also involved in the formation of the tRNA wobble base modification mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), mediated by the elongator complex. The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>2 Fe(3+)-[Dph3] + NADH = 2 Fe(2+)-[Dph3] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:71231"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="Rhea" id="RHEA-COMP:18003"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:71232"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 19">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18 19">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Monomer. Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 19">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="19"/>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDM3"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000032">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000019">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF184">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 18 19" id="KW-0274">FAD</keyword>
    <keyword evidence="5 18 19" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="11 19" id="KW-0520">NAD</keyword>
    <keyword evidence="10 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="20">
        <location>
            <begin position="64"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00037104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00038836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAB8301516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="313" mass="34255" checksum="6469B673C80729D8" modified="2020-04-22" version="1">MSTVPTNKFLSKTYIDGIYIPSGLLILGCFIVKKEWIPFAVALAALLGGYKIWASQETPVLKPTVFQDFELKEKTIISHNVAIYRFSLPKPTSILGLPIGQHISISAVLPQPDGQSKEIVRSYTPVSGDHQPGYFDLLIKSYPTGNISKYMASLVVGQTIKVRGPKGAMVYTPNMVRHFGMIAGGTGITPMLQVIRAVIRGRATGDKTEIDLIFANVNPEDILLKEDLDGLAAEDKGFRVHYVLNNPPEKWDGGVGFVTPEMITKWLPKPADDVKLLLCGPPPMISAMKKASEGLGFKKAKPVSKLEDQVFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDM8</accession>
    <name>A0A5N6KDM8_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">EYC80_003011</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDM8"/>
    <dbReference type="OrthoDB" id="10266426at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015218">
        <property type="term" value="F:pyrimidine nucleotide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990519">
        <property type="term" value="P:pyrimidine nucleotide import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049562">
        <property type="entry name" value="SLC25A33/36-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829:SF1">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06780)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="10"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="121"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAB8301102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="33248" checksum="FF31177C4B20BF1A" modified="2020-04-22" version="1">MKAKKIFTDNTVLVNFWSSIIAGASSTMVTNPIWVIKTRLMSQVSRKAKNNGARPPWHYRSTLDAAKVMYRTEGFLSFYSGLTPALLGLTHVAVQFPAYEYLKTKFTGQGMGASAEGDESSHLFGVLSASVLSKIIASSTTYPHEVIRTRLQTQQRSMSAASTEYGAFRGGLEGHSQQQGVSNPLAQFKHAIPKYRGIVMTFKTILRDEGWRAFYAGMGTNMMRAVPAATTTMLTYEYIMQHLNHARAEGIRKSGEEWSYSSGVRGYDRDQETFLHFTALEVCGRLVMYSAIRYIELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KDM9</accession>
    <name>A0A5N6KDM9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_003349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000004">
        <property type="protein sequence ID" value="KAB8301494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KDM9"/>
    <dbReference type="OrthoDB" id="310217at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8301494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="546" mass="62372" checksum="D9F093BDE17D9BC5" modified="2020-04-22" version="1">MIHCTEWCEDGDEDKPYGIIPEVAWKDYKNRVGPPGRFVLKLYAVSNTWLGLTDEEGGVHTLATQDDINYYNGEYDDIPPGHYDYKDMPEAEKNMNKRRVEIENRARARFRDSRLYSDELHKLVMDCLIVQQESRIHVEELYRATKRFKELWAEKVGLQAPLPYFPEPTVKDAKLPPPWNDLNREQGGGLGRPVPEYLESHELGVDDLFHATTQYEKAAMVRLWARRNPIDNPSDDDIRQALGVIDRNARHFITYNTTTGQYRGQRNRPVYEIPEAFPGGDFIKYDRTDEDDGYYGGGRGYGGGGGDLGHPSPQQKLLGIANPDPDSDAIPDHLKNVQSTPEHMKARYSKDTPPELRGGVPKAAGDLGGGLGGFVRMEVEKERLDQELGDQLRSRSGSSLPHRGADQRRERKKAQAELEAREREREQDEEERLRNWPVFPTGLQKSIDEALITHALELPELQNSVLFCTVTERQLMKEMLTEKETGVPVEDMKLMGNDRLTVFREFEDEELRSVICGVEIFPLITPEGLSTNNMHIFLYSTISNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFP1</accession>
    <name>A0A5N6KFP1_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">T-complex protein 1 subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">EYC80_005895</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFP1"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAB8302495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="30843" checksum="FFDEBD49B02E649D" modified="2020-04-22" version="1">MKAKVDKIKAHGINCFINRQLIYNWPEQLFSDAGIMSIEHADFDGIERLALVTGGEITSTFDHPDQVKLGHCDLIEEVIIGEDTLIKFSGVAAGQACTIVLRGATEQLLDEAERSLHDALAVLSQTVKEPRTTLGGGCAEMLMAKAVEGAAVKVDGKKQIAVGSFAVALRQLPTILADNAGYDSSDLVARLRSAIYDGMSTYGLDLLTPGGGIADMRELGVIESYKLKKAVVSSASEAAEVTSPQSGQYHSQCPTETRKMSVMKEEKNDDCIMKMQTCSRGFVATIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFP3</accession>
    <name>A0A5N6KFP3_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_005828</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFP3"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="187" mass="21223" checksum="41E6680914DDDF47" modified="2020-04-22" version="1">MKALHDVVESGKVRYIGASSMWAHQLLEMQYTARMNGWTEFISMQNLHNAAYREEEREMVPSLRKFGMGMIPWSPVMMGYLARPHDEATESDRGKAMNGKFMGNALTEADIRINEKIQEIAEKRGVSMAVVAIAWSLSKEYVTAPIVGMGKIERVEEAVEAVNFELTKEEETSIDELYQPRKIIGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFP4</accession>
    <name>A0A5N6KFP4_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylthioribulose-1-phosphate dehydratase</fullName>
            <shortName evidence="7">MTRu-1-P dehydratase</shortName>
            <ecNumber evidence="7">4.2.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MDE1</name>
        <name evidence="9" type="ORF">EYC80_005968</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mlax316</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-(methylsulfanyl)-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:15549"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="4.2.1.109"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the aldolase class II family. MtnB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.109" evidence="7"/>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFP4"/>
    <dbReference type="OrthoDB" id="191080at2759"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046570">
        <property type="term" value="F:methylthioribulose 1-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000003">
        <property type="entry name" value="Methylthioribulose-1-phosphate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03116">
        <property type="entry name" value="Salvage_MtnB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017714">
        <property type="entry name" value="MethylthioRu-1-P_deHdtase_MtnB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027514">
        <property type="entry name" value="Salvage_MtnB_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03328">
        <property type="entry name" value="salvage_mtnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640">
        <property type="entry name" value="METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640:SF7">
        <property type="entry name" value="METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="8">
        <location>
            <begin position="30"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAB8302590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="252" mass="28666" checksum="6CA2B38FDE3A78FE" modified="2020-04-22" version="1">MTTQNPNQDVQNSEDNHHLIISQDPQHPANLIPELCSKFWHLGWVTGTGGGASIRQDDLVYLAPSGVQKELMKPEHIYVLDISKQVDPKQRIYLRSPPNLKPSQCTPLFMAAFTKRKAGCCIHTHSQWAVLITLLLESTPHTTMFEINNIEQIKAFGKGYTKSGNLGYHDTLRIPIIENTPHEEDLTEYLEEAMEKYPDTYAVLVRRHGVYVWGETVHKAKTQCESLDYLFQIAVEMKKLGLPWLSDIKSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFQ7</accession>
    <name>A0A5N6KFQ7_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">EYC80_005896</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">Mlax316</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFQ7"/>
    <dbReference type="OrthoDB" id="63989at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990604">
        <property type="term" value="C:IRE1-TRAF2-ASK1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070059">
        <property type="term" value="P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036498">
        <property type="term" value="P:IRE1-mediated unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.180:FF:000002">
        <property type="entry name" value="Serine/threonine-protein kinase/endoribonuclease IRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.180">
        <property type="entry name" value="KEN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045133">
        <property type="entry name" value="IRE1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010513">
        <property type="entry name" value="KEN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038357">
        <property type="entry name" value="KEN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954">
        <property type="entry name" value="IRE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954:SF6">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06479">
        <property type="entry name" value="Ribonuc_2-5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51392">
        <property type="entry name" value="KEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6 15" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025032807" description="non-specific serine/threonine protein kinase" evidence="15">
        <location>
            <begin position="27"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="KEN" evidence="17">
        <location>
            <begin position="92"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAB8302498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="227" mass="26663" checksum="246EF90EC69DEF67" modified="2020-04-22" version="1">MPNRRATRAIDIFSLGLVFFYVLTKGSHPYDCGDRYMREVNIRKNNFNLDVLEILGDYAFEAKDLIGSMLGKEPKSRPTAAQVLAHPFFWSAKKRLNFLCDVSDHFEKEKRDPPSPPLLELERWAPDVCHGDFLKPLGKEFVDSMGKQRKYTGTRLLDLLRALRNKKNHYEDMPDKLKKDVGPLPDGYLSFWTRKFPNLLIICWNVVYELEWDHVDRFKEYYEPDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KFQ9</accession>
    <name>A0A5N6KFQ9_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_005970</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KFQ9"/>
    <dbReference type="OrthoDB" id="1732691at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004084">
        <property type="term" value="F:branched-chain-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF69">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8302593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="136" mass="15723" checksum="4A225B0A2F72FF3E" modified="2020-04-22" version="1">MLEIEEAQKEGRVVEAFLSGTAYFITPVSAISFRDRDISIPMQEDGGVYTKMIKTWLYDIMYGNVEHEWGVILIKVKSSIHLKSLVRLKYKVSPPDLHFTPLSMIRPQSTINQGYWWSVLKKDCKIYANVKLSIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KG12</accession>
    <name>A0A5N6KG12_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">14-3-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_005913</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the 14-3-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KG12"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11309">
        <property type="entry name" value="14-3-3_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000002">
        <property type="entry name" value="14-3-3 protein epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00797">
        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="4">
        <location>
            <begin position="150"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="378"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="379"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8302521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="414" mass="45941" checksum="83CE228723E2CBAB" modified="2020-04-22" version="1">MLLDLSTATIITSPGPGPGPGPSSGSGSGSGLSSRPSSRPNTSPSSSQSSITRKPEHQHFNKEMTKILPPQAKFKANDECGLPATSSRSTYAFSNRENHPKHPNPTHNTQHTQTQTHKQSQSLRRIPTYLFFPFQFVRFLSQSPTYSHTEDTQIYKSQSWAERYEEMVENMKSVASEDQELSVEERNLLSVAYKNVIGARRASWRIVTSIEQKEESKGNSSQVTLIKEYRQKIEAELAKICEDILEVLDKHLIPSAKSGESKVFYHKMKGDYHRYLAEFAIGDKRKESADKSLEAYKNATEVAQTDLAPTHPIRLGLALNFSVFYYEILNSPDQACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSSEAEPAAPEAAAAPAETKEAEAEAEAAAPAEDKPAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KG16</accession>
    <name>A0A5N6KG16_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">EYC80_006071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KG16"/>
    <dbReference type="OrthoDB" id="5294180at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF12">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAB8302713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="336" mass="37343" checksum="764C302ACDCDA3E2" modified="2020-04-22" version="1">MNIQGEQIDNDIMRHRYATISELCDALNRDTDHVSILEATLGMIFFQCSVGRFDDNLPDIPWHQHFQAAISLVQKLELPRLVTESHDSMSFNMTLTAWIDILGSTVQGRAPTFAHTYREKHLSQTNSSLGLRELMGCEDRVLYLISEIACLEALKNDGMDDIQLCQHVHALGDQIGLTEIGETGPRIPYNSHGVLSPKQLSRNMTAAFRLAARIYLCSLVPGFSPSQESCVGLVAKLTQVLEFIPAGPVGFDRSLVWVYLIGGSVSTTNSPFRQYFAERAAALGDLADHGSFGRVSTLLKEVWGHVDGRFSPGGGEAHYVSWRDVMQMKGWDFLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KG22</accession>
    <name>A0A5N6KG22_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KG22"/>
    <dbReference type="OrthoDB" id="10049244at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF10">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="362" mass="40397" checksum="8B03C0764AB240EB" modified="2020-04-22" version="1">MTRLAEMFNVNHFIVSQVNPHVIPFIAKEEGAIKEDVHKDSTGGPGWVYNLTNLAKAEALHRMQVLAELGVFPNLVTKCKSILSQKYSGDITILPEINFKDFPRILKNPTSEFMVQACLSGEKATWPKLSRVWNHCAVELELDAAVQKLRTRVVFSPSEVNLRRLRTGDDSRQSMRRMGRQSADSGNLLLMSRGEDNEFIENRRSSSRPPLRATASVLDVTYRSLGYSQPRSAQRTPQFTLQLGQENEMFHFPIPPKDPLQVRNQIPDLSSAGETTFSPLSSDSDVESQADESSTELDTEEAIYGIASLNLSRQLDLFSRNHPITPGTDRVLATSPSVMRNAAGLPYSTTAISPIEKRPRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KG25</accession>
    <name>A0A5N6KG25_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">EYC80_006012</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mlax316</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KG25"/>
    <dbReference type="OrthoDB" id="47494at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="258"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAB8302647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="322" mass="36290" checksum="395AC3149762270F" modified="2020-04-22" version="1">MALHWGSQHLNSCLPDEILENIKSIDCDQYYEDEYGIMPSLSFHDAQSGETLMKLSSVGIRRVSRKKMRKLFSKGLHIRYNMRLASFTASDTTVTVKFEDGTSTSGTHLVGADGAKSLLRTSLLGDTAALTPMPYTMYNFKASFTAEQARYLKETSSFHPIMNFGTNKELKIFSMISILDVVDRKKPETWIFQLLWSVFEEDPKHREKVATMSNEEKLRFLQSNADLWADPWKSALKWVPEGTEIPADVCMLWKDPVLWDNHQGRVTLAGDAAHAMPPHRGQGLNNAIQDAANYIEAIKKINEGTCSAAEAISAYDAEQRMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHT1</accession>
    <name>A0A5N6KHT1_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_004776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHT1"/>
    <dbReference type="OrthoDB" id="258627at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8303343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="77" mass="8739" checksum="6ECE1A7363B1789E" modified="2020-04-22" version="1">MTYDPIHHPHIQPSTQIPHLNNPSAHPPLQKRSPTTEPQTRNSNNISITEWKRGEEMINAAGAVDPTADKKEYPEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KHT4</accession>
    <name>A0A5N6KHT4_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">EYC80_004690</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KHT4"/>
    <dbReference type="OrthoDB" id="2014654at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050273">
        <property type="entry name" value="GppA/Ppx_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057512">
        <property type="entry name" value="RTG2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30005">
        <property type="entry name" value="EXOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30005:SF0">
        <property type="entry name" value="RETROGRADE REGULATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23566">
        <property type="entry name" value="RTG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx/GppA phosphatase N-terminal" evidence="2">
        <location>
            <begin position="77"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="RTG2 C-terminal" evidence="3">
        <location>
            <begin position="197"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAB8303245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="368" mass="41488" checksum="8AD09FD9700F859A" modified="2020-04-22" version="1">MPFGAAKMTALLKAGDIHDIRNDLRSRFHETFQGLCGSFPKLQHLVENEGVTIYLCGGGFRGFGSMLMHTDPINPYPIPSIAGYKVSGKRFQQTKEMLQVNKKEKEKIYGMSKRRREQFPAIVEVVEGLISTVPNIKEVIFCGGGNREGVLYLKLPQEAQATHPLLLFPSIFNTNTDIDKNNNNNNNNNNNNNKNKHQQVNTNQLAKILASALPTDHPATKIFTHEILIYIVSHIWDNMANVSNLNAARALHAPISGTIAGMPGLTHDTIAILSLTMCARWENDLGKVDRGVWERSNQLKPNHRIFLYSMDRDNNQVYIIRTPGIYHLPCPCFVLPCFSYNLVRFFSILFNFNPIQSNPLSCIALHQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI50</accession>
    <name>A0A5N6KI50_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_004797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI50"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="133" mass="14731" checksum="E7B1F42E572C0019" modified="2020-04-22" version="1">MGEIPTFNVVDKGETSQGTIAELIGEIFGIKTGFQGQLVSTFAKLNMDSVVDDINEEVLGPWADLLEEAGITRPGPLTPFMEKELLKDTDLSMDGTRIEKVVGFKYDHPKITKDLLQGMIDSYIKIGWWPVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI66</accession>
    <name>A0A5N6KI66_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_006246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000003">
        <property type="protein sequence ID" value="KAB8302929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI66"/>
    <dbReference type="OrthoDB" id="63113at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8302929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="106" mass="11438" checksum="5815E912392AECF7" modified="2020-04-22" version="1">MQSSSGHRYYSGPADISYTSVQRSPPQGYPATGRAPSDSSLRNLNSPRGEIDVITIPDSSEESDSSDELGNGGQVFSEEREPERERVVPRRPVSGSGSGRRKGKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KI67</accession>
    <name>A0A5N6KI67_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MIF4G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">EYC80_004888</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mlax316</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KI67"/>
    <dbReference type="OrthoDB" id="27832at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000052">
        <property type="entry name" value="Nonsense-mediated mRNA decay factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000037">
        <property type="entry name" value="Nonsense-mediated mRNA decay factor (Upf2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.80.160:FF:000001">
        <property type="entry name" value="Nonsense-mediated mRNA decay factor (Upf2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.80.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039762">
        <property type="entry name" value="Nmd2/UPF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007193">
        <property type="entry name" value="Upf2/Nmd2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12839">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12839:SF7">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04050">
        <property type="entry name" value="Upf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G" evidence="4">
        <location>
            <begin position="519"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G" evidence="4">
        <location>
            <begin position="723"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="201"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="283"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="957"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1144"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="963"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1024"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1046"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1071"/>
            <end position="1085"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAB8303470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="1186" mass="133480" checksum="45E2F3B6A7D1A712" modified="2020-04-22" version="1">MMDVCLGNHRANVLHGPTSQIRSGLNKFIMDRKRKRELRDLNTRAWDGEKDIFAVNKSLDSSLKKNTAFIKRLRTAISAATLSTFLQEIRTLSLHKYLSEIISACYEGLCRLKSPGEVEAGVEIVSALHQRFGSAEFTEFLGWLVGKGLATPEKSLLKSLTTEAREKEEKERIVRQRVLLRVVTELWLVGVLRTLDDVARPDDASHGKESLSGPSSKAPDTKAKPNGTGKGGGAEPFPLEVLKDLLGHDRDHANLPLLVVFVKAFGWDILGVREAGYEGRKTVEEDGATKATADATEGEGEGEDEDDSLEETLPTPDSAEDTPLASPELQERFRNILNRYFEDVKTHLIRDQKAIGKQARKDSEAYVKSGQVFEDRQANYEKAVKAQERLISNAQVLAESIGAEMPDLKDADDSLALGNGGVGLVKTGDYLRGEGEGAGIWEDEDERRFYENLVDLKGKVPGMLLEDGKKKKADTDEQVGKKIEISEANSGETAALATKSTEDDQSTTITNKTIGAQVDALLARLPDLINKDLVDQAAIDFCFLNSKASRNRLIKAVQEVPKGRSDLLPSYSRLVATLGKYMPDIIKGLVDHLDQEFRSLQRRKEKEFLGQARLGNIRYLAELTKFGVVPEHVVFHCLKVSLDDFSRMNIEIICNLLENCGRYLLRNPEMSPRMTSFLETLKRKKAVQHIGQQERMLIENAVYYVDPPVRAAIQQKERTPIDLFIRKLVYSDMTTRNYARIIKSIRRLHWEESEVVTILEKVLSKPGRVKYGNIYLLAIVTGALFRYHQDFVVTVIDNVLEYIVIGLEQNDFKFNQRRIAEVKYLGELYNFRMVDHPVIFDTMYRILTFGHGGPPIPGRINPFDMPDDFFRIRLVATLLETCGIFFSRGAAGKKLDYFLSFFQYYIYTKDPMPMDIEFIVSDIYATTRPQWKLASNIEEASRAFQLAMAQDQKTAGIEKVVEPEELESDASSDEGDAGIPEGDADDASFDSDEETEVDANVDNLTSPTGNESEEENFSVTRQEEEIDPEDEADFEREYAKMMAESLDSRKFERKATFDVPLPMRRKDRETTNPSELPNETNPTNGSSGGTMAFSLLTKRGNRQQTRTVALPSDSNFAIAMKSQQAAEREEQQRIKNLVLNYDLNDGEEQDGFDKNVTTTFSRSDKSGSNRSGQRSRKLQFSDVDWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJX2</accession>
    <name>A0A5N6KJX2_MONLA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial import protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">EYC80_005416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8304074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJX2"/>
    <dbReference type="OrthoDB" id="2148490at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070096">
        <property type="term" value="P:mitochondrial outer membrane translocase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013262">
        <property type="entry name" value="OMP_MIM1/TOM13_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28241">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28241:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08219">
        <property type="entry name" value="TOM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAB8304074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="128" mass="13970" checksum="80B2F81B1F414B62" modified="2020-04-22" version="1">MSSDEQLNPLAESGITIPSDSEQYSRNEDGTSPSQSSSNSPQMILYSPPTFWGLLRGAAINLVLPFVNGLMLGFGELFAHEAAFRLGWSNTKVFPAARRSVGPGIEVKDSPIERKRREGNLDDLTSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-04-22" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A5N6KJY8</accession>
    <name>A0A5N6KJY8_MONLA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">EYC80_005339</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Monilinia laxa</name>
        <name type="common">Brown rot fungus</name>
        <name type="synonym">Sclerotinia laxa</name>
        <dbReference type="NCBI Taxonomy" id="61186"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Leotiomycetes</taxon>
            <taxon>Helotiales</taxon>
            <taxon>Sclerotiniaceae</taxon>
            <taxon>Monilinia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-06" db="EMBL/GenBank/DDBJ databases">
            <title>Genome Sequence of the Brown Rot Fungal Pathogen Monilinia laxa.</title>
            <authorList>
                <person name="De Miccolis Angelini R.M."/>
                <person name="Landi L."/>
                <person name="Abate D."/>
                <person name="Pollastro S."/>
                <person name="Romanazzi G."/>
                <person name="Faretra F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mlax316</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VIGI01000002">
        <property type="protein sequence ID" value="KAB8303988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A5N6KJY8"/>
    <dbReference type="OrthoDB" id="66510at2759"/>
    <dbReference type="Proteomes" id="UP000326757">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAB8303988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000326757"/>
        </source>
    </evidence>
    <sequence length="165" mass="18982" checksum="E6504103D7D3973B" modified="2020-04-22" version="1">MGRLRDIGCGEIGDEMYMHVWSDVLRISIHHSPFTIHHSPFTNNKSPTSLSIPNTLFIRLIYLYNDDQNQPKKNAIYMPRILAYQTTHKTSMMASHPQHKRYCSPSFTTLPSMPTHLVNVWSKTRPRLLVSIVAMLNLPILYMNPFPSEEHCAIHPSIHPSIHPS</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>